CN204233515U - A kind of extraction element of blood plasma - Google Patents
A kind of extraction element of blood plasma Download PDFInfo
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- CN204233515U CN204233515U CN201420697182.8U CN201420697182U CN204233515U CN 204233515 U CN204233515 U CN 204233515U CN 201420697182 U CN201420697182 U CN 201420697182U CN 204233515 U CN204233515 U CN 204233515U
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Abstract
The utility model discloses a kind of extraction element of blood plasma, the extraction element of described blood plasma, comprise: injection tube (1), its entirety is cylindrical, inside is provided with and holds cavity (11), and is provided with the tip (12) be communicated with described accommodation cavity (11) in the upper end of described injection tube (1); Propulsion plant (2), it is movably set in described accommodation cavity (11) in the mode that can vertically move, described propulsion plant (2) comprises piston head (21) and pushing ram (22), and described pushing ram (22) is flexibly connected with the lower end of described piston head (21), free dismounting can be carried out; Have structure simple, easy to operate, cost of manufacture is cheap, pollutes the advantages such as few.
Description
Technical field
This utility model relates to clinical medicine domain, specifically provides a kind of extraction element of blood plasma.
Background technology
Platelet rich plasma (platelet-rich plasma, PRP) be fresh anticoagulated whole blood after certain condition is centrifugal, the blood plasma that separation and Extraction is higher than platelet content in normal whole blood 4 ~ 6 times.
The people such as the 80's of last century DAVID R. KNIGHTON have found that platelet can promote blood vessel hyperplasia, collage synthesis, scientist studies the PRP confirming and extract from human plasma further subsequently, containing more than 400 kinds of somatomedin, as: platelet derived growth factor (platelet-derived growthfactor, PDGF), transforming growth factor-β (transforming growth factor, TGF-β), VEGF (vascularendothelial growth factor, VEGF), epidermal growth factor (vascularendothelial growthfactor, EGF), para-insulin like growth factor (insulin-like growthfactor, IGF), fibroblast growth factor (fibroblast growth factor, FGF) etc.The somatomedin in these platelet source, can attract macrophage, mescenchymal stem cell and osteoblast etc., and play an important role to the Differentiation and proliferation of cell, have obvious facilitation to wound healing, reparation and regeneration.As wherein PDGF, TGF-β is conducive to stimulating skeletonization, accelerated bone reparation, play an important role in union of fracture.PRP also can be used for treating the thrombocytopenia that causes of a variety of causes and hemorrhage, and accelerating wound healing.Research also finds that the platelet of PRP middle and high concentration effectively can improve propagation and the differentiation capability of stem cell, and significantly can increase the synthesis of fibroblastic propagation and I-type collagen.Therefore be effectively separated and improve hematoblastic concentration in PRP and become the key of whole PRP therapeutic scheme.
The preparation of current PRP is praised highly and is extracted from patient's self-blood, because this has many good qualities: as abundance, draw materials conveniently and preparation method is simple, body absorption fast, self PRP it also avoid virus disseminating and immunologic rejection problem simultaneously, fool proof, therefore PRP is widely applied in different medical domains, as orthopaedics, the department of stomatology, decorative sursery, sports medical science and aesthetic medicine etc.
Developing rapidly of this field, occurred the apparatus of a lot of preparation PRP, its ultimate principle mainly utilizes the difference in blood on various composition proportion, and the sedimentation velocity caused is different thereupon, by centrifugal by blood layering, these methods can be divided into again manual method (centrifuging and secondary centrifuging method) and instrument preparation method, as gathered the machine of PRP, as the HARVEST I of the U.S., II etc., but their prevailing prices are expensive, need special consumptive material, limited during use.Secondary centrifuging method also exists that complicated operation, process are very long, the risk of contamination of products, and platelet in PRP is more fragile in vitro and easily activate, too high centrifugal speed and the centrifugal number of times of increase, capital make platelet membrane break reduce its biological activity, cause hematoblastic loss, and then in individuation clinical practice and be cosmetically restricted.
In blood, separation energy is extracted outside PRP, also has the platelet poor plasma (Platelet Poor Plasma, PPP) of upper strata more, though PPP does not have, PRP's is powerful, and recent research confirms, PPP is also a rare resource, cosmetically autologous, PPP has unique effect.PPP is in heating or after adding the reagent such as calcium and thrombin Gu Yuan process, can be made into the protein filled thing of autologous collagen, adopt tiny needle set to be injected at subcutaneous layer of fat, cosmetically can have following subject range: fill all kinds of wrinkle, sculpture type body, fill recessed scar, solve two chivalrous depression, modify chin profile, rich buccal, to fill below eye depression and improve other tissue site profiles etc." hyaluronic acid " that the autologous collagen albumen be made up of PPP is conventional compared with beauty parlor and " collagen protein " injectant, client Geng Yi accepts, because this is from autologous, be not external medicine (foreign body), almost without swelling after injection, anaphylaxis, can take effect at once.
And at present still not about while separation and Extraction PRP and PPP device, find convenient and swift, high purity concentrations, cheap, be suitable for the extraction equipment of national conditions PRP and PPP, remain the target that people pursue.
Utility model content
Given this, the purpose of this utility model is the extraction element providing a kind of blood plasma, at least to solve blood plasma extraction element complex structure in the past, expensive, needs special consumptive material, limited during use, is easily subject to the problems such as outside contamination.
This utility model provides a kind of extraction element of blood plasma, it is characterized in that, comprising:
Injection tube 1, its entirety is cylindrical, and inside is provided with and holds cavity 11, and is provided with the tip 12 be communicated with described accommodation cavity 11 in the upper end of described injection tube 1;
Propulsion plant 2, it is movably set in described accommodation cavity 11 in the mode that can vertically move, and described propulsion plant 2 comprises piston head 21 and pushing ram 22, and described pushing ram 22 is flexibly connected with the lower end of described piston head 21, can carry out free dismounting.
Preferably, described piston head 21 comprises: soft rubber head 211 and being positioned at below described soft rubber head 211, and the hard connecting portion 212 be fixedly connected with described soft rubber head 211, described soft rubber head 211 is at least provided with 3 circle sealing rings.
Further preferably, tip 12 outer cover of described injection tube 1 is equipped with connecting cylinder 13, and the lower end of described connecting cylinder 13 is fixedly connected with described injection tube 1, and described connecting cylinder 13 is movably installed with cap head 14.
Further preferably, the extraction element of described blood plasma also comprises: back cover lid 3, the front cover 32 that described back cover lid 3 comprises closure part 31 and is fixedly connected with lower end, described closure part 31; Described closure part 31 is cylinder, and the diameter of its diameter and described accommodation cavity 11 matches; Described front cover 32 is circular, and its diameter is greater than/equals the external diameter of described injection tube 1.
Further preferably, in described back cover lid 3, closure part 31 is hollow cylinder, and the top 311 of described closure part 31 progressively reduces along its axial bore from the bottom to top, and top 3111 caliber size of described closure part 31 is mated with hard connecting portion 212 size in described piston head 21.
Further preferably, in described back cover lid 3, the height of closure part 31 equals/is greater than the height of hard connecting portion 212 in described piston head 21.
Further preferably, the extraction element of described blood plasma also comprises pedestal 4, and described pedestal 4 is provided with groove 41, and the size of described groove 41 and the bottom size of described pushing ram 22 match.
Further preferably, the extraction element of described blood plasma also comprises tee T 5, the free end of the first branch road 51 of described tee T 5 can be flexibly connected with the tip 12 of described injection tube 1, the free end of the second branch road 52 of described tee T 5 is connected with the first syringe, the free end of the 3rd branch road 53 of described tee T 5 is connected with the second syringe, and the intersection of described first branch road 51, second branch road 52 and the 3rd branch road 53 is provided with coupling cock 54.
This utility model provides blood plasma extraction element, and conventional syringe has been carried out structure improvement by it, has centrifuge tube and syringe two kinds of functions concurrently to realize it.First, it has injection tube and propulsion plant, vertically moving, can realize the function of its syringe, completing blood of human body sampling by promoting propulsion plant in the accommodation cavity of injection tube; Secondly, the injection tube of conventional syringe has been carried out structure improvement by this utility model, eliminate the outer rim that its lower end extends laterally, can mate to greatest extent with centrifuge, more convenient and stable when centrifugal, also propulsion plant is designed to split-type structural simultaneously, when carrying out centrifugal, pushing ram in propulsion plant can be removed, stability when ensureing centrifugal further, realizes the effect of its centrifuge tube.
The blood plasma extraction element that this utility model provides, have structure simple, easy to operate, cost of manufacture is cheap, pollutes the advantages such as few.
Accompanying drawing explanation
Fig. 1 is the structural representation of the extraction element a state of blood plasma;
Fig. 2 is the structural representation of propulsion plant;
Fig. 3 is the structural representation of cap head;
Fig. 4 is the structural representation of back cover lid;
Fig. 5 is the structural representation of the extraction element b state of blood plasma;
Fig. 6 is the structural representation of pedestal;
Fig. 7 is the structural representation of tee T, and wherein, arrow represents blood and flows to.
Detailed description of the invention
Further illustrate content of the present utility model with specific embodiment below, but should not be construed as restriction of the present utility model.When not deviating from this utility model spirit and essence, the amendment do this utility model method, step or condition or replacement, all belong to scope of the present utility model.
If do not specialize, the conventional means that technological means used in embodiment is well known to those skilled in the art.
See the extraction element that Fig. 1 is a kind of blood plasma, it has syringe and centrifuge tube two kinds of functions concurrently simultaneously, comprise injection tube 1 and propulsion plant 2, wherein, in order to realize the function of its centrifuge tube, the size of injection tube 1 is conveniently enable to match with numerous centrifuge, simultaneously also in order to improve centrifugal degree of stability when carrying out centrifugal blood, the outer rim extended laterally conventional injection cylinder 1 lower end is removed, make the entirety of injection tube 1 cylindrical, be provided with in the inside of injection tube 1 and hold cavity 11, also be provided with the tip 12 be communicated with described accommodation cavity 11 in the upper end of injection tube 1 simultaneously, this tip 12 can be used for syringe needle or various connection tube connects, realize extraction or the separation function of injection tube 1, this injection tube can select 2ml, 5ml, 20ml, 30ml and 50ml all size, meet the demand of different situations, facilitate clinical practice, easily especially to promote the use of at middle and small hospital and beauty parlor, and propulsion plant 2, see Fig. 1 and Fig. 2, it comprises piston head 21 and pushing ram 22, and pushing ram 22 is flexibly connected with the lower end of piston head 21, can carry out free dismounting, wherein, piston head 21 can be selected multiple with the movable connection method of pushing ram 22, as being threaded, buckle connection, push button connection etc., this propulsion plant 2 entirety is movably set in described accommodation cavity 11 in the mode that can vertically move simultaneously.
The specific works process of the extraction element of this blood plasma is: 1, blood draw, the tip of injection tube is connected with intravenous transfusion device connection tube, and the other end of intravenous transfusion device connection tube is connected with intravenous infusion apparatus needle, or the tip of intravenous infusion apparatus needle direct injection cylinder is connected, pass propulsion plant backward, realize blood draw, realize the function of its syringe.2, centrifugal blood, after blood draw terminates, continues to pass propulsion plant backward, until piston head is moved to appropriate location, pushing ram and piston head are dismantled, after taking out pushing ram, injection tube is put into centrifuge and carries out centrifugal blood, make blood layering, then carry out follow-up mask work.
