CN105596519A - Traditional Chinese medicine composition for treating achalsaia caused by liver depression and qi stagnation and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating achalsaia caused by liver depression and qi stagnation and preparation method thereof Download PDF

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CN105596519A
CN105596519A CN201610004833.4A CN201610004833A CN105596519A CN 105596519 A CN105596519 A CN 105596519A CN 201610004833 A CN201610004833 A CN 201610004833A CN 105596519 A CN105596519 A CN 105596519A
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何明
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First Affiliated Hospital of Nanyang Medical College
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Abstract

The invention discloses a traditional Chinese medicine composition for treating achalsaia caused by liver depression and qi stagnation and a preparation method thereof. The traditional Chinese medicine composition is prepared from an orally-taken medicine composition and a medicine composition for external use. The orally-taken medicine composition is prepared from, by weight, 5-8 parts of Coridius chinensis, 10-15 parts of herba cistanche, 20-25 parts of Tuber Fleece flower stems, 18-25 parts of all-grass or roots of Fourangular Crotalaria, 12-18 parts of Hedyotis diffusa, 15-20 parts of Valeriana officinalis L., 8-12 parts of fructus aurantii, 6-10 parts of Radix Salviae Miltiorrhizae, 6-12 parts of dragon bone and 10-15 parts of cicada shells. The medicine composition for external use is prepared from, by weight, 25-35 parts of Faeces Trogopterpri, 20-30 parts of red peony roots, 20-30 parts of Tetradium ruticarpum, 10-20 parts of common vladimiria roots and 5-10 parts of Fagopyrum tataricum. The composition is good in treatment effect, high in effective rate and free of toxic and side effects on human bodies.

Description

Chinese medicine composition for the treatment of stagnation of QI due to depression of the liver maga-esophagus and preparation method thereof
Technical field
The present invention relates to medical GI Medicine Chinese medicine composition technical field, particularly Chinese medicine composition of a kind of GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus and preparation method thereof.
Background technology
Maga-esophagus belongs to esophageal motility obstacle disease, refer to swallow rear EB without wriggling, the cardiac sphincter bad a kind of disease of relaxing, claim again cardiospasm. Cardinal symptom has dysphagia, anti-stream vomiting, chest discomfort or pain. This disease is a kind of rare disease (estimates every 100,000 in everybody only approximately 1 people), can betide any age, ganglion cell's quantity that its main pathology is changed into neuropile between esophageal wall reduces even disappearance, can involve whole Thorax esophgus, the most obvious with oesophagus middle and lower part, this disease treatment has the danger of the potential generation cancer of the esophagus not in time. Current methods for the treatment of mainly adopts treatment with western, PCI and operative treatment. Conventional medicine mainly contains calcium channel blocker, nitrate esters or anticholinergic agents, although can effectively reduce LES pressure can respite dysphagia, can not improve esophageal peristalsis; Physical expansion therapy in PCI, simple and safe operation, damage little, misery less, few intercurrent disease, cardio-pulmonary function be badly damaged and late pregnancy all applicable, conventional have air bag, water pocket and a various bougienage, but need to pass through repeated multiple times expansion, the complication such as the excessive postoperative easy generation perforation of pressure and reflux esophagitis, also can cause Esophageal Mucosa scarring, fibrillatable sometimes; It is slow that operative treatment recovers, and wound is large, Esophageal Mucosa may occur and break, the complication such as ceasma hernia and gastroesophageal reflux. Caused by hepatic stagnation qi stagnation maga-esophagus clinical symptoms are: swallow stalk and choke, eat and spue, chest diaphragm ruffian is vexed, meets anger more very, pink tongue, and tongue is thin, and pulse condition string is thin, and the state of an illness more recurs seriously, cures difficulty large.
Summary of the invention
The Chinese medicine composition of the treatment caused by hepatic stagnation qi stagnation maga-esophagus that the object of the present invention is to provide good, the efficient height of a kind of result for the treatment of, human body is had no side effect.
Another object of the present invention is to provide a kind of preparation method of Chinese medicine composition of this treatment caused by hepatic stagnation qi stagnation maga-esophagus.
For achieving the above object, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of stagnation of QI due to depression of the liver maga-esophagus, is made up of oral medicament composition and externally-applied medicinal composition, described oral medicament composition is made up of the raw material of following weight portion: 5~8 parts of aspongopus, 10~15 parts of saline cistanches, 20~25 parts of Polygonum multiflower knotweeds, 18~25 parts of tetragonal crotalaria herbs, 12~18 parts of HERBA HEDYOTIS DIFFUSAEs, 15~20 parts of valerians, 8~12 parts of Fructus Aurantiis, 6~10 parts of the reds sage root, 6~12 parts of keel, 10~15 parts of PERIOSTRACUM CICADAEs; Described externally-applied medicinal composition is made up of the raw material of following weight portion: 25~35 parts of excrementum pteropis, 20~30 parts of the radix paeoniae rubrathe, 20~30 parts of evodia rutaecarpas, 10~20 parts of the banksia rose, 5~10 parts of duck wheats.
Preferably, described oral medicament composition is made up of the raw material of following weight portion: 6 parts of aspongopus, 11 parts of saline cistanches, 21 parts of Polygonum multiflower knotweeds, 20 parts of tetragonal crotalaria herbs, 14 parts of HERBA HEDYOTIS DIFFUSAEs, 16 parts of valerians, 9 parts of Fructus Aurantiis, 7 parts of the reds sage root, 8 parts of keel, 11 parts of PERIOSTRACUM CICADAEs; Described externally-applied medicinal composition is made up of the raw material of following weight portion: 28 parts of excrementum pteropis, 22 parts of the radix paeoniae rubrathe, 22 parts of evodia rutaecarpas, 12 parts of the banksia rose, 6 parts of duck wheats.
The preparation method of the Chinese medicine composition of this treatment stagnation of QI due to depression of the liver maga-esophagus, it is characterized in that: the preparation method of described oral medicament composition comprises the following steps: get respectively each component raw material by described proportioning and pick up clean impurity elimination, all raw material stoving were pulverized 150~200 mesh sieves and were made powder, then mix by described proportioning, incapsulate or granulation or make tablet; The preparation method of described externally-applied medicinal composition comprises the following steps:
1) raw material of externally-applied medicinal composition are crushed to respectively to 80~100 orders;
2) excrementum pteropi, the radix paeoniae rubrathe, the distillation of evodia rutaecarpa steam method, obtain crystal A;
Get the dregs of a decoction mixing surplus stock after distillation, then toward the ethanol that adds 95% in clear cream, mix and blend, makes it contain alcohol amount and reaches 70%, leaves standstill alcohol precipitation; Get supernatant and reclaim ethanol, collect mixture B;
3) crystal A and mixture B are mixed, be concentrated into thick paste shape medicinal extract, medicinal extract is pressed on nonwoven, make herbal application.
Endo-medicine and external used medicine that the present invention treats GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus use jointly, wherein, and the instructions of taking of endo-medicine: every day 2~3 times, each 2~3, every 9~12g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 30~35g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether.
Below in conjunction with selected Chinese medicine and pharmacological property, its effect is described further.
Aspongopus, this product is the dry body of Pentatomidae Insects aspongopus AspongopuschinensisDallas. Salty, temperature. Return liver,spleen,kidney warp. Regulating qi-flowing for relieving pain is supporing yang in temperature. For stomach cold distending pain, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach, impotence due to deficiency of the kidney, soreness of waist and knee joint.
Saline cistanche, taste is sweet; Salty; Warm in nature, return kidney; Large intestine channel, kidney-replenishing; Benefiting essence-blood; Ease constipation road. Main decline of kidney-YANG; The impotence of asthenia of essence and blood; Seminal emission; Gonorrhoea; The frequent micturition heeltap; Pain in the back flaccidity of lower limbs; Tinnitus order flower; Menstruation is spread out the phase; Fertility; The dry constipation of intestines, the key medicine of nourshing kidney replenishing vital essence and blood, this tepor of gas, thinks hot person's mistake also according to legend. The bowl spares of sweet energy heat extraction, acid can enter liver, the nourshing kidney of salty energy, kidney liver is cloudy, and cloudy gas is grown, and the labor of the five internal organs heat is moved back certainly, fever and chills self-healing bitterly in penis. Kidney liver foot, essence and blood day contains, and essence and blood is contained how sub. Gynecological mass in abdomen, the disease appearing in blood system, blood exuberant then OK, capable abdominal mass disappears certainly. Bladder void, evil visitor, must mend that perverse trend is from loose, and pain in the back is from stopping. For a long time clothes are fertile strong and make light of one's life by commiting suicide, and the effect of kidney-nourishing liver replenishing vital essence and blood also, is controlled dysentery if say, sliding to lead stagnant meaning, this also can not say also. Warming middle energizer to promote qi, relieving diarrhea with astringents. For deficiency-cold in spleen and stomach, endless diarrhea, institute's abdominal distention and pain, the few vomiting of food.
Polygonum multiflower knotweed: sweet, micro-hardship, flat. The thoughts of returning home, Liver Channel. Mental-tranquilization, dispels the wind, dredging collateral. For insomnia, dreaminess, the deficiency of blood, numbness, arthralgia due to wind-dampness, the diseases such as rubella itch.
Tetragonal crotalaria herb: pungent, clinical in yellow subcutaneous ulcer, heat is drenched, micro-bitterness, cool temperature. Return stomach, large intestine, small intestinl channel. Clearing heat and detoxicating, dampness removing is treating stranguria, promoting qi circulation and relieving pain. Wing caryolytes stone, stomachache, the lump in the abdomen disease such as do not disappear.
HERBA HEDYOTIS DIFFUSAE: sweet, cold. The thoughts of returning home, liver, spleen, large intestine channel. Clearing heat and detoxicating, dampness removing. For dyspnea and cough due to lung-heat, abscess of throat, acute appendicitis, furuncle sore, venomous snake bite, heat is drenched puckery pain etc.
Valerian: acrid, bitter, warm. The thoughts of returning home, Liver Channel. Tranquilizing mind. For confused and worried, palpitation and insomnia, demented, arthralgia due to wind-dampness, dysmenorrhoea, through closing, the diseases such as traumatic injury.
Fructus Aurantii, property hardship, pungent, sour, warm, spleen benefiting and stimulating the appetite, adjusts the five internal organs, lower gas, preventing or arresting vomiting is contrary, dissolving phlegm. Control gastric disorder causing nausea, cholera is rushed down dysentery, helps digestion, broken crux Xuan addiction, and five types of dysphagia, except wind improving eyesight and lung qi oedema, sharp intestine and small intestine, skin is itched
The red sage root, bitter, is slightly cold, nontoxic. Stasis-dispelling and pain-killing, activating blood to promote menstruation, relieving restlessness clears away heart-fire. Warp. Promoting blood circulation for regulating menstruation, the cool blood carbuncle that disappears, calms the nerves. Ambition, institute's abdomen pain and knurl addiction for blood addiction are gathered, arthralgia due to wind-dampness, and sore carbuncle is swollen etc.
Keel, sweet-puckery flavor, property is flat, the thoughts of returning home, liver, ' kidney channel, function tranquillizing the mind by relieving convulsion, calming the liver, restrain astringent or styptic treatment for spontaneous sweating, for having no peace of mind, palpitation and insomnia, frightened carbuncle is demented, dizziness due to hyperactivity of liver-YANG, all diseases of slippage, wet sore pruigo, sore is burst and is not held back for a long time. Shennong's Herbal: " keel taste is sweet flat, main trusted subordinate, and ghost note, the old evil spirit of smart thing, coughs contraryly, rushes down dysentery purulence blood, and woman leaks down one, and children's's hot gas is shied carbuncle. " Compendium of Material Medica: " kidney-nourishing is relieving convulsion, draws tear cruel, hygroscopic gas, prolapse of the anus, regenerating tissue to heal wond. " modern pharmacology research shows: keel have anticonvulsant action, its anticonvulsant action and copper, manganese element content is relevant.
PERIOSTRACUM CICADAE, sweet, cold. Return liver, lung channel. Dispelling wind and heat from the body, promoting eruption is antipruritic, removing nebula for improving eyesight, breath wind stops convulsion. Containing a large amount of chitins. Sedation. Can reduce reflex response and striated muscle tensity, and nerve is had to blocking effect.
Excrementum pteropi, also, smell is all thick for liver channel of foot-Jueyin medicine, and the yin aspect of yin, therefore enter blood system. The main blood of liver, so medicine can be controlled blood disease, loose blood and blood and stop all pains. Zhi Jing Epilepsy, except malaria dysentery, long-pending the reducing phlegm that disappear, treats infantile malnutrition due to digestive disturbances or intestinalparasites desinsection, controls blood-arthralgia, all diseases of blood eye, all belongs to Liver Channel also. Shixiao San is not only controlled the pained blood pain of married woman, and all trusted subordinates of all men and women, old and young coerce rib hypogastric pain hernia, and tire vim and vigour in front postpartum are had a pain and metrorrhagia warp overflows, and all can yield result. Press again Li Zhong south cloud, excrementum pteropi is controlled metrorrhagia, and the non-medicine of only controlling blood is the agent of wind. Punching is appointed through void, is attacked ying blood by wind wound, thus metrorrhagia sudden and violent under, with schizonepeta, windproof control collapse justice with. It is abstruse so that ancients' knowledge and insight is realized by side, and this also one says, perseverance not and liver blood deficiency stagnant, the also meaning of spontaneous wind.
Evodia rutaecarpa, pungent; Bitter; Heat; Enter liver, stomach warp. Wen Zhong, pain relieving, regulates the flow of vital energy, and eliminating dampness tonifies the liver and kidney, restrains admittedly de-. Evodia rutaecarpa has preventing or arresting vomiting, antiulcer, and digestion promoting function, analgesic activity, antithrombotic forms, antibacterial, antiviral, hepatoprotective effect. The cloudy headache that is used for fainting, cold hernia abdomen pain, the disturbance of lower legs due to pathogenic cold and dampness, through row abdomen pain, gastral cavity tripe distending pain, vomiting acid regurgitation, Diarrhoea. Control aphtha outward, hypertension.
The radix paeoniae rubrathe, bitter, cold nature. For thermal man's ying blood, febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, through closing dysmenorrhoea, addiction lump in the abdomen stomachache, injury from falling down, the carbuncle sore that swells.
The banksia rose, nature and flavor: pungent taste is pungent; Bitter; Warm in nature. Promoting the circulation of qi, pain relieving, invigorating the spleen, helps digestion, promoting qi circulation and relieving pain; In tune, lead stagnant. Main born of the same parents coerce turgor foot; Abdominal distention; Tell and have loose bowels; Heavy after dysentery. For chest gastral cavity distending pain, rush down heavy after dysentery, dyspepsia does not disappear, do not feel like eating; Middle gas is not economized; Burst is deaf; Snake bite and insect sting; Toothache. The abdominal fullness and distention of the taste stagnation of the circulation of vital energy or pain, belch, n and V.
Duck wheat, hardship, flat. Have effect of regulating qi-flowing for relieving pain, invigorating spleen to remove dampness, duck wheat has the effect for the treatment of stomachache, indigestion, lumbocrural pain, traumatic injury.
The inventor has carried out a large amount of investigation, analysis and research are thought, along with social development and economic having more than needed, people's life, diet structure have a very large change. an outstanding feature is exactly the high-pressure of the unscrupulous and spirit of life. the unscrupulous main manifestations of life is night work's daily interest, and order is inverted, meals are thrown off restraint the sweet fertilizer of food, and rare vegetables are omnivorous. work again commonplace busy, spirit is for a long time in high-pressure state, rarely loosely rests and take nourishing food to build up one's health recuperate. unordered the unbalance of the system of digesting and assimilating that bring of life, excessive food consumption, heat are coldly fought mutually, cause nutrition to be received less, and two is just inaccessible, and the stasis of blood is long-pending grows wild. long-pendingization of stasis of blood poison, enters blood system, and hyperamization fat raises, and blood is slow, stagnant in internal organs, cause that each portion function is weak, and then void is lost plain body, stagnant in stomach, invest inwall, the congested passage of digesting and assimilating, causes stasis of blood day of year very, stagnant in space between skin and muscles, stop up Xuan Tongzhi road. long this visceral organ injury, function day declines, and void thanks to must. the anxiety of spirit, psychological constrains, the origin of disaster especially, the catharsis of liver mistake, inferior taste, the heart, kidney, the lungs of undermining, five-element Xiang Bo, imbalance of yin and yang, and lead thus, vicious circle, day falls into more. all this causes hematogenous blockage, liver is suffered from a deficiency of the kidney and loses, the dysfunction of the spleen in transport, qi-blood-body fluid deficiency, digestive system suffers damage, and cause while swallowing food and after conscious breastbone, have and obstruct the difficult lower sense of choking, or intermittent non-carrying out property dysphagia, the state of an illness can increase and decrease with emotional change, or with regurgitation of food and retrosternal pain. X ray barium meal examination oesophagus is expansion and prolongation and bending obviously, and without peristaltic wave, distal esophagus is symmetric form infundibular stenosis to pars cardiaca 1~3cm section, and mucosal pattern is normal, and stomach bottom is abnormal without other. gastrocopy oesophagus is obviously expanded. the visible esophageal lumen of distal esophagus in expansion is narrow ringwise, smooth mucosal, and under mucous membrane, nothing infiltrates, and gets rid of the diseases such as chorionitis, amyloidosis, tumour. the present invention, according to chinese tradition theory of medicine, takes stopgap measures and effects a permanent cure, and radicallys reform, fundamentally improve stagnation of QI due to depression of the liver, treatment cardia achalasia, according to the Clinical symptoms of oesophagus duty door achalasia, this disease should belong to the categories such as traditional Chinese medicine " card of choking ", " gastric disorder causing nausea ", " stomachache ". regulate liver dysfunction of spleen and stomach, the mechanism of qi retardance of dredging taste and then profit taste, regulate elevating function. raw material of the present invention all adopt dried raw material, saline cistanche of the present invention, tetragonal crotalaria herb expel flatulence and relieve chest stuffiness, promote the production of body fluid to quench thirst, for monarch drug in a prescription, keel, red sage root supplementing qi and nourishing yin, valerian, HERBA HEDYOTIS DIFFUSAE promotes the production of body fluid to quench thirst, for ministerial drug, PERIOSTRACUM CICADAE nourishing yin to moisten dryness, promote the production of body fluid to quench thirst, Fructus Aurantii clearing heat and promoting fluid, wide chest appetizing, the long-pending shell wide chest of regulating the flow of vital energy, Polygonum multiflower knotweed yin-nourishing, benefit stomach, promote the production of body fluid, silkworm chrysalis promotes the production of body fluid, quench the thirst, aspongopus is tonified the liver and kidney, wind-weed clearing heat-fire, nourshing Yin and drynsessmoistening prescription, all medicine compatibilities use above, play altogether clearing heat and nourishing yin, reinforcing stomach reg fluid, moisturize effect of purging intense heat, the particularly important is to take orally with external application and play good synergy, reach the object for the treatment of caused by hepatic stagnation qi stagnation maga-esophagus.
Detailed description of the invention
Embodiment 1:
A kind of Chinese medicine composition of GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus, be made up of oral medicament composition and externally-applied medicinal composition, described oral medicament composition is made up of the raw material of following weight portion: 5 parts of aspongopus, 10 parts of saline cistanches, 20 parts of Polygonum multiflower knotweeds, 18 parts of tetragonal crotalaria herbs, 12 parts of HERBA HEDYOTIS DIFFUSAEs, 15 parts of valerians, 8 parts of Fructus Aurantiis, 6 parts of the reds sage root, 6 parts of keel, 10 parts of PERIOSTRACUM CICADAEs; Described externally-applied medicinal composition is made up of the raw material of following weight portion: 25 parts of excrementum pteropis, 20 parts of the radix paeoniae rubrathe, 20 parts of evodia rutaecarpas, 10 parts of the banksia rose, 5 parts of duck wheats.
The preparation method of described oral medicament composition comprises the following steps: get respectively each component raw material by described proportioning and pick up clean impurity elimination; all raw material stoving were pulverized 150 mesh sieves and were made powder; then mix by described proportioning, incapsulate or granulation or make tablet.
The preparation method of described externally-applied medicinal composition comprises the following steps:
1) raw material of externally-applied medicinal composition are crushed to respectively to 80 orders;
2) excrementum pteropi, the radix paeoniae rubrathe, the distillation of evodia rutaecarpa steam method, obtain crystal A;
Get the dregs of a decoction mixing surplus stock after distillation, then toward the ethanol that adds 95% in clear cream, mix and blend, makes it contain alcohol amount and reaches 70%, leaves standstill alcohol precipitation; Get supernatant and reclaim ethanol, collect mixture B;
3) crystal A and mixture B are mixed, be concentrated into thick paste shape medicinal extract, medicinal extract is pressed on nonwoven, make herbal application.
Embodiment 2:
A kind of Chinese medicine composition of GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus, be made up of oral medicament composition and externally-applied medicinal composition, described oral medicament composition is made up of the raw material of following weight portion: 8 parts of aspongopus, 15 parts of saline cistanches, 25 parts of Polygonum multiflower knotweeds, 25 parts of tetragonal crotalaria herbs, 18 parts of HERBA HEDYOTIS DIFFUSAEs, 20 parts of valerians, 12 parts of Fructus Aurantiis, 10 parts of the reds sage root, 12 parts of keel, 15 parts of PERIOSTRACUM CICADAEs;
Described externally-applied medicinal composition is made up of the raw material of following weight portion: 35 parts of excrementum pteropis, 30 parts of the radix paeoniae rubrathe, 30 parts of evodia rutaecarpas, 20 parts of the banksia rose, 10 parts of duck wheats.
The preparation method of described oral medicament composition comprises the following steps: get respectively each component raw material by described proportioning and pick up clean impurity elimination; all raw material stoving were pulverized 200 mesh sieves and were made powder; then mix by described proportioning, incapsulate or granulation or make tablet.
The preparation method of described externally-applied medicinal composition comprises the following steps:
1) raw material of externally-applied medicinal composition are crushed to respectively to 100 orders;
2) excrementum pteropi, the radix paeoniae rubrathe, the distillation of evodia rutaecarpa steam method, obtain crystal A;
Get the dregs of a decoction mixing surplus stock after distillation, then toward the ethanol that adds 95% in clear cream, mix and blend, makes it contain alcohol amount and reaches 70%, leaves standstill alcohol precipitation; Get supernatant and reclaim ethanol, collect mixture B;
3) crystal A and mixture B are mixed, be concentrated into thick paste shape medicinal extract, medicinal extract is pressed on nonwoven, make herbal application.
Embodiment 3:
A kind of Chinese medicine composition of GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus, be made up of oral medicament composition and externally-applied medicinal composition, described oral medicament composition is made up of the raw material of following weight portion: 6 parts of aspongopus, 11 parts of saline cistanches, 21 parts of Polygonum multiflower knotweeds, 20 parts of tetragonal crotalaria herbs, 14 parts of HERBA HEDYOTIS DIFFUSAEs, 16 parts of valerians, 9 parts of Fructus Aurantiis, 7 parts of the reds sage root, 8 parts of keel, 11 parts of PERIOSTRACUM CICADAEs;
Described externally-applied medicinal composition is made up of the raw material of following weight portion: 28 parts of excrementum pteropis, 22 parts of the radix paeoniae rubrathe, 22 parts of evodia rutaecarpas, 12 parts of the banksia rose, 6 parts of duck wheats.
The preparation method of described oral medicament composition comprises the following steps: get respectively each component raw material by described proportioning and pick up clean impurity elimination; all raw material stoving were pulverized 160 mesh sieves and were made powder; then mix by described proportioning, incapsulate or granulation or make tablet.
The preparation method of described externally-applied medicinal composition comprises the following steps:
1) raw material of externally-applied medicinal composition are crushed to respectively to 85 orders;
2) excrementum pteropi, the radix paeoniae rubrathe, the distillation of evodia rutaecarpa steam method, obtain crystal A;
Get the dregs of a decoction mixing surplus stock after distillation, then toward the ethanol that adds 95% in clear cream, mix and blend, makes it contain alcohol amount and reaches 70%, leaves standstill alcohol precipitation; Get supernatant and reclaim ethanol, collect mixture B;
3) crystal A and mixture B are mixed, be concentrated into thick paste shape medicinal extract, medicinal extract is pressed on nonwoven, make herbal application.
Embodiment 4:
A kind of Chinese medicine composition of GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus, be made up of oral medicament composition and externally-applied medicinal composition, described oral medicament composition is made up of the raw material of following weight portion: 7 parts of aspongopus, 14 parts of saline cistanches, 23 parts of Polygonum multiflower knotweeds, 23 parts of tetragonal crotalaria herbs, 17 parts of HERBA HEDYOTIS DIFFUSAEs, 19 parts of valerians, 10 parts of Fructus Aurantiis, 9 parts of the reds sage root, 10 parts of keel, 14 parts of PERIOSTRACUM CICADAEs; Described externally-applied medicinal composition is made up of the raw material of following weight portion: 33 parts of excrementum pteropis, 28 parts of the radix paeoniae rubrathe, 28 parts of evodia rutaecarpas, 18 parts of the banksia rose, 9 parts of duck wheats.
The preparation method of described oral medicament composition comprises the following steps: get respectively each component raw material by described proportioning and pick up clean impurity elimination; all raw material stoving were pulverized 190 mesh sieves and were made powder; then mix by described proportioning, incapsulate or granulation or make tablet.
The preparation method of described externally-applied medicinal composition comprises the following steps:
1) raw material of externally-applied medicinal composition are crushed to respectively to 95 orders;
2) excrementum pteropi, the radix paeoniae rubrathe, the distillation of evodia rutaecarpa steam method, obtain crystal A;
Get the dregs of a decoction mixing surplus stock after distillation, then toward the ethanol that adds 95% in clear cream, mix and blend, makes it contain alcohol amount and reaches 70%, leaves standstill alcohol precipitation; Get supernatant and reclaim ethanol, collect mixture B;
3) crystal A and mixture B are mixed, be concentrated into thick paste shape medicinal extract, medicinal extract is pressed on nonwoven, make herbal application.
Embodiment 5:
A kind of Chinese medicine composition of GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus, be made up of oral medicament composition and externally-applied medicinal composition, described oral medicament composition is made up of the raw material of following weight portion: aspongopus: 6.5 parts, and 12.5 parts of saline cistanches, 22.5 parts of Polygonum multiflower knotweeds, 21.5 parts of tetragonal crotalaria herbs, 15 parts of HERBA HEDYOTIS DIFFUSAEs, 17.5 parts of valerians, 10 parts of Fructus Aurantiis, 8 parts of the reds sage root, 9 parts of keel, 12.5 parts of PERIOSTRACUM CICADAEs; Described externally-applied medicinal composition is made up of the raw material of following weight portion: 30 parts of excrementum pteropis, 25 parts of the radix paeoniae rubrathe, 25 parts of evodia rutaecarpas, 15 parts of the banksia rose, 7.5 parts of duck wheats.
The preparation method of described oral medicament composition comprises the following steps: get respectively each component raw material by described proportioning and pick up clean impurity elimination; all raw material stoving were pulverized 180 mesh sieves and were made powder; then mix by described proportioning, incapsulate or granulation or make tablet.
The preparation method of described externally-applied medicinal composition comprises the following steps:
1) raw material of externally-applied medicinal composition are crushed to respectively to 90 orders;
2) excrementum pteropi, the radix paeoniae rubrathe, the distillation of evodia rutaecarpa steam method, obtain crystal A;
Get the dregs of a decoction mixing surplus stock after distillation, then toward the ethanol that adds 95% in clear cream, mix and blend, makes it contain alcohol amount and reaches 70%, leaves standstill alcohol precipitation; Get supernatant and reclaim ethanol, collect mixture B;
3) crystal A and mixture B are mixed, be concentrated into thick paste shape medicinal extract, medicinal extract is pressed on nonwoven, make herbal application.
Composition of the present invention, select the nontoxic Chinese medicinal herbs of pure ecology, so without any side effects, be exclusively used in the treatment of GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus, also can be used as meals and take throughout the year, the promoting circulation of blood of enriching blood, cleaning stomach, nourishing conditioning the five internal organs, strengthen physique, antibacterial virus killing, the generation of prevention digestive disease. Since two thousand seven, take patient's hundreds of medicine of the present invention, clinical practice proves, this medicine has evident in efficacy, instant effect, and the cycle is short, and cure rate is high, and rate is low repeatedly, have no side effect, lower-price characteristic. Test data sheet case 487 examples, the criterion of curative effect is: have significant curative effect: epimere oesophagus has no expansion, barium agent is by smooth; Recovery from illness: epimere oesophagus has no expansion, barium agent is by smoothly, subsequently without recurrence.
Stagnation of QI due to depression of the liver maga-esophagus treatment situation is as follows:
Model case one
Tall certain, female, 48 years old, the employee of Nanyang state-owned enterprise, dysphagia more than ten years, chest diaphragm ruffian is vexed, meets anger more very, pink tongue, tongue is thin, pulse condition string is thin, and double pantothenic acid, time weight when light. Hospital diagnosis is stagnation of QI due to depression of the liver maga-esophagus, takes inderal, nifepine so as to relief of symptoms, and hospital once intended operative treatment, does not give and adopting, small and wiry pulse, the thin Huang of the dark tongue of tongue and greasy. After hearing the news, come to seek medical advice on October 10th, 2008, take endo-medicine and the external used medicine that the present invention treats GI Medicine treatment stagnation of QI due to depression of the liver maga-esophagus and jointly use, wherein, the instructions of taking of endo-medicine: every day 2 times, each 2, every 9g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 30g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. Serve on two courses for the treatment of, transference cure, has no recurrence. Barivm meal fluoroscopy (screem): epimere oesophagus has no expansion, barium agent is by smooth.
Model case two
Clock, female, 39 years old. Before patient's three wheat harvesting periods, occur diet dysphagia, chest diaphragm ruffian is vexed, meets anger more very, pink tongue, tongue is thin, and pulse condition string is thin, and every day, food was little, and people becomes thin very much at present, does not defecate for a long time, can be before one day awareness of defecation continuous, almost can not leave toilet, but each only little by little, stool lake dress, yellow. Through alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, be diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 2 times, each 2, every 9g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 30g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. Treat after 1.5 courses for the treatment of, all oneself symptom disappear, and diet two is just all normal, recovery from illness.
Model case three
Hao, man, 41 years old. Patient is without conscious feed difficulty under obvious inducement before 5 years, and symptom increases the weight of gradually, and chest diaphragm ruffian is vexed, meets anger more very, pink tongue, and tongue is thin, and pulse condition string is thin, dysdipsia when serious. Through alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, be diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 2 times, each 2, every 9g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 30g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. 1 course for the treatment of, symptom obviously alleviates, and continues to take 1.5 courses for the treatment of, and disease obtains recovery from illness.
Model case three
Side certain, female, 35 years old. Choking feeling under breastbone while swallowing food, gastric disorder causing nausea, swallows and has some setbacks, vexed pain after breastbone, i.e. vomiting after food, stomach is dirty scorching hot, dry and hard excrement, tongue is red, and pulse condition string is thin, in conjunction with through alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, is diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 2 times, each 3, every 10g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 35g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. Treat after 1.5 courses for the treatment of, all oneself all diseases disappear, the peace of sleeping night and, diet two is just all normal, recovery from illness.
Model case four
Week certain, man, 47 years old, dysphagia, distending pain after breastbone, vomiting feel sick, drak urine, tongue fur is red, arteries and veins number. In conjunction with alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, be diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 3 times, each 3, every 12g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 33g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. 1 course for the treatment of, symptom obviously alleviates, and continues to take 1 course for the treatment of, and disease obtains recovery from illness.
Model case five
Wang, female, 35 years old. Patient nearly February choking feeling under breastbone when swallowing food, gastric disorder causing nausea, swallows and has some setbacks, vexed pain after breastbone, anti-food, spiritlessness and weakness, receives few, pink tongue, tongue is thin, and arteries and veins is thin, often because mood excitation symptom increases the weight of, through alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, be diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 3 times, each 3, every 12g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 33g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. Treat after 1.5 courses for the treatment of, all oneself all diseases disappear, the peace of sleeping night and, diet two is just all normal, recovery from illness.
Model case six
Zhao, man, 47 years old, readme dysphagia, distending pain after breastbone, scorching hot, nauseating, tongue is red, thready and weak pulse without strength. In conjunction with alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, be diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 3 times, each 3, every 12g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 33g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. 1 course for the treatment of, symptom obviously alleviates, and continues to take 1.5 courses for the treatment of, and disease obtains recovery from illness.
Model case seven
Beam, female, 33 years old. Choking feeling under breastbone when cause is swallowed food, gastric disorder causing nausea, swallows and has some setbacks, vexed pain after breastbone, the gastric disorder causing nausea of feeling sick, spiritlessness and weakness, receives less, and yellowish fur, meets anger more very, pink tongue, tongue is thin, and pulse condition string is thin, in conjunction with through alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, is diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 3 times, each 3, every 12g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 33g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether. Treat after 1.5 courses for the treatment of, all oneself all diseases disappear, the peace of sleeping night and, diet two is just all normal, recovery from illness.
Model case 8
Pei, man, 42 years old, dysphagia, distending pain after breastbone, vomiting is felt sick, yellowish fur, pulse condition string is thin. In conjunction with alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, be diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Take the Chinese medicine composition that the present invention treats maga-esophagus and treat, the instructions of taking of endo-medicine: every day 3 times, each 3, every 12g, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, and paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 32g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether, and good synergy is played in for oral administration and external application, 1 course for the treatment of, symptom obviously alleviates, and continues to take 1.5 courses for the treatment of, and disease obtains recovery from illness.
Model case 8
Model case 9
Flood certain, man, 42 years old, dysphagia, distending pain after breastbone, vomiting feel sick, yellowish fur, pulse condition string is thin. In conjunction with alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, the state of an illness roughly the same () with model case 8 Pei, is diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Taking the Chinese medicine composition that the present invention treats maga-esophagus treats, the instructions of taking of endo-medicine: every day 3 times, each 3 of morning, noon and afternoon, every 12g, powder is capsule, the difference of capsule and model case 8 is: the capsule of case 9 is provided with interior capsule in being, interior capsule packs 4g endo-medicine into, cavity between capsule and interior capsule packs 8g endo-medicine into, the endo-medicine amount of case 9 and case 8 is identical, but double-deck capsule long action time in human body, drug effect is fully utilized, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, and paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 32g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether, and good synergy is played in for oral administration and external application, uses after 20 days, symptom obviously alleviates, and continues to take disease after 10 days and obtains recovery from illness.
Model case 10
Week certain, man, 43 years old, dysphagia, distending pain after breastbone, vomiting feel sick, yellowish fur, pulse condition string is thin. In conjunction with alimentary canal barivm meal fluoroscopy (screem) and gastrocopy, the state of an illness is more serious than model case 8 Pei's the state of an illness, is diagnosed as stagnation of QI due to depression of the liver maga-esophagus. Taking the Chinese medicine composition that the present invention treats maga-esophagus treats, the instructions of taking of endo-medicine: every day 3 times, each 3 of morning, noon and afternoon, every 12g, powder is capsule, the difference of capsule and model case 8 is: the capsule of case 9 is provided with interior capsule in being, interior capsule packs 4g endo-medicine into, cavity between capsule and interior capsule packs 8g endo-medicine into, the endo-medicine amount of case 9 and case 8 is identical, but double-deck capsule long action time in human body, drug effect is fully utilized, 30 days courses for the treatment of; The using method of external used medicine: external used medicine need be synchronizeed and use with innerlich anwenden thing, at Qihai, too punching, Zusanli, 4 acupuncture points of Yanglingquan stick, and paste at each position one, paste and take off after 24 hours, take off after 4 days and paste again 1 time, every note 32g, 30 days courses for the treatment of, a course for the treatment of, 24 subsides were pasted at 4 positions altogether, and good synergy is played in for oral administration and external application, uses after 20 days, symptom obviously alleviates, and continues to take disease after 15 days and obtains recovery from illness.

Claims (3)

1. treat the Chinese medicine composition of stagnation of QI due to depression of the liver maga-esophagus for one kind, it is characterized in that: be made up of oral medicament composition and externally-applied medicinal composition, described oral medicament composition is made up of the raw material of following weight portion: 5~8 parts of aspongopus, 10~15 parts of saline cistanches, 20~25 parts of Polygonum multiflower knotweeds, 18~25 parts of tetragonal crotalaria herbs, 12~18 parts of HERBA HEDYOTIS DIFFUSAEs, 15~20 parts of valerians, 8~12 parts of Fructus Aurantiis, 6~10 parts of the reds sage root, 6~12 parts of keel, 10~15 parts of PERIOSTRACUM CICADAEs;
Described externally-applied medicinal composition is made up of the raw material of following weight portion: 25~35 parts of excrementum pteropis, 20~30 parts of the radix paeoniae rubrathe, 20~30 parts of evodia rutaecarpas, 10~20 parts of the banksia rose, 5~10 parts of duck wheats.
2. the Chinese medicine composition for the treatment of stagnation of QI due to depression of the liver maga-esophagus as claimed in claim 1, it is characterized in that: described oral medicament composition is made up of the raw material of following weight portion: 6 parts of aspongopus, 11 parts of saline cistanches, 21 parts of Polygonum multiflower knotweeds, 20 parts of tetragonal crotalaria herbs, 14 parts of HERBA HEDYOTIS DIFFUSAEs, 16 parts of valerians, 9 parts of Fructus Aurantiis, 7 parts of the reds sage root, 8 parts of keel, 11 parts of PERIOSTRACUM CICADAEs; Described externally-applied medicinal composition is made up of the raw material of following weight portion: 28 parts of excrementum pteropis, 22 parts of the radix paeoniae rubrathe, 22 parts of evodia rutaecarpas, 12 parts of the banksia rose, 6 parts of duck wheats.
3. the preparation method of the Chinese medicine composition for the treatment of stagnation of QI due to depression of the liver maga-esophagus as claimed in claim 1, it is characterized in that: the preparation method of described oral medicament composition comprises the following steps: get respectively each component raw material by described proportioning and pick up clean impurity elimination, all raw material stoving were pulverized 150~200 mesh sieves and were made powder, then mix by described proportioning, incapsulate or granulation or make tablet; The preparation method of described externally-applied medicinal composition comprises the following steps:
1) raw material of externally-applied medicinal composition are crushed to respectively to 80~100 orders;
2) excrementum pteropi, the radix paeoniae rubrathe, the distillation of evodia rutaecarpa steam method, obtain crystal A;
Get the dregs of a decoction mixing surplus stock after distillation, then toward the ethanol that adds 95% in clear cream, mix and blend, makes it contain alcohol amount and reaches 70%, leaves standstill alcohol precipitation; Get supernatant and reclaim ethanol, collect mixture B;
3) crystal A and mixture B are mixed, be concentrated into thick paste shape medicinal extract, medicinal extract is pressed on nonwoven, make herbal application.
CN201610004833.4A 2016-01-07 2016-01-07 Traditional Chinese medicine composition for treating achalsaia caused by liver depression and qi stagnation and preparation method thereof Pending CN105596519A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1465387A (en) * 2002-06-24 2004-01-07 秦旭东 Chinese medicine preparation for treating carcinoma of esophagus
CN103405715A (en) * 2013-07-29 2013-11-27 孙春梅 Traditional Chinese medicine composite used for treating achalasia of cardia
CN104435579A (en) * 2014-12-15 2015-03-25 刘福国 Traditional Chinese medicine for treating liver depression and qi stagnation type cardia achalasia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1465387A (en) * 2002-06-24 2004-01-07 秦旭东 Chinese medicine preparation for treating carcinoma of esophagus
CN103405715A (en) * 2013-07-29 2013-11-27 孙春梅 Traditional Chinese medicine composite used for treating achalasia of cardia
CN104435579A (en) * 2014-12-15 2015-03-25 刘福国 Traditional Chinese medicine for treating liver depression and qi stagnation type cardia achalasia

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Title
盛军: "中药配合化疗治疗中晚期食管癌30例", 《四川中医》 *

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