CN217884908U - Cryopreservation device for cord blood hematopoietic stem cells - Google Patents

Cryopreservation device for cord blood hematopoietic stem cells Download PDF

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Publication number
CN217884908U
CN217884908U CN202222385732.XU CN202222385732U CN217884908U CN 217884908 U CN217884908 U CN 217884908U CN 202222385732 U CN202222385732 U CN 202222385732U CN 217884908 U CN217884908 U CN 217884908U
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Prior art keywords
freezing
hematopoietic stem
vacuum
movably connected
box
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CN202222385732.XU
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Chinese (zh)
Inventor
程乐杰
郝建峰
李菁菁
周倩茜
马静
陈慧
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Lejie Hainan Biotechnology Co ltd
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Lejie Hainan Biotechnology Co ltd
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Abstract

The utility model relates to a navel blood freezes deposits technical field, specifically is a device is deposited in freezing of navel blood hematopoietic stem cell, the power distribution box comprises a box body, the top swing joint of box has elevating system, the side swing joint of box has the handle, the one end swing joint of handle has the pivot, the middle part difference swing joint of pivot has vacuum storehouse and freezes deposits the storehouse, the inner wall swing joint that freezes the storehouse has the support, and the device is deposited in freezing after the improvement, through constituting the screw drive structure between threaded rod and the vacuum seal piece and make to freeze and deposit the device and can have good leakproofness, avoid freezing the temperature loss in depositing the device, reduced the consumption of liquid nitrogen, practiced thrift the cost, pivot, vacuum storehouse and freeze and deposit between the storehouse coaxial be convenient for find target navel blood hematopoietic stem cell through the pivot fast, annular equidistance distributes between the box and make placing that navel blood hematopoietic stem cell can be steady safety freeze and deposit the storehouse in, avoid freezing and deposit the collision between the box, lead to rupture and pollute.

Description

Cryopreservation device for umbilical blood hematopoietic stem cells
Technical Field
The utility model relates to a navel blood freezes deposits technical field, specifically is a navel blood hematopoietic stem cell freezes deposits device.
Background
The umbilical cord blood contains a large amount of stem cells, the stem cells are life seeds, the umbilical cord blood is differentiated into various cells in a human body and bears various fruits, namely blood cells, nerve cells, bone cells and the like, the characteristics and the number of the cells can be maintained through differentiation, and the umbilical cord blood is further differentiated into various tissue cells, so that the umbilical cord blood plays a positive role in tissue repair and the like, contains abundant hematopoietic stem cells, can reconstruct the hematopoietic system and the immune system of the human body, and can be used for hematopoietic stem cell transplantation and treatment of the blood system, the immune system, genetic diseases and genetic diseases.
Human umbilical cord blood stem cells are usually stored in a low-temperature refrigerator or a liquid nitrogen tank at-85 ℃ or-196 ℃ according to different storage years, at present, a freezing storage box is generally opened at the top, and collection bags containing the umbilical cord blood stem cells are sequentially placed in the storage box from top to bottom, so a freezing storage device containing liquid nitrogen is usually adopted for long-time storage.
The prior patent (publication number: CN 215819755U) discloses a freezing device for umbilical cord blood samples containing umbilical cord blood stem cells, which comprises a carrying vehicle body, wherein a liquid nitrogen storage chamber is arranged on one side inside the carrying vehicle body, a freezing chamber is arranged on the other side inside the carrying vehicle body, the number of the freezing chambers is four, the freezing chambers are uniformly distributed, a liquid nitrogen storage tank is arranged inside the liquid nitrogen storage chamber, an air guide tube is fixedly connected to one side of the inner wall of the liquid nitrogen storage chamber, one end of the air guide tube extends to one of the freezing chambers, the number of the liquid nitrogen storage tanks is two, the output ends of the liquid nitrogen storage tanks are communicated with the air guide tube, and a control valve is fixedly connected between the output ends of the liquid nitrogen storage tanks and the air guide tube. The utility model discloses a set up four freezing rooms that communicate each other to carry out on-off control through the shutoff board to the air guide hole, can realize freezing the isolation of depositing the room correspondingly, low temperature nitrogen gas escapes in a large number when can avoiding drawing the blood specimen, is favorable to reducing the inside liquid nitrogen loss volume of device. The inventor finds that the prior art has the following problems in the process of realizing the utility model: the traditional cryopreservation device is inconvenient in placing and extracting hematopoietic stem cells, and causes a large amount of liquid nitrogen loss, resource waste and cost increase.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a device is deposited to freezing of navel blood hematopoietic stem cell to solve the problem that provides among the above-mentioned background art. In order to achieve the above object, the utility model provides a following technical scheme: the device for freezing and storing the umbilical cord blood hematopoietic stem cells comprises a box body, wherein the top of the box body is movably connected with a lifting mechanism, the side surface of the box body is movably connected with a handle, one end of the handle is movably connected with a rotating shaft, the middle part of the rotating shaft is respectively and movably connected with a vacuum bin and a freezing bin, the inner wall of the freezing bin is movably connected with a support, the outer side of the support is movably connected with sixteen freezing boxes, the bottom of the freezing bin is movably connected with a vacuum conveying pipe, and one end of the vacuum conveying pipe is movably connected with a liquid nitrogen tank;
elevating system includes the top swing joint of box and has the threaded rod, the middle part swing joint of threaded rod has the vacuum seal piece, the middle part swing joint of vacuum seal piece has the thing clamp of getting.
Further preferably, the top of the box body is provided with an opening matched with the vacuum sealing block.
Further preferably, a threaded transmission structure is formed between the threaded rod and the vacuum sealing block.
Further preferably, the rotating shaft, the vacuum bin and the freezing and storing bin are coaxial.
Further preferably, the top of the bracket is provided with an elastic buckle.
Further preferably, sixteen freezing storage boxes are annularly and equidistantly distributed by taking the central axis of the rotating shaft as a circle center.
Compared with the prior art, the beneficial effects of the utility model are that:
the utility model discloses in, it makes the taking and putting of cord blood hematopoietic stem cell convenient safety to set up the opening through the top of box, constitutes the screw thread transmission structure between threaded rod and the vacuum seal piece and makes to freeze and deposit the device and can have good leakproofness, avoids freezing the temperature loss of depositing in the device, has reduced the consumption of liquid nitrogen, has practiced thrift the cost.
The utility model discloses in, through pivot, vacuum storehouse and freeze between the storehouse coaxial be convenient for find target cord blood hematopoietic stem cell through the pivot fast, the top of support is equipped with elastic buckle and makes the centre gripping that the box can be stabilized of freezing deposit in freezing the storehouse, is difficult for dropping, sixteen freeze between the box annular equidistance distribute make cord blood hematopoietic stem cell can be steady safe place freeze in depositing the storehouse, avoid freezing to deposit and bump between the box, lead to breaking and polluting.
Drawings
FIG. 1 is a front view of the full-section structure of the present invention;
FIG. 2 is a schematic view of a side view full-section structure of the present invention;
fig. 3 is a schematic view of the front view structure of the bracket of the present invention.
In the figure: 1. a box body; 2. a lifting mechanism; 201. a threaded rod; 202. a vacuum seal block; 203. fetching clips; 3. a handle; 4. a rotating shaft; 5. a vacuum bin; 6. freezing and storing in a bin; 7. a support; 8. freezing and storing the box; 9. a vacuum delivery pipe; 10. and a liquid nitrogen tank.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by the staff of ordinary skill in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1 to 3, the present invention provides a technical solution: a cryopreservation device for cord blood hematopoietic stem cells comprises a box body 1, wherein the top of the box body 1 is movably connected with a lifting mechanism 2, the side surface of the box body 1 is movably connected with a handle 3, one end of the handle 3 is movably connected with a rotating shaft 4, the middle part of the rotating shaft 4 is respectively movably connected with a vacuum bin 5 and a cryopreservation bin 6, the inner wall of the cryopreservation bin 6 is movably connected with a support 7, the outer side of the support 7 is movably connected with sixteen cryopreservation boxes 8, the bottom of the cryopreservation bin 6 is movably connected with a vacuum conveying pipe 9, and one end of the vacuum conveying pipe 9 is movably connected with a liquid nitrogen tank 10;
the lifting mechanism 2 comprises a threaded rod 201 movably connected to the top of the box body 1, a vacuum sealing block 202 is movably connected to the middle of the threaded rod 201, and a fetching clamp 203 is movably connected to the middle of the vacuum sealing block 202.
In this embodiment, as shown in fig. 1, an opening adapted to the vacuum sealing block 202 is formed at the top of the box body 1; it should be noted that the top of the box body 1 is provided with an opening matched with the vacuum sealing block 202, so that the cord blood hematopoietic stem cells can be conveniently and safely taken and placed.
In this embodiment, as shown in fig. 1, a threaded transmission structure is formed between the threaded rod 201 and the vacuum sealing block 202; it should be noted that the threaded transmission structure formed between the threaded rod 201 and the vacuum sealing block 202 enables the cryopreservation device to have good sealing performance, avoids temperature loss in the cryopreservation device, reduces consumption of liquid nitrogen, and saves cost.
In this embodiment, as shown in fig. 2, the rotating shaft 4, the vacuum chamber 5 and the freezing chamber 6 are coaxial; it should be noted that the coaxial shaft 4, the vacuum chamber 5 and the freezing chamber 6 facilitate the rapid finding of the target cord blood hematopoietic stem cells through the shaft 4.
In this embodiment, as shown in fig. 1, the top of the bracket 7 is provided with an elastic buckle; it should be noted that the top of the bracket 7 is provided with an elastic buckle to stably clamp the cryopreservation box 8 in the cryopreservation chamber 6, so that the cryopreservation box is not easy to fall off.
In this embodiment, as shown in fig. 1, sixteen cryopreservation boxes 8 are annularly and equidistantly distributed with the central axis of the rotating shaft 4 as the center of a circle; it should be noted that, through sixteen cryopreserved boxes 8 with the axis of pivot 4 as the centre of a circle annular equidistance distribution make cord blood hematopoietic stem cells can steadily safe place in cryopreserved storehouse 6 between the cryopreserved box 8, avoid colliding between the cryopreserved box 8, lead to breaking and polluting.
The utility model discloses a use method and advantage: when the cryopreservation device for cord blood hematopoietic stem cells is used, the working process is as follows:
as shown in fig. 1, 2 and 3, firstly the vacuum sealing block 202 is moved out of the box body 1 through the threaded rod 201, the freezing box 8 is placed on the support 7 through the fetching clamp 203 and is fixed in the freezing bin 6 through the elastic buckle, the vacuum sealing block 202 and the freezing bin 6 are tightly closed in the same way, the liquid nitrogen tank 10 conveys the liquid nitrogen into the freezing bin 6 through the vacuum conveying pipe 9, and the vacuum bin 5 outside the freezing bin 6 has a good heat preservation effect on the freezing bin 6.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It should be understood by those skilled in the art that the present invention is not limited by the above embodiments, and the description in the above embodiments and the description is only preferred examples of the present invention, and is not intended to limit the present invention, and that there may be various changes and modifications without departing from the spirit and scope of the present invention, and these changes and modifications all fall within the scope of the claimed invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (6)