In order to improve the connection between piston head 21 and pushing ram 22, as improvement, see Fig. 2, piston head 21 be designed to soft rubber head 211 and be positioned at below soft rubber head 211, and the hard connecting portion 212 be fixedly connected with soft rubber head 211, described soft rubber head 211 is at least provided with 3 circle sealing rings, wherein, the object of soft rubber head 211 is that it both can realize the shutoff of injection tube 1, can also move freely in the accommodation cavity 11 of injection tube 1 simultaneously, and the connection of conveniently pushing ram 22 and its lower end, lower end is designed to hard connecting portion and makes it have impetus, a kind of connected mode is as shown in Figure 2, the below of hard connecting portion 211 is provided with tapped blind hole, the upper end of pushing ram is provided with threaded rod, by coordinating of threaded rod and tapped blind hole, realize being flexibly connected of piston head and pushing ram, because the mode be flexibly connected has multiple, here just do not enumerate, and the sealing ring on soft rubber head refers to that the periphery along soft rubber head is arranged, sealing circle connects with the inwall holding cavity, and described 3 circles set gradually along the axis of soft rubber head, this design is strengthened than the sealing ring of conventional rubber plug, prevent injection tube when centrifugal action, the phenomenon that blood leaks outside occurs.
And when using this blood extraction device to carry out blood extraction, in order to avoid outside contamination as far as possible, as the improvement of technical scheme, see Fig. 1, in tip 12 outer cover of injection tube 1, connecting cylinder 13 is housed, the lower end of described connecting cylinder 13 is fixedly connected with described injection tube 1, and on connecting cylinder 13, be movably installed with cap head 14, see Fig. 5, by using cap head by most advanced and sophisticated 12 shutoff, reasonable with the external world, namely after blood drawing terminates, use cap head by most advanced and sophisticated shutoff at once, avoid the pollution of blood, the extraction quality of the blood of raising.And the connected mode of connecting cylinder and cap head, can select to be provided with screw thread on the lateral wall of connecting cylinder, the medial wall of cap head is also provided with screw thread, the two is threaded connection, certainly the two by being respectively arranged with the form of groove/land on sidewall, can also carry out buckle connection, as long as do not drop when ensureing centrifugal, effective preventing pollution.See Fig. 3, be a kind of structure of cap head, its top is hemispherical, and its underpart is coordinate with connecting cylinder cylindrical.
During owing to carrying out centrifugal blood, due to the effect of centrifugal force, piston head can be moved, leak, bring difficulty for centrifugal, for solving this problem, as the improvement of scheme, back cover lid 3 can be had additional on the extraction element of blood plasma see Fig. 5, see Fig. 4, the front cover 32 that this back cover lid 3 comprises closure part 31 and is fixedly connected with lower end, described closure part 31; Wherein closure part 31 is cylinder, and the diameter of its diameter and described accommodation cavity 11 matches, and holds in cavity for being plugged in; Front cover 32 is designed to circle simultaneously, its diameter is greater than/equals the external diameter of described injection tube 1, back cover lid is enable just to be positioned in the bottom of concentrator bowl, can piston head be plugged in bottom injection tube on the one hand, expand centrifugal volume, keep volumetric blood constant, and strengthen piston head, ensure and not leaked outside when centrifugal, prevented the accident of piston to drop simultaneously, stable when ensureing centrifugal.
In order to improve stability when back cover lid 3 carries out back cover further, see Fig. 5, be hollow cylinder by closure part in back cover lid 3 31, and the top 311 of described closure part 31 progressively reduces along its axial bore from the bottom to top, and top 3111 caliber size of described closure part 31 is mated with hard connecting portion 212 size in described piston head 21, hard connecting portion is positioned in closure part just, prevent it from producing when centrifugal and rock or move, but, be more preferably the height being designed to the height of closure part 31 in back cover lid 3 to equal/be greater than hard connecting portion 212 in described piston head 21, hard connecting portion is contained in closure part completely.
But, conveniently operate, the extraction element of this blood plasma also comprises pedestal 4, see Fig. 6, this pedestal 4 is provided with groove 41, the size of described groove 41 and the bottom size of described pushing ram 22 match, conveniently the extraction element of blood plasma is inverted, the bottom of pushing ram is fixed on this pedestal, to carry out the subsequent step operation of blood extraction, this pedestal can be made into single circle, also can be made into the bar shaped of putting multiple syringe, available plastics or metal are made, and see Fig. 6 only for a single circle.
In order to further facilitate the separation and Extraction of blood, the extraction element of this blood plasma also comprises tee T 5, the free end of the first branch road 51 of described tee T 5 can be flexibly connected with the tip 12 of described injection tube 1, the free end of the second branch road 52 of described tee T 5 is connected with the first syringe, the free end of the 3rd branch road 53 of described tee T 5 is connected with the second syringe, and described first branch road 51, the intersection of the second branch road 52 and the 3rd branch road 53 is provided with coupling cock 54, thus can realize completing the separation and Extraction to PPP and PRP simultaneously, whole operation is closed and is carried out, reduce the risk of blood contamination, ensure the quality of blood.And the concrete structure of tee T, visible Fig. 7.
The extraction element of above blood plasma is that the mode of going forward one by one carries out writing, and highlights the difference of each embodiment, and its similar portion can cross-reference, the not solution of influence technique problem and the generation of technique effect.
Claims (8)
1. an extraction element for blood plasma, is characterized in that, comprising:
Injection tube (1), its entirety is cylindrical, and inside is provided with and holds cavity (11), and is provided with the tip (12) be communicated with described accommodation cavity (11) in the upper end of described injection tube (1);
Propulsion plant (2), it is movably set in described accommodation cavity (11) in the mode that can vertically move, described propulsion plant (2) comprises piston head (21) and pushing ram (22), and described pushing ram (22) is flexibly connected with the lower end of described piston head (21), free dismounting can be carried out.
2. according to the extraction element of blood plasma described in claim 1, it is characterized in that, described piston head (21) comprising: soft rubber head (211) and be positioned at described soft rubber head (211) below, and the hard connecting portion (212) be fixedly connected with described soft rubber head (211), described soft rubber head (211) is at least provided with 3 circle sealing rings.
3. according to the extraction element of blood plasma described in claim 1, it is characterized in that: tip (12) outer cover of described injection tube (1) is equipped with connecting cylinder (13), the lower end of described connecting cylinder (13) is fixedly connected with described injection tube (1), and described connecting cylinder (13) is movably installed with cap head (14).
4. according to the extraction element of blood plasma described in claim 2, it is characterized in that, also comprise: back cover lid (3), the front cover (32) that described back cover lid (3) comprises closure part (31) and is fixedly connected with described closure part (31) lower end; Described closure part (31) is cylinder, and the diameter of its diameter and described accommodation cavity (11) matches; Described front cover (32) is circular, and its diameter is greater than/equals the external diameter of described injection tube (1).
5. according to the extraction element of blood plasma described in claim 4, it is characterized in that: in described back cover lid (3), closure part (31) is hollow cylinder, and the top (311) of described closure part (31) progressively reduces along its axial bore from the bottom to top, and top (3111) caliber size of described closure part (31) is mated with hard connecting portion (212) size in described piston head (21).
6. according to the extraction element of blood plasma described in claim 5, it is characterized in that: in described back cover lid (3), the height of closure part (31) equals/be greater than the height of hard connecting portion (212) in described piston head (21).
7. according to the extraction element of blood plasma described in claim 1, it is characterized in that: also comprise pedestal (4), described pedestal (4) is provided with groove (41), the size of described groove (41) and the bottom size of described pushing ram (22) match.
8. according to the extraction element of blood plasma described in claim 1, it is characterized in that: also comprise tee T (5), the free end of first branch road (51) of described tee T (5) can be flexibly connected with the tip of described injection tube (1) (12), the free end of second branch road (52) of described tee T (5) is connected with the first syringe, the free end of the 3rd branch road (53) of described tee T (5) is connected with the second syringe, and described first branch road (51), the intersection of the second branch road (52) and the 3rd branch road (53) is provided with coupling cock (54).
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| Application Number | Priority Date | Filing Date | Title |
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| CN201420697182.8U CN204233515U (en) | 2014-11-19 | 2014-11-19 | A kind of extraction element of blood plasma |
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| CN201420697182.8U CN204233515U (en) | 2014-11-19 | 2014-11-19 | A kind of extraction element of blood plasma |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491944A (en) * | 2014-11-19 | 2015-04-08 | 沈阳优吉诺生物科技有限公司 | Plasma extracting device and extracting method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491944A (en) * | 2014-11-19 | 2015-04-08 | 沈阳优吉诺生物科技有限公司 | Plasma extracting device and extracting method thereof |
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