CN1853688A - 一种治疗心脑血管病、缺血性中风的中药制剂及其制备方法 - Google Patents
一种治疗心脑血管病、缺血性中风的中药制剂及其制备方法 Download PDFInfo
- Publication number
- CN1853688A CN1853688A CN 200510066419 CN200510066419A CN1853688A CN 1853688 A CN1853688 A CN 1853688A CN 200510066419 CN200510066419 CN 200510066419 CN 200510066419 A CN200510066419 A CN 200510066419A CN 1853688 A CN1853688 A CN 1853688A
- Authority
- CN
- China
- Prior art keywords
- filtrate
- ethanol
- preparation
- radix astragali
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Description
实验号 | 黄芪总皂苷浓度(mg/ml) | 芍药苷浓度(mg/ml) | 栀子苷浓度(mg/ml) | 例数 | 血小板最大聚集率(%) | 聚集抑制率(%) |
对照组12345 | -1(2.11)2(1.65)3(1.19)4(0.72)5(0.26) | -2(5.51)5(1.53)1(6.83)4(2.59)3(4.18) | -4(3.46)2(8.69)1(11.31)5(0.84)3(6.08) | 644444 | 55.32±6.7119.25±3.80**20.58±2.17**18.43±1.72**30.35±0.9**29.88±1.6** | -65.2062.8066.7045.1046.00 |
实验号 | 黄芪总皂苷剂 | 芍药苷剂量 | 栀子苷剂量 | 例 | 肺栓塞时间(s) | 时间缩短率 |
量(mg/kg) | (mg/kg) | (mg/kg) | 数 | (%) | ||
对照组阿司匹林12345 | --1(0.1)2(0.2)3(0.4)4(0.8)5(1.6) | --2(2.4)5(0.3)1(4.8)4(0.6)3(1.2) | --4(1.2)2(4.8)1(9.6)5(0.6)3(2.4) | 14141414141414 | 329.36±87.36183.57±52.58**188.86±65.58**206.43±31.08**192.90±51.35**219.60±76.54**215.64±43.57** | -44.2642.6637.3241.4233.3134.53 |
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2005100664198A CN100509009C (zh) | 2005-04-25 | 2005-04-25 | 一种治疗心脑血管病、缺血性中风的中药制剂及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2005100664198A CN100509009C (zh) | 2005-04-25 | 2005-04-25 | 一种治疗心脑血管病、缺血性中风的中药制剂及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1853688A true CN1853688A (zh) | 2006-11-01 |
CN100509009C CN100509009C (zh) | 2009-07-08 |
Family
ID=37194340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2005100664198A Active CN100509009C (zh) | 2005-04-25 | 2005-04-25 | 一种治疗心脑血管病、缺血性中风的中药制剂及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN100509009C (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103196814A (zh) * | 2012-01-10 | 2013-07-10 | 南京神州英诺华医疗科技有限公司 | 一种改进枸橼酸抗凝血样血小板计数检测重复性的方法 |
CN104857010A (zh) * | 2015-04-22 | 2015-08-26 | 张永胜 | 一种栀子苷、黄芩苷和芍药苷的药物组合物 |
CN108567920A (zh) * | 2018-06-09 | 2018-09-25 | 东莞市中医院 | 一种治疗急性缺血性中风的中药组合物 |
CN112843133A (zh) * | 2021-03-05 | 2021-05-28 | 刘树民 | 一种用于治疗脑梗死的中药组合物及制备方法 |
-
2005
- 2005-04-25 CN CNB2005100664198A patent/CN100509009C/zh active Active
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103196814A (zh) * | 2012-01-10 | 2013-07-10 | 南京神州英诺华医疗科技有限公司 | 一种改进枸橼酸抗凝血样血小板计数检测重复性的方法 |
CN104857010A (zh) * | 2015-04-22 | 2015-08-26 | 张永胜 | 一种栀子苷、黄芩苷和芍药苷的药物组合物 |
CN108567920A (zh) * | 2018-06-09 | 2018-09-25 | 东莞市中医院 | 一种治疗急性缺血性中风的中药组合物 |
CN108567920B (zh) * | 2018-06-09 | 2020-10-27 | 东莞市中医院 | 一种治疗急性缺血性中风的中药组合物 |
CN112843133A (zh) * | 2021-03-05 | 2021-05-28 | 刘树民 | 一种用于治疗脑梗死的中药组合物及制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN100509009C (zh) | 2009-07-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1824177A (zh) | 一种治疗高血压的药物组合物及其制备方法和用途 | |
CN1824211A (zh) | 清金止嗽化痰制剂及新的制备方法 | |
CN1775261A (zh) | 明目地黄制剂及新的制备方法 | |
CN1853688A (zh) | 一种治疗心脑血管病、缺血性中风的中药制剂及其制备方法 | |
CN100509010C (zh) | 一种治疗心脑血管病的中药制剂及其制备方法 | |
CN1733081A (zh) | 一种具有养血安神的中药制剂及其制备方法 | |
CN1895462A (zh) | 一种治疗前列腺炎的男康软胶囊 | |
CN1679697A (zh) | 一种含有三七、瓜蒌皮、水蛭的治疗心血管疾病的中药制剂及其制备方法 | |
CN1686469A (zh) | 一种治疗冠心病的药物制剂及其制备方法 | |
CN1742871A (zh) | 藤黄健骨制剂及新的制备方法 | |
CN1895367A (zh) | 一种治疗冠心病心绞痛的中药制剂及其制备方法 | |
CN100371002C (zh) | 一种治疗心脑血管疾病的中药制剂及其制备方法 | |
CN101032534A (zh) | 救必应总皂苷的制备方法及应用 | |
CN1679700A (zh) | 一种由三七、葛根制成的治疗心脑血管疾病的药物制剂及其制备方法 | |
CN1824109A (zh) | 辽源七厘制剂及新的制备方法 | |
CN1220510C (zh) | 一种益气补血养心安神的中成药及其制备方法质量控制方法 | |
CN1291727C (zh) | 一种治疗心脑血管疾病的中药组合物及其制备方法和用途 | |
CN1634407A (zh) | 一种治疗胆囊炎的中药制剂 | |
CN1839931A (zh) | 一种治疗心脑血管疾病的药物组合物及其制备方法 | |
CN1939390A (zh) | 一种药物组合物及其制备方法 | |
CN1824013A (zh) | 四物益母制剂及新的制备方法 | |
CN1634241A (zh) | 治疗心脑血管疾病的复方三七制剂及其制备方法 | |
CN1301127C (zh) | 一种制备脉络宁注射制剂的工艺方法 | |
CN1768775A (zh) | 含有草木犀成分的组方及其制剂 | |
CN1919235A (zh) | 治疗心脑血管疾病的药物组合物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: YUNNAN PROV BIOLOGY VALLY ERIGERON FLOWER MEDICIN Free format text: FORMER OWNER: TIANLI ZHENGYUAN MEDICINE TECHNOLOGY DEVELOPMENT CO., LTD., BEIJING Effective date: 20071012 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20071012 Address after: 650224 Yunnan city of Kunming province Beijiao Palace Applicant after: Yunnan Biovalley Dengzhanhua Pharmaceutical Co., Ltd. Address before: 100070, room 1, building 2, 5358 Fu Heng street, Fengtai District Science Town, Beijing, China Applicant before: Tianli Zhengyuan Medicine Technology Development Co., Ltd., Beijing |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Chinese medicinal preparation for treating heart cerebrovascular disease and ischemic apoplexia and making method thereof Effective date of registration: 20111018 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: Yunnan Biovalley Dengzhanhua Pharmaceutical Co., Ltd. Registration number: 2011990000393 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20121112 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: Yunnan Biovalley Dengzhanhua Pharmaceutical Co., Ltd. Registration number: 2011990000393 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Chinese medicinal preparation for treating heart cerebrovascular disease and ischemic apoplexia and making method thereof Effective date of registration: 20121112 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: Yunnan Biovalley Dengzhanhua Pharmaceutical Co., Ltd. Registration number: 2012990000681 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
C56 | Change in the name or address of the patentee |
Owner name: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME: YUNNAN BIOLOGICAL VALLEY BREVISCAPIN PHARMACEUTICAL CO., LTD. |
|
CP01 | Change in the name or title of a patent holder |
Address after: 650224 Yunnan city of Kunming province Beijiao Palace Patentee after: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Address before: 650224 Yunnan city of Kunming province Beijiao Palace Patentee before: Yunnan Biovalley Dengzhanhua Pharmaceutical Co., Ltd. |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20131118 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Registration number: 2012990000681 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Chinese medicinal preparation for treating heart cerebrovascular disease and ischemic apoplexia and making method thereof Effective date of registration: 20131118 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Registration number: 2013990000866 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
PM01 | Change of the registration of the contract for pledge of patent right |
Change date: 20131118 Registration number: 2012990000681 Pledgor after: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Pledgor before: Yunnan Biovalley Dengzhanhua Pharmaceutical Co., Ltd. |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20141124 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Registration number: 2013990000866 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Chinese medicinal preparation for treating heart cerebrovascular disease and ischemic apoplexia and making method thereof Effective date of registration: 20141125 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Registration number: 2014990000982 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20160308 Granted publication date: 20090708 Pledgee: CITIC Bank, Limited by Share Ltd, Kunming branch Pledgor: YUNNAN BIOVALLEY PHARMACEUTICAL CO., LTD. Registration number: 2014990000982 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model |