CN101543616B - Traditional Chinese medicine composition for preventing and treating tumor and its preparation method - Google Patents
Traditional Chinese medicine composition for preventing and treating tumor and its preparation method Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for preventing and treating tumor and its preparation method. The composition is composed of effective ingredient or effective ingredient with pharmaceutically acceptable carrier; the effective ingredient is prepared from Astragalus root, Szechuan Lovage Rhizome and Safflower etc. The traditional Chinese medicine composition can prevent and treat all kinds of tumors and malignant tumors in effective rate of more than 75 percent. A experiment shows non-toxic effect of the composition.
Description
[technical field]
The present invention relates to technical field of Chinese medicines, more specifically, the present invention relates to a kind of Chinese medicine composition of anti-curing oncoma, also relate to the method for preparing of the Chinese medicine composition of preventing and treating tumor of addressing.
[background technology]
Tumor is that a kind of grievous injury people are healthy, the disease that jeopardizes people's life.At present, cancer treatment method has operative treatment, radiotherapy, chemotherapy etc.Operative treatment is a kind of treatment tumor method commonly used; Radiation and chemotherapy is the most popular method that cooperates the operative treatment tumor, and these Therapeutic Method have been obtained rapid progress, but with regard to reality; Also there are many limitation in these methods, can't satisfy actual needs.
China's Chinese medicine and pharmacy is with a long history, and clinical experience is abundant, and unique medical system is arranged.The traditional Chinese medical science has been brought into play significant role according to the body resistance strengthening and constitution consolidating, activating blood circulation to dissipate blood stasis, heat-clearing and toxic substances removing, hard masses softening and resolving four big rules in the treatment tumor.At present, the Chinese medicine patent or the patent application of the existing a large amount of relevant treatment tumors of China, these achievements show; Adopt Chinese traditional treatment can strengthen or adjust the resistance against diseases of whole machine body; The main human body immunity improving function of passing through is improved the body self-healing ability, improves the ability of the anti-radiotherapy of human body, chemical therapy toxic side effect; The tolerance of enhancing body, thereby the cure rate of raising tumor.
The inventor finds that also there are some problems in Chinese medicine at present, does not also give full play to the advantage of Chinese medicine in a large amount of clinical practices.Therefore, also the inventor furthers investigate, and obtains good result, has made Chinese medicine composition the present invention of anti-curing oncoma finally, and said composition is referred to as " tumor dissipation " usually.
[summary of the invention]
[technical problem that will solve]
The Chinese medicine composition that the purpose of this invention is to provide a kind of anti-curing oncoma.
Another object of the present invention provides the method for preparing of the Chinese medicine composition of said anti-curing oncoma.
[technical scheme]
The present invention realizes through following technical proposals.
The present invention prepares according to " monarch " Chinese medicine general principle.Call in " interior warp, sink greatly " book, the medicine meaning monarch of main disease, assistant monarch's medicine meaning minister is answered the medicine of minister to call and is made.The present invention is according to this traditional Chinese medical science general principle, is the prescription that main formula basis proposes with gas, blood, yin, yang, and this prescription is generous, the compound recipe of the traditional Chinese medical science, from multi-angle system side, with the intricate property that adapts to disease and many characteristics of human body self.
The present invention relates to a kind of Chinese medicine composition of anti-curing oncoma, it is made up of effective ingredient or effective ingredient and pharmaceutically acceptable carrier, it is characterized in that said effective ingredient processed by following raw materials according:
The total side 29-37 of nourshing blood and promoting blood circulation weight portion; The total side 26-32 of anti-inflammatory analgetic weight portion;
Removing mass total side 84-150 weight portion of subsiding a swelling; The total side 60-66 of removing blood stasis with potent drugs expectorant weight portion;
Scolopendra 2-4 weight portion; Concha Arcae 17-23 weight portion;
Scorpio 2-6 weight portion; The mountain is aunt 10-14 weight portion now;
Periostracum Serpentis 2-6 weight portion; Herba Scutellariae Barbatae 17-23 weight portion;
Herba Lobeliae Chinensis 15-21 weight portion; Ophicalcitum 2-8 weight portion;
The total side of described nourshing blood and promoting blood circulation is made up of the 12-18 weight portion Radix Astragali, 9-15 weight portion Rhizoma Chuanxiong and 4-8 weight portion Flos Carthami;
The total side of described anti-inflammatory analgetic is made up of 7-11 weight Nidus Vespae, 7-11 weight Radix Sophorae Tonkinensis, 4-8 weight Semen Strychni and 3-7 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 40-50 weight portion Fructus Aurantii, 40-50 weight portion Fructus Aurantii Immaturus, 15-21 weight portion WULINGZI, 24-30 weight portion radix curcumae and 7-11 weight portion Sal Nitri;
The total side of described removing blood stasis with potent drugs expectorant is made up of 24-30 weight portion Alumen, 27-33 weight portion Herba Agrimoniae and 7-11 weight portion Resina Toxicodendri.
Preferably, said effective ingredient is processed by following raw materials according:
The total side 32-35 of nourshing blood and promoting blood circulation weight portion; The total side 28-30 of anti-inflammatory analgetic weight portion;
Removing mass total side 94-130 weight portion of subsiding a swelling; The total side 62-64 of removing blood stasis with potent drugs expectorant weight portion;
Scolopendra 2-4 weight portion; Concha Arcae 18-22 weight portion;
Scorpio 2-5 weight portion; The mountain is aunt 11-13 weight portion now;
Periostracum Serpentis 2-5 weight portion; Herba Scutellariae Barbatae 18-22 weight portion;
Herba Lobeliae Chinensis 16-18 weight portion; Ophicalcitum 2-6 weight portion;
The total side of described nourshing blood and promoting blood circulation is made up of the 14-16 weight portion Radix Astragali, 10-14 weight portion Rhizoma Chuanxiong and 5-8 weight portion Flos Carthami;
The total side of described anti-inflammatory analgetic is made up of 8-10 weight Nidus Vespae, 8-10 weight Radix Sophorae Tonkinensis, 5-8 weight Semen Strychni and 4-6 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 45-48 weight portion Fructus Aurantii, 42-48 weight portion Fructus Aurantii Immaturus, 16-20 weight portion WULINGZI, 26-28 weight portion radix curcumae and 8-10 weight portion Sal Nitri;
The total side of described removing blood stasis with potent drugs expectorant is made up of 26-28 weight portion Alumen, 28-32 weight portion Herba Agrimoniae and 8-10 weight portion Resina Toxicodendri.
More preferably, said effective ingredient is processed by following raw materials according:
The total side of nourshing blood and promoting blood circulation 33 weight portions; The total side of anti-inflammatory analgetic 29 weight portions;
The total side of removing mass detumescence 114 weight portions; The total side of removing blood stasis with potent drugs expectorant 63 weight portions;
Scolopendra 3 weight portions; Concha Arcae 20 weight portions;
Scorpio 4 weight portions; The mountain is aunt's 12 weight portions now;
Periostracum Serpentis 4 weight portions; Herba Scutellariae Barbatae 20 weight portions;
Herba Lobeliae Chinensis 18 weight portions; Ophicalcitum 6 weight portions;
The total side of described nourshing blood and promoting blood circulation is made up of the 15 weight portion Radixs Astragali, 12 weight portion Rhizoma Chuanxiongs and 6 weight portion Flos Carthamis;
The total side of described anti-inflammatory analgetic is made up of 9 weight Nidus Vespaes, 9 weight Radix Sophorae Tonkinensiss, 6 weight Semen Strychni and 5 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 45 weight portion Fructus Aurantiis, 45 weight portion Fructus Aurantii Immaturuss, 18 weight portion WULINGZI, 27 weight portion radix curcumaes and 9 weight portion Sal Nitris;
The total side of described removing blood stasis with potent drugs expectorant is made up of 27 weight portion Alumen, 30 weight portion Herba Agrimoniaes and 9 weight portion Resina Toxicodendri.
According to one embodiment of the present invention, the Chinese medicine composition of anti-curing oncoma of the present invention is granule, capsule, tablet, pill or oral liquid.
The invention still further relates to the method for preparing of said Chinese medicine composition, it is characterized in that this method comprises the steps:
A, raw materials of traditional Chinese medicinal materials according to claim 1 wash, dry, pulverize 100 purpose fine powders respectively;
B, taking by weighing in steps A according to the described raw materials of traditional Chinese medicinal materials consumption of claim 1) each raw materials of traditional Chinese medicinal materials fine powder of obtaining is as active component;
C, with above-mentioned active component with processing various dosage forms pharmaceutically can accepting carrier.
According to one embodiment of the present invention, this method also is included in steps A) the raw materials of traditional Chinese medicinal materials powder that obtains temperature 115-120 ℃ with pressure 0.2-0.3MPa condition under sterilization 30-35 minute.
Below the present invention will be described at length.
The present invention relates to a kind of Chinese medicine composition of anti-curing oncoma, it is made up of effective ingredient or effective ingredient and pharmaceutically acceptable carrier, it is characterized in that said effective ingredient processed by following raw materials according:
The total side 29-37 of nourshing blood and promoting blood circulation weight portion; The total side 26-32 of anti-inflammatory analgetic weight portion;
Removing mass total side 84-150 weight portion of subsiding a swelling; The total side 60-66 of removing blood stasis with potent drugs expectorant weight portion;
Scolopendra 2-4 weight portion; Concha Arcae 17-23 weight portion;
Scorpio 2-6 weight portion; The mountain is aunt 10-14 weight portion now;
Periostracum Serpentis 2-6 weight portion; Herba Scutellariae Barbatae 17-23 weight portion;
Herba Lobeliae Chinensis 15-21 weight portion; Ophicalcitum 2-8 weight portion;
The total side of described nourshing blood and promoting blood circulation is made up of the 12-18 weight portion Radix Astragali, 9-15 weight portion Rhizoma Chuanxiong and 4-8 weight portion Flos Carthami;
The total side of described anti-inflammatory analgetic is made up of 7-11 weight Nidus Vespae, 7-11 weight Radix Sophorae Tonkinensis, 4-8 weight Semen Strychni and 3-7 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 40-50 weight portion Fructus Aurantii, 40-50 weight portion Fructus Aurantii Immaturus, 15-21 weight portion WULINGZI, 24-30 weight portion radix curcumae and 7-11 weight portion Sal Nitri;
The total side of described removing blood stasis with potent drugs expectorant is made up of 24-30 weight portion Alumen, 27-33 weight portion Herba Agrimoniae and 7-11 weight portion Resina Toxicodendri.
