CN1809365A - 腺苷受体激动剂在治疗中的用途 - Google Patents
腺苷受体激动剂在治疗中的用途 Download PDFInfo
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- CN1809365A CN1809365A CNA2004800057235A CN200480005723A CN1809365A CN 1809365 A CN1809365 A CN 1809365A CN A2004800057235 A CNA2004800057235 A CN A2004800057235A CN 200480005723 A CN200480005723 A CN 200480005723A CN 1809365 A CN1809365 A CN 1809365A
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- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Immunology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0305150.5A GB0305150D0 (en) | 2003-03-07 | 2003-03-07 | Use of therapeutic compounds |
| GB0305150.5 | 2003-03-07 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010524262XA Division CN102058614A (zh) | 2003-03-07 | 2004-03-05 | 腺苷受体激动剂在治疗中的用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1809365A true CN1809365A (zh) | 2006-07-26 |
Family
ID=9954248
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2004800057235A Pending CN1809365A (zh) | 2003-03-07 | 2004-03-05 | 腺苷受体激动剂在治疗中的用途 |
| CN201010524262XA Pending CN102058614A (zh) | 2003-03-07 | 2004-03-05 | 腺苷受体激动剂在治疗中的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010524262XA Pending CN102058614A (zh) | 2003-03-07 | 2004-03-05 | 腺苷受体激动剂在治疗中的用途 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7790698B2 (enExample) |
| EP (1) | EP1603576A1 (enExample) |
| JP (2) | JP2006519824A (enExample) |
| KR (1) | KR20050115895A (enExample) |
| CN (2) | CN1809365A (enExample) |
| AU (1) | AU2004216891B2 (enExample) |
| CA (1) | CA2514848A1 (enExample) |
| GB (1) | GB0305150D0 (enExample) |
| NO (1) | NO20054475L (enExample) |
| NZ (1) | NZ541587A (enExample) |
| WO (1) | WO2004078184A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101947230A (zh) * | 2010-08-25 | 2011-01-19 | 苗志敏 | 5′-amp用于治疗痛风性关节炎的用途 |
| CN102470129A (zh) * | 2009-07-09 | 2012-05-23 | Cbt发展有限公司 | 作为药物使用的组合制剂 |
| CN103342727A (zh) * | 2013-07-01 | 2013-10-09 | 淮海工学院 | 一种2-甲氧基腺苷的合成方法 |
| CN108329372A (zh) * | 2017-01-20 | 2018-07-27 | 柴秋 | N6-(2-羟乙基)腺苷及其衍生物在制备治疗痛风药物中的应用 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0228723D0 (en) * | 2002-12-09 | 2003-01-15 | Cambridge Biotechnology Ltd | Treatment of pain |
| GB0305153D0 (en) * | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Identification of therapeutic compounds |
| GB0305150D0 (en) * | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Use of therapeutic compounds |
| CA2557285A1 (en) * | 2004-03-05 | 2005-09-15 | Cambridge Biotechnology Limited | Adenosine receptor agonists |
| PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
| JP2008519029A (ja) * | 2004-11-08 | 2008-06-05 | キャン−ファイト・バイオファーマ・リミテッド | 加速骨吸収の治療的処置 |
| AU2006204699B2 (en) * | 2005-01-13 | 2012-04-26 | Sirtris Pharmaceuticals, Inc. | Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| CA2622879C (en) * | 2005-11-30 | 2011-07-05 | Can-Fite Biopharma Ltd. | Use of a3 adenosine receptor agonist in osteoarthritis treatment |
| CA2654371A1 (en) | 2006-06-27 | 2008-01-03 | Biovitrum Ab (Publ) | Therapeutic compounds |
| NZ573308A (en) | 2006-06-27 | 2012-02-24 | Biovitrum Ab Publ | Adenosine derivatives for the treatment of pain |
| CN101479290A (zh) | 2006-06-27 | 2009-07-08 | 比奥维特罗姆上市公司 | 新的2′,3′-亚甲基缩醛腺苷前药用作腺苷受体激动剂的前药 |
| JP7025129B2 (ja) * | 2017-05-17 | 2022-02-24 | 小林製薬株式会社 | 筋痙攣治療剤 |
| US20220218712A1 (en) * | 2019-02-25 | 2022-07-14 | Saint Louis University | Treatment of alzheimer's disease |
| JPWO2022050230A1 (enExample) * | 2020-09-03 | 2022-03-10 | ||
| CN113116900B (zh) * | 2021-04-14 | 2022-07-08 | 兰州大学 | 一类核苷类似物在制备预防和/或治疗脑血管疾病药物中的应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4861498A (enExample) | 1971-12-01 | 1973-08-28 | ||
| BE792155A (fr) | 1971-12-01 | 1973-05-30 | Takeda Chemical Industries Ltd | Nouveaux derives de l'adenosine et leur procede de production |
| DE2359536C2 (de) | 1972-12-08 | 1984-08-02 | Takeda Chemical Industries, Ltd., Osaka | 2,6-Diaminonebularinderivate |
| JPS5461194A (en) | 1977-10-21 | 1979-05-17 | Takeda Chem Ind Ltd | Preparation of n22substituted 2*66diaminonebularin |
| JPS5461195A (en) | 1977-10-21 | 1979-05-17 | Takeda Chem Ind Ltd | N2-substituted phenyl-2,6-diaminonebularin |
| US4705758A (en) | 1984-06-19 | 1987-11-10 | Warner-Lambert Company | Adenosine receptor assay and kit |
| US5104859A (en) | 1985-09-24 | 1992-04-14 | Solimedco Aktiebolag | Continuous administration of adenosine to reduce pulmonary vascular resistance |
| US5231086A (en) * | 1985-09-24 | 1993-07-27 | Item Development Aktiebolag | Continuous administration adenosine to increase myocardial blood flow |
| US5677290A (en) * | 1990-05-10 | 1997-10-14 | Fukunaga; Atsuo F. | Therapeutic use of adenosine compounds as surgical anesthetics |
| US6004945A (en) | 1990-05-10 | 1999-12-21 | Fukunaga; Atsuo F. | Use of adenosine compounds to relieve pain |
| US5679650A (en) * | 1993-11-24 | 1997-10-21 | Fukunaga; Atsuo F. | Pharmaceutical compositions including mixtures of an adenosine compound and a catecholamine |
| US6180616B1 (en) | 1990-05-10 | 2001-01-30 | Atsuo F. Fukunaga | Use of purine receptor agonists to alleviate or normalize physiopathologically excited sensory nerve function |
| US5683989A (en) * | 1993-12-17 | 1997-11-04 | Novo Nordisk A/S | Treatment of ischemias by administration of 2,N6 -substituted adenosines |
| US5877180A (en) * | 1994-07-11 | 1999-03-02 | University Of Virginia Patent Foundation | Method for treating inflammatory diseases with A2a adenosine receptor agonists |
| IT1275420B (it) | 1995-06-02 | 1997-08-05 | Schering Plough S P A | Metodo per misurare l'affinita' di legame al recettore a2a dell'adenosina di componenti di interesse farmacologico mediante l'uso del ligando triziato (3h)-sch 58261 |
| CA2317093A1 (en) * | 1998-01-08 | 1999-07-15 | Joel M. Linden | A2a adenosine receptor agonists |
| US20030008841A1 (en) * | 2000-08-30 | 2003-01-09 | Rene Devos | Anti-HCV nucleoside derivatives |
| GB0305150D0 (en) * | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Use of therapeutic compounds |
| GB0305153D0 (en) | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Identification of therapeutic compounds |
| GB0305149D0 (en) * | 2003-03-07 | 2003-04-09 | Cambridge Biotechnology Ltd | Compounds for the treatment of pain |
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2003
- 2003-03-07 GB GBGB0305150.5A patent/GB0305150D0/en not_active Ceased
-
2004
- 2004-03-05 KR KR1020057016713A patent/KR20050115895A/ko not_active Ceased
- 2004-03-05 WO PCT/GB2004/000952 patent/WO2004078184A1/en not_active Ceased
- 2004-03-05 AU AU2004216891A patent/AU2004216891B2/en not_active Ceased
- 2004-03-05 NZ NZ541587A patent/NZ541587A/en unknown
- 2004-03-05 CN CNA2004800057235A patent/CN1809365A/zh active Pending
- 2004-03-05 US US10/547,454 patent/US7790698B2/en not_active Expired - Fee Related
- 2004-03-05 JP JP2006505924A patent/JP2006519824A/ja not_active Ceased
- 2004-03-05 CA CA002514848A patent/CA2514848A1/en not_active Abandoned
- 2004-03-05 CN CN201010524262XA patent/CN102058614A/zh active Pending
- 2004-03-05 EP EP04717693A patent/EP1603576A1/en not_active Withdrawn
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2005
- 2005-09-27 NO NO20054475A patent/NO20054475L/no not_active Application Discontinuation
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2010
- 2010-09-02 US US12/875,035 patent/US20110166093A1/en not_active Abandoned
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2012
- 2012-01-06 JP JP2012001451A patent/JP2012111764A/ja active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102470129A (zh) * | 2009-07-09 | 2012-05-23 | Cbt发展有限公司 | 作为药物使用的组合制剂 |
| CN101947230A (zh) * | 2010-08-25 | 2011-01-19 | 苗志敏 | 5′-amp用于治疗痛风性关节炎的用途 |
| CN103342727A (zh) * | 2013-07-01 | 2013-10-09 | 淮海工学院 | 一种2-甲氧基腺苷的合成方法 |
| CN108329372A (zh) * | 2017-01-20 | 2018-07-27 | 柴秋 | N6-(2-羟乙基)腺苷及其衍生物在制备治疗痛风药物中的应用 |
| CN108329372B (zh) * | 2017-01-20 | 2022-07-26 | 浙江省亚热带作物研究所 | N6-(2-羟乙基)腺苷及其衍生物在制备治疗痛风药物中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ541587A (en) | 2008-08-29 |
| KR20050115895A (ko) | 2005-12-08 |
| EP1603576A1 (en) | 2005-12-14 |
| WO2004078184A1 (en) | 2004-09-16 |
| GB0305150D0 (en) | 2003-04-09 |
| JP2012111764A (ja) | 2012-06-14 |
| NO20054475L (no) | 2005-09-27 |
| US20060234975A1 (en) | 2006-10-19 |
| CA2514848A1 (en) | 2004-09-16 |
| CN102058614A (zh) | 2011-05-18 |
| AU2004216891A1 (en) | 2004-09-16 |
| US20110166093A1 (en) | 2011-07-07 |
| JP2006519824A (ja) | 2006-08-31 |
| US7790698B2 (en) | 2010-09-07 |
| AU2004216891B2 (en) | 2009-06-18 |
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