CN1768868A - Anaesthesia possessing lubricant for alimentary tract and respiratory tract endoscope - Google Patents
Anaesthesia possessing lubricant for alimentary tract and respiratory tract endoscope Download PDFInfo
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- CN1768868A CN1768868A CN 200510094873 CN200510094873A CN1768868A CN 1768868 A CN1768868 A CN 1768868A CN 200510094873 CN200510094873 CN 200510094873 CN 200510094873 A CN200510094873 A CN 200510094873A CN 1768868 A CN1768868 A CN 1768868A
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- tract endoscope
- lubricant
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- paralytic
- respiratory tract
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Abstract
The invention relates to a lubricant with paresis used in enteron endoscope and respiratory tract endoscope. Components of said lubricant for realizing paresis comprises: phosphate methylmorphine and levogyration tetrahydropalmatine; the components of said lubricant for realizing lubricate effect comprises: disilyloxy, methyl ethylene glycol, chloromycetin in glycerin and ammonium bithiolicum glycerin; and other components of said lubricant comprises: adhesion promoter of Kapo 934, preservative agent of gluconic acid chlorhexidine and pH value adjuster of triethanolamine. And the weight proportion of said lubricant comprises: 1-10% phosphate methylmorphine, 1-10% levogyration tetrahydropalmatine, 20-50% disilyloxy, 5-35% methyl ethylene glycol, 3-30% chloromycetin in glycerin, 3-30% ammonium bithiolicum glycerin, 1-10% adhesion promoter of Kapo 934, 1-10% preservative agent of gluconic acid chlorhexidine, and 1-10% pH value adjuster of triethanolamine.
Description
Technical field
The present invention relates to paralytic lubricant that has of alimentary tract endoscope and respiratory tract endoscope use.
Background technology
The alimentary tract endoscope that uses in the hospital and the lubricant of respiratory tract endoscope all are vaseline and derivant thereof basically now, do not have paralytic, can cause bigger stimulation to patient's digestive tract and respiratory tract, feeling bad very, and some nervous patients also can produce spasm, vomiting and uncomfortable reaction such as hemorrhage, so paralytic lubricant that has that a kind of alimentary tract endoscope and respiratory tract endoscope use need be provided.
Summary of the invention:
The object of the present invention is to provide paralytic lubricant that has of a kind of alimentary tract endoscope and respiratory tract endoscope use.
Technical scheme of the present invention: the present invention is paralytic lubricant that has of a kind of alimentary tract endoscope and the use of respiratory tract endoscope, and the composition that can realize the paralytic effect with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: Codeine and rotundin; The composition that can realize lubricant effect with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: dimethyl siloxane, propylene glycol, chloromycetin in glycerin and ichthyol glycerol; Other the composition that this alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant is: viscosifier carbomer 934, antiseptic chlorhexidine gluconate and pH value regulator triethanolamine; The part by weight of the prescription of the mentioned component with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: 1% to 10% Codeine, 1% to 10% rotundin, 20% to 50% dimethyl siloxane, 5% to 35% propylene glycol, 3% to 30% chloromycetin in glycerin, 3% to 30% ichthyol glycerol, 1% to 10% viscosifier carbomer 934,1% to 10% antiseptic chlorhexidine gluconate and 1% to 10% pH value regulator triethanolamine.
Above-mentioned Codeine has the inhibitory action to respiratory center, also has the effect of calmness and antitussive, can also suppress bronchial secretion, can also suppress the contraction of bronchial smooth muscle, esophagus smooth muscle and stomach smooth muscle.
Above-mentioned rotundin has stronger antiemetic effect, also the fan is walked the central nervous system and has certain inhibitory action; At first pure water is heated to 70 ℃ to 95 ℃ standby; Then above-mentioned dimethyl siloxane, propylene glycol, chloromycetin in glycerin, ichthyol glycerol and viscosifier carbomer 934 are mixed in selected ratio, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, afterwards in 25 minutes to 30 minutes time demulcent be heated to 30 ℃ to 50 ℃ obtain A form divide standby; Then A being formed the pure water that divides with 70 ℃ to 95 ℃ mixes in selected ratio, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, afterwards in 25 minutes to 30 minutes time demulcent be heated to 50 ℃ to 70 ℃ obtain B form divide standby; Then above-mentioned Codeine and rotundin are mixed with B composition branch in selected ratio, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, afterwards in 25 minutes to 30 minutes time demulcent be heated to 30 ℃ to 50 ℃ obtain C form divide standby; Then that above-mentioned antiseptic chlorhexidine gluconate is selected ratio is formed to divide with C and is mixed, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, demulcently in 25 minutes to 30 minutes time afterwards be heated to 30 ℃ to 50 ℃ and obtain semi-finished product; At last that above-mentioned pH value regulator triethanolamine is selected ratio is mixed with semi-finished product, carry out 25 minutes to 300 minutes evenly stirring fully then in the stirred vessel of entry altitude sealing, treat temperature stabilization 30 ℃ between 40 ℃ in, can leave standstill stablize 10 minutes to 900 minutes after, treat that temperature stabilization can obtain finished product in room temperature; Can detect finished product afterwards; After detecting, can carry out quantitative filling at finished product, after the process packer is finished packing at last, promptly can be made into product.
Above-mentioned pH value regulator triethanolamine can be adjusted to the pH value with paralytic lubricant of this alimentary tract endoscope and the use of respiratory tract endoscope between 6 to 8.
The water content with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use should be lower than 35%.
The content of the heavy metal ion with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use should be lower than 0.05%.
This alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant and can be packaged as liquid agent; Or this alimentary tract endoscope and respiratory tract endoscope use have paralytic lubricant and can be packaged as aerosol.
The present invention has positive result of use: because the composition that can realize the paralytic effect with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: Codeine and rotundin; The composition that can realize lubricant effect with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: dimethyl siloxane, propylene glycol, chloromycetin in glycerin and ichthyol glycerol; Above-mentioned Codeine has the inhibitory action to respiratory center, also has the effect of calmness and antitussive, can also suppress bronchial secretion, can also suppress the contraction of bronchial smooth muscle, esophagus smooth muscle and stomach smooth muscle; Above-mentioned rotundin has stronger antiemetic effect, also the fan is walked the central nervous system and has certain inhibitory action; Because paralytic lubricant that has that this alimentary tract endoscope and respiratory tract endoscope use has paralytic, can not cause big stimulation, and some nervous patients can not produce spasm, vomiting and uncomfortable reaction such as hemorrhage yet to patient's digestive tract and respiratory tract.The present invention for safe and reliable, effect is obvious, widely used a kind of alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant.
The specific embodiment
Paralytic lubricant that has that a kind of alimentary tract endoscope of present embodiment of the present invention and respiratory tract endoscope use meets relevant technical standard; Present embodiment of the present invention is owing to the composition that can realize the paralytic effect with paralytic lubricant of this alimentary tract endoscope and the use of respiratory tract endoscope is: Codeine and rotundin; The composition that can realize lubricant effect with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: dimethyl siloxane, propylene glycol, chloromycetin in glycerin and ichthyol glycerol; Other the composition that this alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant is: viscosifier carbomer 934, antiseptic chlorhexidine gluconate and pH value regulator triethanolamine; The part by weight of the prescription of the mentioned component with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: 1% to 10% Codeine, 1% to 10% rotundin, 20% to 50% dimethyl siloxane, 5% to 35% propylene glycol, 3% to 30% chloromycetin in glycerin, 3% to 30% ichthyol glycerol, 1% to 10% viscosifier carbomer 934,1% to 10% antiseptic chlorhexidine gluconate and 1% to 10% pH value regulator triethanolamine; The part by weight of the prescription of the mentioned component with paralytic lubricant that this change road endoscope that can select in the present embodiment, and respiratory tract endoscope use is: 5.5% Codeine, 5.5% rotundin, 35% dimethyl siloxane, 15% propylene glycol, 15% chloromycetin in glycerin, 15% ichthyol glycerol, 4.5% viscosifier carbomer 934,3.5% antiseptic chlorhexidine gluconate and 2.5% pH value regulator triethanolamine; Above-mentioned Codeine has the inhibitory action to respiratory center, also has the effect of calmness and antitussive, can also suppress bronchial secretion, can also suppress the contraction of bronchial smooth muscle, esophagus smooth muscle and stomach smooth muscle; Above-mentioned rotundin has stronger antiemetic effect, also the fan is walked the central nervous system and has certain inhibitory action; At first pure water is heated to 70 ℃ to 95 ℃ standby, in the present embodiment, can select with pure water be heated to 85 ℃ standby; Then with above-mentioned dimethyl siloxane, propylene glycol, chloromycetin in glycerin, ichthyol glycerol and viscosifier carbomer 934 mix in selected ratio, carry out 25 minutes to 300 minutes evenly stirring fully then in the stirred vessel of entry altitude sealing, demulcently in 25 minutes to 30 minutes time afterwards be heated to 30 ℃ to 50 ℃ and obtain A and form to divide standby, in the present embodiment, can select and carry out 50 minutes evenly stir fully in the stirred vessel of entry altitude sealing, afterwards in 28 minutes time demulcent be heated to 37.5 ℃ obtain A form divide standby; Then A being formed the pure water that divides with 70 ℃ to 95 ℃ mixes in selected ratio, carry out 25 minutes to 300 minutes evenly stirring fully then in the stirred vessel of entry altitude sealing, demulcently in 25 minutes to 30 minutes time afterwards be heated to 50 ℃ to 70 ℃ and obtain B and form to divide standby, in the present embodiment, can select and carry out 100 minutes evenly stir fully in the stirred vessel of entry altitude sealing, afterwards in 27 minutes time demulcent be heated to 47.5 ℃ obtain B form divide standby; Then above-mentioned Codeine and rotundin are mixed with B composition branch in selected ratio, carry out 25 minutes to 300 minutes evenly stirring fully then in the stirred vessel of entry altitude sealing, demulcently in 25 minutes to 30 minutes time afterwards be heated to 30 ℃ to 50 ℃ and obtain C and form to divide standby, in the present embodiment, can select and carry out 100 minutes evenly stir fully in the stirred vessel of entry altitude sealing, afterwards in 26 minutes time demulcent be heated to 38.5 ℃ obtain C form divide standby; Then that above-mentioned antiseptic chlorhexidine gluconate is selected ratio is formed to divide with C and is mixed, carry out 25 minutes to 300 minutes evenly stirring fully then in the stirred vessel of entry altitude sealing, demulcently in 25 minutes to 30 minutes time afterwards be heated to 30 ℃ to 50 ℃ and obtain semi-finished product, in the present embodiment, can select and carry out 100 minutes evenly stir fully in the stirred vessel of entry altitude sealing, demulcently in 29 minutes time afterwards be heated to 39.5 ℃ and obtain semi-finished product; At last that above-mentioned pH value regulator triethanolamine is selected ratio is mixed with semi-finished product, carry out 25 minutes to 300 minutes evenly stirring fully then in the stirred vessel of entry altitude sealing, treat temperature stabilization 30 ℃ between 40 ℃ in, can leave standstill stablize 10 minutes to 900 minutes after, treat that temperature stabilization can obtain finished product in room temperature, in the present embodiment, can select and carry out 100 minutes evenly stir fully in the stirred vessel of entry altitude sealing, treat temperature stabilization 35 ℃ between 36 ℃ in, can leave standstill and stablize 210 minutes, treat that temperature stabilization can obtain finished product in room temperature; Can detect finished product afterwards; After detecting, can carry out quantitative filling at finished product, after the process packer is finished packing at last, promptly can be made into product; Above-mentioned pH value regulator triethanolamine can be adjusted to the pH value with paralytic lubricant of this alimentary tract endoscope and the use of respiratory tract endoscope between 6 to 8, in the present embodiment, this pH value regulator triethanolamine can be adjusted to 7 with the pH value with paralytic lubricant of this alimentary tract endoscope and the use of respiratory tract endoscope; The water content with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use should be lower than 35%, and in the present embodiment, the water content with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use should be 25%; The content of the heavy metal ion with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use should be lower than 0.05%; In the present embodiment, this alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant and can be packaged as liquid agent; In other embodiment, or this alimentary tract endoscope and respiratory tract endoscope use have paralytic lubricant and can be packaged as aerosol.
The present invention for safe and reliable, effect is obvious, widely used a kind of alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant.
Claims (8)
1, a kind of alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant, and it is characterized in that: the composition that can realize the paralytic effect with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: Codeine and rotundin; The composition that can realize lubricant effect with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: dimethyl siloxane, propylene glycol, chloromycetin in glycerin and ichthyol glycerol; Other the composition that this alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant is: viscosifier carbomer 934, antiseptic chlorhexidine gluconate and pH value regulator triethanolamine; The part by weight of the prescription of the mentioned component with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use is: 1% to 10% Codeine, 1% to 10% rotundin, 20% to 50% dimethyl siloxane, 5% to 35% propylene glycol, 3% to 30% chloromycetin in glycerin, 3% to 30% ichthyol glycerol, 1% to 10% viscosifier carbomer 934,1% to 10% antiseptic chlorhexidine gluconate and 1% to 10% pH value regulator triethanolamine.
2, alimentary tract endoscope according to claim 1 and respiratory tract endoscope use has paralytic lubricant, it is characterized in that: above-mentioned Codeine has the inhibitory action to respiratory center, the effect that also has calmness and antitussive, bronchial secretion can also be suppressed, the contraction of bronchial smooth muscle, esophagus smooth muscle and stomach smooth muscle can also be suppressed.
3, alimentary tract endoscope according to claim 1 and respiratory tract endoscope use has paralytic lubricant, it is characterized in that: above-mentioned rotundin has stronger antiemetic effect, also the fan is walked the central nervous system and has certain inhibitory action.
4, alimentary tract endoscope according to claim 1 and respiratory tract endoscope use has paralytic lubricant, it is characterized in that: at first pure water is heated to 70 ℃ to 95 ℃ standby; Then above-mentioned dimethyl siloxane, propylene glycol, chloromycetin in glycerin, ichthyol glycerol and viscosifier carbomer 934 are mixed in selected ratio, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, afterwards in 25 minutes to 30 minutes time demulcent be heated to 30 ℃ to 50 ℃ obtain A form divide standby; Then A being formed the pure water that divides with 70 ℃ to 95 ℃ mixes in selected ratio, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, afterwards in 25 minutes to 30 minutes time demulcent be heated to 50 ℃ to 70 ℃ obtain B form divide standby; Then above-mentioned Codeine and rotundin are mixed with B composition branch in selected ratio, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, afterwards in 25 minutes to 30 minutes time demulcent be heated to 30 ℃ to 50 ℃ obtain C form divide standby; Then that above-mentioned antiseptic chlorhexidine gluconate is selected ratio is formed to divide with C and is mixed, carry out 25 minutes to 300 minutes evenly stir fully then in the stirred vessel of entry altitude sealing, demulcently in 25 minutes to 30 minutes time afterwards be heated to 30 ℃ to 50 ℃ and obtain semi-finished product; At last that above-mentioned pH value regulator triethanolamine is selected ratio is mixed with semi-finished product, carry out 25 minutes to 300 minutes evenly stirring fully then in the stirred vessel of entry altitude sealing, treat temperature stabilization 30 ℃ between 40 ℃ in, can leave standstill stablize 10 minutes to 900 minutes after, treat that temperature stabilization can obtain finished product in room temperature; Can detect finished product afterwards; After detecting, can carry out quantitative filling at finished product, after the process packer is finished packing at last, promptly can be made into product.
5, alimentary tract endoscope according to claim 1 and respiratory tract endoscope use has paralytic lubricant, it is characterized in that: the pH value with paralytic lubricant that above-mentioned pH value regulator triethanolamine can use this alimentary tract endoscope and respiratory tract endoscope is adjusted between 6 to 8.
6, alimentary tract endoscope according to claim 1 and respiratory tract endoscope use has paralytic lubricant, and it is characterized in that: the water content with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use should be lower than 35%.
7, alimentary tract endoscope according to claim 1 and respiratory tract endoscope use has paralytic lubricant, and it is characterized in that: the content of the heavy metal ion with paralytic lubricant that this alimentary tract endoscope and respiratory tract endoscope use should be lower than 0.05%.
8, alimentary tract endoscope according to claim 1 and respiratory tract endoscope use has paralytic lubricant, it is characterized in that: this alimentary tract endoscope and respiratory tract endoscope use has paralytic lubricant and can be packaged as liquid agent; Or this alimentary tract endoscope and respiratory tract endoscope use have paralytic lubricant and can be packaged as aerosol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510094873 CN1768868A (en) | 2005-10-18 | 2005-10-18 | Anaesthesia possessing lubricant for alimentary tract and respiratory tract endoscope |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510094873 CN1768868A (en) | 2005-10-18 | 2005-10-18 | Anaesthesia possessing lubricant for alimentary tract and respiratory tract endoscope |
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| Publication Number | Publication Date |
|---|---|
| CN1768868A true CN1768868A (en) | 2006-05-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510094873 Withdrawn CN1768868A (en) | 2005-10-18 | 2005-10-18 | Anaesthesia possessing lubricant for alimentary tract and respiratory tract endoscope |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103170016A (en) * | 2013-04-19 | 2013-06-26 | 江苏迪沃生物制品有限公司 | Medical lubricant |
| CN106198670A (en) * | 2016-07-19 | 2016-12-07 | 合肥凯利光电科技有限公司 | Improve the buffer of pH value of upper digestive tract dynamic monitor detection precision |
| CN106248759A (en) * | 2016-07-19 | 2016-12-21 | 合肥凯利光电科技有限公司 | The preparation method of pH value of upper digestive tract dynamic monitor buffer |
| CN112587674A (en) * | 2020-12-28 | 2021-04-02 | 江苏瑞阳医疗科技有限公司 | Lubricating mucilage for gastroscope detection |
-
2005
- 2005-10-18 CN CN 200510094873 patent/CN1768868A/en not_active Withdrawn
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103170016A (en) * | 2013-04-19 | 2013-06-26 | 江苏迪沃生物制品有限公司 | Medical lubricant |
| CN103170016B (en) * | 2013-04-19 | 2014-03-12 | 江苏迪沃生物制品有限公司 | Medical lubricant |
| CN106198670A (en) * | 2016-07-19 | 2016-12-07 | 合肥凯利光电科技有限公司 | Improve the buffer of pH value of upper digestive tract dynamic monitor detection precision |
| CN106248759A (en) * | 2016-07-19 | 2016-12-21 | 合肥凯利光电科技有限公司 | The preparation method of pH value of upper digestive tract dynamic monitor buffer |
| CN106198670B (en) * | 2016-07-19 | 2018-08-28 | 合肥凯利光电科技有限公司 | Improve the buffer solution of pH value of upper digestive tract dynamic monitor detection precision |
| CN106248759B (en) * | 2016-07-19 | 2019-01-01 | 合肥凯利光电科技有限公司 | The preparation method of pH value of upper digestive tract dynamic monitor buffer |
| CN112587674A (en) * | 2020-12-28 | 2021-04-02 | 江苏瑞阳医疗科技有限公司 | Lubricating mucilage for gastroscope detection |
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