CN207366571U - A kind of gold mark and fluorescence immune chromatography synthesis analyzer - Google Patents
A kind of gold mark and fluorescence immune chromatography synthesis analyzer Download PDFInfo
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- CN207366571U CN207366571U CN201721208151.1U CN201721208151U CN207366571U CN 207366571 U CN207366571 U CN 207366571U CN 201721208151 U CN201721208151 U CN 201721208151U CN 207366571 U CN207366571 U CN 207366571U
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- monochromatic source
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- gold mark
- photoelectric sensor
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Abstract
The utility model belongs to medicine apparatus field, it is related to detection and analysis, especially a kind of gold mark and fluorescence immune chromatography synthesis analyzer, including a photoelectric sensor, the induction end of the photoelectric sensor is set straight down, one group of gold mark monochromatic source is symmetrically installed with positioned at the photoelectric sensor both sides, photoelectric sensor both sides between the two gold medals mark monochromatic source are symmetrically installed with one group of fluorescence monochromatic source, the gold mark monochromatic source uses LED of the wavelength for 520nm, and the fluorescence monochromatic source uses LED of the wavelength for 365nm；The glossing up of the gold mark monochromatic source and fluorescence monochromatic source is rectangle；The signal output part of the photoelectric sensor is connected with central processing module and data storage module.
Description
Technical field
The utility model belongs to medicine apparatus field, is related to detection and analysis, especially a kind of gold mark and fluorescence immune chromatography
Synthesis analyzer.
Background technology
Gold standard chromatography is a kind of common labelling technique, is to resist using colloidal gold as tracer label thing applied to antigen
A kind of new immunolabelling technique of body, have the advantages of it is unique be quick on the draw, specifically, quickly, easy, accuracy rate is high,
Can especially meet quickly to go out inspection result within 10 minutes, Gold standard make chromatography for a kind of method for quickly detecting in medicine
It is widely used in terms of the disease rapid screening of inspection field.
Fluorescence immune chromatography technology, is one kind that immunofluorescence technique and Traditional immunochromatographic technology are combined development innovation
Quantitative new detection technique.The technology is to retain that colloidal gold immunochromatographimethod technical operation is easy, detection is quick, portability is strong excellent
Point is outer, and also strengthening technology by fluorescent tracing realizes the accurate quantification of testing result.This technology and traditional Fast Detection Technique
Performance compares, and has the advantages that sensitivity higher, detection range are wider and cheap.Detection sensitivity is high compared with its colloidal gold method
The 2-3 order of magnitude.The advantages of fluorescence immune chromatography technology is unique be quick on the draw, specifically, quickly, easy, accuracy rate is high, especially
It can meet quickly to go out inspection result within 10 minutes, fluorescence immune chromatography method has been examined as a kind of method for quickly detecting in medicine
The field of testing is widely used.
This two kinds marks and detection device, its structure is similar to include a CCD more, and the both sides of the CCD are symmetrically installed with a LED
Monochromatic source, above-mentioned two LED monochromatic sources, for the test strips correspondence position being radiated in check card, the T in above-mentioned test strips
Line (detection line) and C lines (nature controlling line) are acquired by CCD, judge to treat test sample according to the gray value of collection image afterwards
This yin and yang attribute and concentration of specimens, the wavelength for differing only in monochromatic source of two kinds of detection modes are different.
In practical operation, at present there is certain deficiency in gold mark analyzer in use, have the disadvantage that：
1. two kinds of detection and analysis devices are separate, can not be completed in an equipment, therefore, to be carried out to two ways
Examine respectively, need two kinds of equipment of buying, the inconvenience that can undoubtedly cause the raising of cost and use.
2. the light source that existing two kinds of analytical equipments use is mostly ordinary light source, and the outgoing optical cross-section of ordinary light source is circle
Shape, in verification process, the light which sends can not only be irradiated to the T lines (detection line) or C line (matter of test strips in check card
Control line) on, it can also be irradiated on the shell of check card, the SKIN RETURN light of check card produces CCD the gray value influence of image
Bigger, this make it that the gray value that CCD produces image is locally unstable, is easy to cause the negative inaccurate with positive judgement of sample,
Especially mistake is more easily determined in weakly positive or weak negative sample.
The detection poor repeatability of two kinds of detection and analysis devices of 2.CCD Image Acquisition principles, the position of check card is slightly not
It is same also to influence whether testing result.Therefore some can only be done qualitatively or half with the gold mark analyzer of ccd image acquisition principle
Quantitative detection, it is impossible to do quantitative detection, that is, be only able to detect either with or without a certain material, but this cannot be accurately detected
The content of kind material is how many.
Two kinds of 3.CCD Image Acquisition principles detection and analysis devices are shorter due to being limited its service life be subject to CCD,
It is only 10,000 hours that CCD is limited its service life be subject to the problems such as fever, therefore the service life of gold mark analyzer does not surpass at present
Spend 2 years.
Utility model content
The purpose of the utility model is to overcome the deficiencies in the prior art, there is provided a kind of precision is high, and repeatability is good, uses
One kind gold mark and fluorescence immune chromatography synthesis analyzer of long lifespan.
The purpose of this utility model takes following technical scheme to realize：
A kind of gold mark and fluorescence immune chromatography synthesis analyzer, it is characterised in that：Including a photoelectric sensor, the photoelectricity
The induction end of sensor is set straight down, and one group of gold mark monochromatic source is symmetrically installed with positioned at the photoelectric sensor both sides,
Photoelectric sensor both sides between the two gold medals mark monochromatic source are symmetrically installed with one group of fluorescence monochromatic source, and the gold mark is monochromatic
Light source uses LED of the wavelength for 520nm, and the fluorescence monochromatic source uses LED of the wavelength for 365nm.
Moreover, the light hole of the gold mark monochromatic source and fluorescence monochromatic source is rectangle.
Moreover, the signal output part of the photoelectric sensor is connected with central processing module and data storage module.
The advantages of the utility model and good effect are：
1st, this synthesis analyzer, is separately installed with gold mark two kinds of light of monochromatic source and fluorescence monochromatic source in same device
Source, so that the function that existing gold is marked to chromatograph and fluorescence immune chromatography instrument merges in same equipment, it is rational in infrastructure, effectively
Reduce cost.
2nd, this synthesis analyzer, substitutes CCD using photoelectric sensor, the advantage is that, photoelectric sensor technology is ripe, just
Normal service life can significantly prolong the service life more than 10 years, therefore on the basis of analyser function reservation.Using list
Color light source substitutes ordinary light source, and the light hole of monochromatic source is arranged to rectangle, then adjustable light source exposes to the suitable of test strips
Position is closed, prevents light source from exposing to the shell of check card, effectively avoids interference caused by illumination, improves the precision of detection.
3rd, the signal output part of photoelectric sensor is connected with central processing module and data storage dress in this synthesis analyzer
Put, be then easy to the signal by line array CCD collection to be stored and analyzed.
4th, this synthesis analyzer can be carried out at the same time gold mark chromatography and fluorescence immune chromatography method carries out two kinds of analyses and detection,
Light hole is used effectively to reduce the reflective caused interference of external light source irradiation, lifting inspection as light source for the monochromatic light of rectangle
The precision and repeatability of survey, at the same time, by the mature technology of photoelectric sensor can effective lifting device service life, and
With data storage, the function of analysis, can be used as reference instrument configuration hospital, testing agency and inspection and quarantine station etc.；Can be with
Promote the use of, directly can be quickly carried in medical inspection, scientific research and inspection and quarantine industry as standard method for quickly detecting
For detecting data.
Brief description of the drawings
Fig. 1 is the structure diagram of the utility model；
Fig. 2 is the structure diagram of gold mark monochromatic source and fluorescence monochromatic source in Fig. 1；
Fig. 3 is the structure diagram that the utility model uses process.
Embodiment
The embodiment of the utility model is further described below in conjunction with attached drawing；The present embodiment is descriptive, is not
Limited, it is impossible to thus limit the scope of protection of the utility model.
A kind of gold mark and fluorescence immune chromatography synthesis analyzer, the innovation of the utility model is, including a photoelectric transfer
Sensor 2, the induction end of the photoelectric sensor are set straight down, and one group of gold mark is symmetrically installed with positioned at the photoelectric sensor both sides
Monochromatic source 1, the photoelectric sensor both sides between the two gold medals mark monochromatic source are symmetrically installed with one group of fluorescence monochromatic source
3, the gold mark monochromatic source uses LED of the wavelength for 520nm, and the fluorescence monochromatic source uses LED of the wavelength for 365nm.
In the present embodiment, the glossing up 4 of the gold mark monochromatic source and fluorescence monochromatic source is rectangle.
In the present embodiment, the signal output part of the photoelectric sensor is connected with central processing module and data storage mould
Block.
In the present embodiment, installation temperature capacity checking device can be also aided in, according to the temperature braking correction check number for examining scene
According to.
The operation principle of the utility model is：
When the utility model at work, as shown in figure 3, operating personnel when being detected accordingly, detection card 5 is placed
Below photoelectric sensor so that the test strips 6 in detection card are located at the appropriate sensed position of photoelectric sensor, afterwards according to phase
Corresponding monochromatic source is adjusted irradiating angle by the detection operating personnel answered, its emergent light is incident upon test strips upper surface completely
Suitable position and angle, at this time photoelectric sensor can by test strips reflect light projection to photoelectric sensor induction end, and
The signal output part of photoelectric sensor then can be by the signal output of induction end into central processing module and data storage module.
Above-mentioned central processing module, can use exterior PC, microcontroller or other devices, and data storage module can be independent
In central processing module, can also be installed in central processing module, such as the storage element in PC.Above-mentioned central processing module may be used also
Connect printer or other auxiliary devices.
This synthesis analyzer can be carried out at the same time gold mark chromatography and fluorescence immune chromatography method carries out two kinds of analyses and detection, adopt
The reflective caused interference of external light source irradiation, lifting detection can be effectively reduced by the use of the monochromatic light that glossing up is rectangle as light source
Precision and repeatability, at the same time, by the mature technology of photoelectric sensor can effective lifting device service life, and have
There is data storage, the function of analysis, can be used as reference instrument configuration hospital, testing agency and inspection and quarantine station etc.；It can make
Promote the use of, directly can be quickly provided in medical inspection, scientific research and inspection and quarantine industry for standard method for quickly detecting
Detect data.
Claims (3)
1. a kind of gold mark and fluorescence immune chromatography synthesis analyzer, it is characterised in that：Including a photoelectric sensor, the photoelectric transfer
The induction end of sensor is set straight down, positioned at the photoelectric sensor both sides be symmetrically installed with one group gold mark monochromatic source, with
Photoelectric sensor both sides between the two gold medals mark monochromatic source are symmetrically installed with one group of fluorescence monochromatic source, the gold mark monochromatic light
Source uses LED of the wavelength for 520nm, and the fluorescence monochromatic source uses LED of the wavelength for 365nm.
2. a kind of gold mark according to claim 1 and fluorescence immune chromatography synthesis analyzer, it is characterised in that：The gold mark
The glossing up of monochromatic source and fluorescence monochromatic source is rectangle.
3. a kind of gold mark according to claim 1 and fluorescence immune chromatography synthesis analyzer, it is characterised in that：The photoelectricity
The signal output part of sensor is connected with central processing module and data storage module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721208151.1U CN207366571U (en) | 2017-09-20 | 2017-09-20 | A kind of gold mark and fluorescence immune chromatography synthesis analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721208151.1U CN207366571U (en) | 2017-09-20 | 2017-09-20 | A kind of gold mark and fluorescence immune chromatography synthesis analyzer |
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| Publication Number | Publication Date |
|---|---|
| CN207366571U true CN207366571U (en) | 2018-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201721208151.1U Active CN207366571U (en) | 2017-09-20 | 2017-09-20 | A kind of gold mark and fluorescence immune chromatography synthesis analyzer |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109298179A (en) * | 2018-11-29 | 2019-02-01 | 福州大学 | A kind of immunochromatography detection system and its Background Recognition method |
| CN110187093A (en) * | 2019-06-26 | 2019-08-30 | 上海艾瑞德生物科技有限公司 | A kind of cross-platform detection device detecting fluorescence immunoassay and colloid gold reagent item |
-
2017
- 2017-09-20 CN CN201721208151.1U patent/CN207366571U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109298179A (en) * | 2018-11-29 | 2019-02-01 | 福州大学 | A kind of immunochromatography detection system and its Background Recognition method |
| CN109298179B (en) * | 2018-11-29 | 2023-09-01 | 福州大学 | Immunochromatography detection system and background recognition method thereof |
| CN110187093A (en) * | 2019-06-26 | 2019-08-30 | 上海艾瑞德生物科技有限公司 | A kind of cross-platform detection device detecting fluorescence immunoassay and colloid gold reagent item |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210330 Address after: Room 503, gate 3, block F, Haitai green industrial base, No.6 Haitai development road, Huayuan Industrial Zone, Binhai New Area, Tianjin Patentee after: Puhaoda Biotechnology (Tianjin) Co.,Ltd. Address before: No.52 Jintang road Hedong District Tianjin 300170 Patentee before: TIANJIN RUIZE ANALYTICAL INSTRUMENT Co.,Ltd. |