CN1857596A - Cancer treating medicine composition and its preparing method - Google Patents
Cancer treating medicine composition and its preparing method Download PDFInfo
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- CN1857596A CN1857596A CNA2006100664582A CN200610066458A CN1857596A CN 1857596 A CN1857596 A CN 1857596A CN A2006100664582 A CNA2006100664582 A CN A2006100664582A CN 200610066458 A CN200610066458 A CN 200610066458A CN 1857596 A CN1857596 A CN 1857596A
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Abstract
The present invention discloses a kind of cancer treating medicine composition and its preparation process. The medicine composition is prepared with 36 kinds of Chinese medicinal materials, including forsythia, honeysuckle, angelica, skullcap root, dahurian angelica root. It has obvious curative effect and low cost.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of cancer and preparation method thereof.
Background technology
Cancer originates from the malignant tumor of epithelial tissue in the human body, and the malignant tumor that originates from mesenchymal tissue is interior tumor, and cancer and interior tumor all have some features of malignant tumor, and this two classes tumor all is called cancer.Cancer is human maximum killer of 21 century, has seized countless life, is nowadays still continuing to threaten the mankind.The cancer of China is sent out rate and is risen year by year, is just entering the high-incidence season of cancer, and cancer has risen to the first place of the various diseases cause of the death.The inventor sees increasing of carninomatosis people on every side, and is high to the large hospital medical expense, and the patient of a lot of low incomes can not accept high medical expenses, life in spite of illness, and one day seems like a year, and psychosoma is subjected to serious torment and wrecks.Clinical practice experimentation of the present invention, strictness are followed theory of Chinese medical science " monarch ", through the clinical observation of hundreds and thousands of examples, work out the pharmaceutical composition of treatment cancer.Pharmaceutical composition expense of the present invention is low, and the patient of high and low income can both be accepted, and removed to the large hospital radiotherapy chemotherapy high expense of being in hospital, and effect is remarkable.
Summary of the invention
The object of the invention is to provide a kind of has remarkable result and the cheap pharmaceutical composition of expense to the treatment cancer.
Another object of the present invention is to provide a kind of preparation of drug combination method for the treatment of cancer.
The present invention is achieved through the following technical solutions: choose crude drug
Fructus Forsythiae 7-23 weight portion Flos Lonicerae 15-45 weight portion Radix Angelicae Sinensis 7-23 weight portion
Radix Scutellariae 6-18 weight portion Radix Angelicae Dahuricae 6-18 weight portion Radix Paeoniae Rubra 7-23 weight portion
Gekko Swinhonis 0.15-0.45 weight portion Venenum Bufonis 0.02-0.08 weight portion Radix Notoginseng 6-18 weight portion
Fructus Akebiae 7-23 weight portion Fructus Mume 6-18 weight portion Semen Trichosanthis 15-45 weight portion
Rhizoma Cimicifugae 15-45 weight portion Rhizoma Paridis 6-18 weight portion Radix Astragali 15-45 weight portion
Mylabris 0.2-0.4 weight portion Scorpio 4-14 weight portion Bulbus Fritillariae Uninbracteatae 6-18 weight portion
Herba Lobeliae Chinensis 7-23 weight portion Concha Arcae 7-23 weight portion Herba Hedyotidis Diffusae 15-45 weight portion
Rhizoma Dioscoreae Bulbiferae 5-15 weight portion Semen Strychni 0.4-1.4 weight portion Fructus Crataegi 15-45 weight portion
Bombyx Batryticatus 15-45 weight portion Scolopendra 3-9 weight portion Nidus Vespae 2-8 weight portion
Agkistrodon 1.5-4.5 weight portion Poria 10-30 weight portion Radix Saposhnikoviae 7-23 weight portion
Rhizoma Chuanxiong 5-15 weight portion Thallus Laminariae (Thallus Eckloniae) 7-23 weight portion Cortex Eucommiae 6-18 weight portion
Herba Cistanches 7-23 weight portion Radix Fissistigmatis Glaucescentis 15-45 weight portion Rhizoma Pinelliae 6-18 weight portion
The optimum ratio of the present composition is: choose crude drug
Fructus Forsythiae 15 weight portion Flos Loniceraes 30 weight portion Radix Angelicae Sinensis 15 weight portions
The Radix Scutellariae 12 weight portion Radixs Angelicae Dahuricae 12 weight portion Radix Paeoniae Rubra 15 weight portions
