CN1879788A - Virus-clearing capsule - Google Patents

Abstract

The invention provides a capsule which is prepared from Echinacea purpurea extract, honeysuckle flower extract, toasted garlic extract, root of kudzu vine extract,purple perilla extract, licorice extract, vitamin C and selenium through the steps of mixing, stirring, loading into capsules, sealing, inspecting and packaging. The capsule can be used for treating influenza and common cold.

Description

Virus-clearing capsule

One, technical field: the invention belongs to the functional health-care food field, relate in particular to the health food that processes with raw materials such as Echinacea extract, Flos Lonicerae extract, Bulbus Allii extract, Radix Puerariae extract, Folium perillae extract, Radix Glycyrrhizae extract, herba houttuyniae extract, vitamin C, selenium.

Two, background technology: the health food that the present invention processes with Echinacea, Flos Lonicerae, Bulbus Allii, Radix Puerariae, Folium Perillae, Radix Glycyrrhizae extract, vitamin C, selenium etc.That this product has is antibiotic, antiviral, antiinflammatory, resisiting influenza virus, control cold virus, improve immunologic function etc.Existing market is not that antibiotic, the antiviral of raw material, the product of preventing and treating influenza, flu, raising immunologic function occur with natural medicine-food dual purpose plant extract not also, develops this product and can be market a kind of novel health food is provided.Compare with the popular product of existing market, this product has the natural plants new product of unique function.

Three, summary of the invention: The present invention be directed to the popular of SARS in 2003, people have recognized the disease by viral infection, SARS, the plague, Aids fearful, 2004,2005,2006 global bird flu (H5NI virus) be very popular, and at ordinary times whenever seasonal variations, changes in temperature replace, and the just big row of influenza is wreaked havoc.Existing over one hundred time of human up to now influenza pandemic, global being very popular just has five times more than, billions of for this reason people's morbidities, tens of millions of people's death.Influenza has become the epidemic disease that human society must solve, and appropriate authority is strengthened the prevention work of influenza one after another both at home and abroad.World Health Organization (WHO) has sent influenza possibility pandemic " alarm " now, will cause grave danger for human health, is that people more and more pay close attention to the issuable damaging influence of global infectious disease.Promptly to research and development and the production defence common cold and the grippal food of this series products, health food has special social meaning, is people's livelihood exigence, and a kind of functional health-care food of development.That this product has is antibiotic, antiviral, antiinflammatory, prevent and treat multiple effects such as influenza, flu, raising immunologic function.Product is a hard capsule, does not have any abnormal flavour, carries taking convenience.

Four, composition of raw materials: Echinacea extract 10-40 kilogram, Flos Lonicerae extract 20-60 kilogram, Bulbus Allii extract 20-50 kilogram, Radix Puerariae extract 30-50 kilogram, Folium perillae extract 20-50 kilogram, Radix Glycyrrhizae extract 20-60 kilogram, herba houttuyniae extract 20-50 kilogram, vitamin C 10-50 kilogram, selenium 2.5-10 milligram.

Five, technical scheme:

(1) Echinacea extract (Echinacea extract) has another name called SONGGUOJU, is the wild flowers of a kind of Compositae, originate in North America, mainly be distributed in the U.S. central and east and Canada south, introduce China the nineties, now at ground establishing in large scale such as China Shanghai, Beijing, Anhui.

Comprehensive pharmaceutical research achievement for many years, the main pharmacologically active of Echinacea can be summed up as following aspect: 1, activate the promotion leukocyte; 2, suppress hyaluronidase; 3, strengthen cytophagy; 4, stimulate interferon to generate; 5, excite and be equipped with bright element/complement system; 6, antiinflammatory action; 7, antibacterial action; 8, antiviral activity, 9, stimulate adrenal cortex; 10, sanatory new organization generates.These pharmacodynamics effects are interrelated, and the performance comprehensive function promotes immune function of human body jointly, the pathogenic microorganism that resists an invasion, and it is plain to help body to remove virus, repairs body injury, and people are got well.

The clinical research data show, Echinacea has outstanding curative effect to many infectivities and inflammation disease, is described as " natural antibiotics "; It has very important therapeutic value to many diseases relevant with human immune system's function, and the title of " natural immunity regulator " is arranged.Echinacea was accepted use by the doctor of Europe, the regular hospital of the U.S. as the natural plants medicine, and The World Health Organization (WHO) has also announced the treatment specialist paper of Echinacea in 1999.The jinx who is called as 21 century pharyngolaryngitis, flu.

Sum up according to modern clinical trial, Echinacea is mainly effective to following disease: influenza and flu, particularly early stage in outbreak; Tonsil, oral cavity and throat infection, have a toothache, gingival infection, cough, bronchitis, outward injure wound infection, burn, urethra and genital system infection, monilial infection, comprise multiple efficacies such as aphtha, pharyngitis, glossitis, vaginitis and vulvitis.

Chemical constituent: Echinacea mainly contains sugar, caffeic acid derivant, polyacetylene and isopropylformic acid. amine.Volatile oil, flavone, alkaloid, phytosterol raw sugar, multiple compositions such as unsaturated ketone, vitamin A, vitamin C, vitamin E, mineral potassium, calcium, iodine, sulfur, magnesium, ferrum, zinc.

Pharmacological action: 1, antibiotic Echinacea confirms in vitro tests, and staphylococcus aureus and streptococcus pyogenes are had the activity of inhibition; The polyacetylene constituents has strong inhibitory activity to bacillus pyocyaneus and escherich's bacillus; Echinacea extract discharges has inhibitory action to mycobacterium tuberculosis, can suppress the growth of the bright bacterium of epidermis.

Echinacea extract all has the inhibitory action of distinct program to clinical isolating staphylococcus aureus, B family streptococcus, klebsiella spp, hemophilus influenza and epidermis coccus.Inhibitory action to staphylococcus aureus, B family streptococcus, staphylococcus epidermidis is stronger.

Animal experiment shows that Echinacea can reduce the animal dead rate that is caused by infection of staphylococcus aureus, shows that it has certain protective role to the infection of staphylococcus aureus animal.Echinacea extract can make streptococcal infection termination in the rat body.Echinacea can suppress the intravital infection diffusion of laboratory animal effectively; this effect is relevant with the mechanism of action that it suppresses hyaluronidase; the invasion of hyaluronic acid protection cells from microorganisms is difficult for by infected by microbes and breeding tissue, and hyaluronidase then plays the bright hyaluronic effect of branch.

2, antifungal activity: the Echinacea polysaccharide has antifungic action.The mouse model of immunodeficiency can make the interior candida albicans infection of mice kidney significantly reduce, and make the lethal dose monilial infection that significant protective effect be arranged with the treatment of Echinacea polysaccharide.Test shows that Echinacea can strengthen the ability that the mouse immune cell suppresses Candida albicans.Healthy people's mononuclear cell increases the oidiomycetic phagocytic activity of white after handling with Echinacea extract.

3, antiviral: Echinacea is described as " outstanding antivirus plant medicine " by external expert.The Echinacea antivirus action mainly is to rely on to stimulate the T-cytoactive to promote interferon to produce.In addition, Echinacea extract suppresses the Causative virus that some causes respiratory tract infection in cell culture, comprise influenza virus and herpesvirus.

Echinacea extract has the obvious suppression effect to influenza virus, herpesvirus and poliomyelitis virus; Echinacea extract has the inhibition active function to influenza virus A2, and (EMC-Virus) and filterability Stomatovirus (VSV) duplicate can also to suppress encephalomyocarditis virus.The Echinacea polysaccharide is antiviral main component, herpes simplex virus is duplicated 80% inhibitory action.

College of Pharmacy, Beijing Univ's research worker has been carried out the antiviral test in Echinacea inside and outside, the result shows, Echinacea has obvious inhibitory action to influenza virus, and virus COXB3, COXB5 of A Saqi family and breathing are closed herpes virus RSV, and herpesvirus HSV-2 has certain inhibitory action.To the mice pneumonia due to the influenza virus, continuous 5 days gastric infusions of Echinacea can obviously reduce pneumonia, and the lung index alleviates than matched group is obvious, show that Echinacea has obvious inhibitory action to influenza virus induced mice pneumonia.

4, infection: as if in the pharmacological experiment study, Echinacea and ingredient thereof have only gentle antibacterial activity in vivo and in vitro.Yet amazing is that the various goods that contain Echinacea have all shown powerful wide spectrum infection effect in clinical.Obviously, the anti-infectious function of Echinacea is not simple kill and suppress the pathogen effect, but deeper mechanism is arranged.

To be health invaded and harassed by microorganisms such as antibacterial, virus, funguses in infection, and not every microorganism can both cause infection, neither all exposures or the people of contact pathogenic microorganism all ill.

Foreign medical science the expert discover, the powerful anti-infectious function of Echinacea is except that direct inhibition pathogen, and main is by activating the immune system of body, improving immunity of human body itself and bring into play effectiveness.The main mechanism of action of the effective anti-infective of Echinacea is: (1), excite macrophage activity.(2), increase the cytophagy activity.(3), stimulate the increment of T one cell.(4), promote the interferon cytokine to generate.

Echinacea is this to promote immunologic function, and transfer the human body self resistance anti-infective mechanism and antibiosis are have essential difference, be a kind of positive therapeutic mode, treating both the principal and secondary aspects of a disease.

5, antiinflammatory action: inflammatory reaction is the normal defense reaction of body tissue to various infection and non-infectious injury, is the main pathological change of many diseases.

Pharmacological evaluation and clinical studies show, Echinacea have extremely strong anti-inflammatory activity, and its anti-inflammatory activity comes from the inhibition hyaluronidase, stimulate adrenal cortex, suppress pro-inflammatory cytokine cyclooxygenase, the cured oxygenase of 5-and arachidonic active function.

6, raise immunity: it is reported that as far back as 19th century, people just find that Echinacea can improve the resistance of human body to various infectious disease.A series of pharmacology and clinical research show that Echinacea is anti-infection ability widely, are because Echinacea can significantly improve body immunity.Therefore it is fruitful to be used for the treatment of various infectious disease.Now, Echinacea is the foremost immunomodulating medical herbs of western countries.Because Echinacea treatment flu, influenza and the various infectious disease of whole body are the most effective, and the human immune system is had facilitation.The medical expert goes through meticulous further investigation in tens of years, Echinacea has regulates human immune system's effect, mainly is that macrophage and other effector lymphocyte by system plays a role, and improves human body monitoring system, particularly mucomembranous immune system Vigilance and vigor are defeated the pathogen of invasion.

7, antitumor: Echinacea is by several mechanism performance antitumor actions, and main the dependence promotes immunity, stimulates macrophage to produce tumor necrosis factor, and cytokines such as interleukin and interferon are killed or suppressed tumor cell.

Studies confirm that Echinacea excites medullary cell to produce cytokine, promote bone-marrow-derived lymphocyte propagation, suppress tumor cell.The Echinacea polysaccharide just has anti-tumor activity under extremely low concentration, it has strong row activation to macrophage, and after these cells were activated, the secretion that increases oxygen base and interleukin-1 produced, tumor cell there is cytotoxicity, directly kills P815 oncocyte activity.After the oral Echinacea of mice of inoculation Meth A tumor cell was squeezed the juice, demonstration can suppress tumor growth.The laboratory in vitro study finds that the derived essential oil of Echinacea has the activity of inhibition to P-388 leukemic lymphoblastoid cell.

8, antioxidation: increasing experiment confirm, the relevant antioxidant with human body of many common diseases is relevant, for example: respiratory tract infection, periodontal disease, rheumatoid arthritis, cardiovascular diseases, cancer, dermatosis etc.Use antioxidant can make the oxygen-derived free radicals inactivation, the treatment relevant disease.

Polyphenols compositions such as the Echinacea glycosides in the Echinacea, chicoric acid, caffeic acid have the effect of the free radical of elimination, can protect skin collagen III to avoid the infringement of free radical cracking, can be used for prevention and treatment illumination skin injury.

Clinical effect: 1, treatment flu has specially good effect: the Echinacea treatment is most widely used, curative effect is best, and study maximum is that treatment is gone up the breathing liquid inductance and dyed, and comprises flu, influenza, tonsillitis, bronchitis and cough; Treatment flu and influenza curative effect are particularly remarkable.

Echinacea relies on the effectiveness of the anti-flu of multiple mechanism of action performance, influenza.Echinacea performance activating immune system; inducement interferon; stop virus replication; the protection cell membrane; blocking virus is to the invasion and attack of mucosa endotheliocyte, and multiple biological effects such as antiinflammatory and antiallergic action, and common the resistance caught a cold and the influenza virus invasion; the curative effect highly significant, early stage result of use is good especially.The model of action of the anti-flu of Echinacea is different with Chinese medicine, and the effect that it can be brought into play antiviral simultaneously and improve immunity has the double effects of separating the harmony in the exterior tonic concurrently, we can say treating both the principal and secondary aspects of a disease.Therefore Echinacea can both use in any stage of flu, particularly in the common cold initial stage better effects if, when first symptom that you feel to catch a cold, take the Echinacea preparation immediately flu is ended fast, perhaps mitigation symptoms, shorten the course of disease, strengthened patient's resistance against diseases simultaneously.

Recently, the relevant clinical test results of expert's analysis-by-synthesis proposes, the Echinacea preparation can be treated and preventing cold effectively, at flu and influenza outbreak initial stage, with the Echinacea treatment, can effectively alleviate flu and flu-like symptom in a short time, fast track rehabilitation, and the minimizing cold symptoms, for example cough, pharyngalgia, headache, limb pain, heating are unable etc.

In addition, Echinacea is mitigation symptoms effectively, shortens the course of disease, treating both the principal and secondary aspects of a disease double effects, the effect of preventing cold and influenza.

2, treatment pharyngolaryngitis: pharyngolaryngitis is that Echinacea is effectively treated the field.Many randomized, double-blind placebo-controlled trials confirm that Echinacea has mitigation to multiple pharyngolaryngitis, to the viral infection better effects if.Can suppress the various symptoms of infection with the Echinacea treatment, and can fast track rehabilitation.To some severe infections, select for use Echinacea as antibiotic auxiliary therapeutical agent, the effect that shortens the course of disease and mitigation symptoms is arranged, the clinical research result who carries out affirms fully Echinacea treatment pharyngolaryngitis infection disease up to now better curative effect.

3, the treatment child goes up sense, safe and effective: Echinacea treatment childhood upper respiratory tract infection, comprise the clinical trial of flu, all demonstrate good safety and effectiveness, in 209 3-5 of Echinacea treatment year flu child's the clinical trial, Echinacea and matched group are relatively, can obviously reduce the natural law of the ill heating of child, other contrast clinical trial proves that also Echinacea is effective to children's cold and influenza.

The Germany physician is to 1280 comparative study results that suffer from bronchitic child with the Echinacea treatment, discovery is compared with other therapies with the Echinacea treatment, can significantly shorten the course of disease and quicken the disease recovery from illness, even it is better with antibiotic than single, because mostly being viral infection, bronchitis causes, use the antibiotic curative effect relatively poor separately, and Echinacea can be brought into play promotion immunologic function and antiviral dual function.Studies show that the patient of " lung dry cough " or obstructive tracheitis improves the most remarkable, antibiotic and Echinacea share the treatment better efficacy.

(3) Bulbus Allii extract: Bulbus Allii is the bulb of Bulbus Lilii tannin plant Bulbus Allii, warm in nature, acrid in the mouth.Have detumescence squama poison, functions such as parasite killing, modern study think have antipathogen, sterilization, antiinflammatory, antiviral.Enhancing immunity, effect such as anticancer.

Chemical constituent: Bulbus Allii mainly contains volatile oil, contains the sulfide compound that multiple pi-allyl, ethyl and methyl are formed in the volatile oil, compositions such as big allistatin, big plain new element, saccharide, several amino acids, protein and thick thousand dimension.

Pharmacological action:

1, raise immunity: Bulbus Allii can obviously be improved the mouse macrophage phagocytic activity, quickens the Congo red granule and removes from blood.Anthroposcopy shows that behind the injection garlic juice, lymphoblastic transformation rate and the reaction of rose soul bow structure are all significantly increased.According to another report, oral Bulbus Allii homogenate can obviously strengthen immunity and the specific cellular immunity and the non-specific immunity of mouse cell.

2, antibiotic: Bulbus Allii volatile oil has intensive bactericidal action.Its 0.5% aqueous solution can be killed Bacillus typhi in 5 minutes.Bulbus Allii juice leachate and allicin are to staphylococcus, meningococcus.Streptococcus pneumoniae, diphtheria corynebacterium, dysentery bacterium, escherichia coli, Bacillus typhi, Salmonella paratyphi, tubercule bacillus etc. all have obvious suppression and killing action.The purple garlic effect is strong than the Rhizoma Euonymus Bulbus Allii, and garlic preparation is to penicillin, streptomycin, chloromycetin, and drug-fast bacterium pearl is still responsive, and the inhibitory potency of natural garlicin is similar to the synthetic product.

3, antitumor: contain multiple cancer-resisting substance in the Oleum Bulbus Allii, Oleum Bulbus Allii can be blocked antibacterial, the mycete reduction to the nitrous amine salt, blocking-up antibacterial, mycete are to the synthetic facilitation of nitrous amine salt, because the nitrosamine salt compound can bring out the multiple formation of organizing the organ pipe tumor, Oleum Bulbus Allii can obviously reduce the intravital nitrosamine salt content of people, show through studying for a long period of time, eat Bulbus Allii more and can reduce by 60% incidence gastric cancer rate.Oleum Bulbus Allii has the anticancer interferon of generation in the body of stimulation simultaneously, increase anticancer and immunity, the activity that suppresses multiple harmful enzyme in the body, and enhance hepatocyte membrane stability, increase useful enzymatic activity, clinical experiment shows that Oleum Bulbus Allii can suppress and treat breast carcinoma, skin carcinoma, knot are opened intestinal cancer, rectal cancer, esophageal carcinoma, the generation of kinds of tumors such as hepatocarcinoma, lymphatic cancer.

4, antiviral: studies show that Bulbus Allii extract can be killed influenza virus B in external 0.15mg/ml concentration, 0.05mg/ml can kill herpes simplex virus.Bulbus Allii extract has inhibitory action to macrophage virus, it is reported, allicin can suppress the effect of HCMV cell death inducing.But one that is undertaken by the clinical virus research of attached Tongji University of hospital of Tongji University of Central China University of Science and Technology pediatric hospital at present studies show that, this effect of allicin shows as double effect, apoptosis for the macrophage virus induction, allicin has the obvious suppression effect, and its mechanism may be with relevant with the fas expression by disturbing HCMV to influence apoptosis controlling gene bc1-2.

5, diuresis: experiment shows, the anesthetized dog gastric is awarded garlic capsule, can produce the significantly diuresis relevant with dosage, natriuresis.

Bulbus Allii also has blood fat reducing in addition, and blood pressure lowering, blood sugar lowering, anticoagulant promote organism metabolism, protect the liver antithrombotic, arteriosclerosis, antioxidation, the anti-ageing effect of waiting for a long time.

(3) this product of Flos Lonicerae extract (jinyinhua extract) is the caprifoliaceae plant colored thunder of Radix Ophiopogonis, cold in nature, sweet in the mouth, has the bright poison of heat clearing away, the removing heat from blood phoenix that looses, and cures mainly anemopyretic cold, warm blood fulminant dysentery, erysipelas, effects such as epidemic febrile disease heating.

Chemical constituent: Flos Lonicerae mainly contains multiple chlorogenic acid chemical compound, as chlorogenic acid, and isochlorogenic acid, neochlorogenic acid, caffeic acid, rhinoceros element, volatilization wet goods.

Pharmacological action: pathogenic microorganism in 1, anti-: it is reported that Flos Lonicerae has in various degree inhibitory action external to multiple pathogenic bacteria, these antibacterials comprise staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus are because of the Bacillus typhi of the hot infection of intestinal acute heat that rises, viruses such as Salmonella paratyphi, escherichia coli, Amur dysentery bacterium, bacillus pyocyaneus, vibrio cholera, influenza virus.Flos Lonicerae can also strengthen the antibacterial effect of penicillin to the drug resistance staphylococcus aureus.For the tubercule bacillus Flos Lonicerae certain inhibitory action is arranged also.Discover that Flos Lonicerae has certain inhibitory action to oral cavity bacterium such as streptococcus.

2, antiviral: Flos Lonicerae has antivirus action, can suppress the 68-1 of the section strain of influenza virus capital, the cytopathic effect of arc virus and herpes simplex virus on the cell culture of human embryo kidney (HEK) layer upper strata of former generation; The Embryo Gallus domesticus test is done the simulation prevention before or after influenza virus, the treatment administration all can obviously suppress proliferation of influenza virus; Flos Lonicerae can also protect 68% influenza virus infection mice to avoid death; and journey dose-effect relationship ground suppresses influenza virus induced mice pneumonia; viral hemagglutinin tires and bronchioles inner virus specificity fluorescent granule in the obvious reduction infected mice lung; these results show honeysuckle aqueous extract in external, all show antiviral activity in the body.

3, antiendotoxin: Flos Lonicerae is the heat-clearing and toxic substances removing representative drugs, and except that resisting pathogenic microbes, microbial toxin also is a material base of " pyretic toxicity ".Experiment shows: Flos Lonicerae can obviously reduce the death of bacillus pyogenes endotoxin induced mice in the abdominal part injection, the quiet notes of its distillate have obvious antagonism to leukopenia and the shift to left of rabbit due to the bacillus pyocyaneus endotoxin, prepare injection by Flos Lonicerae, Radix Scutellariae, also can significantly alleviate the poisoning symptom of rabbit due to the bacillus pyocyaneus endotoxin, reduce mortality rate, The above results shows that the plain effect of the antibacterium of Flos Lonicerae may have certain meaning in the performance of its heat-clearing toxin-expelling functions.

4, antiinflammatory is analgesic: acute inflammation is an important behaviour of " pyretic toxicity ", Flos Lonicerae has significant antiinflammatory action, rat foot sole of the foot edema due to fresh Ovum Gallus domesticus album, the antler glue etc. can be obviously suppressed during drug administration by injection, inflammatory exudation and the inflammatory hyperplasia of Fructus Crotonis oiliness granulation capsule rat can also be obviously suppressed.Flos Lonicerae can promote the release of corticoid, and inflammation is had the obvious suppression effect.

Heating is another important behaviour of " pyretic toxicity " continuity, and Flos Lonicerae has refrigeration function, with the Flos Lonicerae be main preparation multiple compound recipe also tool significantly separate thermal effect.As Lonicerae and Forsythiae Powder, SHUANGHUANGLIAN injection, the analgesic compound recipe that YINHUANG ZHUSHEYE is formed.Generate heat to all having due to the living pyrogen EP in Lonicerae and Forsythiae Powder reaches endotoxin, yeast and significantly separate thermal effect.

5, improve immunity: the Flos Lonicerae decoct can promote lymphocyte transformation, the phagocytic activity of leukocyte increasing, inflammatory cell, extracting solution can significantly improve the scald macrophage phagocytosis of mice, improve the mouse liver Kupffer and remove the function of prepared Chinese ink, the anti-thick submission function of low macrophage is recovered.According to another report, can promote peripheral blood cells and mouse peritoneal inflammatory cell phagocytic activity in the in vivo test of Flos Lonicerae when external and intraperitoneal administration to foreign body.Chlorogenic acid, caffeic acid etc. have the cytosis of rising.

6, function of gallbladder promoting protects the liver: the contained abundant chlorogenic acid of Flos Lonicerae can be promoted rat bile secretion, the total Saponin subcutaneous injection of Lonicera fulvotnetosa Hsu et S. C. Cheng. Ms can significantly resist the assorted height of liver poisoning mice serum glutamate pyruvate transaminase due to carbon tetrachloride, acetaminophen and the D-galactosamine.Reduce content of triglyceride in the liver, obviously alleviate the hepatic pathology degree of injury.

Clinical effect: 1, treatment infectious disease, the merit of Flos Lonicerae heat-clearing and toxic substances removing is widely used in the various acute infectious disease, as flu, influenza, acute upper respiratory tract infection, pneumonia, acute bacillary dysentery, structure Leptospiral disease, acute skin infection etc.

(1) flu, influenza, upper respiratory tract infection:, this is had good curative effect based on the multiple compound recipe of Flos Lonicerae, control anemopyretic cold 1150 examples as Lonicerae and Forsythiae Powder brought down a fever in average 2.7 days, with the Lonicerae and Forsythiae Powder mixture, treatment acute upper respiratory tract infection 236 examples, 155 examples of bringing down a fever in 2 days after treating account for 82.4%, use YINQIAO powder, treatment acute upper respiratory tract sense 25 examples are cured 23 examples, and average fever time is 35 hours.

(2), pulmonary infection: it is reported honeysuckle flower injection treatment infantile pneumonia 25 examples, 16 examples of fully recovering, 9 examples take a turn for the better.Other has report, joins Radix Scutellariae with Flos Lonicerae and is Flos Lonicerae Radix Ophiopogonis electuary treatment infantile pneumonia 100 examples, cures 84 examples, sends out and changes 16 examples, the person's of bringing down a fever 44 examples in 2 days, the person's of bringing down a fever 20 examples in 3 days.

(3), acute bacillary dysentery: Flos Lonicerae compatibility Rhizoma Coptidis, Radix Scutellariae or compatibility purple garlic, Folium Camelliae sinensis, Radix Glycyrrhizae are treated 23 examples, and certain curative effect is arranged.

(4), leptospirosis: with Flos Lonicerae compatibility Fructus Forsythiae, the Flos Lonicerae mixture of Radix Scutellariae, treatment influenza typhoid fever type coupler body disease has than curative effect, and the patient is brought down a fever rapidly, doing well,improving and fully recovering.Join Herba Senecionis Scandentis and sick 109 examples of the golden ball injection made or tablet in treatment coupler body with Flos Lonicerae, wherein belong to influenza typhoid fever type 62 examples, pneumorrhagia type 38 examples, icterohemorrhagic form 8 examples, brain type 1 example, the state of an illness be than the lighter's 2 examples, moderate 49 examples, severe 25 examples, critical illness 14 examples, the result cures 101 examples, accounts for 96% dead 4 examples, heating person's 74 examples of bringing down a fever in 48 hours account for 85%.

Flos Lonicerae is treated the cutization pyogenic infection in addition in addition, and department of eye catches and the inflammation dermatosis.

(4), Radix Puerariae extract (Gegn extract), Radix Puerariae is the root of bean tannin plant Pueraria lobota.The property flat, sweet in the mouth, flat.Have relieving muscles diaphoresis, assorted positive rash, analgesic effect such as promote the production of body fluid.Modern pharmacological research thinks, be mainly used to the fever caused by exogenous pathogens headache, mouthful drink, disappear drink, measles without adequate eruption, hematodiarrhoea, have loose bowels, effect such as hypertension.

Chemical constituent: Radix Puerariae mainly contains puerarin, puerarin xyloside, big Glycine max (L.) Merr. cave, daidzin, Radix Puerariae alcohol, daidzin, Semen Glycines glycoside, glucoside, aminoacid, mineral matter and other components.

