CN215819755U - Device is deposited in freezing of umbilical cord blood sample that contains cord blood stem cell - Google Patents
Device is deposited in freezing of umbilical cord blood sample that contains cord blood stem cell Download PDFInfo
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- CN215819755U CN215819755U CN202122282415.0U CN202122282415U CN215819755U CN 215819755 U CN215819755 U CN 215819755U CN 202122282415 U CN202122282415 U CN 202122282415U CN 215819755 U CN215819755 U CN 215819755U
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- liquid nitrogen
- nitrogen storage
- freezing
- cord blood
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- 238000007710 freezing Methods 0.000 title claims abstract description 68
- 230000008014 freezing Effects 0.000 title claims abstract description 68
- 210000004700 fetal blood Anatomy 0.000 title claims abstract description 29
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 15
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 159
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 79
- 239000007788 liquid Substances 0.000 claims abstract description 73
- 238000000151 deposition Methods 0.000 claims description 6
- 210000004369 blood Anatomy 0.000 abstract description 14
- 239000008280 blood Substances 0.000 abstract description 14
- 239000000523 sample Substances 0.000 description 19
- 210000004027 cell Anatomy 0.000 description 5
- 238000005138 cryopreservation Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000002659 cell therapy Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- FGRBYDKOBBBPOI-UHFFFAOYSA-N 10,10-dioxo-2-[4-(N-phenylanilino)phenyl]thioxanthen-9-one Chemical compound O=C1c2ccccc2S(=O)(=O)c2ccc(cc12)-c1ccc(cc1)N(c1ccccc1)c1ccccc1 FGRBYDKOBBBPOI-UHFFFAOYSA-N 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000012606 in vitro cell culture Methods 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The utility model discloses a freezing and storing device for an umbilical cord blood sample containing umbilical cord blood stem cells, which comprises a carrying vehicle body, wherein one side inside the carrying vehicle body is provided with a liquid nitrogen storage chamber, the other side inside the carrying vehicle body is provided with four freezing and storing chambers, the four freezing and storing chambers are uniformly distributed, a liquid nitrogen storage tank is arranged inside the liquid nitrogen storage chamber, one side of the inner wall of the liquid nitrogen storage chamber is fixedly connected with an air guide pipe, one end of the air guide pipe extends into one of the freezing and storing chambers, the number of the liquid nitrogen storage tanks is two, the output ends of the two liquid nitrogen storage tanks are communicated with the air guide pipe, and a control valve is fixedly connected between the output ends of the two liquid nitrogen storage tanks and the air guide pipe. According to the utility model, the four mutually communicated freezing chambers are arranged, and the air guide holes are controlled to be opened and closed by the plugging plate, so that the corresponding freezing chambers can be isolated, a large amount of low-temperature nitrogen can be prevented from escaping when a blood sample is extracted, and the loss of liquid nitrogen in the device can be reduced.
Description
Technical Field
The utility model relates to the field of blood sample cryopreservation devices, in particular to a cryopreservation device for an umbilical cord blood sample containing umbilical cord blood stem cells.
Background
With the development of biological technologies, cell therapy is rapidly developing and increasingly accepted worldwide. The basis of cell therapy is the harvesting and storage of viable cells. In addition, in vitro culture of cells has also been widely used in various fields of biological research. In the in vitro cell culture work, in order to preserve cells and enable the cells to have biological activity for a long time, the freezing and recovery of the cells become a crucial link. Biological samples such as umbilical cord blood, stem cells and the like need to be stored at low temperature through a freezing device.
Current blood sample cryopreserved device on the market is inside only to be provided with one and cryopreserved room, when extracting the blood sample, opens and cryopreserved room top sealed lid after can make whole cryopreserved room expose outside, cryopreserved indoor portion's low temperature nitrogen gas can borrow a large amount of effluviums of machine, leads to the inside liquid nitrogen excessive consumption of device.
Therefore, it is necessary to invent a cryopreservation apparatus for cord blood sample containing cord blood stem cells to solve the above problems.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a freezing device for an umbilical cord blood sample containing umbilical cord blood stem cells, which aims to solve the problems that the conventional blood sample freezing device on the market is generally only internally provided with one freezing chamber, when the blood sample is extracted, the whole freezing chamber is exposed after a sealing cover at the top of the freezing chamber is opened, and low-temperature nitrogen in the freezing chamber can escape from the freezing chamber by virtue of a machine in a large amount, so that liquid nitrogen in the device is excessively consumed.
In order to achieve the above purpose, the utility model provides the following technical scheme: a freezing device for an umbilical cord blood sample containing umbilical cord blood stem cells comprises a carrying vehicle body, wherein one side inside the carrying vehicle body is provided with a liquid nitrogen storage chamber, the other side inside the carrying vehicle body is provided with four freezing chambers, the four freezing chambers are uniformly distributed, a liquid nitrogen storage tank is arranged inside the liquid nitrogen storage chamber, one side of the inner wall of the liquid nitrogen storage chamber is fixedly connected with an air guide tube, one end of the air guide tube extends into one freezing chamber, the number of the liquid nitrogen storage tanks is two, the output ends of the two liquid nitrogen storage tanks are communicated with the air guide tube, a control valve is fixedly connected between the output ends of the two liquid nitrogen storage tanks and the air guide tube, an air guide hole is formed between every two adjacent freezing chambers, a plugging plate is arranged inside the air guide hole, the middle part of the plugging plate is fixedly connected with a rotating shaft, one end of the rotating shaft penetrates through the bottom of the air guide hole and is rotatably connected with the carrying vehicle body, the pivot other end runs through air guide hole top and extends to delivery automobile body top, the one end fixedly connected with carousel that the pivot extends to delivery automobile body top.
Preferably, liquid nitrogen storage room bottom fixedly connected with fixing base, the liquid nitrogen storage tank sets up in the fixing base top, liquid nitrogen storage room inner wall one side fixedly connected with buckle, liquid nitrogen storage tank and buckle looks joint, buckle quantity sets up to two, two be equipped with the magic between the buckle and paste the bandage.
Preferably, one side of the liquid nitrogen storage chamber is provided with a cabinet door, the cabinet door is hinged to one side of the carrying vehicle body, the top of the freezing storage chamber is provided with a top cover, and the top cover is hinged to the top of the carrying vehicle body.
Preferably, four it all is equipped with the freezing frame to freeze and deposits indoor portion, the inside rotation of freezing frame is connected with the fixed axle, the fixed cover in fixed axle surface has connect the freezing dish of depositing, the freezing dish quantity sets up to a plurality ofly, and is a plurality of the freezing dish of depositing is linear array and distributes.
Preferably, one side of the freezing and depositing frame is provided with a taking and placing notch, two fixed hanging lugs fixedly connected with the two sides of the top of the freezing and depositing frame are respectively connected with the two sides of the top of the freezing and depositing chamber in a clamping manner.
Preferably, a cart handle is fixedly connected to one side of the carrying cart body, and universal self-locking rollers are fixedly connected to four corners of the bottom of the carrying cart body.
In the technical scheme, the utility model provides the following technical effects and advantages:
1. the freezing area is divided into four mutually communicated freezing chambers, and the air guide holes are controlled to be opened and closed by the plugging plates, so that the corresponding freezing chambers can be isolated, a large amount of low-temperature nitrogen can be prevented from escaping when a blood sample is extracted, and the loss of liquid nitrogen in the device can be reduced;
2. through being provided with two liquid nitrogen storage tanks in liquid nitrogen storage chamber inside, only one of them liquid nitrogen storage tank is in using, and after one of them liquid nitrogen storage tank used up, close it through the last control valve to dock unused liquid nitrogen storage tank and air duct through another control valve, when guaranteeing device normal operating, can make things convenient for the staff to change the liquid nitrogen storage tank that has used up.
Drawings
In order to more clearly illustrate the embodiments of the present application or technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings can be obtained by those skilled in the art according to the drawings.
FIG. 1 is a schematic overall structure diagram of a first perspective of the present invention;
FIG. 2 is a schematic overall structure diagram of a second perspective of the present invention;
FIG. 3 is a partial sectional view of the present invention;
FIG. 4 is a schematic view of the connection structure of the freezing rack and the freezing chamber according to the present invention;
FIG. 5 is a schematic structural diagram of the cryopreservation rack of the present invention.
Description of reference numerals:
1. a carrier vehicle body; 2. a liquid nitrogen storage chamber; 3. freezing and storing in a room; 4. a liquid nitrogen storage tank; 5. an air duct; 6. a control valve; 7. an air vent; 8. a plugging plate; 9. a rotating shaft; 10. a turntable; 11. a fixed seat; 12. buckling; 13. a magic tape; 14. a cabinet door; 15. a top cover; 16. freezing and storing the shelves; 17. a fixed shaft; 18. freezing and storing the disc; 19. a notch is taken and placed; 20. fixing the hangers; 21. a cart handle; 22. universal auto-lock gyro wheel.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The utility model provides a freezing and storing device for an umbilical cord blood sample containing umbilical cord blood stem cells, which comprises a carrier vehicle body 1, wherein one side inside the carrier vehicle body 1 is provided with a liquid nitrogen storage chamber 2, the other side inside the carrier vehicle body 1 is provided with a freezing and storing chamber 3, the number of the freezing and storing chambers 3 is four, the four freezing and storing chambers 3 are uniformly distributed, the inside of the liquid nitrogen storage chamber 2 is provided with a liquid nitrogen storage tank 4, one side of the inner wall of the liquid nitrogen storage chamber 2 is fixedly connected with an air duct 5, one end of the air duct 5 extends into one of the freezing and storing chambers 3, the number of the liquid nitrogen storage tanks 4 is two, the output ends of the two liquid nitrogen storage tanks 4 are both communicated with the air duct 5, a control valve 6 is fixedly connected between the output ends of the two liquid nitrogen storage tanks 4 and the air duct 5, and an air guide hole 7 is arranged between every two adjacent freezing and storing chambers 3, the inside shutoff board 8 that is equipped with of air guide hole 7, 8 middle part fixedly connected with pivots 9 of shutoff board, 9 one end of pivot run through air guide hole 7 bottoms and rotate with delivery automobile body 1 and be connected, the 9 other ends of pivot run through air guide hole 7 tops and extend to 1 top of delivery automobile body, pivot 9 extends to the one end fixedly connected with carousel 10 at 1 top of delivery automobile body.
Further, in above-mentioned technical scheme, 2 bottom fixedly connected with fixing bases 11 of liquid nitrogen apotheca, liquid nitrogen storage tank 4 sets up in fixing base 11 top, 2 inner wall one side fixedly connected with buckles 12 of liquid nitrogen apotheca, liquid nitrogen storage tank 4 and buckle 12 looks joint, buckle 12 quantity sets up to two be equipped with magic subsides bandage 13 between the buckle 12, when installing liquid nitrogen storage tank 4, place liquid nitrogen storage tank 4 bottom in fixing base 11 top earlier, carry out the joint with liquid nitrogen storage tank 4 and buckle 12 after that, realize the preliminary fixed to liquid nitrogen storage tank 4, the rethread magic subsides bandage 13 ties up liquid nitrogen storage tank 4 at last, accomplishes the further fixed to liquid nitrogen storage tank 4.
Further, in the above technical scheme, a cabinet door 14 is arranged on one side of the liquid nitrogen storage chamber 2, the cabinet door 14 is hinged to one side of the carrier vehicle body 1, four top covers 15 are arranged on the tops of the freezing chambers 3, the top covers 15 are hinged to the top of the carrier vehicle body 1, the liquid nitrogen storage tank 4 can be loaded and unloaded through the cabinet door 14, and the freezing rack 16 can be placed and taken through the top covers 15.
Further, in above-mentioned technical scheme, four it all is equipped with the cryopreserved frame 16 to cryopreserve room 3 inside, cryopreserved frame 16 internal rotation is connected with fixed axle 17, the fixed cover in fixed axle 17 surface has connect cryopreserved dish 18, cryopreserved dish 18 quantity sets up to a plurality ofly, and is a plurality of cryopreserved dish 18 is linear array and distributes, drives cryopreserved dish 18 through rotating fixed axle 17 and rotates, can realize the switching of the blood sample on the cryopreserved dish 18, is convenient for extract the blood sample.
Further, in above-mentioned technical scheme, it gets and puts notch 19 to have seted up on one side of freezing frame 16, freezing frame 16 top both sides equal fixedly connected with fixed hangers 20, two fixed hangers 20 respectively with freeze room 3 top both sides looks joint, fixed hangers 20 set up conveniently will freeze frame 16 joint and spacing in freezing room 3.
Further, in above-mentioned technical scheme, 1 one side fixedly connected with of delivery automobile body shallow handle 21, the equal fixedly connected with universal auto-lock gyro wheel 22 in 1 bottom four corners of delivery automobile body, staff's accessible shallow handle 21 and universal auto-lock gyro wheel 22 remove the device is whole, are convenient for shift the transportation to the blood sample.
This practical theory of operation:
referring to the attached drawings 1-5 of the specification, when the utility model is used, a top cover 15 is opened, a freezing frame 16 storing a blood sample is placed in a freezing chamber 3, then the top cover 15 is closed, a control valve 6 on one of liquid nitrogen storage tanks 4 is opened, low-temperature nitrogen in the liquid nitrogen storage tank 4 enters one of the freezing chambers 3 through an air duct 5, a rotating shaft 9 is driven to rotate through a rotating disc 10, a plugging plate 8 on the rotating shaft 9 rotates in the air guide hole 7 to realize the opening and closing control of the air guide hole 7, the air guide hole 7 is opened through the plugging plate 8, the four freezing chambers 3 are communicated with each other through the air guide hole 7, the low-temperature nitrogen can flow among the four freezing chambers 3, when the blood sample in one freezing chamber 3 needs to be extracted, the air guide holes 7 on the two adjacent freezing chambers 3 are closed through the plugging plate 8 to isolate the freezing chambers 3, the top cover 15 is opened and the blood sample is extracted, the freezing area is divided into four mutually communicated freezing chambers 3, the air guide holes 7 are controlled to be opened and closed through the plugging plates 8, the corresponding freezing chambers 3 can be isolated, low-temperature nitrogen can be prevented from escaping in large quantity when the blood sample is extracted, and the loss of liquid nitrogen in the device can be reduced;
referring to the attached figures 1-5 of the specification, when the device is used, two liquid nitrogen storage tanks 4 are arranged in a liquid nitrogen storage chamber 2, only one of the liquid nitrogen storage tanks 4 is in use, when one of the liquid nitrogen storage tanks 4 is used up, the liquid nitrogen storage tank is closed through a control valve 6 on the liquid nitrogen storage tank, and the unused liquid nitrogen storage tank 4 is in butt joint with an air duct 5 through the other control valve 6, so that the device can be ensured to normally operate, and meanwhile, the used liquid nitrogen storage tank 4 can be conveniently replaced by a worker.
The standard parts used in the utility model can be purchased from the market, the special-shaped parts can be customized according to the description of the specification and the accompanying drawings, the specific connection mode of each part adopts conventional means such as bolts, rivets, welding and the like mature in the prior art, the machines, the parts and equipment adopt conventional models in the prior art, and the circuit connection adopts the conventional connection mode in the prior art, so that the detailed description is omitted.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes in the embodiments and/or modifications of the utility model can be made, and equivalents and modifications of some features of the utility model can be made without departing from the spirit and scope of the utility model.
Claims (6)
1. A device for cryopreserving a cord blood sample containing cord blood stem cells comprises a carrier vehicle body (1), and is characterized in that: the device is characterized in that liquid nitrogen storage chambers (2) are arranged on one side inside the carrier vehicle body (1), freezing storage chambers (3) are arranged on the other side inside the carrier vehicle body (1), the number of the freezing storage chambers (3) is four, the four freezing storage chambers (3) are uniformly distributed, liquid nitrogen storage tanks (4) are arranged inside the liquid nitrogen storage chambers (2), air guide pipes (5) are fixedly connected to one side of the inner wall of each liquid nitrogen storage chamber (2), one ends of the air guide pipes (5) extend into one of the freezing storage chambers (3), the number of the liquid nitrogen storage tanks (4) is two, the output ends of the two liquid nitrogen storage tanks (4) are communicated with the air guide pipes (5), control valves (6) are fixedly connected between the output ends of the two liquid nitrogen storage tanks (4) and the air guide pipes (5), and air guide holes (7) are formed between the two adjacent freezing storage chambers (3), air guide hole (7) inside is equipped with shutoff board (8), shutoff board (8) middle part fixedly connected with pivot (9), pivot (9) one end runs through air guide hole (7) bottom and rotates with delivery automobile body (1) to be connected, pivot (9) other end runs through air guide hole (7) top and extends to delivery automobile body (1) top, pivot (9) extend to one end fixedly connected with carousel (10) at delivery automobile body (1) top.