Gekko Swinhonis 0.3 weight portion Venenum Bufonis 0.05 weight portion Radix Notoginseng 12 weight portions
Fructus Akebiae 15 weight portion Fructus Mume 12 weight portion Semen Trichosanthiss 30 weight portions
The Rhizoma Cimicifugae 30 weight portion Rhizoma Paridis 12 weight portion Radixs Astragali 30 weight portions
Mylabris 0.03 weight portion Scorpio 9 weight portion Bulbus Fritillariae Uninbracteataes 12 weight portions
Herba Lobeliae Chinensis 15 weight portion Concha Arcaes 15 weight portion Herba Hedyotidis Diffusaes 30 weight portions
Rhizoma Dioscoreae Bulbiferae 10 weight portion Semen Strychnis 0.9 weight portion Fructus Crataegi 30 weight portions
Bombyx Batryticatus 30 weight portion Scolopendras 6 weight portion Nidus Vespaes 5 weight portions
Agkistrodon 3 weight portion Poria 20 weight portion Radix Saposhnikoviaes 15 weight portions
The Rhizoma Chuanxiong 10 weight portion Thallus Laminariae (Thallus Eckloniae)s 15 weight portion Cortexs Eucommiae 12 weight portions
The Herba Cistanches 15 weight portion Radix Fissistigmatis Glaucescentiss 30 weight portion Rhizoma Pinelliaes 12 weight portions
Described Semen Strychni is a Semen Strychni (processed).
Preparation of drug combination method of the present invention is following steps:
1, Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder;
2, Gekko Swinhonis with 0.5-1.5 weight portion rice fry to sallow, grind into fine powder;
3, Mylabris head, foot, wing are removed, put into the oven dry of 0.5-1.5 weight portion Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product;
4, with the fine powder mix homogeneously of above-mentioned steps 1,2 and 3;
5, again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 3-9 hour with pure water 500-1500 weight portion, with slow fire boiling 0.5-1.5 hour, the reuse big fire decocted 20-60 minute, filter and remove residue, concentrate, put into the medicated powder mixing of above-mentioned steps 4, add conventional adjuvant and make tablet, granule, pill, capsule.
Preparation of drug combination method of the present invention is following steps:
1, Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder;
2, Gekko Swinhonis with 1 weight portion rice fry to sallow, grind into fine powder;
3, Mylabris head, foot, wing are removed, put into the oven dry of 1 weight portion Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product;
4, with the fine powder mix homogeneously of above-mentioned steps 1,2 and 3;
5, again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 6 hours with pure water 1000 weight portions, with slow fire boiling 1 hour, the reuse big fire decocted 40 minutes, filter and remove residue, be concentrated into the 230-670 weight portion, add the Mel of 130-390 and the dextrin of 180-540, put into the medicated powder mixing pill of above-mentioned steps 4 again, oven dry, polishing are promptly.
Drug regimen of the present invention adds any dosage form that conventional adjuvant can be made into clinical acceptance.
Described dosage form is tablet, capsule, a material agent, pill, emplastrum, ointment, spray etc.
Pharmaceutical composition of the present invention has that the liver of helping spleen lung kidney is promoted blood circulation, the effect of compensate qi and blood negative and positive, hard masses softening and resolving pain relieving, blood circulation and promoting silt detumescence, the hemopoietic of invigorating blood circulation detoxifcation, clearing away heat and cooling blood voltage stabilizing, to multiple malignant tumor such as treatment esophageal carcinoma, gastric cancer, hepatocarcinoma, pulmonary carcinoma, uterus carcinoma, rectal cancer, breast carcinoma, cancer of pancreas, carcinoma of gastric cardia, leukemia, effect is remarkable.Present composition expense is low, and the patient of high and low income can both be accepted, and removed to the large hospital radiotherapy chemotherapy high expense of being in hospital, and effect is remarkable.
The invention will be further described below in conjunction with experimental example:
1. clinical observation
Pharmaceutical composition of the present invention is from 1986 to 2005 treatment cancer patient 121 examples, male's 74 examples wherein, women's 47 examples, maximum 67 years old age, minimal ages 38 years old, 52 years old mean age, course of disease 1-3 month 42 examples, 3-6 month 57 examples, 18 examples in 6 months-1 year half, 4 examples in 1 year-2 years.
2. diagnostic criteria
Clinical observation 121 routine patients of the present invention all confirm as cancer at large hospital by CT or nuclear magnetic resonance, NMR or ultrasonic doppler examination.
3. Therapeutic Method
3.1 prescription: Fructus Forsythiae 15g, Flos Lonicerae 30g, Radix Angelicae Sinensis 15g, Radix Scutellariae 12g, Radix Angelicae Dahuricae 12g, Radix Paeoniae Rubra 15g, Gekko Swinhonis 0.3g, Venenum Bufonis 0.05g, Radix Notoginseng 12g, Fructus Akebiae 15g, Fructus Mume 12g, Semen Trichosanthis 30g, Rhizoma Cimicifugae 30g, Rhizoma Paridis 12g, Radix Astragali 30g, Mylabris 0.03g, Scorpio 9g, Bulbus Fritillariae Uninbracteatae 12g, Herba Lobeliae Chinensis 15g, Concha Arcae 15g, Herba Hedyotidis Diffusae 30g, Rhizoma Dioscoreae Bulbiferae 10, Semen Strychni (system) 0.9g, Fructus Crataegi 30g, Bombyx Batryticatus 30g, Scolopendra 6g, Nidus Vespae 5g, Agkistrodon 3g, Poria 20g, Radix Saposhnikoviae 15g, Rhizoma Chuanxiong 10g, Thallus Laminariae (Thallus Eckloniae) 15g, Cortex Eucommiae 12g, Herba Cistanches 15g, Radix Fissistigmatis Glaucescentis 30g, Rhizoma Pinelliae 12g.
3.2 preparation technology
Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder; Gekko Swinhonis with 1g rice fry to sallow, grind into fine powder; Mylabris head, foot, wing are removed, put into the oven dry of 1g Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product; With above-mentioned all medicated powder mix homogeneously; Again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 6 hours with pure water 1000g, with slow fire boiling 1 hour, the reuse big fire decocted 40 minutes, filter and remove residue, be concentrated into 450g, add the Mel of 260g and the dextrin of 360g, put into above-mentioned all medicated powder mixing pills again, oven dry, polishing are promptly.
3.3 instructions of taking
Pill of the present invention is taken three times every day, each 3-6g, and take one hour ante cibum, 50 days courses of treatment.
4, criterion of therapeutical effect
Cure: by nuclear magnetic resonance check or CT examination or ultrasonic doppler examination, cancer-free cell.
Effectively: by nuclear magnetic resonance check or CT examination or ultrasonic doppler examination, cancerous cell reduces.
Invalid: as not have obvious change by nuclear magnetic resonance check or CT examination or ultrasonic doppler examination cancerous cell.
5, therapeutic outcome
Present composition clinical observation 121 routine cancer patients cure 117 examples, and cure rate is 95%.
6, model case
Case 1: Zhao * *, man, 67 years old now, suffer from breast cancer with nuclear magnetic resonance check through county institute of traditional Chinese medicine, do not heal in the county hospital, taken pill of the present invention in April, 2005, takes every day three times, each 3-6g, take one hour ante cibum, and program 50 days is fully recovered after taking 3 courses of treatment, medicine is suited the medicine to the illness, and expense only needs 530 yuan.
Case 2: old * *, the man, 38 years old, suffered from hepatocarcinoma mid-term through county doctor ultrasonic doppler examination June calendar year 2001, takes pill of the present invention, take every day three times, each 3-6g, take one hour ante cibum, program 50 days, 7 recoveries from illness courses of treatment.
Case 3: be * *, the man, 51 years old is rectal cancer through county institute of traditional Chinese medicine with nuclear magnetic resonance check, take bolus of drug of the present invention in July, 2002, takes every day three times, each 3-6g, take one hour ante cibum, program 50 days, 4 recoveries from illness courses of treatment.
Case 4: make pottery * *, the man, 65 years old now is pulmonary carcinoma through county institute of traditional Chinese medicine with nuclear magnetic resonance check, takes the present invention in 2003, takes every day three times, each 3-6g, take one hour ante cibum, program 50 days, fully recover 8 courses of treatment.
Case 5: Zhu * *, the man, 67 years old now, through county institute of traditional Chinese medicine with nuclear magnetic resonance check for getting a cancer of the stomach, take medicine of the present invention in February, 2005, takes every day three times, each 3-6g, take one hour ante cibum, program 50 days, 4 recoveries from illness courses of treatment.
Case 6: open *, the woman, 49 years old now, in the county hospital CT examination, suffer from breast cancer, take medicine of the present invention, take every day three times, each 3-6g, take one hour ante cibum, program 50 days, 2 recoveries from illness courses of treatment.
Following embodiment is used to further specify the present invention:
The specific embodiment
Embodiment 1:
Fructus Forsythiae 15kg Flos Lonicerae 30kg Radix Angelicae Sinensis 15kg Radix Scutellariae 12kg
Radix Angelicae Dahuricae 12kg Radix Paeoniae Rubra 15kg Gekko Swinhonis 0.3kg Venenum Bufonis 0.05kg
Radix Notoginseng 12kg Fructus Akebiae 15kg Fructus Mume 12kg Semen Trichosanthis 30kg
Rhizoma Cimicifugae 30kg Rhizoma Paridis 12kg Radix Astragali 30kg Mylabris 0.03kg
Scorpio 9kg Bulbus Fritillariae Uninbracteatae 12kg Herba Lobeliae Chinensis 15kg Concha Arcae 15kg
Herba Hedyotidis Diffusae 30kg Rhizoma Dioscoreae Bulbiferae 10kg Semen Strychni 0.9kg Fructus Crataegi 30kg
Bombyx Batryticatus 30kg Scolopendra 6kg Nidus Vespae 5kg Agkistrodon 3kg
Poria 20kg Radix Saposhnikoviae 15kg Rhizoma Chuanxiong 10kg Thallus Laminariae (Thallus Eckloniae) 15kg
Cortex Eucommiae 12kg Herba Cistanches 15kg Radix Fissistigmatis Glaucescentis 30kg Rhizoma Pinelliae 12kg
Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder; Gekko Swinhonis with 1g rice fry to sallow, grind into fine powder; Mylabris head, foot, wing are removed, put into the oven dry of 1g Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product; With above-mentioned all medicated powder mix homogeneously; Again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 6 hours with pure water 1000g, with slow fire boiling 1 hour, the reuse big fire decocted 40 minutes, filter and remove residue, be concentrated into 450g, add the Mel of 260g and the dextrin of 360g, put into above-mentioned all medicated powder mixings again and make pill, oven dry, polishing are promptly.Take every day three times, each 3～6g, take one hour ante cibum, program 50 days.
Embodiment 2:
Fructus Forsythiae 10kg Flos Lonicerae 40kg Radix Angelicae Sinensis 10kg Radix Scutellariae 15kg
Radix Angelicae Dahuricae 9kg Radix Paeoniae Rubra 20kg Gekko Swinhonis 0.2kg Venenum Bufonis 0.07kg
Radix Notoginseng 9kg Fructus Akebiae 20kg Fructus Mume 9kg Semen Trichosanthis 40kg
Rhizoma Cimicifugae 20kg Rhizoma Paridis 15kg Radix Astragali 20kg Mylabris 0.4kg
Scorpio 6kg Bulbus Fritillariae Uninbracteatae 15kg Herba Lobeliae Chinensis 10kg Concha Arcae 20kg
Herba Hedyotidis Diffusae 20kg Rhizoma Dioscoreae Bulbiferae 13kg Semen Strychni 0.6kg Fructus Crataegi 40kg
Bombyx Batryticatus 20kg Scolopendra 8kg Nidus Vespae 3kg Agkistrodon 4kg
Poria 15kg Radix Saposhnikoviae 20kg Rhizoma Chuanxiong 7kg Thallus Laminariae (Thallus Eckloniae) 20kg
Cortex Eucommiae 9kg Herba Cistanches 20kg Radix Fissistigmatis Glaucescentis 20kg Rhizoma Pinelliae 15kg
Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder; Gekko Swinhonis with 1g rice fry to sallow, grind into fine powder; Mylabris head, foot, wing are removed, put into the oven dry of 1.2g Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product; With above-mentioned all medicated powder mix homogeneously; Again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 7 hours with pure water 1200g, with slow fire boiling 1.2 hours, the reuse big fire decocted 50 minutes, filter and remove residue, be concentrated into 500g, add conventional adjuvant and make capsule.
Embodiment 3:
Fructus Forsythiae 20kg Flos Lonicerae 20kg Radix Angelicae Sinensis 20kg Radix Scutellariae 9kg
Radix Angelicae Dahuricae 15kg Radix Paeoniae Rubra 10kg Gekko Swinhonis 0.4kg Venenum Bufonis 0.03kg
Radix Notoginseng 15kg Fructus Akebiae 10kg Fructus Mume 15kg Semen Trichosanthis 20kg
Rhizoma Cimicifugae 40kg Rhizoma Paridis 9kg Radix Astragali 40kg Mylabris 0.2kg
Scorpio 12kg Bulbus Fritillariae Uninbracteatae 9kg Herba Lobeliae Chinensis 20kg Concha Arcae 10kg
Herba Hedyotidis Diffusae 40kg Rhizoma Dioscoreae Bulbiferae 7kg Semen Strychni 1.2kg Fructus Crataegi 20kg
Bombyx Batryticatus 40kg Scolopendra 4kg Nidus Vespae 7kg Agkistrodon 2kg
Poria 25kg Radix Saposhnikoviae 10kg Rhizoma Chuanxiong 13kg Thallus Laminariae (Thallus Eckloniae) 10kg
Cortex Eucommiae 16kg Herba Cistanches 10kg Radix Fissistigmatis Glaucescentis 40kg Rhizoma Pinelliae 8kg
Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder; Gekko Swinhonis with 1g rice fry to sallow, grind into fine powder; Mylabris head, foot, wing are removed, put into the oven dry of 0.8 Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product; With above-mentioned all medicated powder mix homogeneously; Again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 5 hours with pure water 800g, with slow fire boiling 0.8 hour, the reuse big fire decocted 30 minutes, filter and remove residue, be concentrated into 400g, add conventional adjuvant and make tablet.
Embodiment 4:
Fructus Forsythiae 15kg Flos Lonicerae 30kg Radix Angelicae Sinensis 15kg Radix Scutellariae 12kg
Radix Angelicae Dahuricae 12kg Radix Paeoniae Rubra 15kg Gekko Swinhonis 0.3kg Venenum Bufonis 0.05kg
Radix Notoginseng 12kg Fructus Akebiae 15kg Fructus Mume 12kg Semen Trichosanthis 30kg
Rhizoma Cimicifugae 30kg Rhizoma Paridis 12kg Radix Astragali 30kg Mylabris 0.03kg
Scorpio 9kg Bulbus Fritillariae Uninbracteatae 12kg Herba Lobeliae Chinensis 15kg Concha Arcae 15kg
Herba Hedyotidis Diffusae 30kg Rhizoma Dioscoreae Bulbiferae 10kg Semen Strychni 0.9kg Fructus Crataegi 30kg
Bombyx Batryticatus 30kg Scolopendra 6kg Nidus Vespae 5kg Agkistrodon 3kg
Poria 20kg Radix Saposhnikoviae 15kg Rhizoma Chuanxiong 10kg Thallus Laminariae (Thallus Eckloniae) 15kg
Cortex Eucommiae 12kg Herba Cistanches 15kg Radix Fissistigmatis Glaucescentis 30kg Rhizoma Pinelliae 12kg
Said medicine technology routinely adds conventional adjuvant and makes emplastrum.
Claims (10)
1, a kind of pharmaceutical composition for the treatment of cancer is characterized in that said composition is to be made by following crude drug:
Fructus Forsythiae 7-23 weight portion Flos Lonicerae 15-45 weight portion Radix Angelicae Sinensis 7-23 weight portion
Radix Scutellariae 6-18 weight portion Radix Angelicae Dahuricae 6-18 weight portion Radix Paeoniae Rubra 7-23 weight portion
Gekko Swinhonis 0.15-0.45 weight portion Venenum Bufonis 0.02-0.08 weight portion Radix Notoginseng 6-18 weight portion
Fructus Akebiae 7-23 weight portion Fructus Mume 6-18 weight portion Semen Trichosanthis 15-45 weight portion
Rhizoma Cimicifugae 15-45 weight portion Rhizoma Paridis 6-1.8 weight portion Radix Astragali 15-45 weight portion
Mylabris 0.2-0.4 weight portion Scorpio 4-14 weight portion Bulbus Fritillariae Uninbracteatae 6-18 weight portion
Herba Lobeliae Chinensis 7-23 weight portion Concha Arcae 7-23 weight portion Herba Hedyotidis Diffusae 15-45 weight portion
Rhizoma Dioscoreae Bulbiferae 5-15 weight portion Semen Strychni 0.4-1.4 weight portion Fructus Crataegi 15-45 weight portion
Bombyx Batryticatus 15-45 weight portion Scolopendra 3-9 weight portion Nidus Vespae 2-8 weight portion
Agkistrodon 1.5-4.5 weight portion Poria 10-30 weight portion Radix Saposhnikoviae 7-23 weight portion
Rhizoma Chuanxiong 5-15 weight portion Thallus Laminariae (Thallus Eckloniae) 7-23 weight portion Cortex Eucommiae 6-18 weight portion
Herba Cistanches 7-23 weight portion Radix Fissistigmatis Glaucescentis 15-45 weight portion Rhizoma Pinelliae 6-18 weight portion.
2, pharmaceutical composition according to claim 1 is characterized in that said composition is to be made by following crude drug:
Fructus Forsythiae 15 weight portion Flos Loniceraes 30 weight portion Radix Angelicae Sinensis 15 weight portions
The Radix Scutellariae 12 weight portion Radixs Angelicae Dahuricae 12 weight portion Radix Paeoniae Rubra 15 weight portions
Gekko Swinhonis 0.3 weight portion Venenum Bufonis 0.05 weight portion Radix Notoginseng 12 weight portions
Fructus Akebiae 15 weight portion Fructus Mume 12 weight portion Semen Trichosanthiss 30 weight portions
The Rhizoma Cimicifugae 30 weight portion Rhizoma Paridis 12 weight portion Radixs Astragali 30 weight portions
Mylabris 0.03 weight portion Scorpio 9 weight portion Bulbus Fritillariae Uninbracteataes 12 weight portions
Herba Lobeliae Chinensis 15 weight portion Concha Arcaes 15 weight portion Herba Hedyotidis Diffusaes 30 weight portions
Rhizoma Dioscoreae Bulbiferae 10 weight portion Semen Strychnis 0.9 weight portion Fructus Crataegi 30 weight portions
Bombyx Batryticatus 30 weight portion Scolopendras 6 weight portion Nidus Vespaes 5 weight portions
Agkistrodon 3 weight portion Poria 20 weight portion Radix Saposhnikoviaes 15 weight portions
The Rhizoma Chuanxiong 10 weight portion Thallus Laminariae (Thallus Eckloniae)s 15 weight portion Cortexs Eucommiae 12 weight portions
The Herba Cistanches 15 weight portion Radix Fissistigmatis Glaucescentiss 30 weight portion Rhizoma Pinelliaes 12 weight portions.
3, pharmaceutical composition according to claim 1 is characterized in that said composition is to be made by following crude drug:
Fructus Forsythiae 10 weight portion Flos Loniceraes 40 weight portion Radix Angelicae Sinensis 10 weight portions
The Radix Scutellariae 15 weight portion Radixs Angelicae Dahuricae 9 weight portion Radix Paeoniae Rubra 20 weight portions
Gekko Swinhonis 0.2 weight portion Venenum Bufonis 0.07 weight portion Radix Notoginseng 9 weight portions
Fructus Akebiae 20 weight portion Fructus Mume 9 weight portion Semen Trichosanthiss 40 weight portions
The Rhizoma Cimicifugae 20 weight portion Rhizoma Paridis 15 weight portion Radixs Astragali 20 weight portions
Mylabris 0.4 weight portion Scorpio 6 weight portion Bulbus Fritillariae Uninbracteataes 15 weight portions
Herba Lobeliae Chinensis 10 weight portion Concha Arcaes 20 weight portion Herba Hedyotidis Diffusaes 20 weight portions
Rhizoma Dioscoreae Bulbiferae 13 weight portion Semen Strychnis 0.6 weight portion Fructus Crataegi 40 weight portions
Bombyx Batryticatus 20 weight portion Scolopendras 8 weight portion Nidus Vespaes 3 weight portions
Agkistrodon 4 weight portion Poria 15 weight portion Radix Saposhnikoviaes 20 weight portions
The Rhizoma Chuanxiong 7 weight portion Thallus Laminariae (Thallus Eckloniae)s 20 weight portion Cortexs Eucommiae 9 weight portions
The Herba Cistanches 20 weight portion Radix Fissistigmatis Glaucescentiss 20 weight portion Rhizoma Pinelliaes 15 weight portions.
4, pharmaceutical composition according to claim 1 is characterized in that said composition is to be made by following crude drug:
Fructus Forsythiae 20 weight portion Flos Loniceraes 20 weight portion Radix Angelicae Sinensis 20 weight portions
The Radix Scutellariae 9 weight portion Radixs Angelicae Dahuricae 15 weight portion Radix Paeoniae Rubra 10 weight portions
Gekko Swinhonis 0.4 weight portion Venenum Bufonis 0.03 weight portion Radix Notoginseng 15 weight portions
Fructus Akebiae 10 weight portion Fructus Mume 15 weight portion Semen Trichosanthiss 20 weight portions
The Rhizoma Cimicifugae 40 weight portion Rhizoma Paridis 9 weight portion Radixs Astragali 40 weight portions
Mylabris 0.2 weight portion Scorpio 12 weight portion Bulbus Fritillariae Uninbracteataes 9 weight portions
Herba Lobeliae Chinensis 20 weight portion Concha Arcaes 10 weight portion Herba Hedyotidis Diffusaes 40 weight portions
Rhizoma Dioscoreae Bulbiferae 7 weight portion Semen Strychnis 1.2 weight portion Fructus Crataegis 20 weight portions
Bombyx Batryticatus 40 weight portion Scolopendras 4 weight portion Nidus Vespaes 7 weight portions
Agkistrodon 2 weight portion Poria 25 weight portion Radix Saposhnikoviaes 10 weight portions
The Rhizoma Chuanxiong 13 weight portion Thallus Laminariae (Thallus Eckloniae)s 10 weight portion Cortexs Eucommiae 16 weight portions
The Herba Cistanches 10 weight portion Radix Fissistigmatis Glaucescentiss 40 weight portion Rhizoma Pinelliaes 8 weight portions.
5,, it is characterized in that described Semen Strychni is a Semen Strychni(processed) according to the described pharmaceutical composition of one of claim 1-4.
6, preparation of drug combination method according to claim 5 is characterized in that preparation method is to be following steps:
1). Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder;
2). Gekko Swinhonis with 0.5-1.5 weight portion rice fry to sallow, grind into fine powder;
3). Mylabris head, foot, wing are removed, put into the oven dry of 0.5-1.5 weight portion Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product;
4). with above-mentioned steps 1), 2) and 3) the fine powder mix homogeneously;
5). again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 3-9 hour with pure water 500-1500 weight portion, with slow fire boiling 0.5-1.5 hour, the reuse big fire decocted 20-60 minute, filter and remove residue, concentrate, put into above-mentioned steps 4) the medicated powder mixing, add conventional adjuvant and make tablet, granule, pill, capsule.
7, preparation method according to claim 6 is characterized in that this method is following steps:
1). Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder;
2). Gekko Swinhonis with 1 weight portion rice fry to sallow, grind into fine powder;
3). Mylabris head, foot, wing are removed, put into the oven dry of 1 weight portion Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product;
4). with above-mentioned steps 1), 2) and 3) the fine powder mix homogeneously;
5). again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 6 hours with pure water 1000 weight portions, with slow fire boiling 1 hour, the reuse big fire decocted 40 minutes, filter and remove residue, concentrate, put into above-mentioned steps 4) the medicated powder mixing, add conventional adjuvant and make tablet, granule, pill, capsule.
8, preparation method according to claim 6 is characterized in that this method is following steps:
1). Fructus Forsythiae, Radix Angelicae Sinensis, Radix Scutellariae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Notoginseng, Fructus Akebiae, Fructus Mume, Rhizoma Paridis, Scorpio, Bulbus Fritillariae Uninbracteatae, Herba Lobeliae Chinensis, Concha Arcae, Rhizoma Dioscoreae Bulbiferae, Semen Strychni, Scolopendra, Nidus Vespae, Agkistrodon, Rhizoma Chuanxiong, the Cortex Eucommiae, Herba Cistanches, Radix Fissistigmatis Glaucescentis, Rhizoma Pinelliae powder are broken into fine powder;
2). Gekko Swinhonis with 1 weight portion rice fry to sallow, grind into fine powder;
3). Mylabris head, foot, wing are removed, put into the oven dry of 1 weight portion Herba Gonostegiae Hirtae, Mylabris is removed, Herba Gonostegiae Hirtae grinds into fine powder and gets final product;
4). with above-mentioned steps 1), 2) and 3) the fine powder mix homogeneously;
5). again Flos Lonicerae, Semen Trichosanthis, Rhizoma Cimicifugae, the Radix Astragali, Herba Hedyotidis Diffusae, Fructus Crataegi, Bombyx Batryticatus, Poria, Radix Saposhnikoviae, Thallus Laminariae (Thallus Eckloniae) were soaked 6 hours with pure water 1000 weight portions, with slow fire boiling 1 hour, the reuse big fire decocted 40 minutes, filter and remove residue, be concentrated into the 230-670 weight portion, add the Mel of 130-390 and the dextrin of 180-540, put into above-mentioned steps 4 again) medicated powder mixing pill, oven dry, polishing are promptly.
9, pharmaceutical composition according to claim 5 is characterized in that said composition adds any dosage form that conventional adjuvant is made clinical acceptance, as tablet, capsule, a material agent, pill, emplastrum, ointment or spray.
10, the application of pharmaceutical composition according to claim 5 in preparation treatment esophageal carcinoma, gastric cancer, hepatocarcinoma, pulmonary carcinoma, uterus carcinoma, rectal cancer, breast carcinoma, cancer of pancreas, carcinoma of gastric cardia or leukemia medicament.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101954062A (en) * | 2010-09-29 | 2011-01-26 | 安政权 | Medicament for treating chronic pharyngitis |
| CN102100836A (en) * | 2011-01-24 | 2011-06-22 | 四川国康药业有限公司 | Medicinal composition for treating tumors, preparation method thereof and application thereof |
| CN101543616B (en) * | 2009-04-21 | 2012-07-04 | 闫树清 | Traditional Chinese medicine composition for preventing and treating tumor and its preparation method |
| CN102836405A (en) * | 2012-08-28 | 2012-12-26 | 刘国良 | Medicament for treating encephaloma |
| CN102961588A (en) * | 2012-12-17 | 2013-03-13 | 都匀市基佑生物科技有限公司 | Chinese herbal medicine decoction for treating rectal cancer |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102204992B (en) * | 2011-05-26 | 2015-05-06 | 张定国 | External application medicament for treating tumor |
-
2006
- 2006-03-31 CN CNB2006100664582A patent/CN100467045C/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543616B (en) * | 2009-04-21 | 2012-07-04 | 闫树清 | Traditional Chinese medicine composition for preventing and treating tumor and its preparation method |
| CN101954062A (en) * | 2010-09-29 | 2011-01-26 | 安政权 | Medicament for treating chronic pharyngitis |
| CN101954062B (en) * | 2010-09-29 | 2012-05-30 | 安政权 | Medicament for treating chronic pharyngitis |
| CN102100836A (en) * | 2011-01-24 | 2011-06-22 | 四川国康药业有限公司 | Medicinal composition for treating tumors, preparation method thereof and application thereof |
| CN102100836B (en) * | 2011-01-24 | 2012-07-04 | 四川国康药业有限公司 | Medicinal composition for treating tumors, preparation method thereof and application thereof |
| CN102836405A (en) * | 2012-08-28 | 2012-12-26 | 刘国良 | Medicament for treating encephaloma |
| CN102836405B (en) * | 2012-08-28 | 2014-09-10 | 刘国良 | Medicament for treating encephaloma |
| CN102961588A (en) * | 2012-12-17 | 2013-03-13 | 都匀市基佑生物科技有限公司 | Chinese herbal medicine decoction for treating rectal cancer |
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|---|---|
| CN100467045C (en) | 2009-03-11 |
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