CN1824097A - Chinese medicinal preparation for treating cough and its preparation method - Google Patents

Chinese medicinal preparation for treating cough and its preparation method Download PDF

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Publication number
CN1824097A
CN1824097A CN 200510120581 CN200510120581A CN1824097A CN 1824097 A CN1824097 A CN 1824097A CN 200510120581 CN200510120581 CN 200510120581 CN 200510120581 A CN200510120581 A CN 200510120581A CN 1824097 A CN1824097 A CN 1824097A
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radix
parts
rhizoma
preparation
chinese medicine
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包国庆
黄河
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GUIXI PHARMACEUTICAL Manufacturing Co Ltd GUANGXI
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GUIXI PHARMACEUTICAL Manufacturing Co Ltd GUANGXI
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Abstract

A Chinese medicine in the form of particles for treating the cold caused cough, fever, headache, sore of limbs, etc is prepared from 15 Chinese-medicinal materials including ephedra, perilla leaf, schizonepeta, ledebouriella root, etc through extracting, concentrating, mixing it with dextrin and cane sugar, adding alcohol, granulating, drying, cooling, spraying volatile oil, and stirring.

Description

A kind of Chinese medicine preparation for the treatment of cough and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, especially a kind of Chinese medicine preparation for the treatment of cough and preparation method thereof.
Background technology
At present the Chinese patent medicine commonly used of treatment cough clinically has a lot, and the cough in the treatment, due to the slight affection of exogenous wind-cold, inhibited pulmonary QI is coughed up phlegm, fever with aversion to cold, and it is lossless have a headache, limb aching pain, it is low voice speaking to have a stuffy nose etc., and disease is used affection of exogenous wind-cold granule, affection of exogenous wind-cold ball etc. always.Said medicine differs from one another, and certain effect is all arranged.
Summary of the invention
The purpose of this invention is to provide and a kind ofly be made into a kind of granule after ten five tastes Chinese herbal medicine extracting such as Herba Ephedrae, Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Semen Armeniacae Amarum, Rhizoma Cynanchi Stauntonii, Radix Platycodonis, Radix Peucedani, Poria, Radix Glycyrrhizae are gone out effective ingredient, this preparation can overcome the deficiency of other dosage form, for in, cough due to the slight affection of exogenous wind-cold, inhibited pulmonary QI, cough up phlegm, fever with aversion to cold, it is lossless to have a headache, limb aching pain, and the low voice speaking disease such as grade of having a stuffy nose has reasonable therapeutic effect.
The technical solution used in the present invention is:
Chinese medicine by following composition by weight is formed: 0.5~4 part in Herba Ephedrae, 0.5~4 part of Folium Perillae, 0.5~4 part of Herba Schizonepetae, 0.5~4 part of Rhizoma Et Radix Notopterygii, 0.5~4 part of Radix Saposhnikoviae, 0.5~4 part of Semen Armeniacae Amarum, 1~6 part of Rhizoma Cynanchi Stauntonii, 1~6 part of Radix Platycodonis, 1~6 part of Radix Peucedani, 0.5~4 part of Fructus Aurantii, 0.2~2 part of Radix Scutellariae, 0.5~5 part of Rhizoma pinelliae cordatae (system), 0.5~4 part of Pericarpium Citri Reticulatae, 1~6 part in Poria, 0.5~4 part in Radix Glycyrrhizae.
Best prescription is: 1 part in Herba Ephedrae, 1.67 parts of Folium Perillaes, 1.67 parts of Herba Schizonepetae, 1.67 parts of Rhizoma Et Radix Notopterygiis, 1.67 parts of Radix Saposhnikoviaes, 1.67 parts of Semen Armeniacae Amarums, 3.33 parts of Rhizoma Cynanchi Stauntoniis, 3.33 parts of Radix Platycodoniss, 3.33 parts of Radix Peucedanis, 1.67 parts of Fructus Aurantiis, 0.67 part of Radix Scutellariae, 2 parts of Rhizoma pinelliae cordatae (system), 1.67 parts of Pericarpium Citri Reticulataes, 4 parts in Poria, 1 part in Radix Glycyrrhizae.
Preparation method is:
A, take by weighing Herba Ephedrae, Folium Perillae, Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Semen Armeniacae Amarum, Rhizoma Cynanchi Stauntonii, Radix Platycodonis, Radix Peucedani, Fructus Aurantii, Radix Scutellariae, Rhizoma pinelliae cordatae (system), Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae ten five tastes Chinese herbal medicine, standby;
B, get Folium Perillae, Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Peucedani, Pericarpium Citri Reticulatae and extract volatile oil, the aqueous solution after distillation device is in addition collected, and is standby;
Medicinal residues and all the other nine flavor medicines added water retting 1 hour, decocted secondary, add for the first time 11 times of water gagings, decocted 2 hours, and added 7 times of water gagings for the second time, decocted 1 hour, merging filtrate, filter, filtrate and the merging of above-mentioned aqueous solution are concentrated into relative density and are 1.07~1.12/80 ℃ clear paste, add ethanol and make and contain alcohol amount and reach 70%, left standstill 24 hours; Filter, it is 1.35~1.38/80 ℃ thick paste that filtrate is concentrated into relative density;
C, take by weighing 0.5~4 part of thick paste, 0.05~0.4 part in dextrin, 2~16 parts of mixings of sucrose, make wet granular with ethanol as wetting agent, drying is put coldly, and spray adds volatile oil, and mixing promptly gets product.
The present invention may be made in all dosage forms, the especially granule on the pharmaceutics.
The present invention is to be the medicine that raw material is made by advanced person's preparation method with ten five tastes Chinese herbal medicine such as Herba Ephedrae, Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Semen Armeniacae Amarum, Rhizoma Cynanchi Stauntonii, Radix Platycodonis, Radix Peucedani, Poria, Radix Glycyrrhizaes.The formation of medicine of the present invention, technology, simple, clear and definite, quality is convenient to control, and making granule can increase the crowd of being suitable for, and granule is with high content of technology, patient's taking convenience, mouthfeel is good, is difficult for the moisture absorption, good stability; This product taking convenience, rapid-action, in, cough due to the slight affection of exogenous wind-cold, inhibited pulmonary QI, cough up phlegm, fever with aversion to cold, it is lossless have a headache, limb aching pain, the low voice speaking disease such as grade of having a stuffy nose has reasonable therapeutic effect.This volumes of formulation is little, takes after mixing it with hot water, is fit to the standing medication of family.
The specific embodiment
Embodiment 1:
Get Folium Perillae 1000g, Herba Schizonepetae 1000g, Rhizoma Et Radix Notopterygii 1000g, Radix Saposhnikoviae 1000g, Radix Peucedani 2000g, Pericarpium Citri Reticulatae 1000g extract volatile oil, the aqueous solution after distillation device is in addition collected; Medicinal residues and Herba Ephedrae 1000g, Semen Armeniacae Amarum 1000g, Rhizoma Cynanchi Stauntonii 2000g, Radix Platycodonis 2000g, JUKE 1000g, Radix Scutellariae 400g, Rhizoma pinelliae cordatae (system) 1000g, nine flavors such as Poria 2000g, Radix Glycyrrhizae 1000g added water retting 1 hour, decocted secondary, add for the first time 11 times of amounts, decocted 2 hours, and added 7 times of amounts for the second time, decocted 1 hour, merging filtrate, filter, filtrate and the merging of above-mentioned aqueous solution are concentrated into relative density and are 1.07~1.12/80 ℃ clear paste, add ethanol and make and contain alcohol amount and reach 70%, left standstill 24 hours; Filter, it is 1.35~1.38/80 ℃ thick paste that filtrate is concentrated into relative density.Calculate with composition by weight: take by weighing thick paste 294g, dextrin 29g, sucrose 1177g mixing, make wet granular as wetting agent with ethanol, drying, put cold, the spray add volatile oil, mixing is made 100 bags, promptly.
Embodiment 2:
Get Folium Perillae 4000g, Herba Schizonepetae 4000g, Rhizoma Et Radix Notopterygii 4000g, Radix Saposhnikoviae 4000g, Radix Peucedani 8000g, Pericarpium Citri Reticulatae 4000g extract volatile oil, the aqueous solution after distillation device is in addition collected; Medicinal residues and all the other Herba Ephedrae 4000g, Semen Armeniacae Amarum 4000g, Rhizoma Cynanchi Stauntonii 8000g, Radix Platycodonis 8000g, JUKE 4000g, Radix Scutellariae 1600g, Rhizoma pinelliae cordatae (system) 4000g, nine flavors such as Poria 8000g, Radix Glycyrrhizae 4000g, added water retting 1 hour, decoct secondary, add for the first time 11 times of amounts, decocted 2 hours, add for the second time 7 times of amounts, decocted 1 hour, merging filtrate, filter, filtrate and the merging of above-mentioned aqueous solution are concentrated into relative density and are 1.07~1.12/80 ℃ clear paste, add ethanol and make and contain alcohol amount and reach 70%, left standstill 24 hours; Filter, it is 1.35~1.38/80 ℃ thick paste that filtrate is concentrated into relative density.Calculate with composition by weight: take by weighing thick paste 2353g, dextrin 235g, sucrose 9412g mixing, make wet granular as wetting agent with ethanol, drying, put cold, the spray add volatile oil, mixing is made 1000 bags, promptly.
The function of this product cures mainly: wind-dispelling heat-dissipating, lung qi dispersing cough-relieving, activating QI to eliminate phlegm.Be used for, the cough due to the slight affection of exogenous wind-cold, inhibited pulmonary QI, cough up phlegm, fever with aversion to cold, it is lossless have a headache, limb aching pain, the low voice speaking disease such as grade of having a stuffy nose.
Usage and dosage: boiled water is taken after mixing it with water, a 15g, 3 times on the one.

Claims (4)

1, a kind of Chinese medicine preparation for the treatment of cough is characterized in that being made up of the Chinese medicine of following composition by weight: 0.5~4 part in Herba Ephedrae, 0.5~4 part of Folium Perillae, 0.5~4 part of Herba Schizonepetae, 0.5~4 part of Rhizoma Et Radix Notopterygii, 0.5~4 part of Radix Saposhnikoviae, 0.5~4 part of Semen Armeniacae Amarum, 1~6 part of Rhizoma Cynanchi Stauntonii, 1~6 part of Radix Platycodonis, 1~6 part of Radix Peucedani, 0.5~4 part of Fructus Aurantii, 0.2~2 part of Radix Scutellariae, 0.5~5 part of Rhizoma pinelliae cordatae (system), 0.5~4 part of Pericarpium Citri Reticulatae, 1~6 part in Poria, 0.5~4 part in Radix Glycyrrhizae.
2, a kind of preparation method for the treatment of the Chinese medicine preparation of cough according to claim 1 is characterized in that:
Best prescription is: 1 part in Herba Ephedrae, 1.67 parts of Folium Perillaes, 1.67 parts of Herba Schizonepetae, 1.67 parts of Rhizoma Et Radix Notopterygiis, 1.67 parts of Radix Saposhnikoviaes, 1.67 parts of Semen Armeniacae Amarums, 3.33 parts of Rhizoma Cynanchi Stauntoniis, 3.33 parts of Radix Platycodoniss, 3.33 parts of Radix Peucedanis, 1.67 parts of Fructus Aurantiis, 0.67 part of Radix Scutellariae, 2 parts of Rhizoma pinelliae cordatae (system), 1.67 parts of Pericarpium Citri Reticulataes, 4 parts in Poria, 1 part in Radix Glycyrrhizae.
3, a kind of preparation method for the treatment of the Chinese medicine preparation of cough according to claim 1 is characterized in that:
A, take by weighing Herba Ephedrae, Folium Perillae, Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Semen Armeniacae Amarum, Rhizoma Cynanchi Stauntonii, Radix Platycodonis, Radix Peucedani, Fructus Aurantii, Radix Scutellariae, Rhizoma pinelliae cordatae (system), Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae ten five tastes Chinese herbal medicine, standby;
B, get Folium Perillae, Herba Schizonepetae, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Peucedani, Pericarpium Citri Reticulatae and extract volatile oil, the aqueous solution after distillation device is in addition collected, and is standby;
Medicinal residues and all the other nine flavor medicines added water retting 1 hour, decocted secondary, add for the first time 11 times of water gagings, decocted 2 hours, and added 7 times of water gagings for the second time, decocted 1 hour, merging filtrate, filter, filtrate and the merging of above-mentioned aqueous solution are concentrated into relative density and are 1.07~1.12/80 ℃ clear paste, add ethanol and make and contain alcohol amount and reach 70%, left standstill 24 hours; Filter, it is 1.35~1.38/80 ℃ thick paste that filtrate is concentrated into relative density;
C, take by weighing 0.5~4 part of thick paste, 0.05~0.4 part in dextrin, 2~16 parts of mixings of sucrose, make wet granular with ethanol as wetting agent, drying is put coldly, and spray adds volatile oil, and mixing promptly gets product.
4, a kind of Chinese medicine preparation for the treatment of cough according to claim 1 is characterized in that: may be made in all dosage forms, especially granule on the pharmaceutics.
CN 200510120581 2005-12-27 2005-12-27 Chinese medicinal preparation for treating cough and its preparation method Pending CN1824097A (en)

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152379B (en) * 2006-09-26 2010-04-14 来柏龄 Traditional Chinese medicine for treating cough and technique of preparing the same
CN101755975A (en) * 2010-01-25 2010-06-30 中山市新运来医药科技开发有限公司大涌分公司 Chinese herbal medicine sugar and tea drink preparation for preventing and treating cold
CN101797295A (en) * 2010-04-09 2010-08-11 马海龙 Medicinal composition for treating infantile cough and preparation method thereof
CN102188574A (en) * 2010-05-14 2011-09-21 深圳市齐旺投资有限公司 Chinese medicine composition for treating influenza A virus bronchitis and preparation method thereof
CN102670968A (en) * 2012-05-31 2012-09-19 王佳丽 Drug for treating coughs and preparation method of drug
CN102961657A (en) * 2012-09-25 2013-03-13 荣成市崖头美全口腔诊所 Chinese medicinal composition for treating cough
CN103041079A (en) * 2012-12-21 2013-04-17 恒拓集团广西圣康制药有限公司 Preparation method of sugar-free Masu anti-cough compound preparation
CN103041128A (en) * 2013-01-28 2013-04-17 张士勇 Bitter almond and perilla leaf pectoral syrup and preparation method thereof
CN105362341A (en) * 2015-12-12 2016-03-02 贵州省施秉县万富农业科技发展有限公司 Traditional Chinese medicine prescription for treating cold type cold and cough
CN105902906A (en) * 2016-04-20 2016-08-31 山东明仁福瑞达制药股份有限公司 Traditional Chinese medicine composition for treating wind-cold-type cold and cough and preparation method thereof
CN108815460A (en) * 2018-09-13 2018-11-16 昆明市中医医院 Chai Ge drink

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152379B (en) * 2006-09-26 2010-04-14 来柏龄 Traditional Chinese medicine for treating cough and technique of preparing the same
CN101755975A (en) * 2010-01-25 2010-06-30 中山市新运来医药科技开发有限公司大涌分公司 Chinese herbal medicine sugar and tea drink preparation for preventing and treating cold
CN101797295A (en) * 2010-04-09 2010-08-11 马海龙 Medicinal composition for treating infantile cough and preparation method thereof
CN101797295B (en) * 2010-04-09 2011-07-27 马海龙 Medicinal composition for treating infantile cough and preparation method thereof
CN102188574A (en) * 2010-05-14 2011-09-21 深圳市齐旺投资有限公司 Chinese medicine composition for treating influenza A virus bronchitis and preparation method thereof
CN102188574B (en) * 2010-05-14 2015-10-07 深圳市齐旺投资有限公司 One treats bronchitic Chinese medicine composition of influenza A virus and preparation method thereof
CN102670968A (en) * 2012-05-31 2012-09-19 王佳丽 Drug for treating coughs and preparation method of drug
CN102961657A (en) * 2012-09-25 2013-03-13 荣成市崖头美全口腔诊所 Chinese medicinal composition for treating cough
CN103041079B (en) * 2012-12-21 2015-03-25 恒拓集团广西圣康制药有限公司 Preparation method of sugar-free Masu anti-cough compound preparation
CN103041079A (en) * 2012-12-21 2013-04-17 恒拓集团广西圣康制药有限公司 Preparation method of sugar-free Masu anti-cough compound preparation
CN103041128A (en) * 2013-01-28 2013-04-17 张士勇 Bitter almond and perilla leaf pectoral syrup and preparation method thereof
CN103041128B (en) * 2013-01-28 2014-10-01 蚌埠市第三人民医院 Bitter almond and perilla leaf pectoral syrup and preparation method thereof
CN105362341A (en) * 2015-12-12 2016-03-02 贵州省施秉县万富农业科技发展有限公司 Traditional Chinese medicine prescription for treating cold type cold and cough
CN105902906A (en) * 2016-04-20 2016-08-31 山东明仁福瑞达制药股份有限公司 Traditional Chinese medicine composition for treating wind-cold-type cold and cough and preparation method thereof
CN108815460A (en) * 2018-09-13 2018-11-16 昆明市中医医院 Chai Ge drink
CN108815460B (en) * 2018-09-13 2021-06-01 昆明市中医医院 Chai Ge Yin (decoction of firewood and kudzu vine)

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