CN1814583A - 一种制备2-对辛基苯乙基-2-氨基丙二醇盐酸盐的方法 - Google Patents
一种制备2-对辛基苯乙基-2-氨基丙二醇盐酸盐的方法 Download PDFInfo
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- CN1814583A CN1814583A CN 200610038647 CN200610038647A CN1814583A CN 1814583 A CN1814583 A CN 1814583A CN 200610038647 CN200610038647 CN 200610038647 CN 200610038647 A CN200610038647 A CN 200610038647A CN 1814583 A CN1814583 A CN 1814583A
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CNB2006100386479A CN100548968C (zh) | 2006-03-01 | 2006-03-01 | 一种制备2-对辛基苯乙基-2-氨基丙二醇盐酸盐的方法 |
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CNB2006100386479A CN100548968C (zh) | 2006-03-01 | 2006-03-01 | 一种制备2-对辛基苯乙基-2-氨基丙二醇盐酸盐的方法 |
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CN1814583A true CN1814583A (zh) | 2006-08-09 |
CN100548968C CN100548968C (zh) | 2009-10-14 |
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CNB2006100386479A Expired - Fee Related CN100548968C (zh) | 2006-03-01 | 2006-03-01 | 一种制备2-对辛基苯乙基-2-氨基丙二醇盐酸盐的方法 |
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102120720A (zh) * | 2011-01-25 | 2011-07-13 | 上海华升生物科技有限公司 | 盐酸芬戈莫德的合成新方法 |
WO2011009634A3 (en) * | 2009-07-24 | 2011-11-10 | Ratiopharm Gmbh | Process for producing fingolimod salts |
CN102432522A (zh) * | 2011-11-01 | 2012-05-02 | 中国人民解放军第二军医大学 | 一种取代吲哚-2-酮化合物的制备方法 |
WO2012070059A1 (en) * | 2010-11-25 | 2012-05-31 | Shilpa Medicare Limited | Fingolimod polymorphs and their processes |
CN102850319A (zh) * | 2011-06-27 | 2013-01-02 | 中国药科大学 | 一种制备{5-[2-(4-正辛基苯基)乙基]-2,2-二甲基-1,3-二氧六环-5-基}氨基甲酸叔丁酯的方法 |
WO2013111162A3 (en) * | 2012-01-25 | 2013-10-17 | Glenmark Generics Limited | Process for preparation of fingolimod |
WO2013185740A1 (en) | 2012-06-15 | 2013-12-19 | Zentiva, K.S. | A method for the preparation of fingolimod |
CN104788325A (zh) * | 2008-11-11 | 2015-07-22 | 诺华股份有限公司 | 芬戈莫德的结晶形式 |
US9216943B2 (en) | 2011-04-29 | 2015-12-22 | Dr. Reddy's Laboratories Ltd. | Preparation of fingolimod and its salts |
EP2658840B1 (en) | 2010-12-28 | 2019-07-03 | Synthon BV | Process for making fingolimod hydrochloride crystals |
EP2621889B1 (en) * | 2010-10-01 | 2019-07-17 | Synthon BV | Process for making fingolimod hydrochloride crystals |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102976989A (zh) * | 2012-11-26 | 2013-03-20 | 盛世泰科生物医药技术(苏州)有限公司 | 一种2-氨基-2-{2- [4-(3-苄氧基-苯基)-2-氯-苯基] -乙基}-丙烷-1,3 -二醇盐酸盐的合成方法 |
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2006
- 2006-03-01 CN CNB2006100386479A patent/CN100548968C/zh not_active Expired - Fee Related
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104788325A (zh) * | 2008-11-11 | 2015-07-22 | 诺华股份有限公司 | 芬戈莫德的结晶形式 |
US8766005B2 (en) | 2009-07-24 | 2014-07-01 | Ratiopharm Gmbh | Process for producing fingolimod salts |
WO2011009634A3 (en) * | 2009-07-24 | 2011-11-10 | Ratiopharm Gmbh | Process for producing fingolimod salts |
EP2621889B1 (en) * | 2010-10-01 | 2019-07-17 | Synthon BV | Process for making fingolimod hydrochloride crystals |
WO2012070059A1 (en) * | 2010-11-25 | 2012-05-31 | Shilpa Medicare Limited | Fingolimod polymorphs and their processes |
EP2658840B1 (en) | 2010-12-28 | 2019-07-03 | Synthon BV | Process for making fingolimod hydrochloride crystals |
CN102120720B (zh) * | 2011-01-25 | 2013-05-22 | 上海华升生物科技有限公司 | 盐酸芬戈莫德的合成新方法 |
WO2012100399A1 (zh) * | 2011-01-25 | 2012-08-02 | 上海华升生物科技有限公司 | 盐酸芬戈莫德的合成新方法 |
CN102120720A (zh) * | 2011-01-25 | 2011-07-13 | 上海华升生物科技有限公司 | 盐酸芬戈莫德的合成新方法 |
US9216943B2 (en) | 2011-04-29 | 2015-12-22 | Dr. Reddy's Laboratories Ltd. | Preparation of fingolimod and its salts |
CN102850319A (zh) * | 2011-06-27 | 2013-01-02 | 中国药科大学 | 一种制备{5-[2-(4-正辛基苯基)乙基]-2,2-二甲基-1,3-二氧六环-5-基}氨基甲酸叔丁酯的方法 |
CN102432522A (zh) * | 2011-11-01 | 2012-05-02 | 中国人民解放军第二军医大学 | 一种取代吲哚-2-酮化合物的制备方法 |
WO2013111162A3 (en) * | 2012-01-25 | 2013-10-17 | Glenmark Generics Limited | Process for preparation of fingolimod |
WO2013185740A1 (en) | 2012-06-15 | 2013-12-19 | Zentiva, K.S. | A method for the preparation of fingolimod |
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CN100548968C (zh) | 2009-10-14 |
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Address after: 201, room 01, building 108, East 210046, Gan Hua Street, Yao Road, Qixia District, Jiangsu, Nanjing Patentee after: Nanjing Yoko Biological Pharmaceutical Co., Ltd. Address before: 210018, C, 13 floor, Tak Kei Building, 188 Changjiang Road, Xuanwu District, Jiangsu, Nanjing Patentee before: Nanjing Acean Pharmaceutical Co.,Ltd. |
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