2. The apparatus for cryopreserving a cord blood sample containing cord blood stem cells according to claim 1, wherein: liquid nitrogen storage chamber (2) bottom fixedly connected with fixing base (11), liquid nitrogen storage tank (4) set up in fixing base (11) top, liquid nitrogen storage chamber (2) inner wall one side fixedly connected with buckle (12), liquid nitrogen storage tank (4) and buckle (12) looks joint, buckle (12) quantity sets up to two, two be equipped with magic subsides bandage (13) between buckle (12).
3. The apparatus for cryopreserving a cord blood sample containing cord blood stem cells according to claim 1, wherein: liquid nitrogen storage chamber (2) one side is equipped with cabinet door (14), cabinet door (14) and the articulated setting in delivery automobile body (1) one side, four it all is equipped with top cap (15) to freeze storage chamber (3) top, top cap (15) and the articulated setting in delivery automobile body (1) top.
4. The apparatus for cryopreserving a cord blood sample containing cord blood stem cells according to claim 1, wherein: four it all is equipped with freezes deposits frame (16) to freeze and deposit room (3) inside, it is connected with fixed axle (17) to freeze to deposit frame (16) inside rotation, fixed axle (17) surface cover has connect freezes deposits dish (18), it sets up to a plurality ofly to freeze deposits dish (18) quantity, and is a plurality of it is linear array to freeze deposits dish (18) and distributes.
5. The apparatus for cryopreserving a cord blood sample containing cord blood stem cells according to claim 4, wherein: freezing frame (16) one side of depositing and having seted up and put notch (19), freezing frame (16) top both sides equal fixedly connected with fixed hangers (20), two fixed hangers (20) respectively with freeze room (3) top both sides looks joint.
6. The apparatus for cryopreserving a cord blood sample containing cord blood stem cells according to claim 1, wherein: one side of the carrying vehicle body (1) is fixedly connected with a trolley handle (21), and four corners of the bottom of the carrying vehicle body (1) are fixedly connected with universal self-locking rollers (22).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122282415.0U CN215819755U (en) | 2021-09-22 | 2021-09-22 | Device is deposited in freezing of umbilical cord blood sample that contains cord blood stem cell |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122282415.0U CN215819755U (en) | 2021-09-22 | 2021-09-22 | Device is deposited in freezing of umbilical cord blood sample that contains cord blood stem cell |
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| Publication Number | Publication Date |
|---|---|
| CN215819755U true CN215819755U (en) | 2022-02-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202122282415.0U Active CN215819755U (en) | 2021-09-22 | 2021-09-22 | Device is deposited in freezing of umbilical cord blood sample that contains cord blood stem cell |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115176794A (en) * | 2022-05-30 | 2022-10-14 | 五心生物科技(福建)有限公司 | Freezing storage device for low-temperature storage of umbilical cord blood stem cells |
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2021
- 2021-09-22 CN CN202122282415.0U patent/CN215819755U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115176794A (en) * | 2022-05-30 | 2022-10-14 | 五心生物科技(福建)有限公司 | Freezing storage device for low-temperature storage of umbilical cord blood stem cells |
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Address after: Room 526, 5th Floor, Building 1, No. 6 Kangye Road, Zhujiajiao Town, Qingpu District, Shanghai, 201713 Patentee after: Shanghai Wuxin Medical Technology Group Co.,Ltd. Country or region after: China Address before: 201109 room 218, No. 2, No. 3399, Yuanjiang Road, Minhang District, Shanghai Patentee before: Shanghai Wuxin Hospital Management Co.,Ltd. Country or region before: China |