CN202210101U - Intelligent multifunctional immunity chromatography analysis instrument - Google Patents
Intelligent multifunctional immunity chromatography analysis instrument Download PDFInfo
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- CN202210101U CN202210101U CN2011201604301U CN201120160430U CN202210101U CN 202210101 U CN202210101 U CN 202210101U CN 2011201604301 U CN2011201604301 U CN 2011201604301U CN 201120160430 U CN201120160430 U CN 201120160430U CN 202210101 U CN202210101 U CN 202210101U
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- 238000004587 chromatography analysis Methods 0.000 title claims abstract description 12
- 230000036039 immunity Effects 0.000 title abstract description 7
- 238000000034 method Methods 0.000 claims abstract description 40
- 230000005693 optoelectronics Effects 0.000 claims abstract description 15
- 238000012545 processing Methods 0.000 claims abstract description 8
- 238000004891 communication Methods 0.000 claims abstract description 4
- 238000012360 testing method Methods 0.000 claims description 36
- 238000003556 assay Methods 0.000 claims description 18
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 11
- 239000010931 gold Substances 0.000 claims description 11
- 229910052737 gold Inorganic materials 0.000 claims description 11
- 238000003317 immunochromatography Methods 0.000 claims description 11
- 239000004973 liquid crystal related substance Substances 0.000 claims description 10
- 238000012113 quantitative test Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 3
- 230000003287 optical effect Effects 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 15
- 230000005540 biological transmission Effects 0.000 abstract description 3
- 238000004445 quantitative analysis Methods 0.000 abstract 2
- 230000005622 photoelectricity Effects 0.000 abstract 1
- 238000005070 sampling Methods 0.000 abstract 1
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- 238000003745 diagnosis Methods 0.000 description 6
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- 229920000877 Melamine resin Polymers 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- JDSHMPZPIAZGSV-UHFFFAOYSA-N melamine Chemical compound NC1=NC(N)=NC(N)=N1 JDSHMPZPIAZGSV-UHFFFAOYSA-N 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 238000003127 radioimmunoassay Methods 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
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- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229960004407 chorionic gonadotrophin Drugs 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- 208000016361 genetic disease Diseases 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
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- 238000012549 training Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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Abstract
The utility model provides an intelligent multifunctional immunity chromatography analysis instrument consisting of an optoelectronic scanning process system, a main circuit part and other function systems, wherein the optoelectronic scanning process system is used for executing the acquisition of immunity chromatography quantitative analysis signals; the main circuit part is used for executing the processes of power supply, communication with the exterior, photoelectricity signal processing, instruction transmission, and the like; and the other function systems are used for executing the processes of reading information and standard curves of detected objects, and outputting an operation interface and results. The intelligent multifunctional immunity chromatography analysis instrument is applicable to clinical immunity chromatography quantitative analysis, shortens time to be 10 minutes by transmitting sampling and detecting results to a patient in a packet radio way, avoids the process that the patient waits for getting the detection result in site, and is also applicable to rapid detection on food safety.
Description
Technical field
The utility model belongs to technical field of biological, particularly a kind of intelligent multi-function immunochromatographiassays assays instrument.
Background technology
The nm of gold immunochromatography technique is a kind of solid phase detection technique that is based upon on nano gold mark technology and the immunochromatography technique basis.The immunochromatographiassays assays appearance is meant and the supporting use of nm of gold immune chromatography test paper, utilizes the immunochromatography technique dynamic quantitative to detect the compound of certain molecular weight or the instant checkout equipment of biomarker.
The immunochromatographiassays assays appearance is a kind of extracorporeal diagnostic instrument; Promptly in the forecasting process of the diagnosis of disease, treatment monitoring, prognosis observation, health status evaluation and genetic disease, be used for human sample (various body fluid, cell, tissue samples etc.) is carried out the instrument of vitro detection.At present, the in-vitro diagnosis method is developed to reagent and instrument associating detection by quantitative by the reagent qualitative detection, and the present invention becomes detection system to utilize immunochromatographic method to carry out the dynamic quantitative detection gold marked reagent with instrument combination.
Clinical detection is easy to be quick to the requirement of quantitative detecting method, and the result is accurate, good reproducibility.The quantitative Diagnosis method of Clinical detection use at present comprises radioimmunoassay method, chemoluminescence method and ELISA etc.Wherein, the radioimmunoassay method produces the denier radioactive contamination; Chemoluminescence method needs large-scale instrument, and reagent cost is higher; ELISA only need dispose pertinent instruments, testing process length consuming time, complicated operation, and the experimenter need pass through special training.
The immunochromatographiassays assays appearance of the utility model is different from other Clinical detection quantitative detecting methods has following characteristics:
1) aims at the fast detecting scheme that the hospital clinical outpatient service designs.The characteristics of this fast detecting scheme are formed by bar code reader, coding chip reader, GSM/GPRS module and RS232/USB combination of interfaces; Can send testing result to patient with the form of packet radio; Time foreshortens to about 10 minutes, and has removed the patient scene from and waited the process of getting the result.。
2) detection is with low cost.Reduce detectable cost and hospital's human cost.
3) ease-to-operate: clinical use need not disposed various liquid reagents, and test item is accomplished automatically, can in ten minutes, obtain a result.
4) volume little, be convenient to move and carry: the motor-driven uses in various places such as first aid that can be in hospital, outpatient service, Inpatient Building, health check-up.
5) often adopt in the food safety detection and the similar technology of medical science detection.The utility model can be realized the dynamic quantitative of pathogenic bacteria, residues of pesticides, chemical addition agent etc. in the food is detected.When being used for the food security fast detecting, can be easy to carry makes things convenient for family to use to passing in and out port, country fair and even microminiaturization.
The utility model content
The utility model provides a kind of intelligent multi-function immunochromatographiassays assays instrument; It can make clinical gold-labelled diagnosis process by foreshortening to about 10 minutes half an hour approximately; Improved the efficient of hospital clinical outpatient service greatly; Saved medical resource, simplified seek medical advice interrogation--field diagnostic--of patient's queuing simultaneously and waited the process of report.
The utility model solves the technical scheme that its technical matters adopted: a kind of intelligent multi-function immunochromatographiassays assays instrument is provided, is made up of optoelectronic scanning disposal system, main circuit part and other function systems; Wherein, Carry out immunochromatography quantitative test signal acquisition process by the optoelectronic scanning disposal system; By main circuit partly carry out comprise power supply provide, with processes such as PERCOM peripheral communication, Photoelectric Signal Processing, move instruction, carry out checking matter information and typical curve reads, operation interface and output procedure as a result by other function systems.
Described optoelectronic scanning disposal system is made up of ray machine module and photoelectric circuit.
Described photoelectric circuit is made up of photo-sensor signal will circuit and photodiode radiating circuit.
Described main circuit part is made up of power circuit, telecommunication circuit, motherboard circuit and other functional circuits.
By described power circuit power supply is divided into the required power supply of mainboard, telecommunication circuit and the required power supply of functional circuit, required power supply three bulks of photoelectric circuit; Carry out communicating by letter between mainboard chip and the outside by described telecommunication circuit through the RS232/USB interface; The photosignal of the optoelectronic scanning disposal system being collected by described motherboard circuit carries out digital processing and calculating; And result shown or printer prints through liquid crystal display; Motherboard circuit also plays the effect of keyboard scan simultaneously, sends required operational order to motherboard circuit through the keyboard operator; Be responsible for sending the instruction that motherboard circuit sends to each functional module group by described other functional circuits.
Described other function systems comprise liquid crystal display, button part, bar code reader, coding chip reader, GSM/GPRS module, printer and RS232 and USB interface.
By described bar code reader typing checking matter information, the coding chip reader reads the standard working curve of test item and this project automatically; Send testing result to patient with the form of packet radio by described GSM/GPRS module; Automatically testing process and result data are conveyed into hospital system by described RS232/USB interface.
Described immunochromatography quantitative test signal is from the colour band district on the immune chromatography test paper, and the reflected light scioptics in said colour band district focus on the pixel of image sensing device, by the photo-sensor signal will circuit optical image are converted into digital signal.
Described digital signal is carried out analyzing and processing by motherboard circuit, obtains catoptrical strong and weak value or two catoptrical strong and weak correlative values in colour band district of wall scroll colour band.
Described colour band district is formed by nm of gold immunochromatography process
The apparatus structure of the utility model
Whole immunochromatographiassays assays appearance can be divided into optoelectronic scanning disposal system, main circuit part and other function system three parts.
1. optoelectronic scanning disposal system
The optoelectronic scanning disposal system is made up of ray machine module, photoelectric circuit two parts.Specifically comprise:
(1) ray machine module: shine one or two colour band district on the gold-marking immunity chromatographic test paper through even light glass by one to four light emitting diode; Article two, the light scioptics of colour band district reflection focus on the pixel of image sensing device, can be used for fast detecting according to catoptrical strong and weak value or two catoptrical strong and weak correlative values in colour band district of wall scroll colour band.
(2) photoelectric circuit: the photoelectric circuit part is divided into 2 sub-circuit again: photo-sensor signal will circuit and photodiode radiating circuit.Wherein the photo-sensor signal will circuit is responsible for the collection of photosignal, and optical image is converted into digital signal.The photodiode radiating circuit then is responsible for the control photodiode, thereby electric energy is converted into the colour band district of radiation of visible light gold-marking immunity chromatographic test paper.
2. main circuit part
The main circuit part is divided into 4 sub-circuit again: power circuit, telecommunication circuit, motherboard circuit and other functional circuits.Power circuit mainly is that power supply is divided into the required power supply of mainboard, telecommunication circuit and functional circuit, required power supply three bulks of photoelectric circuit (photo-sensor signal will circuit and photodiode radiating circuit); Telecommunication circuit is responsible for the mainboard chip and is communicated through the RS232/USB interface with outside; Motherboard circuit is responsible for digital processing and the calculating with the photosignal of optoelectronic scanning disposal system collection, and some results that will handle simultaneously show through liquid crystal display or printer prints is come out; Motherboard circuit also plays the effect of keyboard scan, sends required operational order to motherboard circuit through the keyboard operator; Other functional circuits are responsible for sending the instruction that motherboard circuit sends to each functional module group.
3. other function systems
Other function systems comprise liquid crystal display, button part, bar code reader, coding chip reader, GSM/GPRS module, printer, RS232 and USB interface.
(1) liquid crystal display: display device, such as the liquid crystal panel of planar ultra-thin, be responsible for to user's feedback information.
(2) button part: metallic bond, rubber key or PVC pad pasting are used for input instruction and data.
(3) bar code reader: for checking matter is equipped with bar code, read by bar code reader, thereby realize automatic typing checking matter information, comprise sequence number, detect date, test item etc.
(4) coding chip reader: with supporting nm of gold immune chromatography test paper coding chip is provided, reads the standard working curve of test item and this project through the coding chip reader.
(5) GSM/GPRS module: be responsible for sending testing result to recipient with the form of packet radio.
(6) printer: be responsible for the testing result printout.
(7) RS232 and USB interface: be responsible for being connected communication, also direct connecting terminal copy data with network.
Beneficial effect
The innovative point of this instrument is the fast detecting scheme that aims at hospital clinical outpatient service design that this instrument embodies, and the characteristics of this fast detecting scheme are brought by bar code reader, coding chip reader, GSM/GPRS module and RS232/USB combination of interfaces.Wherein, the automatic typing checking matter of bar code reader information comprises sequence number, detects date, test item etc., has save the doctor and has manually imported the process that writes down patient information; The coding chip reader reads the standard working curve of test item and this project automatically, has simplified diagnostic procedure; The GSM/GPRS module can send testing result to patient with the form of packet radio, has removed the patient scene from and has waited the process of getting diagnostic result; The RS232/USB interface is conveyed into hospital's diagnosis and therapy system with testing process and result data automatically.In addition; Through regulating the control response time; Use exclusive immunochromatography diagnose test paper; Be preferably the immunochromatography diagnose test paper of nano gold mark,, the testing process of this instrument be controlled at about 10 minutes like human chorionic gonadotrophin detectable, clenobuterol hydrochloride detectable and melamine (MEL) quick detection reagent of Shanghai Bai Na Bioisystech Co., Ltd.
In sum; The fast detecting scheme of this instrument can make clinical gold-labelled diagnosis process by foreshortening to about 10 minutes half an hour approximately; Improved the efficient of hospital clinical outpatient service greatly; Save medical resource, simplified seek medical advice interrogation--field diagnostic--of patient's queuing simultaneously and waited the process of report, had good novelty and practicality.
Description of drawings:
Fig. 1 complete machine is formed synoptic diagram: optoelectronic scanning disposal system=ray machine module+photoelectric circuit; Main circuit=motherboard circuit+power circuit+telecommunication circuit+other functional circuits
Embodiment
Embodiment 1: detect the nm of gold immune chromatography test paper
Open the primary power of instrument.Instrument self checking is waited in preheating 10 minutes simultaneously.The packing box of opening test strips takes out corrector strip afterwards, presses calibration knob, and instrument is calibrated automatically.Take out the coding chip coding in the packing box, read coding chip information by the method for embodiment 3.Method by embodiment 2 reads the checking matter bar code information by bar code reader.Checking matter sample such as blood sample, urine sample etc. are dripped in the well of nm of gold immune chromatography test paper, put into the test paper groove of instrument.Press the measurement button, instrument can detect at the appointed time automatically, and the record testing result, can be by the printer prints result, or send the result by the GSM/GPRS module, or preserve/duplicate the result by USB/RS232.
