CN217781167U

CN217781167U - Quick nucleic acid extraction instrument

Info

Publication number: CN217781167U
Application number: CN202221391450.4U
Authority: CN
Inventors: 贾樱
Original assignee: Air Force Medical University of PLA
Current assignee: Air Force Medical University of PLA
Priority date: 2022-06-06
Filing date: 2022-06-06
Publication date: 2022-11-11
Anticipated expiration: 2032-06-06

Abstract

The utility model discloses a nucleic acid draws appearance fast belongs to the nucleic acid and draws technical field fast. Nucleic acid draws appearance fast, including the work box, install the nucleic acid extractor in the work box, still include: the storage box is connected to the work box in a sliding mode, a plurality of placing holes are formed in the storage box, placing bottles are placed in the placing holes, and bottle covers are connected to the placing bottles in a threaded mode; the utility model discloses can be through holding the bottle of placing that the box will deposit the sample and put into the work box, and carry out sealed virus killing to the work box, make the interior sterile environment that is of work box, then through first motor, the second motor, the electro-magnet, the third motor, electric telescopic handle and nucleic acid extractor mutually support, remove placing the bottle, uncap, nucleic acid draws and closes the lid and remove to holding the box and originally place downtheholely, thereby can avoid having now to draw the appearance through nucleic acid fast and take place the contact with the air and lead to the sample to be polluted and send the not accurate problem of nucleic acid extraction result to take place.

Description

Quick nucleic acid extraction instrument

Technical Field

The utility model relates to a nucleic acid draws technical field fast, especially relates to nucleic acid draws appearance fast.

Background

The nucleic acid extractor is an instrument for automatically finishing the work of extracting the nucleic acid of a sample by using a matched nucleic acid extraction reagent, and is widely applied to various fields of disease control centers, clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microorganism detection, food safety detection, animal husbandry, molecular biology research and the like.

The appearance is drawed fast to nucleic acid on the market at present needs the manual work to hold the bottle lid of placing of sample to open in the use more, then will open the bottle of placing after and put into the appearance of drawing fast and carry out nucleic acid extraction, can make sample and air contact in this operation process, easily makes the bacterium in the air sneak into and places the bottle in the contaminated sample to the result that leads to nucleic acid extraction is accurate inadequately.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving need among the prior art artifical bottle of placing that will hold the sample to open the back will place the bottle and put into the quick appearance of drawing of nucleic acid, it is easy in this operation process that the sample leads to the not accurate problem of extraction result by the bacterial contamination in the air, and the quick appearance of drawing of nucleic acid of proposing.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

nucleic acid draws appearance fast, including the work box, install the nucleic acid extractor in the work box, still include: the storage box is connected to the working box in a sliding mode, a plurality of placing holes are formed in the storage box, placing bottles are placed in the placing holes, bottle caps are connected to the placing bottles in a threaded mode, hexagonal grooves are formed in the bottle caps, and permanent magnets are fixedly connected to the hexagonal grooves; the guide plate is connected in the working box in a sliding mode, a sliding block is connected to the guide plate in a sliding mode, the sliding block is connected with a first gear in a rotating mode, the bottom of the first gear is fixedly connected with an electromagnet, and the electromagnet is matched with a permanent magnet; the temporary placing support frame is fixedly connected to the telescopic end of the electric telescopic rod, the temporary placing support frame is fixedly connected to the temporary placing support frame, the limiting sleeve is fixedly connected to the temporary placing support frame, the temporary placing support frame and the limiting sleeve are matched with the placing bottle, and the nucleic acid extractor is positioned above the limiting sleeve; and the rotating assembly is used for driving the first gear to rotate.

In order to facilitate the driving of the guide plate to slide in the working box, preferably, a second threaded rod is rotatably connected in the working box, a connecting block is fixedly connected to the bottom of the guide plate, the connecting block is in threaded connection with the second threaded rod, a limiting sliding groove is formed in the working box, and two ends of the guide plate are slidably connected in the limiting sliding groove.

In order to facilitate the driving of the second threaded rod to rotate, a second motor is fixedly connected in the working box, and the output end of the second motor is fixedly connected with the second threaded rod.

In order to facilitate the sliding of the driving sliding block on the guide plate, preferably, a support plate is fixedly connected to the guide plate, a first threaded rod is rotatably connected to the support plate, and the sliding block is in threaded connection with the first threaded rod.

In order to facilitate the rotation of the first threaded rod, a first motor is fixedly connected to the guide plate, and the output end of the first motor is fixedly connected with the first threaded rod.

In order to facilitate driving the first gear to rotate, preferably, the rotating assembly includes a third motor, the third motor is fixedly connected in the work box, a second gear is fixedly connected to an output end of the third motor, and the second gear is matched with the first gear.

The device in not relate to the part all the same with prior art or can adopt prior art to realize, the utility model discloses can be through holding the box and will deposit the bottle of placing of sample and put into the work box, and carry out sealed virus killing to the work box, make and be aseptic environment in the work box, then through first motor, the second motor, the electro-magnet, the third motor, electric telescopic handle and nucleic acid extractor mutually support, move placing the bottle, uncap, nucleic acid extraction and close the lid and remove to holding the box and originally place downtheholely, thereby can avoid having now to take place the contact through the quick extraction appearance of nucleic acid in-process sample and air and lead to the sample contaminated to lead to the problem that the nucleic acid extraction result is not accurate enough.

Drawings

FIG. 1 is a schematic structural diagram I of a rapid nucleic acid extraction apparatus according to the present invention;

FIG. 2 is a schematic structural diagram of a second rapid nucleic acid extractor according to the present invention;

FIG. 3 is a schematic structural view of a guide plate part of the rapid nucleic acid extractor of the present invention;

FIG. 4 is a schematic structural view of a bottle containing part of the rapid nucleic acid extractor of the present invention;

FIG. 5 is a schematic view of the temporary support frame of the rapid nucleic acid extractor of the present invention.

In the figure: 1. a work box; 11. a nucleic acid extractor; 3. a containing box; 31. placing holes; 4. placing the bottle; 41. a bottle cap; 42. a permanent magnet; 5. a guide plate; 51. a support plate; 52. connecting blocks; 6. a slider; 61. a first motor; 62. a first threaded rod; 63. a first gear; 64. an electromagnet; 7. a second threaded rod; 71. a second motor; 8. a third motor; 81. a second gear; 9. temporarily placing the support frame; 91. a position limiting sleeve; 92. an electric telescopic rod.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.

Example (b):

referring to fig. 1-4, the instrument for rapidly extracting nucleic acid comprises a work box 1, a nucleic acid extractor 11 is installed in the work box 1, and the instrument further comprises: the storage box 3 is connected to the work box 1 in a sliding mode, a plurality of storage holes 31 are formed in the storage box 3, storage bottles 4 are placed in the storage holes 31, bottle caps 41 are connected to the storage bottles 4 in a threaded mode, hexagonal grooves are formed in the bottle caps 41, and permanent magnets 42 are fixedly connected to the hexagonal grooves; the guide plate 5 is connected in the work box 1 in a sliding mode, the guide plate 5 is connected with the sliding block 6 in a sliding mode, the sliding block 6 is connected with the first gear 63 in a rotating mode, the bottom of the first gear 63 is fixedly connected with the electromagnet 64, and the electromagnet 64 is matched with the permanent magnet 42; the temporary placing support frame 9 is fixedly connected to the telescopic end of the electric telescopic rod 92, the limiting sleeve 91 is fixedly connected to the temporary placing support frame 9, the temporary placing support frame 9 and the limiting sleeve 91 are matched with the placing bottle 4, and the nucleic acid extractor 11 is positioned above the limiting sleeve 91; and the rotating assembly is used for driving the first gear 63 to rotate.

The internal rotation of work box 1 is connected with second threaded

rod

7, and 5 bottom fixedly connected with connecting block 52 of deflector, connecting block 52 threaded connection have been seted up spacing spout in the work box 1 on second threaded

rod

7, 5 both ends sliding connection of deflector in spacing spout, fixedly connected with second motor 71 in the work box 1, second motor 71 output and second threaded rod 7 fixed connection.

Fixedly connected with backup pad 51 on deflector 5 rotates on backup pad 51 and is connected with first threaded

rod

62, and 6 threaded connection of slider is on first threaded rod 62, the first motor of fixedly connected with 61, the output of first motor 61 and first threaded rod 62 fixed connection on deflector 5.

The rotating assembly comprises a third motor 8, the third motor 8 is fixedly connected in the working box 1, a second gear 81 is fixedly connected to the output end of the third motor 8, and the second gear 81 is matched with the first gear 63.

In the using process of the device, the placing bottle 4 with the sample can be placed in the placing hole 31 of the placing box 3, then the placing box 3 is placed in the working box 1 in a sliding mode, the opening is sealed through rotating a box door connected to the working box 1, furthermore, a UV disinfection lamp is installed in the inner cavity of the working box 1 and can kill bacteria in the air in the working box 1 when the box door is opened, wherein the placing bottle 4 and the bottle cover 41 are made of materials which cannot be penetrated by ultraviolet rays, such as dark common glass and the like, when the UV disinfection lamp fully disinfects the inside of the working box 1, the first threaded rod 62 and the second threaded rod 7 can be respectively driven by the second motor 71 and the first motor 61 to rotate so as to drive the sliding block 6 to slide in the working box 1, wherein the first threaded rod 62 can be driven by the first motor 61 to move in the front-back direction in the working box 1 in the rotating process of driving the sliding block 6, the second motor 71 drives the second threaded rod 7 to rotate and can drive the guide plate 5 and the slide block 6 to move in the left-right direction in the working box 1, after the slide block 6 moves to the position above the placing bottle 4 corresponding to nucleic acid to be extracted, the electromagnet 64 is started, the electromagnet 64 can generate suction force on the permanent magnet 42 fixedly connected to the bottle cap 41, so that the placing bottle 4 and the bottle cap 41 are adsorbed to the electromagnet 64, the electromagnet 64 is clamped into the bottle cap 41 to be attached to the permanent magnet 42, then the slide block 6 and the placing bottle 4 are moved to the position above the temporary placing support frame 9 through the second motor 71 and the first motor 61, the outer surface of the placing bottle 4 is attached to the inner wall of the limiting sleeve 91 at the moment, the first gear 63 is meshed with the second gear 81, the third motor 8 is started, the second gear 81 can be driven by the third motor 8 to rotate, so that the first gear 63 is driven to rotate, and the placing bottle 4 cannot rotate under the limiting of the limiting sleeve 91, so can open bottle lid 41 from placing bottle 4 top rotation, the lower extreme of placing bottle 4 moves downwards in step and inserts temporarily and puts in support frame 9, after bottle lid 41 and placing bottle 4 break away from completely, accessible second motor 71 and first motor 61 move slider 6 and bottle lid 41 open, then can carry out nucleic acid extraction to the sample of placing in bottle 4 through nucleic acid extractor 11, after the extraction is accomplished, slider 6 and bottle lid 41 are moved back to temporarily and are put support frame 9 top by second motor 71 and first motor 61, then electric telescopic handle 92 and third motor 8 work, electric telescopic handle 92 extends and puts support frame 9 and placing bottle 4 top movement in step, third motor 8 back drive first gear 63 rotates, so mutually support and can install bottle lid 41 rotation again on placing bottle 4 opening, after the installation, electric telescopic handle 92 contracts and resets, placing bottle 4 and slider 6 move back to its corresponding placing hole 31 top under first motor 61 and second motor 71 drive, electromagnet 64 stops work, can make placing bottle 4 and bottle lid 41 fall into corresponding to the dead weight of placing bottle 4 and accomplish the sample of this placing bottle 4 under the effect.

This device can be through holding box 3 will be deposited the bottle 4 of placing of sample and put into work box 1 in, and carry out sealed virus killing to work box 1, make the aseptic environment in the work box 1, then through first motor 61, second motor 71, electro-magnet 64, third motor 8, electric telescopic handle 92 and nucleic acid extractor 11 mutually support, move placing bottle 4, uncap, nucleic acid extraction and closing lid and move back to hold box 3 and originally place in the hole 31, thereby can avoid having now to lead to the sample to be contaminated to the not accurate problem of nucleic acid extraction result through the contact of nucleic acid quick extraction appearance in-process sample and air emergence of drawing nucleic acid.

Above, only be the embodiment of the preferred of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the design of the present invention, equivalent replacement or change should be included in the protection scope of the present invention.

Claims

1. Nucleic acid draws appearance fast, including work box (1), install nucleic acid extractor (11) in work box (1), its characterized in that still includes:

the storage box (3) is connected to the work box (1) in a sliding mode, a plurality of placing holes (31) are formed in the storage box (3), placing bottles (4) are placed in the placing holes (31), bottle caps (41) are connected to the placing bottles (4) in a threaded mode, hexagonal grooves are formed in the bottle caps (41), and permanent magnets (42) are fixedly connected to the hexagonal grooves;

the guide plate (5) is connected in the working box (1) in a sliding mode, a sliding block (6) is connected to the guide plate (5) in a sliding mode, the sliding block (6) is connected with a first gear (63) in a rotating mode, an electromagnet (64) is fixedly connected to the bottom of the first gear (63), and the electromagnet (64) is matched with the permanent magnet (42);

the electric telescopic rod (92) is fixedly connected in the work box (1), the telescopic end of the electric telescopic rod (92) is fixedly connected with a temporary placing support frame (9), the temporary placing support frame (9) is fixedly connected with a limiting sleeve (91), the temporary placing support frame (9) and the limiting sleeve (91) are matched with the placing bottle (4), and the nucleic acid extractor (11) is positioned above the limiting sleeve (91);

and the rotating assembly is used for driving the first gear (63) to rotate.

2. The instrument for rapidly extracting nucleic acid according to claim 1, wherein a second threaded rod (7) is rotatably connected in the work box (1), a connecting block (52) is fixedly connected to the bottom of the guide plate (5), the connecting block (52) is in threaded connection with the second threaded rod (7), a limiting sliding groove is formed in the work box (1), and two ends of the guide plate (5) are in sliding connection in the limiting sliding groove.

3. The nucleic acid rapid extraction instrument according to claim 2, characterized in that a second motor (71) is fixedly connected in the work box (1), and the output end of the second motor (71) is fixedly connected with the second threaded rod (7).

4. The instrument for rapidly extracting nucleic acid according to claim 1, wherein a support plate (51) is fixedly connected to the guide plate (5), a first threaded rod (62) is rotatably connected to the support plate (51), and the slide block (6) is threadedly connected to the first threaded rod (62).

5. The instrument for rapidly extracting nucleic acid according to claim 4, wherein the guide plate (5) is fixedly connected with a first motor (61), and the output end of the first motor (61) is fixedly connected with a first threaded rod (62).

6. The nucleic acid rapid extraction instrument according to claim 1, wherein the rotating assembly comprises a third motor (8), the third motor (8) is fixedly connected in the work box (1), a second gear (81) is fixedly connected to the output end of the third motor (8), and the second gear (81) is matched with the first gear (63).