CN211563940U - Magnetic separation cleaning module - Google Patents

Magnetic separation cleaning module Download PDF

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Publication number
CN211563940U
CN211563940U CN202020054812.5U CN202020054812U CN211563940U CN 211563940 U CN211563940 U CN 211563940U CN 202020054812 U CN202020054812 U CN 202020054812U CN 211563940 U CN211563940 U CN 211563940U
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China
Prior art keywords
cleaning
magnetic separation
needle
magnetic
liquid
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CN202020054812.5U
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Chinese (zh)
Inventor
许行尚
杰弗瑞·陈
赵大强
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Nanjing Lanyu Biological Technology Co Ltd
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Nanjing Lanyu Biological Technology Co Ltd
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Abstract

The utility model discloses a magnetic separation cleaning module, which is provided with at least one magnetic separation cleaning device, wherein the magnetic separation cleaning device comprises a magnetic separation cleaning needle, a rotatable magnetic separation seat is arranged below the magnetic separation cleaning needle, and the magnetic separation seat is provided with at least one reaction cup hole; the magnetic cleaning pool comprises a cleaning liquid path and a cleaning needle liquid drainage path, and cleaning liquid enters through a cleaning liquid inlet in the cleaning liquid path and then enters into the reaction cup through a cleaning liquid sharp opening for cleaning; the magnetic separation cleaning needle is used for discharging waste liquid after cleaning in the reaction cup through the liquid discharging path of the cleaning needle. The magnetic separation cleaning module performs magnetic separation cleaning on the detection indexes, cleans unreacted substances and impurities, and waits for the detection module to detect; the cleaning needle is used for sucking and discharging the waste liquid after cleaning in the reaction cup, and the cleaning process comprises 3-5 times of liquid inlet and liquid discharge; the magnetic separation seat is a rotatable seat disc which can rotate to clean the reaction cups on the magnetic separation seat in sequence.

Description

Magnetic separation cleaning module
Technical Field
The utility model belongs to the technical field of medical equipment, especially, relate to a magnetic separation cleaning module that is arranged in full-automatic chemiluminescence immunoassay appearance of chemiluminescence diagnostic technique.
Background
The mainstream chemiluminescence product in the market needs to adopt serum or plasma as a detection sample, can not support direct and automatic detection of a whole blood sample, has long first sample report time and long total diagnosis time, hardly meets the requirement of detection turnover time, has long total waiting time, can aggravate the pain of a patient, easily causes the conflict emotion of family members or the patient, and is not beneficial to the treatment of subsequent patients.
Chinese patent document CN106918715A discloses a chemiluminescent diagnostic device comprising: a base having a mounting surface; the sampling needle module comprises a sampling mechanism which is rotatably arranged relative to the base and a driving mechanism which is arranged on the base and is used for driving the sampling mechanism to rotate and lift; a magnetic bead reagent pre-incubation module comprising a pre-incubation tray and pre-incubation heating means for heating the pre-incubation tray, the pre-incubation heating means being disposed at the bottom of the pre-incubation tray; the pre-incubation disc is arranged around the rotating axis of the sampling mechanism and is positioned in a sampling area of the sampling mechanism; the incubation cleaning module comprises an incubation tray, an incubation heating device for heating the incubation tray, a magnetic separation component and a cleaning station component, wherein the incubation heating device is arranged at the bottom of the incubation tray, the magnetic separation component is sleeved at the outer edge of the incubation tray, the cleaning station component comprises a driving component and a cleaning needle fixed on the driving component, the cleaning needle is arranged above the incubation tray and can be matched with an inner cavity of an incubation reaction cup on the incubation tray in a working state; and the data analysis module comprises an industrial personal computer and a touch display screen for data analysis.
However, the chemiluminescence diagnostic device in the technical scheme has the defects of not ideal cleaning in the specific use process, low automation degree and great defects.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a magnetic separation cleaning module.
In order to solve the technical problem, the utility model adopts the technical scheme that the magnetic separation cleaning module is provided with at least one magnetic separation cleaning device, the magnetic separation cleaning device comprises a magnetic separation cleaning needle, a rotatable magnetic separation seat is arranged below the magnetic separation cleaning needle, and the magnetic separation seat is provided with at least one reaction cup hole; the magnetic cleaning pool comprises a cleaning liquid path and a cleaning needle liquid drainage path, and cleaning liquid enters through a cleaning liquid inlet in the cleaning liquid path and then enters into the reaction cup through a cleaning liquid sharp opening for cleaning; the magnetic separation cleaning needle is used for discharging waste liquid after cleaning in the reaction cup through the liquid discharging path of the cleaning needle.
The magnetic separation cleaning module performs magnetic separation cleaning on the detection indexes, cleans unreacted substances and impurities, and waits for the detection module to detect; the reaction cup hole on the magnetic separation seat is used for placing a reaction cup after incubation reaction of the incubation module, and a plurality of reaction cup holes can be arranged; it should be noted that when the cleaning solution passes through the cleaning solution sharp opening, the cleaning needle can be cleaned at the same time; the cleaning needle is used for sucking and discharging the waste liquid after cleaning in the reaction cup, and the cleaning process comprises 3-5 times of liquid inlet and liquid discharge; the magnetic separation seat is a rotatable seat disc which can rotate to clean the reaction cups on the magnetic separation seat in sequence.
Preferably, the magnetic separation cleaning needle is controlled by a magnetic cleaning lifting motor to move up and down, the magnetic separation cleaning device is further provided with a lifting limiting structure, the lifting limiting structure comprises a magnetic cleaning lifting upper plate and a magnetic cleaning lifting lower plate, and a limiting optocoupler, a cleaning needle lifting blocking piece, a lifting screw rod and a guide rod are arranged between the magnetic cleaning lifting upper plate and the magnetic cleaning lifting lower plate; sliding connection has the slider on the lift lead screw, and magnetism washs elevator motor drive the lift lead screw rotates, the slider with guide bar and magnetic separation wash the needle and be connected, the magnetic separation washs the needle and is in under the drive of slider along guide bar up-and-down motion.
Preferably, the magnetic separation seat is driven to rotate by a magnetic separation seat rotating motor, and a rotation limiting structure is arranged below the magnetic separation seat rotating motor; and a magnet is arranged in the magnetic separation seat.
And a magnet is arranged in the magnetic separation seat and is used for adsorbing index substances to be detected in the sample.
Drawings
The following is a more detailed description of embodiments of the present invention with reference to the accompanying drawings:
FIG. 1 is a perspective view showing the installation state of the magnetic separation cleaning module of the present invention;
FIG. 2 is a partial cross-sectional view of the magnetic separation cleaning module of FIG. 1 showing a cleaning fluid path;
FIG. 3 is a perspective view of a magnetic separation cleaning module;
FIG. 4 is a cross-sectional view of a magnetic separation cleaning apparatus;
FIG. 5 is a perspective view of the magnetic separation cleaning apparatus;
FIG. 6 is a partial cut-away perspective view of a magnetic separation cleaning device in a magnetic separation cleaning module;
wherein: 1-a magnetic separation cleaning module; 101-magnetic separation cleaning needle; 102-a magnetic separation seat; 10201-reaction cup well; 10202-spare reaction cup wells; 10203-magnet; 103-magnetic cleaning pool; 10301-cleaning fluid path; 10302-cleaning the needle drainage path; 104-a cleaning solution inlet; 105-cleaning fluid tip; 106-magnetic cleaning lifting motor; 107-lifting limit structure; 10701 magnetically cleaning the upper plate; 10702 magnetic cleaning of the lifting plate; 10703-limit optocoupler; 10704 cleaning needle lifting and lowering blocking piece; 10705-lifting lead screw; 10706-a guide bar; 10707-a slider; 108-magnetic separation seat rotating electrical machine; 109-rotation limiting structure.
Detailed Description
As shown in fig. 1, the magnetic separation cleaning module 1 of the present embodiment has at least one magnetic separation cleaning device, the magnetic separation cleaning device includes a magnetic separation cleaning needle 601 (the present embodiment is equipped with 4 magnetic separation cleaning devices, there are 4 magnetic separation cleaning needles 101 in total), a rotatable magnetic separation seat 102 is disposed below the magnetic separation cleaning needle 101, the magnetic separation seat 102 has at least one reaction cup hole 10201, in the present embodiment, each magnetic separation seat 102 is provided with 4 reaction cup holes 10201 and 1 spare reaction cup hole 10202; the magnetic cleaning device also comprises a magnetic cleaning pool 103, wherein the magnetic cleaning pool 103 comprises a cleaning liquid path 10301 and a cleaning needle drainage liquid path 10302, and cleaning liquid enters through a cleaning liquid inlet 104 in the cleaning liquid path 10301 and then enters the reaction cup 5 through a cleaning liquid sharp opening 105 for cleaning, as shown in FIG. 2; the magnetic separation cleaning needle 101 is used for discharging waste liquid after cleaning in the reaction cup through the cleaning needle liquid discharge path 10302 (the position is shown in fig. 2).
When cleaning liquid enters through the cleaning liquid inlet 104, the magnetic separation cleaning needle 101 is lifted from the cleaning liquid sharp opening 105, the cleaning liquid enters the reaction cup through the cleaning liquid sharp opening 105, and the cleaning liquid can simultaneously clean the magnetic separation cleaning needle 101 when passing through the cleaning liquid sharp opening 105; the magnetic separation cleaning needle 101 is used for sucking and discharging waste liquid after cleaning in the reaction cup. The cleaning process is liquid feeding and draining for 3-5 times. The magnetic separating seat 102 rotates to clean each reaction cup in turn, as shown in fig. 4. The magnetic separation cleaning needle 101, the magnetic separation seat 102, the magnetic cleaning pool 103, the magnetic cleaning lifting motor 106 and other components form a magnetic separation cleaning device in the magnetic separation cleaning module 1, and a plurality of magnetic separation cleaning devices can be stacked and assembled as shown in fig. 1 and 3 according to the requirements of the instrument.
The magnetic separation cleaning needle 101 is controlled by a magnetic cleaning lifting motor 106 to move up and down, as shown in fig. 5, the magnetic separation cleaning module 1 is further provided with a lifting limit structure 107, the lifting limit structure 107 comprises a magnetic cleaning lifting upper plate 10701 and a magnetic cleaning lifting lower plate 10702, and a limit optical coupler 10703, a cleaning needle lifting blocking piece 10704, a lifting lead screw 10705 and a guide rod 10706 are arranged between the magnetic cleaning lifting upper plate 10701 and the magnetic cleaning lifting lower plate 10702; sliding connection has slider 10707 on the lift lead screw 10705, and magnetism washs elevator motor 106 drive lift lead screw 10705 rotates, slider 10707 with guide bar 10706 and magnetism separation wash needle 101 and connect, magnetism separation wash needle 101 be in along under slider 10707's the drive guide bar 10706 up-and-down motion.
The magnetic separation seat 102 is driven by a magnetic separation seat rotating motor 108 to rotate, and a rotation limiting structure 109 is arranged below the magnetic separation seat rotating motor 108; a magnet 10203 (shown in fig. 2) is disposed within the magnetic separator block 102.
The magnetic separation seat 102 controls the rotation movement through a magnetic separation seat rotating motor 108, each magnetic separation seat 102 is provided with 4 reaction cup holes 10201 and 1 standby reaction cup hole 10202, the number of the magnetic separation seats 102 is set according to the requirement, and the lower part of each reaction cup seat is provided with a magnet 10203 for adsorbing index substances to be detected in a sample.
The magnetic separation cleaning module 1 is mainly used for carrying out magnetic separation cleaning on the detection indexes and waiting for entering the detection module 7 for detection.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (3)

1. A magnetic separation cleaning module is characterized by comprising at least one magnetic separation cleaning device, wherein the magnetic separation cleaning device comprises a magnetic separation cleaning needle, a rotatable magnetic separation seat is arranged below the magnetic separation cleaning needle, and the magnetic separation seat is provided with at least one reaction cup hole; the magnetic cleaning pool comprises a cleaning liquid path and a cleaning needle liquid drainage path, and cleaning liquid enters through a cleaning liquid inlet in the cleaning liquid path and then enters into the reaction cup through a cleaning liquid sharp opening for cleaning; the magnetic separation cleaning needle is used for discharging waste liquid after cleaning in the reaction cup through the liquid discharging path of the cleaning needle.
2. The magnetic separation cleaning module according to claim 1, wherein the magnetic separation cleaning needle is controlled by a magnetic cleaning lifting motor to move up and down, the magnetic separation cleaning device is further provided with a lifting limit structure, the lifting limit structure comprises a magnetic cleaning lifting upper plate and a magnetic cleaning lifting lower plate, and a limit optical coupler, a cleaning needle lifting baffle, a lifting screw rod and a guide rod are arranged between the magnetic cleaning lifting upper plate and the magnetic cleaning lifting lower plate; sliding connection has the slider on the lift lead screw, and magnetism washs elevator motor drive the lift lead screw rotates, the slider with guide bar and magnetic separation wash the needle and be connected, the magnetic separation washs the needle and is in under the drive of slider along guide bar up-and-down motion.
3. The magnetic separation cleaning module according to claim 1, wherein the magnetic separation seat is driven to rotate by a magnetic separation seat rotating motor, and a rotation limiting structure is arranged below the magnetic separation seat rotating motor; and a magnet is arranged in the magnetic separation seat.
CN202020054812.5U 2020-01-12 2020-01-12 Magnetic separation cleaning module Active CN211563940U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020054812.5U CN211563940U (en) 2020-01-12 2020-01-12 Magnetic separation cleaning module

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020054812.5U CN211563940U (en) 2020-01-12 2020-01-12 Magnetic separation cleaning module

Publications (1)

Publication Number Publication Date
CN211563940U true CN211563940U (en) 2020-09-25

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ID=72555901

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202020054812.5U Active CN211563940U (en) 2020-01-12 2020-01-12 Magnetic separation cleaning module

Country Status (1)

Country Link
CN (1) CN211563940U (en)

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