Embodiment 2: bar code reader reads bar code
Bar code reader is aligned to the barcode size or text field on the checking matter, presses and read button, then checking matter sequence number, the information such as date, test item that detect are read by bar code reader automatically, the typing instrument, and relevant information will be presented on the liquid crystal display.
Embodiment 3: coding chip reader reading coding chip
The coding chip that supporting nm of gold immune chromatography test paper is provided places the instrument induction zone, presses and reads button, and then the coding chip reader reads the test item of this test paper and the standard working curve of this project automatically, and is presented on the liquid crystal display.
Embodiment 4:GSM/GPRS module is sent information
At first selection needs the data of transmission, and the destination address of then information being sent is imported by keyboard, presses the transmission button, and then testing result sends to the recipient automatically.
Claims (10)
1. an intelligent multi-function immunochromatographiassays assays instrument is made up of optoelectronic scanning disposal system, main circuit part and other function systems; Wherein, Carry out immunochromatography quantitative test signal acquisition process by the optoelectronic scanning disposal system; By main circuit partly carry out comprise power supply provide, with processes such as PERCOM peripheral communication, Photoelectric Signal Processing, move instruction, carry out checking matter information and typical curve reads, operation interface and output procedure as a result by other function systems.
2. intelligent multi-function immunochromatographiassays assays instrument according to claim 1 is characterized in that described optoelectronic scanning disposal system is made up of ray machine module and photoelectric circuit.
3. intelligent multi-function immunochromatographiassays assays instrument according to claim 2 is characterized in that described photoelectric circuit is made up of photo-sensor signal will circuit and photodiode radiating circuit.
4. intelligent multi-function immunochromatographiassays assays instrument according to claim 1 is characterized in that, described main circuit part is made up of power circuit, telecommunication circuit, motherboard circuit and other functional circuits.
5. intelligent multi-function immunochromatographiassays assays instrument according to claim 4 is characterized in that, by described power circuit power supply is divided into the required power supply of mainboard, telecommunication circuit and the required power supply of functional circuit, required power supply three bulks of photoelectric circuit; Carry out communicating by letter between mainboard chip and the outside by described telecommunication circuit through the RS232/USB interface; The photosignal of the optoelectronic scanning disposal system being collected by described motherboard circuit carries out digital processing and calculating; And result shown or printer prints through liquid crystal display; Motherboard circuit also plays the effect of keyboard scan simultaneously, sends required operational order to motherboard circuit through the keyboard operator; Be responsible for sending the instruction that motherboard circuit sends to each functional module group by described other functional circuits.
6. intelligent multi-function immunochromatographiassays assays instrument according to claim 1; It is characterized in that described other function systems comprise liquid crystal display, button part, bar code reader, coding chip reader, GSM/GPRS module, printer and RS232 and USB interface.
7. intelligent multi-function immunochromatographiassays assays instrument according to claim 6 is characterized in that, by described bar code reader typing checking matter information, the coding chip reader reads the standard working curve of test item and this project automatically; Send testing result to patient with the form of packet radio by described GSM/GPRS module; Automatically testing process and result data are conveyed into hospital system by described RS232/USB interface.
8. intelligent multi-function immunochromatographiassays assays instrument according to claim 1; It is characterized in that; Described immunochromatography quantitative test signal is from the colour band district on the immune chromatography test paper; The reflected light scioptics in said colour band district focus on the pixel of image sensing device, by the photo-sensor signal will circuit optical image are converted into digital signal.
9. intelligent multi-function immunochromatographiassays assays instrument according to claim 8 is characterized in that described digital signal is carried out analyzing and processing by motherboard circuit, obtains catoptrical strong and weak value or two catoptrical strong and weak correlative values in colour band district of wall scroll colour band.
10. intelligent multi-function immunochromatographiassays assays instrument according to claim 8 is characterized in that described colour band district is formed by nm of gold immunochromatography process.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011201604301U CN202210101U (en) | 2011-05-19 | 2011-05-19 | Intelligent multifunctional immunity chromatography analysis instrument |
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| CN2011201604301U CN202210101U (en) | 2011-05-19 | 2011-05-19 | Intelligent multifunctional immunity chromatography analysis instrument |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103197060A (en) * | 2013-03-24 | 2013-07-10 | 湖南远泰生物技术有限公司 | Autonomous recognition, positioning and quantitative detecting system and detecting method for colloidal gold immunochromatographic boxes |
| CN103226145A (en) * | 2013-03-24 | 2013-07-31 | 湖南远泰生物技术有限公司 | Autonomous identification positioning and quantitative detection system of colloidal gold immunochromatography box |
| CN103245782A (en) * | 2013-04-27 | 2013-08-14 | 北京福乐云检测科技有限公司 | Colloidal gold method online detector |
| CN103245780A (en) * | 2013-04-27 | 2013-08-14 | 北京福乐云检测科技有限公司 | Colloidal gold anti-counterfeiting tracing cloud platform |
| WO2013166898A1 (en) * | 2012-05-08 | 2013-11-14 | Abon Biohparm (Hangzhou) Co., Ltd | A test strip for reading by an electric reading device and an electric reading device |
| CN103499699A (en) * | 2013-09-27 | 2014-01-08 | 南昌大学 | Fluorescent microsphere immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system |
| CN103499687A (en) * | 2013-09-27 | 2014-01-08 | 南昌大学 | Colloidal gold immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system |
| CN104297468A (en) * | 2013-07-15 | 2015-01-21 | 艾博生物医药(杭州)有限公司 | Immune reading apparatus and its calibration method |
| CN105223368A (en) * | 2014-07-02 | 2016-01-06 | 北京倍肯华业科技发展有限公司 | A kind of intelligent immunochromatographiassays assays device and analytical approach thereof |
| CN111497461A (en) * | 2020-05-26 | 2020-08-07 | 广东星创众谱仪器有限公司 | Intelligent machine for edible agricultural product qualification certificate and working method thereof |
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2011
- 2011-05-19 CN CN2011201604301U patent/CN202210101U/en not_active Expired - Fee Related
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013166898A1 (en) * | 2012-05-08 | 2013-11-14 | Abon Biohparm (Hangzhou) Co., Ltd | A test strip for reading by an electric reading device and an electric reading device |
| CN103197060A (en) * | 2013-03-24 | 2013-07-10 | 湖南远泰生物技术有限公司 | Autonomous recognition, positioning and quantitative detecting system and detecting method for colloidal gold immunochromatographic boxes |
| CN103226145A (en) * | 2013-03-24 | 2013-07-31 | 湖南远泰生物技术有限公司 | Autonomous identification positioning and quantitative detection system of colloidal gold immunochromatography box |
| CN103245782A (en) * | 2013-04-27 | 2013-08-14 | 北京福乐云检测科技有限公司 | Colloidal gold method online detector |
| CN103245780A (en) * | 2013-04-27 | 2013-08-14 | 北京福乐云检测科技有限公司 | Colloidal gold anti-counterfeiting tracing cloud platform |
| CN103245782B (en) * | 2013-04-27 | 2015-10-14 | 北京福乐云检测科技有限公司 | Colloidal gold method on-line detector |
| CN104297468A (en) * | 2013-07-15 | 2015-01-21 | 艾博生物医药(杭州)有限公司 | Immune reading apparatus and its calibration method |
| CN103499699A (en) * | 2013-09-27 | 2014-01-08 | 南昌大学 | Fluorescent microsphere immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system |
| CN103499687A (en) * | 2013-09-27 | 2014-01-08 | 南昌大学 | Colloidal gold immunochromatographic assay quantitative detector by combination of internet-of-things data transmission system |
| CN105223368A (en) * | 2014-07-02 | 2016-01-06 | 北京倍肯华业科技发展有限公司 | A kind of intelligent immunochromatographiassays assays device and analytical approach thereof |
| CN111497461A (en) * | 2020-05-26 | 2020-08-07 | 广东星创众谱仪器有限公司 | Intelligent machine for edible agricultural product qualification certificate and working method thereof |
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| C14 | Grant of patent or utility model | ||
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Owner name: SHANGHAI SAIAN BIOLOGICAL MEDICAL TECHNOLOGY CO., Free format text: FORMER OWNER: SHEN HEBAI Effective date: 20140526 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Free format text: CORRECT: ADDRESS; FROM: 200233 XUHUI, SHANGHAI TO: 200436 BAOSHAN, SHANGHAI |
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Effective date of registration: 20140526 Address after: 200436 Baoshan District, Shanghai, Shanghai Road, No. 1888 Wen Sheng building, floor, floor, No. 1, Shanghai Patentee after: Shanghai Saian Biological Medical Technology Co., Ltd. Address before: 200233, room 14, building 202, ring school, Shanghai normal college, No. 100, Xuhui District, Shanghai, Guilin Road Patentee before: Shen Hebai |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120502 Termination date: 20190519 |
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| CF01 | Termination of patent right due to non-payment of annual fee |