CN203164187U - Gold label detector for colloidal gold - Google Patents
Gold label detector for colloidal gold Download PDFInfo
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- CN203164187U CN203164187U CN 201320030224 CN201320030224U CN203164187U CN 203164187 U CN203164187 U CN 203164187U CN 201320030224 CN201320030224 CN 201320030224 CN 201320030224 U CN201320030224 U CN 201320030224U CN 203164187 U CN203164187 U CN 203164187U
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Abstract
The utility model discloses a gold label detector for colloidal gold. The detector comprises an image collecting system for collecting images of a test strip, a central control system for analyzing and processing the collected images and a printing device for printing the analyzed and processed result. The image collecting system and the printing device are connected to the central control system and are interactive in information. The utility model provides the gold label detector for colloidal gold to detect information of the test strip qualitatively and quantitively and record the analyzing data result which can be printed and output.
Description
Technical field
The utility model relates to a kind of automatic detection device of Biosample, especially a kind of collaurum gold mark detector, the qualitative and quantitative analysis that can be correlated with to the test strips of being made by collaurum (melamine, Clenbuterol etc.).
Background technology
The colloidal gold strip baffled photometer is called for short collaurum gold mark detector, quick and precisely quantitative test colloidal gold immuno-chromatography test paper strip.According to the characteristic of colloid gold particle between the 10-100nm to the peak absorbance of light, by visible light or laser scanning, measure the reflection case on the colloidal gold strip, by micro computer the integration that detects band and quality control band is compared, calculate the quantity of colloid gold particle on the relative quality control band of colloid gold particle of immune combination, calculated by the concentration of check reagent by formula again.And then realize that the detection of dynamic of colloidal gold immunochromatographimethod reaction is had good response characteristic in big concentration range.
(colloidal gold immunochromatography assay GICA) is a kind of solid phase labelling immunoassay technology that multiple technologies such as colloidal gold-labeled method, immunoassay technology and chromatographic analysis technology are organically combined to the colloidal gold immunochromatographimethod technology.Easy and simple to handle, quick because of it, and has very high specificity and susceptibility, in the clinical medicine check, obtain development quickly, be widely used in the clinical detection as diseases such as human chorionic gonadotrophin, the plague, hepatitis B, parasite, myocardial damage, acquired immune deficiency syndrome (AIDS) at present.
Collaurum can show numerous characteristics, particularly absorption Spectrum characteristic when size is reduced to nanometer scale, have important use in fields such as materialogy, clinical medicine, life sciences and be worth.To studies show that of colloid gold particle absorption Spectrum characteristic, when the nanogold particle particle diameter was between 10-100nm, its absorption peak was between 510-550nm; Along with the increase of nanogold particle particle diameter, its absorption peak moves east to ruddiness, and is the linear changing relation basically between absorption peak wavelength and the particle diameter, so a large amount of nanogold particle is shown as kermesinus when assembling.
Collaurum is the aqueous solution of gold chloride, and it aggregates into the colloid gold particle of specific size (3nm-80nm) under the effect of reductive agent, and owing to electrostatic interaction forms a kind of stable colloidal state.Colloid gold label comes down to macromolecules such as protein molecule and is adsorbed to the bag on colloid gold particle surface by process, adsorption mechanism is colloid gold particle electronegative character under alkali condition, lean on electrostatic interaction and strong bonded with the positive charge group of protein molecule, thereby have good stable.The immunochromatographiassays assays method that with the collaurum is label has been widely used in fields such as histopathology and immunology diagnosis.
Although the colloidal gold immunochromatographimethod technology has a wide range of applications in clinical medicine check field, at present only with ocular estimate to dripping having or not of on gold-marking immunity test strips checking matter and do qualitative or sxemiquantitative being judged.Have following shortcoming: 1) measurement result is subject to the interference of human factor, and objectivity is poor; 2) can not monitoring bio the dynamic process of reaction.3) inaccurate.
The utility model content
At existing ocular estimate to be subject in the prior art to think factor to disturb the not high problem of accuracy, the utility model provides a kind of collaurum gold mark detector, test strip information that can be qualitative, quantitative, and record analysis data result, printable output.
To achieve these goals, a kind of collaurum gold of the utility model mark detector, described collaurum gold mark detector comprises for the image capturing system that test strips is carried out image acquisition, the image of gathering is carried out the central control system of analyzing and processing and the printing equipment that the result of analyzing and processing is printed, described image capturing system and printing equipment all are connected on the described central control system, interactive information.
Further, described central control system connects the multiplex image acquisition system simultaneously, and the described image capturing system of multichannel can send to central control system simultaneously with image information.
Further, described image capturing system comprises camera and lamp plate, and described camera is connected with described central control system, and described lamp plate provides light source when the camera collection image.
Further, described central control system is carried out analyzing and processing by the image information of OpenCV, draws T/C line ratio, and then draws corresponding reagent concentration.
Further, also be connected with the display screen for man-machine interaction on the described collaurum gold mark detector, described display screen is connected with described central control system.
Further, described central control system is provided with the USB expansion board that can be connected with external input device, and described multiplex image acquisition system is connected with central control system by the USB expansion board.
The utility model provides a kind of collaurum gold mark detector, and the setting of multiplex image acquisition system can detect a plurality of test paper information simultaneously, is conducive to the big data quantity analysis, has improved detection efficiency; The USB expansion board can be connected with external input device, can realize communications such as information typing, utilizes central control system that test paper information is carried out analyzing and processing; Utilize printing device that result is recorded on the paper, be convenient to read and preserve; Display screen is convenient to man-machine interaction.
Description of drawings
Fig. 1 is the structural representation of the utility model collaurum gold mark detector.
Embodiment
Below in conjunction with accompanying drawing, embodiment of the present utility model is elaborated.
Be illustrated in figure 1 as the specific embodiment of collaurum gold mark detector of the present utility model, central control system comprises central authorities' control mainboard, central processing unit on the mainboard adopts the EPIA-P820 series control processor of VIA Technologies, this mainboard adopts the x86 framework, can perfect integration windows operating system, so just simplified the design cycle of software program greatly, while this processor adopting Pico-ITX standard, size has only 10cm
7.2cm, can perfectly realize handheld operation.2G DDR3 internal storage and 4G Flash have been installed as program storage on the mainboard, central control system is carried out analyzing and processing by the image information of OpenCV, draws T/C line ratio, and then draws corresponding reagent concentration.。6.4 cun technical grade LCD are adopted in the output of processor, are connected with processor by the LVDS interface, realize that resolution is 640
The screen of 480 pixels shows output.And the input of processor adopts one to realize with the touch-screen that covers on the display screen, this touch-screen by a drive circuit board after, be connected with master controller employing USB interface.Adopt camera in addition and the lamp plate for the camera power supply of USB interface simultaneously, camera and lamp plate constitute the image capturing system of test paper information, and lamp plate adopts the 5V of USB output to power.Also 8 channel image acquisition systems have been expanded by the USB expansion board in addition, also can be connected with other USB input equipments, this module can realize that 8 passages of collaurum detect simultaneously, also can realize some common input/output functions by this USB interface, for example be equipped with wireless wifi module, radio keyboard mouse or insertion USB flash disk etc.By the RS232 interface of mainboard, connected a mini-printer, adopt the ZY-TP12 series printer of Zhou Ligong company, can realize that collaurum detects the output of information, so that keep and reading.The whole control system adopts a block power supply adapter and DC-DC module to realize power supply, and output has 12V direct current and two standards of 5V direct current, and the 12V power supply is control panel, monitor power supply, and the 5V power supply is display, printer power supply.Adopt this Control System Design, can realize the software design easily, simultaneity factor can have one and the similar function of PC.
Above-mentioned example just is used for explanation the utility model, and embodiment of the present utility model is not limited to these examples, and the various embodiments that meet the utility model thought that those skilled in the art make are all within protection domain of the present utility model.
Claims (6)
1. a collaurum gold is marked detector, it is characterized in that, described collaurum gold mark detector comprises for the image capturing system that test strips is carried out image acquisition, the image of gathering is carried out the central control system of analyzing and processing and the printing equipment that the result of analyzing and processing is printed, described image capturing system and printing equipment all are connected on the described central control system, interactive information.
2. a kind of collaurum gold mark detector as claimed in claim 1 is characterized in that described central control system connects the multiplex image acquisition system simultaneously, and the described image capturing system of multichannel can send to central control system simultaneously with image information.
3. a kind of collaurum gold mark detector as claimed in claim 2 is characterized in that described image capturing system comprises camera and lamp plate, and described camera is connected with described central control system, and described lamp plate provides light source when the camera collection image.
4. a kind of collaurum gold mark detector as claimed in claim 3 is characterized in that described central control system is carried out analyzing and processing by the image information of OpenCV, draws T/C line ratio, and then draws corresponding reagent concentration.
5. a kind of collaurum gold mark detector as claimed in claim 4 is characterized in that, also is connected with the display screen for man-machine interaction on the described collaurum gold mark detector, and described display screen is connected with described central control system.
6. a kind of collaurum gold as claimed in claim 5 is marked detector, it is characterized in that, described central control system is provided with the USB expansion board that can be connected with external input device, and described multiplex image acquisition system is connected with central control system by the USB expansion board.
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CN 201320030224 CN203164187U (en) | 2013-01-21 | 2013-01-21 | Gold label detector for colloidal gold |
Applications Claiming Priority (1)
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CN 201320030224 CN203164187U (en) | 2013-01-21 | 2013-01-21 | Gold label detector for colloidal gold |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103076449A (en) * | 2013-01-21 | 2013-05-01 | 中国检验检疫科学研究院 | Colloidal gold label detector |
CN103439486A (en) * | 2013-09-05 | 2013-12-11 | 凌中鑫 | PCT (Paper of Colloidal Test) chromatographic detector |
CN107219225A (en) * | 2017-05-26 | 2017-09-29 | 无锡中德伯尔生物技术有限公司 | A kind of multichannel collaurum reads instrument and its detection method |
-
2013
- 2013-01-21 CN CN 201320030224 patent/CN203164187U/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103076449A (en) * | 2013-01-21 | 2013-05-01 | 中国检验检疫科学研究院 | Colloidal gold label detector |
CN103439486A (en) * | 2013-09-05 | 2013-12-11 | 凌中鑫 | PCT (Paper of Colloidal Test) chromatographic detector |
CN107219225A (en) * | 2017-05-26 | 2017-09-29 | 无锡中德伯尔生物技术有限公司 | A kind of multichannel collaurum reads instrument and its detection method |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130828 Termination date: 20150121 |
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EXPY | Termination of patent right or utility model |