JP5117696B2 - 真菌免疫調節タンパク質の使用 - Google Patents

真菌免疫調節タンパク質の使用 Download PDF

Info

Publication number
JP5117696B2
JP5117696B2 JP2006256232A JP2006256232A JP5117696B2 JP 5117696 B2 JP5117696 B2 JP 5117696B2 JP 2006256232 A JP2006256232 A JP 2006256232A JP 2006256232 A JP2006256232 A JP 2006256232A JP 5117696 B2 JP5117696 B2 JP 5117696B2
Authority
JP
Japan
Prior art keywords
cells
fip
gts
cell
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006256232A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007084547A5 (enExample
JP2007084547A (ja
Inventor
ツー−チー・シェン
ジウン−リアン・コー
Original Assignee
益生生抜▲開▼▲発▼股▲フン▼有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 益生生抜▲開▼▲発▼股▲フン▼有限公司 filed Critical 益生生抜▲開▼▲発▼股▲フン▼有限公司
Publication of JP2007084547A publication Critical patent/JP2007084547A/ja
Publication of JP2007084547A5 publication Critical patent/JP2007084547A5/ja
Application granted granted Critical
Publication of JP5117696B2 publication Critical patent/JP5117696B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/375—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Basidiomycetes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/91245—Nucleotidyltransferases (2.7.7)
    • G01N2333/9125—Nucleotidyltransferases (2.7.7) with a definite EC number (2.7.7.-)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • General Physics & Mathematics (AREA)
  • Botany (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
JP2006256232A 2005-09-23 2006-09-21 真菌免疫調節タンパク質の使用 Expired - Fee Related JP5117696B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/233,364 US20070071766A1 (en) 2005-09-23 2005-09-23 Compositions comprising fungal immunomodulatory protein and use thereof
US11/233,364 2005-09-23

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012198201A Division JP5512769B2 (ja) 2005-09-23 2012-09-10 真菌免疫調節タンパク質の使用

Publications (3)

Publication Number Publication Date
JP2007084547A JP2007084547A (ja) 2007-04-05
JP2007084547A5 JP2007084547A5 (enExample) 2009-11-05
JP5117696B2 true JP5117696B2 (ja) 2013-01-16

Family

ID=37894299

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006256232A Expired - Fee Related JP5117696B2 (ja) 2005-09-23 2006-09-21 真菌免疫調節タンパク質の使用
JP2012198201A Expired - Fee Related JP5512769B2 (ja) 2005-09-23 2012-09-10 真菌免疫調節タンパク質の使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012198201A Expired - Fee Related JP5512769B2 (ja) 2005-09-23 2012-09-10 真菌免疫調節タンパク質の使用

Country Status (4)

Country Link
US (1) US20070071766A1 (enExample)
EP (2) EP1800690A3 (enExample)
JP (2) JP5117696B2 (enExample)
CN (3) CN1939532B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101475632B (zh) * 2008-01-03 2012-01-04 张喜田 具有抗肿瘤作用的重组灵芝免疫调节蛋白及其药物制剂
US20090285789A1 (en) * 2008-05-16 2009-11-19 Yeastern Biotech Co., Ltd Methods for enhancing innate and adaptive immunity and antigen immunogenicity
US8628785B2 (en) 2008-05-16 2014-01-14 Yeastern Biotech Co., Ltd Method for augmenting the immunogenicity of an antigen
TWI606835B (zh) * 2010-04-23 2017-12-01 中央研究院 基於靈芝多醣之組合物及治療癌症之方法
CN102199202B (zh) * 2011-03-22 2013-05-01 上海交通大学 灵芝属间的重组真菌免疫调节蛋白基因、该基因编码的蛋白及其应用
CN102199201B (zh) * 2011-03-22 2013-05-01 上海交通大学 灵芝属内重组的真菌免疫调节蛋白基因、该基因编码的蛋白及其应用
CN102241751B (zh) * 2011-04-20 2013-06-26 中国农业科学院饲料研究所 一种具有抗肿瘤活性的新型真菌免疫调节蛋白fip-nha及其基因
CN103243116B (zh) * 2013-05-08 2015-05-27 上海交通大学 一种属内重组真菌免疫调节蛋白的制备方法及其应用
CN104212828A (zh) * 2013-06-03 2014-12-17 怀化学院 一种重组茯苓免疫调节蛋白wcfip1及其抗体的生产方法
CN103417953B (zh) * 2013-08-16 2015-06-17 张喜田 重组灵芝免疫调节蛋白(rLZ-8)在制备治疗黑色素瘤药物中的应用
CN103739684B (zh) * 2014-01-09 2016-10-05 上海交通大学 黑灵芝真菌免疫调节蛋白的制备方法及其应用
TWI608846B (zh) * 2014-03-13 2017-12-21 益生生技開發股份有限公司 用於改善化學治療所造成之不良副作用的組合療法
CN104001154B (zh) * 2014-06-10 2015-07-01 张喜田 重组灵芝免疫调节蛋白在制备治疗雄激素性脱发药物中的应用
TWI657821B (zh) * 2014-09-02 2019-05-01 益生生技開發股份有限公司 用於治療ｃ－ｍｅｔ相關性癌症的方法和組成物
CN107287166B (zh) * 2016-04-13 2021-04-09 蘑法生物科技股份有限公司 抗蕈类免疫调节蛋白的单株抗体及其应用
TWI702292B (zh) * 2018-12-28 2020-08-21 薩摩亞商康多富國際有限公司 個人化新陳代謝疾病保健食品組合的決定方法及非暫態電腦可讀取儲存媒體
US11141458B2 (en) * 2019-07-17 2021-10-12 Mycomagic Biotechnology Co., Ltd. Composition and methods for promoting and treating chronic wound healing
CN112646009B (zh) * 2019-08-27 2022-02-08 上海交通大学 灵芝免疫调节蛋白突变体及应用
CN113893337A (zh) * 2021-08-31 2022-01-07 中山大学 Dtx2蛋白在制备调控端粒酶活性的制剂中的应用
CN113768812A (zh) * 2021-09-08 2021-12-10 上海交通大学 重组真菌免疫调节蛋白rFIP-glu的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000270713A (ja) * 1999-03-23 2000-10-03 Kennetto:Kk 糖尿病態モデル動物及びその製造方法並びに糖尿病態モデル動物の選定方法
GB0308988D0 (en) * 2003-04-17 2003-05-28 Univ Singapore Molecule
KR20060031809A (ko) * 2003-06-09 2006-04-13 더 리젠츠 오브 더 유니버시티 오브 미시간 암 치료 및 진단용 조성물 및 방법
TWI328038B (en) * 2003-09-17 2010-08-01 Yeastern Biotech Co Ltd Fungal immunomodulatory protein (fip) prepared by microorganisms and uses thereof
JP2005224205A (ja) * 2004-02-16 2005-08-25 Hokko Chem Ind Co Ltd 健康食品

Also Published As

Publication number Publication date
EP1800690A3 (en) 2007-07-04
CN1939532A (zh) 2007-04-04
CN101628110A (zh) 2010-01-20
CN1939532B (zh) 2012-10-31
CN101628110B (zh) 2012-09-12
EP2759304B1 (en) 2016-09-21
CN101926979A (zh) 2010-12-29
HK1144373A1 (en) 2011-02-18
EP1800690A2 (en) 2007-06-27
US20070071766A1 (en) 2007-03-29
JP2007084547A (ja) 2007-04-05
EP2759304A1 (en) 2014-07-30
JP5512769B2 (ja) 2014-06-04
CN101926979B (zh) 2012-09-26
JP2012250991A (ja) 2012-12-20

Similar Documents

Publication Publication Date Title
JP5512769B2 (ja) 真菌免疫調節タンパク質の使用
Wong et al. Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials
JP5265333B2 (ja) 細胞死を調節する細胞障害性因子
Mori et al. Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection
EA013375B1 (ru) МОДУЛЯЦИЯ ИММУНОСТИМУЛИРУЮЩИХ СВОЙСТВ КОРОТКОЙ ИНТЕРФЕРИРУЮЩЕЙ РИБОНУКЛЕИНОВОЙ КИСЛОТЫ (siРНК) С ПОМОЩЬЮ МОДИФИКАЦИИ НУКЛЕОТИДОВ
Scarabel et al. Pharmacological strategies to prevent SARS-CoV-2 infection and treat the early phases of COVID-19
Ahn et al. Role of inflammasome regulation on immune modulators
Shin et al. Immunostimulatory effects of cordycepin‐enriched WIB‐801CE from Cordyceps militaris in splenocytes and cyclophosphamide‐induced immunosuppressed mice
Shin et al. Immunostimulatory Effects of Cordyceps militaris on Macrophages through the Enhanced Production of Cytokines via the Activation of NF-κB
Rogerio et al. Anti-asthmatic potential of a D-galactose-binding lectin from Synadenium carinatum latex
KR20160042875A (ko) 바이러스 면역치료 약물 복합체 및 이의 용도
EA013468B1 (ru) Иммуностимулирующая одноцепочечная рибонуклеиновая кислота с фосфодиэфирным остовом
US8629096B2 (en) Compositions comprising fungal immunomodulatory protein and use thereof
US20230165918A1 (en) Reduction of cytokine storm and pathological inflammation including caused by coronavirus using sphagnum and extracts thereof
Liz et al. The anti‐inflammatory modulatory role of Solidago chilensis Meyen in the murine model of the air pouch
TW202128203A (zh) 預防癌症復發的組成物及方法
Zhang et al. Lipid extract from completely sporoderm‐broken germinating Ganoderma sinensis spores elicits potent antitumor immune responses in human macrophages
KR100607907B1 (ko) 암의 간전이억제와 면역조절효과를 갖는 상황버섯추출물을 함유하는 약학적 조성물
WO2018102375A1 (en) Methods and compositions for cancer therapy
TWI360423B (en) Compositions comprising fungal immunomodulatory pr
JP2009276245A (ja) 持続性皮膚炎症性疾患の改善剤をスクリーニングする方法及びその改善剤
HK1144373B (en) Use of fungal immunomodulatory protein
Khatri Role of mucin 1 in Malaria-Associated Acute Respiratory Distress Syndrome
Ma Intracellular parasitism of macrophages by Cryptococcus
Pu et al. The role and mechanism of dandelionol in protecting gastric epithelial cells by regulating AMPK

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070514

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090911

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090911

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120214

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120511

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120612

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120910

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20121002

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20121018

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

Ref document number: 5117696

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20151026

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees