CN212441302U

CN212441302U - Vehicle-mounted positive pressure nucleic acid detection reagent preparation system

Info

Publication number: CN212441302U
Application number: CN202020951828.6U
Authority: CN
Inventors: 谢孝民; 李丹; 熊磊; 谢正华; 陈才夫; 袁庆明; 王兆松
Original assignee: Shanghai 3D Medicines Co Ltd
Current assignee: Shanghai 3D Medicines Co Ltd
Priority date: 2020-05-29
Filing date: 2020-05-29
Publication date: 2021-02-02
Anticipated expiration: 2030-05-29

Abstract

The utility model relates to a system is prepared to on-vehicle malleation nucleic acid detect reagent, include and prepare the module by the buffering module and the reagent of first airtight door mutual isolation, through the whole establishment of malleation laboratory that will be used for nucleic acid detect reagent to prepare on vehicle-mounted platform, can be at any time as required fast migration, arrange in a flexible way to the area of needs most, can effectively improve hot spot area nucleic acid detect reagent configuration ability through reasonable allotment, promote nucleic acid detection efficiency, need not the repeated construction malleation laboratory simultaneously, avoid the wasting of resources.

Description

Vehicle-mounted positive pressure nucleic acid detection reagent preparation system

Technical Field

The utility model relates to a pathogen detection equipment technical field especially relates to a system is prepared to on-vehicle malleation nucleic acid detect reagent.

Background

The novel coronavirus pathogen is an airborne virus pathogen with the characteristics of strong infectivity and strong pathogenicity, and often presents explosive diffusion infection in community people, thereby forming a very serious threat to the life health of people.

Because there is no specific medicine for pneumonia and other diseases caused by novel coronavirus pathogen at present, the early discovery and isolation of infected people become the most effective means for preventing and treating novel coronavirus pathogen, and the nucleic acid detection method which is most commonly used at present is a screening means which is acknowledged to be high in accuracy and reliable in result.

The nucleic acid amplification detection comprises the preparation of a reaction reagent, sample treatment and amplification, and the reaction reagent is easily polluted by nucleic acid to cause false positive in detection, so that the result is misjudged. Therefore, the reagent preparation room needs to control the air flow direction through pressure difference, and a positive pressure laboratory is used for ensuring that the reagent preparation environment is not polluted by the external environment. For a sudden epidemic situation, a large number of patients need to perform nucleic acid detection in a short time, and at the moment, the number of positive pressure laboratories in a hot spot area is insufficient, the configuration capacity of a nucleic acid detection reagent cannot meet the requirement, and the nucleic acid detection efficiency is reduced.

SUMMERY OF THE UTILITY MODEL

For solving prior art's is not enough, the utility model provides a system is prepared to on-vehicle malleation nucleic acid detect reagent through the whole establishment of malleation laboratory that will be used for nucleic acid detect reagent to prepare on vehicle platform, provides the nucleic acid detect reagent preparation ability that can the quick travel disposed, can effectively improve hot spot area nucleic acid detect reagent configuration ability through reasonable allotment, promotes nucleic acid detection efficiency, need not the repeated construction malleation laboratory simultaneously, avoids the wasting of resources.

In order to achieve the above object, the utility model discloses the technical scheme who adopts includes:

a vehicle-mounted positive pressure nucleic acid detection reagent preparation system is characterized by comprising a buffer module and a reagent preparation module which are mutually isolated by a first airtight door;

the buffer module comprises first positive pressure equipment, a vehicle-mounted power supply device, a first airtight door connected with the reagent preparation module and a second airtight door connected with the external environment;

reagent preparation module includes second malleation equipment, reagent storage device, places reagent and prepares operation panel and the electrical connection of instrument the distribution equipment of on-vehicle power supply unit and/or outside power supply, just reagent preparation module lateral wall is provided with an airtight pass-through window of connecting the external environment at least.

Further, the first airtight door and the second airtight door are rotating doors which are opened towards one side of the buffer module.

Further, the first positive pressure device provides a higher stable ambient pressure value than the second positive pressure device.

Further, the reagent storage apparatus includes a freezing refrigerator of-20 ℃ and a refrigerating refrigerator of 4 ℃.

Further, the reagent preparation module also comprises a hand washing sink, a waste liquid tank and a waste garbage can.

Further, the buffer module and the reagent preparation module are also provided with an ultraviolet disinfection lamp and an air interchanger.

Further, an ultraviolet disinfection lamp is arranged in the airtight transfer window.

Further, the external power supply comprises a mains interface and/or a photovoltaic power supply arranged on the top outside the system.

Further, the system also comprises an independent air conditioning device.

The utility model has the advantages that:

adopt on-vehicle malleation nucleic acid detect reagent preparation system has realized establishing the complete malleation laboratory that has buffer module on vehicle-mounted platform, can accomplish the whole flows of nucleic acid detect reagent configuration in this system, make nucleic acid detect reagent configuration ability break away from the constraint of fixed laboratory, can be at any time as required fast movement, arrange in a flexible way to the area of needs most, make full use of current nucleic acid detect reagent configuration ability, reduce interim malleation laboratory construction pressure, be the ideal solution of a large amount of detection demands of coping emergency.

Drawings

FIG. 1 is a schematic view of the top view of the internal structure of the embodiment of the system for preparing the vehicle-mounted positive pressure nucleic acid detecting reagent of the present invention.

Fig. 2 is a schematic side view of the internal structure of the embodiment of the present invention.

Fig. 3 is a schematic rear view of an internal structure of the embodiment of the present invention.

Description of the figure numbering: 1-buffer module, 11-first positive pressure equipment, 12-vehicle-mounted power supply device, 13-first airtight door, 14-second airtight door, 2-reagent preparation module, 21-second positive pressure equipment, 22-reagent storage equipment, 221-freezing refrigerator, 222-refrigerating refrigerator, 23-operation table, 24-power distribution equipment, 25-airtight transfer window, 26-hand washing pool, 27-waste liquid cylinder, 28-waste garbage can, 3-ultraviolet disinfection lamp, 4-ventilation device, 5-photovoltaic power supply and 6-air conditioning device.

Detailed Description

For a clearer understanding of the present invention, reference will be made to the following detailed description of the embodiments with reference to the accompanying drawings.

Fig. 1 to fig. 3 are schematic diagrams illustrating the internal structure of an embodiment of the present invention, in which the buffer module 1 and the reagent preparing module 2 are sequentially disposed on a chassis of a van vehicle, and the buffer module 1 and the reagent preparing module 2 are completely isolated from the vehicle cab in an airtight manner to avoid contamination, but the system may also be disposed in other suitable movable structures such as a box trailer or a container. The buffer module 1 comprises a first positive pressure device 11, an on-board power supply 12 (such as a large-capacity lithium battery and/or a dedicated generator), and a first airtight door 13 connected with the reagent preparation module 2 and a second airtight door 14 connected with the external environment; the reagent preparation module 2 comprises a second positive pressure device 21, a reagent storage device 22 consisting of a freezing refrigerator 221 and a refrigerating refrigerator 222, an operation table 23 for placing reagent preparation instruments (such as a pipette, a mini centrifuge and a small vortex oscillation instrument), a hand washing pool 26, a waste liquid cylinder 27, a waste garbage can 28 and a power distribution device 24 electrically connected with the vehicle-mounted power supply device 12 and/or a commercial power and the roof photovoltaic power supply 5 for supplying power, wherein the side wall of the reagent preparation module 2 is at least provided with an airtight transmission window 25 connected with the external environment. The power distribution equipment 24 automatically distributes power supply for use through state monitoring of the vehicle-mounted power supply device 12 and connection conditions of commercial power, roof photovoltaic power supply 5 power supply and/or vehicle engine power supply, so that stable system power supply is ensured, and especially, continuous long-time stable power supply of the reagent storage equipment 22 can be ensured, so that the reagent storage equipment 22 can continuously work for a long time without limitation. In order to guarantee that the reagent preparing process is not polluted by the external environment, the buffer module 1 and the reagent preparing module 2 are respectively manufactured by the first positive pressure equipment 11 and the second positive pressure equipment 21 to form a positive pressure environment, the stable environment pressure value provided by the first positive pressure equipment 11 is higher than the stable environment pressure value provided by the second positive pressure equipment 21, and the first airtight door 13 and the second airtight door 14 of the revolving door structure can be closed automatically through the pressure difference of the two modules and the pressure difference between the buffer module 1 and the external environment. Meanwhile, in order to improve the protection effect of the system, the ultraviolet disinfection lamp 3 can be preferably arranged in the buffer module 1, the reagent preparation module 2 and the airtight transfer window 25, so that the vehicle-mounted system can be disinfected and cleaned; the buffer module 1 and the reagent preparation module 2 are also provided with independent air exchange devices 4, preferably air exchange devices with filtering functions, so that the air in the modules is kept clean; the system is also provided with an independent air conditioning device 6 different from the vehicle-mounted platform, so that pollution caused by mixed air conditioning is avoided.

Use during the system, the staff enters buffer module 1 behind second airtight door 14, after disinfecting and wearing various safeguard procedures, gets into reagent through first airtight door 13 and prepares module 2, carries out preparation and the save of nucleic acid detect reagent. When reagent needs to be transferred to a nucleic acid amplification laboratory or a sample processing laboratory, the airtight transfer window 25 arranged on the side wall of the reagent preparation module 2 is used, the module side window is opened to place the reagent into the airtight transfer window, the module side window is closed, and after the reagent is sterilized and disinfected by the ultraviolet disinfection lamp 3 in the airtight transfer window 25, an outside worker opens the outside window and takes out the detection reagent.

The buffer module 1 can provide necessary functions of changing clothes and sterilizing for people, and can also be preferably provided with a function of detecting rest of people, such as a toilet, a bathroom and the like, by utilizing a vacant position. The outside of the system can be provided with a retractable sunshade which provides more extended functions in the external environment.

On-vehicle malleation nucleic acid detect reagent preparation system both can the exclusive use, also can regard as a part to use with other portable laboratory structure combinations, form the nucleic acid detection laboratory of a complete flow.

The above description is only for the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are also within the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims

1. A vehicle-mounted positive pressure nucleic acid detection reagent preparation system is characterized by comprising a buffer module and a reagent preparation module which are mutually isolated by a first airtight door;

2. The vehicle-mounted positive pressure nucleic acid detecting reagent preparing system according to claim 1, wherein the first airtight door and the second airtight door are rotary doors that open to a side of the buffer module.

3. The vehicle-mounted positive pressure nucleic acid detection reagent dispensing system of claim 2, wherein the first positive pressure device provides a higher stable ambient pressure value than the second positive pressure device.

4. The vehicle-mounted positive pressure nucleic acid detection reagent preparation system of claim 1, wherein the reagent storage device comprises a freezing refrigerator at-20 ℃ and a refrigerating refrigerator at 4 ℃.

5. The vehicle-mounted positive pressure nucleic acid detection reagent preparation system of claim 1, wherein the reagent preparation module further comprises a hand sink, a waste liquid tank, and a waste garbage can.

6. The vehicle-mounted positive pressure nucleic acid detection reagent preparing system according to claim 1, wherein the buffer module and the reagent preparing module are further provided with an ultraviolet disinfection lamp and a ventilation device.

7. The vehicle-mounted positive pressure nucleic acid detecting reagent preparing system according to claim 1, wherein an ultraviolet disinfection lamp is further disposed in the airtight transfer window.

8. The vehicle-mounted positive pressure nucleic acid detection reagent preparation system of claim 1, wherein the external power supply comprises a mains power interface and/or a photovoltaic power supply disposed on the top outside the system.

9. The vehicle-mounted positive pressure nucleic acid detecting reagent preparing system according to claim 1, further comprising an independent air conditioner.