CN200986546Y - Novel enzymatic chemiluminescence immunity detection system - Google Patents
Novel enzymatic chemiluminescence immunity detection system Download PDFInfo
- Publication number
- CN200986546Y CN200986546Y CN 200620135141 CN200620135141U CN200986546Y CN 200986546 Y CN200986546 Y CN 200986546Y CN 200620135141 CN200620135141 CN 200620135141 CN 200620135141 U CN200620135141 U CN 200620135141U CN 200986546 Y CN200986546 Y CN 200986546Y
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- China
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- detection system
- chemiluminescence
- novel enzyme
- immune detection
- catalyzed
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Abstract
The utility model belongs to the field of medical diagnosis and detection technologies, and discloses a novel enzyme-aided chemiluminescence immune detection system. A frame is orderly provided with a series of in-vitro diagnosis kits, a vibrator, an isothermal incubation device, a plate washing device, a chemiluminescence detection device and a fitted control and analysis managing device. No hazardous reagent is used in the test with this utility model, which prevents pollution and injury to operators of radionuclide, and greatly shortens detection period. The utility model is characterized in high sensitivity, easy operation and convenient standardized operation, and can be used for biology and medicine research and clinical test diagnosis.
Description
Technical field
The utility model belongs to medical diagnosis detection technique field, particularly a kind of novel enzyme-catalyzed chemiluminescence immune detection system.
Background technology
Existing clinical vitro detection adopts radio immunoassay more, the checkout equipment complexity that this method is used, and must use radioactively labelled substance owing to put the method for exempting from, must measure testing result with special radioactivity seeker, operating personnel are also had radioactive contamination and injury, short nucleic of half life period such as Chang Yong iodine-125, iodine-131 and phosphorus-32 simultaneously, its holding time is short, bring inconvenience also for clinical use, seriously limited the application of radiommunoassay equipment in clinical diagnosis.Also has a kind of novel detection method--chemiluminescence immunoassay, this method is used chemiluminescence detector, this instrument has high sensitivity, easy and simple to handle, characteristics fast, be easy to normalizing operation, and do not use harmful reagent in the test, the reagent long shelf-life, but this instrument can only detect, can not carry out data analysis and data management, hinder the popularization of luminescent detection techniques.
The utility model content
The purpose of this utility model provides a kind of safe, novel enzyme-catalyzed chemiluminescence immune detection system easily and fast.
The utility model is realized above-mentioned purpose by the following technical solutions: a kind of novel enzyme-catalyzed chemiluminescence immune detection system, the control and the analysis management device that be placed with serial external diagnosis reagent case, oscillator, constant temperature incubation device on the frame successively, wash panel assembly, chemiluminescence detecting reach cooperation with it.
Control and analysis management device comprise computing machine, display, printer, keyboard, and wherein computing machine connects output terminal, the input end of chemiluminescence detecting, and display, printer connect fanout respectively, and keyboard connects the computing machine input end.
The series external diagnosis reagent case comprises box body, and immune response microwell plate and detectable bottle are housed in the box body.
The series external diagnosis reagent case comprises that tumor markers series diagnosis kit, thyroid function series diagnosis kit, reproductive endocrine hormone series diagnosis kit, infectious disease series diagnosis kit, myocardium mark series diagnosis kit, diabetes series diagnosis kit, cortisol detect diagnostic kit, total IgE detects diagnostic kit.
Constant temperature incubation device is constant temperature oven or water-bath.
Wash panel assembly for washing the plate machine.
Chemiluminescence detecting is selected chemiluminescence detector for use.
Novel enzyme-catalyzed chemiluminescence immune detection system is that chemiluminescence or bioluminescence system are combined with immune response, be used to detect a kind of novel markings immunoassay device of micro-antigen or antibody, compare with radiommunoassay equipment, do not use harmful reagent in the utility model test, avoided the pollution of radioactive nuclide and to operating personnel's injury, shortened detection time greatly, have highly sensitive advantage simultaneously concurrently, easy and simple to handle, be easy to normalizing operation, this equipment can be applicable to biology, medical research and clinical trial diagnostic work.The utility model is used reagent, efficient stable enzyme-catalyzed chemical luminescence substrate system, the complete Chinese management software of independent research, can the detection of realization program, multinomial, the two-point calibration of fast detecting, veneer, print functions such as laboratory test report, Workload Account automatically, have easy to use, advantage such as with low cost is for clinical examination circle provides a cover perfect solution.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
Embodiment
As shown in Figure 1, be placed with serial external diagnosis reagent case 2 on the frame 1 successively, oscillator 3, constant temperature incubation device 4, wash panel assembly 5, chemiluminescence detecting 6 and the control and the analysis management device that cooperate with it, control and analysis management device comprise computing machine 7, display 8, printer 9, keyboard 10, wherein computing machine 7 connects the output terminal of chemiluminescence detecting 6, input end, display 8, printer 9 connects computing machine 7 output terminals respectively, keyboard 10 connects computing machine 7 input ends, series external diagnosis reagent case 2 comprises box body 2-1, immune response microwell plate 2-2 and detectable bottle 2-3 are housed in the box body 2-1, immune response microwell plate 2-2 adopts light tight white 96 AND DEWATERING FOR ORIFICE STRUCTURE of plastics, and serial external diagnosis reagent case 2 comprises tumor markers series diagnosis kit, thyroid function series diagnosis kit, reproductive endocrine hormone series diagnosis kit, infectious disease series diagnosis kit, cardiac muscle mark series diagnosis kit, diabetes series diagnosis kit, cortisol detects diagnostic kit, total IgE detects diagnostic kit; Oscillator 3 is selected the MM-1 microoscillator for use; Constant temperature incubation device 4 is constant temperature oven or water-bath, washes the AW1 that panel assembly 5 selects for use Zhengzhou rich match bioengineering company limited to produce and washes the plate machine, and chemiluminescence detecting 6 is selected the Lucy2 or the Llucy3 type chemiluminescence detector of Austrian Anthos company for use.
Operating process: get bag that the patients serum adds the immune response microwell plate in right amount by in the hole, add the enzyme labeling thing simultaneously, label is the antigen or the antibody of horseradish peroxidase (HRP) mark, put on the small-sized oscillator and shook 1 minute, put interior 37 degree of constant temperature oven incubation down, at this moment react antigen-antibody reaction takes place in the micropore, form immune complex, wash plate machine washing plate with AW1, unnecessary enzyme labeling thing and unreacted reactant are removed, add the good chemical luminous substrate of mixed in equal amounts in advance then, shook 1 minute, put into chemiluminescence detector, substrate system under alkali condition by HRP catalysis, redox reaction takes place, produce photon, by chemical photic device luminous signal is amplified, read the relative light unit in every hole according to the program of computer installation, and transfer data to control computer, computing machine carries out analyzing and processing to data, contrast with typical curve, automatically be converted into the concrete content of corresponding measured object, be presented on the display, can also pass through the printer prints result, control of the present utility model and analysis management device can also be to standard items, quality-control product, the yin and yang attribute contrast, samples etc. carry out free layout according to the test needs, comprehensively quantitative test, can carry out point-to-point, linear regression, cubic spline, four parameters, curve fittings such as logit-log, coordinate axis can be carried out linearity, logarithm, natural logarithm is freely selected, and has the multinomial function of veneer, support that at most nearly 12 are detected simultaneously, also have the qualitative analysis function, support nearly 4 groups of critical value settings, 5 groups of qualitative groupings.The utlity model has rich and varied data output form: the chinesization verification certificate is printed, and various measurement projects are selected arbitrarily, and matrix is printed, whole plate measurement result comes into plain view, various informative statistical function, multiple statistics is freely exported, thereby has alleviated tester's labour intensity greatly.
Claims (7)
1, a kind of novel enzyme-catalyzed chemiluminescence immune detection system, comprise frame, it is characterized in that the control and the analysis management device that be placed with serial external diagnosis reagent case, oscillator, constant temperature incubation device on the frame successively, wash panel assembly, chemiluminescence detecting reach cooperation with it.
2, novel enzyme-catalyzed chemiluminescence immune detection system as claimed in claim 1, it is characterized in that, control and analysis management device comprise computing machine, display, printer, keyboard, wherein computing machine connects output terminal, the input end of chemiluminescence detecting, display, printer connect fanout respectively, and keyboard connects the computing machine input end.
3, novel enzyme-catalyzed chemiluminescence immune detection system as claimed in claim 1 is characterized in that, serial external diagnosis reagent case comprises box body, and immune response microwell plate and detectable bottle are housed in the box body.
4, novel enzyme-catalyzed chemiluminescence immune detection system as claimed in claim 3, it is characterized in that serial external diagnosis reagent case comprises that tumor markers series diagnosis kit, thyroid function series diagnosis kit, reproductive endocrine hormone series diagnosis kit, infectious disease series diagnosis kit, myocardium mark series diagnosis kit, diabetes series diagnosis kit, cortisol detect diagnostic kit, total IgE detects diagnostic kit.
5, novel enzyme-catalyzed chemiluminescence immune detection system as claimed in claim 1 is characterized in that, constant temperature incubation device is constant temperature oven or water-bath.
6, novel enzyme-catalyzed chemiluminescence immune detection system as claimed in claim 1 is characterized in that, washes panel assembly for washing the plate machine.
7, novel enzyme-catalyzed chemiluminescence immune detection system as claimed in claim 1 is characterized in that chemiluminescence detecting is selected chemiluminescence detector for use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620135141 CN200986546Y (en) | 2006-12-21 | 2006-12-21 | Novel enzymatic chemiluminescence immunity detection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620135141 CN200986546Y (en) | 2006-12-21 | 2006-12-21 | Novel enzymatic chemiluminescence immunity detection system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN200986546Y true CN200986546Y (en) | 2007-12-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200620135141 Expired - Lifetime CN200986546Y (en) | 2006-12-21 | 2006-12-21 | Novel enzymatic chemiluminescence immunity detection system |
Country Status (1)
| Country | Link |
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| CN (1) | CN200986546Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101387650B (en) * | 2007-12-20 | 2012-06-27 | 北京科美生物技术有限公司 | Full automatic plate type luminous instrument and luminous detecting method thereof |
| CN103792225A (en) * | 2012-10-29 | 2014-05-14 | 科蒂亚(新乡)生物技术有限公司 | Chemiluminescence analysis instrument |
-
2006
- 2006-12-21 CN CN 200620135141 patent/CN200986546Y/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101387650B (en) * | 2007-12-20 | 2012-06-27 | 北京科美生物技术有限公司 | Full automatic plate type luminous instrument and luminous detecting method thereof |
| CN103792225A (en) * | 2012-10-29 | 2014-05-14 | 科蒂亚(新乡)生物技术有限公司 | Chemiluminescence analysis instrument |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: ZHENGZHOU AUTOBIO ENGINEERING CO., LTD. Free format text: FORMER NAME: ZHENGZHOU AUTOBIO DIAGNOSTICS CO., LTD. |
|
| CP03 | Change of name, title or address |
Address after: 450016 Zhengzhou economic and Technological Development Zone, Henan, North Road, No. 1, No. 87 Patentee after: Autobio Diagnostics Co., Ltd. Address before: 450016, No. fifth, No. 87, No. 1, main street, Zhengzhou economic and Technological Development Zone, Henan Patentee before: Zhengzhou Autobio Diagnostics Co., Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20071205 |
|
| EXPY | Termination of patent right or utility model |