CN206362811U - A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus - Google Patents

A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus Download PDF

Info

Publication number
CN206362811U
CN206362811U CN201621332670.4U CN201621332670U CN206362811U CN 206362811 U CN206362811 U CN 206362811U CN 201621332670 U CN201621332670 U CN 201621332670U CN 206362811 U CN206362811 U CN 206362811U
Authority
CN
China
Prior art keywords
quantitative
sample
automatic
electrophoresis apparatus
proportional valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201621332670.4U
Other languages
Chinese (zh)
Inventor
阎超
姚冬
李亚珍
李静
孙淑军
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Tong Micro Analysis Technology Co ltd
Original Assignee
Shanghai Tong Micro Analysis Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Tong Micro Analysis Technology Co ltd filed Critical Shanghai Tong Micro Analysis Technology Co ltd
Priority to CN201621332670.4U priority Critical patent/CN206362811U/en
Application granted granted Critical
Publication of CN206362811U publication Critical patent/CN206362811U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Sampling And Sample Adjustment (AREA)

Abstract

A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus, is connected with quantitative capillary tube electrophoresis apparatus, including nanoliter level proportional valve, automatic soda acid activation/cleaning device, be electrically isolated groove post on power-up device, automatic sampling stream and sample tray;Wherein, nanoliter level proportional valve is used to realize nanoliter level accurate quantitative analysis sample introduction, it is made up of rotatable built-in quantitative loop and the fixation outer shroud with four fixed ports, automatic soda acid activation/cleaning device is used for the activation and cleaning for the separation capillary column for realizing quantitative capillary tube electrophoresis apparatus, include six end liquid distributors, separator tube and syringe pump, some sample bottles are placed with sample tray, automatic sampling stream is used to extract sample, including sampling probe, rinse bath, reagent bottle, external four connectors and additional constant flow pump, being electrically isolated power-up device on groove post includes being electrically isolated groove, separation capillary column is connected with nanoliter level proportional valve and realizes that power-up forms high voltage electric field on post through the electric isolution groove.The utility model has the advantages that favorable reproducibility, precision are high, discriminate against and cross pollution without component.

Description

A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus
Technical field
The utility model is related to a kind of test device, and in particular to a kind of auto injection for quantitative capillary tube electrophoresis apparatus Device, belongs to analysis and testing technology field.
Background technology
Capillary Electrophoresis (CE) is also known as HPCE, is developed after modern efficient liquid chromatography technology A kind of new and effective isolation technics come.CE because of it efficiently, more than quick, low cost, operator scheme and the advantages of being easy to switching, It is widely used in terms of separate analytical technique field, such as environmental protection, Pharmaceutical Analysis, life science and food security.However, CE market approval rate is actually all the time not as good as high performance liquid chromatography (HPLC), and its main cause is the sample injection method of CE " dipping " In the presence of many defects, thus cause quantitatively to be forbidden, the deficiency such as poor accuracy.
CE input modes mainly include two kinds of electromigration injection and hydrodynamics sample introduction, and the former is former according to electrophoresis and EOF Reason and it is commonly used.Because sample each component has different electrophoretic mobilities, the matter that the big component of mobility enters in capillary Smaller than the mobility component of amount is more, therefore causes a greatest drawback of electromigration injection to be to produce component to different charged species Discriminate against.The sample size size of hydrodynamics input mode be by change capillary pass in and out two mouths of pipe between potential difference or pressure difference with And action time is realized.But the size of pressure is influenceed by temperature and mechanical strength, it is difficult to accurate control, this can cause into The accuracy and reappearance of sample be not high.In addition, above-mentioned sample injection method be both needed to by capillary end sample and buffer solution it Between switch movement, easily cause cross pollution and can not continuously be analyzed, it is often more important that can not accurately know sample size, this Showed inferiority entirely in quantitative analysis field.
Utility model content
Technical problem to be solved in the utility model is on the basis of existing HPLC automatic sampler technology, to draw Enter nanoliter level proportional valve and be electrically isolated electricity applying system being used for calmly there is provided a kind of achievable nanoliter level accurate quantitative analysis sample introduction on groove post The automatic sampler of HPCE is measured, HPCE is realized high-precision quantitative sample introduction, favorable reproducibility;Can continuously it exist Line analysis, without power-off, reduces error;Eliminate the discrimination and cross pollution between different sample components.
The scheme that the utility model solves its technical problem is as follows:
A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus, is connected with the quantitative capillary tube electrophoresis apparatus, and this is determined HPCE is measured provided with separation capillary column, it is characterised in that:The automatic sampler includes nanoliter level proportional valve, automatic Power-up device, automatic sampling stream and sample tray in soda acid activation/cleaning device, electric isolution groove post;
The nanoliter level proportional valve is used to realize nanoliter level accurate quantitative analysis sample introduction, by a rotatable built-in quantitative loop and Fixation outer shroud composition with four fixed ports, the built-in quantitative loop, which is internally provided with a sample introduction path and one, to be had accurately admittedly The load path of constant volume, with the rotation of the built-in quantitative loop, the sample introduction path and load path and four fixing ends Mouth switches over connection;
The automatic soda acid activation/cleaning device is used for the activation and cleaning for realizing the separation capillary column, includes Six end liquid distributors, separator tube and syringe pump, six end liquid distributor have an entrance and can be with the entrances Six distribution outlets of connection are changed in turn, wherein, entrance connects one end of the separator tube, and a distribution outlet connection is described One fixed port of nanoliter level proportional valve, three distribution outlets connect three and are equipped with to clean and balance the separation respectively The washer bottle of the different reagents of capillary column, the syringe pump, which is furnished with, allows hand over three ends point for completing exhaust and cleaning function With valve, three valve interfaces of the three ends distributing valve connect automatic sampler washer bottle, automatic sampler waste liquid bottle and described respectively Separator tube, exhaust and cleaning function are completed to switch;
Some sample bottles are placed with the sample tray;
The automatic sampling stream is used to extract sample, including sampling probe, rinse bath, reagent bottle, external four connectors With additional constant flow pump, the sampling probe allows hand over the insertion sample bottle to extract sample and the rinse bath to complete to this The cleaning of sampling probe, the ports of external four connectors connect respectively a fixed port of the nanoliter level proportional valve, One distribution outlet of six end liquid distributor and the additional constant flow pump;
Power-up device includes being electrically isolated groove, the separation capillary of the quantitative capillary tube electrophoresis apparatus on the electric isolution groove post Post is connected with a fixed port of the nanoliter level proportional valve, and realizes that power-up forms high on post through the electric isolution groove Piezoelectric field.
Further, described electric isolution groove is supported on electric isolution groove support, and the electric isolution groove support is fixed on described On the upper lid of automatic sampler.
Further, three described washer bottles are respectively provided with the HCl or NaOH solution of suitable concentration.
Further, described automatic sampler is by automated software control, realizes nanoliter level quantitative sample injection and activation/clear Wash the function of the separation capillary column.
