CN1883422B - 具有可逆连接机构的可植入的医疗装置和方法 - Google Patents

具有可逆连接机构的可植入的医疗装置和方法 Download PDF

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CN1883422B
CN1883422B CN2006100931564A CN200610093156A CN1883422B CN 1883422 B CN1883422 B CN 1883422B CN 2006100931564 A CN2006100931564 A CN 2006100931564A CN 200610093156 A CN200610093156 A CN 200610093156A CN 1883422 B CN1883422 B CN 1883422B
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乔舒阿·尤思
兰德尔·T·拜拉姆
肖恩·P·康伦
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Ethicon Endo Surgery Inc
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Abstract

一种用于可手术植入的医疗装置的连接机构，它包括一个或多个紧固件，所述紧固件可通过一体形成的致动器的操作同时从回缩位置运动到展开位置。连接机构可被构造成能够退动，并且紧固件同时从展开位置运动到回缩位置，从而允许去除或者重新定位医疗装置。一种施放器，它包括用于可拆卸地保持可植入的医疗装置的定位器，用于将其定位在所需位置并致动连接机构。该施放器被构造成能回缩连接机构，可植入的医疗装置可与身体组织分离。

Description

具有可逆连接机构的可植入的医疗装置和方法
技术领域
本发明总的涉及医疗植入物及其施放器，更具体地说，本发明涉及一种与各种医疗植入物一起使用的连接机构以及用于将所述医疗植入物与身体组织连接的施放器。本发明以下的描述与可手术植入的注射端口和其施放器有关，但本发明并不限于此。
背景技术
通常将可植入的医疗装置植入患者体内，以起到对患者的治疗作用。这种装置的非限制性例子包括起搏器、脉管进入端口、注射端口(例如与胃束带一起使用)以及胃起博装置。通常需要将这种植入物连接在皮下合适的位置，以便适当地发挥作用。人们期望植入所述装置的手术快速、便捷而且有效。在许多情况下，如果外科医生能够快速、便捷并有效地去除或者重新定位装置，则是十分有益的。
发明内容
本发明包括一种用于快速且便捷地将医疗植入装置固定到身体组织中的连接机构。该连接机构可以是可逆的，从而允许快速且便捷地拆除可植入的医疗装置，以便进行重新定位或者取出。尽管可以使用标准的可从市场购买的器械来致动所述连接机构，本发明还包括施放器，该施放器用于将可植入的医疗装置定位在所需位置，并快速便捷地致动所述连接结构，以固定可植入的医疗装置。
本发明还涉及如下内容。
(1)一种可手术植入的装置，包括：
(a)用于执行治疗功能的医疗植入物；
(b)连接机构，包括用于将所述植入物连接到身体上的与所述植入物成一整体的至少一个紧固件，所述紧固件具有一展开位置和一回缩位置；以及
(c)用于使所述紧固件从所述回缩位置运动到所述展开位置并返回到所述回缩位置的机构。
(2)一种可手术植入的装置，包括：
(a)用于执行治疗功能的医疗植入物；
(b)连接机构，包括用于将所述植入物连接到身体上的至少一个与所述植入物成一整体的紧固件，所述紧固件具有一展开位置和一回缩位置；以及
(c)致动器，其能够使所述至少一个紧固件从所述回缩位置运动到所述展开位置并返回到所述回缩位置。
(3)如第(2)项所述的装置，其中，所述致动器被构造成当所述至少一个紧固件设置在所述展开位置时，抵抗施加到所述至少一个成一整体的紧固件上的回缩力。
(4)如第(3)项所述的装置，其中，所述回缩力是转动力。
(5)如第(2)项所述的装置，其中，所述至少一个紧固件的每一个被构造成当所述至少一个紧固件从所述回缩位置运动到所述展开位置时，其围绕相应的轴线转动。
(6)如第(5)项所述的装置，其中，所述致动器被构造成围绕相应的轴线转动，并且包括所述至少一个紧固件的每一个的相关表面，每个所述表面被构造成当所述致动器沿着展开方向转动时，将转动力施加到每个相关紧固件上，由此使所述至少一个紧固件的每一个从所述回缩位置运动到所述展开位置。
(7)如第(5)项所述的装置，其中，所述致动器被构造成当所述至少一个紧固件设置在所述展开位置时，抵抗被施加到所述至少一个紧固件上的回缩转动力转动。
(8)如第(7)项所述的装置，其中，所述连接机构包括一止动系统，该止动系统被构造成阻止所述致动器的意外转动。
(9)如第(5)项所述的装置，其中，所述致动器被构造成围绕相应的轴线转动，并且所述连接机构包括用于所述至少一个紧固件的每一个的相关构件，每个所述构件由所述致动器承载，所述至少一个紧固件的每一个及其相关构件的构造使得当所述致动器沿着回缩方向转动时，所述构件将转动力施加到每个相关紧固件上，由此使所述至少一个紧固件的每一个从所述展开位置运动到所述回缩位置。
(10)如第(9)项所述的装置，其中，所述至少一个紧固件的每一个及其相关构件的构造使得当所述致动器沿着展开方向转动时，所述构件不施加展开力。
(11)如第(2)项所述的装置，其中，所述致动器可转动。
(12)如第(11)项所述的装置，其中，所述致动器包括基本为环状的圈，该圈由所述植入物可转动地支承。
(13)如第(2)项所述的装置，其中，所述致动器被构造成由任何一个或多个标准手术器械操纵，以使所述至少一个紧固件运动。
(14)如第(2)项所述的装置，其中，所述至少一个紧固件的每一个包括一远侧尖端，该远侧尖端被构造成穿刺身体组织，所述至少一个紧固件的每一个设置在所述植入物的相关凹槽中，当所述至少一个紧固件位于所述回缩位置时，每个所述远侧尖端位于所述相关凹槽中。
(15)如第(14)项所述的装置，其中，当所述至少一个紧固件位于所述回缩位置时，所述至少一个紧固件完全位于所述相关凹槽中。
(16)如第(14)项所述的装置，其中，每个所述远侧尖端设置在相关凹槽中，当所述至少一个紧固件位于所述展开位置时，每个所述远侧尖端位于所述相关凹槽中。
(17)如第(2)项所述的装置，其中，所述至少一个紧固件的每一个包括一远侧尖端，该远侧尖端被构造成穿刺身体组织，所述至少一个紧固件的每一个设置在相关凹槽中，当所述至少一个紧固件位于所述展开位置时，每个所述远侧尖端位于所述相关凹槽中。
(18)一种手术植入用于执行治疗功能的医疗植入物的方法，所述方法包括：
(a)提供至少一个与所述医疗植入物成一整体的紧固件；
(b)将所述医疗植入物设置在靠近身体组织的第一位置；以及
(c)使所述至少一个紧固件从回缩位置运动到展开位置，由此将所述医疗植入物在所述第一位置处连接到所述身体组织上。
(19)如第(18)项所述的方法，还包括使所述至少一个紧固件从所述展开位置运动到所述回缩位置的步骤，由此使所述医疗植入物与所述身体组织分离。
(20)如第(19)项所述的方法，进一步包括下列步骤：
(a)将所述医疗植入物设置在靠近身体组织的第二位置，以及
(b)使所述至少一个紧固件从所述回缩位置运动到所述展开位置，由此将医疗植入物在所述第二位置处连接到所述身体组织上。
附图说明
包含于说明书中并构成说明书的一部分的附图示例性的示出了本发明的实施例，并与上面给出的本发明的概述以及下面给出的实施例的详细描述一起用于解释本发明的原理。
图1是具有根据本发明构造的连接机构的注射端口的透视图。
图2是图1的注射端口的俯视图。
图3是图1的注射端口的仰视图。
图4是沿图3的线4-4截取的图1的注射端口的剖视图。
图5是图1的注射端口的分解透视图。
图6是图1的注射端口的底部的透视图，显示出处于缩回位置的连接机构。
图7是与图6类似的图1的注射端口的底部的透视图，显示出处于伸出/击发位置的连接机构。
图8是部分切去的局部侧面剖视图，显示出处于缩回位置的连接机构的紧固件。
图9是与图8类似的部分切去的局部侧面剖视图，显示出由致动环朝伸出/击发位置推进了的连接机构的紧固件。
图10是与图8类似的部分切去的局部侧面剖视图，显示出处于伸出/击发位置的连接机构的紧固件。
图11是与图8类似的部分切去的局部侧面剖视图，显示出由致动环朝缩回位置推进了的连接机构的紧固件。
图12是图1的注射端口的俯视图，其中省略了致动环，以显示出当紧固件处于缩回位置时连接件的位置。
图13是图1的注射端口的俯视图，其中省略了致动环，以显示出当紧固件处于伸出/击发位置时连接件的位置。
图14是处于缩回位置的图1的连接机构的视觉位置指示器和致动环止动系统的局部放大俯视图。
图15是处于伸出/击发位置的图1的连接机构的视觉位置指示器和致动环止动系统的局部放大俯视图。
图16是图1的注射端口的配合与锁定连接器的局部放大的分解透视图。
图17是锁定连接器的局部放大剖视图，该锁定连接器装配成与隔片保持器配合，但没有锁定在适当的位置。
图18是与图17类似的局部放大剖视图，显示出锁定在适当位置处的锁定连接器。
图19是安全盖的放大透视图。
图20是被构造成用于植入图1的注射端口的施放器的透视图。
图21是图20的施放器的分解透视图。
图22是图20的施放器的侧视图，其带有两个主体半部中的一个，以显示出处于未施放、非致动位置的内部元件。
图23是与图22类似的图20的施放器的侧视图，显示出处于施放、致动位置的内部元件。
图24是用于转动图20的施放器的凸轮机构的线状件的局部放大侧视图。
图25是图20的施放器的定位器的放大俯视透视图。
图26是图20的施放器的定位器和端口致动器的放大仰视透视图。
图27是图20的施放器的定位器的部分切去的端视图。
图28是图1的注射端口的放大剖视图，其由图20的施放器的定位器保持。
图29是图1的注射端口的放大剖视图，其在施放器已经被致动以将施放器致动器转动到展开位置后，设置在图20的施放器的定位器中。
现在将参照本发明的优选实施例对附图中示出的例子进行详细描述。
具体实施方式
在下列描述中，在所有附图中，相同的附图标记表示相同或者相应的部件。另外，在下列描述中，应理解，例如前、后、内部、外部以及类似术语是为了描述方便的词语，而不应解释为限制性术语。在该专利中的术语不是意味着用于限制在这个范围，而是可以其它的方位连接或者利用这里所描述的装置或者其部分。现在将更详细地参照附图对本发明的实施例进行描述。
参见图1-5，显示了一种可植入的医疗装置，更具体地说显示出了一种注射端口，其总的用2表示，包含根据本发明构造的连接机构。尽管在附图中显示的连接机构配备有注射端口2，所述连接机构可以与适于使用的任何可植入的医疗装置联用，包括仅仅作为例子的起搏器、脉管进入端口、注射端口(例如与胃束带一起使用)以及胃起博装置。
注射端口2包括隔片保持器4、隔片6和端口主体8。具有一体地构造的连接机构的注射端口2还包括一个或多个紧固件10、致动器12和多个连接构件14。
如图4所示，可由任何生物相容性材料(例如硅氧烷)制成的隔片6部分设置在隔片保持器4的内腔16中，位于环形平面18附近。隔片保持器4、端端口主体8和致动器12可由具有足够的硬度和强度的任何合适的生物相容性材料制成，例如聚醚醚酮(称为PEEK)。紧固件10和连接构件14可由任何合适的生物相容性材料(例如不锈钢)制成。
端口主体8包括环形边缘20，其围绕环形部分与隔片6的上表面接合。通过多个销22将端口主体8定位在隔片保持器4上，所述销22通过在端口主体8中的凹槽24a中形成的各个孔24设置，并且向内延伸到围绕隔片保持器4的底部周边形成的各个凹槽26中。销22可由任何合适的生物相容性材料(例如不锈钢)制成。
隔片6的未压缩高度环绕外径大约为5mm，未压缩直径大约为18mm。用于进入储存器20的暴露直径大约为14mm。环形边缘20的下表面和环形平面18之间的距离大约为4mm，使得隔片6被压缩大约20％，以足够自恢复，由此在压力下保持不透流体的系统，并且还允许较小尺寸。
板28设置在形成于隔片保持器4的底部的凹槽16a中，位于隔片6和流体室或者储存器30的下面。如图4所示，板28不与侧壁16b接触。在所示的实施例中，板28是金属的，例如不锈钢。当例如为了调节可调胃束带的尺寸通过隔片6插入针以从流体室30引入或者抽出流体时，金属板28将保护隔片保持器4不被刺破，并通过针为外科医生提供触觉反馈，显示针已经达到容器30的底部。可以任何合适的方式将板28固定到隔片保持器4上。在图示的实施例中，通过在板28的周边上延伸的保持凸缘4a将板28保持在适当的位置，最好见图4、28和29。最初，保持凸缘4a作为环形凸缘向上延伸，提供用于将板28插入到位于隔片保持器4的底部的间隙，然后止动凸缘4a卷起或者以其它方式变形，以至少一部分位于板28上方，由此保持板28。在图示的实施例中，凹槽16a的直径比侧壁16b的直径小，从而提供了形成环形凸缘以及使其变形为保持凸缘4a的空间。板28可以插入模制，其中保持凸缘4a如所示的模制。
隔片保持器4包括与流体室30流体连通的通道32，其由从保持器4底部附近的周边伸出的配件34限定。在实施例中所示的通向可调节胃束带(未显示)的管36与配件34连接，从而通过连接器40压靠在环形肋38上，所述连接器40围绕管36设置，并如下所述地固定到端口主体8上。套管42围绕管36设置，并且通过环形肋44固定到连接器40上。套管42释放管36上的张力，从而防止侧向加载时管36扭折。
将致动器12固定到端口主体8上。尽管在图示的实施例中，致动器12显示为由端口主体8可转动地支撑的环形圈，致动器12还可以是任何合适的构造，并可以任何合适的方式支撑，以允许致动器12用于使紧固件10在展开和回缩位置之间运动，并包括展开和回缩位置。如图5所示，端口主体8包括多个向下并向外伸出的小突起46。在图示的实施例中，有四个等间隔的小突起46。致动器12包括数量相等的相应凹槽48，每个凹槽48具有弓形底部50。为了将致动器12装配到端口主体8上，将凹槽48与小突起46对准，并向下推动凹槽，使小突起46临时向内偏转，直到小突起46到达凹槽48并向外运动，以使下边缘46a位于凹槽48中，从而保持致动器。如下所述，小突起46的长度和凹槽48的深度允许在致动器12和端口主体8之间存在一些轴向端部间隙。
致动器12通常可围绕端口主体8的中心轴线转动。在图示的实施例中，致动器12可转动大约40度的角度，但是可使用任何合适的角度。在图示的实施例中，当致动器12沿着展开方向转动使得紧固件10移动到展开位置时，由与小突起46接触的端部48c限制致动器12转动超出完全展开位置。
由从每个凹槽48的壁伸出的一对间隔设置的凸出止动肋48a、48b和从小突起46向外伸出的相应凸出肋46b形成止动系统。如下所述，在振动或者意外加载的情况下，止动系统有助于防止致动器12转动，以及防止紧固件10运动成动脱离完全缩回或者完全伸出击发的状态。
致动器12包括多个间隔设置的开口或者狭槽54，其可通过任何合适的器械接合，以将必要的扭矩传递给致动器12，由此使紧固件10延伸到致动位置。狭槽54被构造成由可从市场上购买的在所示的实施例中为矩形的器械接合，或者由下面描述的专用施放器来接合。端口主体8包括多个围绕其下部周边设置的凹槽56，所述凹槽56被构造成与如下所述的专用施放器配合。
还可参见图6及7，隔片保持器4包括多个定位小突起58，其从邻近的隔片保持器4的底部周边向外伸出。定位小突起58a可与配件34形成一体。小突起58和58a定位在形成于端口主体8的内表面中的各自具有互补形状的凹狭槽60中，从而将隔片保持器4与端口主体8正确对准。
图6示例性示出了位于缩回位置的紧固件10。如可看出的一样，紧固件10设置在形成于端口主体8中的相应的凹槽或者狭槽62中。图7示例性示出了处于伸出或者击发位置的紧固件10，其从狭槽62中伸出。致动器12的转动使紧固件10从缩回位置运动到伸出位置。
图8-11是示例性示出致动器12以及多个紧固件10中的一个的操作的一系列视图，应理解，对一个紧固件10的操作可以与对所有紧固件10的操作相同，在一个实施例中，它们可以同时从展开位置移动到回缩位置。图8显示出处于完全缩回状态、回缩位置的紧固件10，其完全设置于槽62内，使尖端64不暴露出来。这防止了尖端64意外刺到外科医生或者穿刺到任何物体。致动器12图示为逆时针转动到了凹槽48和小突起46允许的位置。在该位置，肋46b设置在肋48b的顺时针方向，如图14所示。连接构件14的第一端部14a由致动器12可转动地支承，分隔在与紧固件10的位置对应的位置。第二端部14b设置在紧固件10的开口66中。
为了致动连接机构，一体的致动器12沿着展开方向转动，在所示的一个实施例中为顺时针方向(可采用被构造成致动连接机构的任何合适的方向)，并且肋46b通过肋48b，使外科医生产生触觉信号外，还产生听觉信号。当将使紧固件10转动到伸出位置的作用力通过紧固件10的凸轮表面68和致动器12的致动凸轮表面70之间的相互作用传递给紧固件10时，连接构件14的第二端部14b在致动过程中在狭槽66中自由运动。当致动器12顺时针转动时，致动凸轮表面70接合凸轮表面68并推压在凸轮表面68上，从而使紧固件10围绕枢轴销22转动。来自致动凸轮表面70的力大部分相对于枢轴销22离心地相切地作用在凸轮表面68上，从而使紧固件10转动。在致动过程中，连接构件14的端部14b保持在狭槽66中自由运动，而不施加驱动力使紧固件10转动。
在图9中，由于致动器12顺时针转动，紧固件10转动了其整个转动范围的大约一半，大约90度。当致动器12顺时针转动时，致动器凸轮表面70和凸轮表面68之间的作用力使得致动器12如由组成元件的容许量所允许地略微向上运动。当致动器12进一步从图9所示的位置顺时针转动时，致动器凸轮表面70继续接合凸轮表面68并且推压在凸轮表面68上，从而使紧固件10进一步逆时针转动。
在图10中，致动器12顺时针转动到其最大程度，其中肋46b已经被推动经过止动肋48a(参见图15)。在该位置，紧固件10已经转动到其最大程度，在所示的实施例中几乎是180度，其中尖端64位于凹槽62中。在该位置，致动器凸轮表面70越过中心，致动器12可抵抗被施加到紧固件10上的回缩力向后驱动，因为凸轮表面68作用在致动器凸轮表面70上的方向倾向于将致动器12向上推动而不是使致动器12转动。紧固件10的远端部分基本上被构造成一个梁，图示为沿着其长度具有通常为矩形的横截面，并且朝着其尖端64逐渐变细。在紧固件10延伸180度处于完全伸出状态的展开位置的情况下，可能作用在紧固件10上的力倾向于通过由枢轴销22限定的枢轴作用，而不是使紧固件10转动。应注意的是，尽管示例的销22为与紧固件10分离的件，但是这两个部件可形成一体或者甚至是一件式整体构造。
如果需要缩回紧固件10，以例如去除或者重新定位植入的装置，可以使致动器12沿着回缩方向转动，在一个图示的实施例中为逆时针方向。从图10所示的致动器12的位置开始，致动器12可逆时针转动，其中致动器凸轮表面70在凸轮表面68上滑动，而不会使紧固件10转动。在所示的实施例中，致动器12继续逆时针转动使得凸轮表面70运动成与凸轮表面68脱离接触，而基本上没有转动力施加到紧固件10上，直到连接构件的第二端部14b到达狭槽66中的一个位置，例如狭槽66的一个端部，在此处连接构件14开始在狭槽66上进行拖拉，从而使紧固件10转动并开始缩回。
如图11所示，与图10中显示的位置相比，致动器12已经逆时针行进，并且紧固件10转动了其全部范围的大约一半。将图9与图11相比可以看出，致动器12位于不同的位置，而紧固件10位于相同的位置，与连接机构是否被致动或者被退动(缩回)无关。这种情况与致动器凸轮表面70直接推压在凸轮表面68上相比，是由于当连接构件14在狭槽66上拉动时产生空转。为了使紧固件10完全缩回，使致动器12转动，直到止动肋46b经过止动肋48b而关合。
参照图8，当紧固件10到达全部回缩的位置时，尖端64可完全位于狭槽或者凹槽62中。通过紧固件10防止连接构件14进一步运动，从而连接构件14防止致动器12进一步回缩转动。
参见图2和3，致动器12包括穿过其中形成的开口52a，当致动器位于回缩位置时，开口52a与形成在端口主体8中的相应开口52b对准。如果不采用一体的连接结构，外科医生可用开口52a和52b来缝合注射端口2。
参见图12和13，显示了连接机构，没有致动器12。所示的连接构件14位于其相应的实际位置，此时第一端部14a由致动器12支撑，处于展开和回缩状态。
参见图14和15，俯视地示出了包含在注射端口2中的连接机构的视觉位置指示器和致动器环止动系统的一部分。在图14中，连接机构处于缩回的回缩状态或位置。在该位置，止动肋46b位于止动肋48b的顺时针方向，并因此处于回缩的止动位置。在图15中，连接机构处于致动或者展开位置。在该位置，止动肋46b位于止动肋48a的逆时针方向，并因此处于展开的止动位置。
图14和15示例性地示出了连接机构状态的视觉指示器，如图14所示，可利用标记，例如与致动器环12整体成型的未锁定的锁形图标72和锁闭的锁形图标74。可采用任何合适的图形指示器，并可以打印或者以其它合适的方式应用。端口主体8可包括指示器76，以提供用于可动标记的参考点。可包括有箭头78，以指示致动器12的双向运动。
图16-18示例性地示出了连接器40和端口主体8之间的锁定连接。图16是分解透视图，显示出了部分被伸出部78围绕的配件34。图17显示出了伸出部78的横截面，其中连接器40大体上围绕配件34设置，并且管36与伸出部78的周边狭槽78c对准。连接器40包括一对从其上向外伸出的小突起40a、40b。为了组装，沿着管36和配件34引导连接器40，其中小突起40a、40b与伸出部78的开口78a和78b对准。在小突起40a、40b与周边狭槽78c对准的情况下，转动连接器40以将其锁定在适当的位置。在转动过程中，止动边缘78d形成反对小突起40a转动的干扰，但止动边缘78d的大小被设定成允许小突起40a转过而到达图18所示的锁定位置。
图19显示了安全盖80，其可以被可转动地固定到注射端口2的底部上，以覆盖紧固件10，从而保护用户在处理注射端口2时不会偶然暴露给锋利的尖端64。安全盖80包括主体82，其中环形边缘84的和凸起的中心86限定了环形凹槽8的。可通过任何合适的构造将安全盖80定位并保持到注射端口上。如图所示，主体82包括多个弓形保持突起90，它们从凸出的中心86向上伸出。如图3、6和7中最好地示出的一样，弓形保持突起90的形状被设定成与相应的弓形狭槽92互补，并可具有如图所示的肋。通过将弓形保持突起90插入到弓形狭槽92中而将安全盖80固定到注射端口2上，所述弓形狭槽92的大小被设定成适于保持突起90。紧固件10由此与环形凹槽88对准，所述环形凹槽88的大小允许紧固件10伸出而不会与安全盖80接触。如图所示，由于弓形保持突起90和弓形狭槽92分别具有相同的尺寸和相等的间隔，所以没有将安全盖80标引到特定位置，并且可以在四个不同的位置将安全盖80固定到注射端口2上。安全盖80包括具有多个凸出的肋96的牵引突起94，以提供更好的夹持表面。尽管可沿着任何合适的方位对牵引突起94进行定向，但是在该实施例中，牵引突起94和弓形保持突起90之间的相对位置使牵引突起定位成与连接器40的方向成45度角。突起90和狭槽92可具有任何合适的形状。
如前所述，可以通过将狭槽54与从市场上购买的器械接合或者通过专用施放器来致动连接机构。图20显示了施放器，总的用100表示，其被构造成定位、致动、退动、去除或者重新定位注射端口2。应当注意的是，作为本发明的应用于施放器的方面的实践不限于这里所示的特定施放器。
如图20所示，施放器100包括主体102、定位器104、致动器106和安全开关108。如下所述，可将注射端口2组装到定位器104上，其中伸出部78和突起96设置在对准狭槽110和112中。定位器104相对于主体102成一角度，从而允许在植入期间能对注射端口2进行更容易以及更好的观察。在图示的实施例中，所述角度为20度，并且主体102的轴部分为10cm。
参见图21，主体102包括第一和第二半部102a和102b，它们彼此组装以容纳内部元件。除了定位销202、枢轴销114和鱼鳞板以外，主体半部102a和102b彼此基本上相同。图示为从主体半部102a伸出的定位销202与主体半部102b上具有相应的互补形状的开口(未显示)配合。在开口中多个定位销202的接合足以将主体半部102a和102b保持在一起。可选择的是，销202可从主体半部102b伸出，而主体半部102a带有开口。可采用任何合适的构造来将主体半部102a和102b组装和固定在一起。
致动器106包括第一和第二半部106a和106b。图示为从致动器半部106a伸出的定位销204与致动器半部106b上具有相应的互补形状的开口(未显示)配合。可选择的是，销204可从致动器半部106b伸出，而致动器半部106a带有开口。可采用任何合适的构造来将致动器半部106a和106b组装和固定在一起。主体半部102b包括枢轴销114b，该枢轴销114b在一端可转动地支撑致动器106，穿过孔116a和116b延伸进入开口114a中。主体半部102a包括枢轴销118b(参见图22)，枢轴销118b可转动地支撑安全开关108。主体半部102a和102b、定位器104、致动器半部106a和106b以及安全开关108可由任何生物相容性材料(例如聚碳酸酯)制成。
参见图21-24，施放器100包括凸轮120、具有挠性轴124的驱动轴122、驱动轴销126、凸轮回复弹簧128、安全偏动弹簧130以及致动器132。致动器132被构造成执行医疗植入物的连接机构的放置和收回。凸轮120包括轴134和凸轮卡圈136。轴134的上端具有“T”形构造，终止于横向构件138中。凸轮卡圈136限定了一个中空的内部和一对间隔设置的具有互补形状的凸轮轨道140a和140b，所述凸轮轨道140a和140b形成在凸轮卡圈136的相对的两侧。驱动轴122的上端122a部分设置于由凸轮卡圈136限定的中空内部中，由驱动轴销126捕获于其中。驱动轴销126的大小被设置成使每一端部位于相应的凸轮轨道140a、140b中。中空内部的长度使上端122a可在其中往复运动，其中凸轮轨道140a、140b在往复运动过程中通过驱动轴销126将转动赋予驱动轴122。凸轮120、驱动轴122和致动器132可由具有足够硬度和强度的任何合适的材料制成。在图示的实施例中，凸轮120和致动器132由液晶聚合物(例如Vectratm LCP)制成，并且驱动轴122由PPE+PS(例如Noryltm)制成。驱动轴销126和凸轮回复弹簧128可由任何合适的材料(例如不锈钢)制成。
凸轮120保持在主体部分102a和102b之间，并且在一个实施例中，例如图示的可往复运动。凸轮卡圈136具有间隔设置的通常为平坦的外表面142a和142b，通过这些表明形成轨道140a和140b。这些表面142a和142b设置于在主体部分102a和102b中形成的导向壁144a和144b之间。凸轮卡圈136还包括相对朝向的通道146a和146b(参见图23)，它们通过分别在主体部分102a和102b中形成的导向件148a和148b(未显示)引导，用于往复运动。轴134的上端和横向构件138夹设在致动器半部106a和106b之间。每个致动器半部106a、106b包括由一对从致动器半部106a和106b的内表面伸出的间隔设置的壁150a和150b限定的凸轮轨道150。当致动器106围绕销114转动时，凸轮轨道150被构造成收纳并引导横向构件138，从而迫使凸轮120向下线性行进到主体102中。
驱动轴122包括环形卡圈152，其收纳于分别在主体半部102a和102b中形成的狭槽154a和154b(未显示)中。狭槽154a和154b可转动地支撑驱动轴122。驱动轴122和凸轮120通常彼此对准并在同一直线上，从而限定了主体102的轴部分的轴线。当凸轮102向下行进时，驱动轴销126跟随凸轮轨道140a和140b运动，从而使驱动轴122转动，由此将线性运动转化成旋转运动。凸轮回复弹簧128提供作用在凸轮卡圈136上的名义回复力。
挠性轴124由在每个主体半部102a、102b中形成的多个肋156支撑，肋156支撑挠性轴124的弯曲，该挠性轴允许将转动运动传递到相对于主体102的轴成一角度设置的致动器132。挠性轴124可由任何合适的生物相容性材料(例如不锈钢)制成。在图示的实施例中，挠性轴124具有绞合结构，其中央芯具有围绕其缠绕的多层线。可以足以限制转动端部间隙以防止或者最小化空转的任何合适的方式将挠性轴124的端部124a和124b分别连接到端部122b和致动器132上。在图示的实施例中，端部124a超压成型(overmold)于端部122b中，并且端部124b压配合于致动器132中。可选择的是，可将端部124a压配合于端部122b中，并且将端部124b超压成型于致动器132中，也可以都压配合，或者都超压成型(相应地改变定位器104的构造以允许组装)。
参见图21-25，致动器132包括盘状构件158和从盘状构件158向上伸出的轴160。轴160的上端包括一对向上伸出的突起162a和162b。定位器104包括限定了在其中穿过的孔166的轴毂164。孔164的形状能收纳并可转动地支撑轴160，并包括两个向上延伸的弓形凹槽168a和168b，所述凹槽被构造成为突起162a和162b提供装配间隙，从而能够使轴毂164能插入孔166中。轴160和轴毂164的长度的尺寸被设定设置成使突起162a和162b位于轴毂164的上表面164a的上方，从而在将其相对于轴毂164轴向地保持的同时允许致动器132转动。止动件170a和170b从上表面164a向上伸出，限制致动器132的转动。孔166限定了定位器104的中心轴线，致动器132围绕该轴线转动。如前所述，将定位器104的中心轴线设置程相对于与主体102的轴部分的轴线成一角度。
轴毂164包括一对相对地伸出的突起172a和172b，它们将端口致动器104保持在主体102上并防止转动。主体半部102a和102b包括相应的凹槽174a(参见图21)和174b(未示出)，所述凹槽的形状与突起172a和172b的形状互补。
再参见图26和27，可看出致动器132的盘状构件158设置在定位器104中。致动器132包括一对间隔设置的柱176a和176b，它们从构件158的邻近周边158a伸出。柱176a和176b具有与开口54互补的形状。在图示的实施例中，柱176a和176b的远端逐渐变细，以有助于将柱176a和176b引导到开口54中。可采用任何合适的构造来在致动器132和致动器12之间形成能够使致动器12致动的可释放的接触。
盘状构件158还包括一对间隔设置的凸轮178a和178b，它们从构件158的周边158a向外并向上伸出。图27示例地示出了凸轮178a的沿着元件158的底面附近截取的横截面。凸轮178a和178b包括斜坡180a和180b，它们分别从周边158a开始并分别通向表面182a和182b。每个表面182a、182b都是弓形的，在图示的实施例中显示为通常具有恒定的半径。
在图示的实施例中，定位器104包括一对间隔设置的悬臂184a和184b，每个悬臂分别具有肋186a和186b。为了清楚起见，图27显示了通过肋186a截取的臂184a横截面，该横截面与用于凸轮178a的横截面处于同一水平面在。在臂184a和184b的远端，臂184a和184b分别包括向内延伸的凸缘188a和188b。凸缘188a和188b具有与端口主体8上的凹槽56互补的形状，凸缘188a和188b被构造成当注射端口2由定位器104保持时与凸缘56a接合。
在图示的实施例中，在非致动状态，柱176a和176b通常分别与184a和184b对准，但是柱176a和176b可处于与致动器12的致动结构的位置相对应的任何位置，所述致动结构在图示的实施例中为开口54。当按压致动器106时，致动器132转动(在图示的实施例中，当从底部观察时为逆时针方向)，使凸轮178a和178b行进，从而斜坡180a和180b分别与肋186a和186b接触，由此使184a和184b向外偏转。当表面182a和182b与肋186a和186b接合时，184a和184b偏转的距离足以使凸缘188a和188b运动到它们不再伸进凹槽56中或者与凸缘56a接触的位置，从而从定位器104释放注射端口2。
图28示例性地示出了设置于定位器104中并由其保持的注射端口2，其中伸出部外壳78和突起96分别设置在狭槽110和112中(见图20，在图28中未显示)。如图所示，柱176a和176b伸进致动器12的开口54中，并且凸缘188a和188b伸进靠近凸缘56a的凹槽56中。当将注射端口12插入定位器104中时，安全盖80与注射端口12连接，从而盖紧固件10(在图28中未显示)。
还可参见图20和22，为了将注射端口2插入到定位器104中，沿着回缩位置定向致动器106，从而使致动器132处于回缩位置。致动器12沿着回缩位置定向，并被插入致动器104中，并且伸出部外壳78和突起96分别设置在槽110和112中。
如图20所示，致动器106可包括视觉指示器(例如未锁定的锁形图标190)和标记(例如锁定的锁形图标192)，所述视觉指示器用于指示致动器106是否完全处于回缩状态，所述标记用于指示致动器106是否处于展开状态。可通过任何合适的方式包含所述视觉指示，例如通过与致动器106整体成型、作为粘附膜应用或者类似方式，或者直接打印在致动器106上。在图示的指示器中，未锁定的锁形图标190在主体102的上边缘附近可见，但是也可采用其它构造的指示，例如在主体102中形成的窗口等，用于显示标记。
为了使用，如果需要，由外科医生通过切口将定位器104和一部分主体102插入，并且将其定位在身体组织附近的所需位置，医疗植入物(在图示的实施例中显示为注射端口2)与身体组织连接。定位器104和主体102之间的角度允许外科医生直接观察手术部位。由于注射端口处于适当的位置，沿着环形路径将一个或多个紧固件10从回缩位置移动到展开位置，以接合组织。紧固件10允许注射端口2固定到组织上，其中保持强度等于或者大于用缝线缝合时的保持强度。安全开关108围绕枢轴销118转动，由此将锁定突起194从下部开口196中退出，从而允许致动器106围绕枢轴销114转动。这种作用使凸轮轨道150将横向构件138向下移动，由此使凸轮卡圈136转动驱动轴122，从而相对于定位器104转动致动器132。
致动器132的转动通过使致动器12转动而使致动器12致动。伸出部78和突起96分别与槽110和112之间的接合防止了端口主体8转动，从而允许致动器12和端口主体8之间可进行相对运动。
一旦致动器106到达展开位置，锁定突起194被推进上部开口198中，从而将致动器106保持在展开位置。在图示的实施例中，当锁定突起194合入上部开口198中时，弹簧130将锁定突起194偏压成到足以产生声音，从而提供了致动器106完全展开的听觉信号，并由此提供了致动器12和紧固件10完全展开的听觉信号。如图29所示，由于致动器106处于展开位置，致动器12已经转动，并且紧固件10处于已经穿刺身体组织(例如直肌外皮)的展开位置。凸轮178a和178b已经转动到表面182a和182b靠近肋186a和186b的位置，其中臂184a个184b向外偏转，从而凸缘188a和188b不位于凹槽56中，并且不与凸缘56a接合。由于注射端口2固定到身体组织上，并且从定位器104释放，外科医生可退回定位器104，将注射端口2留在适当的位置。如果连接机构的状态的视觉指示器包括于植入物中，则外科医生可知道连接机构是否完全展开。
包含于注射端口2中的连接机构被构造成可逆的，从而可以移动医疗植入物、注射端口2，以例如对其重新定位或者将其从患者体内去除。为了做到这一点，当致动器106处于展开位置时，定位器104被放置到注射端口2上方，将伸出部78和突起96定位在槽110和112中，从而使柱176a和176b与凹槽54接合。使安全开关108转动，以从上部开口198中退回锁定突起194，同时外科医生拉动致动器106的伸出部200。尽管凸轮回复弹簧128向上推压凸轮卡圈136，但是伸出部分200施加额外的回复力。当凸轮轨道150拉起横向构件138时，致动器132使致动器12转动，同时使紧固件10从展开位置运动到回缩位置，而凸轮178a和178b与肋186a和186b脱离接合，从而允许凸缘188a和188b与凹槽56和凸缘56a接合，以便将注射端口2保持在定位器104中。当致动器106已经移动到回缩位置时，锁定突起194合入下部开口196中，产生致动器106完全回缩的听觉信号，并且注射端口2与身体组织分离，并且注射端口2可被重新定位或者被去除。
总的说来，已经描述了通过采用本发明的构思产生的许多好处。出于示例和描述的目的，已经对本发明的一个或多个实施例进行了前述描述。并不意味着这些描述是穷尽性的也不意味着将本发明限制为所公开的精确形式。根据上述启示可进行修改和变化。所选择和描述的一个或多个实施例是为了解释本发明的原理，因而当适于预期的特定使用时，其实际应用使本领域普通技术人员能够以各种实施方式和各种修改方案应用本发明。本发明的范围由后附权利要求限定。

Claims (7)

1.一种可手术植入的装置，包括：
(a)用于执行治疗功能的医疗植入物，所述医疗植入物具有针可穿刺的隔片以及流体储存器；
(b)连接机构，包括用于将所述医疗植入物连接到身体组织上的与所述医疗植入物成一整体的至少两个紧固件，所述至少两个紧固件具有一展开位置和一回缩位置；以及
(c)致动器，所述致动器可操作地使所述至少两个紧固件从所述回缩位置运动到所述展开位置并返回到所述回缩位置，其中所述致动器包括与所述医疗植入物成一整体的一个或多个凸轮表面，当所述至少两个紧固件处于所述回缩位置时所述一个或多个凸轮表面初始地与所述至少两个紧固件分开，所述一个或多个凸轮表面能够沿着第一平面转动运动成与所述至少两个紧固件接触，其中当所述致动器沿着第一转动方向转动时所述一个或多个凸轮表面沿着第一转动方向转动，所述一个或多个凸轮表面被构造成与所述至少两个紧固件接合并推动所述至少两个紧固件以使得所述至少两个紧固件运动至所述展开位置，其中所述至少两个紧固件沿着一个或多个平面运动以达到所述展开位置，所述一个或多个平面与所述第一平面不共面，当所述致动器沿着与所述第一转动方向相反的第二转动方向转动时，所述致动器可操作地将所述至少两个紧固件从所述展开位置拉到所述缩回位置。
2.一种可手术植入的装置，包括：
(a)用于执行治疗功能的医疗植入物，所述医疗植入物具有带底部周边的壳体，所述底部周边限定用于邻接组织放置的平坦表面和垂直于所述壳体的底部周边的中央轴线，所述医疗植入物还包括连接到所述壳体的针可穿刺的隔片以及由所述壳体和隔片围绕的流体储存器，所述中央轴线经过所述隔片和流体存储器；
(b)连接机构，包括用于将所述医疗植入物连接到患者的与所述医疗植入物成一整体的至少两个紧固件，所述至少两个紧固件具有一展开位置和一回缩位置，其中每个紧固件绕着相应的紧固件轴线沿着弓形路径运动，每个相应的紧固件轴线相对于中央轴线径向向外延伸；以及
(c)致动器，所述致动器能够绕着中央轴线转动而使所述至少两个紧固件从所述回缩位置运动到所述展开位置并返回到所述回缩位置，当所述致动器绕着所述中央轴线转动时，所述致动器沿着圆形方向平行于所述壳体的平坦表面运动，以与所述至少两个紧固件的每一个操作地接合，其中在所述致动器沿着第一转动方向转动时所述致动器可操作地将所述至少两个紧固件从所述缩回位置推动到所述展开位置，其中在所述致动器沿着第二转动方向转动时所述致动器可操作地将所述至少两个紧固件从所述展开位置拉到所述缩回位置。
3.如权利要求2所述的装置，其中，所述致动器被构造成当所述至少两个紧固件设置在所述展开位置时，抵抗施加到所述至少两个紧固件中的至少一个上的回缩力。
4.如权利要求3所述的装置，其中，所述回缩力是转动力。
5.如权利要求2所述的装置，其中，所述至少两个紧固件的每一个被构造成当所述至少两个紧固件从所述回缩位置运动到所述展开位置时，围绕相应的紧固件轴线转动，其中每个紧固件轴线垂直于所述中央轴线。
6.如权利要求5所述的装置，其中，所述致动器包括所述至少两个紧固件的每一个的相关表面，每个所述表面被构造成当所述致动器沿着展开方向转动时，将转动力施加到每个相关紧固件上，由此将所述至少两个紧固件的每一个从所述回缩位置推动到所述展开位置。
7.如权利要求5所述的装置，其中，所述致动器被构造成当所述至少两个紧固件设置在所述展开位置时，抵抗被施加到所述至少两个紧固件上的回缩转动力转动。
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US10/741,875 US7862546B2 (en) 2003-06-16 2003-12-19 Subcutaneous self attaching injection port with integral moveable retention members
US11/166,625 US8007474B2 (en) 2003-06-16 2005-06-24 Implantable medical device with reversible attachment mechanism and method
US11/166,598 US8029477B2 (en) 2003-12-19 2005-06-24 Applier with safety for implantable medical device
US11/166,283 US7553298B2 (en) 2003-12-19 2005-06-24 Implantable medical device with cover and method
US11/166,610 US7850660B2 (en) 2003-12-19 2005-06-24 Implantable medical device with simultaneous attachment mechanism and method
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US11/166,968 US7561916B2 (en) 2005-06-24 2005-06-24 Implantable medical device with indicator

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Families Citing this family (258)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8177762B2 (en) 1998-12-07 2012-05-15 C. R. Bard, Inc. Septum including at least one identifiable feature, access ports including same, and related methods
US7338433B2 (en) 2002-08-13 2008-03-04 Allergan, Inc. Remotely adjustable gastric banding method
EP2181655B1 (en) * 2002-08-28 2016-12-07 Apollo Endosurgery, Inc. Fatigue-restistant gastric banding device
US7850660B2 (en) * 2003-12-19 2010-12-14 Ethicon Endo-Surgery, Inc. Implantable medical device with simultaneous attachment mechanism and method
US8715243B2 (en) * 2003-06-16 2014-05-06 Ethicon Endo-Surgery, Inc. Injection port applier with downward force actuation
US7561916B2 (en) * 2005-06-24 2009-07-14 Ethicon Endo-Surgery, Inc. Implantable medical device with indicator
US7862546B2 (en) * 2003-06-16 2011-01-04 Ethicon Endo-Surgery, Inc. Subcutaneous self attaching injection port with integral moveable retention members
WO2005015476A2 (en) * 2003-08-07 2005-02-17 Hsb Solomon Associates, Llc System and method for determining equivalency factors for use in comparative performance analysis of industrial facilities
EP2311520B1 (en) 2003-09-15 2014-12-03 Apollo Endosurgery, Inc. Implantable device fastening system
US8162897B2 (en) * 2003-12-19 2012-04-24 Ethicon Endo-Surgery, Inc. Audible and tactile feedback
ES2399951T3 (es) 2004-01-23 2013-04-04 Allergan, Inc. Banda gástrica ajustable de una pieza que puede fijarse de forma liberable
ATE489897T1 (de) * 2004-01-23 2010-12-15 Allergan Inc Befestigungssystem für eine implantierbare vorrichtung und anwendungsverfahren
EP2145610A1 (en) 2004-03-08 2010-01-20 Allergan Medical S.A. Closure system for tubular organs
ES2368149T3 (es) 2004-03-18 2011-11-14 Allergan, Inc. Aparato para el ajuste del volumen de globos intragástricos.
WO2006049725A2 (en) 2004-03-23 2006-05-11 Minimus Surgical Systems Surgical systems and devices to enhance gastric restriction therapies
US7946976B2 (en) 2004-03-23 2011-05-24 Michael Gertner Methods and devices for the surgical creation of satiety and biofeedback pathways
US20050228415A1 (en) * 2004-03-23 2005-10-13 Michael Gertner Methods and devices for percutaneous, non-laparoscopic treatment of obesity
US7255675B2 (en) 2004-03-23 2007-08-14 Michael Gertner Devices and methods to treat a patient
US20060195139A1 (en) * 2004-03-23 2006-08-31 Michael Gertner Extragastric devices and methods for gastroplasty
US20050148956A1 (en) * 2004-06-01 2005-07-07 Conlon Sean P. Surgically implantable injection port having an improved fastener
US7955357B2 (en) 2004-07-02 2011-06-07 Ellipse Technologies, Inc. Expandable rod system to treat scoliosis and method of using the same
US7775966B2 (en) 2005-02-24 2010-08-17 Ethicon Endo-Surgery, Inc. Non-invasive pressure measurement in a fluid adjustable restrictive device
US20060173423A1 (en) * 2005-02-01 2006-08-03 Conlon Sean P Method for surgically implanting a fluid injection port
US8066629B2 (en) 2005-02-24 2011-11-29 Ethicon Endo-Surgery, Inc. Apparatus for adjustment and sensing of gastric band pressure
US7927270B2 (en) 2005-02-24 2011-04-19 Ethicon Endo-Surgery, Inc. External mechanical pressure sensor for gastric band pressure measurements
US7775215B2 (en) 2005-02-24 2010-08-17 Ethicon Endo-Surgery, Inc. System and method for determining implanted device positioning and obtaining pressure data
US7699770B2 (en) 2005-02-24 2010-04-20 Ethicon Endo-Surgery, Inc. Device for non-invasive measurement of fluid pressure in an adjustable restriction device
US7658196B2 (en) 2005-02-24 2010-02-09 Ethicon Endo-Surgery, Inc. System and method for determining implanted device orientation
US8016744B2 (en) 2005-02-24 2011-09-13 Ethicon Endo-Surgery, Inc. External pressure-based gastric band adjustment system and method
US7947022B2 (en) 2005-03-04 2011-05-24 C. R. Bard, Inc. Access port identification systems and methods
US8029482B2 (en) 2005-03-04 2011-10-04 C. R. Bard, Inc. Systems and methods for radiographically identifying an access port
US9474888B2 (en) 2005-03-04 2016-10-25 C. R. Bard, Inc. Implantable access port including a sandwiched radiopaque insert
EP1858565B1 (en) 2005-03-04 2021-08-11 C.R. Bard, Inc. Access port identification systems and methods
US8251888B2 (en) 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
US10307581B2 (en) 2005-04-27 2019-06-04 C. R. Bard, Inc. Reinforced septum for an implantable medical device
EP1874393B1 (en) 2005-04-27 2017-09-06 C.R.Bard, Inc. Infusion apparatuses
DE602006019587D1 (de) 2005-04-27 2011-02-24 Bard Inc C R Spritzenpumpesystem zur Injektion von Kontrastmittel in einer intravenösen Leitung
US7651483B2 (en) 2005-06-24 2010-01-26 Ethicon Endo-Surgery, Inc. Injection port
US7918844B2 (en) 2005-06-24 2011-04-05 Ethicon Endo-Surgery, Inc. Applier for implantable medical device
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
US7798954B2 (en) 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
KR20090003175A (ko) * 2006-01-17 2009-01-09 헤마푸레 아베 의료 용도를 위한 커플링 장치 및 그러한 커플링 장치를포함하는 액세스 시스템
CN101360530A (zh) * 2006-01-17 2009-02-04 赫马普里股份公司 用于医学目的的通路装置及其生产方法和包括该通路装置的通路系统
WO2007082333A1 (en) * 2006-01-18 2007-07-26 Kylie Annesley Lundqvist And Juanita Margaret Lundqvist As Trustees Of The Lundqvist Family Trust Attachment device and method
US9907943B2 (en) * 2006-02-09 2018-03-06 Deka Products Limited Partnership Infusion pump assembly
US8870742B2 (en) 2006-04-06 2014-10-28 Ethicon Endo-Surgery, Inc. GUI for an implantable restriction device and a data logger
US8152710B2 (en) 2006-04-06 2012-04-10 Ethicon Endo-Surgery, Inc. Physiological parameter analysis for an implantable restriction device and a data logger
US8070768B2 (en) 2006-04-19 2011-12-06 Vibrynt, Inc. Devices and methods for treatment of obesity
US7976554B2 (en) 2006-04-19 2011-07-12 Vibrynt, Inc. Devices, tools and methods for performing minimally invasive abdominal surgical procedures
