CN207717626U - A kind of fluorescence immune chromatography analyzer - Google Patents
A kind of fluorescence immune chromatography analyzer Download PDFInfo
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- CN207717626U CN207717626U CN201721208153.0U CN201721208153U CN207717626U CN 207717626 U CN207717626 U CN 207717626U CN 201721208153 U CN201721208153 U CN 201721208153U CN 207717626 U CN207717626 U CN 207717626U
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- photoelectric sensor
- monochromatic
- test strips
- immune chromatography
- fluorescence immune
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Abstract
The utility model belongs to medicine apparatus field, it is related to testing and analyzing, especially a kind of fluorescence immune chromatography analyzer, including a detection card, a test strips are embedded in the upper surface of the detection card, there are one photoelectric sensors for corresponding position installation above the test strips, the induction end of the photoelectric sensor is oppositely arranged with test strips homonymy, it is separately installed with a monochromatic source in the both sides of the photoelectric sensor, the glossing up of two monochromatic source is set as rectangle, and the monochromatic source uses wavelength for the monochromatic LED of 365nm;The signal output end of the photoelectric sensor is connected with central processing module and data storage module.
Description
Technical field
The utility model belongs to medicine apparatus field, is related to testing and analyzing, especially a kind of fluorescence immune chromatography analyzer.
Background technology
Fluorescence immune chromatography technology is one kind that immunofluorescence technique and Traditional immunochromatographic technology are combined development innovation
Quantitative novel detection technique.The technology retain colloidal gold immunochromatographimethod technical operation is easy, detection quickly, strong excellent of portability
Point is outer, and also enhancing technology by fluorescent tracing realizes the accurate quantification of testing result.This technology and traditional Fast Detection Technique
Performance compares, and has the advantages that sensitivity higher, detection range are wider and cheap.Detection sensitivity is high compared with its colloidal gold method
2~3 orders of magnitude.The advantage of fluorescence immune chromatography technology uniqueness be quick on the draw, specifically, quickly, easy, accuracy rate is high, especially
It, which can meet, quickly goes out inspection result within 10 minutes, fluorescence immune chromatography method is as a kind of method for quickly detecting in medicine
Inspection field is widely used.
Fluorescence immune chromatography analyzer is sample yin and yang attribute or test samples testing concentration in automatic interpretation check card
Instrument.Its structure include one in the installation of the top of check card there are one CCD, it is monochromatic that the both sides of the CCD are symmetrically installed that there are one LED
Light source, above-mentioned two LED monochromatic sources, the test strips corresponding position for being radiated in check card.
T lines (detection line) and C lines (nature controlling line) in above-mentioned test strips are acquired by CCD, later according to acquisition
The gray value of image judges the yin and yang attribute and concentration of specimens of sample to be tested.
In practical operation, gold mark analyzer exists certain insufficient in use at present, has the disadvantage that:
1. existing light source mostly uses ordinary light source, and the outgoing optical cross-section of ordinary light source is circle, should in verification process
The light that light source is sent out can be not only irradiated on the T lines (detection line) or C lines (nature controlling line) of test strips in check card, can be also irradiated to
On the shell of check card, the SKIN RETURN light of check card is bigger on the gray value influence of CCD generation images, this makes CCD produce
The gray value of raw image is locally unstable, be easy to cause sample feminine gender and it is positive judge it is inaccurate, especially in weakly positive or weak
Negative sample more easily determines mistake.
The detection poor repeatability of 2.CCD Image Acquisition principle fluorescence immune chromatography analyzers, the position of check card is slightly not
It is same also to influence whether testing result.Therefore some can only be done qualitatively or half with the gold mark analyzer of ccd image acquisition principle
Quantitative detection, cannot do quantitative detection, that is, be only able to detect either with or without a certain substance, but cannot be accurately detected this
The content of kind substance is how many.
3. current fluorescence immune chromatography analyzer by CCD due to being limited, its service life is shorter, and CCD is generated heat
Its service life that limits of problem is only 10,000 hours, therefore the service life of gold mark analyzer is no more than 2 years at present.
Utility model content
The purpose of the utility model is to overcome the deficiencies in the prior art, provide a kind of precision height, repeatability is good, uses
A kind of fluorescence immune chromatography analyzer of long lifespan.
The purpose of this utility model takes following technical scheme to realize:
A kind of fluorescence immune chromatography analyzer, including a detection block, embedded with an examination in the upper surface of the detection card
Paper slip, it is characterised in that:Corresponding position above the test strips is installed there are one photoelectric sensor, the photoelectric sensor
Induction end is oppositely arranged with test strips homonymy, is separately installed with a monochromatic source in the both sides of the photoelectric sensor, this two
The light hole of monochromatic source is set as rectangle, and the monochromatic source uses wavelength for the monochromatic LED of 365nm.
Moreover, the signal output end of the photoelectric sensor is connected with central processing module and data storage module.
The advantages of the utility model and good effect are:
1, this analyzer replaces CCD using photoelectric sensor, the advantage is that, photoelectric sensor technology is ripe, normally makes
Can substantially it be prolonged the service life on the basis of analyser function retains at 10 years or more, therefore with the service life.Using monochromatic light
Source substitutes ordinary light source, and the glossing up of monochromatic source is set as rectangle, then adjustable light source exposes to the suitable position of test strips
It sets, prevents light source from exposing to the shell of check card, effectively avoid interference caused by illumination, improve the precision of detection;This analyzer
Using the monochromatic light of 365nm as monochromatic source, and the monochromatic light of 365nm can make test strips inspire the light that wavelength is 615nm,
And the light of the wavelength finally arrives at photoelectric sensor.
2, the signal output end of photoelectric sensor is connected with central processing module and data memory device in this analyzer, then
Signal convenient for acquiring line array CCD is stored and is analyzed.
3, this analyzer uses light hole that can effectively reduce external light source as light source for the monochromatic light of the 365nm of rectangle and shines
Reflective caused interference is penetrated, the precision and repeatability of detection are promoted, it at the same time, can by the mature technology of photoelectric sensor
The service life of effective lifting device, and there is data storage, the function of analysis can be used as reference instrument configuration hospital, inspection
Survey mechanism and inspection and quarantine station etc.;Standard method for quickly detecting can be used as in medical inspection, scientific research and inspection and quarantine row
Industry is promoted the use of, and detection data directly can be quickly provided.
Description of the drawings
Fig. 1 is the structural schematic diagram of the utility model;
Fig. 2 is the structural schematic diagram in monochromatic source portion in Fig. 1;
Fig. 3 is the module diagram of the utility model.
Specific implementation mode
The embodiments of the present invention are further described below in conjunction with attached drawing;The present embodiment is descriptive, is not
Limited, it cannot thus limit the scope of protection of the utility model.
A kind of fluorescence immune chromatography analyzer, including a detection block, embedded with an examination in the upper surface of the detection card 3
The innovation of paper slip 4, the utility model is that there are one photoelectric sensors 1 for the corresponding position installation above the test strips, should
The induction end of photoelectric sensor is oppositely arranged with test strips homonymy, and a list is separately installed in the both sides of the photoelectric sensor
The glossing up 5 of color light source 2, two monochromatic source is set as rectangle, and the monochromatic source uses wavelength for the monochromatic LED of 365nm.
In the present embodiment, the signal output end of the photoelectric sensor is connected with central processing module and data storage mould
Block.
In the present embodiment, installation temperature capacity checking device can be also assisted, according to the temperature braking correction check number for examining scene
According to.
The operation principle of the utility model is:
When the utility model at work, monochromatic source is adjusted irradiating angle by operating personnel, its emergent light is made to project completely
Suitable position and angle in test strips upper surface, the light projection that photoelectric sensor can reflect test strips at this time to photoelectric sensing
The induction end of device, and the signal output end of photoelectric sensor can then export the signal of induction end to central processing module and data
In storage module.
Exterior PC, microcontroller or other devices can be used in above-mentioned central processing module, and data storage module can be independent
In central processing module, can also be mounted in central processing module, such as the storage element in PC.Above-mentioned central processing module may be used also
Connect printer or other auxiliary devices.
This analyzer uses glossing up that can effectively reduce external light source irradiation as light source for the monochromatic light of the 365n of rectangle
Interference caused by reflective, promotes the precision and repeatability of detection, at the same time, can have by the mature technology of photoelectric sensor
The service life of lifting device is imitated, and there is data storage, the function of analysis can be used as reference instrument configuration hospital, detection
Mechanism and inspection and quarantine station etc.;Standard method for quickly detecting can be used as in medical inspection, scientific research and inspection and quarantine industry
It promotes the use of, detection data directly can be quickly provided.
Claims (2)
1. a kind of fluorescence immune chromatography analyzer, including a detection block, a test paper is embedded in the upper surface of the detection card
Item, it is characterised in that:There are one photoelectric sensor, the senses of the photoelectric sensor for corresponding position installation above the test strips
It should hold and be oppositely arranged with test strips homonymy, a monochromatic source is separately installed in the both sides of the photoelectric sensor, two list
The light hole of color light source is set as rectangle, and the monochromatic source uses wavelength for the monochromatic LED of 365nm.
2. a kind of fluorescence immune chromatography analyzer according to claim 1, it is characterised in that:The letter of the photoelectric sensor
Number output end is connected with central processing module and data storage module.
Priority Applications (1)
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CN201721208153.0U CN207717626U (en) | 2017-09-20 | 2017-09-20 | A kind of fluorescence immune chromatography analyzer |
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CN201721208153.0U CN207717626U (en) | 2017-09-20 | 2017-09-20 | A kind of fluorescence immune chromatography analyzer |
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CN207717626U true CN207717626U (en) | 2018-08-10 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109298179A (en) * | 2018-11-29 | 2019-02-01 | 福州大学 | A kind of immunochromatography detection system and its Background Recognition method |
CN117054410A (en) * | 2023-10-12 | 2023-11-14 | 乐福思健康产业股份公司 | Detection method of colloidal gold immunochromatography analyzer |
-
2017
- 2017-09-20 CN CN201721208153.0U patent/CN207717626U/en active Active
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109298179A (en) * | 2018-11-29 | 2019-02-01 | 福州大学 | A kind of immunochromatography detection system and its Background Recognition method |
CN109298179B (en) * | 2018-11-29 | 2023-09-01 | 福州大学 | Immunochromatography detection system and background recognition method thereof |
CN117054410A (en) * | 2023-10-12 | 2023-11-14 | 乐福思健康产业股份公司 | Detection method of colloidal gold immunochromatography analyzer |
CN117054410B (en) * | 2023-10-12 | 2024-02-06 | 乐福思健康产业股份公司 | Detection method of colloidal gold immunochromatography analyzer |
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Legal Events
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TR01 | Transfer of patent right |
Effective date of registration: 20210331 Address after: Room 503, gate 3, block F, Haitai green industrial base, No.6 Haitai development road, Huayuan Industrial Zone, Binhai New Area, Tianjin Patentee after: Puhaoda Biotechnology (Tianjin) Co.,Ltd. Address before: No.52 Jintang road Hedong District Tianjin 300170 Patentee before: TIANJIN RUIZE ANALYTICAL INSTRUMENT Co.,Ltd. |
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TR01 | Transfer of patent right |