CN204233506U - A kind of test kit of rapid extraction blood plasma - Google Patents
A kind of test kit of rapid extraction blood plasma Download PDFInfo
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- CN204233506U CN204233506U CN201420700817.5U CN201420700817U CN204233506U CN 204233506 U CN204233506 U CN 204233506U CN 201420700817 U CN201420700817 U CN 201420700817U CN 204233506 U CN204233506 U CN 204233506U
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Abstract
The utility model discloses a kind of test kit of rapid extraction blood plasma, comprise: box body (1), the lid (2) hinged with described box body (1), some mutually isolated memory blocks are disposed with in described box body (1), the injection device (3) having centrifuge tube and syringe function concurrently is placed with respectively in described memory block, conventional syringe (4), joint (5) between syringe, rubber flexible pipe (6), ethanol cotton piece (7), injection normal saline (8), be loaded with blood anticoagulant respectively, the reagent bottle (9) of platelet anticoagulant and platelet activating agent and blood taking needle and silica gel hose (10) of infusing, this test kit can facilitate, efficiently, fast, safely, sterilely extract poor and platelet rich plasma simultaneously, test kit is supplied to user comprehensively, when being separated thrombocyte plasma, nearly all material required except centrifuge, is convenient to the use of basic hospital or beauty treatment mechanism very much.
Description
Technical field
This utility model relates to test kit field, specifically provides a kind of test kit of rapid extraction blood plasma, can realize extracting platelet rich plasma and platelet poor plasma simultaneously.
Background technology
Platelet rich plasma (platelet-rich plasma, PRP) be fresh anticoagulated whole blood after certain condition is centrifugal, the blood plasma that separation and Extraction is higher than platelet content in normal whole blood 4 ~ 6 times.
The PRP extracted in human plasma, containing more than 400 kinds of somatomedin, as: platelet derived growth factor (platelet-derived growthfactor, PDGF), transforming growth factor-β (transforming growth factor, TGF-β), VEGF (vascularendothelial growth factor, VEGF), epidermal growth factor (vascularendothelial growthfactor, EGF), para-insulin like growth factor (insulin-like growthfactor, IGF), fibroblast growth factor (fibroblast growth factor, FGF) etc.The somatomedin in these platelet source, can attract macrophage, mescenchymal stem cell and osteoblast etc., and play an important role to the Differentiation and proliferation of cell, have obvious facilitation to wound healing, reparation and regeneration.Therefore be effectively separated and improve hematoblastic concentration in PRP and become the key of whole PRP therapeutic scheme.
The preparation of current PRP is praised highly and is extracted from patient's self-blood, because this has many good qualities: as abundance, draw materials conveniently and preparation method is simple, body absorption fast, self PRP it also avoid virus disseminating and immunologic rejection problem simultaneously, fool proof, therefore PRP is widely applied in different medical domains, as orthopaedics, the department of stomatology, decorative sursery, sports medical science and aesthetic medicine etc.
In blood, separation energy is extracted outside PRP, also has the platelet poor plasma (Platelet Poor Plasma, PPP) of upper strata more, though PPP does not have, PRP's is powerful, and recent research confirms, PPP is also a rare resource, cosmetically autologous, PPP has unique effect.PPP is in heating or after adding the reagent such as calcium and thrombin Gu Yuan process, can be made into the protein filled thing of autologous collagen, adopt tiny needle set to be injected at subcutaneous layer of fat, cosmetically can have following subject range: fill all kinds of wrinkle, sculpture type body, fill recessed scar, solve two chivalrous depression, modify chin profile, rich buccal, to fill below eye depression and improve other tissue site profiles etc." hyaluronic acid " that the autologous collagen albumen be made up of PPP is conventional compared with beauty parlor and " collagen protein " injectant, client Geng Yi accepts, because this is from autologous, be not external medicine (foreign body), almost without swelling after injection, anaphylaxis, can take effect at once.
Developing rapidly of this field, occurred apparatus and the method for a lot of preparation PRP, its ultimate principle mainly utilizes the difference in blood on various composition proportion, and the sedimentation velocity caused is different thereupon, by centrifugal by blood layering, these methods can be divided into again manual method (centrifuging and secondary centrifuging method) and instrument preparation method, as gathered the machine of PRP, as the HARVEST I of the U.S., II etc., but their prevailing prices are expensive, need special consumptive material, limited during use.Secondary centrifuging method also exists that complicated operation, process are very long, the risk of contamination of products, and platelet in PRP is more fragile in vitro and easily activate, too high centrifugal speed and the centrifugal number of times of increase, capital make platelet membrane break reduce its biological activity, cause hematoblastic loss, and then in individuation clinical practice and be cosmetically restricted.
At present, the PRP preparation system commercially produced both at home and abroad and the test kit of exploitation, its main shortcoming be price costly, and need supporting centrifuge instrument, be unfavorable for applying of PRP technology clinical and beauty parlor in China.
therefore, research and develop a kind of facility complete, cheap, test kit easy to use, becomes people's problem demanding prompt solution.
Utility model content
Given this, the purpose of this utility model is the test kit providing a kind of rapid extraction blood plasma, incomplete with the facility at least solving test kit existence in the past, complicated operation, expensive, the function that PPP and PRP extracts simultaneously cannot be carried out, and be unfavorable for the problem such as apply of PRP technology in clinical and beauty parlor of China.
The scheme that this utility model provides, be specially, a kind of test kit of rapid extraction blood plasma, it is characterized in that, comprise: box body 1, the lid 2 hinged with described box body 1, some mutually isolated memory blocks are disposed with in described box body 1, the injection device 3 having centrifuge tube and syringe function concurrently is placed with respectively in described memory block, conventional syringe 4, joint 5 between syringe, rubber flexible pipe 6, ethanol cotton piece 7, injection normal saline 8, be loaded with blood anticoagulant respectively, the reagent bottle 9 of platelet anticoagulant and platelet activating agent and blood taking needle and transfusion silica gel hose 10,
Wherein, described injection device 3 comprises,
Injection tube 31, its entirety is cylindrical, and inside is provided with and holds cavity 311, and is provided with the tip 312 be communicated with described accommodation cavity 311 in the upper end of described injection tube 31;
Propulsion plant 32, it is movably set in described accommodation cavity 311 in the mode that can vertically move, and described propulsion plant 32 comprises piston head 321 and pushing ram 322, and described pushing ram 322 is flexibly connected with the lower end of described piston head 321, can carry out free dismounting.
Preferably, described piston head 321 comprises: soft rubber head 3211 and being positioned at below described soft rubber head 3211, and the hard connecting portion 3212 be fixedly connected with described soft rubber head 3211, described soft rubber head 3211 is at least provided with 3 circle sealing rings.
Further preferably, be also placed with cap head 11 in described memory block, tip 312 outer cover of described injection tube 31 is equipped with connecting cylinder 313, and the lower end of described connecting cylinder 313 is fixedly connected with described injection tube 31; The size of described cap head 11 is mated with the size of described connecting cylinder 313.
Further preferably, back cover lid 12 is also placed with in described memory block, the front cover 122 that described back cover lid 12 comprises closure part 121 and is fixedly connected with lower end, described closure part 121; Described closure part 121 is cylinder, and the diameter of its diameter and described accommodation cavity 311 matches; Described front cover 122 is circular, and its diameter is greater than/equals the external diameter of described injection tube 31.
Further preferably, in described back cover lid 12, closure part 121 is hollow cylinder, and the top 1211 of described closure part 121 progressively reduces along its axial bore from the bottom to top, and top 12111 caliber size of described closure part 121 is mated with hard connecting portion 3212 size in described piston head 321.
Further preferably, in described back cover lid 12, the height of closure part 121 equals/is greater than the height of hard connecting portion 3212 in described piston head 321.
Further preferably, be also placed with pedestal 13 in described memory block, described pedestal 13 is provided with groove 131, the size of described groove 131 and the bottom size of described pushing ram 322 match.
Further preferably, tee T 14 is also placed with in described memory block.
Further preferably, the number of described conventional syringe 4 is 3, wherein, has the volume of 2 conventional syringe 4 identical, is all less than the volume of another conventional syringe 4.
The test kit of the rapid extraction blood plasma that this utility model provides, the multiple equipment of splendid attire, its very well equipped, and possess the injection device having centrifuge tube and syringe function concurrently, simple to operate, go for the centrifuge of various model, and the extraction and isolation of PPP and PRP can be realized simultaneously, with low cost.
Agent box in this utility model can facilitate, efficiently, fast, safely, sterilely extract poor and platelet rich plasma simultaneously, when test kit is supplied to user separation thrombocyte plasma comprehensively, nearly all material required except centrifuge, is convenient to the use of basic hospital or beauty treatment mechanism very much.
