CN207148123U - A kind of immunofluorescence analysis instrument based on smart mobile phone - Google Patents
A kind of immunofluorescence analysis instrument based on smart mobile phone Download PDFInfo
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- CN207148123U CN207148123U CN201721250915.3U CN201721250915U CN207148123U CN 207148123 U CN207148123 U CN 207148123U CN 201721250915 U CN201721250915 U CN 201721250915U CN 207148123 U CN207148123 U CN 207148123U
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- mobile phone
- filter disc
- fluorescence excitation
- smart mobile
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Abstract
The utility model provides a kind of immunofluorescence analysis instrument based on smart mobile phone, including lucifuge cavity and the fluorescence excitation and transmitting optical module that are arranged at the lucifuge inside cavity；The detection card patchhole that card is detected for inserting is offered close to fluorescence excitation and transmitting optical module one end in lucifuge cavity；And it is provided with lucifuge cavity front for the stable mobile phone stopper slot for placing external smart mobile phone；Fluorescence excitation and transmitting optical module include optics fixed support and are arranged at a pair of fluorescence excitation light sources and exciting light filter disc on the optics fixed support top, the exciting light filter disc is located at fluorescence excitation light source top, in actual use, smart mobile phone is positioned in mobile phone stopper slot, smart mobile phone can carry out detecting the fluoroscopic image collection of card by means of the instrument, and then the albumen detected to Immunofluorescence test paper strip in sample quantifies, and detection process is simple and quick, detection sensitivity is high, the degree of accuracy is high.
Description
[technical field]
Immunofluorescence analysis instrument equipment technical field is the utility model is related to, more particularly to a kind of reasonable in design, behaviour
Facilitate, the immunofluorescence analysis instrument based on smart mobile phone of low manufacture cost.
[background technology]
Real-time test is a segmented industry of in-vitro diagnosis work, and it relies on convenient, quick advantage, may be implemented in patient
Diagnostic result is quickly obtained at one's side, turns into a fast-developing in recent years emerging field, its skill of the foundation currently developed
Art characteristic is mainly divided into the first generation of the three generations based on quick diagnosis test paper such as blood sugar test paper bar, early pregnancy test strips, with
The second generation based on cartridge type nucleic acid amplification, the third generation based on the application of smart mobile phone, compared to preceding two generation, the 3rd
In generation, possesses the quantitative detectability of the special multi-parameter of highly sensitive height due to it and more integrates portable, easy to operate, Yong Huyou
Many potential advantages such as good, it has also become the forefront technology of external detection field immediately.
Immunofluorescence analysis technology is the accurate immune labeled detection technique that new development is got up, with traditional enzyme linked immunological
Method and Gold standard are compared, and immunofluorescence analysis sensitivity is high, and high specificity is easy to operate, without radioactive substance conduct
Label, thus with "dead", label it is stable, be easy to long-term preservation, test repeatability is good, analyze speed is fast, sample
Dosage is few and the advantages that standard curve broad quantum, after the XRF light of certain frequency that has been measure material absorbing, material
, there is proportional relation in the intensity of light itself launched, can be by determining the light of fluorescence between the intensity and amount of material of fluorescence
Spectrum and fluorescence intensity, qualitative or quantitative analysis is carried out to material, and immunofluorescence analysis technology is in current biomedical inspection
Conventional quick analytical technology, microorganism, viral antigen or antibody test, hormone test, tumor-marker analyte detection, cell because
The fields such as son detection have broad application prospects.
The diagnostic biomarkers clinically commonly used at present, detection method such as chemiluminescence, El isa quantitative determination process, no
The determination methods such as the quick and convenient use of energy, the collaurum of fast diagnosis reagent are not easily achieved quantitative determination, and these detection reagents are being cured
Operated with institute by professional, in the prior art without easy, quick, be suitable for detection reagent that household person uses and
Instrument, it can be seen that, the Immunofluorescence test instrument of Quantitative detection a kind of can be invented, make its can each hospital emergency treatment and
Applied in the intracardiac professional section office of grade, facilitate patient and the household person of friend's person in middle and old age health prevention to use again, while can pass through
Testing result is transferred to the family doctor or specialist of user by client, so that medical professional is possible to for those
The patient that acute disease occurs provides prevention, health care, urgent see a doctor guidance and Treatment monitoring, turns into those skilled in the art's letter and waits to solve
Technical barrier certainly.
[utility model content]
To overcome the problems of prior art, the utility model provides a kind of reasonable in design, operation facility, system
Make the low immunofluorescence analysis instrument based on smart mobile phone of cost.
The scheme that the utility model solves technical problem is to provide a kind of immunofluorescence analysis instrument based on smart mobile phone, wraps
Include lucifuge cavity and be arranged at the fluorescence excitation and transmitting optical module of the lucifuge inside cavity；Leaned in the lucifuge cavity
Nearly fluorescence excitation and transmitting optical module one end offers the detection card patchhole for inserting detection card；And in lucifuge chamber
Body front is provided with for the stable mobile phone stopper slot for placing external smart mobile phone, on the mobile phone stopper slot and fluorescence excitation
Light hole is offered with transmitting optical module corresponding position；The fluorescence excitation and transmitting optical module include optics fixed support
And a pair of fluorescence excitation light sources and exciting light filter disc on the optics fixed support top are arranged at, the exciting light filter disc is positioned at glimmering
Phot-luminescence source top, and two groups of fluorescence excitation light sources and exciting light filter disc middle part are provided with transmitting light filter disc, the light
Learn fixed support and through hole is opened up at transmitting light filter disc position, transmitting light filter disc is arranged in the through hole.
Preferably, the lucifuge cavity includes lower chamber and the upper cavity being flexibly connected with lower chamber；The lower chamber is in L
Type moulding；And several threaded connection holes are offered in upper cavity.
Preferably, the fluorescence excitation light source is light emitting diode.
Preferably, the optics fixed support of the fluorescence excitation and transmitting optical module is correspondingly arranged with upper cavity, and light
Learn through hole and the positive light hole position correspondence of lucifuge cavity that fixed support opens up at transmitting light filter disc position.
Preferably, the exciting light filter disc that the transmitting light filter disc both sides are set is with launching light filter disc into 120-160 degree angles
Set.
Preferably, the optics fixed support top, which is integrally formed, is provided with for placing fluorescence excitation light source, exciting light
Filter disc and the boss for launching light filter disc；Transmitting light filter disc is located at the centre of boss；It is and simultaneously upward at the boss both ends
Extend shape identical fluorescence excitation erecting bed, fluorescence excitation light source, exciting light filter disc are all arranged at fluorescence excitation installation
On platform.
Preferably, the lower chamber is internally provided with threaded post corresponding with each threaded connection hole.
Preferably, the fluorescence excitation and transmitting optical module engaging are arranged at lucifuge inside cavity.
Compared with prior art, a kind of immunofluorescence analysis instrument based on smart mobile phone of the utility model is by setting simultaneously
Lucifuge cavity 15 and the fluorescence excitation being arranged inside the lucifuge cavity 15 and transmitting optical module 17, and in lucifuge cavity
15 fronts are provided for the stable mobile phone stopper slot 111 for placing external smart mobile phone, with reference to fluorescence excitation and transmitting optical module
17 concrete structure design, as fluorescence excitation and transmitting optical module 17 including optics fixed support 171 and are arranged at the light
A pair of fluorescence excitation light sources (176,177) and exciting light filter disc (174,175) on the top of fixed support 171 are learned, were actually used
Cheng Zhong, smart mobile phone is positioned in mobile phone stopper slot 111, smart mobile phone can carry out detecting the fluorescence of card by means of the instrument
IMAQ, and then the albumen detected to Immunofluorescence test paper strip in sample quantifies, and detection process is simple and quick,
Detection sensitivity is high, the degree of accuracy is high.
