CN211528436U - Detection module - Google Patents

Detection module Download PDF

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Publication number
CN211528436U
CN211528436U CN202020054803.6U CN202020054803U CN211528436U CN 211528436 U CN211528436 U CN 211528436U CN 202020054803 U CN202020054803 U CN 202020054803U CN 211528436 U CN211528436 U CN 211528436U
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China
Prior art keywords
detection
reaction cup
baffle
detection module
pipeline
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CN202020054803.6U
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Chinese (zh)
Inventor
许行尚
杰弗瑞·陈
赵大强
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Nanjing Lanyu Biological Technology Co Ltd
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Nanjing Lanyu Biological Technology Co Ltd
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Abstract

The utility model discloses a detection module, which comprises a detection chamber, a PMT and a photon counter; the reaction cup is clamped into a detection reaction cup seat of the detection chamber, the first excitation liquid pipeline and the second excitation liquid pipeline are sequentially added into the reaction cup, waste liquid is discharged through a waste liquid discharge pipeline of the detection module after reaction, an optical signal is collected and converted into an electric signal through the PMT and the photon counter, and a detection result is obtained through analysis. Preferably, the detection chamber switch baffle is arranged below the top cover of the detection chamber, the baffle motion motor drives the baffle motor to rotate the connecting column, so that the detection chamber switch baffle moves back and forth under the synergistic action of the baffle motion matching groove, the baffle through hole of the detection chamber switch baffle and the reaction cup moving hole coincide or are staggered with the baffle through hole, and the detection chamber is opened or closed with the baffle through hole.

