CN204121449U - Utilize the equipment of the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI - Google Patents
Utilize the equipment of the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI Download PDFInfo
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- CN204121449U CN204121449U CN201420479756.4U CN201420479756U CN204121449U CN 204121449 U CN204121449 U CN 204121449U CN 201420479756 U CN201420479756 U CN 201420479756U CN 204121449 U CN204121449 U CN 204121449U
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Abstract
The utility model discloses a kind of equipment utilizing the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI, it relates to the fermentation technique adding Chinese medicine in a kind of microbial reproduction process.It comprises multiple original bacteria liquid bottle, triangular flask, clip, support, spring, and multiple original bacteria liquid bottle is connected with triangular flask respectively by inclined-plane, and triangular flask is fixed on support by clip, and support is provided with spring, and spring contacts with triangular flask and connects.This utility model utilizes composite bacteria fermented tcm to produce microbiological Chinese traditional medicine preparation, with the Chinese medicinal formulae of fermentable, produce and a kind ofly replace antibiotic no drug residue, prophyiaxis and promoting growth, Chinese medicine microorganism formulation with low cost completely, device structure is simple, practical.
Description
Technical field
The utility model relates to the fermentation technique adding Chinese medicine in a kind of microbial reproduction process, be specifically related to a kind of equipment utilizing the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI.
Background technology
Microbiological Chinese traditional medicine combines with traditional method of Chinese medicinal with modern biotechnology, makes the modernization of production Chinese medicine technique, make up the deficiency of traditional method for making.Biological bacteria fermentation technique is applied in Chinese medicine development, makes the effective macromole of medicine Absorbable rod become micromolecule and be more easily absorbed by the body, more easily arrive target organ and play a role.Thus improve drug effect and the bioavailability of medicine.Moreover, in the Chinese medicine preparation that applying biological bacterium fermentation technology is produced, not only containing the physiologically active ingredient extracting useful effect in Chinese medicine, but also be rich in the trace element of multivitamin, abundant aminoacid and the multiple beneficial that strain and substrate produce in fermentation preparation process.These nutritional labeling components are reasonable, very easily absorbed by body and utilize.Microorganism simultaneously adds Chinese medicine in reproductive process, has carried out directed screening, allow microorganism and by-product thereof give expression to the characteristic of a part of Chinese medicine to microorganism.So adopt the Chinese medicine preparation of this explained hereafter, show the Overlay of Tiny ecosystem and Chinese medicine, more meet the needs of.
Utility model content
For the deficiency that prior art exists, this utility model object is to provide a kind of equipment utilizing the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI, composite bacteria fermented tcm is utilized to produce microbiological Chinese traditional medicine preparation, with the Chinese medicinal formulae of fermentable, produce and a kind ofly replace antibiotic no drug residue, prophyiaxis and promoting growth, Chinese medicine microorganism formulation with low cost completely, device structure is simple, practical.
To achieve these goals, this utility model realizes by the following technical solutions: the equipment utilizing the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI, comprise multiple original bacteria liquid bottle, triangular flask, clip, support, spring, multiple original bacteria liquid bottle is connected with triangular flask respectively by inclined-plane, triangular flask is fixed on support by clip, support is provided with spring, and spring contacts with triangular flask and connects.
Described utilizes in the culture medium of the fermentation preparation of the equipment of the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI containing Chinese medicinal components, parts by weight and the additional proportion of each raw material of described Chinese herbal medicine are: the composition such as the Radix Astragali (processing), Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Glycyrrhizae (processing), Radix Angelicae Sinensis, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae, Radix Bupleuri, the parts by weight of various Chinese medicine are: the Radix Astragali (processing) 75 parts, Radix Codonopsis 60 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 60 parts, 30 parts, Radix Glycyrrhizae (processing), Radix Angelicae Sinensis 30 parts, Pericarpium Citri Reticulatae 20 parts, Rhizoma Cimicifugae 20 parts, Radix Bupleuri 20 parts.
The function of each medicine of Chinese medicinal components described in the utility model is: Radix Astragali sweet in the mouth is warm in nature, tonifying Qi and lifting yang, and its active component astragalus polysaccharides can improve immunity of organisms; Radix Codonopsis sweet in the mouth is flat, invigorating the spleen and replenishing QI and taste, and its active component Saponin can improve immunity of organisms; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic, immunity moderation function, its active component is volatile ingredient and atractylodes lactone constituents, methods of glycosides and polysaccharide composition; Radix Angelicae Sinensis sweet in the mouth is warm in nature, can enrich blood, and can invigorate blood circulation again, and its active component sodium ferulate energy activating macrophage, plays immunologic function; Radix Glycyrrhizae has heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription, and its active component glycyrrhizic acid is cell immunomodulator; Pericarpium Citri Reticulatae circulation of qi promoting spleen invigorating, whets the appetite in tune, and its active component volatile oil, hesperidin have the function of facilitating digestion liquid secretion, appetite stimulator; Massa Medicata Fermentata spleen invigorating acaricide, stimulating appetite; The Rhizoma Atractylodis Macrocephalae; Rhizoma Cimicifugae promotes yang-energy, antipyretic-antalgic, strengthens and exempts from function; Radix Bupleuri is evacuated and is brought down a fever, Shu Gan yang invigorating.
Fermentation process of the present utility model:
(1), adopt composite bacteria solid fermentation strain fermentation, the composite bacteria solid fermentation strain adopted is: bacillus subtilis, bacillus amyloliquefaciens, Bacillus licheniformis, beer yeast, produce Ruan's candida mycoderma, aspergillus niger, Bush's lactobacillus, bacillus acidophilus and bacillus bifidus, the inoculum concentration of original bacteria liquid is 4%, the inoculative proportion of each strain is: bacillus subtilis 10 ~ 15%, bacillus amyloliquefaciens 10 ~ 15%, Bacillus licheniformis 10 ~ 15%, beer yeast 10 ~ 15%, produce Ruan's candida mycoderma 10 ~ 15%, aspergillus niger 10 ~ 15%, Bush's lactobacillus 10 ~ 15%, bacillus acidophilus 10 ~ 15%, bacillus bifidus 10 ~ 15%,
(2), by the original bacteria liquid of the bacillus subtilis after purifying, bacillus amyloliquefaciens and Bacillus licheniformis, from inclined-plane access triangular flask, shaken cultivation 24 hours;
(3), by rear beer yeast of purifying, the original bacteria liquid producing Ruan's candida mycoderma and aspergillus niger, from inclined-plane access triangular flask, shaken cultivation 48 hours;
(4), by the original bacteria liquid of the Bush's lactobacillus after purifying, bacillus acidophilus and bacillus bifidus, from inclined-plane access Kolle flask, temperature controls 37 DEG C, cultivates 24 hours;
(5), fermented tcm culture medium adopts brown sugar, Chinese medicinal components, potassium dihydrogen phosphate, yeast extract, each Composition Weight Parts and additional proportion are: brown sugar 3 ~ 5%, Chinese medicinal components 1 ~ 2%, potassium dihydrogen phosphate 0.2%, yeast extract 0.5%, surplus is water, pH value nature, temperature controls at 121 DEG C, sterilizing 20 minutes, inoculate when being cooled to 30 DEG C, inoculum concentration is 5 ~ 10%;
(6), the control of fermentation condition
Adopt anaerobic fermentation, rotating speed 180r/min, temperature 32 DEG C, fermentation time 48 ~ 72 hours, when pH value reaches 4.0, is fermentation termination.
The former strain of various bacterium described in the utility model, all introduces from Chinese General Microbiological Culture preservation administrative center (CGMCC) or agriculture Microbiological Culture Collection administrative center (ACCC), ensure that survival and the quality of each strain.
The beneficial effects of the utility model are: fall apart with compound bacteria-fermented invigorating the spleen and replenishing QI, are a kind ofly to replace antibiotic no drug residue, prophyiaxis and promoting growth, Chinese medicine microecological preparation with low cost completely.Because invigorating the spleen and replenishing QI is fallen apart with compound bacteria to immune synergism, therefore its immunocompetence of additive of the scattered product of compound bacteria-fermented invigorating the spleen and replenishing QI is considerably beyond other series products, and this Preparation equipment is effective, the original bacteria liquid that can conveniently vibrate is cultivated, and ferment effect is good.
Accompanying drawing explanation
This utility model is described in detail below in conjunction with the drawings and specific embodiments;
Fig. 1 is structural representation of the present utility model.
