CN202614770U - Ferritin quantitative detection system - Google Patents
Ferritin quantitative detection system Download PDFInfo
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- CN202614770U CN202614770U CN 201220232552 CN201220232552U CN202614770U CN 202614770 U CN202614770 U CN 202614770U CN 201220232552 CN201220232552 CN 201220232552 CN 201220232552 U CN201220232552 U CN 201220232552U CN 202614770 U CN202614770 U CN 202614770U
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Abstract
The utility model provides a ferritin quantitative detection system, which comprises ferritin detection test paper and a ferritin content analysis and processing device, wherein the ferritin detection test paper comprises a sample pad, a colloidal gold pad, a nitrocellulose film, water absorption filter paper and a reaction support material, the sample pad, the colloidal gold pad, the nitrocellulose film and the water absorption filter paper are sequentially arranged on the reaction support material from one end to the other end, the ferritin content analysis and processing device comprises a central processing module, a power supplying power supply module and a card reading device, the card reading device is used for reading the image information of the ferritin detection test paper, the central processing module is electrically connected with the card reading device, and the power supplying power supply module is respectively and electrically connected with the central processing module and the card reading device. The ferritin quantitative detection system has the advantages that the detection speed is high, the detection program is simple and convenient, and the detection results are reliable.
Description
Technical field
The utility model belongs to the immunology detection field, is specifically related to a kind of ferritin detection by quantitative system.
Background technology
Ferritin is a kind of solvable histone of storing iron in the body, contains small amounts of iron albumen in the normal human serum, generally speaking, and the about 80-130ug/L of male sex's normal mean value, i.e. 80-130ng/ml; And the about 35-55ug/L of women's normal mean value, i.e. 35-55ng/ml.Ferritin is a kind of brown ferritin that contains, and iron-holder is 23%, and the about 750kDa of molecular weight, diameter are 12～14nm.Ferritin mainly contains two kinds of effects in vivo: the first, be used for the synthetic of haemoglobin as the storage vault of iron in the body; The second, iron is kept in the globular protein of hollow, prevent that endocellular liberation iron from too much producing illeffects.Ferritin content can be used as the important references index of liver diseases in the human serum, for judging that the state of an illness has important realistic meaning with understanding to prevent to wait.
At present, the main detection method of ferritin content comprises radioimmunology, ELISA and chemoluminescence method etc. in the serum.But above-mentioned these detection methods all need rely on the instrument and equipment of corresponding complicacy, but also need to use liquid reagent, defective such as therefore, have the trace routine complicacy, detection speed is slow and testing result is unreliable.
The utility model content
To the defective that prior art exists, the utility model provides a kind of ferritin detection by quantitative system, has that detection speed is fast, trace routine is easy and the reliable advantage of testing result.
The technical scheme of the utility model is following:
The utility model provides a kind of ferritin detection by quantitative system, comprising: ferritin detects test paper and ferritin content analysis treating apparatus; Wherein, said ferritin detection test paper comprises: sample pad, collaurum pad, nitrocellulose filter, absorbent filter and reaction holder; Set gradually said sample pad, said collaurum pad, said nitrocellulose filter and said absorbent filter from the end to end of said reaction holder; Said ferritin content analysis treating apparatus comprises: central processing module, power supply module and being used to reads the reader device that said ferritin detects the image information of test paper; Said central processing module is electrically connected with said reader device, and said power supply module is electrically connected with said central processing module and said reader device respectively.
Preferably, the overlapping setting of an end of an end of said sample pad and said collaurum pad, the overlapping setting of an end of the other end of said collaurum pad and said nitrocellulose filter, the overlapping setting of an end of the other end of said nitrocellulose filter and said absorbent filter.
Preferably; The overlapping top that is arranged on an end of said collaurum pad of one end of said sample pad; The overlapping top that is arranged on an end of said nitrocellulose filter of the other end of said collaurum pad, the overlapping below that is arranged on an end of said absorbent filter of the other end of said nitrocellulose filter.
Preferably, said collaurum pad is the collaurum pad that includes the ferritin monoclonal antibody of colloid gold label; Said nitrocellulose filter is arranged with test strip and Quality Control band in parallel; Said test strip includes the ferritin monoclonal antibody and is arranged on the side near said collaurum pad, and said Quality Control band includes the sheep anti-mouse igg polyclonal antibody and is arranged on the side away from said collaurum pad.
Preferably, distance is the 4-8 millimeter between said test strip and the said Quality Control band.
Preferably, the distance between said test strip and the said Quality Control band is 6 millimeters.
Preferably, said reader device is a photoelectric sensor.
Preferably, said reader device is provided with and is used to place the Card Reader mouth that said ferritin detects test paper.
Preferably, said ferritin content analysis treating apparatus also comprises: memory module and/or printer and/or touch operation screen; Said memory module is electrically connected with said central processing module and said power supply module respectively; Said printer is electrically connected with said central processing module and said power supply module respectively, and said touch operation screen is electrically connected with said central processing module and said power supply module respectively.
Preferably, said memory module is a flash memory; Said central processing module is FPGA process chip or DSP process chip.
The beneficial effect of the utility model is following:
Ferritin detection by quantitative provided by the invention system; Through computer image processing technology the testing result that ferritin detects test paper is analyzed; Thereby obtain the ferritin content information in the test sample, minimum to environment or operating personnel's dependence, and simplified the testing process of ferritin; Improve the testing result accuracy of ferritin, also had the advantage that simple, convenient, sense cycle is short, be easy to interpretation.
Description of drawings
The ferritin that Fig. 1 provides for the utility model detects the structural representation of test paper;
The principle schematic of the ferritin content analysis treating apparatus that Fig. 2 provides for the utility model;
The schematic appearance of the ferritin content analysis treating apparatus that Fig. 3 provides for the utility model;
One of the ferritin content analysis treating apparatus that Fig. 4 provides for the utility model is detected the interface;
Another of the ferritin content analysis treating apparatus that Fig. 5 provides for the utility model detects interface;
Wherein, 1-sample pad; 2-collaurum pad; The 3-nitrocellulose filter; The 4-absorbent filter; The 5-printer; 6-touch operation screen; 7-Card Reader mouth; The power switch of 8-power supply module.
Embodiment
Below in conjunction with accompanying drawing the utility model is elaborated:
The utility model embodiment provides a kind of ferritin detection by quantitative system, comprising: ferritin detects test paper and ferritin content analysis treating apparatus; Wherein, ferritin content analysis treating apparatus is used to gather the image information that ferritin detects test paper, and the image information of utilizing the Computer Image Processing analytical to collect, thereby draws the ferritin content in the seized blood.Introduce the structural principle that ferritin detects test paper and ferritin content analysis treating apparatus below respectively:
(1) ferritin detects test paper
As shown in Figure 1, ferritin detects test paper and comprises: sample pad, collaurum pad, nitrocellulose filter, absorbent filter and reaction holder; Set gradually said sample pad, said collaurum pad, said nitrocellulose filter and said absorbent filter from the end to end of said reaction holder.Wherein, the overlapping setting of an end of an end of said sample pad and said collaurum pad, the overlapping setting of an end of the other end of said collaurum pad and said nitrocellulose filter, the overlapping setting of an end of the other end of said nitrocellulose filter and said absorbent filter.Concrete overlap mode is: the overlapping top that is arranged on an end of said collaurum pad of an end of sample pad; The overlapping top that is arranged on an end of said nitrocellulose filter of the other end of said collaurum pad, the overlapping below that is arranged on an end of said absorbent filter of the other end of said nitrocellulose filter.The collaurum pad is the collaurum pad that includes the ferritin monoclonal antibody of colloid gold label; Said nitrocellulose filter is arranged with test strip and Quality Control band in parallel; Said test strip includes the ferritin monoclonal antibody and is arranged on the side near said collaurum pad, and said Quality Control band includes the sheep anti-mouse igg polyclonal antibody and is arranged on the side away from said collaurum pad.Wherein, distance is the 4-8 millimeter between test strip and the Quality Control band, is preferably 6 millimeters.Among Fig. 1, T represents test strip, and C represents the Quality Control band, and arrow is the chromatography direction.
(2) ferritin content analysis treating apparatus
Ferritin content analysis treating apparatus comprises: central processing module, power supply module and being used to reads the reader device that said ferritin detects the image information of test paper; Said central processing module is electrically connected with said reader device, and said power supply module is electrically connected with said central processing module and said reader device respectively.Wherein, reader device is provided with and is used to place the Card Reader mouth that said ferritin detects test paper.Reader device can be photoelectric sensor, is used to gather the image that ferritin detects test paper.For easy to use, said ferritin content analysis treating apparatus also comprises: memory module and/or printer and/or touch operation screen; Said memory module is electrically connected with said central processing module and said power supply module respectively; Said printer is electrically connected with said central processing module and said power supply module respectively, and said touch operation screen is electrically connected with said central processing module and said power supply module respectively.Wherein, memory module can be flash memory (Flash memory); Central processing module can be FPGA process chip or DSP process chip.
The principle of work of the ferritin detection by quantitative system that the utility model provides is:
(1) blood sample to be detected is dropped to the sample pad surface and drips dilution; Wherein, blood sample to be detected can be serum, blood plasma or whole blood etc.;
(2) blood sample to be detected moves to the absorbent filter direction along each attachment of reaction holder; Pick up counting from the moment that blood sample to be detected is dropped to sample pad; Through after the set time; Ferritin is detected the Card Reader mouth that test paper is put into ferritin content analysis treating apparatus, open the power supply module, ferritin content analysis treating apparatus is started working.
In the utility model,, then through the collaurum pad time, can combine to form compound with the ferritin monoclonal antibody specificity of colloid gold label if contain ferritin in the blood sample to be detected; Up along the continuation of reaction holder, through nitrocellulose filter the time, can combine with the ferritin monoclonal antibody specificity that test strip encapsulates, in test strip T place's exhibit red or pink; And at test strip T place colored intensity is relevant with ferritin content in the seized blood sample.Ferritin concentration in the seized blood sample can linear orientation the interval be 0～300ng/ml.
If conform in the blood sample to be detected ferritin is not arranged, then can not form above-mentioned compound, corresponding, can exhibit red or pink at test strip T place;
In addition; No matter whether contain ferritin in the blood sample to be detected; The ferritin monoclonal antibody of colloid gold label all can be up to Quality Control band C place; Combine to form compound with the sheep anti-mouse igg polyclonal antibody specificity that the Quality Control band encapsulates, thereby in Quality Control band C place's exhibit red or pink.Therefore, if Quality Control band C place not exhibit red or pink show that then collaurum lost efficacy or operates wrongly, laboratory test results is invalid, need carry out again.
Therefore, through analyzing and testing band T place and Quality Control band C place colored intensity, can obtain the ferritin content information in the blood sample to be detected.
Wherein, the concrete course of work of ferritin content analysis treating apparatus is:
(21) reader device is gathered the image information that ferritin detects test paper, and the image information that collects is sent to central processing module;
(22) after the next image information of central processing module reading card device transmission is carried out pre-service; Analyze pretreated image information through the typical curve of pre-stored; Obtain the ferritin content information in the seized blood; Store ferritin content information through memory module then, or pass through printer prints ferritin content information, or show ferritin content information through the touch operation screen.
Concrete; The operational process of ferritin content analysis treating apparatus is: after ferritin content analysis treating apparatus powered on, the at first self check of ferritin content analysis treating apparatus was after self check finishes; At touch operation screen displayed map 4 operation interfaces; Select " pattern detection " option, get into Fig. 5 operation interface, at first adjust detected parameters according to tester's needs; Add the time from sample drop and pick up counting when ferritin detects test paper, after reaching the preset set time, ferritin is detected test paper put into the Card Reader mouth, click " " detecting beginning " option of Fig. 5.”
After ferritin content analysis treating apparatus begins to detect; " detecting beginning " among Fig. 5 becomes " in the detection " printed words; After waiting to drip a sound, " graphical display area " locates to show that the ferritin that reads detects the figure of test paper among Fig. 5, and indicates the position that ferritin detects test strip and Quality Control band in the test paper; Simultaneously locate to show delegation's testing result in " data processed result viewing area "; Whether the prompting testing result is effective, if testing result is effective, calculates ferritin content detection value according to built-in in advance typical curve.
In sum; Ferritin detection by quantitative provided by the invention system analyzes the testing result that ferritin detects test paper through computer image processing technology, thereby obtains the ferritin content information in the test sample; Minimum to environment or operating personnel's dependence; And simplified the testing process of ferritin, improved the testing result accuracy of ferritin, also have simple, convenient, sense cycle short, be easy to the advantage of interpretation.
The above only is the preferred implementation of the utility model; Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the utility model principle; Can also make some improvement and retouching, these improvement and retouching also should be looked the protection domain of the utility model.
Claims (10)
1. a ferritin detection by quantitative system is characterized in that, comprising: ferritin detects test paper and ferritin content analysis treating apparatus; Wherein, said ferritin detection test paper comprises: sample pad, collaurum pad, nitrocellulose filter, absorbent filter and reaction holder; Set gradually said sample pad, said collaurum pad, said nitrocellulose filter and said absorbent filter from the end to end of said reaction holder; Said ferritin content analysis treating apparatus comprises: central processing module, power supply module and being used to reads the reader device that said ferritin detects the image information of test paper; Said central processing module is electrically connected with said reader device, and said power supply module is electrically connected with said central processing module and said reader device respectively.
2. ferritin detection by quantitative according to claim 1 system; It is characterized in that; The overlapping setting of one end of one end of said sample pad and said collaurum pad; The overlapping setting of one end of the other end of said collaurum pad and said nitrocellulose filter, the overlapping setting of an end of the other end of said nitrocellulose filter and said absorbent filter.
3. ferritin detection by quantitative according to claim 2 system; It is characterized in that; The overlapping top that is arranged on an end of said collaurum pad of one end of said sample pad; The overlapping top that is arranged on an end of said nitrocellulose filter of the other end of said collaurum pad, the overlapping below that is arranged on an end of said absorbent filter of the other end of said nitrocellulose filter.
4. ferritin detection by quantitative according to claim 1 system is characterized in that said collaurum pad is the collaurum pad that includes the ferritin monoclonal antibody of colloid gold label; Said nitrocellulose filter is arranged with test strip and Quality Control band in parallel; Said test strip includes the ferritin monoclonal antibody and is arranged on the side near said collaurum pad, and said Quality Control band includes the sheep anti-mouse igg polyclonal antibody and is arranged on the side away from said collaurum pad.
5. ferritin detection by quantitative according to claim 1 system is characterized in that, distance is the 4-8 millimeter between said test strip and the said Quality Control band.
6. ferritin detection by quantitative according to claim 5 system is characterized in that the distance between said test strip and the said Quality Control band is 6 millimeters.
7. ferritin detection by quantitative according to claim 1 system is characterized in that said reader device is a photoelectric sensor.
8. ferritin detection by quantitative according to claim 1 system is characterized in that, said reader device is provided with and is used to place the Card Reader mouth that said ferritin detects test paper.
9. ferritin detection by quantitative according to claim 1 system is characterized in that said ferritin content analysis treating apparatus also comprises: memory module and/or printer and/or touch operation screen; Said memory module is electrically connected with said central processing module and said power supply module respectively; Said printer is electrically connected with said central processing module and said power supply module respectively, and said touch operation screen is electrically connected with said central processing module and said power supply module respectively.
10. ferritin detection by quantitative according to claim 9 system is characterized in that said memory module is a flash memory; Said central processing module is FPGA process chip or DSP process chip.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220232552 CN202614770U (en) | 2012-05-22 | 2012-05-22 | Ferritin quantitative detection system |
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| CN 201220232552 CN202614770U (en) | 2012-05-22 | 2012-05-22 | Ferritin quantitative detection system |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103267843A (en) * | 2013-06-08 | 2013-08-28 | 张沈平 | Colloidal gold test paper as well as corresponding colloidal gold analyzer and testing method |
| CN104062425A (en) * | 2013-03-18 | 2014-09-24 | 北京易斯威特生物医学科技有限公司 | Immunochromatography analysis detection system and method |
| CN107436359A (en) * | 2017-07-25 | 2017-12-05 | 江斌 | Ferritin diagnostic kit |
-
2012
- 2012-05-22 CN CN 201220232552 patent/CN202614770U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104062425A (en) * | 2013-03-18 | 2014-09-24 | 北京易斯威特生物医学科技有限公司 | Immunochromatography analysis detection system and method |
| CN104062425B (en) * | 2013-03-18 | 2016-06-29 | 北京易斯威特生物科技股份有限公司 | Immunochromatographiassays assays detection system and method |
| CN103267843A (en) * | 2013-06-08 | 2013-08-28 | 张沈平 | Colloidal gold test paper as well as corresponding colloidal gold analyzer and testing method |
| CN103267843B (en) * | 2013-06-08 | 2015-11-18 | 张沈平 | Colloidal gold test paper card, corresponding collaurum analyser and method of testing |
| CN107436359A (en) * | 2017-07-25 | 2017-12-05 | 江斌 | Ferritin diagnostic kit |
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Granted publication date: 20121219 Termination date: 20130522 |