Description

Detection module
Technical Field
The utility model belongs to the technical field of medical equipment, especially, relate to a detection module that is arranged in full-automatic chemiluminescence immunoassay appearance of chemiluminescence diagnostic technique.
Background
The mainstream chemiluminescence product in the market needs to adopt serum or plasma as a detection sample, can not support direct and automatic detection of a whole blood sample, has long first sample report time and long total diagnosis time, hardly meets the requirement of detection turnover time, has long total waiting time, can aggravate the pain of a patient, easily causes the conflict emotion of family members or the patient, and is not beneficial to the treatment of subsequent patients.
Chinese patent document CN106918715A discloses a chemiluminescent diagnostic device comprising: a base having a mounting surface; the sampling needle module comprises a sampling mechanism which is rotatably arranged relative to the base and a driving mechanism which is arranged on the base and is used for driving the sampling mechanism to rotate and lift; a magnetic bead reagent pre-incubation module comprising a pre-incubation tray and pre-incubation heating means for heating the pre-incubation tray, the pre-incubation heating means being disposed at the bottom of the pre-incubation tray; the pre-incubation disc is arranged around the rotating axis of the sampling mechanism and is positioned in a sampling area of the sampling mechanism; the incubation cleaning module comprises an incubation tray, an incubation heating device for heating the incubation tray, a magnetic separation component and a cleaning station component, wherein the incubation heating device is arranged at the bottom of the incubation tray, the magnetic separation component is sleeved at the outer edge of the incubation tray, the cleaning station component comprises a driving component and a cleaning needle fixed on the driving component, the cleaning needle is arranged above the incubation tray and can be matched with an inner cavity of an incubation reaction cup on the incubation tray in a working state; and the data analysis module comprises an industrial personal computer and a touch display screen for data analysis.
However, the detection module of the chemiluminescence diagnostic apparatus in the above technical scheme is not ideal in the specific use process, and has great defects.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a detection module.
In order to solve the technical problem, the utility model adopts the technical proposal that the detection module comprises a detection chamber, a PMT and a photon counter; the reaction cup is clamped into a detection reaction cup seat of the detection chamber, the first excitation liquid pipeline and the second excitation liquid pipeline are sequentially added into the reaction cup, waste liquid is discharged through a waste liquid discharge pipeline of the detection module after reaction, an optical signal is collected and converted into an electric signal through the PMT and the photon counter, and a detection result is obtained through analysis.
Preferably, this detection module is still including exciting liquid filling and waste liquid pipe elevating movement motor, the simple and easy lead screw up-and-down motion of exciting liquid filling and waste liquid pipe elevating movement motor drive, simple and easy lead screw and detection module guide bar sliding connection drive excite liquid pipeline one, excite liquid pipeline two and arrange the waste liquid pipeline and do not move from top to bottom along the detection module guide bar respectively, the detection module guide bar is connected with the guide bar fixed block, the detection module guide bar is connected through the connection piece respectively excite liquid pipeline one, excite liquid pipeline two and arrange the waste liquid pipeline, set up spacing separation blade on the connection piece, cooperate with the opto-coupler for the spacing of upward movement.
Preferably, when the reaction cup is clamped to the detection reaction cup seat of the detection chamber, the switch baffle of the detection chamber moves, so that the reaction cup moving hole is superposed with the through hole of the baffle on the switch baffle of the detection chamber, and the reaction cup is placed in the reaction chamber; the reaction cup lifting control motor drives the motor to rotate the connecting column to drive the ejector rod slide glass connecting block to move up and down under the synergistic action of the ejector rod moving matching groove, and the ejector rod slide glass is fixedly connected to the ejector rod slide glass connecting block; the ejector rod slide glass is connected with the ejector rod of the reaction cup, the ejector rod of the reaction cup moves up and down, and the reaction cup is taken into a position detection reaction cup.
Preferably, the detection chamber switch baffle is arranged below the top cover of the detection chamber, the baffle motion motor drives the baffle motor to rotate the connecting column, so that the detection chamber switch baffle moves back and forth under the synergistic action of the baffle motion matching groove, the baffle through hole of the detection chamber switch baffle and the reaction cup moving hole coincide or are staggered with the baffle through hole, and the detection chamber is opened or closed with the baffle through hole.
Through the structure, the detection chamber is ensured to be a darkroom, and the light-resistant reaction is ensured.
Preferably, the excitation liquid pipeline I, the excitation liquid pipeline II and the waste liquid discharge pipeline all penetrate through the top cover of the detection chamber, and excitation liquid is added into a reaction cup in the detection reaction cup seat; the waste liquid discharge pipeline is long and can be inserted below the liquid level of the reaction cup for sucking and discharging liquid.
Preferably, the excitation liquid filling and waste liquid pipe lifting motion motor drives the driving wheel to drive 3 driven wheels to rotate through a belt, and the excitation liquid pipeline I, the excitation liquid pipeline II and the waste liquid discharge pipeline are all provided with one driven wheel; the simple screw rod is driven by the driven wheel to move up and down, and the simple screw rod is connected with the detection module guide rod in a sliding mode, so that the excitation liquid pipeline I, the excitation liquid pipeline II and the waste liquid discharge pipeline are driven to move up and down along the detection module guide rod.
Preferably, the bottom hole of the detection reaction cup position is smaller than the diameter of the cross section of the reaction cup and is matched with the diameter of the reaction cup ejector rod, the reaction cup ejector rod moves downwards to penetrate through the hole of the detection reaction cup position, and the reaction cup is positioned.
Drawings
The following is a more detailed description of embodiments of the present invention with reference to the accompanying drawings:
FIG. 1 is a perspective view of the detection module of the present invention;
FIG. 2 is a perspective view of the detection module with the detection chamber housing removed;
FIG. 3 is a schematic view of a detection module showing a partial structure of an excitation liquid pipeline I, an excitation liquid pipeline II and a waste liquid discharge pipeline;
FIG. 4 is a diagram showing the mounting relationship of the shutter switch of the detection chamber with the top cover of the detection module removed;
FIG. 5 is a schematic diagram showing the movement state of the lift pins of the reaction cup in the detection module;
FIG. 6 is a schematic view of a switch baffle of the detection chamber in the detection module;
FIG. 7 is a schematic bottom view of a switch baffle of the detection chamber of the detection module;
FIG. 8 is a cross-sectional view of a detection module;
wherein: 1-a detection module; 101-a detection chamber; 10101-detection chamber top cover; 102-PMT; 103-photon counter; 104-detection reaction cup seat; 105-exciting liquid pipeline I; 106-excitation liquid pipeline II; 107-waste liquid discharge pipeline; 108-exciting liquid filling and waste liquid pipe lifting movement motor; 10801-a drive wheel; 10802-driven wheel; 10803-belt; 109-simple screw rod; 1010-detection module guide bar; 1011-guide bar fixing block; 1012-connecting sheets; 1013-limiting blocking piece; 1014-optical coupling; 1015-detection chamber switch baffle; 101501-baffle through holes; 1016-reaction cup transfer hole; 1017-a reaction cup lifting control motor; 1018-motor rotation connection column; 1019-mandril slide connecting block; 1020-the ejector pin moves the mating slot; 1021-mandrel slide; 1022-reaction cup top rod; 1023-detecting the reaction cup position; 1024-a barrier motion motor; 1025-baffle motor rotation connection post; 1026 — baffle kinematic fit groove; 1027-detection reaction cup holder rotating motor; 102701 — rotating capstan; 102702 — rotating the driven wheel.
Detailed Description
As shown in fig. 1 and 4, the detection module 1 of the present embodiment includes a detection chamber 101, a PMT 102, and a photon counter 103; the reaction cup is clamped into a detection reaction cup seat 104 (shown in fig. 2) of the detection chamber 101, an excitation liquid pipeline I105 and an excitation liquid pipeline II 106 are sequentially added into the reaction cup, waste liquid is discharged through a waste liquid discharge pipeline 107 of the detection module 1 after reaction, an optical signal is collected and converted into an electric signal through the PMT 102 and the photon counter 103, and a detection result is obtained through analysis; in the present embodiment, specifically, the reaction cup is clamped into the detection reaction cup holder 104 (as shown in fig. 2) by the action of the detection chamber switch baffle 1015 and the reaction cup push rod 1022, the detection reaction cup holder rotating motor 1027 rotates, as shown in fig. 8, the rotating motor 102701 is provided with a rotating driving wheel 102701 with a gear, and the rotating driving wheel 102701 drives a rotating driven wheel 102702 located below the detection reaction cup holder; the reaction cup is driven to rotate, the first excitation liquid pipeline 105, the second excitation liquid pipeline 106 and the waste liquid discharge pipeline 107 move up and down, the excitation liquids 1 and 2 are sequentially added into the reaction cup, and waste liquid is discharged after reaction.
The detection module 1 further comprises an excitation liquid filling and waste liquid pipe lifting motion motor 108, the excitation liquid filling and waste liquid pipe lifting motion motor 108 drives a simple screw rod 109 to move up and down, the simple screw rod 109 is slidably connected with a detection module guide rod 1010 to drive a first excitation liquid pipeline 105, a second excitation liquid pipeline 106 and a waste liquid discharge pipeline 107 to respectively move up and down along the detection module guide rod 1010 (it should be noted that the first excitation liquid pipeline 105, the second excitation liquid pipeline 106 and the waste liquid discharge pipeline 107 are respectively provided with a simple screw rod and a detection module guide rod which are assembled together), the detection module guide rod 1010 is connected with a guide rod fixing block 1011, the detection module guide rod 1010 is respectively connected with the first excitation liquid pipeline 105, the second excitation liquid pipeline 106 and the waste liquid discharge pipeline 107 through a connecting sheet 1012, a limit baffle 1013 is arranged on the connecting sheet 1012 and is matched with an optical coupler 1014 (limit optical coupler), for limiting the upward movement, as shown in fig. 3. Specifically, excitation liquid filling and waste liquid pipe elevating movement motor 108 starts, and action wheel 10801 passes through belt 10803 and drives 3 and follows driving wheel 10802 (excitation liquid pipeline 105, excitation liquid pipeline 106 and waste liquid discharge pipeline 107, three pipeline, all be equipped with one from the driving wheel) and rotate to make simple and easy lead screw 109 up-and-down motion, simple and easy lead screw 109 and detection module guide bar 1010 sliding connection, thereby drive 3 liquid way pipes along detection module guide bar 1010 up-and-down motion.
When the reaction cup 9 is clamped into the detection reaction cup seat 104 of the detection chamber 101 by the manipulator and the transfer module 5, the detection chamber switch baffle 1015 moves to make the reaction cup moving hole 1016 coincide with the baffle through hole 101501 on the detection chamber switch baffle 1015, and the reaction cup 9 is placed in; meanwhile, the detection reaction cup holder 104 is deep, and the reaction cup ejector rod 1022 is required to be lifted to stop the reaction cup 9 to move downwards to the detection reaction cup position 1023, and then excitation liquid is added. The reaction cup mandril has the following motion principle: as shown in fig. 5 and 2, the cuvette lift control motor 1017 is started, the cuvette lift control motor 1017 drives the motor to rotate the connecting column 1018, so as to drive the ejector pin slide glass connecting block 1019 to move up and down under the synergistic action of the ejector pin moving matching groove 1020, and the ejector pin slide glass 1021 is fixedly connected to the ejector pin slide glass connecting block 1019; the push rod slide plate 1021 is connected with a reaction cup push rod 1022, the reaction cup push rod 1022 moves up and down and is connected with a reaction cup position 1023 for position detection; it should be noted that the bottom hole of the detecting cup 1023 is smaller than the cross-sectional diameter of the reaction cup and matches with the diameter of the reaction cup top bar 1022, so that the reaction cup top bar 1022 moves downward to pass through the hole of the detecting cup 1023 and the reaction cup is in place.
Detection room switch baffle 1015 installs in detection room top cap 10101 below, and baffle motion motor 1024 starts, as shown in fig. 6, 7, baffle motion motor 1024 drive baffle motor rotation spliced pole 1025 and rotate, makes detection room switch baffle 1015 move back and forth under the synergistic action of baffle motion cooperation groove 1026, the baffle through-hole 101501 of detection room switch baffle 1015 with reaction cup moves and gets hole 1016 coincidence or stagger thereupon, and detection room 101 opens or closes thereupon, guarantees that detection room 101 is the darkroom, guarantees to keep out of the sun the reaction.
The first excitation liquid pipeline 105, the second excitation liquid pipeline 106 and the waste liquid discharge pipeline 107 all penetrate through the top cover 10101 of the detection chamber, as shown in fig. 7; adding exciting liquid into the reaction cup in the detection reaction cup seat 104; the waste liquid discharge pipeline 107 is long and can be inserted below the liquid level of the reaction cup for sucking and discharging liquid.
In this embodiment, the detection module 1 is mainly used for detecting the reaction cup after magnetic cleaning by filling excitation liquid and discharging liquid.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (7)

1. A detection module is characterized by comprising a detection chamber, a PMT and a photon counter; the reaction cup is clamped into a detection reaction cup seat of the detection chamber, the first excitation liquid pipeline and the second excitation liquid pipeline are sequentially added into the reaction cup, waste liquid is discharged through a waste liquid discharge pipeline of the detection module after reaction, an optical signal is collected and converted into an electric signal through the PMT and the photon counter, and a detection result is obtained through analysis.
2. The detection module according to claim 1, further comprising an excitation liquid filling and waste liquid pipe lifting motor, wherein the excitation liquid filling and waste liquid pipe lifting motor drives a simple screw rod to move up and down, the simple screw rod is slidably connected with a detection module guide rod to drive the excitation liquid pipeline I, the excitation liquid pipeline II and the waste liquid discharge pipeline to move up and down along the detection module guide rod respectively, the detection module guide rod is connected with a guide rod fixing block, the detection module guide rod is connected with the excitation liquid pipeline I, the excitation liquid pipeline II and the waste liquid discharge pipeline respectively through connecting pieces, and the connecting pieces are provided with limiting blocking pieces which are matched with the optical couplers and used for limiting the upward movement.
3. The detection module according to claim 2, wherein when the reaction cup is clamped to the detection reaction cup holder of the detection chamber, the detection chamber switch baffle moves to make the reaction cup moving hole coincide with the baffle through hole on the detection chamber switch baffle, and the reaction cup is placed in the reaction chamber; the reaction cup lifting control motor drives the motor to rotate the connecting column to drive the ejector rod slide glass connecting block to move up and down under the synergistic action of the ejector rod moving matching groove, and the ejector rod slide glass is fixedly connected to the ejector rod slide glass connecting block; the ejector rod slide glass is connected with the ejector rod of the reaction cup, the ejector rod of the reaction cup moves up and down, and the reaction cup is taken into a position detection reaction cup.
4. The detection module according to claim 3, wherein the detection chamber switch baffle is mounted below the detection chamber top cover, the baffle movement motor drives the baffle motor to rotate the connecting column, so that the detection chamber switch baffle moves back and forth under the cooperation of the baffle movement matching groove, the baffle through hole of the detection chamber switch baffle coincides with or is staggered with the reaction cup moving hole, and the detection chamber is opened or closed accordingly.
5. The detection module according to claim 4, wherein the first exciting liquid pipeline, the second exciting liquid pipeline and the waste liquid pipeline all penetrate through the top cover of the detection chamber, and exciting liquid is added into the reaction cup in the detection reaction cup seat; the waste liquid discharge pipeline is long and can be inserted below the liquid level of the reaction cup for sucking and discharging liquid.
6. The detection module according to claim 2, wherein the excitation liquid filling and waste liquid pipe lifting motion motor drives the driving wheel to drive 3 driven wheels to rotate through a belt, wherein the excitation liquid pipeline I, the excitation liquid pipeline II and the waste liquid discharge pipeline are provided with one driven wheel; the driven wheel drives the simple screw rod to move up and down.
7. The detection module of claim 5, wherein the bottom hole of the detection cuvette site is smaller than the cross-sectional diameter of the detection cuvette and matches the diameter of the top rod of the detection cuvette, and the top rod of the detection cuvette is moved downward to pass through the hole of the detection cuvette site and the detection cuvette site.
CN202020054803.6U 2020-01-12 2020-01-12 Detection module Active CN211528436U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020054803.6U CN211528436U (en) 2020-01-12 2020-01-12 Detection module

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Application Number Priority Date Filing Date Title
CN202020054803.6U CN211528436U (en) 2020-01-12 2020-01-12 Detection module

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CN211528436U true CN211528436U (en) 2020-09-18

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113324981A (en) * 2021-06-04 2021-08-31 吴文华 Full-automatic chemiluminescent inspection device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113324981A (en) * 2021-06-04 2021-08-31 吴文华 Full-automatic chemiluminescent inspection device
CN113324981B (en) * 2021-06-04 2023-11-07 吴文华 Chemiluminescence full-automatic inspection device

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