[brief description of the drawings]
Fig. 1 is a kind of stereoscopic-state structural representation of the immunofluorescence analysis instrument based on smart mobile phone of the utility model.
Fig. 2 is a kind of explosive state structural representation of the immunofluorescence analysis instrument based on smart mobile phone of the utility model.
Fig. 3 is fluorescence excitation and transmitting optics group in a kind of immunofluorescence analysis instrument based on smart mobile phone of the utility model
The stereoscopic-state structural representation of part.
[embodiment]
To make the purpose of this utility model, technical scheme and advantage are more clearly understood, below in conjunction with drawings and Examples,
The utility model is further elaborated.It should be appreciated that specific embodiment described herein is used only for explaining this
Utility model, it is not used to limit this utility model.
Fig. 1 to Fig. 3 is referred to, a kind of immunofluorescence analysis instrument 1 based on smart mobile phone of the utility model includes lucifuge chamber
Body 15 and the fluorescence excitation being arranged inside the lucifuge cavity 15 and transmitting optical module 17；Leaned in the lucifuge cavity 15
Nearly fluorescence excitation and transmitting optical module 17 one end offers the detection card patchhole for inserting detection card 13；And keeping away
The front of optical cavity body 15 is provided with the mobile phone stopper slot 111 for stable placement external smart mobile phone, on the mobile phone stopper slot 11,
Light hole 113 is offered with fluorescence excitation and the transmitting corresponding position of optical module 17；The fluorescence excitation and transmitting optical module
17 include optics fixed support 171 and be arranged at the top of optics fixed support 171 a pair of fluorescence excitation light sources (176,
177) and exciting light filter disc (174,175), the exciting light filter disc (174,175) are located at fluorescence excitation light source (176,177) top,
And two groups of fluorescence excitation light sources (176,177) and exciting light filter disc (174,175) middle part are provided with transmitting light filter disc
1731, the optics fixed support 171 opens up through hole at transmitting light filter disc 1731 position, and transmitting light filter disc 1731 is arranged at the through hole
In.
By setting lucifuge cavity 15 and the fluorescence excitation being arranged inside the lucifuge cavity 15 and transmitting light simultaneously
Component 17 is learned, and the stable mobile phone stopper slot 111 for placing external smart mobile phone is provided in the front of lucifuge cavity 15, with reference to glimmering
Light excites and launched the concrete structure design of optical module 17, as fluorescence excitation and transmitting optical module 17 include optics and fix branch
Frame 171 and a pair of the fluorescence excitation light sources (176,177) and exciting light filter disc for being arranged at the top of optics fixed support 171
(174,175), in actual use, smart mobile phone is positioned in mobile phone stopper slot 111, smart mobile phone can be by means of this
Instrument detect the fluoroscopic image collection of card, and then the albumen detected to Immunofluorescence test paper strip in sample quantifies,
And detection process is simple and quick, detection sensitivity is high, the degree of accuracy is high.
Preferably, the lucifuge cavity 15 includes lower chamber and the upper cavity 11 being flexibly connected with lower chamber；The cavity of resorption
The L-shaped moulding of body；And several threaded connection holes are offered in upper cavity 11.It is reasonable in design.It can guarantee that fluorescence excitation
The emergent light of light source (176,177) and the fluorescence being excited pass through, and isolation is except the outgoing of fluorescence excitation light source (176,177)
Interference light outside light and the fluorescence being excited, the signal to noise ratio of fluorescence imaging is improved, ensure the sensitivity of testing result and accurate
Degree.
Preferably, the fluorescence excitation light source (176,177) is light emitting diode.Light emitting diode is area source.Using
After this structure, formation light intensity is sufficiently strong on particular excitation face, irradiated area is sufficiently large, light distribution is sufficiently uniform excites
Light, avoid discrete multiple shooting on group light source such as annular array of light sources and bring because position, luminous efficiency and work shape
The differences such as state cause excitation line light distribution it is uneven with it is uncontrollable.
Preferably, the optics fixed support 171 of the fluorescence excitation and transmitting optical module 17 is corresponding with upper cavity 11 sets
Put, and the through hole and the positive light hole 113 of lucifuge cavity 15 that optics fixed support 171 opens up at transmitting light filter disc 1731 position
Position correspondence.It is reasonable in design.
Preferably, the exciting light filter disc (174,175) and transmitting light filter disc that the both sides of transmitting light filter disc 1731 are set
1731 are set into 120-160 degree angle.Simple in construction after this structure, easy to operate, can send can excite fluorescence
The light of specific wavelength.
Preferably, the top of optics fixed support 171 be integrally formed be provided with for place fluorescence excitation light source (176,
177), the boss 173 of exciting light filter disc (174,175) and transmitting light filter disc 1731；Transmitting light filter disc 1731 is located at boss 173
Centre；And shape identical fluorescence excitation erecting bed 1733 is extended upward simultaneously at the both ends of boss 173, fluorescence swashs
Light emitting source (176,177), exciting light filter disc (174,175) are all arranged on the fluorescence excitation erecting bed 1733.
Preferably, the lower chamber is internally provided with threaded post corresponding with each threaded connection hole.
Preferably, the fluorescence excitation and the transmitting engaging of optical module 17 are arranged inside lucifuge cavity 15.
Principle of the present utility model is：
Smart mobile phone is placed on the design Immunofluorescence test instrument, and camera is directed at the mobile lens hole position of instrument, inspection
Survey the detection screens of card inserting instrument.With high brightness light emitting diode transmitting exciting light by exciting light filter disc (174,
175) filter, the fluorescent dye in the exciting light irradiating and detecting card excites fluorescence, and fluorescence launches light filter disc along straight-line pass
1731, in the sensor for the camera for being collected into smart mobile phone, so as to produce real-time fluoroscopic image.
The real-time fluorescence image collected, which both may be displayed on the display screen of smart mobile phone, carries out direct interpretation and analysis,
It can also be stored in the built-in memory cell of smart mobile phone by cable transmission to the server for being provided with image analysis software
Analyzed and processed on computer, can also by wireless signal, be real-time transmitted to carried out on the corresponding webserver it is long-range
On-line analysis.After this structure so that testing result is intuitively visual, makes full use of smart mobile phone, the design is simple in construction,
Compact, it can be applied to that portable set, testing result are directly perceived visual, make full use of smart mobile phone.
Compared with prior art, a kind of immunofluorescence analysis instrument 1 based on smart mobile phone of the utility model is by setting simultaneously
Lucifuge cavity 15 and the fluorescence excitation being arranged inside the lucifuge cavity 15 and transmitting optical module 17 are put, and in lucifuge chamber
The front of body 15 is provided for the stable mobile phone stopper slot 111 for placing external smart mobile phone, with reference to fluorescence excitation and transmitting optics group
The concrete structure design of part 17, as fluorescence excitation and transmitting optical module 17 including optics fixed support 171 and are arranged at this
A pair of fluorescence excitation light sources (176,177) and exciting light filter disc (174,175) on the top of optics fixed support 171, actual use
During, smart mobile phone is positioned in mobile phone stopper slot 111, smart mobile phone can carry out detecting the glimmering of card by means of the instrument
Light image gathers, and then the albumen detected to Immunofluorescence test paper strip in sample quantifies, and detection process is simply fast
Speed, detection sensitivity is high, the degree of accuracy is high.
Above-described the utility model embodiment, does not form the restriction to scope of protection of the utility model.It is any
Made within spirit of the present utility model and principle modifications, equivalent substitutions and improvements etc., should be included in the utility model
Claims within.
Claims (8)
- A kind of 1. immunofluorescence analysis instrument based on smart mobile phone, it is characterised in that：Including lucifuge cavity and it is arranged at described The fluorescence excitation and transmitting optical module of lucifuge inside cavity；In the lucifuge cavity close to fluorescence excitation and transmitting optical module One end offers the detection card patchhole for inserting detection card；And it is provided with lucifuge cavity front and is placed for stable The mobile phone stopper slot of external smart mobile phone, opened on the mobile phone stopper slot, with fluorescence excitation and transmitting optical module corresponding position Provided with light hole；The fluorescence excitation and transmitting optical module include optics fixed support and are arranged at the optics fixed support A pair of fluorescence excitation light sources and exciting light filter disc on top, the exciting light filter disc are located at fluorescence excitation light source top, and at two groups Fluorescence excitation light source and exciting light filter disc middle part are provided with transmitting light filter disc, and the optics fixed support is in transmitting light filter disc portion Position opens up through hole, and transmitting light filter disc is arranged in the through hole.
- A kind of 2. immunofluorescence analysis instrument based on smart mobile phone as claimed in claim 1, it is characterised in that：The lucifuge chamber Body includes lower chamber and the upper cavity being flexibly connected with lower chamber；The L-shaped moulding of the lower chamber；And offered in upper cavity Several threaded connection holes.
- A kind of 3. immunofluorescence analysis instrument based on smart mobile phone as claimed in claim 1, it is characterised in that：The fluorescence swashs Light emitting source is light emitting diode.
- A kind of 4. immunofluorescence analysis instrument based on smart mobile phone as claimed in claim 2, it is characterised in that：The fluorescence swashs The optics fixed support of hair and transmitting optical module is correspondingly arranged with upper cavity, and optics fixed support is at transmitting light filter disc position The through hole opened up and the positive light hole position correspondence of lucifuge cavity.
- A kind of 5. immunofluorescence analysis instrument based on smart mobile phone as described in claim 1 or 4, it is characterised in that：The hair The exciting light filter disc for penetrating the setting of light filter disc both sides is set with transmitting light filter disc into 120-160 degree angle.
- A kind of 6. immunofluorescence analysis instrument based on smart mobile phone as claimed in claim 1, it is characterised in that：The optics is consolidated Fixed rack top, which is integrally formed, to be provided with for placing fluorescence excitation light source, exciting light filter disc and the boss for launching light filter disc； Transmitting light filter disc is located at the centre of boss；And shape identical fluorescence excitation peace is extended upward simultaneously at the boss both ends Platform is filled, fluorescence excitation light source, exciting light filter disc are all arranged on the fluorescence excitation erecting bed.
- A kind of 7. immunofluorescence analysis instrument based on smart mobile phone as claimed in claim 2, it is characterised in that：The lower chamber It is internally provided with threaded post corresponding with each threaded connection hole.
- A kind of 8. immunofluorescence analysis instrument based on smart mobile phone as claimed in claim 1, it is characterised in that：The fluorescence swashs Hair and transmitting optical module engaging are arranged at lucifuge inside cavity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721250915.3U CN207148123U (en) | 2017-09-27 | 2017-09-27 | A kind of immunofluorescence analysis instrument based on smart mobile phone |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721250915.3U CN207148123U (en) | 2017-09-27 | 2017-09-27 | A kind of immunofluorescence analysis instrument based on smart mobile phone |
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| CN207148123U true CN207148123U (en) | 2018-03-27 |
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| CN201721250915.3U Active CN207148123U (en) | 2017-09-27 | 2017-09-27 | A kind of immunofluorescence analysis instrument based on smart mobile phone |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109856100A (en) * | 2019-03-22 | 2019-06-07 | 格瑞复斯（武汉）生化科技股份有限公司 | A kind of device acquiring western blot fluorescence signal |
| CN116539581A (en) * | 2023-05-24 | 2023-08-04 | 宁波大学 | Fluorescent detection box and use method |
-
2017
- 2017-09-27 CN CN201721250915.3U patent/CN207148123U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109856100A (en) * | 2019-03-22 | 2019-06-07 | 格瑞复斯（武汉）生化科技股份有限公司 | A kind of device acquiring western blot fluorescence signal |
| CN116539581A (en) * | 2023-05-24 | 2023-08-04 | 宁波大学 | Fluorescent detection box and use method |
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