1. The utility model provides a device is deposited to freezing of navel blood hematopoietic stem cell, includes box (1), its characterized in that: the freezing and storing device is characterized in that the top of the box body (1) is movably connected with a lifting mechanism (2), the side face of the box body (1) is movably connected with a handle (3), one end of the handle (3) is movably connected with a rotating shaft (4), the middle part of the rotating shaft (4) is respectively movably connected with a vacuum bin (5) and a freezing and storing bin (6), the inner wall of the freezing and storing bin (6) is movably connected with a support (7), the outer side of the support (7) is movably connected with sixteen freezing and storing boxes (8), the bottom of the freezing and storing bin (6) is movably connected with a vacuum conveying pipe (9), and one end of the vacuum conveying pipe (9) is movably connected with a liquid nitrogen tank (10);
elevating system (2) have threaded rod (201) including the top swing joint of box (1), the middle part swing joint of threaded rod (201) has vacuum seal piece (202), the middle part swing joint of vacuum seal piece (202) gets thing clamp (203).
2. The cryopreservation apparatus for umbilical cord blood hematopoietic stem cells according to claim 1, wherein: the top of the box body (1) is provided with an opening matched with the vacuum sealing block (202).
3. The cryopreservation apparatus for umbilical cord blood hematopoietic stem cells according to claim 1, wherein: and a thread transmission structure is formed between the threaded rod (201) and the vacuum sealing block (202).
4. The cryopreservation apparatus for umbilical cord blood hematopoietic stem cells according to claim 1, wherein: the rotating shaft (4), the vacuum bin (5) and the freezing storage bin (6) are coaxial.
5. The cryopreservation apparatus for umbilical cord blood hematopoietic stem cells according to claim 1, wherein: the top of the bracket (7) is provided with an elastic buckle.
6. The cryopreservation apparatus for umbilical cord blood hematopoietic stem cells according to claim 1, wherein: sixteen freezing storage boxes (8) are distributed in an annular and equidistant mode by taking the central axis of the rotating shaft (4) as the center of a circle.
CN202222385732.XU 2022-09-08 2022-09-08 Cryopreservation device for cord blood hematopoietic stem cells Active CN217884908U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222385732.XU CN217884908U (en) 2022-09-08 2022-09-08 Cryopreservation device for cord blood hematopoietic stem cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222385732.XU CN217884908U (en) 2022-09-08 2022-09-08 Cryopreservation device for cord blood hematopoietic stem cells

Publications (1)

Publication Number Publication Date
CN217884908U true CN217884908U (en) 2022-11-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222385732.XU Active CN217884908U (en) 2022-09-08 2022-09-08 Cryopreservation device for cord blood hematopoietic stem cells

Country Status (1)

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CN (1) CN217884908U (en)

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