Compared with prior art, effect of the present utility model is:
1. the input mode using unique nanoliter level proportional valve has evaded conventional capillary electrophoresis tube input mode (electromigration Sample introduction, hydrodynamics sample introduction) deficiency, have the advantages that low sample size, favorable reproducibility, precision are high;
2. described in automatic sampler can whole on-line analysis detection, it is to avoid component is discriminated against and cross-contamination phenomena;
3. the utility model realizes full-automation, convenience simple to operation is detected rapidly and efficiently.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model.
Fig. 2 is one of course of work schematic diagram of the present utility model.
Fig. 3 is the two of course of work schematic diagram of the present utility model.
Fig. 4 is the three of course of work schematic diagram of the present utility model.
Fig. 5 is the four of course of work schematic diagram of the present utility model.
In figure,
1 nanoliter level proportional valve, 2 separation capillary columns, 3 external four connectors, 4 six end liquid distributors, 5 sampling probes, 6 Washer bottle, 7 washer bottles, 8 washer bottles, 9 syringe pumps, 10 separator tubes, 11 3 end distributing valves, 12 automatic sampler washer bottles, 13 Automatic sampler waste liquid bottle, 14 first distribution outlets, 15 second distribution outlets, 16 the 3rd distribution outlets, 17 the 4th distribution outlets, 18 the 5th distribution outlets, 19 the 6th distribution outlets, 20. sample trays, 21 reagent bottles, 22 rinse baths, 23 additional constant flow pumps, 24 electricity Isolation channel, 25 load paths, 26 sample introduction paths, 27 are electrically isolated groove support.
Embodiment
The utility model is described in detail below in conjunction with the accompanying drawings, it is still, described here of the present utility model specific Embodiment is only used for explaining the purpose of this utility model, all according to this explanation not for limiting scope of the present utility model Equivalence changes and modification that the content of book is made, are regarded as the claimed scope of the utility model patent application.
Referring to Fig. 1, the automatic sampler described in the utility model for quantitative capillary tube electrophoresis apparatus and quantitative capillary The connection of electrophoresis tube instrument is used, and nanoliter level accurate quantitative analysis sample introduction can be achieved, the quantitative capillary tube electrophoresis apparatus is provided with separation capillary column 2。
The automatic sampler on nanoliter level proportional valve 1, automatic soda acid activation/cleaning device, electric isolution groove post including adding Electric installation, automatic sampling stream and sample tray 20.
The nanoliter level proportional valve 1 is that 2 nanoliters of cuts to hundreds of nanoliters of a variety of different sizes through laser ablation are determined Ring is measured, for realizing nanoliter level accurate quantitative analysis sample introduction;The nanoliter level proportional valve 1 is by a rotatable built-in quantitative loop and has The fixation outer shroud composition of four fixed ports;The built-in quantitative loop, which is internally provided with a sample introduction path 26 and one, has accurate fix The load path 25 of volume, wherein load path 25 realize sample accurate quantification, and sample introduction path 26 realizes that sample detection is analyzed.Institute Four fixed ports are stated respectively with separating capillary column 2, a port of external four connectors 3, six end liquid distributors 4 6th distribution outlet 19 is connected with sampling probe 5.With the rotation of the built-in quantitative loop, the sample introduction path 26 and load path 25 with Four fixed ports of the fixed outer shroud switch over connection.
The automatic soda acid activation/cleaning device is used for the activation and cleaning for realizing the separation capillary column 2.This is automatic Soda acid activation/cleaning device includes six end liquid distributors 4, separator tube 10 and syringe pump 9.Six end liquid distributor 4 have an entrance and can change six distribution outlets being connected in turn with the entrance:First distribution outlet 14, second is distributed The distribution outlet 18 of the 16, the 4th distribution outlet of the distribution outlet of outlet the 15, the 3rd the 17, the 5th and the 6th distribution outlet 19;Wherein, entrance One end of the separator tube 10 is connected, first distribution outlet the 14, second distribution outlet 15 and the 3rd distribution outlet 16 are connected respectively Three washer bottles 6,7 and 8, the washer bottle 6,7 and 8 is respectively provided with the HCl of suitable concentration or the different reagents of NaOH solution, is used to The separation capillary column 2 is activated and cleans, and pipeline is the capillary column dedicated line accurately determined, the 4th distribution outlet 17 Waste liquid end is connected, a port of external four connectors 3 of connection of the 5th distribution outlet 18, the connection of the 6th distribution outlet 19 is described One fixed port of nanoliter level proportional valve 1.The syringe pump 9 is furnished with three end distributing valves 11, the three of the three ends distributing valve 11 Individual valve interface connects automatic sampler washer bottle 12, automatic sampler waste liquid bottle 13 and the separator tube 10 respectively, to switch Complete exhaust and cleaning function.
The sample tray 20 is placed with the sample equipped with different samples containing 84 sample bottle positions and 3 reagent bottle positions Bottle, the sample tray 20 is once fully loaded with sustainable operation more than 14 hours (being free of the scavenging period between sample), easily full The foot experimental work of one day.
The automatic sampling stream is used to extract sample, including sampling probe 5, rinse bath 22, reagent bottle 21, external four leads to Connect device 3 and additional constant flow pump 23.The sampling probe 5, which has, punctures function, can be inserted with the switching of XYZ tendencies the sample bottle with Sample and the rinse bath is extracted to complete the cleaning to the outer wall and inwall of the sampling probe 5.External four connectors 3 Port connects the 5th distribution outlet of a fixed port of the nanoliter level proportional valve 1, six end liquid distributor 4 respectively 18 and the additional constant flow pump 23.The external constant flow pump 23 provides the power of a mitigation, promotes sample from sample introduction path 26 Into in separation capillary column 2.
Power-up device is located at the rear end of nanoliter level proportional valve 1 on the electric isolution groove post, separates the front end of capillary column 2, And be connected with the nanoliter level proportional valve 1.Power-up device includes being electrically isolated groove 24 and is electrically isolated groove support 27 on the electric isolution groove post, The separation capillary column 2 of the quantitative capillary tube electrophoresis apparatus is connected with a fixed port of the nanoliter level proportional valve 1, leads to The nanoliter level proportional valve 1 is crossed to realize after accurate quantitative sample injection, it is ingenious to be achieved through the electric isolution groove 24 for being inserted with electrode Powered up in entrance newel post, with port of export high pressure formation path, high voltage electric field is formed in the separation capillary column 2.Described electricity Isolation channel 24 has conductive not drain characteristic, realizes the separation capillary column 2 and is powered up on post, has overturned conventional capillary electricity Instrument two end electrodes of swimming insert the pattern that two surge flasks realize power-up.Described electric isolution groove 24 is supported in electric isolution groove support 27 On, fallen damage separation capillary column 2 to prevent being electrically isolated groove 24, the electric isolution groove support 27 is fixed on the automatic sampler On upper lid.
The automatic sampler introduces nanoliter level proportional valve 1, automatic soda acid activation/cleaning device and is electrically isolated on groove post Any one in power-up device or two or three of device.
Described automatic sampler is realized and divided described in nanoliter level quantitative sample injection and activation/cleaning by automated software control From the function of capillary column 2.
The operation principle of automatic sampler described in the utility model is as follows:
First, cleaning, exhaust process, referring to Fig. 2.The entrance of six end liquid distributor 4 and the 5th distribution outlet 18 Connection, the nanoliter level proportional valve 1 is in sample introduction path 26, under the effect of syringe pump 9, in automatic sampler washer bottle 12 Cleaning fluid is extracted, separator tube 10 and external four connectors 3 is flowed through, into nanoliter level proportional valve 1, separation capillary column 2 is flowed through To the port of export, the exhaust and cleaning of pipeline are completed.
Secondly, sampling process, referring to Fig. 3.The built-in quantitative loop of the nanoliter level proportional valve 1 rotates 180 °, switches it To load path 25, first movement is inserted into reagent bottle 21 sampling probe 5, and a certain amount of buffer solution is sucked under the effect of syringe pump 9, Then sampling probe 5 is moved to sample tray 20, draws a certain amount of sample, movement is inserted into reagent bottle 21 to last sampling probe 5 again, Draw a certain amount of buffer solution.During this sample introduction, amount of buffer and sample size make sample coat completely just by programme-control And full load path 25 is filled, and this sample introduction process dramatically reduces amount of samples.
Then, sample introduction process, referring to Fig. 4.The built-in quantitative loop of the nanoliter level proportional valve 1 rotates 180 °, switch into Sample path 26.The sample for being stored in built-in quantitative loop is pushed into separation capillary column 2 in the presence of additional constant flow pump 23, by electricity Isolation channel 24, realizes and is powered up on post, under electric field and the double reaction plus of additional constant flow pump 23, realizes and separates and pass through external detection Device detection, computer digital animation software are acquired, analyzed.At the same time, built-in quantitative loop rotates 180 °, is switched to again Load path 25;Sampling probe 5 is moved in rinse bath 22, in the presence of syringe pump 9, and sampling probe 5 enters in rinse bath 22 Row cleaning.
Finally, complete after electrophoretic analysis, separation capillary column 2 must be cleaned, balanced, referring to Fig. 5.The first step, it is described The entrance of six end liquid distributors 4 is connected with the first distribution outlet 14.Will be clear in washer bottle 6 in the presence of syringe pump 9 Washing lotion sucks separator tube 10;The conversion of six end liquid distributor 4 is connected to the 5th distribution outlet 18, the syringe pump 9 By the cleaning fluid push-in nanoliter level proportional valve 1 in separator tube 10 and into separating in capillary column 2, complete to separation capillary column HCl cleanings and the balance of 2 suitable concentration;Second step, the entrance of six end liquid distributor 4 and the second distribution outlet 15 connect It is logical.The cleaning fluid in washer bottle 7 is sucked into separator tube 10 in the presence of syringe pump 9;Six end liquid distributor 4 is changed Connected to the 5th distribution outlet 18, the cleaning fluid in separator tube 10 is pushed into nanoliter level proportional valve 1 and gone forward side by side by the syringe pump 9 Enter to separate in capillary column 2, complete the NaOH cleanings of the high concentration to separating capillary column 2 and balance;3rd step, six end The entrance of liquid distributor 4 is connected with the 3rd distribution outlet 16.The reagent in washer bottle 8 is inhaled in the presence of syringe pump 9 Enter separator tube 10;The conversion of six end liquid distributor 4 is connected to the 5th distribution outlet 18, and the syringe pump 9 will be buffered Cleaning fluid in pipe 10 is pushed into nanoliter level proportional valve 1 and entered in separation capillary column 2, completes to the low of separation capillary column 2 NaOH cleanings and the balance of concentration.
The automatic sampler recovers to original state, the separation analysis of the standby next sample of preparation.
In the above-mentioned course of work, the function of all components of automatic sampler is realized entirely certainly by computer control Dynamic operation.

Claims (4)

1. a kind of automatic sampler for quantitative capillary tube electrophoresis apparatus, is connected with the quantitative capillary tube electrophoresis apparatus, this is quantified HPCE is provided with separation capillary column, it is characterised in that:The automatic sampler includes nanoliter level proportional valve, automatic acid Power-up device, automatic sampling stream and sample tray in alkali activation/cleaning device, electric isolution groove post;
The nanoliter level proportional valve is used to realize nanoliter level accurate quantitative analysis sample introduction, by a rotatable built-in quantitative loop and has The fixation outer shroud composition of four fixed ports, the built-in quantitative loop, which is internally provided with a sample introduction path and one, has accurate fixed appearance Long-pending load path, with the rotation of the built-in quantitative loop, the sample introduction path and load path are entered with four fixed ports Row is switched on;
The automatic soda acid activation/cleaning device is used for the activation and cleaning for realizing the separation capillary column, includes six ends Liquid distributor, separator tube and syringe pump, six end liquid distributor have an entrance and can be with the entrances in turn Six distribution outlets of conversion connection, wherein, entrance connects one end of the separator tube, described nanoliter of a distribution outlet connection One fixed port of level proportional valve, three distribution outlets connect three and are equipped with to clean and balance the separation capillary respectively The washer bottle of the different reagents of tubing string, the syringe pump, which is furnished with, allows hand over the three ends distribution for completing exhaust and cleaning function Valve, three valve interfaces of the three ends distributing valve connect automatic sampler washer bottle, automatic sampler waste liquid bottle and described slow respectively Washing pipe, exhaust and cleaning function are completed to switch;
Some sample bottles are placed with the sample tray;
The automatic sampling stream is used to extract sample, including sampling probe, rinse bath, reagent bottle, external four connectors and outer Plus constant flow pump, the sampling probe, which is allowed hand over, to be inserted the sample bottle to extract sample and the rinse bath to complete to the sampling The cleaning of pin, the ports of external four connectors connects a fixed port of the nanoliter level proportional valve respectively, described One distribution outlet of six end liquid distributors and the additional constant flow pump;
It is described electric isolution groove post on power-up device include be electrically isolated groove, the separation capillary column of the quantitative capillary tube electrophoresis apparatus with One fixed port of the nanoliter level proportional valve is connected, and realizes that power-up forms high-tension electricity on post through the electric isolution groove .
2. the automatic sampler according to claim 1 for quantitative capillary tube electrophoresis apparatus, it is characterised in that:Described electricity Isolation channel is supported on electric isolution groove support, and the electric isolution groove support is fixed on the upper lid of the automatic sampler.
3. the automatic sampler according to claim 1 for quantitative capillary tube electrophoresis apparatus, it is characterised in that:Described three Individual washer bottle is respectively provided with the HCl or NaOH solution of suitable concentration.
4. the automatic sampler according to claim 1 for quantitative capillary tube electrophoresis apparatus, it is characterised in that:It is described from Dynamic injector realizes the function of nanoliter level quantitative sample injection and activation/cleaning separation capillary column by automated software control.
CN201621332670.4U 2016-12-07 2016-12-07 A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus Active CN206362811U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201621332670.4U CN206362811U (en) 2016-12-07 2016-12-07 A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621332670.4U CN206362811U (en) 2016-12-07 2016-12-07 A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus

Publications (1)

Publication Number Publication Date
CN206362811U true CN206362811U (en) 2017-07-28

Family

ID=59373572

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201621332670.4U Active CN206362811U (en) 2016-12-07 2016-12-07 A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus

Country Status (1)

Country Link
CN (1) CN206362811U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108760420A (en) * 2018-05-08 2018-11-06 湖北工业大学 A kind of sample pre-treatments platform with ultrasonic extraction function
CN109115579A (en) * 2018-10-16 2019-01-01 湖北工业大学 A kind of high throughput sample pre-treatments platform and liquid feeding method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108760420A (en) * 2018-05-08 2018-11-06 湖北工业大学 A kind of sample pre-treatments platform with ultrasonic extraction function
CN109115579A (en) * 2018-10-16 2019-01-01 湖北工业大学 A kind of high throughput sample pre-treatments platform and liquid feeding method

Similar Documents

Publication Publication Date Title
US9903835B2 (en) Fully automated high-precision capillary electrophoresis instrument
CN204116276U (en) The liquid conveying system of full-automatic capillary electrophoresis apparatus
CN102901835B (en) Method and device for collecting sample by full-automatic blood cell analyzer
CN102269732B (en) High speed electrolyte analysis apparatus
CN101750450B (en) Automatic sampling device for array capillary electrophoresis
CN107561198A (en) A kind of liquid chromatograph automatic sampler
CN102353724B (en) On-line detection system and method of trace dissolved gas in organic oil
CN102649121B (en) Sampling needle cleaner and sample analyzing device therewith inside
CN106841483B (en) A kind of sample introduction separator of ping-pong structure
CN108865658B (en) Tubular plasma free nucleic acid extraction method and system
CN206362811U (en) A kind of automatic sampler for quantitative capillary tube electrophoresis apparatus
CN102680545A (en) Test instrument for detecting electrolyte item and total carbon dioxide
CN104792769A (en) Dynamic micro-extraction and detection integrated device and method for compounds in aqueous solution sample
CN109959549A (en) Sample testing method and sample analyser
CN105547937A (en) Automatic control device for detecting erythrocyte sedimentation rate data
CN205786430U (en) A kind of Automatic continuous measures the device of solution ph
CN206177912U (en) Go up appearance device in low -voltage tube
CN103521480B (en) A kind of cleaning method of the automatic clearing apparatus of sampling needle
CN102375073B (en) Fully automatic fluorine analyzer and analytical method thereof
CN109294890A (en) A kind of microbial fermentation multicomponent on-line analysis device and application method
CN106345541A (en) Diphasic liquid-liquid extraction and electrophoretic separation integration microfluidic device and method
CN108845056A (en) A kind of on-line automatic pretreating device of aflatoxin based on flow path switching
CN103543180B (en) For immune impedance biosensor detection method and the pick-up unit of rapid detection for pesticide residue
CN202621512U (en) Sampling needle cleaner and sample analysis device with built-in sampling needle cleaner
CN203786079U (en) Full-automatic high-precision capillary tube electrophoresis apparatus

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant