CN1268348C - Antineoplastic combination of medication - Google Patents
Antineoplastic combination of medication Download PDFInfo
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- CN1268348C CN1268348C CNB2004100580130A CN200410058013A CN1268348C CN 1268348 C CN1268348 C CN 1268348C CN B2004100580130 A CNB2004100580130 A CN B2004100580130A CN 200410058013 A CN200410058013 A CN 200410058013A CN 1268348 C CN1268348 C CN 1268348C
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Abstract
The present invention relates to an anti-neoplastic medicine combination. The present invention is characterized in that the combination is mainly composed of pangolin, bezoar bovis, common prism tuber, rhizoma zedoariae, apricot kernel, raw sal ammoniac, smoked plum, Chicken's Gizzard-membrane, dragon blood, vietnamese sophora root, borax, akebia stem, radix et rhizoma rhei from sichuan of China, immature bitter orange, peach seed, rice, black bean, frankincense, myrrh, mung bean, catechu, cuttle, eaglewood, rhizoma corydalis, aucklandia root, cinnabar, pumice, magnolia bark, white mustard seed and aspongopus raw material medicines. The medicine composition of the present invention has the functions of clearing heat and removing toxicity, softening and resolving hard mass and resisting tumors, has notable therapeutic effects on lymphadenitis, scrofula, lymph tumor, nasopharyngeal cancer, rectum cancer, esophagus cancer, etc., and has no adverse reaction.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of antitumor medicine composition.
Background technology
Now, tumor treatment is still based on traditional operation, radiotherapy, three kinds of mode treatments of chemotherapy.Yet malignant tumor is early stage, often lacks specific symptom, after diagnosing middles and advanced stage that belong to more, often lost the surgical engine meeting, because the whole body situation is poor, also hard to bear strong radiotherapy, the chemotherapy etc. of being subjected to, or because chemotherapy repeatedly, tumor cell produces drug resistance, and conventional chemotherapy difficulty again proves effective.It is long-pending that motherland's medical science thinks that cancer belongs to disease, how because of the pent-up of feelings will, and the diet internal injury, positive QI-insufficiency, evil malicious internal resistance, stagnation of QI-blood, internal organs are deficient to be waited due to the imbalance of YIN and YANG, and Chinese medicine has become one of main treatment means.Seek determined curative effect, the PTS of safety non-toxic is current tumor research focus, is also looked forward to by numerous tumor patients.
Technology contents
The object of the present invention is to provide a kind of antitumor medicine composition.
The present invention is achieved through the following technical solutions: choose crude drug
Squama Manis 600-1800 weight portion Pulvis Fumi Carbonisatus 600-1800 weight portion
Rhizoma sparganic 600-1800 weight portion Rhizoma Curcumae 600-1800 weight portion
Semen Armeniacae Amarum 750-2250 weight portion is given birth to Sal Ammoniacus 450-1350 weight portion
Fructus Mume 450-1350 weight portion Endothelium Corneum Gigeriae Galli 600-1800 weight portion
Sanguis Draxonis 150-450 weight portion Radix Sophorae Tonkinensis 450-1350 weight portion
Borax 450-1350 weight portion Caulis Akebiae 400-1350 weight portion
The 450-1350 of Radix Et Rhizoma Rhei weight portion Fructus Aurantii Immaturus 450-1350 weight portion
Semen Persicae 450-1350 weight portion Semen Eutyales 450-1350 weight portion
Semen sojae atricolor 300-900 weight portion Olibanum 300-900 weight portion
Myrrha 300-900 weight portion Semen phaseoli radiati 300-900 weight portion
Catechu 300-900 weight portion Os Sepiae 300-900 weight portion
Lignum Aquilariae Resinatum 300-900 weight portion Rhizoma Corydalis 300-900 weight portion
Radix Aucklandiae 300-900 weight portion Cinnabaris 300-900 weight portion
Pumex 150-450 weight portion Cortex Magnoliae Officinalis 150-450 weight portion
Semen Sinapis Albae 150-450 weight portion Aspongopus 150-450 weight portion
The optimum ratio of the present composition is:
Squama Manis 1200 weight portion Pulvis Fumi Carbonisatuss 1200 weight portion rhizoma sparganic 1200 weight portions
Rhizoma Curcumae 1200 weight portion Semen Armeniacae Amarums 1500 weight portions are given birth to Sal Ammoniacus 900 weight portions
Fructus Mume 900 weight portion Endothelium Corneum Gigeriae Galli 1200 weight portion Sanguis Draxonis 300 weight portions
Radix Sophorae Tonkinensis 900 weight portion Boraxs 900 weight portion Caulis Akebiaes 900 weight portions
Radix Et Rhizoma Rhei's 900 weight portion Fructus Aurantii Immaturuss, 900 weight portion Semen Persicaes, 900 weight portions
Semen Eutyales 900 weight portion Semen sojae atricolors 600 weight portion Olibanums 600 weight portions
Myrrha 600 weight portion Semen phaseoli radiatis 600 weight portion catechu 600 weight portions
Os Sepiae 600 weight portion Lignum Aquilariae Resinatum 600 weight portion Rhizoma Corydalis 600 weight portions
The Radix Aucklandiae 600 weight portion Cinnabaris 600 weight portion Pumexes 300 weight portions
Cortex Magnoliae Officinalis 300 weight portion Semen Sinapis Albaes 300 weight portion Aspongopuss 300 weight portions
Pharmaceutical composition of the present invention adds acceptable accessories and makes clinical acceptable forms, as pill, tablet, oral liquid, capsule, granule etc.
Pharmaceutical composition of the present invention has heat-clearing and toxic substances removing, hard masses softening and resolving, and antitumor, to treatment lymphadenitis, lymphoid tuberculosis, lymph tumor, nasopharyngeal carcinoma, rectal cancer, many places tumor effects such as esophageal carcinoma are remarkable, have no adverse reaction.
Following experimental example is used to further specify the present invention.
1, physical data
The present invention was from July 8th, 2003--on May 9th, 2004, with the present invention's " the nuclear ball very should disappear " treatment lymphadenitis, lymphoid tuberculosis, lymph tumor, nasopharyngeal carcinoma, tumor patients such as rectal cancer, esophageal carcinoma 60 examples (patient all punctures, biopsy, the CT diagnosis), women's 25 examples, male's 35 examples.
2, diagnostic criteria
According to facing art and pathological diagnosis standard in the kinds of tumor diagnosis and treatment standard, all the other malignant tumor all confirm through image and pathological examination.
3, include standard in
Meet above-mentioned diagnostic criteria, without excision (except the postoperative recurrence person), or radiotherapy, chemotherapy special treatment person, include this group in and observe the case alternative.
4, exclusion standard
(1) severe cardiac hepatic and kidney function obstacle, gastrointestinal tract blocks or borer;
(2) score of KPS behavior state evaluation criteria estimates to be less than life cycle 2 months persons below 50 minutes.
5, Therapeutic Method
Medicine of the present invention is formed: Squama Manis 1200g, Pulvis Fumi Carbonisatus 1200g, rhizoma sparganic 1200g, Rhizoma Curcumae 1200g, Semen Armeniacae Amarum 1500g, give birth to Sal Ammoniacus 900g, Fructus Mume 900g, Endothelium Corneum Gigeriae Galli 1200g, Sanguis Draxonis 300g, Radix Sophorae Tonkinensis 900g, Borax 900g, Caulis Akebiae 900g, the 900g of Radix Et Rhizoma Rhei, Fructus Aurantii Immaturus 900g, Semen Persicae 900g, Semen Eutyales 900g, Semen sojae atricolor 600g, Olibanum 600g, Myrrha 600g, Semen phaseoli radiati 600g, catechu 600g, Os Sepiae 600g, Lignum Aquilariae Resinatum 600g, Rhizoma Corydalis 600g, Radix Aucklandiae 600g, Cinnabaris 600g, Pumex 300g, Cortex Magnoliae Officinalis 300g, Semen Sinapis Albae 300g, Aspongopus 300g.
Preparation technology: with said medicine routinely technology grind to the powder, make honeyed pill, the heavy 5g of every ball, every day 2-3 time, each 2-3 ball, taking medicine after meal, taboo tea, bean product, maror.30 days is a course of treatment, checks after 3 courses of treatment.
6, therapeutic outcome
Lymphadenitis, lymphoid tuberculosis, lymph tumor, nasopharyngeal carcinoma, rectal cancer, tumors such as esophageal carcinoma, 58 examples of fully recovering, the complete obiteration of enclosed mass symptom, 1 example is invalid, dead 1 example, the back individual patient reflection enclosed mass of taking medicine expands painful, and symptom disappears fast.Effective percentage reaches more than 96%.
Clinical effectiveness is observed and is shown: the present invention's " the nuclear ball very should disappear " treatment lymphadenitis, and lymphoid tuberculosis, lymph tumor, nasopharyngeal carcinoma, rectal cancer, many places tumor efficiencies such as esophageal carcinoma are not found untoward reaction certainly, can use multiple carcinoma patient yet.
7, model case
Case is the little unit of Pan 1., the man, and Han nationality, 48 years old, six groups in Pan Wan village, Xiangyang District Zhu market town, the patient is in excuse pain on May 26th, 2003, right cervical region enclosed mass March, outpatient service CT prompting: right side pharyngeal recess biopsy prompting " non-keratinization poor differentiated carcinoma ".The upper right neck of health check-up can touch 2 * 2cm enclosed mass, matter is hard, smooth, semifixed.Be diagnosed as nasopharyngeal carcinoma, lymph tumor.The patient comes me to go to a doctor by clinic on March 12nd, 2004, and the patient goes to a doctor with headache, lumbago, extremity edema, pharyngeal discomfort, cervical region enclosed mass; Make a definite diagnosis the same once more.Take the present invention " the nuclear ball very should disappear " treat.March 12 2004 first course of treatment (30 days)--April 12 3 times on the oral 1st, 1 time 2 ball, patient's headache, lumbago, edema disappear 1/3, and enclosed mass is softening; Second the 13 days-Mays 13 April course of treatment livery with the same, lumbago, headache, edema disappear, enclosed mass disappears 2/3; The 3rd May 14 course of treatment--June 24 took the same, and the symptom complete obiteration is followed up a case by regular visits to normal.
Case is Hu Zhiwei 2., the man, Han nationality, 26 years old, 15 groups in little all villages, town, peaceful shop, city, Fancheng City, Xiangfan City, patient main suit: on January 22nd, 2003, right cervical region enclosed mass one month, health check-up: right cervical region can touch 3 * 2cm size enclosed mass, movable (+) body temperature 36.8, through the colored puncture of Xiangfan City hospital of factory, the exfoliative cyte analysis, report is diagnosed as: lymphoid tuberculosis (appreciation type).Go to a doctor at this clinic on February 28th, 2004, be diagnosed as lymphoid tuberculosis once more, take the present invention's " the nuclear ball very should disappear " and carry out edge treatment--30 days courses of treatment.First February 28 course of treatment--the March 28,3 times on the oral 1st, patient's reflection, preceding 10 days some pain of enclosed mass, later enclosed mass is softening to disappear 1/3; Second March 29 course of treatment--oral the same April 29, the painless disappearance 3/4 of enclosed mass; The 3rd May 29 course of treatment--June 29, July 6, the complete obiteration of check symptom.
Following embodiment is used to further specify the present invention:
Embodiment 1
The white 1200g rhizoma sparganic 1200g Rhizoma Curcumae 1200g of Squama Manis 1200g grass
Semen Armeniacae Amarum 1500g gives birth to Sal Ammoniacus 900g Fructus Mume 900g Endothelium Corneum Gigeriae Galli 1200g
Sanguis Draxonis 300g Radix Sophorae Tonkinensis 900g Borax 900g Caulis Akebiae 900g
The 900g of Radix Et Rhizoma Rhei Fructus Aurantii Immaturus 900g Semen Persicae 900g Semen Eutyales 900g
Semen sojae atricolor 600g Olibanum 600g Myrrha 600g Semen phaseoli radiati 600g
Catechu 600g Os Sepiae 600g Lignum Aquilariae Resinatum 600g Rhizoma Corydalis 600g
Radix Aucklandiae 600g Cinnabaris 600g Pumex 300g Cortex Magnoliae Officinalis 300g
Semen Sinapis Albae 300g Aspongopus 300g
Said medicine technology routinely grinds to the powder, and makes honeyed pill, the heavy 5g of every ball, every day 2-3 time, each 2-3 ball.
Embodiment 2
Squama Manis 800g Pulvis Fumi Carbonisatus 1600g rhizoma sparganic 800g Rhizoma Curcumae 1600g
Semen Armeniacae Amarum 750g gives birth to Sal Ammoniacus 1350g Fructus Mume 1350g Endothelium Corneum Gigeriae Galli 600g
Sanguis Draxonis 150g Radix Sophorae Tonkinensis 1150g Borax 550g Caulis Akebiae 1250g
The 1150g of Radix Et Rhizoma Rhei Fructus Aurantii Immaturus 650g Semen Persicae 1150g Semen Eutyales 700g
Semen sojae atricolor 400g Olibanum 800g Myrrha 500g Semen phaseoli radiati 700g
Catechu 800g Os Sepiae 400g Lignum Aquilariae Resinatum 300g Rhizoma Corydalis 900g
Radix Aucklandiae 900g Cinnabaris 300g Pumex 200g Cortex Magnoliae Officinalis 400g
Semen Sinapis Albae 400g Aspongopus 200g
Said medicine technology is routinely made granule.
Embodiment 3
Squama Manis 1600g Pulvis Fumi Carbonisatus 800g rhizoma sparganic 1600g Rhizoma Curcumae 800g
Semen Armeniacae Amarum 2000g gives birth to Sal Ammoniacus 600g Fructus Mume 1250g Endothelium Corneum Gigeriae Galli 700g
Sanguis Draxonis 400g Radix Sophorae Tonkinensis 500g Borax 1200g Caulis Akebiae 550g
The 600g of Radix Et Rhizoma Rhei Fructus Aurantii Immaturus 1200g Semen Persicae 600g Semen Eutyales 1200g
Semen sojae atricolor 800g Olibanum 400g Myrrha 700g Semen phaseoli radiati 500g
Catechu 400g Os Sepiae 800g Lignum Aquilariae Resinatum 800g Rhizoma Corydalis 400g
Radix Aucklandiae 800g Cinnabaris 400g Pumex 400g Cortex Magnoliae Officinalis 200g
Semen Sinapis Albae 200g Aspongopus 400g
Said medicine technology is routinely made tablet.
Claims (5)
1, a kind of antitumor medicine composition is characterized in that said composition mainly made by following crude drug:
Squama Manis 600-1800 weight portion Pulvis Fumi Carbonisatus 600-1800 weight portion
Rhizoma sparganic 600-1800 weight portion Rhizoma Curcumae 600-1800 weight portion
Semen Armeniacae Amarum 750-2250 weight portion is given birth to Sal Ammoniacus 450-1350 weight portion
Fructus Mume 450-1350 weight portion Endothelium Corneum Gigeriae Galli 600-1800 weight portion
Sanguis Draxonis 150-450 weight portion Radix Sophorae Tonkinensis 450-1350 weight portion
Borax 450-1350 weight portion Caulis Akebiae 400-1350 weight portion
The 450-1350 of Radix Et Rhizoma Rhei weight portion Fructus Aurantii Immaturus 450-1350 weight portion
Semen Persicae 450-1350 weight portion Semen Eutyales 450-1350 weight portion
Semen sojae atricolor 300-900 weight portion Olibanum 300-900 weight portion
Myrrha 300-900 weight portion Semen phaseoli radiati 300-900 weight portion
Catechu 300-900 weight portion Os Sepiae 300-900 weight portion
Lignum Aquilariae Resinatum 300-900 weight portion Rhizoma Corydalis 300-900 weight portion
Radix Aucklandiae 300-900 weight portion Cinnabaris 300-900 weight portion
Pumex 150-450 weight portion Cortex Magnoliae Officinalis 150-450 weight portion
Semen Sinapis Albae 150-450 weight portion Aspongopus 150-450 weight portion.
2, pharmaceutical composition according to claim 1, its feature said composition is mainly made by following crude drug:
Squama Manis 1200 weight portion Pulvis Fumi Carbonisatuss 1200 weight portion rhizoma sparganic 1200 weight portions
Rhizoma Curcumae 1200 weight portion Semen Armeniacae Amarums 1500 weight portions are given birth to Sal Ammoniacus 900 weight portions
Fructus Mume 900 weight portion Endothelium Corneum Gigeriae Galli 1200 weight portion Sanguis Draxonis 300 weight portions
Radix Sophorae Tonkinensis 900 weight portion Boraxs 900 weight portion Caulis Akebiaes 900 weight portions
Radix Et Rhizoma Rhei's 900 weight portion Fructus Aurantii Immaturuss, 900 weight portion Semen Persicaes, 900 weight portions
Semen Eutyales 900 weight portion Semen sojae atricolors 600 weight portion Olibanums 600 weight portions
Myrrha 600 weight portion Semen phaseoli radiatis 600 weight portion catechu 600 weight portions
Os Sepiae 600 weight portion Lignum Aquilariae Resinatum 600 weight portion Rhizoma Corydalis 600 weight portions
The Radix Aucklandiae 600 weight portion Cinnabaris 600 weight portion Pumexes 300 weight portions
Cortex Magnoliae Officinalis 300 weight portion Semen Sinapis Albaes 300 weight portion Aspongopuss 300 weight portions.
3, pharmaceutical composition according to claim 1, its feature said composition is mainly made by following crude drug:
Squama Manis 800 weight portion Pulvis Fumi Carbonisatuss 1600 weight portion rhizoma sparganic 800 weight portions
Rhizoma Curcumae 1600 weight portion Semen Armeniacae Amarums 750 weight portions are given birth to Sal Ammoniacus 1350 weight portions
Fructus Mume 1350 weight portion Endothelium Corneum Gigeriae Galli 600 weight portion Sanguis Draxonis 150 weight portions
Radix Sophorae Tonkinensis 1150 weight portion Boraxs 550 weight portion Caulis Akebiaes 1250 weight portions
Radix Et Rhizoma Rhei's 1150 weight portion Fructus Aurantii Immaturuss, 650 weight portion Semen Persicaes, 1150 weight portions
Semen Eutyales 700 weight portion Semen sojae atricolors 400 weight portion Olibanums 800 weight portions
Myrrha 500 weight portion Semen phaseoli radiatis 700 weight portion catechu 800 weight portions
Os Sepiae 400 weight portion Lignum Aquilariae Resinatum 300 weight portion Rhizoma Corydalis 900 weight portions
The Radix Aucklandiae 900 weight portion Cinnabaris 300 weight portion Pumexes 200 weight portions
Cortex Magnoliae Officinalis 400 weight portion Semen Sinapis Albaes 400 weight portion Aspongopuss 200 weight portions.
4, pharmaceutical composition according to claim 1, its feature said composition is mainly made by following crude drug:
Squama Manis 1600 weight portion Pulvis Fumi Carbonisatuss 800 weight portion rhizoma sparganic 1600 weight portions
Rhizoma Curcumae 800 weight portion Semen Armeniacae Amarums 2000 weight portions are given birth to Sal Ammoniacus 600 weight portions
Fructus Mume 1250 weight portion Endothelium Corneum Gigeriae Galli 700 weight portion Sanguis Draxonis 400 weight portions
Radix Sophorae Tonkinensis 500 weight portion Boraxs 1200 weight portion Caulis Akebiaes 550 weight portions
Radix Et Rhizoma Rhei's 600 weight portion Fructus Aurantii Immaturuss, 1200 weight portion Semen Persicaes, 600 weight portions
Semen Eutyales 1200 weight portion Semen sojae atricolors 800 weight portion Olibanums 400 weight portions
Myrrha 700 weight portion Semen phaseoli radiatis 500 weight portion catechu 400 weight portions
Os Sepiae 800 weight portion Lignum Aquilariae Resinatum 800 weight portion Rhizoma Corydalis 400 weight portions
The Radix Aucklandiae 800 weight portion Cinnabaris 400 weight portion Pumexes 400 weight portions
Cortex Magnoliae Officinalis 200 weight portion Semen Sinapis Albaes 200 weight portion Aspongopuss 400 weight portions.
5,, it is characterized in that said composition adds pharmaceutically receptible adjuvant and makes clinical receptible dosage form, any as in pill, tablet, oral liquid, capsule, the granule according to claim 1,2,3 or 4 described Chinese medicine compositions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100580130A CN1268348C (en) | 2004-08-06 | 2004-08-06 | Antineoplastic combination of medication |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100580130A CN1268348C (en) | 2004-08-06 | 2004-08-06 | Antineoplastic combination of medication |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1626225A CN1626225A (en) | 2005-06-15 |
| CN1268348C true CN1268348C (en) | 2006-08-09 |
Family
ID=34764262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100580130A Expired - Fee Related CN1268348C (en) | 2004-08-06 | 2004-08-06 | Antineoplastic combination of medication |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1268348C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055214A (en) * | 2013-01-05 | 2013-04-24 | 马长林 | Traditional Chinese medicine for treating nasopharynx cancer by utilizing lepidogrammitis intermedia |
| KR101746639B1 (en) | 2010-07-02 | 2017-06-14 | (주)아모레퍼시픽 | Composition with skin lightening and moisturizing effects containing bee venom extracts |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391006B (en) * | 2008-11-11 | 2011-10-05 | 李全国 | Medicine composition for treating tumor and preparation method thereof |
-
2004
- 2004-08-06 CN CNB2004100580130A patent/CN1268348C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101746639B1 (en) | 2010-07-02 | 2017-06-14 | (주)아모레퍼시픽 | Composition with skin lightening and moisturizing effects containing bee venom extracts |
| CN103055214A (en) * | 2013-01-05 | 2013-04-24 | 马长林 | Traditional Chinese medicine for treating nasopharynx cancer by utilizing lepidogrammitis intermedia |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1626225A (en) | 2005-06-15 |
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Granted publication date: 20060809 |