CN205420418U - External cell compressive stress loading device - Google Patents
External cell compressive stress loading device Download PDFInfo
- Publication number
- CN205420418U CN205420418U CN201620271483.3U CN201620271483U CN205420418U CN 205420418 U CN205420418 U CN 205420418U CN 201620271483 U CN201620271483 U CN 201620271483U CN 205420418 U CN205420418 U CN 205420418U
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- cell
- cell culture
- compressive stress
- data acquisition
- air
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Abstract
The utility model discloses an external cell compressive stress loading device, including data acquisition module, cell culture module, electronic module gentleness moulding -die piece, data acquisition module includes data collection station, drive circuit and gain amplifier, gain amplifier is connected with data collection station, the cell culture module includes air outlet solenoid valve, cell culture chamber and pressure sensor, air outlet solenoid valve is connected with the cell culture chamber, electronic module includes cylinder, linear stepping motor and power amplifier, the cylinder is connected with linear stepping motor, the atmospheric pressure module includes steel bottle, air solenoid valve, air cleaner and relief pressure valve, the steel bottle is connected with air solenoid valve, air solenoid valve is connected with air cleaner, air cleaner is connected with the relief pressure valve. The utility model discloses stable performance, easy operation can carry out the compressive stress loading to culture cell external under appointed culture conditions.
Description
Technical field
This utility model relates to cell cultivation technical field, is specifically related to a kind of cell in vitro compressive stress charger.
Background technology
nullCyto-mechanics is one of basis of organizational project，It is often required to study mechanics factor to cellular morphology change and the impact of growth，Owing to the structure of bio-tissue and organ is extremely complex，Bigger difference is there is also between bion，Cause in somatic mechanical environment complexity various，Thus increase the difficulty in the research of somatic cell mechanical behavior，In soma、Cell pressurized is a kind of bearing mode that organism is common，In musculoskeletal system，Skeleton is the carrying structure that human body is main，It provides support frame for human body，Protection internal organs，And complete the transmission of power，The human body cartilage of joint part，Often bear the compressive stress load through skeleton transmission，The effect of the compressive stress growth to articular cartilage、Metabolism etc. are most important，Therefore，Under research compressive stress load, the mechanical behavior tool of cell is of great significance，The basis of cyto-mechanics research and it is crucial that cell loading technique，Owing to the size of human body cell is between ten a few to tens of microns，The thickness of cell membrane only has several nanometer to tens nanometer，Conventional macromechanics loading method and experimental technique cannot directly use.
Utility model content
For problem above, this utility model provides a kind of cell in vitro compressive stress charger, stable performance, simple to operate, compressive stress loading can be carried out under the condition of culture specified to cultivating cell in vitro, the parameters such as pressure size, frequency, persistent period can be regulated and controled.
nullTo achieve these goals，The technical solution adopted in the utility model is as follows: a kind of cell in vitro compressive stress charger，Including data acquisition module、Media to cell culture modules、The gentle die block of electric module，Described data acquisition module includes data acquisition unit、Drive circuit and gain amplifier，Described gain amplifier is connected with data acquisition unit，Described data acquisition unit is connected with drive circuit，Described media to cell culture modules includes electromagnetic valve of giving vent to anger、Cell culture chamber and pressure transducer，Described electromagnetic valve of giving vent to anger is connected with cell culture chamber，Described cell culture chamber is connected with pressure transducer，Described electric module includes cylinder、Linear stepping motor and power amplifier，Described cylinder is connected with linear stepping motor，Described linear stepping motor is connected with power amplifier，Described air pressure module includes steel cylinder、Air inlet electromagnetic valve、Air filter and air relief valve，Described steel cylinder is connected with air inlet electromagnetic valve，Described air inlet electromagnetic valve is connected with air filter，Described air filter is connected with air relief valve.
Further, described air inlet electromagnetic valve is connected with drive circuit.
Further, electromagnetic valve of giving vent to anger described in is connected with drive circuit.
Further, described air relief valve is connected with cell culture chamber.
Further, described cylinder is connected with cell culture chamber.
Further, described power amplifier is connected with data acquisition unit.
Further, described pressure transducer is connected with gain amplifier.
The beneficial effects of the utility model: this utility model stable performance, simple to operate, culture and the bonding state in base, cell uniform force are easily transmitted and do not relied on to load, in vitro cultivation cell can be carried out compressive stress loading under the condition of culture specified, the parameters such as pressure size, frequency, persistent period can be regulated and controled, use pressure transducer, can detect the size of force value exactly, accurately and reliably, pressing time is adjustable in the effect of pressure.
Accompanying drawing explanation
Fig. 1 is this utility model overall structure schematic diagram.
Figure is numbered: 1-data acquisition module, 2-media to cell culture modules, 3-electric module, 4-air pressure module, 5-data acquisition unit, 6-drive circuit, 7-gain amplifier, 8-gives vent to anger electromagnetic valve, 9-cell culture chamber, 10-pressure transducer, 11-cylinder, 12-linear stepping motor, 13-power amplifier, 14-steel cylinder, 15-air inlet electromagnetic valve, 16-air filter, 17-air relief valve.
Detailed description of the invention
In order to make the purpose of this utility model, technical scheme and advantage clearer, below in conjunction with drawings and Examples, this utility model is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain this utility model, is not used to limit this utility model.
nullAs shown in Figure 1，A kind of cell in vitro compressive stress charger，Including data acquisition module 1、Media to cell culture modules 2、The gentle die block of electric module 34，Described data acquisition module 1 includes data acquisition unit 5、Drive circuit 6 and gain amplifier 7，Described gain amplifier 7 is connected with data acquisition unit 5，Described data acquisition unit 5 is connected with drive circuit 6，Described media to cell culture modules 2 includes electromagnetic valve 8 of giving vent to anger、Cell culture chamber 9 and pressure transducer 10，Described electromagnetic valve 8 of giving vent to anger is connected with cell culture chamber 9，Described cell culture chamber 9 is connected with pressure transducer 10，Described electric module 3 includes cylinder 11、Linear stepping motor 12 and power amplifier 13，Described cylinder 11 is connected with linear stepping motor 12，Described linear stepping motor 12 is connected with power amplifier 13，Described air pressure module 4 includes steel cylinder 14、Air inlet electromagnetic valve 15、Air filter 16 and air relief valve 17，Described steel cylinder 14 is connected with air inlet electromagnetic valve 15，Described air inlet electromagnetic valve 15 is connected with air filter 16，Described air filter 16 is connected with air relief valve 17.
On above-described embodiment preferably, described air inlet electromagnetic valve 15 is connected with drive circuit 6.
On above-described embodiment preferably, electromagnetic valve 8 of giving vent to anger described in is connected with drive circuit 6.
On above-described embodiment preferably, described air relief valve 17 is connected with cell culture chamber 9.
On above-described embodiment preferably, described cylinder 11 is connected with cell culture chamber 9.
On above-described embodiment preferably, described power amplifier 13 is connected with data acquisition unit 5.
On above-described embodiment preferably, described pressure transducer 10 is connected with gain amplifier 7.
Based on above-mentioned, this utility model stable performance, simple to operate, culture and the bonding state in base, cell uniform force are easily transmitted and do not relied on to load, in vitro cultivation cell can be carried out compressive stress loading under the condition of culture specified, the parameters such as pressure size, frequency, persistent period can be regulated and controled, use pressure transducer, it is possible to detect the size of force value exactly, accurately and reliably, pressing time is adjustable in the effect of pressure.
The foregoing is only preferred embodiment of the present utility model, not in order to limit this utility model, all any amendment, equivalent and improvement etc. made within spirit of the present utility model and principle, within should be included in protection domain of the present utility model.
Claims (7)
- null1. a cell in vitro compressive stress charger，It is characterized in that: include data acquisition module、Media to cell culture modules、The gentle die block of electric module，Described data acquisition module includes data acquisition unit、Drive circuit and gain amplifier，Described gain amplifier is connected with data acquisition unit，Described data acquisition unit is connected with drive circuit，Described media to cell culture modules includes electromagnetic valve of giving vent to anger、Cell culture chamber and pressure transducer，Described electromagnetic valve of giving vent to anger is connected with cell culture chamber，Described cell culture chamber is connected with pressure transducer，Described electric module includes cylinder、Linear stepping motor and power amplifier，Described cylinder is connected with linear stepping motor，Described linear stepping motor is connected with power amplifier，Described air pressure module includes steel cylinder、Air inlet electromagnetic valve、Air filter and air relief valve，Described steel cylinder is connected with air inlet electromagnetic valve，Described air inlet electromagnetic valve is connected with air filter，Described air filter is connected with air relief valve.
- A kind of cell in vitro compressive stress charger the most according to claim 1, it is characterised in that: described air inlet electromagnetic valve is connected with drive circuit.
- A kind of cell in vitro compressive stress charger the most according to claim 1, it is characterised in that electromagnetic valve of giving vent to anger described in: is connected with drive circuit.
- A kind of cell in vitro compressive stress charger the most according to claim 1, it is characterised in that: described air relief valve is connected with cell culture chamber.
- A kind of cell in vitro compressive stress charger the most according to claim 1, it is characterised in that: described cylinder is connected with cell culture chamber.
- A kind of cell in vitro compressive stress charger the most according to claim 1, it is characterised in that: described power amplifier is connected with data acquisition unit.
- A kind of cell in vitro compressive stress charger the most according to claim 1, it is characterised in that: described pressure transducer is connected with gain amplifier.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620271483.3U CN205420418U (en) | 2016-03-31 | 2016-03-31 | External cell compressive stress loading device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620271483.3U CN205420418U (en) | 2016-03-31 | 2016-03-31 | External cell compressive stress loading device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205420418U true CN205420418U (en) | 2016-08-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620271483.3U Expired - Fee Related CN205420418U (en) | 2016-03-31 | 2016-03-31 | External cell compressive stress loading device |
Country Status (1)
| Country | Link |
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| CN (1) | CN205420418U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113444642A (en) * | 2021-07-29 | 2021-09-28 | 中国科学院长春光学精密机械与物理研究所 | Pneumatic system for cell loading and control method |
-
2016
- 2016-03-31 CN CN201620271483.3U patent/CN205420418U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113444642A (en) * | 2021-07-29 | 2021-09-28 | 中国科学院长春光学精密机械与物理研究所 | Pneumatic system for cell loading and control method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Gang Inventor after: Meng Songdong Inventor before: Zhao Wenxu |
|
| COR | Change of bibliographic data | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170125 Address after: Haicang District of Xiamen City, Fujian province 361000 Weng Kok Road No. 2050 Xiamen Biomedical Industry Park 1 Building 8 floors Patentee after: And Wang (Xiamen) Biological Technology Co. Ltd. Address before: 311805 Zhejiang city of Shaoxing province Zhuji City Jie Ting Zhen Peng Cun head No. 33 pagoda tree Patentee before: Zhao Wenxu |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160803 Termination date: 20180331 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |