CN212861211U - Vehicle-mounted nucleic acid detection amplification and product analysis system - Google Patents
Vehicle-mounted nucleic acid detection amplification and product analysis system Download PDFInfo
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- CN212861211U CN212861211U CN202021335967.2U CN202021335967U CN212861211U CN 212861211 U CN212861211 U CN 212861211U CN 202021335967 U CN202021335967 U CN 202021335967U CN 212861211 U CN212861211 U CN 212861211U
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Abstract
The utility model relates to an on-vehicle nucleic acid detects amplification and result analytic system, guarantee one-way personnel simultaneously through the whole negative pressure laboratory that will be used for nucleic acid to detect amplification and result analysis and establish on vehicle platform, the airtight access way of article, can be at any time as required fast migration, arrange in a flexible way to the area of needs most, can effectively improve hot area nucleic acid detection amplification and result analytical ability through reasonable allotment, promote nucleic acid detection efficiency, need not the negative pressure laboratory of repeated construction simultaneously, avoid the wasting of resources.
Description
Technical Field
The utility model relates to a pathogen detection equipment technical field especially relates to an on-vehicle nucleic acid detects amplification and product analysis system.
Background
The novel coronavirus pathogen is an airborne virus pathogen with the characteristics of strong infectivity and strong pathogenicity, and often presents explosive diffusion infection in community people, thereby forming a very serious threat to the life health of people.
Because there is no specific medicine for pneumonia and other diseases caused by novel coronavirus pathogen at present, the early discovery and isolation of infected people become the most effective means for preventing and treating novel coronavirus pathogen, and the nucleic acid detection method which is most commonly used at present is a screening means which is acknowledged to be high in accuracy and reliable in result.
For a sudden epidemic situation, a large number of patients need to perform nucleic acid detection in a short time, and at the moment, the number of negative pressure laboratories in a hot spot area is insufficient, and the capabilities of nucleic acid detection amplification and product analysis cannot meet the requirements, so that the nucleic acid detection efficiency is reduced.
SUMMERY OF THE UTILITY MODEL
For solving prior art's is not enough, the utility model provides an on-vehicle nucleic acid detects amplification and result analytic system, guarantee one-way personnel simultaneously on vehicle platform through the whole negative pressure laboratory that will be used for nucleic acid to detect amplification and result analysis, the airtight access way of article, nucleic acid detection amplification and result analytic ability that can the quick travel deployment are provided, can effectively improve hot spot area nucleic acid detection amplification and result analytic ability through reasonable allotment, promote nucleic acid detection efficiency, need not the rebuilt negative pressure laboratory simultaneously, avoid the wasting of resources.
In order to achieve the above object, the utility model discloses the technical scheme who adopts includes:
a vehicle-mounted nucleic acid detection, amplification and product analysis system is characterized by comprising an inlet buffer module, a nucleic acid amplification and data analysis module, a dirt disposal module and an outlet buffer module, wherein the inlet buffer module, the nucleic acid amplification and data analysis module, the dirt disposal module and the outlet buffer module are mutually isolated;
the inlet buffer module comprises a first negative pressure device, a first airtight door connected with the nucleic acid amplification and data analysis module and a second airtight door connected with the external environment;
the nucleic acid amplification and data analysis module comprises second negative pressure equipment and a PCR analyzer, and the side wall of the nucleic acid amplification and data analysis module is at least provided with an airtight transmission window connected with the external environment;
the pollutant disposal module comprises a third negative pressure device, a third airtight door connected with the nucleic acid amplification and data analysis module and a fourth airtight door connected with the outlet buffer module; the dirt disposal module further comprises at least one airtight transfer window connected to an external environment;
the outlet buffer module comprises fourth negative pressure equipment and a fifth airtight door connected with the external environment, and is further provided with a power generation device.
Further, the stable ambient pressure value provided by the second negative pressure device is lower than the stable ambient pressure value provided by the third negative pressure device, and the stable ambient pressure value provided by the third negative pressure device is lower than the stable ambient pressure values provided by the first negative pressure device and the second negative pressure device.
Further, the nucleic acid amplification and data analysis module is also provided with a shock absorption connecting structure; the shock absorbing attachment structure includes at least one horizontal shock absorbing spring.
Further, the fifth airtight door is an airtight door with a large opening, and the large opening accommodates the power generation device to enter and exit; the outlet buffer module is also provided with a lifting platform for retracting the power generation device.
Further, the sewage disposal module is also provided with a hand washing basin, a waste liquid cylinder and a waste garbage bin.
Further, the inlet buffer module, the nucleic acid amplification and data analysis module, the dirt disposal module and the outlet buffer module are also provided with an ultraviolet disinfection lamp and a ventilation device.
Further, an ultraviolet disinfection lamp is arranged in the airtight transfer window.
Further, the inlet buffer module, the nucleic acid amplification and data analysis module, the sewage disposal module and the outlet buffer module are powered by external power and/or the power generation device; the external power supply comprises a mains supply interface and/or a photovoltaic power supply arranged on the top of the outer side of the system.
Further, the system also comprises an independent air conditioning device.
The utility model has the advantages that:
adopt on-vehicle nucleic acid detection amplification and product analysis system have realized establishing the complete negative pressure laboratory that has the entry on vehicle platform, export buffer module, can accomplish nucleic acid detection amplification and product analysis's whole flows in this system, make nucleic acid detection amplification and product analysis ability break away from the constraint of fixed laboratory, can be at any time according to needs quick travel, arrange to the area of needs most in a flexible way, make full use of current nucleic acid detection amplification and product analysis ability, reduce interim negative pressure laboratory construction pressure, be the ideal solution to the large amount of detection demands of emergency.
Drawings
FIG. 1 is a schematic diagram of the internal structure of an embodiment of the system for detecting, amplifying and analyzing nucleic acid on board a vehicle according to the present invention.
Fig. 2 is a schematic view of the internal bottom structure of the embodiment of the present invention.
Description of the figure numbering: 1-inlet buffer module, 11-first negative pressure equipment, 12-first airtight door, 13-second airtight door, 2-nucleic acid amplification and data analysis module, 21-second negative pressure equipment, 22-PCR analyzer, 24-airtight transmission window, 3-dirt disposal module, 31-third negative pressure equipment, 32-third airtight door, 33-fourth airtight door, 4-outlet buffer module, 41-fourth negative pressure equipment, 42-fifth airtight door and 43-power generation device.
Detailed Description
For a clearer understanding of the present invention, reference will be made to the following detailed description of the embodiments with reference to the accompanying drawings.
Fig. 1 and fig. 2 show schematic diagrams of internal structures of an embodiment of the present invention, in this embodiment, the inlet buffer module 1, the nucleic acid amplification and data analysis module 2, the contaminant treatment module 3, and the outlet buffer module 4 are sequentially disposed on a chassis of a van vehicle, and the inlet buffer module 1, the nucleic acid amplification and data analysis module 2, the contaminant treatment module 3, and the outlet buffer module 4 are completely isolated from a cab in an airtight manner to avoid contamination, and of course, the system may also be disposed in other suitable movable structures such as a trailer or a container. The inlet buffer module 1 comprises a negative pressure device 11, a first airtight door 12 connected with the nucleic acid amplification and data analysis module 2 and a second airtight door 13 connected with the external environment; when a worker needs to enter the nucleic acid amplification and data analysis module 2 for operation, the worker must first pass through the entrance buffer module 1. The nucleic acid amplification and data analysis module 2 comprises a second negative pressure device 21, a PCR analyzer 22, a computer for analyzing data and a buffer room storage cabinet for temporarily storing articles, wherein the side wall of the nucleic acid amplification and data analysis module 2 is at least provided with an airtight transmission window 24 connected with the external environment, and an article transmission safety channel with the outside is formed through the airtight transmission window 24; the nucleic acid amplification and data analysis module 2 is preferably further configured with a power distribution device for electrically connecting to mains electricity, a generator power supply and/or a roof photovoltaic power supply. The power distribution equipment preferably automatically distributes power supply to use through the connection condition of the mains supply, the power supply of the generator, the power supply of the roof photovoltaic power supply and/or the power supply of the vehicle engine, and the stability of the system power supply is ensured. In order to reduce the possible impact of shock on the experimental operation, the experimental equipment (e.g., the PCR analyzer 22) in the nucleic acid amplification and data analysis module 2 is preferably placed on a stage provided with a shock absorbing attachment structure that preferably absorbs shock with at least one horizontal shock absorbing spring. The waste disposal module 3 is provided with at least one airtight transfer window 24 connected to the external environment for safe transfer of waste and the like. In order to ensure that the experiment process is not polluted by the external environment, the inlet buffer module 1, the nucleic acid amplification and data analysis module 2, the pollutant disposal module 3 and the outlet buffer module 4 are respectively provided with independent negative pressure equipment to produce a negative pressure environment, preferably, the negative pressure equipment of each module shown in FIG. 2 is respectively arranged at the bottom of the module, and the space in the module is not occupied; the stable ambient pressure value provided by the second negative pressure device 21 is lower than the stable ambient pressure value provided by the third negative pressure device 31, and the stable ambient pressure value provided by the third negative pressure device 31 is lower than the stable ambient pressure values provided by the first negative pressure device 11 and the second negative pressure device 21, so that at least three-order negative pressure gradient environment is formed, and dangerous substances are completely prevented from leaking to the external environment; for example, one preferred pressure gradient is set as: the second negative pressure device 21 provides a steady ambient pressure value of-25 Pa, the third negative pressure device 31 provides a steady ambient pressure value of-15 Pa, and the first negative pressure device 11 and the second negative pressure device 21 provide a steady ambient pressure value of-10 Pa. Meanwhile, the air-tight door connected with each module can be preferably set to be a revolving door structure which is opened by rotating towards the higher side of the ambient pressure value, and the pressure difference between the two modules can enable a worker to feel proper damping when opening the air-tight door and enable the air-tight door of the revolving door structure to be closed automatically, so that the air-tight damage caused by forgetting to close the door is avoided. In order to improve the protection effect of the system, ultraviolet disinfection lamps can be preferably arranged in the inlet buffer module 1, the nucleic acid amplification and data analysis module 2, the pollutant disposal module 3, the outlet buffer module 4 and the airtight transfer window 24, so that the vehicle-mounted system can be disinfected and cleaned; the inlet buffer module 1, the nucleic acid amplification and data analysis module 2, the dirt disposal module 3 and the outlet buffer module 4 are also provided with independent air exchange devices, preferably air exchange devices with filtering functions, so that the air in the modules is kept clean; the system is also provided with an independent air conditioning device different from the vehicle-mounted platform, so that pollution caused by a mixed air conditioner is avoided.
The outlet buffer module 4 is further provided with a power generation device 43 (such as a special generator equipped with a large-capacity lithium battery) and a preferred lifting platform for the power generation device to move in and out; meanwhile, in order to facilitate the movement of the power generation device 43, the fifth airtight door 42 is preferably a large-opening airtight door, such as a split airtight door provided at the rear of the system structure. The lifting platform is mainly used for facilitating the movement of the generating device 43 with large self weight into and out of the outlet buffer module 4, and particularly for meeting the vertical movement requirement when the generating device 43 enters and exits the outlet buffer module 4. In the using process, the fifth airtight door 42 is opened, the lifting platform loaded with the power generation device 43 firstly translates to the outside of the outlet buffer module 4, and then the whole body vertically descends to be flush with the ground of the external environment, so that the power generation device 43 can be smoothly moved to the external environment, the situation that the power generation device 43 is carried by manpower is avoided, and the power generation device 43 can be vertically lifted by the lifting platform and then translated into the outlet buffer module 4 when needing to be retracted; of course, the translation and vertical movement operations of the lifting platform may be two steps performed in sequence, or may be performed together in a single movement process. The specific structure of the lifting platform can refer to a vehicle-mounted wheelchair barrier-free lifting device and the like widely used in the prior art.
Use during the system, at first remove power generation facility 43 to export buffer module 4 through lift platform outside, and preferred power generation facility 43 can remote control operation and freely remove in the certain limit, conveniently arranges the power supply line. The staff enters the entrance buffer module 1 after passing through the second airtight door 13, and enters the nucleic acid amplification and data analysis module 2 through the first airtight door 12 after disinfecting and wearing various protective measures to perform analysis operation; after the work is finished, the waste is required to enter the waste treatment module 3 through the third airtight door 32 to be properly treated, then enters the outlet buffer room through the fourth airtight door 33, finally leaves the system through the fifth airtight door 42, the whole movement line of personnel is in one-way movement, and the safety is guaranteed to the maximum extent. The required nucleic acid detection sample is transmitted by using an airtight transmission window 24 arranged on the side wall of the nucleic acid amplification and data analysis module 2, a module side window is opened to place the sample in, the module side window is closed, and after the sample is sterilized and disinfected by an ultraviolet disinfection lamp in the airtight transmission window 24, an inner side worker opens an inner side window to take out the sample.
For the entrance buffer module 1, besides providing necessary functions of changing clothes and sterilizing for personnel, a rest function of detecting personnel, such as a washroom, a bathroom and the like, can be preferably arranged by utilizing a vacant position.
On-vehicle nucleic acid detect amplification and result analytic system both can the exclusive use, also can regard as a part to use with other portable laboratory structure combinations, form the nucleic acid detection laboratory of a complete flow.
The above description is only for the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are also within the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (9)
1. A vehicle-mounted nucleic acid detection, amplification and product analysis system is characterized by comprising an inlet buffer module, a nucleic acid amplification and data analysis module, a dirt disposal module and an outlet buffer module, wherein the inlet buffer module, the nucleic acid amplification and data analysis module, the dirt disposal module and the outlet buffer module are mutually isolated;
the inlet buffer module comprises a first negative pressure device, a first airtight door connected with the nucleic acid amplification and data analysis module and a second airtight door connected with the external environment;
the nucleic acid amplification and data analysis module comprises second negative pressure equipment and a PCR analyzer, and the side wall of the nucleic acid amplification and data analysis module is at least provided with an airtight transmission window connected with the external environment;
the pollutant disposal module comprises a third negative pressure device, a third airtight door connected with the nucleic acid amplification and data analysis module and a fourth airtight door connected with the outlet buffer module; the dirt disposal module further comprises at least one airtight transfer window connected to an external environment;
the outlet buffer module comprises fourth negative pressure equipment and a fifth airtight door connected with the external environment, and is further provided with a power generation device.
2. The system of claim 1, wherein the second negative pressure device provides a stable ambient pressure value that is lower than the stable ambient pressure value provided by the third negative pressure device, and the third negative pressure device provides a stable ambient pressure value that is lower than the stable ambient pressure values provided by the first negative pressure device and the second negative pressure device.
3. The system of claim 2, wherein the nucleic acid amplification and data analysis module is further provided with a shock absorbing linkage; the shock absorbing attachment structure includes at least one horizontal shock absorbing spring.
4. The system of claim 2, wherein the fifth airtight door is a large opening airtight door, the large opening accommodating ingress and egress of the power generation device; the outlet buffer module is also provided with a lifting platform for retracting the power generation device.
5. A system as claimed in claim 2, wherein the waste disposal module is further provided with a hand wash basin, a waste tank and a waste bin.
6. The system of any one of claims 1 to 5, wherein the inlet buffer module, the nucleic acid amplification and data analysis module, the waste disposal module and the outlet buffer module are further provided with an ultraviolet disinfection lamp and a ventilation device.
7. The system of any one of claims 1 to 5, wherein an ultraviolet disinfection lamp is further disposed within the hermetic transfer window.
8. The system of any one of claims 1 to 5, wherein the inlet buffer module, nucleic acid amplification and data analysis module, contaminant disposal module and outlet buffer module are powered by an external power supply and/or the power generation device; the external power supply comprises a mains supply interface and/or a photovoltaic power supply arranged on the top of the outer side of the system.
9. The system of any one of claims 1 to 5, further comprising a separate air conditioning unit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021335967.2U CN212861211U (en) | 2020-07-09 | 2020-07-09 | Vehicle-mounted nucleic acid detection amplification and product analysis system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021335967.2U CN212861211U (en) | 2020-07-09 | 2020-07-09 | Vehicle-mounted nucleic acid detection amplification and product analysis system |
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| Publication Number | Publication Date |
|---|---|
| CN212861211U true CN212861211U (en) | 2021-04-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021335967.2U Active CN212861211U (en) | 2020-07-09 | 2020-07-09 | Vehicle-mounted nucleic acid detection amplification and product analysis system |
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|---|---|
| CN (1) | CN212861211U (en) |
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- 2020-07-09 CN CN202021335967.2U patent/CN212861211U/en active Active
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