CN1957093B - 使用含有环氧基的聚合物涂层的塑料基片的pna芯片、制造该pna芯片的方法和使用该pna芯片检测单核苷酸多态性的方法 - Google Patents
使用含有环氧基的聚合物涂层的塑料基片的pna芯片、制造该pna芯片的方法和使用该pna芯片检测单核苷酸多态性的方法 Download PDFInfo
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- CN1957093B CN1957093B CN2005800161981A CN200580016198A CN1957093B CN 1957093 B CN1957093 B CN 1957093B CN 2005800161981 A CN2005800161981 A CN 2005800161981A CN 200580016198 A CN200580016198 A CN 200580016198A CN 1957093 B CN1957093 B CN 1957093B
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- pna
- plastic substrate
- epoxy
- polymer
- acrylate
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/0427—Coating with only one layer of a composition containing a polymer binder
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- C—CHEMISTRY; METALLURGY
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- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/043—Improving the adhesiveness of the coatings per se, e.g. forming primers
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- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
- C09D133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
- C09D133/062—Copolymers with monomers not covered by C09D133/06
- C09D133/068—Copolymers with monomers not covered by C09D133/06 containing glycidyl groups
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D163/00—Coating compositions based on epoxy resins; Coating compositions based on derivatives of epoxy resins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00378—Piezoelectric or ink jet dispensers
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- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2463/00—Characterised by the use of epoxy resins; Derivatives of epoxy resins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2525/107—Modifications characterised by incorporating a peptide nucleic acid
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- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Composite Materials (AREA)
- General Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020040047677A KR100766752B1 (ko) | 2004-06-24 | 2004-06-24 | 에폭시기를 갖는 중합체가 코팅된 플라스틱 기판을 이용한pna 칩 |
| KR1020040047677 | 2004-06-24 | ||
| KR10-2004-0047677 | 2004-06-24 | ||
| PCT/KR2005/001920 WO2006001627A1 (en) | 2004-06-24 | 2005-06-21 | Pna chip using plastic substrate coated with epoxy group-containing polymer, method of manufacturing the pna chip, and method of detecting single nucleotide polymorphism using the pna chip |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1957093A CN1957093A (zh) | 2007-05-02 |
| CN1957093B true CN1957093B (zh) | 2011-04-13 |
Family
ID=36640918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2005800161981A Expired - Fee Related CN1957093B (zh) | 2004-06-24 | 2005-06-21 | 使用含有环氧基的聚合物涂层的塑料基片的pna芯片、制造该pna芯片的方法和使用该pna芯片检测单核苷酸多态性的方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7696130B2 (OSRAM) |
| EP (1) | EP1759016A4 (OSRAM) |
| JP (1) | JP4510080B2 (OSRAM) |
| KR (1) | KR100766752B1 (OSRAM) |
| CN (1) | CN1957093B (OSRAM) |
| AU (1) | AU2005257596B2 (OSRAM) |
| CA (1) | CA2563948A1 (OSRAM) |
| TW (1) | TWI282371B (OSRAM) |
| WO (1) | WO2006001627A1 (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100653975B1 (ko) * | 2004-11-30 | 2006-12-05 | 한국과학기술원 | 집코드 방식을 이용한 pna 칩 및 이의 제작방법 |
| KR100725579B1 (ko) * | 2005-02-16 | 2007-06-08 | 주식회사 엘지생명과학 | 에폭시기를 갖는 중합체가 코팅된 플라스틱 기판을 이용한마이코박테리아 유전자형 검출용 pna 칩 및 그를 이용한마이코박테리아 유전자형 검출 방법 |
| US9051667B2 (en) * | 2007-10-26 | 2015-06-09 | Wisconsin Alumni Research Foundation | Substrate independent copolymers for biofunctionalization |
| KR100943421B1 (ko) * | 2007-12-24 | 2010-02-19 | 연세대학교 산학협력단 | 에폭시기와 불포화이중결합을 갖는 광중합성 단량체 및이를 함유한 광중합 조성물 |
| EP2311977A1 (en) | 2009-10-15 | 2011-04-20 | INSERM (Institut National de la Santé et de la Recherche Medicale) | Method for predicting responsiveness of a patient to a chemoradiation treatment |
| WO2012120129A1 (en) | 2011-03-10 | 2012-09-13 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical composition for the treatment of infectious diseases |
| CA2864080C (en) | 2012-02-07 | 2023-04-25 | Vibrant Holdings, Llc | Substrates, peptide arrays, and methods |
| US10006909B2 (en) | 2012-09-28 | 2018-06-26 | Vibrant Holdings, Llc | Methods, systems, and arrays for biomolecular analysis |
| CA3009812A1 (en) * | 2015-12-28 | 2017-07-06 | Vibrant Holdings, Llc | Substrates, systems, and methods for nucleic acid array synthesis |
| WO2017170994A1 (ja) | 2016-03-31 | 2017-10-05 | 古河電気工業株式会社 | 細胞収容チップ |
| WO2018218250A2 (en) | 2017-05-26 | 2018-11-29 | Vibrant Holdings, Llc | Photoactive compounds and methods for biomolecule detection and sequencing |
| JP7422087B2 (ja) | 2018-05-09 | 2024-01-25 | ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー | 光活性化された作用物質を使用してポリヌクレオチドアレイを合成する方法 |
| CN116832724A (zh) * | 2023-05-18 | 2023-10-03 | 天津大学 | 一种高载量核酸合成芯片及其制备方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1352976A2 (en) * | 1997-08-01 | 2003-10-15 | Canon Kabushiki Kaisha | Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0842960A4 (en) * | 1996-06-03 | 1999-09-22 | Toyo Ink Mfg Co | SOLIDIFIABLE LIQUID RESIN COMPOSITION |
| US6713255B1 (en) | 1999-06-07 | 2004-03-30 | Fuji Photo Film Co., Ltd. | DNA chip, PNA chip, and their preparation methods |
| KR100359941B1 (ko) * | 2000-04-14 | 2002-11-07 | 엘지전자 주식회사 | 바이오칩 제조방법 |
| DE60033665T2 (de) * | 2000-10-31 | 2007-10-31 | Micronas Gmbh | Gemusterte Polymeroberflächen geeignet für Biokonjugationen und Verfahren zu ihrer Herstellung |
| US7205161B2 (en) * | 2001-01-10 | 2007-04-17 | Symyx Technologies, Inc. | Polymer brushes for immobilizing molecules to a surface or substrate having improved stability |
| US20030109062A1 (en) * | 2001-06-05 | 2003-06-12 | Hiroko Inomata | Reactive solid support and DNA fragment detection tool |
| JP3824523B2 (ja) * | 2001-11-29 | 2006-09-20 | 住友ベークライト株式会社 | マイクロチップ用基板及びマイクロチップ |
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2004
- 2004-06-24 KR KR1020040047677A patent/KR100766752B1/ko not_active Expired - Fee Related
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2005
- 2005-06-21 JP JP2007513078A patent/JP4510080B2/ja not_active Expired - Fee Related
- 2005-06-21 CN CN2005800161981A patent/CN1957093B/zh not_active Expired - Fee Related
- 2005-06-21 EP EP05765833A patent/EP1759016A4/en not_active Withdrawn
- 2005-06-21 WO PCT/KR2005/001920 patent/WO2006001627A1/en not_active Ceased
- 2005-06-21 US US11/156,653 patent/US7696130B2/en not_active Expired - Fee Related
- 2005-06-21 AU AU2005257596A patent/AU2005257596B2/en not_active Ceased
- 2005-06-21 TW TW094120545A patent/TWI282371B/zh not_active IP Right Cessation
- 2005-06-21 CA CA002563948A patent/CA2563948A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1352976A2 (en) * | 1997-08-01 | 2003-10-15 | Canon Kabushiki Kaisha | Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array |
Also Published As
| Publication number | Publication date |
|---|---|
| JP4510080B2 (ja) | 2010-07-21 |
| EP1759016A1 (en) | 2007-03-07 |
| AU2005257596B2 (en) | 2008-06-12 |
| AU2005257596A1 (en) | 2006-01-05 |
| TWI282371B (en) | 2007-06-11 |
| EP1759016A4 (en) | 2008-10-08 |
| US7696130B2 (en) | 2010-04-13 |
| TW200600586A (en) | 2006-01-01 |
| KR100766752B1 (ko) | 2007-10-17 |
| CA2563948A1 (en) | 2006-01-05 |
| CN1957093A (zh) | 2007-05-02 |
| JP2007536554A (ja) | 2007-12-13 |
| KR20050122544A (ko) | 2005-12-29 |
| WO2006001627A1 (en) | 2006-01-05 |
| US20060147949A1 (en) | 2006-07-06 |
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