CN204177810U - Plasma proteins quick analysis system - Google Patents
Plasma proteins quick analysis system Download PDFInfo
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- CN204177810U CN204177810U CN201420668573.7U CN201420668573U CN204177810U CN 204177810 U CN204177810 U CN 204177810U CN 201420668573 U CN201420668573 U CN 201420668573U CN 204177810 U CN204177810 U CN 204177810U
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Abstract
The utility model discloses a kind of plasma proteins quick analysis system.It relates to biochemical analyzer field, and specifically a kind of latex strengthens scattering turbidimetry measurement apparatus, is applicable to medical institutions' plasma proteins clinical rapid checking such as hospital, community medicine center.System composition of the present utility model comprises several part such as casing and the detection of built-in Single Chip Microcomputer (SCM) system, geometrical light-path module, laser emitting module, Quick Response Code read module, thermal printer, touch-screen and photosignal, data acquisition conversion, temperature control circuit, clock circuit, power-supplying circuit.The utility model utilizes laser light scattering than turbid principle, selects laser parallel light pipe to make light source, adopts latex to strengthen and detects, increase substantially reaction sensitivity; Directly can read matched reagent box Quick Response Code and obtain typical curve, be not used as typical curve, be not used as blank, detect accurately and reliably; Adopt very color touch-screen inputoutput data, man-machine interface is friendly; Directly printed by built-in printer, result immediate delivery.
Description
Technical field
The utility model relates to biochemical analyzer field, and specifically a kind of latex strengthens scattering turbidimetry measurement apparatus, is applicable to medical institutions' plasma proteins clinical rapid checking such as hospital, community medicine center.
Background technology
Blood plasma specific protein detection technique originates from De Ling company of the U.S., and De Ling company of the U.S. (DADE BEHRING INC) to be merged in October, 1997 by two companies in the richest experience in ecsomatics field-DADE company of the U.S. and German BEHRING company to form.BEHRING company is founded in 1904 by the first medical science Nobel laureate Emil Von doctor Behring, leads over the world with the research of blood plasma specific protein and clinical diagnosis.
The detection of plasma proteins has very important clinical meaning, and in the diagnosis of some chronic disease, the detection of plasma proteins is the diagnosis index of very early time, as chronic kidney disease, and diabetes, rheumatism etc.
Traditional detection method difinite quality and qualitative sxemiquantitative two kinds.Wherein have latex agglutination qualitatively, the false-positive chance of the method is many, eliminate by a lot of hospital.Also have a kind of mode to be the index adopting biochemical instruments to detect albumen, but biochemical instruments is by the restriction of its method, the albumen that molecular weight is large can only be detected, as immunoglobulin (Ig) and albumin.And clinically required for the molecular weight exactly known be accurate to the protein content of ng/ml or pg/ml.The Detection Techniques of a kind of extensive employing that transmitted light turbidimetry has developed out since being the nearest more than ten years, are applicable to the testing requirement of plasma proteins, can be used for detecting the most protein in body fluid.But because the absorbance of sample not only depends on the concentration of compound, be also subject to the very large impact of its cross-linked areas, so due to the restriction of transmission beam method optical detector technology, light intensity can not too high can not be too low, cause insufficient sensitivity, measurement range is narrower.
So work out one more accurate plasma proteins analyser fast, clinical medicine detection is significant, concerning vast clinical and inspection man author, the quality that specific protein detects can be ensured by special blood plasma protein analyzer, while ensureing result accuracy, can also to the relation multianalysis between the clinical value of these specific proteins and disease development, thus better utilize these indexs, for medical diagnosis on disease and co-treatment provide better service.
Summary of the invention
In order to overcome the deficiency of existing specific protein detecting instrument, the utility model adopts latex to strengthen scattering immunoturbidimetry and develops a kind of plasma proteins quick analytic instrument.Latex immunoassay is a kind of micro-heterotope Examined effect, after utilizing small latex particle to connect antibody, produces the technology such as the change of turbidity or scattered light measure antigenic content with corresponding antigens after combining in the liquid phase.The utility model utilizes latex particle in conjunction with scattering method, greatly can strengthen the detection perform of plasma proteins, and for the detection of SAA, susceptibility can < Img/L.There is intelligent temperature control, easy and simple to handle, volume is little, the advantage that lightweight, detection speed is fast; Be not used as typical curve, be not used as blank, direct reading reagent box Quick Response Code just can obtain typical curve, and accurately and reliably, result is directly printed by built-in printer result, immediate delivery.
The purpose of this utility model is achieved in that
Plasma proteins quick analysis system, comprise casing, and the built-in Single Chip Microcomputer (SCM) system be arranged in casing, the power-supplying circuit be connected respectively with built-in Single Chip Microcomputer (SCM) system, Quick Response Code read module, laser emitting module, data acquisition circuit, temperature control circuit, clock circuit; Described built-in Single Chip Microcomputer (SCM) system is connected with switched communication interface, touch screen and thermal printer simultaneously;
Described laser emitting module is connected with geometrical light-path module, and geometrical light-path model calling has amplifying circuit, and amplifying circuit is connected with the data acquisition circuit be connected with built-in Single Chip Microcomputer (SCM) system;
Described geometrical light-path module is provided with cuvette;
Described built-in Single Chip Microcomputer (SCM) system is STC Single Chip Microcomputer (SCM) system, and Single Chip Microcomputer (SCM) system adopts STC12C5A60S2 as main control unit, and possess single clock, monocyclic ability, arithmetic speed is the twelvefold of common 8051 serial CPU;
Described geometrical light-path module is disposal molding processing, inside arranges reaction cup room, lasing light emitter room is being set perpendicular to reaction cup chamber axial direction and photoelectricity accepts transducer room, and be path channels between lasing light emitter room and sensor holding chamber, in path channels, optical module is set, reaction cup inductor is set in the bottom of reaction cup room simultaneously;
Described laser emitting module comprises laser tube, constant-current circuit, lens and crystal; Laser tube selects red LD laser parallel light pipe, launches the laser beam of the high depth of parallelism, measures wavelength 650nm; The electric current of the wide region that constant-current circuit provides external power converts the steady current needed for laser tube to, and lens are used for focusing on and expanding, and crystal is used for changing the color of light;
Described Quick Response Code read module directly reads specific protein matched reagent box Quick Response Code and obtains specific curves, and be not used as typical curve, be not used as blank, guarantee reagent and family curve are definitely identical, detects accurately and reliably;
Described temperature control circuit comprises temperature detection and computer heating control two parts; What temperature detection adopted is DB18B20 intelligent temperature sensor, and what device of heating adopted is PTC ceramic heating flake; By being fixed on the temperature sensors in light path module, the working temperature of real-time detecting system, ensures that the testing environment temperature of analyser the best is 37
0c.
positive beneficial effect:this instrument utilizes laser light scattering than turbid principle, selects laser parallel light pipe to make light source, adopts latex to strengthen and detects, increase substantially reaction sensitivity; Directly can read matched reagent box Quick Response Code and obtain typical curve, be not used as typical curve, be not used as blank, detect accurately and reliably; Adopt very color touch-screen inputoutput data, man-machine interface is friendly; Directly printed by built-in printer, result immediate delivery.
Accompanying drawing explanation
Fig. 1 is the block diagram of system of the present utility model.
Embodiment
Below in conjunction with accompanying drawing, the utility model is described further:
As shown in Figure 1, plasma proteins quick analysis system, comprise casing, and be arranged on the built-in Single Chip Microcomputer (SCM) system in casing, the power-supplying circuit be connected respectively with built-in Single Chip Microcomputer (SCM) system, Quick Response Code read module, laser emitting module, data acquisition circuit, temperature control circuit, clock circuit; Described built-in Single Chip Microcomputer (SCM) system is connected with switched communication interface, touch screen and thermal printer simultaneously;
Described laser emitting module is connected with geometrical light-path module, and geometrical light-path model calling has amplifying circuit, and amplifying circuit is connected with the data acquisition circuit be connected with built-in Single Chip Microcomputer (SCM) system;
Described geometrical light-path module is provided with cuvette;
Described built-in Single Chip Microcomputer (SCM) system is STC Single Chip Microcomputer (SCM) system, and Single Chip Microcomputer (SCM) system adopts STC12C5A60S2 as main control unit, and possess single clock, monocyclic ability, arithmetic speed is the twelvefold of common 8051 serial CPU;
Described geometrical light-path module is disposal molding processing, inside arranges reaction cup room, lasing light emitter room is being set perpendicular to reaction cup chamber axial direction and photoelectricity accepts transducer room, and be path channels between lasing light emitter room and sensor holding chamber, in path channels, optical module is set, reaction cup inductor is set in the bottom of reaction cup room simultaneously;
Described laser emitting module comprises laser tube, constant-current circuit, lens and crystal; Laser tube selects red LD laser parallel light pipe, launches the laser beam of the high depth of parallelism, measures wavelength 650nm; The electric current of the wide region that constant-current circuit provides external power converts the steady current needed for laser tube to, and lens are used for focusing on and expanding, and crystal is used for changing the color of light;
Described Quick Response Code read module directly reads specific protein matched reagent box Quick Response Code and obtains specific curves, and be not used as typical curve, be not used as blank, guarantee reagent and family curve are definitely identical, detects accurately and reliably;
Described temperature control circuit comprises temperature detection and computer heating control two parts; What temperature detection adopted is DB18B20 intelligent temperature sensor, and what device of heating adopted is PTC ceramic heating flake; By being fixed on the temperature sensors in light path module, the working temperature of real-time detecting system, ensures that the testing environment temperature of analyser the best is 37
0c.
The detection laser that laser emitting module sends is by being placed on the cuvette in geometrical light-path, produce scattering effect, its scattered light is through the shaping of geometrical light-path module and conditioning, receive through photoelectric sensor device, detection amplifying circuit becomes the voltage signal that can be received by data acquisition circuit, become digital signal through data acquisition circuit, enter Single Chip Microcomputer (SCM) system; Quick Response Code read module reads the typical curve of particular agent, after interpolation, filtering, conversion, calculating being carried out to the data received by Single Chip Microcomputer (SCM) system, become the index that can reflect liquid protein content in cuvette, shown by touch-screen, also by thermal-sensitive printer printing out, for staff; Touch-screen provides the input control of system works simultaneously, can be realized the operation needed by man-machine conversation; Temperature control circuit ensures that the temperature of system works is in the scope of license; Clock circuit provides stable clock signal; The data communication function that interactive communication interface provides unit external, is convenient to networking work and system debug; Power supply unit provides the direct supply needed for the work of system modules.
