CN1829569A - 具有不通气通道的样品处理装置 - Google Patents
具有不通气通道的样品处理装置 Download PDFInfo
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- CN1829569A CN1829569A CNA2004800219884A CN200480021988A CN1829569A CN 1829569 A CN1829569 A CN 1829569A CN A2004800219884 A CNA2004800219884 A CN A2004800219884A CN 200480021988 A CN200480021988 A CN 200480021988A CN 1829569 A CN1829569 A CN 1829569A
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- substrate
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- unvented channel
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0642—Filling fluids into wells by specific techniques
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
- B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
- B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
蛋白质(4毫克/毫升) | pI | Mw(kD) |
细胞色素C | 9.6 | 12.3 |
肌红蛋白 | 7.3 | 16.9 |
人血清白蛋白 | 5.9 | 66.7 |
藻青蛋白 | 4.9 | 18.1 |
泳道号 | 级份号 | pH | 容积(微升) |
1 | 1微克藻青蛋白 | ------ | --------- |
2 | 1 | 3.8 | 1000 |
3 | 2 | 4.3 | 600 |
4 | 3 | 4.7 | 500 |
5 | 4 | 5.0 | 600 |
6 | 5 | 5.3 | 400 |
7 | 6 | 5.1 | 500 |
8 | 7 | 5.4 | 600 |
9 | 8 | 5.9 | 500 |
10 | 9 | 6.4 | 500 |
11 | 10 | 6.7 | 500 |
12 | 标志 | ------ | ------ |
13 | 4微克肌红蛋白 | ------ | ------ |
14 | 11 | 6.9 | 500 |
15 | 12 | 7.1 | 450 |
16 | 13 | 7.4 | 450 |
17 | 14 | 7.6 | 450 |
18 | 15 | 7.8 | 450 |
19 | 16 | 8.1 | 450 |
20 | 17 | 8.5 | 650 |
21 | 18 | 9.4 | 750 |
22 | 19 | 10.1 | 1000 |
23 | 20 | 10.6 | 1000 |
24 | 标志 | ------ | ------ |
pI | 装置分离 | BioRad RotoforTM | |
藻青蛋白 | 4.9 | 1-4 | 1-4 |
人血清白蛋白 | 5.9 | 4-7 | 1-7 |
肌红蛋白 | 7.3 | 10-14 | 11-17 |
细胞色素C | 9.6 | 17-18 | 18-20 |
pI | Mw(kD) | |
细胞色素C | 9.6 | 12.3 |
肌红蛋白 | 7.36 | 16.9 |
泛素 | 6.56 | 8.5 |
人血清白蛋白 | 5.92 | 66.7 |
藻青蛋白 | 4.96 | 18.1 |
Claims (45)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/610,949 | 2003-07-01 | ||
US10/610,949 US7238269B2 (en) | 2003-07-01 | 2003-07-01 | Sample processing device with unvented channel |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1829569A true CN1829569A (zh) | 2006-09-06 |
CN100431708C CN100431708C (zh) | 2008-11-12 |
Family
ID=34062328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2004800219884A Expired - Lifetime CN100431708C (zh) | 2003-07-01 | 2004-05-18 | 具有不通气通道的样品处理装置 |
Country Status (7)
Country | Link |
---|---|
US (1) | US7238269B2 (zh) |
EP (1) | EP1644118B1 (zh) |
JP (1) | JP4499720B2 (zh) |
CN (1) | CN100431708C (zh) |
AU (1) | AU2004255537B2 (zh) |
CA (1) | CA2530851A1 (zh) |
WO (1) | WO2005005045A1 (zh) |
Cited By (7)
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CN102369443A (zh) * | 2009-03-31 | 2012-03-07 | 凸版印刷株式会社 | 试样分析芯片、采用该试样分析芯片的试样分析装置和试样分析方法、以及试样分析芯片的制造方法 |
CN103547370A (zh) * | 2011-05-18 | 2014-01-29 | 3M创新有限公司 | 用于样品处理装置上体积计量的系统和方法 |
CN105626626A (zh) * | 2014-11-27 | 2016-06-01 | 无锡市海骏液压机电设备有限公司 | 铝环冷却式液压冷却器 |
CN105697464A (zh) * | 2014-11-27 | 2016-06-22 | 无锡市海骏液压机电设备有限公司 | 铝环增压式液压油冷装置 |
CN105697465A (zh) * | 2014-11-27 | 2016-06-22 | 无锡市海骏液压机电设备有限公司 | 基于智能温度检测的增压式冷却结构 |
CN109666584A (zh) * | 2018-12-29 | 2019-04-23 | 北京工业大学 | 一种可用于进行循环肿瘤细胞分选实验的实验装置 |
CN111684275A (zh) * | 2018-02-09 | 2020-09-18 | 浜松光子学株式会社 | 试样支撑体、电离法以及质量分析方法 |
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US6919058B2 (en) * | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
US20050130177A1 (en) * | 2003-12-12 | 2005-06-16 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7322254B2 (en) | 2003-12-12 | 2008-01-29 | 3M Innovative Properties Company | Variable valve apparatus and methods |
GB0401045D0 (en) * | 2004-01-17 | 2004-02-18 | Univ Sheffield | Fluid-contactor |
JP4520166B2 (ja) * | 2004-02-02 | 2010-08-04 | 独立行政法人農業・食品産業技術総合研究機構 | 樹脂製マイクロチャネル基板及びその製造方法 |
EP1856405A4 (en) * | 2005-03-09 | 2010-08-04 | Univ California | MICROFLUIDIC VALVE FOR LIQUIDS |
US7709249B2 (en) * | 2005-04-01 | 2010-05-04 | 3M Innovative Properties Company | Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector |
US7507575B2 (en) * | 2005-04-01 | 2009-03-24 | 3M Innovative Properties Company | Multiplex fluorescence detection device having removable optical modules |
US7754474B2 (en) | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
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Also Published As
Publication number | Publication date |
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JP4499720B2 (ja) | 2010-07-07 |
EP1644118B1 (en) | 2013-11-06 |
CN100431708C (zh) | 2008-11-12 |
CA2530851A1 (en) | 2005-01-20 |
EP1644118A1 (en) | 2006-04-12 |
AU2004255537A1 (en) | 2005-01-20 |
JP2007527517A (ja) | 2007-09-27 |
WO2005005045A1 (en) | 2005-01-20 |
US20050199500A1 (en) | 2005-09-15 |
US7238269B2 (en) | 2007-07-03 |
AU2004255537B2 (en) | 2010-05-20 |
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