CN1777671A - 新的半乳糖寡糖组合物及其制备 - Google Patents
新的半乳糖寡糖组合物及其制备 Download PDFInfo
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- CN1777671A CN1777671A CN 200480010853 CN200480010853A CN1777671A CN 1777671 A CN1777671 A CN 1777671A CN 200480010853 CN200480010853 CN 200480010853 CN 200480010853 A CN200480010853 A CN 200480010853A CN 1777671 A CN1777671 A CN 1777671A
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- Prior art keywords
- gal
- glc
- galactooligosaccharicomposition
- mixture
- composition
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Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
Abstract
Description
探针 | 序列 | 目标属 | 温度 | 参考文献 |
Bac303 | 5′-CCAATGTGGGGGACCTT-3′ | 类杆菌属 | 45℃ | Langendijk等人(1995) |
Bif164 | 5′-CATCCGGCATTACCACCC-3′ | 双歧杆菌属 | 50℃ | Manz等人(1996) |
Chis 150 | 5′-AAAGGAAGAUUAAUACCGCAUA-3′ | 溶组织梭状芽孢杆菌组 | 50℃ | Franks等人(1998) |
Lab158 | 5′-GGTATTAGCA(T/C)CTGTTTCCA-3′ | 乳杆菌/肠球菌属 | 45℃ | Harmsen等人(1999) |
V1 | V2 | V3 | |||||||
时间(天) | 1 | 10.5 | 21 | 1 | 10.5 | 21 | 1 | 10.5 | 21 |
总细菌(logno.) | 9.5 | 9.5 | 9.6 | 9.5 | 9.4 | 9.5 | 9.5 | 9.4 | 9.6 |
双歧杆菌属 | 8.0 | 7.9 | 8.3 | 8.0 | 8.0 | 8.3 | 8.0 | 8.0 | 8.2 |
乳杆菌属 | 7.2 | 7.2 | 7.1 | 7.0 | 7.0 | 7.1 | 7.0 | 7.0 | 6.9 |
类杆菌属 | 8.1 | 8.1 | 7.5 | 8.0 | 8.2 | 7.5 | 8.0 | 8.1 | 7.9 |
溶组织梭状芽孢杆菌组 | 6.8 | 6.9 | 7.1 | 6.9 | 6.8 | 7.0 | 6.9 | 6.8 | 7.0 |
V1 | V2 | V3 | |||||||
时间(天) | 1 | 10.5 | 21 | 1 | 10.5 | 21 | 1 | 10.5 | 21 |
总细菌(log no.) | 9.4 | 9.7 | 9.6 | 9.4 | 9.5 | 9.6 | 9.6 | 9.5 | 9.5 |
双歧杆菌属 | 8.1 | 8.0 | 8.9 | 8.0 | 8.0 | 8.7 | 8.2 | 8.2 | 8.4 |
乳杆菌属 | 7.4 | 7.6 | 7.6 | 7.3 | 7.3 | 7.5 | 7.4 | 7.3 | 7.3 |
类杆菌属 | 8.0 | 8.2 | 8.2 | 8.0 | 8.1 | 8.1 | 7.8 | 7.8 | 7.8 |
溶组织梭状芽孢杆菌组 | 6.9 | 7.0 | 6.8 | 6.8 | 6.8 | 6.7 | 7.0 | 7.0 | 6.9 |
营养物 | 含量 |
油 | 3.3% |
蛋白 | 19.2% |
纤维 | 2.8% |
灰 | 4.8% |
水分 | 13.8% |
维生素A | 9500i.u./kg |
维生素E,α生育酚 | 100i.u./kg |
维生素D3 | 1850i.u./kg |
硒、亚硒酸钠 | 0.30mg/kg |
赖氨酸 | 1.32% |
铜、硫酸铜 | 170mg/kg |
0时间* | 4周时间 | ||||
NBG | 1.6%GOS | 4%GOS | 菊粉 | ||
总细菌 | 8.75±0.22 | 8.97±0.24 | 8.99±0.23 | 8.97±0.28 | 8.95±0.28 |
双歧杆菌属 | 6.48±0.29 | 6.91±0.250 | 7.07±0.230 | 7.34±0.21a,o | 7.45±0.24a,b,o |
乳杆菌属 | 6.33±0.25 | 6.55±0.23 | 6.93±0.160 | 7.17±0.24a,o | 6.94±0.26a,o |
类杆菌属 | 7.27±0.23 | 7.75±0.240 | 7.84±0.270 | 7.85±0.220 | 8.04±0.180 |
溶组织梭状芽孢杆菌组 | 7.43±0.33 | 8.04±0.240 | 8.14±0.250 | 8.33±0.280 | 8.22±0.230 |
NEG | 1.6%GOS | 4%GOS | 菊粉 | |
近端结肠 | 5.71±0.16 | 5.65±0.11 | 5.49±0.14a,b,c | 5.90±0.27 |
远端结肠 | 7.16±0.04 | 7.16±0.03 | 7.16±0.04 | 7.12±0.02 |
乳酸乙酸丙酸丁酸 | 近端结肠 | 远端结肠 | ||||||
NEG | 1.6% GOS | 4% GOS | 菊粉 | NEG | 1.6%GOS | 4%GOS | 菊粉 | |
2.62±0.7341.43±6.5335.68±5.110.51±1.42 | 6.62±1.67a44.45±2.8127.52±2.87a10.57±1.56 | 4.41±0.77a,b51.85±2.68a,b,c32.99±8.3911.19±3.24 | 3.07±1.12b44.58±3.3130.63±3.6110.86±3.99 | ND31.61±5.5015.36±3.464.81±1.18 | ND30.68±2.3215.27±1.924.48±0.73 | ND33.57±2.2116.75±3.885.13±1.09 | ND38.54±3.66a,b,c17.36±2.166.11±1.42 |
总细菌双歧杆菌属乳杆菌属类杆菌属溶组织梭状芽孢杆菌组 | 近端结肠 | 远端结肠 | ||||||
NEG | 1.6% GOS | 4% GOS | 菊粉 | NEG | 1.6% GOS | 4% GOS | 菊粉 | |
8.61±0.247.13±0.256.94±0.237.57±0.218.12±0.23 | 8.68±0.227.30±0.267.17±0.267.76±0.218.08±0.25 | 8.62±0.217.87±0.26a,b,c7.38±0.24a7.65±0.338.13±0.28 | 8.67±0.257.37±0.327.19±0.247.97±0.24a8.07±0.27 | 8.83±0.287.03±0.256.60±0.347.77±0.278.05±0.41 | 8.81±0.217.05±0.266.96±0.217.88±0.248.15±0.15 | 8.80±0.227.41±0.27a7.16±0.35a7.82±0.268.29±0.19 | 8.80±0.297.58±0.32a,b7.05±0.308.04±0.328.18±0.23 |
Claims (21)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0315266.7 | 2003-06-30 | ||
GB0315266A GB0315266D0 (en) | 2003-06-30 | 2003-06-30 | Novel galactooligosaccharide composition and the preparation thereof |
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CNB2004800108538A Expired - Lifetime CN100434510C (zh) | 2003-06-30 | 2004-06-30 | 新的半乳糖寡糖组合物及其制备 |
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Cited By (8)
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CN101978856A (zh) * | 2010-11-13 | 2011-02-23 | 兰州大学 | 一种牦牛专用复合营养添加剂舔砖 |
CN102404990A (zh) * | 2009-02-24 | 2012-04-04 | 里特制药股份有限公司 | 益生素制剂和使用方法 |
CN102427818A (zh) * | 2009-04-23 | 2012-04-25 | 科拉萨多公司 | 新用途 |
CN103096724A (zh) * | 2010-08-21 | 2013-05-08 | 株式会社明治 | 乳糖成分较少的发酵乳及其制作方法 |
CN103648504A (zh) * | 2011-07-05 | 2014-03-19 | 科拉萨多公司 | 用于预防或减小发生代谢综合征的风险的低聚糖组合物 |
US9592248B2 (en) | 2009-02-24 | 2017-03-14 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
CN111372477A (zh) * | 2017-08-04 | 2020-07-03 | 雀巢产品有限公司 | 在含有gos的培养基中预调理的益生菌及其用途 |
CN112638181A (zh) * | 2018-09-06 | 2021-04-09 | 菲仕兰坎皮纳荷兰公司 | 双歧杆菌低变应原GOS组合物及涉及来自德氏乳酸杆菌保加利亚亚种菌株的β-半乳糖苷酶的其提供方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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AU6206801A (en) * | 2000-05-26 | 2001-12-03 | Arla Foods Amba | A new enzyme isolated from a bifidobacterium |
-
2003
- 2003-06-30 GB GB0315266A patent/GB0315266D0/en not_active Ceased
-
2004
- 2004-06-30 CN CN2008101666090A patent/CN101372679B/zh not_active Expired - Lifetime
- 2004-06-30 CN CNB2004800108538A patent/CN100434510C/zh not_active Expired - Lifetime
- 2004-06-30 UA UAA200509079A patent/UA83027C2/uk unknown
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2005
- 2005-09-19 ZA ZA200507550A patent/ZA200507550B/en unknown
Cited By (15)
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CN107320480A (zh) * | 2009-02-24 | 2017-11-07 | 里特制药股份有限公司 | 益生素制剂和使用方法 |
CN102404990A (zh) * | 2009-02-24 | 2012-04-04 | 里特制药股份有限公司 | 益生素制剂和使用方法 |
US9579340B2 (en) | 2009-02-24 | 2017-02-28 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
US9592248B2 (en) | 2009-02-24 | 2017-03-14 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
US9775860B2 (en) | 2009-02-24 | 2017-10-03 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
CN102427818A (zh) * | 2009-04-23 | 2012-04-25 | 科拉萨多公司 | 新用途 |
CN103096724A (zh) * | 2010-08-21 | 2013-05-08 | 株式会社明治 | 乳糖成分较少的发酵乳及其制作方法 |
CN101978856B (zh) * | 2010-11-13 | 2013-04-17 | 兰州大学 | 一种牦牛专用复合营养添加剂舔砖 |
CN101978856A (zh) * | 2010-11-13 | 2011-02-23 | 兰州大学 | 一种牦牛专用复合营养添加剂舔砖 |
CN103648504A (zh) * | 2011-07-05 | 2014-03-19 | 科拉萨多公司 | 用于预防或减小发生代谢综合征的风险的低聚糖组合物 |
CN107744522A (zh) * | 2011-07-05 | 2018-03-02 | 科拉萨多公司 | 用于预防或减小发生代谢综合征的风险的低聚糖组合物 |
CN111372477A (zh) * | 2017-08-04 | 2020-07-03 | 雀巢产品有限公司 | 在含有gos的培养基中预调理的益生菌及其用途 |
US11779614B2 (en) | 2017-08-04 | 2023-10-10 | Societe Des Produits Nestle S.A. | Probiotic bacteria preconditioned in a GOS-containing medium and use thereof |
CN111372477B (zh) * | 2017-08-04 | 2024-05-24 | 雀巢产品有限公司 | 在含有gos的培养基中预调理的益生菌及其用途 |
CN112638181A (zh) * | 2018-09-06 | 2021-04-09 | 菲仕兰坎皮纳荷兰公司 | 双歧杆菌低变应原GOS组合物及涉及来自德氏乳酸杆菌保加利亚亚种菌株的β-半乳糖苷酶的其提供方法 |
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Publication number | Publication date |
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CN101372679B (zh) | 2012-09-05 |
CN100434510C (zh) | 2008-11-19 |
CN101372679A (zh) | 2009-02-25 |
UA83027C2 (uk) | 2008-06-10 |
ZA200507550B (en) | 2006-06-28 |
GB0315266D0 (en) | 2003-08-06 |
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