STC Single Chip Microcomputer (SCM) system is the carrier of system software work, the various computings of completion system work, control and correspondence with foreign country.
The utility model is mainly applied and is applicable to medical institutions' plasma proteins clinical rapid checking such as hospital, community medicine center.
Above embodiment is only for illustration of preferred implementation of the present utility model; but the utility model is not limited to above-mentioned embodiment; in the ken that described exercising ordinary skill possesses; the any amendment done within spirit of the present utility model and principle, equivalently to substitute and improvement etc., it all should be encompassed within the technical scheme scope of the utility model request protection.
Claims (8)
1. plasma proteins quick analysis system, it is characterized in that: comprise casing, and the built-in Single Chip Microcomputer (SCM) system be arranged in casing, the power-supplying circuit be connected respectively with built-in Single Chip Microcomputer (SCM) system, Quick Response Code read module, laser emitting module, data acquisition circuit, temperature control circuit, clock circuit; Described built-in Single Chip Microcomputer (SCM) system is connected with switched communication interface, touch screen and thermal printer simultaneously.
2. plasma proteins quick analysis system according to claim 1, it is characterized in that: described laser emitting module is connected with geometrical light-path module, geometrical light-path model calling has amplifying circuit, and amplifying circuit is connected with the data acquisition circuit be connected with built-in Single Chip Microcomputer (SCM) system.
3. plasma proteins quick analysis system according to claim 2, is characterized in that: described geometrical light-path module is provided with cuvette.
4. plasma proteins quick analysis system according to claim 1, it is characterized in that: described built-in Single Chip Microcomputer (SCM) system is STC Single Chip Microcomputer (SCM) system, Single Chip Microcomputer (SCM) system adopts STC12C5A60S2 as main control unit, possess single clock, monocyclic ability, arithmetic speed is the twelvefold of common 8051 serial CPU.
5. the plasma proteins quick analysis system according to Claims 2 or 3, it is characterized in that: described geometrical light-path module is disposal molding processing, inside arranges reaction cup room, lasing light emitter room is being set perpendicular to reaction cup chamber axial direction and photoelectricity accepts transducer room, and be path channels between lasing light emitter room and sensor holding chamber, in path channels, optical module is set, reaction cup inductor is set in the bottom of reaction cup room simultaneously.
6. plasma proteins quick analysis system according to claim 1, is characterized in that: described laser emitting module comprises laser tube, constant-current circuit, lens and crystal; Laser tube selects red LD laser parallel light pipe, launches the laser beam of the high depth of parallelism, measures wavelength 650nm; The electric current of the wide region that constant-current circuit provides external power converts the steady current needed for laser tube to, and lens are used for focusing on and expanding, and crystal is used for changing the color of light.
7. plasma proteins quick analysis system according to claim 1, it is characterized in that: described Quick Response Code read module directly reads specific protein matched reagent box Quick Response Code and obtains specific curves, be not used as typical curve, be not used as blank, guarantee reagent and family curve are definitely identical, detect accurately and reliably.
8. plasma proteins quick analysis system according to claim 1, is characterized in that: described temperature control circuit comprises temperature detection and computer heating control two parts; What temperature detection adopted is DB18B20 intelligent temperature sensor, and what device of heating adopted is PTC ceramic heating flake; By being fixed on the temperature sensors in light path module, the working temperature of real-time detecting system, ensures that the testing environment temperature of analyser the best is 37
0c.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420668573.7U CN204177810U (en) | 2014-11-11 | 2014-11-11 | Plasma proteins quick analysis system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420668573.7U CN204177810U (en) | 2014-11-11 | 2014-11-11 | Plasma proteins quick analysis system |
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| Publication Number | Publication Date |
|---|---|
| CN204177810U true CN204177810U (en) | 2015-02-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420668573.7U Expired - Fee Related CN204177810U (en) | 2014-11-11 | 2014-11-11 | Plasma proteins quick analysis system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104914260A (en) * | 2015-05-23 | 2015-09-16 | 深圳德夏生物医学工程有限公司 | Portable biochemistry and special protein analyzer |
| CN112924418A (en) * | 2019-12-05 | 2021-06-08 | 深圳迈瑞生物医疗电子股份有限公司 | Specific protein analysis system |
-
2014
- 2014-11-11 CN CN201420668573.7U patent/CN204177810U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104914260A (en) * | 2015-05-23 | 2015-09-16 | 深圳德夏生物医学工程有限公司 | Portable biochemistry and special protein analyzer |
| CN112924418A (en) * | 2019-12-05 | 2021-06-08 | 深圳迈瑞生物医疗电子股份有限公司 | Specific protein analysis system |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150225 Termination date: 20161111 |