CN206546331U - The fluorescence immunity analyzer of illegal drug in a kind of quick detection food - Google Patents

The fluorescence immunity analyzer of illegal drug in a kind of quick detection food Download PDF

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Publication number
CN206546331U
CN206546331U CN201720095208.5U CN201720095208U CN206546331U CN 206546331 U CN206546331 U CN 206546331U CN 201720095208 U CN201720095208 U CN 201720095208U CN 206546331 U CN206546331 U CN 206546331U
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module
main frame
control module
central processing
processing unit
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CN201720095208.5U
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王莲
唐海波
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Shanghai Taiyu Biotechnology Co ltd
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Beijing Zhongke Huiren Technology Co Ltd
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Abstract

The utility model discloses a kind of fluorescence immunity analyzer of illegal drug in quick detection food, main frame including rectangular configuration, the top surface of the main frame is provided with touch control display, the side of the main frame is provided with PORT COM and power interface, the front of the main frame is provided with test card plug, central processing unit is provided with inside the main frame, the central processing unit includes control module, the control module connects touch-control module respectively, power module and analysis module, the touch-control module connection control touch control display, the analysis module connecting detection unit, the central processing unit connects driver element, the driver element is arranged on the test card spigot.The utility model offer is a kind of can be conveniently using the detecting instrument of fluoroimmunoassay, it detects relative to existing colloidal gold chromatography and ELISA, with small volume, it is lightweight, install that simple, easy to operate, detection speed is fast, sensitivity is high and being capable of quantitative analysis detection.

Description

The fluorescence immunity analyzer of illegal drug in a kind of quick detection food
Technical field
The utility model is related to field of detection of food safety, more particularly to one kind being capable of illegal drug in quick detection food Fluorescence immunity analyzer.
Background technology
Food security is great livelihood issues, relation body health of people and life security, and tie society is harmonious It is stable.But the basis of current China food security is still weaker, food industries have a large capacity and a wide range, and quality is not overall high, raw Produce management and owe specification, some operator's morality, Credit Shortages deliberately produce and process food of poor quality, and addition is each The forbidden drug of formula various kinds, causes food safety affair to happen occasionally.In plantation and production process, have to promote production With the residues of pesticides caused by the chemical fertilizer, agricultural chemicals for suppressing pest and disease damage and adding;Cultivating and processing in transportation, equally having Residue of veterinary drug caused by veterinary drug and hormone for promote growth and suppress disease, controlling death and adding etc. etc.;Moreover, also Have along with industrial development, the dirt at water source, air and soil caused by a large amount of poisonous and hazardous chemicals of discharge, discarded object Dye, and the different kind organism toxin such as the spontaneous aflatoxin of nature, Microcystin.Therefore, from soil and water Heavy metal, clenbuterol hydrochloride and chloramphenicol into meat, melamine and antibiotic in dairy products, the malachite in aquatic products Green and nitrofuran, then aflatoxin and residues of pesticides into cereal etc., it would be desirable to the sample of detection is multifarious, Project reaches hundreds of varieties.
Traditional medicament residue analysis is mainly using gas-chromatography (GC), high performance liquid chromatography (HPLC), spectrum point The physics and chemistry such as analysis, gas chromatography mass spectrometry, LC-MS means carry out qualitative and quantitative analysis.These analysis methods need to carry sample The pretreatment process such as take, purify, concentrating, deriving, operating procedure is complicated, the limitation such as technical threshold height.
Immuno analytical method (IA) is one of retention analysis technology of 1990s priority research development and utilization, should Method is simple, quick, sensitivity height, high specificity, analyze that capacity is big, cost is low.Immuno analytical method is the spy with antigen-antibody Detection technique based on different in nature, reversible sexual reaction, with high specific and the characteristics of high selectivity, is highly suitable for multiple The separation or detection of miscellaneous matrix trace components.Interpenetrated with interdisciplinary, the scope that immunology is related to constantly expands, new Immunological detection method emerges in an endless stream, and its application is also expanding day by day, not only as various clinical disease quick diagnosis Important method, it is convenient also to be provided for food security quick detection research.
More mainly colloidal gold chromatography and the ELISA applied at present.Colloidal gold method is a kind of simple and quick Qualitative checking method, directly by naked eyes result of determination, sensitivity is generally in 1~2ug/kg or so, and its sensitivity does not reach The limitation requirement (0.2~0.5ug/kg) of country, and can not accurate quantitative analysis.The detection sensitivity of ELISA is remote high In colloidal gold method, but its operating process is cumbersome, generally requires multiple sample-adding, washing, to the requirement of operating personnel's professional technique Compare high, easily because operating error causes result inaccurate in detection process.
Fluoroimmunoassay (FIA) has the advantages that high sensitivity, selectivity is strong, need sample amount few and simple and efficient, its The Monitoring lower-cut generally 2-4 order of magnitude higher than AAS.Fluorescence immunity analyzer (FIAT) can be carried out single or many simultaneously The qualitative and quantitative detection of individual analyte, sensitivity is up to ng/ml grades.Therefore lacking a kind of can be applied to food illegal drug Rapid fluorescence detecting instrument.
Utility model content
In order to answer it is food-safe in numerous illegal drugs, medicament residue and biotoxin etc. carry out quick and precisely, The demand quantitatively detected, the purpose of this utility model there is provided it is a kind of can be achieved to the intelligent machine-readable of testing result, it is sensitive The high fluorescence immunity analyzer of degree, and fluorescence immune chromatography technical operation is simple, time-consuming short, need to only be loaded can intelligently read inspection Survey result, test result can field print or preserve call for subsequent query.
The purpose of this utility model is achieved through the following technical solutions:
The fluorescence immunity analyzer of illegal drug in a kind of quick detection food, includes the main frame of rectangular configuration, the master The top surface of machine is provided with touch control display, and the side of the main frame is provided with PORT COM and power interface, the front of the main frame Provided with test card plug, central processing unit is provided with inside the main frame, the central processing unit includes control module, the control Module connects power module and analysis module respectively, and the analysis module connecting detection unit, the central processing unit connection is driven Moving cell, the driver element is arranged on the test card spigot.
Further, the detection unit includes excitation source, fluorescence detector and the photoelectricity of link control module respectively Converter, wherein fluorescence detector linking parsing module.
Further, built-in printer is additionally provided with the main frame, the printer is connected with the central processing unit, Top surface of the printing outlet of the printer positioned at main frame.
Further, the central processing unit also includes memory module, and the memory module connects the control module, its For storing testing result.
Further, the central processing unit also includes induction module, and the induction module connects the control module, institute Induction module is stated for Information reading unit, it is correspondingly arranged at the card-reading zone of the main frame top surface.
Further, the central processing unit also includes mixed-media network modules mixed-media, and the mixed-media network modules mixed-media connects the control module.
Further, the mixed-media network modules mixed-media includes Wifi modules, 3G module, 4G modules, bluetooth module and Zigbee module At least one of.
Further, the control module is PLC or high-speed microprocessor.
Further, the PORT COM includes I/O interfaces and USB interface.
The beneficial effects of the utility model are:Originally it is that utility model provides one kind and can conveniently apply fluoroimmunoassay Detecting instrument, it is detected relative to existing colloidal gold chromatography and ELISA, with small volume, it is lightweight, install Simply, easy to operate, detection speed is fast, sensitivity is high and can quantitative analysis detection, while can also realize online real time print, Storages of a variety of detection data and the characteristics of to testing result online management.
Brief description of the drawings
Fig. 1 is the outer of the fluorescence immunity analyzer of illegal drug in the quick detection food that the utility model embodiment is provided Portion's structure chart;
Fig. 2 is the interior of the fluorescence immunity analyzer of illegal drug in the quick detection food that the utility model embodiment is provided Portion's system block diagram.
In figure:1st, main frame;2nd, touch control display;3rd, PORT COM;4th, power interface;5th, card plug is tested;6th, centre Manage device;7th, control module;8th, touch-control module;9th, power module;10th, analysis module;11st, detection unit;12nd, driver element;13、 Printer;14th, induction module;15th, card-reading zone;16th, memory module;17th, mixed-media network modules mixed-media.
Embodiment
It is new below in conjunction with this practicality to make the purpose, technical scheme and advantage of the utility model embodiment clearer Accompanying drawing in type embodiment, the technical scheme in the utility model embodiment is clearly and completely described, it is clear that retouched The embodiment stated is a part of embodiment of the utility model, rather than whole embodiments.Generally here described in accompanying drawing and The component of the utility model embodiment shown can be arranged and designed with a variety of configurations.Therefore, below to attached The detailed description of the embodiment of the present utility model provided in figure is not intended to limit claimed scope of the present utility model, It is merely representative of selected embodiment of the present utility model, rather than whole embodiments.Based on the embodiment in the utility model, sheet The every other embodiment that field those of ordinary skill is obtained under the premise of creative work is not made, belongs to this practicality Novel protected scope.
As shown in figure 1, Fig. 1 shows that the fluorescence of illegal drug in the quick detection food that utility model embodiment is provided is exempted from Epidemic disease analyzer, includes the main frame 1 of rectangular configuration, and the top surface of main frame 1 is provided with touch control display 2, and the side of main frame 1 is provided with communication Port and power interface 4, the front of main frame 1 is provided with test card plug 5.
As shown in Fig. 2 the inside of main frame 1 is provided with central processing unit 6, central processing unit 6 includes control module 7, control module 7 Power module 9 and analysis module 10 are connected respectively, and the connecting detection unit 11 of analysis module 10, the connection driving of central processing unit 6 is single Member 12, driver element 12 be arranged on it is described test card plug 5 at, driver element 12 be stepper motor, can by detect card from It is dynamic to be moved to the position corresponding to detection unit 11.
Wherein, control module 7 is PLC or high-speed microprocessor, and detection unit 11 includes link control module 7 respectively Excitation source, fluorescence detector and optical-electrical converter, wherein fluorescence detector linking parsing module 10, during work, by exciting Light source emits beam irradiation sample, and the fluorescent nanometer microsphere in sample reflects fluorescence, fluorescence detector is detected by exciting Fluorescence signal, the analysis module 10 that electric signal feeds back to central processing unit 6 is converted to by photovoltaic converter.
As further preferred embodiment, be additionally provided with built-in printer 13 in main frame 1, printer 13 with it is described in Central processor 6 is connected, and the printing outlet of printer 13 is positioned at the top surface of main frame 1, and it can facilitate real time print testing result.
It is preferred that, central processing unit 6 also includes memory module 16, and memory module 16 connects the control module 7, and it is used for Store testing result.
Still more preferably, central processing unit 6 also includes induction module 14, and induction module 14 connects the control mould Block 7, induction module 14 is Information reading unit, and it is correspondingly arranged at the card-reading zone 15 of the top surface of main frame 1, and it is scanned for IC-card Area, its detection project calibration curve equation being stored in by surface sweeping in IC-card is read in the holder of instrument automatically, is used for The calculating of final detection data.
As embodiment still more preferably, central processing unit 6 also includes mixed-media network modules mixed-media 17, and mixed-media network modules mixed-media 17 connects The control module 7 is connect, it mainly realizes that network is docked, and facilitates the online management of user profile and detection information.
Wherein, mixed-media network modules mixed-media 17 is included in Wifi modules, 3G module, 4G modules, bluetooth module and Zigbee module extremely Few one kind.
It is preferred that, PORT COM includes I/O interfaces and USB interface, can connect exterior PC end or external printer 13 Etc. equipment, for carrying out comparing result macroscopic analysis and printing contrast comparing result, or printing different material is made simultaneously Testing result, sets up customer data base.
The fluorescence immunity analyzer that the utility model is provided is applied to immunological technique and fluorescent quantitation, is by fluorescence spectrophotometer light Spend the analysis system that the accurate quantification principle and immunochromatography competitive reaction technology of meter are combined.Will be with fluorescent marker during detection The detection sample fully mixed is added in the well of immunochromatographydetection detection card, process of the analyte in sample in chromatography In form immune complex, the upper coated antigen of detection card can and analyte competition binding fluorescence labeling in sample it is anti- Body.When detection card is inserted into fluorescence immunity analyzer, light source is irradiated to the detection zone and quality control region of detection card, excites attachment Fluorescent material, its fluorescence signal launched is collected is converted into electric signal by optical-electrical converter, electric signal it is strong and weak and glimmering Optical molecule quantity is strictly related, and both are linear, analyzer meeting automatically scanning T areas fluorescence signal intensity, and substitutes into instrument The calibration curve equation obtained from IC-card, it is possible to calculate the content of analyte in sample to be checked.
Concrete operation step of the present utility model is as follows:
Fluorescent material on detection card produces the transmitting of 650nm wavelength after the 590nm exciting lights that instrument is launched shine Light, its intensity for launching light can be measured by instrument precision.And the analysis system stored by instrument, accurately calculate in sample and treat Survey thing content.
1st, power switch device is opened, instrument starts and starts self-inspection.(including detection basic software and hardware capability whether Normally), start shooting normal then into main menu.
2nd, the IC smart cards containing detection project calibration curve equation are put into IC-card scanning area first, by IC smart cards Calibration curve equation read automatically in the holder of instrument.
3rd, in test interface, soft keyboard, typing sample message etc. are used.
4th, sample mixed liquor is added drop-wise in the well of detection card, and be inserted into the detection card plug of instrument, then Click on " starting test ".
5th, fluorescence immunity analyzer can be automatic to calculate containing for detection object in sample according to the calibration curve equation of typing Amount.
6th, obtained result is detected, can directly be printed by built-in printer, or is stored in result queries and is easy to Inquiry, can also realize network connection, to the online management of user profile and detection information by mixed-media network modules mixed-media later.
Fluorescence immunity analyzer of the present utility model, detection range is wide, it is adaptable to field of detection of food safety it is exhausted mostly The quick detection of number forbidden drug, animal epidemic and mycotoxin, it is possible to achieve the calibration that instrument obtains same batch automatically is bent Line, the automatically delivering of fluorescent chromatographic detection card, the detection of fluorescence reaction, fluorescence signal is automatically analyzed, the printing of testing result, The functions such as the networking of testing result, and detection sensitivity and the degree of accuracy are high, and control accuracy is good, simple to operate.
Finally it should be noted that:Above-described each embodiment is merely to illustrate the technical solution of the utility model, rather than It is limited;Although the utility model is described in detail with reference to the foregoing embodiments, one of ordinary skill in the art It should be understood that:It can still modify to the technical scheme described in previous embodiment, or to which part or whole Technical characteristic carries out equivalent substitution;And these modifications or substitutions, the essence of appropriate technical solution is departed from the utility model The scope of each embodiment technical scheme.

Claims (9)

1. the fluorescence immunity analyzer of illegal drug, includes the main frame of rectangular configuration in a kind of quick detection food, its feature exists In:The top surface of the main frame is provided with touch control display, and the side of the main frame is provided with PORT COM and power interface, the master The front of machine is provided with central processing unit provided with test card plug, the main frame inside, and the central processing unit includes control module, The control module connects touch-control module, power module and analysis module, the touch-control module connection control touch-control respectively Display, the analysis module connecting detection unit, the central processing unit connects driver element, and the driver element is arranged on The test card spigot.
2. the fluorescence immunity analyzer of illegal drug in quick detection food as claimed in claim 1, it is characterised in that:It is described Detection unit includes excitation source, fluorescence detector and the optical-electrical converter of link control module respectively, wherein fluorescence detector Linking parsing module.
3. the fluorescence immunity analyzer of illegal drug in quick detection food as claimed in claim 1, it is characterised in that:It is described Built-in printer is additionally provided with main frame, the printer is connected with the central processing unit, the printing outlet of the printer Positioned at the top surface of main frame.
4. the fluorescence immunity analyzer of illegal drug in quick detection food as claimed in claim 1, it is characterised in that:It is described Central processing unit also includes memory module, and the memory module connects the control module, and it is used to store testing result.
5. the fluorescence immunity analyzer of illegal drug in quick detection food as claimed in claim 4, it is characterised in that:It is described Central processing unit also includes induction module, and the induction module connects the control module, and the induction module reads for information Unit, it is correspondingly arranged at the card-reading zone of the main frame top surface.
6. the fluorescence immunity analyzer of illegal drug in quick detection food as claimed in claim 5, it is characterised in that:It is described Central processing unit also includes mixed-media network modules mixed-media, and the mixed-media network modules mixed-media connects the control module.
7. the fluorescence immunity analyzer of illegal drug in quick detection food as claimed in claim 6, it is characterised in that:It is described Mixed-media network modules mixed-media includes at least one of Wifi modules, 3G module, 4G modules, bluetooth module and Zigbee module.
8. the fluorescence immunity analyzer of illegal drug in the quick detection food as described in claim 1 or 4, it is characterised in that: The control module is PLC or high-speed microprocessor.
9. the fluorescence immunity analyzer of illegal drug in quick detection food as claimed in claim 1, it is characterised in that:It is described PORT COM includes I/O interfaces and USB interface.
CN201720095208.5U 2017-01-24 2017-01-24 The fluorescence immunity analyzer of illegal drug in a kind of quick detection food Expired - Fee Related CN206546331U (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109061093A (en) * 2018-10-08 2018-12-21 四川众望安全环保技术咨询有限公司 A kind of Portable water quality monitoring device
CN110333212A (en) * 2019-08-13 2019-10-15 江苏省苏微微生物研究有限公司 A kind of time-resolved fluorescence immunoassay instrument and its application with multi-channel detection function
CN110389120A (en) * 2019-07-22 2019-10-29 云霄县食品快检中心 A kind of detection data method for uploading based on fast inspection vehicle
CN111497461A (en) * 2020-05-26 2020-08-07 广东星创众谱仪器有限公司 Intelligent machine for edible agricultural product qualification certificate and working method thereof
CN113295664A (en) * 2021-05-24 2021-08-24 南京火眼金睛安全科技有限公司 Domestic sewage component detection method, device and system
CN114324783A (en) * 2021-12-30 2022-04-12 辽宁华一检测认证中心有限公司 Fluorescence immunoassay appearance of contraband medicine in short-term test food

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109061093A (en) * 2018-10-08 2018-12-21 四川众望安全环保技术咨询有限公司 A kind of Portable water quality monitoring device
CN110389120A (en) * 2019-07-22 2019-10-29 云霄县食品快检中心 A kind of detection data method for uploading based on fast inspection vehicle
CN110333212A (en) * 2019-08-13 2019-10-15 江苏省苏微微生物研究有限公司 A kind of time-resolved fluorescence immunoassay instrument and its application with multi-channel detection function
CN111497461A (en) * 2020-05-26 2020-08-07 广东星创众谱仪器有限公司 Intelligent machine for edible agricultural product qualification certificate and working method thereof
CN113295664A (en) * 2021-05-24 2021-08-24 南京火眼金睛安全科技有限公司 Domestic sewage component detection method, device and system
CN114324783A (en) * 2021-12-30 2022-04-12 辽宁华一检测认证中心有限公司 Fluorescence immunoassay appearance of contraband medicine in short-term test food

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Effective date of registration: 20200507

Address after: 200431 room 3094, building 3, No. 201, Aihui Road, Baoshan District, Shanghai

Patentee after: Shanghai Taiyu Biotechnology Co.,Ltd.

Address before: 100091 Beijing city Haidian District yellow car No. 2 Building 2 room X06-668

Patentee before: BEIJING ZHONGKE HUI REN SCIENCE AND TECHNOLOGY Co.,Ltd.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20171010

Termination date: 20220124