CN1840043A - 一种治疗抑郁症的药物组合物及其制备方法和应用 - Google Patents
一种治疗抑郁症的药物组合物及其制备方法和应用 Download PDFInfo
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Abstract
Description
组别 | 剂量(g/kg) | 例数 | 悬尾不动时间(秒) |
对照组药物组合物帕罗西汀 | 918363.3×10-3 | 1411141213 | 107.14±49.4332.18±33.75**68.07±38.55*46.17±37.44**68.54±31.26* |
组别 | 剂量(g/kg) | 例数 | 甩头次数 | 甩头潜伏期(秒) |
对照组药物组合物帕罗西汀 | -918363.3×10-3 | 1212121212 | 6.58±4.926.25±5.909.25±6.6312.00±8.7937.83±8.72** | 556.5±379.5476.1±259.0370.1±236.8373.5±191.1145.7±47.8** |
组别 | 剂量(g/kg) | 例数 | 闭眼程度 | 僵直状态评分 |
对照组药物组合物帕罗西汀 | -918363.3×10-3 | 1313141412 | 2.38±1.331.85±1.101.36±1.230.57±1.12*0.50±1.12** | 3.69±1.942.00±2.00*1.71±1.98*0.50±0.82*0.25±0.43** |
组别 | 剂量(g/kg) | 例数 | 体温下降值 | ||||||||
4h | 5h | 6h | 7h | 8h | 9h | 10h | 11h | 12h |
对昭组药物组合物 | -91836 | 13131312 | 5.6±1.84.5±1.62.9±1.7**3.1±1.9** | 6.9±1.75.0±1.5**3.4±1.6**3.3±1.4** | 7.4±2.15.8±1.6*4.3±1.7**4.5±1.6** | 8.8±1.86.6±1.7**5.2±1.9**5.6±2.1** | 8.9±2.07.2±2.0*5.8±1.6**5.4±2.6** | 9.9±1.67.1 ±1.9**6.3±1.6**5.4±2.0** | 10.0±1.46.9±2.2**6.7±2.3**5.7±2.6** | 10.4±1.67.3±2.4**6.7±2.0**5.8±2.4** | 11.0±1.97.4±2.7**7.6±1.9**6.7±2.5** |
帕罗西汀 | 3.3×10-3 | 12 | 1.3±0.5** | 1.6±0.9** | 2.2±1.0** | 2.5±0.9** | 3.4±1.0** | 3.9±1.6** | 4.6±1.7** | 4.7±2.0** | 5.4±1.8** |
Claims (6)
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CNB2006100020212A CN100379436C (zh) | 2006-01-23 | 2006-01-23 | 一种治疗抑郁症的药物组合物及其制备方法和应用 |
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CNB2006100020212A CN100379436C (zh) | 2006-01-23 | 2006-01-23 | 一种治疗抑郁症的药物组合物及其制备方法和应用 |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101194982B (zh) * | 2006-12-07 | 2010-05-19 | 首都医科大学宣武医院 | 一种抗抑郁的中药组合物及其制备方法 |
CN101204575B (zh) * | 2007-12-20 | 2010-06-02 | 董建国 | 一种治疗抑郁性神经症的中药组合物及其制备方法和应用 |
CN101670075B (zh) * | 2009-10-16 | 2011-04-27 | 蚌埠丰原涂山制药有限公司 | 一种用于治疗抑郁症的中药组合物 |
CN103212019A (zh) * | 2012-12-10 | 2013-07-24 | 宋爱民 | 治疗抑郁症的中药制剂 |
CN107224498A (zh) * | 2016-12-13 | 2017-10-03 | 华北理工大学 | 治疗抑郁症的药物 |
CN112043807A (zh) * | 2020-09-03 | 2020-12-08 | 中国人民解放军63919部队 | 一种抗抑郁中药复方 |
CN113679779A (zh) * | 2021-09-18 | 2021-11-23 | 黑龙江省济仁药业有限公司 | 一种具有抗抑郁功效的中药组合物及其制备方法和应用 |
CN116370583A (zh) * | 2021-12-24 | 2023-07-04 | 四川大学华西医院 | 一种抗抑郁症的中药组合物及其制备方法和应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1122522C (zh) * | 2001-01-12 | 2003-10-01 | 王东桥 | 一种治疗抑郁型精神病的药物 |
-
2006
- 2006-01-23 CN CNB2006100020212A patent/CN100379436C/zh not_active Expired - Fee Related
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101194982B (zh) * | 2006-12-07 | 2010-05-19 | 首都医科大学宣武医院 | 一种抗抑郁的中药组合物及其制备方法 |
CN101204575B (zh) * | 2007-12-20 | 2010-06-02 | 董建国 | 一种治疗抑郁性神经症的中药组合物及其制备方法和应用 |
CN101670075B (zh) * | 2009-10-16 | 2011-04-27 | 蚌埠丰原涂山制药有限公司 | 一种用于治疗抑郁症的中药组合物 |
CN103212019A (zh) * | 2012-12-10 | 2013-07-24 | 宋爱民 | 治疗抑郁症的中药制剂 |
CN103212019B (zh) * | 2012-12-10 | 2014-10-22 | 宋爱民 | 治疗抑郁症的中药制剂 |
CN107224498A (zh) * | 2016-12-13 | 2017-10-03 | 华北理工大学 | 治疗抑郁症的药物 |
CN112043807A (zh) * | 2020-09-03 | 2020-12-08 | 中国人民解放军63919部队 | 一种抗抑郁中药复方 |
CN112043807B (zh) * | 2020-09-03 | 2022-05-24 | 中国人民解放军63919部队 | 一种抗抑郁中药复方 |
CN113679779A (zh) * | 2021-09-18 | 2021-11-23 | 黑龙江省济仁药业有限公司 | 一种具有抗抑郁功效的中药组合物及其制备方法和应用 |
CN116370583A (zh) * | 2021-12-24 | 2023-07-04 | 四川大学华西医院 | 一种抗抑郁症的中药组合物及其制备方法和应用 |
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