Accompanying drawing explanation
Fig. 1 is the reagent cartridge configuration schematic diagram of rapid extraction blood plasma;
Fig. 2 is the structural representation of box body;
Fig. 3 is the structural representation of injection device a state;
Fig. 4 is the structural representation of propulsion plant;
Fig. 5 is the structural representation of cap head;
Fig. 6 is the structural representation of back cover lid;
Fig. 7 is the structural representation of injection device b state;
Fig. 8 is the structural representation of pedestal.
Detailed description of the invention
Further illustrate content of the present invention with specific embodiment below, but should not be construed as limitation of the present invention.Without departing from the spirit and substance of the case in the present invention, the amendment do the inventive method, step or condition or replacement, all belong to scope of the present invention.
See the test kit that Fig. 1 is a kind of rapid extraction blood plasma, it is made up of box body 1 and the lid 2 hinged with box body 1, wherein, see Fig. 2, be disposed with some mutually isolated memory blocks in box body 1, be placed with respectively in described memory block have centrifuge tube and syringe function concurrently injection device 3, conventional syringe 4, joint 5, rubber flexible pipe 6, ethanol cotton piece 7, injection normal saline 8, the reagent bottle 9 being loaded with blood anticoagulant, platelet anticoagulant and platelet activating agent respectively and blood taking needle and transfusion silica gel hose 10 between syringe;
Wherein, see Fig. 3, injection device 3 comprises,
Injection tube 31, in order to realize the function of its centrifuge tube, the size of injection tube is conveniently enable to match with numerous centrifuge, simultaneously also in order to improve centrifugal degree of stability when carrying out centrifugal blood, the outer rim extended laterally conventional injection cylinder lower end is removed, make the entirety of injection tube cylindrical, inside is provided with and holds cavity 311, and the tip 312 be communicated with described accommodation cavity 311 is provided with in the upper end of described injection tube 31, this tip can be used for syringe needle or various connection tube connects, realize extraction or the separation function of injection tube, wherein, the optional 2ml of injection tube, 5ml, 20ml, 30ml and 50ml all size, meet the demand of different situations, facilitate clinical practice, easily especially to promote the use of at middle and small hospital and beauty parlor, propulsion plant 32, it is movably set in described accommodation cavity 311 in the mode that can vertically move, described propulsion plant 32 comprises piston head 321 and pushing ram 322, and described pushing ram 322 is flexibly connected with the lower end of described piston head 321, free dismounting can be carried out, wherein, the movable connection method of piston head and pushing ram can be selected multiple, as being threaded, buckle connection, push button connection etc.
The specific works process of this injection device is: 1, blood draw, the tip of injection tube is connected with intravenous transfusion device connection tube, and the other end of intravenous transfusion device connection tube is connected with intravenous infusion apparatus needle, or the tip of intravenous infusion apparatus needle direct injection cylinder is connected, pass propulsion plant backward, realize blood draw, realize the function of its syringe.2, centrifugal blood, after blood draw terminates, continues to pass propulsion plant backward, until piston head is moved to appropriate location, pushing ram and piston head are dismantled, after taking out pushing ram, injection tube is put into centrifuge and carries out centrifugal blood, make blood layering, then carry out follow-up mask work.
Wherein, blood taking needle is ordinary matches syringe pin, or the syringe needle that can match with transfusion silica gel hose, can join one or more.
Described transfusion silica gel hose is Dispoable medical sebific duct, can be connected, can be several with syringe needle and syringe.
Described blood anticoagulant is the anticoagulant commonly used clinically, as: ACD (Acid Citrate Dextrose-Solution A: ACD-A), ethylenediaminetetraacetic acid (Ethylene DiamineTetraacetic Acid: EDTA), disodiumedetate, calcio-disodium edetate, heparin or hirudin etc., usually store by airtight sterile vials or ampulla, standing 5 milliliters one bottle (the large I of volume determines according to practical situation, between 1-10 milliliter).
Described platelet anticoagulant, with PGE1, stores by airtight sterile vials or ampulla, standing 1 milliliter one bottle (the large I of volume determines according to practical situation, between 0.5-3 milliliter).
Described platelet activating agent, is made up of 10% calcium chloride and 90% thrombin, namely contains 10g calcium chloride in 100mL solution, 90g thrombin, standing 2 milliliters one bottle.
Described injection normal saline, is 0.9% aseptic sodium chloride solution that hospital is conventional, stores, can be used for the dilution to reagent, standing 10 milliliters one bottle by airtight sterile vials or ampulla.
Described ethanol pad is the skin antiseptic of merchandized handling, and packaging is easy to use separately, as: the textile alcohol disinfecting cotton piece of PurCotton medical grade, standing 5 to 10.
In order to improve the connection between piston head 321 and pushing ram 322, as improvement, see Fig. 4, described piston head 321 comprises: soft rubber head 3211 and be positioned at below described soft rubber head 3211, and the hard connecting portion 3212 be fixedly connected with described soft rubber head 3211, described soft rubber head 3211 is at least provided with 3 circle sealing rings, wherein, the object of soft rubber head is that it both can realize the shutoff of injection tube, can also move freely in the accommodation cavity of injection tube simultaneously, its sealing ring is mainly for the sealing between piston head and accommodation cavity, prevent to leak outside, and the connection of conveniently pushing ram and its lower end, lower end is designed to hard connecting portion and makes it have impetus, a kind of connected mode is as shown in Figure 4, the below of hard connecting portion is provided with tapped blind hole, the upper end of pushing ram is provided with threaded rod, by coordinating of threaded rod and tapped blind hole, realize being flexibly connected of piston head and pushing ram, because the mode be flexibly connected has multiple, here just do not enumerate.
See Fig. 2, in memory block, be also placed with cap head 11, see Fig. 5, tip 312 outer cover of injection tube 31 is equipped with connecting cylinder 313, and the lower end of described connecting cylinder 313 is fixedly connected with described injection tube 31; The size of described cap head 11 is mated with the size of described connecting cylinder 313; By using cap head by most advanced and sophisticated shutoff, reasonable with the external world, after namely blood drawing terminates, use cap head by most advanced and sophisticated shutoff at once, avoid the pollution of blood, the extraction quality of the blood of raising.And the connected mode of connecting cylinder and cap head, can select to be provided with screw thread on the lateral wall of connecting cylinder, the medial wall of cap head is also provided with screw thread, the two is threaded connection, certainly the two by being respectively arranged with the form of groove/land on sidewall, can also carry out buckle connection, as long as do not drop when ensureing centrifugal, effective preventing pollution.See Fig. 5, be a kind of structure of cap head, its top is hemispherical, and its underpart is coordinate with connecting cylinder cylindrical.
See Fig. 2, in memory block, be also placed with back cover lid 12, see Fig. 6, the front cover 122 that back cover lid 12 comprises closure part 121 and is fixedly connected with lower end, described closure part 121; Described closure part 121 is cylinder, and the diameter of its diameter and described accommodation cavity 311 matches, and holds in cavity for being plugged in; Described front cover 122 is circular, its diameter is greater than/equals the external diameter of described injection tube 31, see Fig. 7, enable back cover lid just be positioned in the bottom of concentrator bowl, can piston head is plugged in bottom injection tube on the one hand, expand centrifugal volume, keep volumetric blood constant, and strengthen piston head, ensured and not leaked outside when centrifugal, prevent the accident of piston to drop, stable when ensureing centrifugal simultaneously; The effect of this back cover lid is, when carrying out centrifugal blood, due to the effect of centrifugal force, piston head can be moved, and leaks, and brings difficulty for centrifugal, therefore by using this back cover lid by the bottom shutoff of injection tube, piston head can be withstood, to improve stability.
As the improvement of technical scheme, in described back cover lid 12, closure part 121 is hollow cylinder, and the top 1211 of described closure part 121 progressively reduces along its axial bore from the bottom to top, and top 12111 caliber size of described closure part 121 is mated with hard connecting portion 3212 size in described piston head 321.
As the further improvement of technical scheme, in described back cover lid 12, the height of closure part 121 equals/is greater than the height of hard connecting portion 3212 in described piston head 321.
Conveniently operate, see Fig. 2, pedestal 13 is also placed with in described memory block, see Fig. 8, described pedestal 13 is provided with groove 131, the size of described groove 131 and the bottom size of described pushing ram 322 match, conveniently the extraction element of blood plasma is inverted, the bottom of pushing ram is fixed on this pedestal, to carry out the subsequent step operation of blood extraction, this pedestal can be made into single circle, also can be made into the bar shaped of putting multiple syringe, available plastics or metal are made, and see Fig. 8 only for a single circle.
In order to further facilitate the separation and Extraction of blood, see Fig. 2, in described memory block, be also placed with tee T 14, for disposable medical aseptic plastic small articles, can be connected with rubber hose for medical or directly with syringe, switch is one-way flow switch, can distribute the single flow direction of blood.
As the further improvement of technical scheme, the number of described conventional syringe 4 is 3, wherein, has the volume of 2 conventional syringe 4 identical, is all less than the volume of another conventional syringe 4.
The extraction element of above blood plasma is that the mode of going forward one by one carries out writing, and highlights the difference of each embodiment, and its similar portion can cross-reference, the not solution of influence technique problem and the generation of technique effect.
The work process of this test kit is:
1) adopt injection device first to extract the ACD anticoagulant of transfusion rank, after ethanol cotton piece sterilization blood sampling site, carry out venous blood collection, 18 milliliters, aseptic collection venous blood, wherein the volume ratio of anticoagulant and whole blood is 1: 9 ~ 10;
2) pull out syringe needle after having taken a blood sample, seal the tip on injection tube with cap head, gentle inversion injection tube for several times, makes whole blood and anticoagulant fully mix repeatedly;
3) propulsion plant of rotary injection device, the position of the movable choice in centre by piston head and pushing ram disconnects, and namely device pushing ram is separated with piston head, then with back cover lid, the bottom end outlet of injection tube is sealed, again that injection tube back cover is downward, be positioned over carry out in centrifuge centrifugal;
4) under room temperature state (15 ~ 25 DEG C), centrifugal speed 1200 ~ 3500rpm, centrifugation time 5 ~ 15min;
5) after centrifugal end, removing back cover lid rotates back to pushing ram in accommodation cavity again, be inverted in again on syringe rack, visible centrifugal rear blood divides three layers, lower floor is erythrocyte (RBC) layer, account for 45%, tunica albuginea layer that middle level is leukocyte (WBC) and platelet (PLE) accounts for 1%, upper strata is that plasma layer accounts for 54%;
6) remove cap head and change connection tube, connection tube is connected with the T-shaped tee T of belt switch, T-shaped tee T connects two syringes not of uniform size more respectively, first open large syringe, pushing syringe piston, in the platelet poor plasma (PPP) on centrifugal rear upper strata is collected in, retain tunica albuginea and the plasma layer of 3 ~ 10 height on red blood cell layer, stir T-shaped tee T switch again, close large syringe passage, open little syringe passage, tunica albuginea and platelet rich plasma (PRP) are collected in little syringe, thus complete being separated platelet poor plasma (PPP) and platelet rich plasma (PRP) simultaneously,
7) after preparing platelet rich plasma (PRP), platelet can activate after excitation light irradiation, also platelet can be activated with aseptic human thrombin 500U/ml and 10% (9mmol/L) calcium chloride activator, in activator and syringe, the volume ratio of PRP is 1: 9 ~ 10, activation act completes between two little syringes, two little syringes are connected with union joint, gently push-and-pull repeatedly, after platelet and activator are fully mixed, thus activate platelet.Various somatomedin will be discharged in Platelet alpha granule after activation, and give play to and repaired damage, attract stem cell, promote the effects such as collagen protein synthesis, treatment or beauty treatment can be directly used in, or it be frozen to be placed in sterile chamber-80 DEG C.
Thus realize the function of this test kit rapid extraction platelet rich plasma and platelet poor plasma.
Detailed description of the invention of the present utility model, is carry out writing according to the mode of going forward one by one, highlights the difference of each embodiment, and its similarity can cross-reference, the not solution of influence technique problem and the generation of technique effect.
Claims (9)
1. the test kit of a rapid extraction blood plasma, it is characterized in that, comprise: box body (1), the lid (2) hinged with described box body (1), some mutually isolated memory blocks are disposed with in described box body (1), the injection device (3) having centrifuge tube and syringe function concurrently is placed with respectively in described memory block, conventional syringe (4), joint (5) between syringe, rubber flexible pipe (6), ethanol cotton piece (7), injection normal saline (8), be loaded with blood anticoagulant respectively, the reagent bottle (9) of platelet anticoagulant and platelet activating agent and blood taking needle and silica gel hose (10) of infusing,
Wherein, described injection device (3) comprises,
Injection tube (31), its entirety is cylindrical, and inside is provided with and holds cavity (311), and is provided with the tip (312) be communicated with described accommodation cavity (311) in the upper end of described injection tube (31);
Propulsion plant (32), it is movably set in described accommodation cavity (311) in the mode that can vertically move, described propulsion plant (32) comprises piston head (321) and pushing ram (322), and described pushing ram (322) is flexibly connected with the lower end of described piston head (321), free dismounting can be carried out.
