CN1913878B - 无需渗透促进剂的激素透皮传递 - Google Patents
无需渗透促进剂的激素透皮传递 Download PDFInfo
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- CN1913878B CN1913878B CN2004800413210A CN200480041321A CN1913878B CN 1913878 B CN1913878 B CN 1913878B CN 2004800413210 A CN2004800413210 A CN 2004800413210A CN 200480041321 A CN200480041321 A CN 200480041321A CN 1913878 B CN1913878 B CN 1913878B
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- Prior art keywords
- gestodene
- medicated layer
- compositions
- layer
- estrogen
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
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- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Applications Claiming Priority (5)
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| US52871803P | 2003-12-12 | 2003-12-12 | |
| US60/528,718 | 2003-12-12 | ||
| EP03078881 | 2003-12-12 | ||
| EP03078881.4 | 2003-12-12 | ||
| PCT/IB2004/052752 WO2005058287A2 (en) | 2003-12-12 | 2004-12-10 | Transdermal delivery system of hormones without penetration enhancers |
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| CN2010101564978A Division CN101843603B (zh) | 2003-12-12 | 2004-12-10 | 无需渗透促进剂的激素透皮传递 |
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| CN1913878A CN1913878A (zh) | 2007-02-14 |
| CN1913878B true CN1913878B (zh) | 2010-05-26 |
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| JP (1) | JP4965263B2 (und) |
| KR (1) | KR101168449B1 (und) |
| CN (1) | CN1913878B (und) |
| AU (1) | AU2004298930B2 (und) |
| BR (1) | BRPI0417530B8 (und) |
| CA (1) | CA2549916C (und) |
| CU (1) | CU23868B1 (und) |
| EA (1) | EA011160B1 (und) |
| EC (1) | ECSP066694A (und) |
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE333271T1 (de) | 2003-02-21 | 2006-08-15 | Schering Ag | Uv-stabiles transdermales pflaster |
| US8962013B2 (en) | 2005-05-02 | 2015-02-24 | Bayer Intellectual Property Gmbh | Multi-layered transdermal system with triazine UV absorber |
| DE102005050729A1 (de) * | 2005-10-19 | 2007-04-26 | Schering Ag | Verfahren zur präventiven bedarfsweisen hormonalen Kontrazeption |
| FR2900048B1 (fr) * | 2006-04-21 | 2012-11-16 | Oreal | Compositions comprenant un derive diphenyl-methane hydroxyle |
| DE102010040299A1 (de) | 2010-09-06 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Transdermale therapeutische Systeme mit kristallisationsinhibierender Schutzfolie (Release Liner) |
| DK2613772T3 (en) | 2010-09-06 | 2017-03-06 | Bayer Ip Gmbh | TRANSDERMAL LOW DOSAGE PATTERNS WITH HIGH PHARMACEUTICAL RELEASE |
| AU2015203180B2 (en) * | 2010-09-06 | 2016-06-30 | Bayer Intellectual Property Gmbh | Transdermal therapeutic systems with crystallization-inhibiting protective film (release liner) |
| EP2806862A2 (en) * | 2012-01-27 | 2014-12-03 | Agile Therapeutics, Inc. | Transdermal hormone delivery |
| US20180125860A1 (en) * | 2015-05-18 | 2018-05-10 | Agile Therapeutics, Inc. | Contraceptive Compositions and Methods for Improved Efficacy and Modulation of Side Effects |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0573133A1 (de) * | 1988-10-27 | 1993-12-08 | Schering Aktiengesellschaft | Mittel zur transdermalen Applikation das Gestoden enthält |
| US5512292A (en) * | 1990-10-29 | 1996-04-30 | Alza Corporation | Transdermal contraceptive formulations methods and devices |
| US5858394A (en) * | 1993-08-26 | 1999-01-12 | Schering Aktiengesellschaft | Agent for transdermal administration that contains gestodene esters |
| US5904931A (en) * | 1994-02-18 | 1999-05-18 | Schering Aktiengesellschaft | Transdermal therapeutic systems that contain sex steroids and dimethyl isosorbide |
| DE19906152B4 (de) * | 1999-02-10 | 2005-02-10 | Jenapharm Gmbh & Co. Kg | Wirkstoffhaltige Laminate für Transdermalsysteme |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992007590A1 (en) * | 1990-10-29 | 1992-05-14 | Alza Corporation | Transdermal contraceptive formulations, methods and devices |
| AU692944B2 (en) * | 1994-11-18 | 1998-06-18 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneously absorbable patch |
| ES2190472T5 (es) * | 1995-06-07 | 2012-03-09 | Ortho-Mcneil Pharmaceutical, Inc. | Parche transdérmico para la administración de 17-deacetil norgestimato, en combinación con un estrógeno. |
| JP4346696B2 (ja) * | 1996-05-28 | 2009-10-21 | 久光製薬株式会社 | 経皮治療用装置 |
| JP4167750B2 (ja) * | 1997-04-16 | 2008-10-22 | 久光製薬株式会社 | 経皮吸収用基剤及び該基剤を含有する経皮吸収製剤 |
| JP4399044B2 (ja) * | 1998-10-14 | 2010-01-13 | 久光製薬株式会社 | 吸収促進剤及び該吸収促進剤を有してなる経皮吸収製剤 |
| KR20010112479A (ko) * | 1999-07-01 | 2001-12-20 | 나까도미 히로다카 | 경피흡수 첩부제 |
| DE10053375C1 (de) * | 2000-10-27 | 2002-01-24 | Lohmann Therapie Syst Lts | Transdermale therapeutische Systeme mit lichtempfindlichen Wirkstoffen |
| TWI287455B (en) * | 2000-12-05 | 2007-10-01 | Noven Pharma | Crystallization inhibition of drugs in transdermal drug delivery systems and methods of use |
-
2004
- 2004-12-10 MX MXPA06006682A patent/MXPA06006682A/es active IP Right Grant
- 2004-12-10 BR BRPI0417530A patent/BRPI0417530B8/pt not_active IP Right Cessation
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- 2004-12-10 WO PCT/IB2004/052752 patent/WO2005058287A2/en active Application Filing
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- 2004-12-10 CN CN2004800413210A patent/CN1913878B/zh active Active
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- 2006-07-11 ZA ZA2006/05713A patent/ZA200605713B/en unknown
- 2006-07-11 EC EC2006006694A patent/ECSP066694A/es unknown
-
2010
- 2010-07-05 CU CU20100143A patent/CU23868B1/es active IP Right Grant
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0573133A1 (de) * | 1988-10-27 | 1993-12-08 | Schering Aktiengesellschaft | Mittel zur transdermalen Applikation das Gestoden enthält |
| US5512292A (en) * | 1990-10-29 | 1996-04-30 | Alza Corporation | Transdermal contraceptive formulations methods and devices |
| US5858394A (en) * | 1993-08-26 | 1999-01-12 | Schering Aktiengesellschaft | Agent for transdermal administration that contains gestodene esters |
| US5904931A (en) * | 1994-02-18 | 1999-05-18 | Schering Aktiengesellschaft | Transdermal therapeutic systems that contain sex steroids and dimethyl isosorbide |
| DE19906152B4 (de) * | 1999-02-10 | 2005-02-10 | Jenapharm Gmbh & Co. Kg | Wirkstoffhaltige Laminate für Transdermalsysteme |
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0417530B1 (pt) | 2018-01-23 |
| NO341989B1 (no) | 2018-03-12 |
| CA2549916A1 (en) | 2005-06-30 |
| AU2004298930B2 (en) | 2009-11-26 |
| IL176112A0 (en) | 2006-10-05 |
| IL176112A (en) | 2011-02-28 |
| CU23868B1 (es) | 2013-03-27 |
| CU20100143A7 (es) | 2011-10-31 |
| MXPA06006682A (es) | 2006-08-11 |
| CN1913878A (zh) | 2007-02-14 |
| ECSP066694A (es) | 2006-10-31 |
| NO20062594L (no) | 2006-07-10 |
| JP4965263B2 (ja) | 2012-07-04 |
| WO2005058287A3 (en) | 2006-03-02 |
| WO2005058287A2 (en) | 2005-06-30 |
| ZA200605713B (en) | 2008-01-08 |
| CA2549916C (en) | 2013-09-17 |
| AU2004298930A1 (en) | 2005-06-30 |
| EA200601089A1 (ru) | 2006-12-29 |
| BRPI0417530A (pt) | 2007-03-13 |
| KR20060128910A (ko) | 2006-12-14 |
| JP2007513938A (ja) | 2007-05-31 |
| NZ548091A (en) | 2009-12-24 |
| KR101168449B1 (ko) | 2012-07-25 |
| BRPI0417530B8 (pt) | 2021-05-25 |
| EA011160B1 (ru) | 2009-02-27 |
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