Pharmacological action: 1, antibiotic: the Radix Puerariae decoct is external inhibited to golden yellow coccus, shigella, Diplococcus pneumoniae.Experiment finds that this can be to suppress the dead mouse that Diplococcus pneumoniae and shigella cause in the body.

2, antiinflammatory enhance immunity effect: the GEGEN TANG extract powder can make rat alleviate because of chondrus ocellatus Holmes colloidality pedal swelling.GEGEN TANG can obviously strengthen Mouse Liver, splenic macrophage to the carbon granules capture functions, and is inhibited to the mice delayed pedal swelling reaction that the sheep cell brings out.GEGEN TANG can also make in the various granulocytes of In vitro culture CAMP concentration be dose dependent to rise, show anti-I type anaphylaxis effect is arranged, and can eliminate the immunologic tolerance of bringing out because of superfluous antigen sensibilization, can impel the cellular immune function reacting recovery of the dry thing processing of the lyophilizing back mice delayed hypersensitive reaction of tumor-bearing mice ascites supernatant.

3, analgesic: the Radix Puerariae infusion has the effect of remarkable reduction body temperature to the temperature thorn.Radix Puerariae preserved material oral administration has tangible refrigeration function to the fever in rabbit that the quiet notes of typhoid fever polyvalent vaccine cause.GEGEN QINLIAN TANG has tangible refrigeration function to the rat endotoxin-induced fever.

4, detoxifcation: Radix Puerariae can obviously improve decis and irritate hypertension and the arrhythmia that the intravenous LD of harmonization of the stomach also can anti-decis contamination dog, its mechanism of action may with its beta-receptor retardance, expanding cardiovascular and antiarrhythmic effect are relevant.

5, resisiting influenza virus infects: GEGEN TANG can suppress the cellular infiltration of influenza virus mice, pneumonia is alleviated, prolong survival time of mice, its mechanism makes and suppresses the inductive IL-1 α generation of IFN, regulate body to influenza and immunopathogenesis reaction, and not directly to the cytopathic effect of virus replication.

6, antitumor: the effective ingredient of Radix Puerariae daidzin is divided a word with a hyphen at the end of a line to people's acute promyelocytic leukemia cell strain HL-60 cell cycle and is G phase blocking effect, and G90 is increased, and S% descends, and shows that Radix Puerariae is a HL-60 cell-differentiation inducers effectively.Studies confirm that the Radix Puerariae daidzein has and significantly induces tumor necrosis factor (TNF) effect.GEGEN TANG can alleviate the toxic and side effects of anticarcinogen cisplatin to mice in addition.According to another report, daidzein can obviously suppress the melanoma B cell proliferation in the 10-20mg/ml concentration range.Radix Puerariae extract is to EC8 tumor, S ₁₈₀Tumor and pulmonary carcinoma all have certain inhibitory action.In addition Radix Puerariae also have blood pressure lowering, blood sugar lowering, blood fat reducing, protect the liver, arrhythmia, resist myocardial ischemia, coronary artery dilating, decreased heart rate, anticoagulant, improve ability of learning and memory, improve effects such as cerebral circulation, anti-hypoxia, antioxidation.

Clinical effect: 1, treatment fever caused by exogenous pathogens: Radix Puerariae cooperates Gypsum Fibrosum, Herba Ephedrae, Ramulus Cinnamomi treatment fever caused by exogenous pathogens 100 examples, effective percentage 96%.With Radix Puerariae Baihu Tang plus-minus treatment infantile hyperpyrexia, effect is remarkable.With the GEGEN TANG is main treatment fever of children 110 examples, and the result obeys 1 dose of body temperature and reduces to normal person's 66 examples.

Five, Radix Glycyrrhizae extract (Gancao extratc), this product is a leguminous plant intestinal Radix Glycyrrhizae, the dry root of Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. and foundation.The property flat, sweet in the mouth.Have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription, relieving spasm to stop pain effect.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, Guang abdomen, the anxious pain of extremity, cushion toxicity, strong, diarrhoea.

Chemical constituent: Radix Glycyrrhizae mainly contains glycyrrhizin, glycyrrhizic acid, enoxolone, liquiritin, the yellow glycoside of different glycerol, glycerol element, Angelica Polysaccharide, several amino acids, biotin, cupreol.

Pharmacological action: 1, antiinflammatory: glycyrrhizic acid that extracts in the Radix Glycyrrhizae extractum and enoxolone all have tangible antiinflammatory action.Radix Glycyrrhizae causes the auricle lump to mice dimethylbenzene, the acid toe swelling of chondrus ocellatus Holmes, and adjuvant-induced arthritis, the granuloma induced by implantation of cotton pellets active chronic inflammation all has antiphlogistic effects.Its mechanism is that glycyrrhizin produces antiinflammatory action by the one-tenth that inhibition neutrophilic leukocyte metabolism reduces active oxygen.

2, antibiotic parasite killing: glycyrol extract and Monosodium glycyrrhetin all have inhibitory action external to golden yellow coccus, tubercule bacillus, escherichia coli, ameba and infusorian.

3, raise immunity: Angelica Polysaccharide can make immune organ increase, and cleaning up of normal mouse vein carbon granules is significantly increased, and specificity and nonspecific immunity potentiation are arranged.Glycyrrhizic acid can promote the generation of Y-interferon and interleukin II, the cytoactive that strengthened NKT.Radix Glycyrrhizae crude extract Lx then has immunization, can suppress the immunoreation of macrophage, and it acts on macrophage and engulfs relevant enzyme, reduces the antigenic information amount and shows its immunosuppressive action.

4, antiviral: the enoxolone compounds strengthens the activity of natural killer cell and macrophage by direct effect and inducement interferon to multiple virion.Activate the indirect action of host immune function and bring into play the broad-spectrum disease resistance toxic action.

Angelica Polysaccharide is to vesicular stomatitis virus, and adenovirus III type, herpes simplex virus I-type and vaccinia virus all have the obvious suppression effect.Enoxolone can destroy invisible spectro AIDS virus (HIV), suppresses AIDS virus in external propagation.New Polyphenols in the Radix Glycyrrhizae of northwest demonstrates the proliferation inhibiting effect to HIV (human immunodeficiency virus) when low concentration.Enoxolone can strengthen the NK cytoactive, and enoxolone 5mg lumbar injection after one day, has tangible potentiation to spleen NK3 cell activity in mice, and the NK cytoactive in people's tip blood is also had similar effect.The Radix Glycyrrhizae acid amide also has the active effect of the NK cells in mice of raising.Report that in addition glycyrrhizin has the obvious suppression effect to B-mode, hepatitis C virus.Glycyrrhizin can also suppress SARS virus propagation.

5, analgesic calmness: enoxolone and glycyrrhizin all have refrigeration function to the rat and the mice of heating respectively.Enoxolone 1250mg/kg presents inhibitory action to central nervous system of mice, can cause calmness, hypnosis, body temperature reduction and respiration inhibition etc.

6, eliminating phlegm and stopping cough: the oral pharyngeal mucosa that can cover inflammation of Radix Glycyrrhizae extractum and licorice mixture, relax inflammatory stimulus, the performance antitussive action.Antitussive action of Radix Glycyrrhizae and antiinflammatory are irrelevant, and its antitussive effect produces by maincenter.After kinds of experiments confirms that the enoxolone choline is effective antisussive and expectorant agent.Radix Glycyrrhizae can also promote throat and bronchitis secretion, makes the easy expectoration of sputum, presents Antitussive and Expectorant Effect.

7, antitumor: glycyrrhizic acid, enoxolone and a series of derivant all have antitumor action in various degree, as rat gastric cancer, Mouse Liver ehrlich ascites carcinoma, mice Chinese mugwortization ehrlich ascites carcinoma, sarcoma etc.Its derivant also has anti-mouse leukemia effect.

8, detoxifcation: glycyrrhizin, glycyrrhizic acid, Radix Glycyrrhizae acid amide etc. all have Detoxication.Its effect is to precipitate, adsorb by physicochemical mode, and approach such as reinforcement liver detoxification function realize.Radix Glycyrrhizae and preparation thereof be to drug intoxication, alimentary toxicosis, and interior metabolism product is poisoned and bacteriocin all has certain Detoxication.Radix Glycyrrhizae can make Mouse Liver and plasma cell pigment P content obviously increase, and shows that liver drug enzyme is had inducing action, may be one of its detoxifcation mechanism.

9, protect the liver: Radix Glycyrrhizae fluidextract has obvious hepatoprotective effect to hepatic injury.Glycyrrhizin can obviously stop the rising of carbon tetrachloride poisoning rat glutamate pyruvate transaminase, can also reduce triglyceride in the liver, and the free radical that enoxolone can also the strong inhibition carbon tetrachloride and the generation of peroxidating matter suppress Ca and flow into caused primary cellular defect in the cell.

10, antioxidation: flavonoids of Glycyrrhiza can obviously suppress the malonaldehyde rising that mouse liver even slurry causes under the vibration incubation conditions, superoxide anion and hydroxy radical are had scavenging action, and its antagonism to lipid peroxidation and free radical is proved.One of its main component, liquorice chalcone have tangible lipoid peroxidization resistant, and hydroxy radical is had direct scavenging action.And the antitumaous effect of Radix Glycyrrhizae extract and antioxidation have certain relation.

In addition, Radix Glycyrrhizae also has the anti-multiple functions such as intestinal, gastric acid inhibitory, blood fat reducing, the sclerosis of anti-tremulous pulse sample, anticoagulant, arrhythmia, spasmolytic of bursting.

Six, Folium perillae extract (Zisuye extract), this product is the labiate Folium Perillae.Warm in nature, acrid in the mouth have the diaphoresis cold expelling, bring down a fever, effects such as promoting the circulation of QI to alleviate the stagnation in middle-JIAO.Be used for the treatment of effects such as cold, fever with aversion to cold, cough and asthma, breast abdominal distention.

Chemical constituent: from the Perilla plant, separate nearly hundred kinds of chemical constituents, be broadly divided into compositions such as algae, sterol, flavone and glycoside thereof, anthocyan, polysaccharide oils and fats.

Pharmacological action: 1, analgesic: the oral rabbit that the typhoid fever mixed vaccine is caused heating of Folium Perillae decoct and preserved material has refrigeration function.

2, raise immunity: the Folium Perillae ethanol extraction can strengthen the immunologic function of splenocyte, and ethanol extraction and perillaldehyde have immunosuppressive action.The hot water extract of Folium Perillae has the moderate inhibitory action to ConA and the inductive rat hypertrophy cell histamine release of chemical compound.The interferon inducers of Folium Perillae and stem system all confirms to have interferon activity in the experiment of spleen, bone marrow and the lymph node suspension of rabbit.

3, antimicrobial antiphlogistic: the common perilla leaf water decoct has inhibitory action to golden yellow coccus, and extractum also has inhibitory action to fungus.Perillaldehyde in the extractum, citral plays a major role.Alecrim acid in the Folium Perillae has antiinflammatory action.

4, cough-relieving, relieving asthma, eliminate the phlegm: Folium Perillae composition β-Flos Caryophylli alkene has relexation to guinea-pig isolated trachea, and the cough that acrylic aldehyde or the acid of structure rafter are caused has tangible antitussive effect, and the mice phenolsulfonphthalein test is positive; Linalool has antiasthmatic effect.Fructus Perillae has tangible prolongation effect to asthma due to the ethanol choline incubation period, can increase the phenol red excretion amount of trachea.

5, anticancer: the Folium Perillae aqueous extract can partly be blocked cancer thing Oleum Tiglii, the n-butyric acie synergy activates virus (EBV).Purple Soviet Union and green Folium Perillae also can obviously suppress the rising of the inductive blood serum tumor necrosin of mice.

Seven, herba houttuyniae (Gegen exracr) is the root herb of saururaceae plant houttuynia cordata.Cold nature, acrid in the mouth.Return lung meridian.Have heat-clearing and toxic substances removing, disappear the pain evacuation of pus, effects such as diuresis.Notes are controlled pneumonia, pulmonary abscess, urinary system infection, nephritis, otitis media, hematodiarrhoea, pyretic stranguria etc.

Chemical constituent: volatile oil, Quercetin, quercitrin, spun gold is chosen glycosides, rutin, edge ortho acid Palmic acid, potassium chloride, cordarine etc.

Pharmacological action: 1, antipathogen: external kinds of experiments shows that all herba houttuyniae is to multiple pathogenic bacteria mycobacteria, hook end spiral shell trip body, fungus and the viral inhibitory action that has in various degree.Cough bacillus and candida albicans, Cryptococcus histolyticus etc. as staphylococcus aureus, edge pus bacillus and dysentery bacterium, knot certain obviously inhibitory action is all arranged.Influenza virus also there is inhibitory action.Can also prolong the life span that infects the tubercule bacillus mice, reduce mortality rate.The antimicrobial effective ingredient of herba houttuyniae is a volatile oil.

2, antiinflammatory: the herba houttuyniae decoct can improve antalzyme activity and properdin level in leukocytic phagocytosis of chronic tracheitis patient and the blood in the external ability that the cytophagy staphylococcus aureus of obvious promotion is arranged.Foot swelling has significant antiinflammatory action to the herba houttuyniae decoct to rat formaldehyde, for people y-globulin at Cu ²⁺Declining property of heat under existing, herba houttuyniae also has the obvious suppression effect.According to another report, the Quercetin that herba houttuyniae is contained, flavone compounds such as quercitrin and Isoquercitrin also have significant antiinflammatory action, and significantly the early stage capillary permeability of inflammation-inhibiting is hyperfunction.

3, improve immunity: herba houttuyniae can strengthen the leukocytes phagocytic ability, improve the serum properdin, the herba houttuyniae injection can obviously improve rat periphery blood T lymphocyte and neutrophilic leukocyte phagocytic rate and spleen alloantibody cell formation rate, and herba houttuyniae can also significantly improve the male lymphocyte percentage ratio of peripheral blood α one acetic acid naphthalene fat in addition.

4, antiviral: herba houttuyniae decoct and extract are to first type capital, the influenza Asia 68-1 of section strain virus, Orphan virus, encephalomyocarditis virus, and herpesvirus II type all has inhibitory action.The herba houttuyniae extract has obvious prevention protective effect to the susceptible malicious mice infected of resurgent.

5, diuresis: the herba houttuyniae extract can make the animal telangiectasis, thereby blood flow and secretion of urine increase help diuresis.

6, antitumor: herba houttuyniae has certain antitumaous effect.The new herba houttuyniae element of mouse peritoneal injection various dose, its cancerous cell sum, cancerous cell segregation index, ascites volume all have obvious reduction, and the CAMP level all has and increases the inhibition effect also certain to mouse bearing liver cancer in the cancerous cell.

7, expelling phlegm for arresting cough: cough has inhibitory action to herba houttuyniae aqueous solution lumbar injection to the ammonia spraying induced mice.Quercetin then has preferably and eliminates the phlegm, antitussive action, also and certain antiasthmatic effect arranged.

Clinical effect: 1, acute respiratory infection: herba houttuyniae has better curative effect for the various acute infectious disease.For acute upper respiratory tract infection, acute/chronic bronchitis, bronchopneumonia, the scorching pneumonia of Da Ye and lung abscess better curative effect is arranged all.The compound recipe that herba houttuyniae and spire scented tea are formed mixture treatment with sweet and sour flavor fever caused by exogenous pathogens 660 examples obtain good efficacy.Report that in addition herba houttuyniae injection oral medication treating baby's cold is effective.It is rather good that herba houttuyniae extract for treating children's goes up sense 22 routine curative effects, and the plain curative effect of high concentration herba houttuyniae is treated respiratory inflammation 114 examples like better, and good curative effect is also arranged.So it is better with other heat and toxic materials clearing away medicine treatment curative effect of herba houttuyniae compatibility.In addition, synthetic herba houttuyniae element has become the common drug of chronic bronchitis, gets final product control infection, and certain enhancing immunity effect is arranged again.

For many types of pneumonia, herba houttuyniae also has curative effect preferably, as infantile pneumonia, and lobar pneumonia, organizing pneumonia, organized pneumonia.As with herba houttuyniae injection for treating lobar pneumonia 8 examples, wherein body temperature is in above person's 7 examples of 39 degree, behind the medicine all in 1-3 days temperature recovery normal, focus absorbed in average 12.8 days.It is also good that herba houttuyniae is joined Radix Platycodonis treatment lobar pneumonia curative effect.Report with herba houttuyniae treatment infantile pneumonia much has better curative effect, and with herba houttuyniae intramuscular injection suctions of penetrating or atomize, oral compound preparation or the synthetic herba houttuyniae element of single usefulness, the latter treats 91 examples, cures 72 examples, 12 examples that take a turn for the better, invalid 7 examples.

In addition, herba houttuyniae also has treatment department of eye inflammation, surgery and department of dermatologry infection or inflammation etc.

Eight, vitamin C (Vit C) has another name called and draws bad hematic acid.Vitamin C is a kind of multi-functional V, is the natural materials that extensively is present in fruit and the thin dish.Vitamin C is a white crystalline powder, has tangible tart flavour, and is soluble in water, should not process under high temperature and alkali condition.Vitamin C is a kind of simple six carbon compounds, and occurring in nature has two kinds of forms, i.e. reduced form ascorbic acid and oxidized form hydrogen ascorbic acid, and two all have physiologically active, all can be utilized by body.

Physiological function: 1, participate in biosynthesis, vitamin C in vivo in the digestion process cofactors as substrate and enzyme participate in multiple important biosynthetic process, comprise collagen protein, carnitine, the metabolism of the synthetic and cruel propylhomoserin of other neurotransmitter and peptide hormone etc., some enzyme require vitamin C could keep the activity of height.

2, raise immunity: vitamin C can promote prostaglandin and lymphocytic emiocytosis, be that body produces interferon and antitoxin, thereby play immunity and antivirus action, improve the control ability of body tissue, help to synthesize and to regulate the lymphocytic PGB 4 of T.Interferon is to be used for break virus to combine the maintenance white blood cell count with viral to reduce leukocyte.Raise immunity.

3, anti-flu: vitamin C is to constitute collagen protein, safeguards skin, the integrity of respiratory mucosa and robustness, sufficient vitamin C can help intravital cell and antibody, kill the invasion pathogenic microorganism, necessary a large amount of vitimin supplement C during therefore catching a cold are with enhancing immunity.

U.S. expert discovers that every day 1, gram left and right sides vitamin C can make flu descend 45%, and the course of disease shortens 60%, and vitamin C can be linked up respiratory apparatus and blood circulation promoting, and preventing respiratory infects, and increases the oxygen that body needs, and reduces flu and takes place.

4, anticancer: people's neutrophil can adsorb noxious bacteria, and is extremely important to prophylaxis of cancer.The neutrophil(e) cell inhales vitamin C; in the killing bacteria process, can produce oxidant; use the vitamin C antioxidant simultaneously, can protect the neutrophil vitamin C of not being damaged to hinder the synthetic of carcinogenic compound nitrosamine, prevent the generation of esophageal carcinoma, gastric cancer, hepatocarcinoma.Vitamin C also can improve the level of cell surface phosphoric acid gland etc., significantly reduces the probability of normal cell generation canceration, and can make slight cancerous tumor cell recover normal.

In addition, vitamin C also has the brain function of improvement except above-mentioned functions, resisting fatigue, cholesterol reducing, safeguards health of heart, protection cardiovascular and cerebrovascular vessel, The Maintenance Of Skin Health, antioxidation, the anti-ageing multiple function of waiting for a long time.

Nine, selenium (SE), selenium are a kind of electronegative nonmetallic ions.Be micro elements needed by human, be distributed widely in human body except that fat in a organized way in, with liver, pancreas, stomach, heart spleen and fingernail for the highest.Selenium concentration in the blood of human body differs.It is subjected to living environment, the influence of Se content in soil, water and the food, and selenium has multiple function in vivo.

Physiological function: 1, people's antioxidation, selenic antioxidation can be protected the integrity of cell membrane, removes free radical, defying age.Because human body cell contains a kind of unsaturated fatty acid, oxidation reaction takes place in containing the more tissue of oxygen easily, generate lipid peroxide.And lipid peroxide is accumulated in human body and can be caused physiological function to descend, and liver, lung, cardiovascular damage also quicken human senility speed simultaneously, and occurring as senile plaque is exactly the result of skin histology accumulation lipid peroxide.Selenium has the effect of decomposing lipid peroxide in vivo as the constituent of glutathione oxidase, thereby the protection biological cell is avoided destroying; keep the cell normal function; the protection body tissue is avoided free-radical oxidation and is destroyed, and removes free radical, thereby has defying age.

2, raise immunity: selenium has the lymphocyte of stimulation and immunoglobulin produces antibody, and the haematogenic immunity globulin levels is raise, and enhancing body produces the ability of antibody to vaccine or other antigen.Selenium can also strengthen lymphocyte transformation and delayed allergy, and lymphocyte is to mitogen irritant reaction ability drop when lacking selenium, and selenium supplement can promote cytophagous function.Therefore, selenium can improve human immunocyte and humoral immune function, and enhancing body is to the resistance of disease.Studies show that some old peoples take the enzyme preparation after 6 months that contains 100 micrograms every day, their immune full recovery is to young level.

3, antiviral: international current research shows, selenium is the nutrient that unique and viral infection have direct relation.An amount of Selenium Supplement can be prevented and the enantiopathy viral disease.Recently statistical data shows, when human body lacks selenium, infects the dangerous obviously increase of highly pathogenic viral disease.As influenza virus, cold virus, HIV (human immunodeficiency virus), smallpox virus and hepatovirus all have similar sensitivity to dye to lacking selenium.Selenium can promote T lymphocyte and neutrophilic granulocyte propagation and killing action, promotes the synthetic and antibody of immunoglobulin to generate, and the antiviral ability of enhancing body suppresses complement activation, alleviates the immunologic injury that immune complex causes.Selenium can also suppress the activation of HIV (human immunodeficiency virus), prevents apoptosis.U.S. Miami University studies have shown that the AIDSinfected patient that has optimum activity with selenoenzyme in the body is compared, and the mortality rate that lacks selenic AIDSinfected patient in the body will exceed more than 20 times.

4, cancer-resisting: selenium is the very capable trace element of anti-cancer.A large amount of experimental results show that, selenium has the differentiation of promotion and suppresses splitted two-way function cancerous cell, can also adjust the expression of propagation and split gene, make the cancerous cell behavior to normal conversion, simultaneously can suppress to change the activity of closely-related Protein kinase C with cancerous cell, thereby protein synthesis, dna replication dna and growth of cancer cells effectively in the anticancer.A large amount of clinical data checkings, the height of the blood selenium level of cancer patient is significantly positive negative correlation with pathogenesis of cancer.

New York the scholar prove, satisfying under the situation of nutritional need, replenishes 200 microgram selenium every day immunologic function is had significant stimulation, and the growing amount of T lymphocyte and neutrophilic granulocyte can roll up.This bacteriostatic has tumoricidal effect.According to Epidemiological study, selenium supplement can reduce carcinoma of prostate, and having an effect of pulmonary carcinoma and hepatocarcinoma is the most obvious.

The anti-cancer experiment that University of Arizona carries out shows, take every day among the crowd of 200 microgram selenium preparations, the cancer general mortality rate reduces by 50%, total incidence reduces by 37%, the sickness rate of carcinoma of prostate reduces by 63%, and the colon cancer sickness rate has reduced by 53%, and the lung cancer morbidity rate reduces by 46%, especially when beginning to experimentize to after the minimum people's Selenium Supplement of selenium concentration in the body, this antitumaous effect is more obvious.

5, eliminate heavy metal of body: selenium is a kind of electronegative nonmetallic ion, can combine with the metal ion of positively charged load in human body, and metal ions such as the aluminum that brings out virus, hydrargyrum, copper are excreted.

In addition, selenium also has protection cardiovascular, liver and eyes and improves multiple function such as diabetic symptom.

In sum, this capsule tool antiviral, infection, anti-ly cure cold, multiple functions such as influenza virus, antiinflammatory are analgesic, human body immunity improving function.

Processing technology: 1, mixing preparation: elder generation mixes Echinacea extract, Bulbus Allii extract, Flos Lonicerae extract, Radix Puerariae extract, Radix Glycyrrhizae extract, Folium perillae extract, herba houttuyniae extract, vitamin C, selenium and fully stirs.

2, capsule is filled: with the raw material that stirs, send into and fill and raw material is filled in the capsule.

3, seal: populated capsule is sealed by standard.

4, test package: with the capsule sealed through after the assay was approved, pack formal product.Mixing stirring is with after all raw materials mix in the component design, and the operation that stirs, and this operation gets the formula material mixture.It is that the mixed material that preceding operation makes is filled in operation in the capsule that capsule is filled.Sealing process is the process that the capsule that preceding operation is populated seals.This operation is in order to prevent that the material composition in the filled capsules from leaking, and this operation gets the semi-finished product capsule.Test package is to seal the chewing gum capsule by state quality standard, and after the assay was approved, packing becomes the operation of formal product.

Six, quality standard

1, theory index:

Echinacea extract g/100g 17.4

Bulbus Allii extract g/100g 13.1

Flos Lonicerae extract g/100g 15.2

Radix Puerariae extract g/100g 10.9

Radix Glycyrrhizae extract g/100g 10.9

Folium perillae extract g/100g 10.9

Herba houttuyniae extract g/100g 8.7

Vitamin C g/100g 13.1

Selenium mg/100g 3.3

2, instructions of taking: every day three times, each 0.5 gram-10 grams, the child all subtracts.

Seven, the specific embodiment:

Embodiment: get 40 kilograms of Echinacea extracts, 35 kilograms of Flos Lonicerae extracts, 30 kilograms of Bulbus Allii extracts, 35 kilograms of Radix Puerariae extracts, 25 kilograms of Folium perillae extract, 25 kilograms of Radix Glycyrrhizae extracts, 20 kilograms of herba houttuyniae extracts, 30 kilograms of vitamin Cs, 7.5 milligrams on selenium.

Earlier with Echinacea extract, Flos Lonicerae extract, Bulbus Allii extract, Radix Puerariae extract, Folium perillae extract, Radix Glycyrrhizae extract, VC, selenium, mix and stir and send into filling machine, then uniform raw material is filled in the capsule, material composition in capsule leaks, capsule is sealed, this operation gets the semi-finished product capsule, and by state quality standard after the assay was approved, packing becomes formal product.

Claims (2)

1, the virus-clearing capsule processing technology is: mixing is stirred, capsule is filled, capsule seals, and test package gets formal product.

2, process conditions are 40 kilograms of Echinacea extracts, 35 kilograms of Flos Lonicerae extracts, 30 kilograms of Bulbus Allii extracts, 25 kilograms of Radix Puerariae extracts, 25 kilograms of Folium perillae extract, 25 kilograms of Radix Glycyrrhizae extracts, 20 kilograms of herba houttuyniae extracts, 30 kilograms of vitamin Cs, 7.5 milligrams on selenium etc.The allotment mixing is gone forward side by side and is stirred, and sends into filling machine raw material is filled in the capsule.Then capsule is sealed, be up to the standards, packing becomes formal product.