US8556925B2 (en) 2007-10-11 2013-10-15 Vibrynt, Inc. Devices and methods for treatment of obesity
US8187297B2 (en) 2006-04-19 2012-05-29 Vibsynt, Inc. Devices and methods for treatment of obesity
US8342183B2 (en) 2006-04-19 2013-01-01 Vibrynt, Inc. Devices and methods for treatment of obesity
US7404543B2 (en) * 2006-09-12 2008-07-29 Victaulic Company Slow closing actuator and valve
US7862502B2 (en) 2006-10-20 2011-01-04 Ellipse Technologies, Inc. Method and apparatus for adjusting a gastrointestinal restriction device
US8246533B2 (en) 2006-10-20 2012-08-21 Ellipse Technologies, Inc. Implant system with resonant-driven actuator
US9265912B2 (en) 2006-11-08 2016-02-23 C. R. Bard, Inc. Indicia informative of characteristics of insertable medical devices
US9642986B2 (en) 2006-11-08 2017-05-09 C. R. Bard, Inc. Resource information key for an insertable medical device
WO2008085290A2 (en) 2006-12-28 2008-07-17 Vibrynt, Inc. Devices and methods for treatment of obesity
US7655004B2 (en) 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
US7815662B2 (en) 2007-03-08 2010-10-19 Ethicon Endo-Surgery, Inc. Surgical suture anchors and deployment device
US8075572B2 (en) 2007-04-26 2011-12-13 Ethicon Endo-Surgery, Inc. Surgical suturing apparatus
US8100922B2 (en) 2007-04-27 2012-01-24 Ethicon Endo-Surgery, Inc. Curved needle suturing tool
EP2164559B1 (en) 2007-06-20 2017-10-25 Medical Components, Inc. Venous access port with molded and/or radiopaque indicia
CN101678199B (zh) * 2007-06-22 2013-10-30 医疗器械公司 薄型静脉接入端口组件
US9610432B2 (en) 2007-07-19 2017-04-04 Innovative Medical Devices, Llc Venous access port assembly with X-ray discernable indicia
WO2009012385A1 (en) 2007-07-19 2009-01-22 Medical Components, Inc. Venous access port assembly with x-ray discernable indicia
US8262655B2 (en) 2007-11-21 2012-09-11 Ethicon Endo-Surgery, Inc. Bipolar forceps
US8568410B2 (en) 2007-08-31 2013-10-29 Ethicon Endo-Surgery, Inc. Electrical ablation surgical instruments
US8579897B2 (en) 2007-11-21 2013-11-12 Ethicon Endo-Surgery, Inc. Bipolar forceps
US20090112263A1 (en) 2007-10-30 2009-04-30 Scott Pool Skeletal manipulation system
US20090112059A1 (en) 2007-10-31 2009-04-30 Nobis Rudolph H Apparatus and methods for closing a gastrotomy
US8480657B2 (en) 2007-10-31 2013-07-09 Ethicon Endo-Surgery, Inc. Detachable distal overtube section and methods for forming a sealable opening in the wall of an organ
US9579496B2 (en) 2007-11-07 2017-02-28 C. R. Bard, Inc. Radiopaque and septum-based indicators for a multi-lumen implantable port
US8187163B2 (en) 2007-12-10 2012-05-29 Ethicon Endo-Surgery, Inc. Methods for implanting a gastric restriction device
US8100870B2 (en) 2007-12-14 2012-01-24 Ethicon Endo-Surgery, Inc. Adjustable height gastric restriction devices and methods
US8142452B2 (en) 2007-12-27 2012-03-27 Ethicon Endo-Surgery, Inc. Controlling pressure in adjustable restriction devices
US8377079B2 (en) 2007-12-27 2013-02-19 Ethicon Endo-Surgery, Inc. Constant force mechanisms for regulating restriction devices
US8591395B2 (en) 2008-01-28 2013-11-26 Ethicon Endo-Surgery, Inc. Gastric restriction device data handling devices and methods
US8192350B2 (en) 2008-01-28 2012-06-05 Ethicon Endo-Surgery, Inc. Methods and devices for measuring impedance in a gastric restriction system
US8337389B2 (en) 2008-01-28 2012-12-25 Ethicon Endo-Surgery, Inc. Methods and devices for diagnosing performance of a gastric restriction system
US9060771B2 (en) * 2008-01-29 2015-06-23 Peter Forsell Method and instrument for treating obesity
US7844342B2 (en) 2008-02-07 2010-11-30 Ethicon Endo-Surgery, Inc. Powering implantable restriction systems using light
US8221439B2 (en) 2008-02-07 2012-07-17 Ethicon Endo-Surgery, Inc. Powering implantable restriction systems using kinetic motion
US8114345B2 (en) 2008-02-08 2012-02-14 Ethicon Endo-Surgery, Inc. System and method of sterilizing an implantable medical device
US8057492B2 (en) 2008-02-12 2011-11-15 Ethicon Endo-Surgery, Inc. Automatically adjusting band system with MEMS pump
US8591532B2 (en) 2008-02-12 2013-11-26 Ethicon Endo-Sugery, Inc. Automatically adjusting band system
US9044235B2 (en) 2008-02-18 2015-06-02 Covidien Lp Magnetic clip for implant deployment device
US9393002B2 (en) * 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US9398944B2 (en) 2008-02-18 2016-07-26 Covidien Lp Lock bar spring and clip for implant deployment device
US9034002B2 (en) * 2008-02-18 2015-05-19 Covidien Lp Lock bar spring and clip for implant deployment device
US9833240B2 (en) * 2008-02-18 2017-12-05 Covidien Lp Lock bar spring and clip for implant deployment device
US9393093B2 (en) * 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
US9301826B2 (en) * 2008-02-18 2016-04-05 Covidien Lp Lock bar spring and clip for implant deployment device
US8034065B2 (en) 2008-02-26 2011-10-11 Ethicon Endo-Surgery, Inc. Controlling pressure in adjustable restriction devices
US8233995B2 (en) 2008-03-06 2012-07-31 Ethicon Endo-Surgery, Inc. System and method of aligning an implantable antenna
US8187162B2 (en) 2008-03-06 2012-05-29 Ethicon Endo-Surgery, Inc. Reorientation port
US8262680B2 (en) 2008-03-10 2012-09-11 Ethicon Endo-Surgery, Inc. Anastomotic device
US11202707B2 (en) 2008-03-25 2021-12-21 Nuvasive Specialized Orthopedics, Inc. Adjustable implant system
AT10474U1 (de) 2008-04-15 2009-04-15 A M I Agency For Medical Innov Portkatheter zum einbringen einer flüssigkeit in ein hohlorgan eines menschlichen oder tierischen körpers
US9023063B2 (en) 2008-04-17 2015-05-05 Apollo Endosurgery, Inc. Implantable access port device having a safety cap
MX2010011367A (es) * 2008-04-17 2010-11-12 Allergan Inc Dispositivo con puerto de acceso implantable y sistema de sujecion.
US8070759B2 (en) 2008-05-30 2011-12-06 Ethicon Endo-Surgery, Inc. Surgical fastening device
US8114072B2 (en) 2008-05-30 2012-02-14 Ethicon Endo-Surgery, Inc. Electrical ablation device
US8317806B2 (en) 2008-05-30 2012-11-27 Ethicon Endo-Surgery, Inc. Endoscopic suturing tension controlling and indication devices
US8771260B2 (en) 2008-05-30 2014-07-08 Ethicon Endo-Surgery, Inc. Actuating and articulating surgical device
US8652150B2 (en) 2008-05-30 2014-02-18 Ethicon Endo-Surgery, Inc. Multifunction surgical device
US8679003B2 (en) 2008-05-30 2014-03-25 Ethicon Endo-Surgery, Inc. Surgical device and endoscope including same
US8906035B2 (en) 2008-06-04 2014-12-09 Ethicon Endo-Surgery, Inc. Endoscopic drop off bag
US8403926B2 (en) 2008-06-05 2013-03-26 Ethicon Endo-Surgery, Inc. Manually articulating devices
US8361112B2 (en) 2008-06-27 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical suture arrangement
US20100010294A1 (en) * 2008-07-10 2010-01-14 Ethicon Endo-Surgery, Inc. Temporarily positionable medical devices
US8888792B2 (en) 2008-07-14 2014-11-18 Ethicon Endo-Surgery, Inc. Tissue apposition clip application devices and methods
US8262563B2 (en) 2008-07-14 2012-09-11 Ethicon Endo-Surgery, Inc. Endoscopic translumenal articulatable steerable overtube
US8211125B2 (en) 2008-08-15 2012-07-03 Ethicon Endo-Surgery, Inc. Sterile appliance delivery device for endoscopic procedures
US8529563B2 (en) 2008-08-25 2013-09-10 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8241204B2 (en) 2008-08-29 2012-08-14 Ethicon Endo-Surgery, Inc. Articulating end cap
US8480689B2 (en) 2008-09-02 2013-07-09 Ethicon Endo-Surgery, Inc. Suturing device
US8409200B2 (en) 2008-09-03 2013-04-02 Ethicon Endo-Surgery, Inc. Surgical grasping device
US8114119B2 (en) 2008-09-09 2012-02-14 Ethicon Endo-Surgery, Inc. Surgical grasping device
US8337394B2 (en) 2008-10-01 2012-12-25 Ethicon Endo-Surgery, Inc. Overtube with expandable tip
WO2010042493A1 (en) 2008-10-06 2010-04-15 Allergan, Inc. Mechanical gastric band with cushions
US11241257B2 (en) 2008-10-13 2022-02-08 Nuvasive Specialized Orthopedics, Inc. Spinal distraction system
US20100185049A1 (en) 2008-10-22 2010-07-22 Allergan, Inc. Dome and screw valves for remotely adjustable gastric banding systems
CN102271737B (zh) 2008-10-31 2016-02-17 C·R·巴德股份有限公司 用于提供对患者皮下进入的进入端口
US8382756B2 (en) 2008-11-10 2013-02-26 Ellipse Technologies, Inc. External adjustment device for distraction device
US11890443B2 (en) 2008-11-13 2024-02-06 C. R. Bard, Inc. Implantable medical devices including septum-based indicators
US8932271B2 (en) 2008-11-13 2015-01-13 C. R. Bard, Inc. Implantable medical devices including septum-based indicators
US8157834B2 (en) 2008-11-25 2012-04-17 Ethicon Endo-Surgery, Inc. Rotational coupling device for surgical instrument with flexible actuators
US8172772B2 (en) 2008-12-11 2012-05-08 Ethicon Endo-Surgery, Inc. Specimen retrieval device
US8361066B2 (en) 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8828031B2 (en) 2009-01-12 2014-09-09 Ethicon Endo-Surgery, Inc. Apparatus for forming an anastomosis
US9226772B2 (en) 2009-01-30 2016-01-05 Ethicon Endo-Surgery, Inc. Surgical device
US8252057B2 (en) 2009-01-30 2012-08-28 Ethicon Endo-Surgery, Inc. Surgical access device
US8037591B2 (en) 2009-02-02 2011-10-18 Ethicon Endo-Surgery, Inc. Surgical scissors
US8197490B2 (en) 2009-02-23 2012-06-12 Ellipse Technologies, Inc. Non-invasive adjustable distraction system
US8328717B2 (en) * 2009-03-27 2012-12-11 Covidien Lp Seal device with adjustable aperture
JP5787875B2 (ja) * 2009-03-31 2015-09-30 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 機構を有する医療デバイス及び医療デバイス内における低摩擦合成材料の使用
US9622792B2 (en) 2009-04-29 2017-04-18 Nuvasive Specialized Orthopedics, Inc. Interspinous process device and method
US8715244B2 (en) 2009-07-07 2014-05-06 C. R. Bard, Inc. Extensible internal bolster for a medical device
US8506532B2 (en) * 2009-08-26 2013-08-13 Allergan, Inc. System including access port and applicator tool
US8715158B2 (en) 2009-08-26 2014-05-06 Apollo Endosurgery, Inc. Implantable bottom exit port
AU2015205820B2 (en) * 2009-08-26 2016-11-03 Apollo Endosurgery, Inc. System including access port and applicator tool
US8708979B2 (en) 2009-08-26 2014-04-29 Apollo Endosurgery, Inc. Implantable coupling device
US8449543B2 (en) 2009-09-04 2013-05-28 Ellipse Technologies, Inc. Bone growth device and method
US20110098704A1 (en) 2009-10-28 2011-04-28 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8608652B2 (en) 2009-11-05 2013-12-17 Ethicon Endo-Surgery, Inc. Vaginal entry surgical devices, kit, system, and method
CN105288836B (zh) 2009-11-17 2018-09-25 C·R·巴德股份有限公司 包括锚定装置和标识部分的包覆模制的进入端口
US8454494B2 (en) * 2009-12-14 2013-06-04 Ethicon Endo-Surgery, Inc. Support apparatus for gastric band system injector
US8968180B2 (en) 2009-12-14 2015-03-03 Ethicon Endo-Surgery, Inc. Apparatus for completing implantation of gastric band
US8202227B2 (en) 2009-12-14 2012-06-19 Ethicon Endo-Surgery, Inc. Pressure sensing adapter for gastric band system injector
US9060840B2 (en) 2009-12-16 2015-06-23 Ethicon Endo-Surgery, Inc. Needle targeting apparatus for implanted device
US20110144531A1 (en) * 2009-12-16 2011-06-16 Marcotte Amy L Gastric Band System Injector with Accelerometer
US8496574B2 (en) 2009-12-17 2013-07-30 Ethicon Endo-Surgery, Inc. Selectively positionable camera for surgical guide tube assembly
US8550981B2 (en) 2009-12-17 2013-10-08 Ethicon Endo-Surgery, Inc. Implantable port with vibratory feedback
US8353487B2 (en) 2009-12-17 2013-01-15 Ethicon Endo-Surgery, Inc. User interface support devices for endoscopic surgical instruments
US8506564B2 (en) 2009-12-18 2013-08-13 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US9028483B2 (en) 2009-12-18 2015-05-12 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US8591459B2 (en) 2009-12-21 2013-11-26 Ethicon Endo-Surgery, Inc. Use of biomarkers and therapeutic agents with surgical devices
US9443223B2 (en) * 2010-01-07 2016-09-13 Bimodal Llc System and method for hosting a social networking website having a theme of achievement
US8852118B2 (en) 2010-01-11 2014-10-07 Ethicon Endo-Surgery, Inc. Telemetry device with software user input features
US9005198B2 (en) 2010-01-29 2015-04-14 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US8882728B2 (en) 2010-02-10 2014-11-11 Apollo Endosurgery, Inc. Implantable injection port
US8758221B2 (en) 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8608642B2 (en) 2010-02-25 2013-12-17 Ethicon Endo-Surgery, Inc. Methods and devices for treating morbid obesity using hydrogel
US8840541B2 (en) 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
US10166380B2 (en) * 2010-04-12 2019-01-01 Po-Jen Ko Implantable venous device
US8738151B2 (en) 2010-04-28 2014-05-27 Medtronic, Inc. Body portal anchors and systems
US9028394B2 (en) 2010-04-29 2015-05-12 Apollo Endosurgery, Inc. Self-adjusting mechanical gastric band
US9044298B2 (en) 2010-04-29 2015-06-02 Apollo Endosurgery, Inc. Self-adjusting gastric band
US20110270024A1 (en) 2010-04-29 2011-11-03 Allergan, Inc. Self-adjusting gastric band having various compliant components
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
US8992415B2 (en) * 2010-04-30 2015-03-31 Apollo Endosurgery, Inc. Implantable device to protect tubing from puncture
US20110270021A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Electronically enhanced access port for a fluid filled implant
US8517915B2 (en) 2010-06-10 2013-08-27 Allergan, Inc. Remotely adjustable gastric banding system
US9248043B2 (en) 2010-06-30 2016-02-02 Ellipse Technologies, Inc. External adjustment device for distraction device
US8734488B2 (en) 2010-08-09 2014-05-27 Ellipse Technologies, Inc. Maintenance feature in magnetic implant
US20120041258A1 (en) 2010-08-16 2012-02-16 Allergan, Inc. Implantable access port system
US20120059216A1 (en) 2010-09-07 2012-03-08 Allergan, Inc. Remotely adjustable gastric banding system
US20120065460A1 (en) 2010-09-14 2012-03-15 Greg Nitka Implantable access port system
US10130503B2 (en) 2010-09-17 2018-11-20 Christopher John Couch Conical port
US8480560B2 (en) 2010-11-02 2013-07-09 Ethicon Endo-Surgery, Inc. Implantable medical port with fluid conduit retention sleeve
US9132264B2 (en) 2010-11-03 2015-09-15 Ethicon Endo-Surgery, Inc. Deployable and retractable member for injection port
US8905914B2 (en) 2010-11-03 2014-12-09 Ethicon Endo-Surgery, Inc. Gastric band device and method
US8632455B2 (en) 2010-11-12 2014-01-21 Ethicon Endo-Surgery, Inc. Gastric band with asymmetrical member
US8888677B2 (en) 2010-11-12 2014-11-18 Ethicon Endo-Surgery, Inc. Pressure limiting device for gastric band adjustment
US8961393B2 (en) 2010-11-15 2015-02-24 Apollo Endosurgery, Inc. Gastric band devices and drive systems
US8852217B2 (en) 2010-11-16 2014-10-07 Ethicon Endo-Surgery, Inc. Implantable injection port with tissue in-growth promoter
US9022923B2 (en) 2010-11-16 2015-05-05 Ethicon Endo-Surgery, Inc. Implantable injection port with tissue in-growth promoter
US9050446B2 (en) * 2010-11-16 2015-06-09 Ethicon Endo-Surgery, Inc. Port with conduit wraparound feature
USD676955S1 (en) 2010-12-30 2013-02-26 C. R. Bard, Inc. Implantable access port
USD682416S1 (en) 2010-12-30 2013-05-14 C. R. Bard, Inc. Implantable access port
US8960727B2 (en) * 2011-01-04 2015-02-24 Carefusion Corporation Method and system for visually indicating a secure connection
US10092291B2 (en) 2011-01-25 2018-10-09 Ethicon Endo-Surgery, Inc. Surgical instrument with selectively rigidizable features
WO2012112396A2 (en) 2011-02-14 2012-08-23 Ellipse Technologies, Inc. Device and method for treating fractured bones
US9254169B2 (en) 2011-02-28 2016-02-09 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9233241B2 (en) 2011-02-28 2016-01-12 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9314620B2 (en) 2011-02-28 2016-04-19 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9049987B2 (en) 2011-03-17 2015-06-09 Ethicon Endo-Surgery, Inc. Hand held surgical device for manipulating an internal magnet assembly within a patient
FR2974303B1 (fr) * 2011-04-22 2013-05-10 Cousin Biotech Organe de raidissement et dispositif implantable equipe d'un tel organe de raidissement.
US9974928B2 (en) 2011-05-10 2018-05-22 Safesharp Technologies Corporation Apparatus for securing a medical clamp to a patient
US8821373B2 (en) 2011-05-10 2014-09-02 Apollo Endosurgery, Inc. Directionless (orientation independent) needle injection port
US8663255B2 (en) 2011-08-09 2014-03-04 Ethicon Endo-Surgery, Inc. Gastric band with overmold
US8936582B2 (en) 2011-08-23 2015-01-20 Ethicon Endo-Surgery, Inc. Implantable medical port with alignment feature
US8801597B2 (en) 2011-08-25 2014-08-12 Apollo Endosurgery, Inc. Implantable access port with mesh attachment rivets
US10743794B2 (en) 2011-10-04 2020-08-18 Nuvasive Specialized Orthopedics, Inc. Devices and methods for non-invasive implant length sensing
US9199069B2 (en) 2011-10-20 2015-12-01 Apollo Endosurgery, Inc. Implantable injection port
US10016220B2 (en) 2011-11-01 2018-07-10 Nuvasive Specialized Orthopedics, Inc. Adjustable magnetic devices and methods of using same
US8858421B2 (en) 2011-11-15 2014-10-14 Apollo Endosurgery, Inc. Interior needle stick guard stems for tubes
US9089395B2 (en) 2011-11-16 2015-07-28 Appolo Endosurgery, Inc. Pre-loaded septum for use with an access port
US8876694B2 (en) 2011-12-07 2014-11-04 Apollo Endosurgery, Inc. Tube connector with a guiding tip
US8961394B2 (en) 2011-12-20 2015-02-24 Apollo Endosurgery, Inc. Self-sealing fluid joint for use with a gastric band
US8382775B1 (en) 2012-01-08 2013-02-26 Vibrynt, Inc. Methods, instruments and devices for extragastric reduction of stomach volume
US9314362B2 (en) 2012-01-08 2016-04-19 Vibrynt, Inc. Methods, instruments and devices for extragastric reduction of stomach volume
US8986199B2 (en) 2012-02-17 2015-03-24 Ethicon Endo-Surgery, Inc. Apparatus and methods for cleaning the lens of an endoscope
EP2822640B1 (en) * 2012-03-07 2020-02-05 DEKA Products Limited Partnership Infusion pump assembly
US9427255B2 (en) 2012-05-14 2016-08-30 Ethicon Endo-Surgery, Inc. Apparatus for introducing a steerable camera assembly into a patient
US20130338714A1 (en) 2012-06-15 2013-12-19 Arvin Chang Magnetic implants with improved anatomical compatibility
US9078662B2 (en) 2012-07-03 2015-07-14 Ethicon Endo-Surgery, Inc. Endoscopic cap electrode and method for using the same
US9545290B2 (en) 2012-07-30 2017-01-17 Ethicon Endo-Surgery, Inc. Needle probe guide
US9572623B2 (en) 2012-08-02 2017-02-21 Ethicon Endo-Surgery, Inc. Reusable electrode and disposable sheath
US10314649B2 (en) 2012-08-02 2019-06-11 Ethicon Endo-Surgery, Inc. Flexible expandable electrode and method of intraluminal delivery of pulsed power
US9277957B2 (en) 2012-08-15 2016-03-08 Ethicon Endo-Surgery, Inc. Electrosurgical devices and methods
US9044281B2 (en) 2012-10-18 2015-06-02 Ellipse Technologies, Inc. Intramedullary implants for replacing lost bone
IN2015DN03762A (zh) 2012-10-29 2015-10-02 Ellipse Technologies Inc
US10820984B2 (en) 2012-11-14 2020-11-03 ImplantADJUST, LLC Implant with elastomeric membrane and methods of fabrication thereof
US9351824B2 (en) 2012-11-14 2016-05-31 ImplantADJUST, LLC Adjustable implant with self-sealing elastomeric membrane and methods of fabrication thereof
US10098527B2 (en) 2013-02-27 2018-10-16 Ethidcon Endo-Surgery, Inc. System for performing a minimally invasive surgical procedure
US9179938B2 (en) 2013-03-08 2015-11-10 Ellipse Technologies, Inc. Distraction devices and method of assembling the same
US10252032B2 (en) 2013-03-12 2019-04-09 Medtronic, Inc. Socketed portal anchors and methods of using same
US9302043B2 (en) 2013-03-12 2016-04-05 Medtronic, Inc. Socketed portal anchors and methods of using same
US9352125B2 (en) 2013-03-12 2016-05-31 Medtronic, Inc. Portal anchors incorporating strain relief cup and systems using same
EP3013395B1 (en) * 2013-06-28 2019-10-02 Duc Hong Le Catheter anchoring device and method
US10226242B2 (en) 2013-07-31 2019-03-12 Nuvasive Specialized Orthopedics, Inc. Noninvasively adjustable suture anchors
US9801734B1 (en) 2013-08-09 2017-10-31 Nuvasive, Inc. Lordotic expandable interbody implant
CN105473178B (zh) 2013-08-20 2017-08-29 心脏起搏器股份公司 用于可植入装置的固定机构组件和方法
US10751094B2 (en) 2013-10-10 2020-08-25 Nuvasive Specialized Orthopedics, Inc. Adjustable spinal implant
US9707005B2 (en) 2014-02-14 2017-07-18 Ethicon Llc Lockout mechanisms for surgical devices
CN106456215B (zh) 2014-04-28 2020-04-10 诺威适骨科专科公司 用于调整医疗植入物的外部调整装置
WO2016065205A1 (en) 2014-10-23 2016-04-28 Ellipse Technologies, Inc. Remotely adjustable interactive bone reshaping implant
EP4005515B1 (en) 2014-12-26 2024-07-24 NuVasive Specialized Orthopedics, Inc. Systems for distraction
TWM503196U (zh) * 2015-01-14 2015-06-21 Reference Technology Ltd Company 立體定位穩定器
US10238427B2 (en) 2015-02-19 2019-03-26 Nuvasive Specialized Orthopedics, Inc. Systems and methods for vertebral adjustment
US10076387B2 (en) 2015-06-18 2018-09-18 Medtronic, Inc. Medical device implantation and positioning system
EP3361960B1 (en) 2015-10-16 2023-05-10 NuVasive Specialized Orthopedics, Inc. Adjustable devices for treating arthritis of the knee
EP3380017B1 (en) 2015-11-25 2024-10-23 CIRCA Scientific, Inc. Tissue engagement devices
EP4275631A3 (en) 2015-12-10 2024-02-28 NuVasive Specialized Orthopedics, Inc. External adjustment device for distraction device
ES2805657T3 (es) 2016-01-28 2021-02-15 Nuvasive Specialized Orthopedics Inc Sistemas para transporte óseo
WO2017139548A1 (en) 2016-02-10 2017-08-17 Nuvasive Specialized Orthopedics, Inc. Systems and methods for controlling multiple surgical variables
US10378661B2 (en) 2016-11-08 2019-08-13 Mueller International, Llc Valve body with integral bypass
RU173619U1 (ru) * 2017-05-04 2017-09-04 Общество с ограниченной ответственностью "Онколинн" Устройство для ввода имплантов в биологическую ткань
JP2019122769A (ja) * 2018-01-12 2019-07-25 エスエス イノベーションズ チャイナ カンパニー リミテッドＳＳ Ｉｎｎｏｖａｔｉｏｎｓ Ｃｈｉｎａ Ｃｏ． Ｌｔｄ ロボット手術システムのために滅菌アダプタアセンブリをアクチュエータアセンブリに固定させるロック装置
US11577097B2 (en) 2019-02-07 2023-02-14 Nuvasive Specialized Orthopedics, Inc. Ultrasonic communication in medical devices
US11589901B2 (en) 2019-02-08 2023-02-28 Nuvasive Specialized Orthopedics, Inc. External adjustment device
WO2021228826A1 (en) * 2020-05-11 2021-11-18 Biograil ApS Drug delivery device
US20220265324A1 (en) 2021-02-23 2022-08-25 Nuvasive Specialized Orthopedics, Inc. Adjustable implant, system and methods
US11737787B1 (en) 2021-05-27 2023-08-29 Nuvasive, Inc. Bone elongating devices and methods of use
WO2023014564A1 (en) 2021-08-03 2023-02-09 Nuvasive Specialized Orthopedics, Inc. Adjustable implant
WO2024100493A1 (en) * 2022-11-07 2024-05-16 Solventum Intellectual Properties Company Securement device for catheter, kit, and method of use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378023A (en) * 1980-05-29 1983-03-29 Trabucco Hector O Percutaneous insertable electrode device for the transitory or permanent stimulation of the heart or other organs and a method for implanting it
US5683447A (en) * 1995-12-19 1997-11-04 Ventritex, Inc. Lead with septal defibrillation and pacing electrodes
US5688247A (en) * 1992-06-30 1997-11-18 Hans Haindl Port catheter

Family Cites Families (203)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US36176A (en) * 1862-08-12 Improved mode of sifting and bagging grain
US560224A (en) * 1896-05-19 Machine for cutting soles
US5518A (en) * 1848-04-18 Geaijst-drieb
US2737954A (en) * 1954-02-12 1956-03-13 Gloria H Knapp Surgical stitching instrument with rotatable needle support
US3371352A (en) 1965-01-19 1968-03-05 Edwards Lab Inc Heart valve for quick implantation having provision for ingrowth of tissue
US3587115A (en) * 1966-05-04 1971-06-28 Donald P Shiley Prosthetic sutureless heart valves and implant tools therefor
US3686740A (en) * 1970-06-19 1972-08-29 Donald P Shiley Method of assemblying a sutureless heart valve
US3850324A (en) 1973-11-29 1974-11-26 K Meyer Threaded combination lock safety cap
ES8701408A1 (es) 1983-06-21 1986-11-16 Acec Dispositivo de enganche de un tapon de estrangulamiento para tubo guia
US4569675A (en) * 1983-09-12 1986-02-11 Infusaid Corporation Transcutaneous infusion system
CA1232814A (en) 1983-09-16 1988-02-16 Hidetoshi Sakamoto Guide wire for catheter
US4665906A (en) 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US4543088A (en) 1983-11-07 1985-09-24 American Hospital Supply Corporation Self-sealing subcutaneous injection site
US4621640A (en) 1984-01-09 1986-11-11 Mulhollan James S Mechanical needle carrier and method for its use
US4685447A (en) 1985-03-25 1987-08-11 Pmt Corporation Tissue expander system
US4592339A (en) * 1985-06-12 1986-06-03 Mentor Corporation Gastric banding device
US4840615A (en) * 1985-09-30 1989-06-20 Mcghan Medical Corporation Self-sealing injection reservoir
US4798584A (en) 1985-09-30 1989-01-17 Mcghan Medical Corporation Self-sealing injection reservoir
US4738657A (en) 1985-09-30 1988-04-19 Mcghan Medical Corporation Self-sealing injection reservoir
US4692146A (en) * 1985-10-24 1987-09-08 Cormed, Inc. Multiple vascular access port
US4710174A (en) 1985-12-16 1987-12-01 Surgical Engineering Associates, Inc. Implantable infusion port
US4778452A (en) * 1985-12-16 1988-10-18 Surgical Engineering Associates, Inc. Implantable infusion port
US4767410A (en) * 1985-12-16 1988-08-30 Surgical Engineering Associates, Inc. Implantable infusion port
US4673394A (en) 1986-01-17 1987-06-16 Strato Medical Corporation Implantable treatment reservoir
US4924865A (en) 1986-05-20 1990-05-15 Concept, Inc. Repair tack for bodily tissue
US4802885A (en) * 1986-06-17 1989-02-07 Medical Engineering Corporation Self sealing subcutaneous infusion and withdrawal device
US4781695A (en) * 1986-07-11 1988-11-01 Dalton Michael J Implantable fluid dispenser
US4704103A (en) 1986-08-21 1987-11-03 Burron Medical Inc. Implantable catheter means
US4762517A (en) * 1986-09-18 1988-08-09 Healthcare Technologies, Inc. Subcutaneously-implanted drug delivery system for intravenous injections, and the like
US4904241A (en) * 1986-10-16 1990-02-27 Medical Engineering Corp. Septum with a needle stop at the fluid transfer port
US4723948A (en) 1986-11-12 1988-02-09 Pharmacia Nu Tech Catheter attachment system
US4732948A (en) * 1986-12-02 1988-03-22 General Electric Company Solid phase polycondensation process for the production of high molecular weight polyetherimide ester polymers
US4772261A (en) 1987-01-29 1988-09-20 Board Of Regents, The University Of Texas System Intramedullary catheter
US4929239A (en) * 1987-02-16 1990-05-29 Aesculap-Werke Ag Vormals Jetter & Scheerer Device for filling the magazine of a scalp clip applicator with C-shaped scalp clips
US4781680A (en) * 1987-03-02 1988-11-01 Vir Engineering Resealable injection site
US4772270A (en) * 1987-06-18 1988-09-20 Catheter Technology Corp. Inseparable port/catheter tube assembly and methods
US5261914A (en) 1987-09-02 1993-11-16 Russell Warren Surgical fastener
US4892518A (en) * 1987-12-04 1990-01-09 Biocontrol Technology, Inc. Hemodialysis
US4834720A (en) * 1987-12-24 1989-05-30 Becton, Dickinson And Company Implantable port septum
US4880414A (en) 1987-12-31 1989-11-14 Pharmacia Nu Tech Catheter attachment system
US5108377A (en) * 1988-02-02 1992-04-28 C.R. Bard, Inc. Micro-injection port
US4978338A (en) * 1988-04-21 1990-12-18 Therex Corp. Implantable infusion apparatus
US4898585A (en) 1988-05-18 1990-02-06 Baxter Healthcare Corporation Implantable patient-activated fluid delivery device with bolus injection port
US4929236A (en) * 1988-05-26 1990-05-29 Shiley Infusaid, Inc. Snap-lock fitting catheter for an implantable device
AT391416B (de) * 1988-06-23 1990-10-10 Annemarie Schloegl Ges M B H M Septum fuer implantierbare vorrichtungen zur abgabe von wirkstoffen
US4861341A (en) 1988-07-18 1989-08-29 Woodburn Robert T Subcutaneous venous access device and needle system
US4929230A (en) 1988-09-30 1990-05-29 Pfleger Frederick W Syringe construction
NL8802577A (nl) * 1988-10-19 1990-05-16 Klaas Dijkstra Implanteerbare injectiekamerinrichting.
US5013298A (en) * 1989-02-13 1991-05-07 Surgical Engineering Associates, Inc. Laterally compressed septum assembly and implantable infusion port with laterally compressed septum
US5185003A (en) 1989-04-11 1993-02-09 B. Braun Melsungen Ag Port for injecting medicaments
US5045060A (en) * 1989-04-26 1991-09-03 Therex Corp. Implantable infusion device
US5041098A (en) * 1989-05-19 1991-08-20 Strato Medical Corporation Vascular access system for extracorporeal treatment of blood
US5129891A (en) * 1989-05-19 1992-07-14 Strato Medical Corporation Catheter attachment device
US5006115A (en) * 1989-07-25 1991-04-09 Medtronic, Inc. Needle placement sensor
US5133753A (en) 1989-08-07 1992-07-28 Medical Engineering Corporation Method for expanding a self-sealing tissue prosthesis
US5100392A (en) * 1989-12-08 1992-03-31 Biosynthesis, Inc. Implantable device for administration of drugs or other liquid solutions
US5137529A (en) * 1990-02-20 1992-08-11 Pudenz-Schulte Medical Research Corporation Injection port
US5350360A (en) 1990-03-01 1994-09-27 Michigan Transtech Corporation Implantable access devices
US5053013A (en) 1990-03-01 1991-10-01 The Regents Of The University Of Michigan Implantable infusion device
US5263930A (en) 1990-03-01 1993-11-23 William D. Ensminger Implantable access devices
US5281199A (en) 1990-03-01 1994-01-25 Michigan Transtech Corporation Implantable access devices
US5178612A (en) * 1990-10-10 1993-01-12 Strato Medical Corporation Compressible split cylinder bayonet locking device for attachment of a catheter to a fluid transfer device
US5127486A (en) * 1990-11-23 1992-07-07 Eaton-Kenway, Inc. System for sensing arrival of an automatic guided vehicle at a wire
US5123199A (en) * 1990-12-21 1992-06-23 Alexander Lysohir Fish hook guard
US5464407A (en) 1991-02-19 1995-11-07 Mcguire; David A. Flexible surgical screwdriver and methods of arthroscopic ligament reconstruction
US5207644A (en) * 1991-03-04 1993-05-04 Strecker Ernst P Device with implantable infusion chamber and a catheter extending therefrom
US5470010A (en) 1991-04-04 1995-11-28 Ethicon, Inc. Multiple fire endoscopic stapling mechanism
US5246156A (en) * 1991-09-12 1993-09-21 Ethicon, Inc. Multiple fire endoscopic stapling mechanism
US5174487A (en) 1991-04-04 1992-12-29 Ethicon, Inc. Endoscopic stapler and hernia repair mechanism
US5203864A (en) 1991-04-05 1993-04-20 Phillips Edward H Surgical fastener system
US5158547A (en) * 1991-04-08 1992-10-27 Medtronic, Inc. Drug administration device over full protection valve
US5090954A (en) * 1991-05-17 1992-02-25 Geary Gregory L Subcutaneous access device for peritoneal dialysis
RU1823791C (ru) 1991-06-17 1993-06-23 Юрий Андреевич Селезнев Фиксатор позвоночника и устройство дл его наложени
US5226429A (en) 1991-06-20 1993-07-13 Inamed Development Co. Laparoscopic gastric band and method
DE4211045A1 (de) 1992-04-02 1993-10-07 Zeljko Milosevic Implantierbarer Port
GR920100358A (el) * 1991-08-23 1993-06-07 Ethicon Inc Οργανο συρραφής χειρουργικής αναστομώσεως.
US5350104A (en) * 1991-08-23 1994-09-27 Ethicon, Inc. Sealing means for endoscopic surgical anastomosis stapling instrument
US5360407A (en) 1991-08-29 1994-11-01 C. R. Bard, Inc. Implantable dual access port with tactile ridge for position sensing
US5399168A (en) 1991-08-29 1995-03-21 C. R. Bard, Inc. Implantable plural fluid cavity port
US5318545A (en) * 1991-09-06 1994-06-07 Device Labs, Inc. Composite implantable biocompatible vascular access port device
US5213574A (en) * 1991-09-06 1993-05-25 Device Labs, Inc. Composite implantable biocompatible vascular access port device
US5305202A (en) 1991-11-12 1994-04-19 Quinton Instrument Company Ambulatory ECG analysis system
US5339168A (en) * 1991-12-31 1994-08-16 Xerox Corporation Copier/duplicator network
US5332398A (en) 1992-02-01 1994-07-26 Board Of Regents, The University Of Texas System Intramedullary catheter
US5217486A (en) 1992-02-18 1993-06-08 Mitek Surgical Products, Inc. Suture anchor and installation tool
DE4225524C2 (de) * 1992-08-01 1994-08-04 Fresenius Ag Implantierbare Infusionsvorrichtung
US5653718A (en) * 1994-05-16 1997-08-05 Yoon; Inbae Cannula anchoring system
US5540648A (en) * 1992-08-17 1996-07-30 Yoon; Inbae Medical instrument stabilizer with anchoring system and methods
US5364408A (en) * 1992-09-04 1994-11-15 Laurus Medical Corporation Endoscopic suture system
US5279564A (en) * 1992-09-11 1994-01-18 Edward Weck Incorporated Cannula retention device
US5601224A (en) 1992-10-09 1997-02-11 Ethicon, Inc. Surgical instrument
US5381943A (en) 1992-10-09 1995-01-17 Ethicon, Inc. Endoscopic surgical stapling instrument with pivotable and rotatable staple cartridge
US5328465A (en) * 1992-10-30 1994-07-12 Medtronic, Inc. Apparatus and method for limiting access to septum
JPH0798650B2 (ja) * 1993-01-11 1995-10-25 工業技術院長 板状水酸アパタイトの製造方法
US5449368A (en) * 1993-02-18 1995-09-12 Kuzmak; Lubomyr I. Laparoscopic adjustable gastric banding device and method for implantation and removal thereof
US5591143A (en) 1993-04-02 1997-01-07 Medrad Inc. Luer connector with torque indicator
US5601604A (en) 1993-05-27 1997-02-11 Inamed Development Co. Universal gastric band
US5527321A (en) 1993-07-14 1996-06-18 United States Surgical Corporation Instrument for closing trocar puncture wounds
US5423857A (en) 1993-11-02 1995-06-13 Ethicon, Inc. Three piece surgical staple
US5562618A (en) 1994-01-21 1996-10-08 Sims Deltec, Inc. Portal assembly and catheter connector
US5387192A (en) * 1994-01-24 1995-02-07 Sims Deltec, Inc. Hybrid portal and method
US5681330A (en) 1994-03-02 1997-10-28 Ethicon Endo-Surgery, Inc. Sterile occlusion fasteners and instrument and method for their placement
JPH07265326A (ja) * 1994-03-31 1995-10-17 Olympus Optical Co Ltd 医療用処置具
US5445616A (en) * 1994-04-29 1995-08-29 Medtronic, Inc. Medication delivery device and method of construction
US5476460A (en) 1994-04-29 1995-12-19 Minimed Inc. Implantable infusion port with reduced internal volume
US5607407A (en) 1994-05-09 1997-03-04 Tolkoff; Marc J. Catheter assembly
US5573540A (en) 1994-07-18 1996-11-12 Yoon; Inbae Apparatus and method for suturing an opening in anatomical tissue
US5582616A (en) 1994-08-05 1996-12-10 Origin Medsystems, Inc. Surgical helical fastener with applicator
US5545152A (en) 1994-10-28 1996-08-13 Minimed Inc. Quick-connect coupling for a medication infusion system
US5725493A (en) 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US5603723A (en) * 1995-01-11 1997-02-18 United States Surgical Corporation Surgical instrument configured to be disassembled for cleaning
US5976159A (en) 1995-02-24 1999-11-02 Heartport, Inc. Surgical clips and methods for tissue approximation
US5954687A (en) * 1995-04-28 1999-09-21 Medtronic, Inc. Burr hole ring with catheter for use as an injection port
US5637102A (en) 1995-05-24 1997-06-10 C. R. Bard, Inc. Dual-type catheter connection system
US5989216A (en) 1995-06-29 1999-11-23 Sims Deltec, Inc. Access portal and method
US6102922A (en) 1995-09-22 2000-08-15 Kirk Promotions Limited Surgical method and device for reducing the food intake of patient
US5773019A (en) * 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5635718A (en) * 1996-01-16 1997-06-03 Minnesota Mining And Manufacturing Company Multi-module radiation detecting device and fabrication method
US5716370A (en) * 1996-02-23 1998-02-10 Williamson, Iv; Warren Means for replacing a heart valve in a minimally invasive manner
US5817062A (en) 1996-03-12 1998-10-06 Heartport, Inc. Trocar
US5602224A (en) 1996-03-19 1997-02-11 Siltech Inc. Silicone alkyl quats
US5718682A (en) 1996-06-28 1998-02-17 United States Surgical Corporation Access port device and method of manufacture
US5830221A (en) 1996-09-20 1998-11-03 United States Surgical Corporation Coil fastener applier
US5792104A (en) 1996-12-10 1998-08-11 Medtronic, Inc. Dual-reservoir vascular access port
US6086555A (en) 1997-01-17 2000-07-11 C. R. Bard, Inc. Dual reservoir vascular access port with two-piece housing and compound septum
ATE429181T1 (de) * 1997-02-06 2009-05-15 Howmedica Osteonics Corp Erweiterbare, gewindelose vorrichtung zur wirbelsäulenfusion
DE19706139C1 (de) 1997-02-18 1998-10-01 Tricumed Gmbh Implantierbares Doppel-Zuspritzport
US5871532A (en) 1997-05-22 1999-02-16 Sulzer Intermedics Inc. Epicardial lead for minimally invasive implantation
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US5975159A (en) * 1997-09-09 1999-11-02 Fogg Filler Company Container filler apparatus external disconnect valve
US6183444B1 (en) * 1998-05-16 2001-02-06 Microheart, Inc. Drug delivery module
US6190352B1 (en) 1997-10-01 2001-02-20 Boston Scientific Corporation Guidewire compatible port and method for inserting same
DE19745654A1 (de) 1997-10-16 1999-04-22 Hans Peter Prof Dr Med Zenner Vorrichtung zur subkutanen Infusion und deren Verwendung
DE19751791A1 (de) 1997-11-22 1999-05-27 Arnold Dipl Ing Dr Med Pier Chirurgisches Klammersetzinstrument
US6213973B1 (en) 1998-01-12 2001-04-10 C. R. Bard, Inc. Vascular access port with elongated septum
US6146387A (en) * 1998-08-26 2000-11-14 Linvatec Corporation Cannulated tissue anchor system
FR2782632B1 (fr) * 1998-08-28 2000-12-29 Materiel Orthopedique En Abreg Cage de fusion intersomatique expansible
JP3046008B2 (ja) 1998-09-25 2000-05-29 株式会社クリニカル・サプライ 薬液注入装置
WO2000033901A1 (en) 1998-12-07 2000-06-15 Std Manufacturing, Inc. Implantable vascular access device
DE19860444C2 (de) * 1998-12-28 2001-03-29 Storz Karl Gmbh & Co Kg Handgriff für ein medizinisches Rohrschaftinstrument
FR2794360B1 (fr) 1999-06-03 2001-08-24 Bourhane Eddine Benelouezzane Prothese de derivation biliaire
US6461292B1 (en) * 1999-08-12 2002-10-08 Obtech Medical Ag Anal incontinence treatment with wireless energy supply
US6319226B1 (en) 1999-09-20 2001-11-20 Scimed Life Systems, Inc. Implantable vascular access device
US6470892B1 (en) * 2000-02-10 2002-10-29 Obtech Medical Ag Mechanical heartburn and reflux treatment
MXPA02007649A (es) 2000-02-10 2004-08-23 Potencia Medical Ag Tratamiento para la incontinencia urinaria con suministro de energia inalambrica.
DE60111019T2 (de) * 2000-02-14 2006-05-11 Potencia Medical Ag Penisprothese
CA2407643C (en) 2000-04-26 2009-06-30 Std Manufacturing, Inc. Implantable hemodialysis access device
US6592571B1 (en) 2000-05-24 2003-07-15 Medtronic, Inc. Drug pump with suture loops flush to outer surface
US6478783B1 (en) 2000-05-26 2002-11-12 H. Robert Moorehead Anti-sludge medication ports and related methods
US6447524B1 (en) 2000-10-19 2002-09-10 Ethicon Endo-Surgery, Inc. Fastener for hernia mesh fixation
US6556857B1 (en) 2000-10-24 2003-04-29 Sdgi Holdings, Inc. Rotation locking driver for image guided instruments
US7152601B2 (en) 2000-12-18 2006-12-26 Mohamed Ali Barakat Strapless respiratory face mask
EP1222903B1 (de) * 2001-01-12 2005-01-19 Link Spine Group, Inc. Chirurgisches Instrument zum Einsetzen einer Zwischenwirbelendoprothese
KR100354828B1 (ko) 2001-03-12 2002-10-05 주식회사 씨엠리서치 생분해성 폴리에스테르의 제조방법 및 그에 의해 제조된생분해성 폴리에스테르
EP1383854B1 (en) 2001-04-20 2007-03-14 Dow Global Technologies Inc. Separation of plant oil triglyceride mixtures by solid bed adsorption
US6535764B2 (en) * 2001-05-01 2003-03-18 Intrapace, Inc. Gastric treatment and diagnosis device and method
US6511490B2 (en) 2001-06-22 2003-01-28 Antoine Jean Henri Robert Gastric banding device and method
US6607504B2 (en) * 2001-06-29 2003-08-19 Scimed Life Systems, Inc. Percutaneous access
ES2393101T3 (es) 2001-08-29 2012-12-18 Ricardo A. P. De Carvalho Sistema implantable y sellable para la administración unidireccional de agentes terapéuticos a tejidos diana
US6648917B2 (en) * 2001-10-17 2003-11-18 Medicinelodge, Inc. Adjustable bone fusion implant and method
JP3934916B2 (ja) 2001-11-06 2007-06-20 オペロンテックス株式会社 伸縮性不織布およびその製造方法
US6827722B1 (en) 2001-12-11 2004-12-07 Biomet, Inc. Method and apparatus for use of a guide wire capturing surgical instrument
KR100474747B1 (ko) * 2001-12-13 2005-03-08 주식회사 솔고 바이오메디칼 추체간 삽입되는 인공보철물 및 인공보철물 삽입기구
JP4014419B2 (ja) * 2002-02-15 2007-11-28 オリンパス株式会社 外科用処置具
US6988987B2 (en) * 2002-03-18 2006-01-24 Olympus Corporation Guide tube
US20030181890A1 (en) * 2002-03-22 2003-09-25 Schulze Dale R. Medical device that removably attaches to a bodily organ
US7076309B2 (en) * 2002-04-30 2006-07-11 Medtronic, Inc. Apparatus and method for fixedly engaging an electrical lead
GB2389791B (en) * 2002-04-30 2006-12-13 Steven Gill Implantable drug delivery pump
US6976159B1 (en) 2002-08-29 2005-12-13 Crystal Group Inc. SMTP method and system for simultaneously configuring a plurality of remote management appliances
US6695861B1 (en) † 2002-09-20 2004-02-24 Interrad Medical, Inc. Sutureless retention device
US20040068233A1 (en) * 2002-10-04 2004-04-08 Dimatteo Kristian Venous access device with detachable suture wings
CN1202879C (zh) * 2002-10-14 2005-05-25 上海亚医科技开发有限公司 内置放射微粒带刻度可弯曲金属穿刺植入器
US20040093056A1 (en) 2002-10-26 2004-05-13 Johnson Lianw M. Medical appliance delivery apparatus and method of use
ATE454864T1 (de) 2003-03-28 2010-01-15 Gi Dynamics Inc Schlauch zur verzögerten einleitung von enzymen in den darm
WO2004087014A2 (en) 2003-03-28 2004-10-14 Gi Dynamics, Inc. Anti-obesity devices
US20040199129A1 (en) * 2003-04-07 2004-10-07 Scimed Life Systems, Inc. Vascular access port
US20050131352A1 (en) 2003-06-16 2005-06-16 Conlon Sean P. Subcutaneous injection port for applied fasteners
US7374557B2 (en) * 2003-06-16 2008-05-20 Ethicon Endo-Surgery, Inc. Subcutaneous self attaching injection port with integral fasteners
US7850660B2 (en) * 2003-12-19 2010-12-14 Ethicon Endo-Surgery, Inc. Implantable medical device with simultaneous attachment mechanism and method
US7561916B2 (en) * 2005-06-24 2009-07-14 Ethicon Endo-Surgery, Inc. Implantable medical device with indicator
US7862546B2 (en) 2003-06-16 2011-01-04 Ethicon Endo-Surgery, Inc. Subcutaneous self attaching injection port with integral moveable retention members
US8715243B2 (en) 2003-06-16 2014-05-06 Ethicon Endo-Surgery, Inc. Injection port applier with downward force actuation
EP2311520B1 (en) 2003-09-15 2014-12-03 Apollo Endosurgery, Inc. Implantable device fastening system
DE10348451B4 (de) 2003-10-17 2008-11-06 Keiper Gmbh & Co.Kg Verriegelungsvorrichtung für einen Fahrzeugsitz und Fahrzeugsitz mit einer schwenkbaren Lehne und einer derartigen Verriegelungsvorrichtung
US8162897B2 (en) * 2003-12-19 2012-04-24 Ethicon Endo-Surgery, Inc. Audible and tactile feedback
ATE489897T1 (de) 2004-01-23 2010-12-15 Allergan Inc Befestigungssystem für eine implantierbare vorrichtung und anwendungsverfahren
US20050277899A1 (en) 2004-06-01 2005-12-15 Conlon Sean P Method of implanting a fluid injection port
US20050148956A1 (en) * 2004-06-01 2005-07-07 Conlon Sean P. Surgically implantable injection port having an improved fastener
US7608080B2 (en) * 2004-07-02 2009-10-27 Warsaw Orthopedic, Inc. Device for inserting implants
US7468164B2 (en) * 2004-07-28 2008-12-23 Expert Services Group, Inc. Automated fluid handling cartridge and fluid processing system
US7585280B2 (en) 2004-12-29 2009-09-08 Codman & Shurtleff, Inc. System and method for measuring the pressure of a fluid system within a patient
US7909804B2 (en) 2005-02-07 2011-03-22 C. R. Bard, Inc. Vascular access port with integral attachment mechanism
US8016744B2 (en) 2005-02-24 2011-09-13 Ethicon Endo-Surgery, Inc. External pressure-based gastric band adjustment system and method
US20080009680A1 (en) 2005-06-24 2008-01-10 Hassler William L Jr Remote monitoring and adjustment of a food intake restriction device
US20060217673A1 (en) * 2005-03-22 2006-09-28 Schulze Dale R Subcutaneous injection port with stabilizing elements
US20060217668A1 (en) 2005-03-22 2006-09-28 Schulze Dale R Method of implanting a subcutaneous injection port having stabilizing elements
US7241632B2 (en) 2005-04-14 2007-07-10 Headway Technologies, Inc. MTJ read head with sidewall spacers
US7651483B2 (en) * 2005-06-24 2010-01-26 Ethicon Endo-Surgery, Inc. Injection port
US7918844B2 (en) 2005-06-24 2011-04-05 Ethicon Endo-Surgery, Inc. Applier for implantable medical device
US7762999B2 (en) 2006-02-01 2010-07-27 Ethicon Endo-Surgery, Inc. Injection port
US8328836B2 (en) * 2006-05-01 2012-12-11 Ethicon Endo-Surgery, Inc. Flexible endoscopic safety needle
US20070208313A1 (en) * 2007-05-07 2007-09-06 Ethicon Endo-Surgery, Inc. Method of implanting a fluid injection port
US8550981B2 (en) * 2009-12-17 2013-10-08 Ethicon Endo-Surgery, Inc. Implantable port with vibratory feedback

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378023A (en) * 1980-05-29 1983-03-29 Trabucco Hector O Percutaneous insertable electrode device for the transitory or permanent stimulation of the heart or other organs and a method for implanting it
US5688247A (en) * 1992-06-30 1997-11-18 Hans Haindl Port catheter
US5683447A (en) * 1995-12-19 1997-11-04 Ventritex, Inc. Lead with septal defibrillation and pacing electrodes

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