Detailed description of the invention
The technological means realized for making this utility model, creation characteristic, reaching object and effect is easy to understand, below in conjunction with detailed description of the invention, setting forth this utility model further.
With reference to Fig. 1, this detailed description of the invention is by the following technical solutions: utilize composite bacteria to ferment the equipment of the scattered producing microbial Chinese medicine of invigorating the spleen and replenishing QI, comprise multiple original bacteria liquid bottle A, triangular flask B, clip C, support D, spring E, multiple original bacteria liquid bottle A is connected with triangular flask B respectively by inclined-plane, triangular flask B is fixed on support D by clip C, support D is provided with spring E, spring E contacts with triangular flask B and connects.
Embodiment 1: the optimum ratio choosing each raw material in medicament is: the Radix Astragali (processing) 75 parts, Radix Codonopsis 60 parts, the Rhizoma Atractylodis Macrocephalae (stir-fry) 60 parts, 30 parts, Radix Glycyrrhizae (processing), Radix Angelicae Sinensis 30 parts, Pericarpium Citri Reticulatae 20 parts, Rhizoma Cimicifugae 20 parts, Radix Bupleuri 20 parts.
The cultivation of microorganism original seed that fermentation invigorating the spleen and replenishing QI is fallen apart and the cultivation of seed liquor: by the bacillus subtilis after purification, the original bacteria liquid of bacillus amyloliquefaciens and Bacillus licheniformis, shaken cultivation 24 hours from inclined-plane access triangular flask, by the beer yeast after purification, produce the original bacteria liquid of Ruan's candida mycoderma and aspergillus niger, triangular flask shaken cultivation 48 hours are accessed from inclined-plane, by the Bush's lactobacillus after purification, the original bacteria liquid of bacillus acidophilus and bacillus bifidus, from inclined-plane access Kolle flask, temperature controls at 37 DEG C, cultivate 24 hours, original bacteria liquid inoculum concentration is 4%, inoculate in following ratio:
The preparation method of fermented tcm culture medium:
Brown sugar 3 ~ 5%, Chinese medicinal components 1 ~ 2%, potassium dihydrogen phosphate 0.2%, yeast extract 0.5%, surplus is water, and pH value nature, temperature controls at 121 DEG C, sterilizing 20 minutes, and be cooled to 30 DEG C of inoculations, inoculum concentration is 5 ~ 10%.
The control of fermentation condition:
Adopt anaerobic fermentation, rotating speed 180r/min, temperature 32 DEG C, fermentation time 48 ~ 72 hours, when pH value reaches 4.0, is fermentation termination.
More than show and describe ultimate principle of the present utility model and principal character and advantage of the present utility model.The technical staff of the industry should understand; this utility model is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present utility model; under the prerequisite not departing from this utility model spirit and scope; this utility model also has various changes and modifications, and these changes and improvements all fall within the scope of claimed this utility model.The claimed scope of this utility model is defined by appending claims and equivalent thereof.
Claims (1)
1. utilize the equipment of the scattered producing microbial Chinese medicine of composite bacteria fermentation invigorating the spleen and replenishing QI, comprise multiple original bacteria liquid bottle (A), triangular flask (B), clip (C), support (D), spring (E), multiple original bacteria liquid bottle (A) is connected with triangular flask (B) respectively by inclined-plane, triangular flask (B) is fixed on support (D) by clip (C), support (D) is provided with spring (E), spring (E) contacts with triangular flask (B) and connects.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106619941A (en) * | 2017-02-27 | 2017-05-10 | 哈尔滨中科生物工程有限公司 | Traditional Chinese medicine fermented preparation for improving production performance of sows, preparation method and application thereof |
CN113827641A (en) * | 2021-09-24 | 2021-12-24 | 武汉华扬动物药业有限责任公司 | Traditional Chinese medicine immunomodulator, preparation method and application |
-
2014
- 2014-08-25 CN CN201420479756.4U patent/CN204121449U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106619941A (en) * | 2017-02-27 | 2017-05-10 | 哈尔滨中科生物工程有限公司 | Traditional Chinese medicine fermented preparation for improving production performance of sows, preparation method and application thereof |
CN113827641A (en) * | 2021-09-24 | 2021-12-24 | 武汉华扬动物药业有限责任公司 | Traditional Chinese medicine immunomodulator, preparation method and application |
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Granted publication date: 20150128 Termination date: 20150825 |
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