CN206177912U - Go up appearance device in low -voltage tube - Google Patents
Go up appearance device in low -voltage tube Download PDFInfo
- Publication number
- CN206177912U CN206177912U CN201621176616.5U CN201621176616U CN206177912U CN 206177912 U CN206177912 U CN 206177912U CN 201621176616 U CN201621176616 U CN 201621176616U CN 206177912 U CN206177912 U CN 206177912U
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- way valve
- sample introduction
- working hole
- operating position
- seat
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Abstract
The utility model provides a go up appearance device in low -voltage tube has the six -way valve, connect respectively on six working holes of six -way valve: transfer pump, syringe, flow direction switching valve, advance appearance seat, advance an appearance seat overflow mouth and a gel permeation chromatography post, syringe pump and cleaning solvent interface are still connected to the flow direction switching valve, wherein, the six -way valve has an operating position and the 2nd operating position, at an operating position: the working hole that flow direction switching valve and syringe correspond on through the six -way valve communicates with each other, advances appearance seat overflow mouth and communicates with each other through the working hole that corresponds on the six -way valve with advancing appearance, and the working hole that transfer pump and gel permeation chromatography post correspond on through the six -way valve communicates with each other, at the 2nd operating position: the working hole that transfer pump and syringe correspond on through the six -way valve communicates with each other, advances the working hole that appearance seat and gel permeation chromatography post correspond on through the six -way valve and communicates with each other, advances the working hole that a kind overflow mouth and flow direction switching valve correspond on through the six -way valve and communicates with each other.
Description
Technical field
The utility model device is related to a kind of experiment of biochemistry, automated analysis instrument and liquid to automatically process and set
It is standby, more particularly to a kind of full automatic gel cleaning system.
Background technology
Full automatic gel cleaning system is a kind of gel permeation chromatography device being mainly used in chemical laboratory, is complete
Automatic working method.The system according to gel permeation chromatography principle to complex sample according to the size of molecular volume carry out separate and
Fractional Collections, can effectively remove the macromolecular matrices in sample, and small molecule interfering material, improve the sensitivity of subsequent analysis with
Accuracy, extends the service life of analytical instrument.It is widely used in environment measuring, detection of agricultural products, food inspection and life
The fields such as life science.
The sample size of conventional quantitative loop sample introduction is 1.5-2.5 times of quantitative loop volume, there is larger sample waste.Entirely
The complete loading of automatic gel purification system is difficult in traditional sense, generally requires to exceed well over the sample of loading volume,
Not only making follow-up counter the pushing to of analyze data becomes cumbersome, there is also larger sample waste, especially for expensive sample
Experimentation cost can substantially be increased.Make full automatic gel cleaning system use cost high with this and subsequently calculate cumbersome.
In view of this, in order to solve the above technical problems, I is based on the research and development of association area, and by constantly testing and changing
It is good, and then have generation of the present utility model.
Utility model content
The utility model reaches good using effect and economic benefit, there is provided a kind of low pressure to solve the above problems
Interior sampling device is managed, it is switched using six-way valve as stream, and be aided with the sample introduction seat with sealing structure and constitute the sampling device
Core, by syringe pump draw, automatic sampler move sample introduction needle complete sample introduction process, realize sampling device in the low-voltage tube
Low pressure free of losses loading.
To achieve the above object, the technical solution adopted in the utility model is：
Sampling device in a kind of low-voltage tube, it is characterised in that：With six-way valve, divide on six working holes of the six-way valve
Do not connect：Infusion pump, sample introduction needle, flow to switching valve, sample introduction seat, sample introduction seat overfall and gel permeation chromatographic column；The stream
Syringe pump and cleaning solvent interface are also connected with to switching valve；
Wherein, the six-way valve has the first operating position and the second operating position；
In the first operating position：Flow to switching valve to be communicated by corresponding working hole on six-way valve with sample introduction needle, sample introduction seat
Overfall is communicated with sample introduction seat by corresponding working hole on six-way valve, and infusion pump is with gel permeation chromatographic column by six-way valve
Corresponding working hole is communicated；
In the second operating position：Infusion pump is communicated with sample introduction needle by corresponding working hole on six-way valve, sample introduction seat with it is solidifying
Glue penetration chromatographic column is communicated by corresponding working hole on six-way valve, and sample introduction seat overfall passes through on six-way valve with switching valve is flowed to
Corresponding working hole is communicated.
The utility model has the advantage that compared with prior art：
1st, sample is saved in the utility model application, and the sample for sucking sample introduction needle is entirely used for loading, and n.s are wasted.
2nd, it is clean state n.s residual after the completion of the sample introduction of the utility model application sample introduction needle inside, it is to avoid intersect dirty
Dye.
3rd, saved because being clean state after the completion of sample introduction without cleaning again inside the utility model application sample introduction needle
Cleaning solvent saves operating cost.
Sampling device keeps low-pressure state, the effectively service life of extension sampling device sealing structure when the 4th, running.
Brief description of the drawings
Fig. 1 is overall structure diagram of the present utility model.
Description of reference numerals：1- six-way valves；2- infusion pumps；3- sample introduction needles；4- syringe pumps；5- sample introductions seat overfall；6- enters
Sample seat；7- gel permeation chromatographic columns；8- cleaning solvent interfaces；9- flows to switching valve.
Specific embodiment
The utility model is further described below in conjunction with brief description of the drawings.
As shown in figure 1, the utility model provides sampling device in a kind of low-voltage tube, with six-way valve 1, the six-way valve 1
Six working holes on connect respectively：Infusion pump 2, sample introduction needle 3, flow to switching valve 9, sample introduction seat 6, sample introduction seat overfall 5 and
Gel permeation chromatographic column 7；The switching valve 9 that flows to is also connected with syringe pump 4 and cleaning solvent interface 8.
It is as follows using process：
1) to avoid air from entering system, first automatic sampler is filled the pipeline of sample introduction seat 6 to six-way valve 1 before sample introduction
It is full.In this step, the six-way valve 1 is in the first operating position, i.e.,：Switching valve 9 is flowed to sample introduction needle 3 by six-way valve 1
Corresponding working hole is communicated；Sample introduction seat overfall 5 is communicated with sample introduction seat 6 by corresponding working hole on six-way valve 1；Infusion pump 2
Communicated by corresponding working hole on six-way valve 1 with gel permeation chromatographic column 7.Also, sample introduction needle 3 be moved to loading position and with
6 UNICOMs of sample introduction seat.After being ready to, syringe pump 4 is connected by flowing to switching valve 9 with cleaning solvent interface 8, molten to draw cleaning
Agent, then, changing flow direction switching valve 9 makes syringe pump 4 be communicated with six-way valve 1, and the cleaning solvent that syringe pump 4 will be drawn is through flow direction
Switching valve 9 push back six-way valve 1 again by sample introduction needle 3 be delivered to sample introduction seat 6, and into sample introduction seat 6 cleaning solvent lead to again
Six-way valve 1 is crossed to be flowed out from sample introduction seat overfall 5.
2) sample introduction needle 3 is moved to sample position by automatic sampler, and the six-way valve 1 is still within the first operating position,
Syringe pump 4 is communicated by flowing to switching valve 9 with six-way valve 1.
3) syringe pump 4 draws loading volume, sucks the sample into sample introduction needle 3.
4) automatic sampler by sample introduction needle 3 be moved to loading position and with sample introduction seat 6 UNICOMs.Now sample is stored in completely
In sample introduction needle 3.
5) switch six-way valve, the six-way valve 1 is in the second operating position, i.e.,：Infusion pump 2 passes through six with sample introduction needle 3
Corresponding working hole is communicated in port valve 1；Sample introduction seat 6 is with gel permeation chromatographic column 7 by corresponding working hole phase on six-way valve 1
It is logical；Sample introduction seat overfall 5 is communicated with switching valve 9 is flowed to by corresponding working hole on six-way valve 1.Due to the now He of sample introduction needle 3
Sample introduction seat 6 is in UNICOM's state, and after infusion pump 2 works, system fluid flows out from the place working hole of sample introduction needle 3, by sample introduction needle 3
Sample bring into system fluid in the lump, then 6 flow back to six-way valve 1 through sample introduction seat, the finally work from where gel permeation chromatographic column 7
Mouth outflow.The sample sucked in sample introduction needle 3 during whole loading is brought into gel permeation chromatographic column 7 completely.
6) after sample is completely into gel permeation chromatographic column 7, the operating position of six-way valve 1 to the first is switched.Mobile phase is by defeated
Liquid pump 2 flows to gel permeation chromatographic column 7 and completes separation process of the subsequent sample in gel permeation chromatographic column 7 through six-way valve 1.
The traditional sample loading mode of the utility model contrast is in step 3) in avoid sample waste.Traditional sample loading mode is similar
Step 3) during can draw a part of samples more and be used to fill quantitative loop end pipeline, the sample segment when stream is switched
System can not be entered, cause loading volume less than the situation of volume aspirated, not only wasting sample can also cause cross pollution.This
Sampling device not only solves the problems, such as that sample waste also avoid cross pollution well in low-voltage tube.
It is above illustrative and not restrictive to description of the present utility model, those skilled in the art understands, in power
Profit requires that it can be carried out many modifications, change or equivalent within the spirit and scope for limiting, but they fall within this reality
With in new protection domain.
Claims (1)
1. sampling device in a kind of low-voltage tube, it is characterised in that：With six-way valve, on six working holes of the six-way valve respectively
Connection：Infusion pump, sample introduction needle, flow to switching valve, sample introduction seat, sample introduction seat overfall and gel permeation chromatographic column；The flow direction
Switching valve is also connected with syringe pump and cleaning solvent interface；
Wherein, the six-way valve has the first operating position and the second operating position；
In the first operating position：Flow to switching valve to be communicated by corresponding working hole on six-way valve with sample introduction needle, sample introduction seat overflow
Mouth is communicated with sample introduction seat by corresponding working hole on six-way valve, and infusion pump is with gel permeation chromatographic column by corresponding on six-way valve
Working hole communicate；
In the second operating position：Infusion pump is communicated with sample introduction needle by corresponding working hole on six-way valve, and sample introduction seat oozes with gel
Saturating chromatographic column is communicated by corresponding working hole on six-way valve, and sample introduction seat overfall passes through corresponding on six-way valve with switching valve is flowed to
Working hole communicate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621176616.5U CN206177912U (en) | 2016-11-02 | 2016-11-02 | Go up appearance device in low -voltage tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621176616.5U CN206177912U (en) | 2016-11-02 | 2016-11-02 | Go up appearance device in low -voltage tube |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206177912U true CN206177912U (en) | 2017-05-17 |
Family
ID=58682758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621176616.5U Active CN206177912U (en) | 2016-11-02 | 2016-11-02 | Go up appearance device in low -voltage tube |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206177912U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107561198A (en) * | 2017-08-24 | 2018-01-09 | 通用（深圳）仪器有限公司 | A kind of liquid chromatograph automatic sampler |
| CN112362794A (en) * | 2020-11-10 | 2021-02-12 | 山东悟空仪器有限公司 | Sample feeder, full-loop sample feeding method, liquid analysis method and liquid chromatography system |
| CN114923993A (en) * | 2022-04-15 | 2022-08-19 | 华南理工大学 | Liquid chromatography system based on pre-column online derivation method and use method |
-
2016
- 2016-11-02 CN CN201621176616.5U patent/CN206177912U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107561198A (en) * | 2017-08-24 | 2018-01-09 | 通用（深圳）仪器有限公司 | A kind of liquid chromatograph automatic sampler |
| CN112362794A (en) * | 2020-11-10 | 2021-02-12 | 山东悟空仪器有限公司 | Sample feeder, full-loop sample feeding method, liquid analysis method and liquid chromatography system |
| CN114923993A (en) * | 2022-04-15 | 2022-08-19 | 华南理工大学 | Liquid chromatography system based on pre-column online derivation method and use method |
| CN114923993B (en) * | 2022-04-15 | 2023-06-20 | 华南理工大学 | Liquid chromatography system based on pre-column online derivatization method and application method |
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