CN1939532B - 真菌免疫调节蛋白之用途 - Google Patents

真菌免疫调节蛋白之用途 Download PDF

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Publication number
CN1939532B
CN1939532B CN2006101270427A CN200610127042A CN1939532B CN 1939532 B CN1939532 B CN 1939532B CN 2006101270427 A CN2006101270427 A CN 2006101270427A CN 200610127042 A CN200610127042 A CN 200610127042A CN 1939532 B CN1939532 B CN 1939532B
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cell
fip
gts
protein
ganoderma
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CN1939532A (zh
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陈子智
柯俊良
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Yeastern Biotech Co Ltd
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Yeastern Biotech Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/375—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Basidiomycetes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/91245—Nucleotidyltransferases (2.7.7)
    • G01N2333/9125—Nucleotidyltransferases (2.7.7) with a definite EC number (2.7.7.-)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • General Physics & Mathematics (AREA)
  • Botany (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
CN2006101270427A 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途 Expired - Fee Related CN1939532B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/233,364 US20070071766A1 (en) 2005-09-23 2005-09-23 Compositions comprising fungal immunomodulatory protein and use thereof
US11/233,364 2005-09-23

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN2010101120159A Division CN101926979B (zh) 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途
CN2009101376694A Division CN101628110B (zh) 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途

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CN1939532A CN1939532A (zh) 2007-04-04
CN1939532B true CN1939532B (zh) 2012-10-31

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CN2006101270427A Expired - Fee Related CN1939532B (zh) 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途
CN2009101376694A Expired - Fee Related CN101628110B (zh) 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途
CN2010101120159A Expired - Fee Related CN101926979B (zh) 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途

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CN2009101376694A Expired - Fee Related CN101628110B (zh) 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途
CN2010101120159A Expired - Fee Related CN101926979B (zh) 2005-09-23 2006-09-21 真菌免疫调节蛋白之用途

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US (1) US20070071766A1 (enExample)
EP (2) EP1800690A3 (enExample)
JP (2) JP5117696B2 (enExample)
CN (3) CN1939532B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101475632B (zh) * 2008-01-03 2012-01-04 张喜田 具有抗肿瘤作用的重组灵芝免疫调节蛋白及其药物制剂
US20090285789A1 (en) * 2008-05-16 2009-11-19 Yeastern Biotech Co., Ltd Methods for enhancing innate and adaptive immunity and antigen immunogenicity
US8628785B2 (en) 2008-05-16 2014-01-14 Yeastern Biotech Co., Ltd Method for augmenting the immunogenicity of an antigen
TWI606835B (zh) * 2010-04-23 2017-12-01 中央研究院 基於靈芝多醣之組合物及治療癌症之方法
CN102199202B (zh) * 2011-03-22 2013-05-01 上海交通大学 灵芝属间的重组真菌免疫调节蛋白基因、该基因编码的蛋白及其应用
CN102199201B (zh) * 2011-03-22 2013-05-01 上海交通大学 灵芝属内重组的真菌免疫调节蛋白基因、该基因编码的蛋白及其应用
CN102241751B (zh) * 2011-04-20 2013-06-26 中国农业科学院饲料研究所 一种具有抗肿瘤活性的新型真菌免疫调节蛋白fip-nha及其基因
CN103243116B (zh) * 2013-05-08 2015-05-27 上海交通大学 一种属内重组真菌免疫调节蛋白的制备方法及其应用
CN104212828A (zh) * 2013-06-03 2014-12-17 怀化学院 一种重组茯苓免疫调节蛋白wcfip1及其抗体的生产方法
CN103417953B (zh) * 2013-08-16 2015-06-17 张喜田 重组灵芝免疫调节蛋白(rLZ-8)在制备治疗黑色素瘤药物中的应用
CN103739684B (zh) * 2014-01-09 2016-10-05 上海交通大学 黑灵芝真菌免疫调节蛋白的制备方法及其应用
TWI608846B (zh) * 2014-03-13 2017-12-21 益生生技開發股份有限公司 用於改善化學治療所造成之不良副作用的組合療法
CN104001154B (zh) * 2014-06-10 2015-07-01 张喜田 重组灵芝免疫调节蛋白在制备治疗雄激素性脱发药物中的应用
TWI657821B (zh) * 2014-09-02 2019-05-01 益生生技開發股份有限公司 用於治療ｃ－ｍｅｔ相關性癌症的方法和組成物
CN107287166B (zh) * 2016-04-13 2021-04-09 蘑法生物科技股份有限公司 抗蕈类免疫调节蛋白的单株抗体及其应用
TWI702292B (zh) * 2018-12-28 2020-08-21 薩摩亞商康多富國際有限公司 個人化新陳代謝疾病保健食品組合的決定方法及非暫態電腦可讀取儲存媒體
US11141458B2 (en) * 2019-07-17 2021-10-12 Mycomagic Biotechnology Co., Ltd. Composition and methods for promoting and treating chronic wound healing
CN112646009B (zh) * 2019-08-27 2022-02-08 上海交通大学 灵芝免疫调节蛋白突变体及应用
CN113893337A (zh) * 2021-08-31 2022-01-07 中山大学 Dtx2蛋白在制备调控端粒酶活性的制剂中的应用
CN113768812A (zh) * 2021-09-08 2021-12-10 上海交通大学 重组真菌免疫调节蛋白rFIP-glu的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005040375A1 (en) * 2003-09-17 2005-05-06 Yeastern Biotech Co., Ltd. A fungal immuromodulatory protein produced by microorganisme and uses thereof

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
JP2000270713A (ja) * 1999-03-23 2000-10-03 Kennetto:Kk 糖尿病態モデル動物及びその製造方法並びに糖尿病態モデル動物の選定方法
GB0308988D0 (en) * 2003-04-17 2003-05-28 Univ Singapore Molecule
KR20060031809A (ko) * 2003-06-09 2006-04-13 더 리젠츠 오브 더 유니버시티 오브 미시간 암 치료 및 진단용 조성물 및 방법
JP2005224205A (ja) * 2004-02-16 2005-08-25 Hokko Chem Ind Co Ltd 健康食品

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005040375A1 (en) * 2003-09-17 2005-05-06 Yeastern Biotech Co., Ltd. A fungal immuromodulatory protein produced by microorganisme and uses thereof

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Publication number Publication date
EP1800690A3 (en) 2007-07-04
CN1939532A (zh) 2007-04-04
CN101628110A (zh) 2010-01-20
CN101628110B (zh) 2012-09-12
EP2759304B1 (en) 2016-09-21
CN101926979A (zh) 2010-12-29
HK1144373A1 (en) 2011-02-18
JP5117696B2 (ja) 2013-01-16
EP1800690A2 (en) 2007-06-27
US20070071766A1 (en) 2007-03-29
JP2007084547A (ja) 2007-04-05
EP2759304A1 (en) 2014-07-30
JP5512769B2 (ja) 2014-06-04
CN101926979B (zh) 2012-09-26
JP2012250991A (ja) 2012-12-20

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