In technique scheme, a part of Chinese crude drug effect is following:
Fructus Aurantii and Fructus Aurantii Immaturus nature and flavor: bitter, acid, cold-resistant; Its effect: the dispelling the stagnated QI removing food stagnancy, be applied to control chest and diaphragm expectorant and stagnate, the feeling of stuffiness in chest, the side of body expands, food stagnation, eructation, vomiting, heavy behind the dysentery, proctoptosis, uterine prolapse.
Semen Strychni nature and flavor: bitter, cold, very toxic; Its effect: the Lip river of stimulating the menstrual flow, swollen, the pain relieving of knot that disappears, be applied to pathogenic wind toxic and scurry through, contracture pain, traumatic injury, fracture, hemiplegia, brothers are unable, facial paralysis, tuberculous lymphadenitis, poliomyelitis sequela, all carcinoma, and external is controlled skin carcinoma, carbuncle furuncle furuncle etc.
Radix curcumae nature and flavor: hot, bitter, cold; Its effect: promoting QI circulation for relieving depression, the removing heat from blood removing blood stasis with potent drugs, soothing the liver, gallbladder, happy key is applied to depression of liver-QI, hypochondriac pain uncomfortable in chest, the stomach abdominal distention and pain, jaundice, heat in blood stasis is spitted blood, hematuria, epilepsy, dysmenorrhea, menoxenia, carbuncle and hygropyrexia expectorant is turbid hoodwinks disease such as thinking.
The Sal Nitri nature and flavor: bitter, cold, nontoxic, its effect: removing mass, it is hard to loose, blood circulation promoting and blood stasis dispelling, diuresis, detumescence, and can change the 72 kinds of stones and the five metals that disappears, and be applied to the long-pending heat of the five internal organs, remove to hold the knot diet.Control inflammation of the throat, gastric fullness, abdominal distention, constipation, the cholera vomiting and diarrhea, furious headache, toothache, scrofula, women labor is deceived subcutaneous ulcer, stomach abdomen pain, pneumonia, pleuritis, various edema and stranguria caused by urinary stone, various calculus, diseases such as carcinoma.
The Radix Sophorae Tonkinensis nature and flavor: bitter, cold, its effect: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, sharp larynx of eliminating stagnation and relieving constipation etc. are applied to acute laryngopharyngitis; The pyretic toxicity knot gathers tonsillitis, swelling and sore throat, gingival swelling and pain; The cough due to lung-heat, jaundice due to damp-heat, carbuncle furuncle and phyma poison, diseases such as constipation and carcinoma.
Radix Astragali nature and flavor: sweet, tepor, its effect: strong nourishing, tonifying Qi and lifting yang, nourishing kidney spleen reinforcing, strengthening superficial resistance to stop perspiration, the evacuation of pus of holder skin ulcer; Detumescence and promoting granulation, diuretic etc. are applied to the empty spontaneous perspiration of body, deficiency of vital energy edema, mental weariness, chronic diarrhea proctoptosis; Deficiency of vital energy insufficiency of blood, sinking of QI of middle-JIAO, gastroptosis, chronic ulcer, uterine prolapse, metrorrhagia; Chronic nephritis is quenched one's thirst, carbuncle, and skin ulcer is swollen, festers, and does not close up for a long time and various carcinoma.
The Nidus Vespae nature and flavor: bitter, salty, or sweet, flat.Poisonous, its effect: wind dispelling insecticide, detoxifcation counteracting toxic substances, relieving convulsion blood stasis dispelling, diuresis hemostasis; The swollen analgesic therapy of loosing, is reduced phlegm and Xing Yang etc. at heart tonifying, and it is painful to be applied to the wind dental caries, headache, pertussis; Sore swollen toxin, mastitis, lymph gland or bone tuberculosis, stubborn dermatitis malignant boil, frightened convulsion migratory arthralgia; The turbid band of metrorrhagia, the sexual impotence enuresis, swollen joint is painful, diseases such as rheumatism and rheumatoid arthrosis deadlock are swollen, carcinoma.
Scolopendra nature and flavor: suffering, temperature.Poisonous, its effect spasmolytic relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and detoxifcation is applied to tetanus, infantile convulsion, and epilepsy, spasm is twitched, opisthotonus, locked mouth; Facial paralysis, sore swollen toxin, chronic osteomyelitis, multiple furuncle and phyma, acute mastitis, chronic ulcer, diseases such as trauma infection contamination tuberculosis and carcinoma.
The Concha Arcae nature and flavor: sweet, salty, flat, its effect: hard masses softening and resolving, the antacid of reducing phlegm is applied to hyperchlorhydria, the long-pending piece of blood stasis, diseases such as gastric and duodenal ulcers, carcinoma.
Resina Toxicodendri is the dry product of Anacardiaceae plant Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) resin after processing, and nature and flavor are hot, and temperature is poisonous, its effect removing blood stasis with potent drugs, and removing food stagnancy, parasite killing is used to control women's amenorrhea ， mass in the abdomen, blood stasis, malnutrition due to parasitic infestation.
The Chinese medicine composition of the anti-curing oncoma of the present invention can be processed the conventional dosage form for oral administration that makes preparations for sowing with above-mentioned raw materials and at pharmaceutically acceptable carrier or excipient.
The Chinese medicine composition of the anti-curing oncoma of the present invention can directly be pulverized as the active component of treatment tumor.Described active component also can with process various pharmaceutical formulations for oral administration such as powder, pill, tablet, granule, capsule, oral liquid etc. in pharmaceutically acceptable carrier or excipient composition.Wherein said pharmaceutically acceptable carrier or excipient are normally used carrier or excipient in Chinese medicine preparation, for being to select easily to confirm for the technical staff in pharmaceutical technology field.
Preferably, said effective ingredient is processed by following raw materials according:
The total side 32-35 of nourshing blood and promoting blood circulation weight portion; The total side 28-30 of anti-inflammatory analgetic weight portion;
Removing mass total side 94-130 weight portion of subsiding a swelling; The total side 62-64 of removing blood stasis with potent drugs expectorant weight portion;
Scolopendra 2-4 weight portion; Concha Arcae 18-22 weight portion;
Scorpio 2-5 weight portion; The mountain is aunt 11-13 weight portion now;
Periostracum Serpentis 2-5 weight portion; Herba Scutellariae Barbatae 18-22 weight portion;
Herba Lobeliae Chinensis 16-18 weight portion; Ophicalcitum 2-6 weight portion;
The total side of described nourshing blood and promoting blood circulation is made up of the 14-16 weight portion Radix Astragali, 10-14 weight portion Rhizoma Chuanxiong and 5-8 weight portion Flos Carthami;
The total side of described anti-inflammatory analgetic is made up of 8-10 weight Nidus Vespae, 8-10 weight Radix Sophorae Tonkinensis, 5-8 weight Semen Strychni and 4-6 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 45-48 weight portion Fructus Aurantii, 42-48 weight portion Fructus Aurantii Immaturus, 16-20 weight portion WULINGZI, 26-28 weight portion radix curcumae and 8-10 weight portion Sal Nitri;
The total side of described removing blood stasis with potent drugs expectorant is made up of 26-28 weight portion Alumen, 28-32 weight portion Herba Agrimoniae and 8-10 weight portion Resina Toxicodendri.
More preferably, said effective ingredient is processed by following raw materials according:
The total side of nourshing blood and promoting blood circulation 33 weight portions; The total side of anti-inflammatory analgetic 29 weight portions;
The total side of removing mass detumescence 114 weight portions; The total side of removing blood stasis with potent drugs expectorant 63 weight portions;
Scolopendra 3 weight portions; Concha Arcae 20 weight portions;
Scorpio 4 weight portions; The mountain is aunt's 12 weight portions now;
Periostracum Serpentis 4 weight portions; Herba Scutellariae Barbatae 20 weight portions;
Herba Lobeliae Chinensis 18 weight portions; Ophicalcitum 6 weight portions;
The total side of described nourshing blood and promoting blood circulation is made up of the 15 weight portion Radixs Astragali, 12 weight portion Rhizoma Chuanxiongs and 6 weight portion Flos Carthamis;
The total side of described anti-inflammatory analgetic is made up of 9 weight Nidus Vespaes, 9 weight Radix Sophorae Tonkinensiss, 6 weight Semen Strychni and 5 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 45 weight portion Fructus Aurantiis, 45 weight portion Fructus Aurantii Immaturuss, 18 weight portion WULINGZI, 27 weight portion radix curcumaes and 9 weight portion Sal Nitris;
The total side of described removing blood stasis with potent drugs expectorant is made up of 27 weight portion Alumen, 30 weight portion Herba Agrimoniaes and 9 weight portion Resina Toxicodendri.
According to one embodiment of the present invention, the Chinese medicine composition of anti-curing oncoma of the present invention is granule, capsule, tablet, pill or oral liquid.
The invention still further relates to the method for preparing of said Chinese medicine composition, it is characterized in that this method comprises the steps:
A, raw materials of traditional Chinese medicinal materials according to claim 1 wash, dry, are crushed to 100 purpose fine powders respectively.
Described raw materials of traditional Chinese medicinal materials need at first be removed mouldy septic medical material, removes impurity, uses water washing then, and filter is done, and uses the Chinese crude drug dehydrator of on market, selling at present to dry then.
The Chinese crude drug pulverizer that raw materials of traditional Chinese medicinal materials reuse after the oven dry is sold on market is at present pulverized, and obtains 100 purpose raw materials of traditional Chinese medicinal materials fine powders through the screening of 100 eye mesh screens.
B, taking by weighing in steps A according to the described raw materials of traditional Chinese medicinal materials consumption of claim 1) each raw materials of traditional Chinese medicinal materials fine powder of obtaining is as active component;
C, with above-mentioned active component with processing various dosage forms pharmaceutically can accepting carrier.
Described is normally used carrier in Chinese medicine preparation at pharmaceutically acceptable carrier, for being to select easily to confirm for the technical staff in pharmaceutical technology field.
According to one embodiment of the present invention, this method also is included in steps A) the raw materials of traditional Chinese medicinal materials powder that obtains temperature 115-120 ℃ with pressure 0.2-0.3MPa condition under sterilization 30-35 minute.
[beneficial effect]
Chinese medicine composition of the present invention has removing blood stasis and activating blood flow, the removing mass of assaulting fortified position, pain relieving granulation promoting, eliminating inflammation and expelling toxin, refreshment and brain nourishing, the poison detumescence of dispelling, promoting blood circulation, the wide intestinal of promoting the circulation of QI, the effect of the thin stagnant painful abdominal mass that disappears.Can weed out the old and bring forth the new strong nerve, the composition structure and the nutrition rehabilitation of promotion tissue and cell, enhancing body and anti-virus ability; Eliminate harmful reflection of pathogenic factor, strengthening vital QI to eliminate pathogenic factors makes cancerous cell produce regression and changes; Or gross tumor volume is dwindled or disappear, or cancerous cell is melted, from body, disappear.This Chinese medicine composition is 75% to the total effective rate of preventing and treating various tumors and malignant tumor, and test shows and has no side effect.Particularly to the early discovery carcinoma, medication is in time reasonably taken good care of and is nursed, and good focus improvement has all taken place and obtained good curative effect.
[specific embodiment]
Embodiment 1
Take by weighing the 100 order raw materials of traditional Chinese medicinal materials of handling according to the inventive method according to following dosage:
Scolopendra 3 gram Concha Arcaes 20 gram Scorpios 4 Keshans are aunt's 12 grams now
Periostracum Serpentis 4 gram Herba Scutellariae Barbataes 20 gram Herba Lobeliae Chinensis 18 gram Ophicalcitums 6 grams
The Radix Astragali 15 gram Rhizoma Chuanxiongs 12 gram Flos Carthamis 6 gram Nidus Vespaes 9 grams
Radix Sophorae Tonkinensis 9 KEMA Semen Strychni 6 gram LIAOJIANGSHI 5 gram Fructus Aurantiis 45 grams
Fructus Aurantii Immaturus 45 gram WULINGZI 18 gram radix curcumaes 27 gram Sal Nitris 9 grams
Alumen 27 gram Herba Agrimoniaes 30 gram Resina Toxicodendri 9 grams
Above-mentioned raw materials Chinese crude drug fine powder mix homogeneously is processed conventional oral medicine powde dosage form.
Embodiment 2
Take by weighing the 100 order raw materials of traditional Chinese medicinal materials of handling according to the inventive method according to following dosage:
Scolopendra 2.1 gram Concha Arcaes 21.5 gram Scorpios 4.5 Keshans are aunt's 11.5 grams now
Periostracum Serpentis 4.5 gram Herba Scutellariae Barbataes 21.0 gram Herba Lobeliae Chinensis 19.0 gram Ophicalcitums 6.2 grams
The Radix Astragali 15.2 gram Rhizoma Chuanxiongs 11.6 gram Flos Carthamis 5.8 gram Nidus Vespaes 9.4 grams
Radix Sophorae Tonkinensis 9.2 KEMA Semen Strychni 5.8 gram LIAOJIANGSHI 4.6 gram Fructus Aurantiis 42 grams
Fructus Aurantii Immaturus 42 gram WULINGZI 20 gram radix curcumaes 28 gram Sal Nitris 8.6 grams
The capsule for medicine of packing into behind the Alumen 27.2 gram Herba Agrimoniaes 29.5 gram Resina Toxicodendri 8.0 gram above-mentioned raw materials Chinese crude drug fine powder mix homogeneously is processed capsule formulation.
Embodiment 3
Take by weighing the 100 order raw materials of traditional Chinese medicinal materials of handling according to the inventive method according to following dosage:
Scolopendra 3.1 gram Concha Arcaes 18.5 gram Scorpios 5.5 Keshans are aunt's 13.5 grams now
Periostracum Serpentis 5.5 gram Herba Scutellariae Barbataes 23.0 gram Herba Lobeliae Chinensis 20.0 gram Ophicalcitums 7.2 grams
The Radix Astragali 16.2 gram Rhizoma Chuanxiongs 13.6 gram Flos Carthamis 7.5 gram Nidus Vespaes 9.4 grams
Radix Sophorae Tonkinensis 9.2 KEMA Semen Strychni 6.2 gram LIAOJIANGSHI 6.0 gram Fructus Aurantiis 46.0 grams
Fructus Aurantii Immaturus 46.2 gram WULINGZI 19.5 gram radix curcumaes 24.2 gram Sal Nitris 10.6 grams
Alumen 24.2 gram Herba Agrimoniaes 30.8 gram Resina Toxicodendri 10.1 grams
Method for preparing is identical with embodiment 1.
Embodiment 4
Take by weighing the 100 order raw materials of traditional Chinese medicinal materials of handling according to the inventive method according to following dosage:
Scolopendra 2.1 gram Concha Arcaes 22.5 gram Scorpios 4.5 Keshans are aunt's 10.5 grams now
Periostracum Serpentis 2.5 gram Herba Scutellariae Barbataes 18.9 gram Herba Lobeliae Chinensis 20.0 gram Ophicalcitums 3.2 grams
The Radix Astragali 13.2 gram Rhizoma Chuanxiongs 11.6 gram Flos Carthamis 4.9 gram Nidus Vespaes 9.4 grams
Radix Sophorae Tonkinensis 9.0 KEMA Semen Strychni 5.6 gram LIAOJIANGSHI 3.6 gram Fructus Aurantiis 42 grams
Fructus Aurantii Immaturus 42 gram WULINGZI 16.5 gram radix curcumaes 29.2 gram Sal Nitris 8.6 grams
Alumen 28.2 gram Herba Agrimoniaes 27.8 gram Resina Toxicodendri 8.1 grams
Method for preparing is identical with embodiment 1.
Embodiment 5
Take by weighing the 100 order raw materials of traditional Chinese medicinal materials of handling according to the inventive method according to following dosage:
Scolopendra 2.8 gram Concha Arcaes 21.5 gram Scorpios 3.5 Keshans are aunt's 13.5 grams now
Periostracum Serpentis 4.5 gram Herba Scutellariae Barbataes 22.9 gram Herba Lobeliae Chinensis 16.0 gram Ophicalcitums 7.2 grams
The Radix Astragali 13.0 gram Rhizoma Chuanxiongs 10.8 gram Flos Carthamis 5.9 gram Nidus Vespaes 8.6 grams
Radix Sophorae Tonkinensis 9.2 KEMA Semen Strychni 5.6 gram LIAOJIANGSHI 6.6 gram Fructus Aurantiis 43 grams
Fructus Aurantii Immaturus 43 gram WULINGZI 20.5 gram radix curcumaes 25.2 gram Sal Nitris 8.6 grams
Bright 27.2 gram Herba Agrimoniaes, 28.8 gram Resina Toxicodendri, 8.2 grams
Method for preparing is identical with embodiment 1.
Embodiment 6
Take by weighing the 100 order raw materials of traditional Chinese medicinal materials of handling according to the inventive method according to following dosage:
Scolopendra 2.8 gram Concha Arcaes 21.5 gram Scorpios 3.5 Keshans are aunt's 13.5 grams now
Periostracum Serpentis 4.5 gram Herba Scutellariae Barbataes 22.9 gram Herba Lobeliae Chinensis 16.0 gram Ophicalcitums 7.2 grams
The Radix Astragali 17.0 gram Rhizoma Chuanxiongs 9.8 gram Flos Carthamis 4.9 gram Nidus Vespaes 8.6 grams
Radix Sophorae Tonkinensis 10.2 KEMA Semen Strychni 5.6 gram LIAOJIANGSHI 6.1 gram Fructus Aurantiis 48 grams
Fructus Aurantii Immaturus 40 gram WULINGZI 19.5 gram radix curcumaes 28.2 gram Sal Nitris 8.6 grams
Alumen 26.2 gram Herba Agrimoniaes 28.0 gram Resina Toxicodendri 9.2 grams
Method for preparing is identical with embodiment 1.
Clinical trial experimental example 1:
The anti-curing oncoma Chinese medicine composition of the embodiment of the invention 1 is to the clinical efficacy of various benign tumors, malignant tumor.
One, object of study
34 examples are suffered from benign tumors and malignant tumor late period, male 19 example age 38-78 year wherein, women 16 example age 39-65 year, benign tumor 5 examples, pulmonary carcinoma 11 examples, gastric cancer 5 examples, intestinal cancer 5 examples, laryngocarcinoma 2 examples, hepatocarcinoma 4 examples, breast carcinoma 3 examples.
Two, the method for administration and the course of treatment:
Patient's administration anti-curing oncoma Chinese medicine composition of the present invention, each 3 grams, every day 3 times, boiled water is taken after mixing it with water, and 5 weeks were a course of treatment, and general patient serve on 6 to 12 courses of treatment.
Three, efficacy determination:
(1) doing well,improving degree: make various benign tumor volume-diminished or disappearance according to clinical observation patient administration anti-curing oncoma Chinese medicine composition of the present invention; Making cancerous cell produce regression changes; Or the cancerous cell thawing is disappeared from body, the symptom that is directed against various benign tumors, malignant tumor through clinical experiment is divided into healing, significantly effective, effective, invalid.
Cure: the patient does not have tumor or does not detect cancerous cell;
Significantly effectively: original symptom obviously alleviates more than 50%;
Effectively: original symptom obviously alleviates more than 40%;
Invalid: original sx below 10% or do not have fully alleviates.
Clinical observation result:
The patient who suffers from various benign tumors, polyp reaches 85% after the clinical symptoms improver reaches 70%, 3 month in one month after taking anti-curing oncoma Chinese medicine composition of the present invention;
After the patient who suffers from pulmonary carcinoma, gastric cancer, breast carcinoma, intestinal cancer, laryngeal carcinoma took anti-curing oncoma Chinese medicine composition of the present invention, total effective rate was more than 80% when reaching 70%, 12 month when the clinical symptoms improver is 60%, 6 month in one month.Taking the result of medicine after 6 months is listed in the table below.
6 months patient's clinical symptoms of showing to take medicine are improved situation
| Disease | The example number | Cure | Produce effects | Effectively | Invalid | Total effective rate (%) |
| Various benign tumors | 10 | 4 | 3 | 2 | 1 | 83％ |
| Pulmonary carcinoma | 11 | 2 | 4 | 4 | 1 | 80％ |
| Gastric cancer | 3 | 1 | 2 | 75％ | ||
| Breast carcinoma | 3 | 3 | 80％ | |||
| Intestinal cancer | 4 | 3 | 1 | 70％ |
Enumerate several actual cases below.
Case 1
Lee * *, man, 58 years old age, Tonghua, Jilin Province people from city.In May, 2007, the patient got a cancer of the stomach late period, implements resection operation through Tonghua City hospital, the health check-up respectively of province tumour hospital, and the operation back is with pit of the stomach pain; Diet is depressed, anorexia, nausea and vomiting, constipation; Symptoms such as dysphagia, the patient is according to each 3 grams, and every day 3 times, boiled water is taken after mixing it with water; 5 weeks were a course of treatment, took anti-curing oncoma Chinese medicine composition of the present invention, and above-mentioned symptom disappears basically after 6 months; Normal through examination in hospital each item index, existing patient can participate in Activities and physical work, no abnormal phenomenon.
Case 2
High * *, man, 38 years old, Tonghua, Jilin Province people from city.In June, 2007 patient in the Changchun, Jilin Province tumour hospital inspection suffer from advanced lung cancer, then begin to take anti-curing oncoma Chinese medicine composition of the present invention, do not take any other medicine therebetween, the patient gives an oral account no abnormality seen at present, health is good.
Case 3
Ni * *, man, 81 years old age; Tonghua, Jilin Province people from city is benign tumor through the Tonghua City examination in hospital in mid-April, 2007; But do not get rid of cancer of late stage, volume is 4.2 centimeters, and focus length is between patient's trachea door and hilus pulumonis; Dyspnea, patient is in comatose state, does not do any operation and takes the other treatment scheme.Agree that through family members took anti-curing oncoma Chinese medicine composition of the present invention 6 months, tumor all disappears, can participate in manual labor through following up a case by regular visits to the patient that health each item index is normal at present.Period in a medicine is not obeyed the other drug treatment.
Case 4
The Yan * *, woman, 51 years old age, Tonghua, Jilin Province people from city.Breast tumor is found in July, 2006 school's health check-up; Be diagnosed as breast carcinoma late period through Jilin Province tumour hospital of Tonghua City hospital, perform the operation in province tumour hospital simultaneously, begin to have taken anti-curing oncoma Chinese medicine composition of the present invention in January, 2007; Do not find transfer phenomena up to the end of the year 2007 in tumour hospital's verification; Lump is eliminated fully, and sleep takes a turn for the better, and the mental status is good.Recovery from illness is thought in province tumour hospital check.Existing patient can participate in Activities and work.
Adopt conventional method to carry out the animal toxicology test of anti-curing oncoma Chinese medicine composition of the present invention, the result shows:
1, acute toxicity test: the dose by clinical permission gives mouse stomach, and mice is movable normal;
2, long term toxicity test: by the Cmax administration of clinical permission, activities in rats and each item testing result are no abnormal.
Claims (6)
1. the Chinese medicine composition of an anti-curing oncoma, it is made up of effective ingredient or effective ingredient and pharmaceutically acceptable carrier, it is characterized in that said effective ingredient processed by following raw materials according:
The total side 29-37 of nourshing blood and promoting blood circulation weight portion; The total side 26-32 of anti-inflammatory analgetic weight portion;
Removing mass total side 84-150 weight portion of subsiding a swelling; The total side 60-66 of removing blood stasis with potent drugs expectorant weight portion;
Scolopendra 2-4 weight portion; Concha Arcae 17-23 weight portion;
Scorpio 2-6 weight portion; The mountain is aunt 10-14 weight portion now;
Periostracum Serpentis 2-6 weight portion; Herba Scutellariae Barbatae 17-23 weight portion;
Herba Lobeliae Chinensis 15-21 weight portion; Ophicalcitum 2-8 weight portion;
The total side of described nourshing blood and promoting blood circulation is made up of the 12-18 weight portion Radix Astragali, 9-15 weight portion Rhizoma Chuanxiong and 4-8 weight portion Flos Carthami;
The total side of described anti-inflammatory analgetic is made up of 7-11 weight Nidus Vespae, 7-11 weight Radix Sophorae Tonkinensis, 4-8 weight Semen Strychni and 3-7 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 40-50 weight portion Fructus Aurantii, 40-50 weight portion Fructus Aurantii Immaturus, 15-21 weight portion WULINGZI, 24-30 weight portion radix curcumae and 7-11 weight portion Sal Nitri;
The total side of described removing blood stasis with potent drugs expectorant is made up of 24-30 weight portion Alumen, 27-33 weight portion Herba Agrimoniae and 7-11 weight portion Resina Toxicodendri.
2. Chinese medicine composition according to claim 1 is characterized in that said effective ingredient processed by following raw materials according:
The total side 32-35 of nourshing blood and promoting blood circulation weight portion; The total side 28-30 of anti-inflammatory analgetic weight portion;
Removing mass total side 94-130 weight portion of subsiding a swelling; The total side 62-64 of removing blood stasis with potent drugs expectorant weight portion;
Scolopendra 2-4 weight portion; Concha Arcae 18-22 weight portion;
Scorpio 2-5 weight portion; The mountain is aunt 11-13 weight portion now;
Periostracum Serpentis 2-5 weight portion; Herba Scutellariae Barbatae 18-22 weight portion;
Herba Lobeliae Chinensis 16-18 weight portion; Ophicalcitum 2-6 weight portion;
The total side of described nourshing blood and promoting blood circulation is made up of the 14-16 weight portion Radix Astragali, 10-14 weight portion Rhizoma Chuanxiong and 5-8 weight portion Flos Carthami;
The total side of described anti-inflammatory analgetic is made up of 8-10 weight Nidus Vespae, 8-10 weight Radix Sophorae Tonkinensis, 5-8 weight Semen Strychni and 4-6 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 45-48 weight portion Fructus Aurantii, 42-48 weight portion Fructus Aurantii Immaturus, 16-20 weight portion WULINGZI, 26-28 weight portion radix curcumae and 8-10 weight portion Sal Nitri;
The total side of described removing blood stasis with potent drugs expectorant is made up of 26-28 weight portion Alumen, 28-32 weight portion Herba Agrimoniae and 8-10 weight portion Resina Toxicodendri.
3. Chinese medicine composition according to claim 1 is characterized in that said effective ingredient processed by following raw materials according:
The total side of nourshing blood and promoting blood circulation 33 weight portions; The total side of anti-inflammatory analgetic 29 weight portions;
The total side of removing mass detumescence 114 weight portions; The total side of removing blood stasis with potent drugs expectorant 63 weight portions;
Scolopendra 3 weight portions; Concha Arcae 20 weight portions;
Scorpio 4 weight portions; The mountain is aunt's 12 weight portions now;
Periostracum Serpentis 4 weight portions; Herba Scutellariae Barbatae 20 weight portions;
Herba Lobeliae Chinensis 18 weight portions; Ophicalcitum 6 weight portions;
The total side of described nourshing blood and promoting blood circulation is made up of the 15 weight portion Radixs Astragali, 12 weight portion Rhizoma Chuanxiongs and 6 weight portion Flos Carthamis;
The total side of described anti-inflammatory analgetic is made up of 9 weight Nidus Vespaes, 9 weight Radix Sophorae Tonkinensiss, 6 weight Semen Strychni and 5 weight LIAOJIANGSHI;
The total side of described removing mass detumescence is made up of 45 weight portion Fructus Aurantiis, 45 weight portion Fructus Aurantii Immaturuss, 18 weight portion WULINGZI, 27 weight portion radix curcumaes and 9 weight portion Sal Nitris;
The total side of described removing blood stasis with potent drugs expectorant is made up of 27 weight portion Alumen, 30 weight portion Herba Agrimoniaes and 9 weight portion Resina Toxicodendri.
4. Chinese medicine composition according to claim 1 is characterized in that it is granule, capsule, tablet, pill or oral liquid.
5. according to the method for preparing of the said Chinese medicine composition of each claim among the claim 1-4, it is characterized in that this method comprises the steps:
The Chinese medicine composition of A, anti-curing oncoma according to claim 1, its raw material wash, dry, are crushed to 100 purpose fine powders respectively;
B, according to the raw material consumption of the Chinese medicine composition of the described anti-curing oncoma of claim 1, take by weighing in steps A) each raw material fine powder of obtaining is as active component;
C, with above-mentioned active component with processing various dosage forms pharmaceutically can accepting carrier.
6. method according to claim 5 is characterized in that this method is included in steps A) the raw materials of traditional Chinese medicinal materials powder that obtains temperature 115-120 ℃ with pressure 0.2-0.3MPa condition under sterilization 30-35 minute.
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| CN102614284B (en) * | 2012-04-02 | 2013-08-14 | 郑美芳 | Oral liquid for treating malignancy and preparing method |
| CN103071116B (en) * | 2013-01-17 | 2014-06-04 | 张玉霞 | Traditional Chinese medicine preparation for treating esophagus cancer and preparation method thereof |
| CN104027447B (en) * | 2014-07-07 | 2016-04-06 | 杨万泉 | A kind of Chinese medicine of Therapeutic cancer |
| CN104258046A (en) * | 2014-09-30 | 2015-01-07 | 李澍 | Traditional Chinese medicine composition for treating non-small cell lung cancer with matching of TP scheme and preparation process of traditional Chinese medicine composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1228310A (en) * | 1998-03-09 | 1999-09-15 | 张富永 | Xiaoaisan powder for curing cancer |
| CN1470260A (en) * | 2002-07-26 | 2004-01-28 | 杨天权 | Tumor-diminishing pills |
| CN1857596A (en) * | 2006-03-31 | 2006-11-08 | 闵凡义 | Cancer treating medicine composition and its preparing method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1228310A (en) * | 1998-03-09 | 1999-09-15 | 张富永 | Xiaoaisan powder for curing cancer |
| CN1470260A (en) * | 2002-07-26 | 2004-01-28 | 杨天权 | Tumor-diminishing pills |
| CN1857596A (en) * | 2006-03-31 | 2006-11-08 | 闵凡义 | Cancer treating medicine composition and its preparing method |
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