CN1233354C - Chinese medicine preparation for treating carcinoma of esophagus - Google Patents
Chinese medicine preparation for treating carcinoma of esophagus Download PDFInfo
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- CN1233354C CN1233354C CN 02135136 CN02135136A CN1233354C CN 1233354 C CN1233354 C CN 1233354C CN 02135136 CN02135136 CN 02135136 CN 02135136 A CN02135136 A CN 02135136A CN 1233354 C CN1233354 C CN 1233354C
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Abstract
The present invention provides a Chinese medicine preparation for treating esophageal cancer, which is mainly prepared from the following crude drugs: 5 to 10 portions of aucklandia root, 10 to 15 portions of tuckahoe, 0.2 to 0.4 portion of natural bezoar, 5 to 10 portions of unibract fritillary bulb, 3 to 9 portions of amomun fruit, 5 to 15 portions of red sage root, 10 to 15 portions of lucid asparagus, 10 to 15 portions of largehead atractylodes rhizome, 3 to 10 portions of licorice root, 15 to 20 portions of peppermint, 10 to 15 portions of dendrobe, 10 to 30 portions of polygonatum, 13 to 30 portions of rehmannia root, 10 to 15 portions of radix adenophorae, 1.5 to 3 portions of camphol, 10 to 30 portions of barbed skullcap herb, 3 to 6 portions of notoginseng, 3 to 10 portions of curcuma, 0.3 to 0.5 portions of moschus, 15 to 60 portions of long-noded pit viper, 3 to 9 portions of safflower, 5 to 10 portions of peach seed, 3 to 10 portions of ginseng, 15 to 20 portions of astragalus root, 1 to 3 portions of pilose antler and 10 to 30 portions of prepared rhizome of rehmannia. In addition, the effective treatment rate of the Chinese medicine preparation is 100%, the obvious effective rate is more than 90 %, effects usually act in 3 to 7 days after oral administration, the average life time of most patients with cancer can be prolonged for more than 3 to 8 years when the preparation is continuously taken, and patients that survive for more than 10 years are very common. Therefore, compared with other Chinese medicines and western medicines for treating esophageal carcinoma in the prior art, the Chinese medicine preparation has the characteristics of high therapeutic effect, no toxic or side effect, etc., and has good use value for popularization.
Description
1, technical field
The present invention relates to a kind of preparation method of Chinese patent medicine, specifically a kind of Chinese medicine preparation for the treatment of the esophageal carcinoma.
2, technical background
Esophageal carcinoma, carcinoma of gastric cardia are the higher malignant cancer of a kind of sickness rate, seriously harm humans is healthy, the patient is when suffering huge mental suffering, also suffered insufferable misery, at present, World Health Organization (WHO) still, does not also have bigger progress at present esophageal carcinoma, the carcinoma of gastric cardia key subjects as medical research.
The esophageal carcinoma clinical manifestation can have saliva increasing in early days, and sense is stagnated in foreign body in esophagus sense, feed, along with typical dysphagia appears in the development of the state of an illness, the general food of elder generation, then semi-fluid flows at last that juice or saliva are neither can be swallowed, and causes water and electrolyte disturbance etc. to cancerate and jeopardizes patient's life.When finding dysphagia, during the state of an illness of Most patients has developed into, late period.Though operation, radiotherapy plus chemotherapy can prolong patient's life, huge economic cost makes the patient be difficult to accept, and toxic and side effects is bigger.Along with the breakthrough of oncomolecularbiology research, tumor therapeutics has also increased abundant content more in recent years.At present, many knowledgeable people begin sight is turned to the research and development of natural antitumor medicine, the history that Chinese medicine had combat the disease in several thousand, aspect oncotherapy, accumulated suitable rich experience, modern Chinese medicine studies show that, many Chinese herbal medicine are being killed tumor cell, the human body immunity improving function, alleviation is put, there is huge potentiality to be exploited the chemical therapy toxic side effect aspect, through the excelsior unremitting effort of several generations,, add continuous research and the development of having the courage to bring forth new ideas with the practical experience of traditional Chinese medical science secret prescription handed down in the family from generation to generation with for the theory of medicine combination, formed the specific short of treatment esophageal carcinoma, enriched the clinical treatment experience of Chinese medicine the esophageal carcinoma.
3, goal of the invention
The purpose of this invention is to provide a kind of therapeutic effect good, have no side effect, the Chinese medicine preparation of through port is taken medicine and application compress develop simultaneously the treatment esophageal carcinoma.
The selected side that respectively distinguishes the flavor of Chinese herbal medicine separates as follows in the Chinese medicine preparation of the treatment esophageal carcinoma of the present invention:
The Radix Aucklandiae: acrid in the mouth, hardship, warm in nature, go into lung, liver, spleen channel.
Effect: promoting the circulation of QI to relieve pain, warming middle-JIAO and mouse-anti cancer.
Clinical practice: this product is usually used in the liver helmet stagnation of QI, and the pent-up mouth is of a specified duration, and the digestive system tumor of formation is as food Bo cancer, gastric cancer etc.
Poria: sweet in the mouth, light, property is flat, goes into the heart, spleen, kidney channel.
Effect: the sharp key of eliminating dampness by diuresis, the albefaction sputum, the spleen invigorating invigorating middle warmer, centering is calmed the nerves.
Clinical practice: this product can be used for resisting, suppressing the development of cancer, kills the growth of anticancer, is applicable to various cancers such as the esophageal carcinoma, gastric cancer, intestinal cancer.It is insufficiency of the spleen and performance such as edema and ascites to occur particularly suitable to belong to the traditional Chinese medical science to the ill.
Natural Calculus Bovis: bitter in the mouth, sweet, cool in nature, go into the heart, Liver Channel.
Effect: clear away heart-fire and reduce phlegm, function of gallbladder promoting, relieving convulsion anticancer, heat-clearing and toxic substances removing, reduce phlegm, have one's ideas straightened out, control that ulcer is rotted, skin sore.
Clinical practice: be widely used in and control intracranial tumour and cerebral tumor transfer, the esophageal carcinoma, hepatocarcinoma, breast carcinoma, leukemia, lymphoma etc.Hyperactivity of toxic heat, heart spirit confused by phlegm, impatency passages through which vital energy circulates person is particularly suitable.To carbuncle ulcer, lean pain also has the effect of reducing swelling and alleviating pain.
Bulbus Fritillariae Cirrhosae: sweet in the mouth, hardship, be slightly cold, go into the heart, lung meridian.
Effect: removing heat-phlegm, nourishing the lung to arrest cough, the eliminating stagnation spasmolytic, dissipating depression of QI is removed red-hot effect.
Clinical practice: this product can be treated pulmonary carcinoma, and mediastinum tumor, lung-heat are stopped up knot, mental disorder, phlegm-fire hand over resistance person outstanding it.
Fructus Amomi: acrid in the mouth, little hardship, warm in nature, go into spleen shoulder warp.
Effect: removing dampness is amusing, relieving QI stagnancy in the stomach.
Clinical practice: this product is mainly used in digestive system tumor and the esophageal carcinoma, gastric cancer etc. are the most suitable with retention of damp leading to blockage of QI etc.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature is gone into the conscience lung, Liver Channel.
Effect: invigorate blood circulation, removing heat from blood, stasis-dispelling and pain-killing, centering is calmed the nerves, and is anticancer.
Clinical practice: be widely used in gastric cancer and disturb and be suitable for qi depression to blood stasis, the patient who accumulates in the pyretic toxicity.
Radix Asparagi: sweet in the mouth, hardship, cold in nature, go into lung, kidney channel.
Effect: YIN nourishing, moisturize, lung heat clearing, pathogenic fire reducing, anticancer.
Clinical practice: this product is anticancer drug supporting healthy energy commonly used, and all various tumors syndrome of endogenous heat due to yin deficiency thes occur, and the person all can use.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature, go into spleen, stomach warp.
Effect: the spleen reinforcing stomach reinforcing, dampness and in.
Clinical practice: the wood product are mainly used in digestive tract tumor.Belong to the weakness of the spleen and stomach person with card and be advisable, the effect of leukocyte increasing in addition of wood product is used to put, leukopenia caused by cancer chemotherapy disease.
Radix Glycyrrhizae: sweet in the mouth, property is flat, goes into spleen, stomach, the heart, lung meridian.
Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain.
Clinical practice: be used for deficiency of QI in middle-JIAO, the various middle and advanced stage tumors of deficiency of both QI and blood are used for swollen lame compound recipe and can alleviate or lower some drugs high strong property and toxicity thereof more.
Herba Menthae: acrid in the mouth, cool in nature, go into liver, lung meridian.
Effect: dispelling wind and heat pathogens, the refresh oneself, throat, wind and heat eliminating, the strongly fragrant breast for the treatment of the liver is coerced, stagnant heat is withered disease.
Clinical practice: the headache due on wind heat, attacking, conjunctival congestion or laryngopharynx swelling and pain.Can cooperate other medicines treatment brain tumor, laryngeal neoplasm, jaw hole cancer, lymphatic cancer, skin carcinoma etc.
Herba Dendrobii: sweet in the mouth, light, little salty, cold in nature, go into stomach, lung, kidney channel.
Effect: nourishing the stomach to promote the production of body fluid, nourishing kidney heat extraction, lung moistening kidney tonifying.
Clinical practice: this product is usually used in illness such as esophageal carcinoma, carcinoma of gastric cardia, gastric cancer, mediastinum tumor, and is the most suitable with deficiency of YIN Tianjin the wounded.
Rhizoma Polygonati Odorati: sweet in the mouth, property is flat, goes into lung, the stomach warp.
Effect: nourishing YIN and moistening the lung, reinforcing stomach reg fluid, anticancer.
Clinical practice: wood product leak that profit is sweet flat, and kind the moon of supporting the lung stomach is used for the treatment of respiratory system, digestive system tumor more, burn brightly with hyperactivity of toxic heat, pathogenic heat with esophageal carcinoma, gastric cancer etc., consume impairment of YIN liquid person and are advisable.
The Radix Rehmanniae: sweet in the mouth, hardship, cold nature.
Effect: the effect of YIN nourishing and the production of body fluid promoting, clearing away heat and cooling blood is arranged, be commonly used to treat warm, dysphoria with smothery sensation is thirsty, dry tongue Tianjin is few, and cloudy Tianjin consumption is hindered disease, and the labor disease of deficiency of YIN hectic fever due to YIN-deficiency dysphoria with smothery sensation, also is usually used in the caused hemorrhage that makes preparations for sowing of heat in blood in addition.
Clinical practice: fever caused by exogenous pathogenic factors, heat is gone into nutrient blood, and heat is impairment of YIN very, body fluid deficiency constipation person, that uses then increases the liquid loosening bowel to relieve constipation.
Radix Adenophorae (Radix Glehniae): sweet in the mouth, cold nature is gone into lung shoulder warp.
Effect: nourishing YIN and clearing away lung-heat, beneficial helmet promotes the production of body fluid, and is anticancer.
Clinical practice: this product can be supported the moon of lung, stomach, thus clinical many in order to treatment pulmonary carcinoma, gastric cancer, be used for lung, deficiency of stomach-YIN person more.
Borneolum Syntheticum: acrid in the mouth, hardship, QI exhaustion fragrance, cool in nature, go into the heart, lung meridian.
Effect: cure mainly in the expectorant heat and close, ulcer sores, the open hole powder fire, refreshment makes eye bright, the effect of reducing swelling and alleviating pain.
Clinical practice: can be used for the cancer pain that skin carcinoma, the esophageal carcinoma etc. cause, definite curative effect is also arranged.
Herba Scutellariae Barbatae: acrid in the mouth, little hardship, cool in nature, go into liver, stomach, large intestine channel.
Effect: the energy heat-clearing and toxic substances removing, the malignant boil carbuncle is treated, and inducing diuresis to remove edema has anticancer effect.
Clinical practice: this product is anticancer medicine commonly used, can be used for various cancers, is used for digestive tract tumor especially more, and the person is advisable to see the damp-heat accumulation with card, also is widely used in the hemorrhage disease of tumor companion, can play hemostasis and does not stay the effect of the stasis of blood.
Radix Notoginseng: sweet in the mouth, little hardship, warm in nature, go into liver, stomach, the heart, lung ten large intestine channels.
Effect: hemostasis is invigorated blood circulation, stasis-dispelling and pain-killing, detumescence, the effect of analgesic therapy.
Clinical practice: this product can be widely used in various cancers, especially to the cancer pain lump due to the knot in the blood stasis, hemorrhagely waits disease that curative effect is preferably arranged.
Radix Curcumae: acrid in the mouth, hardship, cool in nature, go into the heart, lung, Liver Channel.
Effect: promoting QI circulation for relieving depression, drop blood removing blood stasis with potent drugs, anticancer analgetic.
Clinical practice: how not busy in deficiency of QI in middle-JIAO, the various middle and advanced stage tumors of deficiency of both QI and blood are used for tumor ascites and can alleviate or lower some drugs high strong property and toxicity thereof.
Moschus: acrid in the mouth, warm in nature, fragrance is the key medicine of having one's ideas straightened out especially.Be apt to ward off foul bad odor, and can calm the frightened.Be usually used in convulsions, coma, syncope due to accumulation of phlegm and in dirty bad odor sudden faint etc. close disease.The antidotal effect is also fine in addition.And invigorate blood circulation, the meridian dredging and analgesic effect, traumatic injury, the blood stasis that the carbuncle of its treatment surgery commonly used is covered infections and traumatology disease such as have a pain.No matter for oral administration, external, curative effect is all fine.
Be applied to: dominance of heat in the interior, the hot key of expectorant such as close at disease.Clinically can be used for the treatment that helmet cancer, elbow cancer, intracranial tumour or swollen addiction vertigo move.
Hedyotidis Diffusae: bitter in the mouth, sweet, cold in nature, go into the heart, liver, spleen channel.
Effect: heat-clearing and toxic substances removing damp eliminating detumescence, promoting blood circulation and stopping pain is controlled the cancerous protuberance malignant tumor.
Clinical practice: this product is widely used in the various tumors of treatment, is used for controlling digestive system tumor especially more, the esophageal carcinoma, gastric cancer, and stagnant person is the most suitable with the hyperactivity of toxic heat phlegm-damp stasis of blood.
Flos Carthami: acrid in the mouth, warm in nature, go into the heart, liver, spleen channel.
Effect: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, anticancer.The effect of moisturizing laxation is arranged, be applicable to the constipation of large intestine deficiency of body fluid, the effect of blood stasis removing and clots absorbing is arranged again.
Clinical practice: be used for swelling and pain due to blood stasis, qi stagnation hemagglutination, dry, the body fluid deficiency constipation person of deficiency of YIN blood more, can control QI rising in reverse order in addition and breath with cough, chest and diaphragm feeling of fullness person.This product is widely used in the esophageal carcinoma, the multiple malignant tumor of gastric cancer, blood stasis congelation, and lump causes that obvious pain person is particularly suitable.
Semen Persicae: bitter in the mouth, sweet, property is flat, goes into liver, spleen channel.
Effect: the effect of moisturizing laxation is arranged, be applicable to the constipation of large intestine deficiency of body fluid, the effect of blood stasis removing and clots absorbing is arranged again.
Clinical practice: be used for swelling and pain due to blood stasis, qi stagnation hemagglutination, dry, the body fluid deficiency constipation person of deficiency of YIN blood more, can control QI rising in reverse order in addition and breath with cough, chest and diaphragm feeling of fullness person.
Radix Ginseng: sweet in the mouth, tepor is gone into lung, spleen channel.
Effect: strongly invigorating primordial QI, lung benefiting spleen reinforcing, promote the production of body fluid and nourish blood, calm the nerves Fructus Alpiniae Oxyphyllae, anticancer.
Clinical practice: Radix Ginseng tonification vigour, promote the production of body fluid and nourish blood, can strengthening body, strengthen the immune function of health, suppress tumor growth, the control leukopenia.If be used in combination in radiotherapy or the chemotherapy, can alleviate the caused side effect of radiotherapy or chemotherapy.
The Radix Astragali: sweet in the mouth, warm in nature, go into lung, spleen channel.
Effect: tonifying Qi and lifting yang, consolidating superficial resistance is received antiperspirant, holder skin ulcer granulation promoting, the effect of inducing diuresis to remove edema.
Clinical practice: can be used for treating the deficiency of vital energy disease of various tumors, reduce the toxic and side effects that causes because of chemotherapy.
Cornu Cervi Pantotrichum: sweet in the mouth, salty, warm in nature, go into kidney.
Effect: the effect that mainly contains invigorating kidney-YANG, benefiting essence-blood, QI invigorating.Can control the deficiency and coldness skin infection and wear and do not close up for a long time after bursting, take a tonic or nourishing food to build up one's health the effect that expelling the toxic substance from the body with tonic has promoting tissue regeneration and wound healing with its.
Clinical practice: can treat kidney yang deficiency, kidney qi is lost empty, and the vital essence deficiency waits the kidney invigorating and essence nourishing, strong muscles and bones, sets upright anti-heresy.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature is gone into liver, lung, kidney channel.
Effect: the YIN nourishing of enriching blood, life essence-filling, marrow-benefitting, anticancer.
Clinical practice: be widely used in multiple cancer such as esophageal carcinoma and be particularly useful for the hepatic and renal YIN deficiency, evilly contain the cancer patient who declines down, use this product can the enhancing body resistance, improve the various cancer of late stage of immune function, asthenia of qi and blood declines, and YIN-fluid being insufficient person all can use.The blocking-up canceration had significant curative effect.
Carapax Et Plastrum Testudinis: salty in the mouth, sweet, property is flat, goes into liver, kidney channel.
Effect: YIN nourishing is anticancer, the kidney invigorating YANG hyperactivity suppressing, strong kidney consolidating channel for hemostasis, dissipating blood stasis for subsidence of swelling, blood stasis removing blood.
Clinical practice: the cancer patient is belonged to the hyperactivity of YANG due to deficiency of YIN, and the person is more suitable.Wherein the esophageal carcinoma, hepatocarcinoma, renal carcinoma, pulmonary carcinoma, breast carcinoma, nasopharyngeal carcinoma etc. all there is therapeutical effect preferably.
The Chinese medicine preparation of the treatment esophageal carcinoma of the present invention is made up of oral medicine and application compress, and oral medicine is to be made by following Chinese medicine raw materials by weight proportion:
Radix Aucklandiae 5-10 part; Poria 10-15 part; natural Calculus Bovis 0.2-0.4 part; Bulbus Fritillariae Cirrhosae 5-10 part; Fructus Amomi 3-9 part; Radix Salviae Miltiorrhizae 5-15 part; Radix Asparagi 10-15 part; Rhizoma Atractylodis Macrocephalae 10-15 part; Radix Glycyrrhizae 3-10 part; Herba Menthae 15-20 part; Herba Dendrobii 10-15 part; Rhizoma Polygonati Odorati 10-30 part; Radix Rehmanniae 13-30 part; Radix Adenophorae (Radix Glehniae) 10-15 part; Borneolum Syntheticum 15-3 part; Herba Scutellariae Barbatae 10-30 part; Radix Notoginseng 3-6 part; Radix Curcumae 3-10 part; Moschus 0.3-0.5 part; Hedyotidis Diffusae 15-60 part; Flos Carthami 3-9 part; Semen Persicae 5-10 part; Radix Ginseng 3-10 part; Radix Astragali 15-20 part; Cornu Cervi Pantotrichum 1-3 part; Radix Rehmanniae Preparata 10-30 part.
In the Chinese medicine preparation of the present invention, respectively the distinguish the flavor of preferred weight proportioning of raw material of Chinese medicine of oral medicine is:
Radix Aucklandiae 7-8 part; Poria 12-13 part; natural Calculus Bovis 0.2-0.3 part; Bulbus Fritillariae Cirrhosae 7-9 part; Fructus Amomi 5-7 part; Radix Salviae Miltiorrhizae 8-12 part; Radix Asparagi 11-13 part; Rhizoma Atractylodis Macrocephalae 11-13 part; Radix Glycyrrhizae 6-9 part; natural Calculus Bovis 0.3-0.4 part; Herba Menthae 16-18 part; Herba Dendrobii 11-14 part; Rhizoma Polygonati Odorati 15-20 part; Radix Rehmanniae 18-25 part; Radix Adenophorae (Radix Glehniae) 11-13 part; Borneolum Syntheticum: 1.5-2 part; Herba Scutellariae Barbatae 15-25 part; Radix Notoginseng 4-5 part; Radix Curcumae 6-8 part; Moschus 0.4-0.5 part; Hedyotidis Diffusae 20-40 part; Flos Carthami 5-8 part; Semen Persicae 6-9 part; Radix Ginseng 5-8 part; Radix Astragali 16-19 part; Cornu Cervi Pantotrichum 2-3 part; Radix Rehmanniae Preparata 15-26 part.
In preparation of the present invention, respectively the distinguish the flavor of optimum weight proportioning of raw material of Chinese medicine of oral medicine is:
8 parts of the Radix Aucklandiae, 13 parts in Poria, 0.3 part of natural Calculus Bovis, 7 parts of Bulbus Fritillariae Cirrhosaes, 5 parts of Fructus Amomis, 12 parts of Radix Salviae Miltiorrhizaes, 13 parts of Radix Asparagi, 11 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts in Radix Glycyrrhizae, 0.3 part of natural Calculus Bovis, 17 parts of Herba Menthaes, 13 parts of Herba Dendrobiis, 16 parts of Rhizoma Polygonati Odorati, 20 parts in the Radix Rehmanniae, 13 parts of Radix Adenophorae (Radix Glehniae), Borneolum Syntheticum: 1.5 parts, 21 parts of Herba Scutellariae Barbataes, 4 parts of Radix Notoginseng, 7 parts of Radix Curcumaes, 0.5 part in Moschus, 30 parts of Hedyotidis Diffusaes, 6 parts on Flos Carthami, 8 parts in Semen Persicae, 7 parts of Radix Ginsengs, 17 parts of the Radixs Astragali, 3 parts in Cornu Cervi Pantotrichum, 20 parts in Radix Rehmanniae Preparata.
In preparation of the present invention, application compress are to be made by following Chinese medicine raw materials by weight proportion:
Moschus 0.3-0.5 part, Carapax Et Plastrum Testudinis 15-30 part, Radix Notoginseng 3-6 part, Hedyotidis Diffusae 15-60 part, Herba Scutellariae Barbatae 10-30 part, Flos Carthami 3-9 part, Semen Persicae 5-10 part, Radix Glycyrrhizae 3-10 part, Radix Curcumae 4-9 part, Radix Salviae Miltiorrhizae 5-15 part, Herba Menthae 15-20 part.
In preparation of the present invention, respectively the distinguish the flavor of preferred weight proportioning of raw material of Chinese medicine of application compress is:
Moschus 0.3-0.4 part, Carapax Et Plastrum Testudinis 18-25 part, Radix Notoginseng 4-5 part, Hedyotidis Diffusae 30-40 part, Herba Scutellariae Barbatae 15-25 part, Flos Carthami 5-7 part, Semen Persicae 6-8 part, Radix Glycyrrhizae 6-8 part, Radix Curcumae 6-7 part, Radix Salviae Miltiorrhizae 8-12 part, Herba Menthae 17-18 part.
In preparation of the present invention, respectively the distinguish the flavor of optimum weight proportioning of raw material of Chinese medicine of application compress is:
0.3 part in Moschus, 20 parts of Carapax Et Plastrum Testudiniss, 5 parts of Radix Notoginseng, 35 parts of Hedyotidis Diffusaes, 20 parts of Herba Scutellariae Barbataes, 7 parts on Flos Carthami, 6 parts in Semen Persicae, 6 parts in Radix Glycyrrhizae, 7 parts of Radix Curcumaes, 10 parts of Radix Salviae Miltiorrhizaes, 17 parts of Herba Menthaes.
Oral medicine in the Chinese medicine preparation of the present invention is said powder, capsule, tablet or an oral liquid on the pharmaceutics, and liniment is a said unguentum on the pharmaceutics.
The preparation method of oral medicine is in the Chinese medicine preparation of the present invention: take by weighing the herbal raw material of respectively distinguishing the flavor of in proportion and dry respectively and be crushed to 120 purpose fine powders, be mixed in proportion then under 100 ℃ of-110 ℃ of temperature and sterilized 10-30 minute, be processed into powder, capsule, tablet or oral liquid by traditional pharmaceutical technology.
The preparation of liniment is in proportion each flavor raw material of Chinese medicine to be added burned in Oleum sesami, and cool after-filtration waste adds Plumbum preparatium by 1: 1 weight ratio again and continues to endure when becoming pearl in splashing into water to ending, and separates by equal portions, and every part 50 restrains, spreads out on cream cloth and be finished product.
4, embodiment
Prescription one
Take by weighing the oral liquid raw material of Chinese medicine of respectively distinguishing the flavor of in proportion:
8 parts of the Radix Aucklandiae, 13 parts in Poria, 0.3 part of natural Calculus Bovis, 7 parts of Bulbus Fritillariae Cirrhosaes, 5 parts of Fructus Amomis, 12 parts of Radix Salviae Miltiorrhizaes, 13 parts of Radix Asparagi, 11 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts in Radix Glycyrrhizae, 0.3 part of natural Calculus Bovis, 17 parts of Herba Menthaes, 13 parts of Herba Dendrobiis, 16 parts of Rhizoma Polygonati Odorati, 20 parts in the Radix Rehmanniae, 13 parts of Radix Adenophorae (Radix Glehniae), 1.5 parts of Borneolum Syntheticums, 21 parts of Herba Scutellariae Barbataes, 4 parts of Radix Notoginseng, 7 parts of Radix Curcumaes, 0.5 part in Moschus, 30 parts of Hedyotidis Diffusaes, 6 parts on Flos Carthami, 8 parts in Semen Persicae, 7 parts of Radix Ginsengs, 17 parts of the Radixs Astragali, 3 parts in Cornu Cervi Pantotrichum, 20 parts in Radix Rehmanniae Preparata.
Take by weighing the raw material of Chinese medicine of respectively distinguishing the flavor of by formula proportion:
0.3 part in Moschus, 20 parts of Carapax Et Plastrum Testudiniss, 5 parts of Radix Notoginseng, 35 parts of Hedyotidis Diffusaes, 20 parts of Herba Scutellariae Barbataes, 7 parts on Flos Carthami, 6 parts in Semen Persicae, 6 parts in Radix Glycyrrhizae, 7 parts of Radix Curcumaes, 10 parts of Radix Salviae Miltiorrhizaes, 17 parts of Herba Menthaes.
The preparation method of oral medicine is: take by weighing the raw material of Chinese medicine of respectively distinguishing the flavor of in proportion and dry respectively and be crushed to 120 purpose fine powders, be mixed in proportion then under 100 ℃ of-110 ℃ of temperature and sterilized 10-30 minute, be processed into powder, capsule, tablet or oral liquid by traditional pharmaceutical technology.
The preparation of liniment is in proportion each flavor raw material of Chinese medicine to be added burned in Oleum sesami, and cool after-filtration waste adds Plumbum preparatium by 1: 1 weight ratio again and continues to endure when becoming pearl in splashing into water to ending, and separates by equal portions, and every part 50 restrains, spreads out on cream cloth and be finished product.
Prescription two
Take by weighing the oral medicine raw material of Chinese medicine of respectively distinguishing the flavor of in proportion:
5 parts of the Radix Aucklandiae, 11 parts in Poria, 0.2 part of natural Calculus Bovis, 8 parts of Bulbus Fritillariae Cirrhosaes, 6 parts of Fructus Amomis, 13 parts of Radix Salviae Miltiorrhizaes, 11 parts of Radix Asparagi, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 7 parts in Radix Glycyrrhizae, 0.4 part of natural Calculus Bovis, 19 parts of Herba Menthaes, 13 parts of Herba Dendrobiis, 15 parts of Rhizoma Polygonati Odorati, 24 parts in the Radix Rehmanniae, 14 parts of Radix Adenophorae (Radix Glehniae), 1.6 parts of Borneolum Syntheticums, 23 parts of Herba Scutellariae Barbataes, 5 parts of Radix Notoginseng, 6 parts of Radix Curcumaes, 0.4 part in Moschus, 32 parts of Hedyotidis Diffusaes, 7 parts on Flos Carthami, 6 parts in Semen Persicae, 5 parts of Radix Ginsengs, 16 parts of the Radixs Astragali, 4 parts in Cornu Cervi Pantotrichum, 22 parts in Radix Rehmanniae Preparata.
Take by weighing the raw material of Chinese medicine of respectively distinguishing the flavor of by formula proportion:
0.4 part in Moschus, 18 parts of Carapax Et Plastrum Testudiniss, 6 parts of Radix Notoginseng, 30 parts of Hedyotidis Diffusaes, 24 parts of Herba Scutellariae Barbataes, 6 parts on Flos Carthami, 5 parts in Semen Persicae, 5 parts in Radix Glycyrrhizae, 8 parts of Radix Curcumaes, 13 parts of Radix Salviae Miltiorrhizaes, 18 parts of Herba Menthaes.
Prescription three
Take by weighing the oral liquid raw material of Chinese medicine of respectively distinguishing the flavor of in proportion:
5 parts of the Radix Aucklandiae, 11 parts in Poria, 0.2 part of natural Calculus Bovis, 8 parts of Bulbus Fritillariae Cirrhosaes, 6 parts of Fructus Amomis, 13 parts of Radix Salviae Miltiorrhizaes, 11 parts of Radix Asparagi, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 7 parts in Radix Glycyrrhizae, 0.4 part of natural Calculus Bovis, 19 parts of Herba Menthaes, 13 parts of Herba Dendrobiis, 15 parts of Rhizoma Polygonati Odorati, 24 parts in the Radix Rehmanniae, 14 parts of Radix Adenophorae (Radix Glehniae), 1.6 parts of Borneolum Syntheticums, 23 parts of Herba Scutellariae Barbataes, 5 parts of Radix Notoginseng, 6 parts of Radix Curcumaes, 0.4 part in Moschus, 32 parts of Hedyotidis Diffusaes, 7 parts on Flos Carthami, 6 parts in Semen Persicae, 5 parts of Radix Ginsengs, 16 parts of the Radixs Astragali, 4 parts in Cornu Cervi Pantotrichum, 22 parts in Radix Rehmanniae Preparata.
Take by weighing the raw material of Chinese medicine of respectively distinguishing the flavor of by formula proportion:
0.4 part in Moschus, 18 parts of Carapax Et Plastrum Testudiniss, 6 parts of Radix Notoginseng, 30 parts of Hedyotidis Diffusaes, 24 parts of Herba Scutellariae Barbataes, 6 parts on Flos Carthami, 5 parts in Semen Persicae, 5 parts in Radix Glycyrrhizae, 8 parts of Radix Curcumaes, 13 parts of Radix Salviae Miltiorrhizaes, 18 parts of Herba Menthaes.
The preparation of oral medicine and application compress is identical with prescription one.
The clinical practice of treatment esophageal carcinoma Chinese medicine preparation of the present invention:
Application compress are attached to focus epidermis place, each 10 grams of oral medicine, every day 3 times.
Model case:
Case one
Li Yulian, woman, 75 years old, people from Tai, Shandong.Before 3 years, be " esophagus stage casing cancer " about 8-9cm through hospital diagnosis, the chemotherapy of being in hospital has spent several ten thousand yuan, does not have good curative effect, and life has been lost confidence; Take of the present invention oral will with application compress after over 2 years, clap the x mating plate, controlled canceration, at present, appetite is normal, takes care of oneself.
Case two
Yu Zhaolan, woman, 83 years old.People from village of Donga County, the Shandong Qun Dynasty.Be diagnosed as esophagus hypomere cancer by the People's Hospital, Tianjin in 1984,6-8cm, use the treatment of oral medicine of the present invention and application compress after, health is good over 16 years.
Case three
Diao Mingxi, man, 80 years old.Donga, Shandong Province county Cao collects the village people.Before 4 years, suffer from stage casing cancer on the esophagus through hospital diagnosis, have little effect behind the hospitalization, use after the Drug therapy of the present invention, the state of an illness is controlled fully, and at present, transference cure, appetite are normal.
Case four
Yu Yueting, woman, 80 years old.People from Yantai City, Shandong Province is diagnosed as hypomere cancer in the trouble esophagus through tumour hospital, adopts after the treatment of oral medicine of the present invention and application compress, and the state of an illness is controlled, respond well.
Case five
Pompeii China, woman, 82 years old.People from Weifang City, Shandong.Suffer from hypomere cancer 6-8cm in the esophagus through hospital diagnosis, controlled symptom after adopting the treatment of oral medicine of the present invention and application compress, it is normal to live over 2 years.
The about Therapeutic Method of Chinese medicine preparation of the present invention by for oral administration and external application proves 300 many cases cancer patients' treatment, the double effects that this Chinese medicine preparation has the human body immunity improving function and the cancer that disappears presses down, makes focus atrophy apoptosis at the propagation by improving the body's immunological function control cancer cell.Show that by statistics the treatment effective percentage of this Chinese medicine preparation is 100%, obvious effective rate is taken medicine usually and can be taken effect in 3-7 days more than 90%, can both be more than the life-saving 3-8 after most cancer patients adhere to taking medicine, and survival is very general above the patient in 10 years.Therefore, the medicine of the integrative therapy esophageal carcinoma of this Chinese medicine preparation and prior art is compared, and characteristics such as have the curative effect height, have no side effect have good value for applications.
Claims (5)
1. Chinese medicine preparation for the treatment of the esophageal carcinoma, make by oral medicine and application compress: it is characterized in that oral medicine is to be made by following Chinese medicine raw materials by weight proportion:
Radix Aucklandiae 5-10 part, Poria 10-15 part, natural Calculus Bovis 0.2-0.4 part, Bulbus Fritillariae Cirrhosae 5-10 part, Fructus Amomi 3-9 part, Radix Salviae Miltiorrhizae 5-15 part, Radix Asparagi 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Radix Glycyrrhizae 3-10 part, Herba Menthae 15-20 part, Herba Dendrobii 10-15 part, Rhizoma Polygonati Odorati 10-30 part, Radix Rehmanniae 13-30 part, Radix Adenophorae (Radix Glehniae) 10-15 part, Borneolum Syntheticum 1.5-3 part, Herba Scutellariae Barbatae 10-30 part, Radix Notoginseng 3-6 part, Radix Curcumae 3-10 part, Moschus 0.3-0.5 part, Hedyotidis Diffusae 15-60 part, Flos Carthami 3-9 part, Semen Persicae 5-10 part, Radix Ginseng 3-10 part, Radix Astragali 15-20 part, Cornu Cervi Pantotrichum 1-3 part, Radix Rehmanniae Preparata 10-30 part;
Application compress are to be made by following Chinese medicine raw materials by weight proportion:
Moschus 0.3-0.5 part, Carapax Et Plastrum Testudinis 15-30 part, Radix Notoginseng 3-6 part, Hedyotidis Diffusae 15-60 part, Herba Scutellariae Barbatae 10-30 part, Flos Carthami 3-9 part, Semen Persicae 5-10 part, Radix Glycyrrhizae 3-10 part, Radix Curcumae 4-9 part, Radix Salviae Miltiorrhizae 5-15 part, Herba Menthae 15-20 part.
2. Chinese medicine preparation according to claim 1 is characterized in that respectively the distinguish the flavor of weight proportion of raw material of Chinese medicine of oral medicine is:
Radix Aucklandiae 7-8 part, Poria 12-13 part, natural Calculus Bovis 0.2-0.3 part, Bulbus Fritillariae Cirrhosae 7-9 part, Fructus Amomi 5-7 part, Radix Salviae Miltiorrhizae 8-12 part, Radix Asparagi 11-13 part, Rhizoma Atractylodis Macrocephalae 11-13 part, Radix Glycyrrhizae 6-9 part, natural Calculus Bovis 0.3-0.4 part, Herba Menthae 16-18 part, Herba Dendrobii 11-14 part, Rhizoma Polygonati Odorati 15-20 part, Radix Rehmanniae 18-25 part, Radix Adenophorae (Radix Glehniae) 11-13 part, Borneolum Syntheticum 1.5-2 part, Herba Scutellariae Barbatae 15-25 part, Radix Notoginseng 4-5 part, Radix Curcumae 6-8 part, Moschus 0.4-0.5 part, Hedyotidis Diffusae 20-40 part, Flos Carthami 5-8 part, Semen Persicae 6-9 part, Radix Ginseng 5-8 part, Radix Astragali 16-19 part, Cornu Cervi Pantotrichum 2-3 part, Radix Rehmanniae Preparata 15-26 part;
The weight proportion of raw material of Chinese medicine of respectively distinguishing the flavor of in the application compress is:
Moschus 0.3-0.4 part, Carapax Et Plastrum Testudinis 18-25 part, Radix Notoginseng 4-5 part, Hedyotidis Diffusae 30-40 part, Herba Scutellariae Barbatae 15-25 part, Flos Carthami 5-7 part, Semen Persicae 6-8 part, Radix Glycyrrhizae 6-8 part, Radix Curcumae 6-7 part, Radix Salviae Miltiorrhizae 8-12 part, Herba Menthae 17-18 part.
3. Chinese medicine preparation according to claim 1 is characterized in that respectively the distinguish the flavor of weight proportion of raw material of Chinese medicine of oral medicine is:
8 parts of the Radix Aucklandiae, 13 parts in Poria, 0.3 part of natural Calculus Bovis, 7 parts of Bulbus Fritillariae Cirrhosaes, 5 parts of Fructus Amomis, 12 parts of Radix Salviae Miltiorrhizaes, 13 parts of Radix Asparagi, 11 parts of the Rhizoma Atractylodis Macrocephalaes, 6 parts in Radix Glycyrrhizae, 0.3 part of natural Calculus Bovis, 17 parts of Herba Menthaes, 13 parts of Herba Dendrobiis, 16 parts of Rhizoma Polygonati Odorati, 20 parts in the Radix Rehmanniae, 13 parts of Radix Adenophorae (Radix Glehniae), 1.5 parts of Borneolum Syntheticums, 21 parts of Herba Scutellariae Barbataes, 4 parts of Radix Notoginseng, 7 parts of Radix Curcumaes, 0.5 part in Moschus, 30 parts of Hedyotidis Diffusaes, 6 parts on Flos Carthami, 8 parts in Semen Persicae, 7 parts of Radix Ginsengs, 17 parts of the Radixs Astragali, 3 parts in Cornu Cervi Pantotrichum, 20 parts in Radix Rehmanniae Preparata;
The weight proportion of raw material of Chinese medicine of respectively distinguishing the flavor of in the application compress is:
0.3 part in Moschus, 20 parts of Carapax Et Plastrum Testudiniss, 5 parts of Radix Notoginseng, 35 parts of Hedyotidis Diffusaes, 20 parts of Herba Scutellariae Barbataes, 7 parts on Flos Carthami, 6 parts in Semen Persicae, 6 parts in Radix Glycyrrhizae, 7 parts of Radix Curcumaes, 10 parts of Radix Salviae Miltiorrhizaes, 17 parts of Herba Menthaes.
4. according to the described Chinese medicine preparation of claim 1-3, it is characterized in that oral medicine is said powder, tablet or an oral liquid on the pharmaceutics, application compress are said unguentum on the pharmaceutics.
5. Chinese medicine preparation according to claim 1, the preparation process that it is characterized in that oral medicine is: take by weighing the herbal raw material of respectively distinguishing the flavor of in proportion and dry respectively and be crushed to 120 purpose fine powders, be mixed in proportion then under 100 ℃ of-110 ℃ of temperature and sterilized 10-30 minute, be processed into powder by traditional pharmaceutical technology, capsule, tablet or oral liquid, the preparation process of liniment is in proportion each flavor crude drug to be added burned in the Oleum sesami, cool after-filtration waste, adding Plumbum preparatium by 1: 1 weight ratio again continues to endure when becoming pearl in splashing into water for ending, separate by equal portions, every part 50 gram spreads out on cream cloth and is finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02135136 CN1233354C (en) | 2002-06-24 | 2002-06-24 | Chinese medicine preparation for treating carcinoma of esophagus |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 02135136 CN1233354C (en) | 2002-06-24 | 2002-06-24 | Chinese medicine preparation for treating carcinoma of esophagus |
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| CN1465387A CN1465387A (en) | 2004-01-07 |
| CN1233354C true CN1233354C (en) | 2005-12-28 |
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| CN 02135136 Expired - Fee Related CN1233354C (en) | 2002-06-24 | 2002-06-24 | Chinese medicine preparation for treating carcinoma of esophagus |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101352549B (en) * | 2008-09-08 | 2011-01-26 | 长沙慈航药物研究所有限公司 | Anticancer Chinese patent medicine with functions of anti-tumor metastasis and induction of tumor cell differentiation |
| CN102940842B (en) * | 2012-10-01 | 2014-05-07 | 喻可安 | Anti-esophageal cancer drug |
| CN103028077B (en) * | 2012-12-24 | 2014-03-19 | 秦旭东 | Traditional Chinese medicine preparation for treating tumors |
| CN104826018B (en) * | 2015-05-13 | 2019-01-08 | 李双阳 | Double lotus perfume (or spice) electuaries and preparation method thereof |
| CN104800585A (en) * | 2015-05-14 | 2015-07-29 | 奉化科创科技服务有限公司 | Traditional Chinese medicine for treating esophageal cancer |
| CN105596519A (en) * | 2016-01-07 | 2016-05-25 | 南阳医学高等专科学校第一附属医院 | Traditional Chinese medicine composition for treating achalsaia caused by liver depression and qi stagnation and preparation method thereof |
| CN109663117A (en) * | 2019-01-31 | 2019-04-23 | 杨全胜 | A kind of drug for treating cancer |
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