2. according to the test kit of rapid extraction blood plasma described in claim 1, it is characterized in that, described piston head (321) comprising: soft rubber head (3211) and be positioned at described soft rubber head (3211) below, and the hard connecting portion (3212) be fixedly connected with described soft rubber head (3211), described soft rubber head (3211) is at least provided with 3 circle sealing rings.
3. according to the test kit of rapid extraction blood plasma described in claim 1, it is characterized in that: in described memory block, be also placed with cap head (11), tip (312) outer cover of described injection tube (31) is equipped with connecting cylinder (313), and the lower end of described connecting cylinder (313) is fixedly connected with described injection tube (31); The size of described cap head (11) is mated with the size of described connecting cylinder (313).
4. according to the test kit of rapid extraction blood plasma described in claim 1, it is characterized in that: in described memory block, be also placed with back cover lid (12), the front cover (122) that described back cover lid (12) comprises closure part (121) and is fixedly connected with described closure part (121) lower end; Described closure part (121) is cylinder, and the diameter of its diameter and described accommodation cavity (311) matches; Described front cover (122) is circular, and its diameter is greater than/equals the external diameter of described injection tube (31).
5. according to the test kit of rapid extraction blood plasma described in claim 4, it is characterized in that: in described back cover lid (12), closure part (121) is hollow cylinder, and the top (1211) of described closure part (121) progressively reduces along its axial bore from the bottom to top, and top (12111) caliber size of described closure part (121) is mated with hard connecting portion (3212) size in described piston head (321).
6. according to the test kit of rapid extraction blood plasma described in claim 5, it is characterized in that: in described back cover lid (12), the height of closure part (121) equals/be greater than the height of hard connecting portion (3212) in described piston head (321).
7. according to the test kit of rapid extraction blood plasma described in claim 1, it is characterized in that: in described memory block, be also placed with pedestal (13), described pedestal (13) is provided with groove (131), the size of described groove (131) and the bottom size of described pushing ram (322) match.
8. according to the test kit of rapid extraction blood plasma described in claim 1, it is characterized in that: in described memory block, be also placed with tee T (14).
9. according to the test kit of rapid extraction blood plasma described in claim 1, it is characterized in that: the number of described conventional syringe (4) is 3 wherein, having the volume of 2 conventional syringe (4) identical, be all less than the volume of another conventional syringe (4).
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106754681A (en) * | 2016-12-29 | 2017-05-31 | 李众利 | A kind of platelet rich plasma and preparation method and application |
| CN109692761A (en) * | 2018-12-25 | 2019-04-30 | 山东博森医学工程技术有限公司 | A kind of platelet rich plasma extraction element and its method |
| CN111420813A (en) * | 2020-04-06 | 2020-07-17 | 四川大学华西医院 | PRP centrifugal sleeve, PRP centrifugal machine and PRP preparation method |
| WO2021098011A1 (en) * | 2019-11-21 | 2021-05-27 | 四川我爱我来汽车俱乐部有限公司 | Method for comprehensively extracting autologous leukocytes and platelet plasma |
-
2014
- 2014-11-19 CN CN201420700817.5U patent/CN204233506U/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106754681A (en) * | 2016-12-29 | 2017-05-31 | 李众利 | A kind of platelet rich plasma and preparation method and application |
| CN106754681B (en) * | 2016-12-29 | 2018-04-13 | 李众利 | A kind of platelet rich plasma and preparation method and application |
| CN109692761A (en) * | 2018-12-25 | 2019-04-30 | 山东博森医学工程技术有限公司 | A kind of platelet rich plasma extraction element and its method |
| WO2021098011A1 (en) * | 2019-11-21 | 2021-05-27 | 四川我爱我来汽车俱乐部有限公司 | Method for comprehensively extracting autologous leukocytes and platelet plasma |
| CN111420813A (en) * | 2020-04-06 | 2020-07-17 | 四川大学华西医院 | PRP centrifugal sleeve, PRP centrifugal machine and PRP preparation method |
| CN111420813B (en) * | 2020-04-06 | 2022-01-28 | 四川大学华西医院 | PRP centrifugal sleeve, PRP centrifugal machine and PRP preparation method |
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