CN1989256A - 包含pef－ts表达单元的谷氨酸棒杆菌 - Google Patents

包含pef－ts表达单元的谷氨酸棒杆菌 Download PDF

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Publication number
CN1989256A
CN1989256A CNA2005800241401A CN200580024140A CN1989256A CN 1989256 A CN1989256 A CN 1989256A CN A2005800241401 A CNA2005800241401 A CN A2005800241401A CN 200580024140 A CN200580024140 A CN 200580024140A CN 1989256 A CN1989256 A CN 1989256A
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CN
China
Prior art keywords
nucleic acid
activity
coding
expression
gene
Prior art date
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Pending
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CNA2005800241401A
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English (en)
Chinese (zh)
Inventor
O·策尔德尔
C·克洛普罗格
B·克勒格尔
H·施罗德
S·哈夫纳
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BASF SE
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BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of CN1989256A publication Critical patent/CN1989256A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNA2005800241401A 2004-07-20 2005-07-16 包含pef－ts表达单元的谷氨酸棒杆菌 Pending CN1989256A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004035065.5 2004-07-20
DE102004035065A DE102004035065A1 (de) 2004-07-20 2004-07-20 P-ET-TS-Expressionseinheiten

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2007103011879A Division CN101230350A (zh) 2004-07-20 2005-07-16 包含pef－ts表达单元的谷氨酸棒杆菌

Publications (1)

Publication Number Publication Date
CN1989256A true CN1989256A (zh) 2007-06-27

Family

ID=35628646

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA2007103011879A Pending CN101230350A (zh) 2004-07-20 2005-07-16 包含pef－ts表达单元的谷氨酸棒杆菌
CNA2005800241401A Pending CN1989256A (zh) 2004-07-20 2005-07-16 包含pef－ts表达单元的谷氨酸棒杆菌

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CNA2007103011879A Pending CN101230350A (zh) 2004-07-20 2005-07-16 包含pef－ts表达单元的谷氨酸棒杆菌

Country Status (11)

Country Link
US (3) US20070269871A1 (enExample)
EP (2) EP1771574A2 (enExample)
JP (2) JP2008506400A (enExample)
KR (1) KR20070032076A (enExample)
CN (2) CN101230350A (enExample)
AT (1) ATE531819T1 (enExample)
BR (1) BRPI0513227A (enExample)
DE (1) DE102004035065A1 (enExample)
ES (1) ES2376035T3 (enExample)
PL (1) PL1942198T3 (enExample)
WO (1) WO2006008097A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108753810A (zh) * 2018-05-22 2018-11-06 昆明理工大学 一种转录调节蛋白基因orf2的用途
WO2019085445A1 (zh) * 2017-11-01 2019-05-09 北京中科伊品生物科技有限公司 生产l-赖氨酸的重组菌、其构建方法以及l-赖氨酸的生产方法

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DE102004061846A1 (de) 2004-12-22 2006-07-13 Basf Ag Mehrfachpromotoren
PL2082045T3 (pl) 2006-10-24 2015-07-31 Basf Se Sposób zmniejszania ekspresji genów poprzez modyfikację częstości występowania kodonów
KR100789274B1 (ko) * 2007-01-15 2008-01-02 씨제이 주식회사 코리네박테리움 글루타미쿰에서 유래한 신규한 프로모터핵산 분자, 그 프로모터를 포함하는 재조합 벡터, 그재조합 벡터를 포함하는 숙주 세포 및 그 숙주 세포를이용하여 유전자를 발현하는 방법
BRPI0807760A2 (pt) 2007-02-19 2014-06-17 Evonik Degussa Gmbh Bactérias corineformes com atividade de formato-thf-sintetase e/ou atividade de clivagem de glicina
WO2009133063A2 (en) * 2008-04-30 2009-11-05 Evonik Degussa Gmbh Production process for methionine using microorganisms with reduced isocitrate dehydrogenase activity
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
WO2010108542A1 (en) * 2009-03-25 2010-09-30 Nestec S.A. A natural taste enhancing savoury base and a process for its preparation
PL3199511T3 (pl) * 2009-06-04 2020-05-18 Genomatica, Inc. Sposób oddzielania składników brzeczki fermentacyjnej
AR086790A1 (es) 2011-06-29 2014-01-22 Metabolic Explorer Sa Un microorganismo para la produccion de metionina con importacion de glucosa mejorada
KR101944150B1 (ko) 2012-06-18 2019-01-30 에보니크 데구사 게엠베하 메티오닌의 발효적 생산을 위한 재조합 미생물
KR102270626B1 (ko) 2013-08-30 2021-06-30 에보니크 오퍼레이션즈 게엠베하 메티오닌 신타제 활성 및 메티오닌 유출이 개선된 메티오닌 생산용 미생물
JP2017525379A (ja) 2014-09-01 2017-09-07 メタボリック エクスプローラー メチオニン排出を改善した発酵によるメチオニン産生の方法及び微生物
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN108026516A (zh) 2015-08-07 2018-05-11 赢创德固赛有限公司 通过发酵的蛋白硫代羧化物依赖性l-甲硫氨酸生产
CN108291243A (zh) 2015-11-27 2018-07-17 赢创德固赛有限公司 生产l-甲硫氨酸的方法
EP3296404A1 (en) 2016-09-15 2018-03-21 Evonik Degussa GmbH Modified microorganism for production of methionine
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria

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GB2165546B (en) 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
DE4027453A1 (de) 1990-08-30 1992-03-05 Degussa Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren
DE69529026T2 (de) 1994-07-19 2003-07-17 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Trehalose, ihre Herstellung und ihre Verwendung
DE4440118C1 (de) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Die Genexpression in coryneformen Bakterien regulierende DNA
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JP3711658B2 (ja) 1996-10-07 2005-11-02 味の素株式会社 コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質
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KR100630604B1 (ko) 1998-09-25 2006-10-04 아지노모토 가부시키가이샤 아미노산 생산균의 작제 방법 및 작제된 아미노산생산균을 사용하는 발효법에 의한 아미노산의 제조 방법
SK18862001A3 (sk) 1999-06-25 2002-11-06 Basf Aktiengesellschaft Gény Corynebacterium glutamicum kódujúce proteíny metabolických dráh
US7892798B2 (en) * 1999-06-25 2011-02-22 Evonik Degussa Gmbh Nucleic acid molecules encoding metabolic regulatory proteins from Corynebacterium glutamicum, useful for increasing the production of methionone by a microorganism
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019085445A1 (zh) * 2017-11-01 2019-05-09 北京中科伊品生物科技有限公司 生产l-赖氨酸的重组菌、其构建方法以及l-赖氨酸的生产方法
CN108753810A (zh) * 2018-05-22 2018-11-06 昆明理工大学 一种转录调节蛋白基因orf2的用途
CN108753810B (zh) * 2018-05-22 2021-06-18 昆明理工大学 一种转录调节蛋白基因orf2的用途

Also Published As

Publication number Publication date
US20140242704A1 (en) 2014-08-28
WO2006008097A3 (de) 2006-10-05
CN101230350A (zh) 2008-07-30
US20080176295A1 (en) 2008-07-24
BRPI0513227A (pt) 2008-04-29
ATE531819T1 (de) 2011-11-15
JP5710096B2 (ja) 2015-04-30
US20070269871A1 (en) 2007-11-22
WO2006008097A2 (de) 2006-01-26
EP1771574A2 (de) 2007-04-11
US8735159B2 (en) 2014-05-27
DE102004035065A1 (de) 2006-02-16
PL1942198T3 (pl) 2012-04-30
EP1942198B1 (de) 2011-11-02
KR20070032076A (ko) 2007-03-20
ES2376035T3 (es) 2012-03-08
EP1942198A2 (de) 2008-07-09
JP2008212156A (ja) 2008-09-18
EP1942198A3 (de) 2008-10-01
JP2008506400A (ja) 2008-03-06

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C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication