CN1742796A - Throat-clearing lozenge - Google Patents
Throat-clearing lozenge Download PDFInfo
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- CN1742796A CN1742796A CN 200510019537 CN200510019537A CN1742796A CN 1742796 A CN1742796 A CN 1742796A CN 200510019537 CN200510019537 CN 200510019537 CN 200510019537 A CN200510019537 A CN 200510019537A CN 1742796 A CN1742796 A CN 1742796A
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- pericarpium citri
- mentholum
- fructus chebulae
- chrysanthemi indici
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Abstract
The present invention relates to a throat-clearing lozenge. Its composition contains 1-10 portions of lonicera flower, 1-10 portions of chebule, 1-10 portions of wild chrysanthemum flower, 1-10 portions of tangerine peel and 0.01-0.5 portion of mentha camphor and/or 0.01-0.5 portion of peppermint oil.
Description
Technical field
The present invention relates to a kind of guttural tablets.
Background technology
Modern medicine confirms: antibacterial, virus and some materialization factors (as smoking, drink etc.) stimulation can make pharyngeal being inflamed, cause the hyperemia of pharyngeal mucous membrane layer, connective tissue and lymphadenosis under the mucosa, the mucous gland hypertrophy, hypersecretion, thus cause pharyngeal sense of discomfort, as dry, itch, scorching hot, hypodynia, foreign body sensation and hoarseness etc., control based on antiinflammatory, pain relieving, eliminate the phlegm, doctor trained in Western medicine generally waits with tabellae iodi gurgitis alleviates discomfort, but heals than refractory.The traditional Chinese medical science thinks that the throat illness is relevant with visceral dysfunction, wind-heat invading the lung, dysfunction of the spleen in transportation, insufficiency of stomach-QI are weak etc. all can cause, and prevents and treats available heat-clearing and toxic substances removing, activating QI to eliminate phlegm is a method, in treatment, Chinese medicine demonstrates sizable advantage, also also has very big potentiality to dig.
The consumer objects of general cleaning throat and moistening larynx product is the chronic pharyngitis patient, and these patients have symptoms such as throat is itched, twinge, dry cough more, and not too suitable with capsule, peroral tablets treatment, therapeutic effect is bad; Edible tea or other beverages regulate, prevent the throat discomfort effect also good to inside of human body, but action time is short; And confection, buccal tablet can the long time, directly act on the affected part, effect is relatively good, and confection, buccal tablet also help and carry, the advantage of instant edible, therefore, present existing moistening and cleaning throat product is in the majority with confection, buccal tablet, many experts think that confection, buccal tablet will be the main flow dosage forms of cleaning throat and moistening larynx product, can also develop more new varieties and satisfy market demand.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of buccal tablet that good cleaning throat and moistening larynx function is arranged.
The present invention solves the problems of the technologies described above with following technical scheme:
The prescription of primary raw material is (weight portion):
1～10 part of 1～10 part of Flos Chrysanthemi Indici of 1～10 part of Fructus Chebulae of Flos Lonicerae
0.01～0.5 part of 0.01～0.5 part of 1～10 part of Mentholum of Pericarpium Citri tangerinae and/or Oleum menthae
Its preparation method is:
Extracting honeysuckle, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae, roguing respectively, clean decocts with water, is condensed into thick paste; Excipient is added in the entry heating, dissolving, filters back and above-mentioned thick paste mixing, boil to moisture below 5%, stirring adjusting agent with Mentholum, Oleum menthae and taste below 95 ℃, tabletting promptly gets product.
The excipient and the weight portion thereof that add can be: 5～30 parts of white sugars, 5～30 parts of glucose syrups, 5～20 parts of hydroxyl isomaltuloses.
Adding taste adjustment agent and weight portion thereof can be: 0.004～0.5 part of edible salt, 0.02～0.2 part of citric acid, 0.02～0.2 part in glycyrrhizic acid one potassium.
With the buccal tablet that method of the present invention is produced, the cleaning throat and moistening larynx effect is remarkable, and production technology is simple, and moderate cost is beneficial to consumer and takes.
The specific embodiment
The used primary raw material of this product has:
Flos Lonicerae, be the dry flower of caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb., Flos Lonicerae Lonicera hypohlaucaMiq., Flos Lonicerae Lonicera confusa DC. or hair style Radix Ophiopogonis Lonicera dasystyla Rehd. or the flower that band is just opened, belong to the integration of edible and medicinal herbs material (defend the method prison and send out [2002] No. 51 adnexaes 1) of China's Ministry of Public Health regulation.It distinguishes the flavor of little sweet, and is cold in nature, is traditional heat-clearing and toxic substances removing articles for use, the drink of often making tea among the people, " one one of Chinese pharmacopoeia version in 2005 carry " clearing away heat-damp and promoting diuresis, treating stranguria, detumescence." Flos Lonicerae has antibiotic, antiviral, antiinflammatory action; the outer bacteriostatic experiment of oral pathology originality microbial body shows that Flos Lonicerae water extract all shows stronger bacteriostatic activity to Streptococcus mutans, radiation Bacillus adhaerens, bacteroides melanogenicus, gingivitis bacillus and half unwrapping wire haemophilus.
The Fructus Chebulae, be the dry mature fruit of Combretum Racemosum plant Fructus Chebulae Terminalia chebula Retz. or fine hair Fructus Chebulae Terminaliachebula Retz.var.tomentella Kurt., belong to the material that can be used for health food (defend the method prison and send out [2002] No. 51 adnexaes 2) of China's Ministry of Public Health regulation.Its bitter in the mouth, acid, puckery, property is flat, and " Chinese pharmacopoeia one one of version in 2000 is carried " pathogenic fire reducing sore-throat relieving.Be used for ... chronic cough is more than, the pharyngalgia hoarseness." Fructus Chebulae is since ancient times just for cough-relieving sound producing key medicine, " property of medicine opinion " carries: " tonneau body fluid ... ", " Japan hanako materia medica " carries: " expectorant, the therapeutic method to keep the adverse QI flowing downwards ", and " Bencao Tujing " carries: " controlling the phlegmatic cough discomfort in the throat "; Be loaded with Fructus Chebulae's drink in the recipes for Saving Lives, can control chronic cough language aphonia; " Xuanming Lun Fang, Clear Synopsis on Recipes " carries Fructus Chebulae Tang Zhi aphonia, agraphia person.
Flos Chrysanthemi Indici is the dry capitulum of feverfew Chrysanthemum indicum L., belongs to the material that can be used for health food (the same Fructus Chebulae of file) of China's Ministry of Public Health regulation.Its bitter in the mouth, suffering, cold nature, " Chinese pharmacopoeia one one of version in 2005 is carried " heat-clearing and toxic substances removing; ".Flos Chrysanthemi Indici has antibiotic significantly, antiinflammatory action.Flos Chrysanthemi Indici is also obtained better curative effect in the clinical practice of relieving sore-throat by clearing away heat.
Pericarpium Citri tangerinae has another name called Pericarpium Citri Reticulatae, is the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof, belongs to the integration of edible and medicinal herbs material (the same Flos Lonicerae of file) of China's Ministry of Public Health regulation.Its bitter in the mouth, suffering." Chinese pharmacopoeia one one of version in 2005 is carried " regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Be used for ... cough with copious phlegm ... ".Pericarpium Citri tangerinae just is the good medicine that eliminates the phlegm since ancient times, and " property of medicine opinion " carries: " expectorant ", " Japan hanako materia medica " " expectorant antitussive ".The modern pharmacology test shows that Pericarpium Citri tangerinae has good antibiotic, phlegm-dispelling functions.
Oleum menthae, freezing again for fresh stem and the Ye Jing vapor distillation of labiate Herba Menthae Mentha haplocalyx Briq., part is taken off the volatile oil that brain processing obtains.Special refrigerant fragrance is arranged, and flavor is just hot, the back is cool, and " Chinese pharmacopoeia one one of version in 2005 is carried " aromatic drug, remedium corrigens and carminative.Available mucosa produces refrigerant sense to alleviate discomfort and pain." Ancient Times in China cures the disease with Herba Menthae already, and is on the books in the Tang Dynasty 7th century of Christian era " a thousand pieces of gold dietetic therapy ".Compendium of Material Medica is carried: " Herba Menthae, suffering can be dispersed, and cool profit is clearly specially dispelled the heat in pathogenic wind expelling.So headache, eyes ... be key medicine." " the southern regions of the Yunnan Province book on Chinese herbal medicine " carry: " go up all wind of refresh oneself, end headache, dizzy ..." " Chinese medicine voluminous dictionary " carry: " dispelling wind, dispel the heat, ward off dirty, detoxifcation.Control affection due to external wind and heat, headache, conjunctival congestion ..." cure the disease with Herba Menthae already ancient times, on the books in the Tang Dynasty 7th century of Christian era " a thousand pieces of gold dietetic therapy ".Compendium of Material Medica is carried: " Herba Menthae, suffering can be dispersed, and cool profit is clearly specially dispelled the heat in pathogenic wind expelling.So headache, eyes ... be key medicine." " the southern regions of the Yunnan Province book on Chinese herbal medicine " carry: " go up all wind of refresh oneself, end headache, dizzy ..." " Chinese medicine voluminous dictionary " carry: " dispelling wind, dispel the heat, ward off dirty, detoxifcation.Control affection due to external wind and heat, headache, conjunctival congestion ...”
Mentholum, the crystallization that obtains through freezing method for asia peppermint oil [Mentha arvensis L.f.piperascens Malinv.exHolmes, syn.M.-Canadensis L (46%-80%)].Be fragrant dispelling wind for relieving itching medicine, be the Oleum menthae main component.Can optionally stimulate the Cold receptor of human body mucosa, produce sense of cold reflection and creeping chill, cause skin mucosa vasoconstriction (in fact skin keeps normal), and can slowly infiltrate through in the skin, the blood vessel that also causes to reflexive simultaneously deep tissue changes, adjust the function of blood vessel, and reach therapeutical effect.
In sum, buccal tablet scientific formulation of the present invention, reasonable, each raw material is moistening and cleaning throat good medicine.Flos Lonicerae, Flos Chrysanthemi Indici heat-clearing and toxic substances removing; Fructus Chebulae's smooth throat to stop cough; The Pericarpium Citri tangerinae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; Mentholum, the refrigerant pain relieving of Oleum menthae; The Six-element medicine is played the effect of pharynx-clearing throat-benefiting altogether.
This buccal tablet for clearing and moistening throat, the weight portion of its primary raw material is:
1～10 part of 1～10 part of Flos Chrysanthemi Indici of 1～10 part of Fructus Chebulae of Flos Lonicerae
0.01～0.5 part of 0.01～0.5 portion of Oleum menthae of 1～10 part of Mentholum of Pericarpium Citri tangerinae
The excipient that adds can be: 5～20 parts of white sugars 5～30, glucose syrup 5～30, hydroxyl isomaltulose.
Adding taste adjustment agent can be: edible salt 0.004～0.5,0.02～0.2 part of citric acid, 0.02～0.2 part in glycyrrhizic acid one potassium.
The preparation method of the said goods is:
Extracting honeysuckle, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae are chosen impurity such as roguing grass, earth, wash respectively, decoct with water twice, filter, and collecting decoction is concentrated into the thick paste of relative density 1.25～1.45 (60 ℃), and is standby.In jacketed pan, add entry and excipient, heating makes dissolving, is filtered in the vacuum sugar cooker, adds above-mentioned thick paste, mixing, boil to moisture 5% when following, stop heating, treat that temperature reduces to 70～95 ℃, add Mentholum, Oleum menthae and taste adjustment agent while stirring, stir, tabletting, promptly.
The investigation of product clinical efficacy
1. case choice criteria
1.1 diagnostic criteria
Symptom: even dry laryngopharynx, pain, hoarseness aphonia, or itching of the throat, the few expectorant of dry cough, dysphagia, bottleneck throat has foreign body sensation.
1.2 the standard of including in
1. meet above-mentioned diagnostic criteria person.
2. the age is 18-65 year person.
1.3 exclusion standard
1.3.1 do not meet above-mentioned tcm diagnosis standard person.
Though, have one of following situation person simultaneously 1.3.2 meet above-mentioned differential diagnosis in tcm standard:
1. the age is at under-18s, or the over-65s person.
2. pregnant and lying-in women or women breast-feeding their children.
3. be associated with serious primary disease such as cardiovascular, liver, kidney and hemopoietic system, the psychotic.
4. all standards of including in that do not meet, not medication in accordance with regulations can't be judged that curative effect or data are not congruent to affect the treatment and safety judgement person.
2. efficacy determination
(1) 1 week disappeared or basic the disappearance with interior clinical symptoms, sign with interior sx in 3 days in the clinical recovery medication.
(2) 1 week of produce effects medication is with interior sx, and 2 weeks disappeared or basic the disappearance with interior clinical symptoms, sign.
(3) effectively 2 weeks, most of sign disappeared with interior clinical symptom relief with interior sx 1 week of medication.
(4) after the invalid medication symptom have slightly alleviate or do not have alleviate, sign do not have obvious improvement.
3. medication
Get the product of embodiment 1, suck clothes, an a slice, six times on the one.
Product curative effect survey result table
| Sum | Clinic control | Produce effects | Effectively | Invalid | |
| The example number | 304 | 192 | 62 | 45 | 5 |
| Shared percent | 63.2 | 20.4 | 14.8 | 1.6 |
Embodiment 1
Prescription:
Flos Lonicerae 240g Fructus Chebulae 200g Flos Chrysanthemi Indici 200g Pericarpium Citri tangerinae 200g Mentholum 16g
Oleum menthae 2g white sugar 1300g glucose syrup 600g edible salt 0.4g
Preparation method:
Extracting honeysuckle, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae, choose impurity such as roguing grass, earth, wash respectively, decoct with water twice, add 10 times of amounts of water for the first time and decocted 1.5 hours, add 8 times of amounts of water for the second time and decocted 1 hour, filter, collecting decoction is concentrated into the thick paste of relative density 1.35～1.40 (60 ℃), and is standby.In jacketed pan, add white sugar, glucose syrup and water 800ml, heating makes dissolving, is filtered in the vacuum sugar cooker, adds above-mentioned thick paste, mixing, boil to moisture at about 4% o'clock, stop heating, treat that temperature reduces to about 90 ℃, add Mentholum, Oleum menthae, edible salt while stirring, stir tabletting, every heavy 2.0g.
Embodiment 2
Prescription:
Flos Lonicerae 400g Fructus Chebulae 150g Flos Chrysanthemi Indici 80g Pericarpium Citri tangerinae 250g Mentholum 23g
Oleum menthae 6g white sugar 300g glucose syrup 1500g edible salt 1g
Preparation method:
Flos Lonicerae, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae are handled with embodiment 1, decoct with water twice, add 8 times of amounts of water for the first time and decoct 2.5 hours, add for the second time 8 times of amounts of water and decocted 2 hours, filter collecting decoction, be concentrated into the thick paste of relative density 1.30～1.35 (60 ℃), standby.In jacketed pan, add hydroxyl isomaltulose and water 600ml, heating makes dissolving, is filtered in the vacuum sugar cooker, adds above-mentioned thick paste, mixing, boil to moisture at about 4% o'clock, stop heating, treat that temperature reduces to about 80 ℃, add Mentholum, Oleum menthae, edible salt while stirring, stir tabletting, every heavy 2.5g.
Embodiment 3
Prescription:
Flos Lonicerae 450g Fructus Chebulae 250g Flos Chrysanthemi Indici 150g Pericarpium Citri tangerinae 300g Mentholum 1g
Oleum menthae 10g white sugar 500g glucose syrup 1300g edible salt 4g
Preparation method:
Flos Lonicerae, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae are handled with embodiment 1, decoct with water twice, add 12 times of amounts of water for the first time and decoct 2 hours, add for the second time 10 times of amounts of water and decocted 1.5 hours, filter collecting decoction, be concentrated into the thick paste of relative density 1.30～1.35 (60 ℃), standby.In jacketed pan with white sugar, glucose syrup and water 850ml, heating makes dissolving, is filtered in the vacuum sugar cooker, adds above-mentioned thick paste, mixing, boil to moisture at about 3% o'clock, stop heating, treat that temperature reduces to about 85 ℃, add Mentholum, Oleum menthae, edible salt while stirring, stir tabletting, every heavy 2.2g.
Embodiment 4
Prescription:
Flos Lonicerae 500g Fructus Chebulae 400g Flos Chrysanthemi Indici 250g Pericarpium Citri tangerinae 350g Mentholum 5g
Oleum menthae 8g white sugar 800g glucose syrup 1000g edible salt 3g
Preparation method:
Flos Lonicerae, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae are handled with embodiment 1, decoct with water twice, add 11 times of amounts of water for the first time and decoct 2.5 hours, add for the second time 9 times of amounts of water and decocted 1.5 hours, filter collecting decoction, be concentrated into the thick paste of relative density 1.40～1.45 (60 ℃), standby.In jacketed pan, add white sugar, glucose syrup and water 750ml, heating makes dissolving, is filtered in the vacuum sugar cooker, adds above-mentioned thick paste, mixing, boil to moisture at about 4.5% o'clock, stop heating, treat that temperature reduces to about 70 ℃, add Mentholum, Oleum menthae, edible salt while stirring, stir tabletting, every heavy 1.8g.
Embodiment 5
Prescription:
Flos Lonicerae 100g Fructus Chebulae 450g Flos Chrysanthemi Indici 300g Pericarpium Citri tangerinae 450g Mentholum 10g
Hydroxyl isomaltulose 300g edible salt 1g citric acid 2g glycyrrhizic acid one potassium 1.5g
Preparation method:
Flos Lonicerae, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae are handled with embodiment 1, decoct with water twice, add 14 times of amounts of water for the first time and decoct 1.5 hours, add for the second time 12 times of amounts of water and decocted 1.5 hours, filter collecting decoction, be concentrated into the thick paste of relative density 1.25～1.30 (60 ℃), standby.In jacketed pan, add hydroxyl isomaltulose and water 700ml, heating makes dissolving, is filtered in the vacuum sugar cooker, adds above-mentioned thick paste, mixing, boil to moisture at about 3.5% o'clock, stop heating, treat that temperature reduces to about 75 ℃, add Mentholum, Oleum menthae, edible salt, citric acid, glycyrrhizic acid one potassium while stirring, stir tabletting, every heavy 1.5g.
Embodiment 6
Prescription:
Flos Lonicerae 80g Fructus Chebulae 200g Flos Chrysanthemi Indici 450g Pericarpium Citri tangerinae 60g
Oleum menthae 15g hydroxyl isomaltulose 900g edible salt 25g citric acid 8g glycyrrhizic acid one potassium 8g
Preparation method:
Flos Lonicerae, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae are handled with embodiment 1, decoct with water twice, add 12 times of amounts of water for the first time and decoct 2 hours, add for the second time 9 times of amounts of water and decocted 1 hour, filter collecting decoction, be concentrated into the thick paste of relative density 1.35～1.40 (60 ℃), standby.In jacketed pan, add hydroxyl isomaltulose and water 600ml, heating makes dissolving, is filtered in the vacuum sugar cooker, adds above-mentioned thick paste, mixing, boil to moisture at about 4% o'clock, stop heating, treat that temperature reduces to about 85 ℃, add Mentholum, Oleum menthae, edible salt while stirring, stir tabletting, every heavy 1g.
Claims (4)
1. guttural tablets is characterized in that the weight portion of primary raw material is:
0.01～0.5 part of 0.01～0.5 part of 1～10 part of Mentholum of 1～10 part of Pericarpium Citri tangerinae of 1～10 part of Flos Chrysanthemi Indici of 1～10 part of Fructus Chebulae of Flos Lonicerae and/or Oleum menthae.
2. a guttural tablets is characterized in that its preparation method is
The weight portion of primary raw material is:
A kind of or its mixture in 1～10 part of Mentholum of 1～10 part of Pericarpium Citri tangerinae of 1～10 part of Flos Chrysanthemi Indici of 1～10 part of Fructus Chebulae of Flos Lonicerae and/or the Oleum menthae, its weight portion are respectively 0.01～0.5 part, 0.01～0.5 part;
Preparation technology is: extracting honeysuckle, Fructus Chebulae, Flos Chrysanthemi Indici, Pericarpium Citri tangerinae, and roguing respectively, clean decocts with water, is condensed into thick paste; Excipient is added in the entry heating, dissolving, filters back and above-mentioned thick paste mixing, boil to moisture below 5%, adjust agent adding Mentholum, Oleum menthae and taste below 95 ℃, stir, tabletting promptly gets product.
3. guttural tablets as claimed in claim 2 is characterized in that the excipient that adds is a kind of or its mixture in white sugar or glucose syrup or the hydroxyl isomaltulose, and its weight portion is respectively 5～30 parts, 5～30 parts and 5～20 parts.
4. as claim 2 or 3 described guttural tablets, it is characterized in that the taste adjustment agent that adds is a kind of or its mixture in edible salt or citric acid or glycyrrhizic acid one potassium, its weight portion is respectively 0.004～0.5 part, 0.02～0.2 part and 0.02～0.2 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100195373A CN1331495C (en) | 2005-09-27 | 2005-09-27 | Throat-clearing lozenge |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100195373A CN1331495C (en) | 2005-09-27 | 2005-09-27 | Throat-clearing lozenge |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1742796A true CN1742796A (en) | 2006-03-08 |
| CN1331495C CN1331495C (en) | 2007-08-15 |
Family
ID=36138421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100195373A Expired - Fee Related CN1331495C (en) | 2005-09-27 | 2005-09-27 | Throat-clearing lozenge |
Country Status (1)
| Country | Link |
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| CN (1) | CN1331495C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101836683A (en) * | 2010-03-12 | 2010-09-22 | 广州星群（药业）股份有限公司 | Chinese-traditional-medicine-extract-containing throat-soothing candy |
| CN102512533A (en) * | 2011-12-16 | 2012-06-27 | 曲靖开发区格力康生物科技发展有限公司 | Traditional Chinese medicine composition for treating swelling and pain in throat and preparation thereof |
| CN103190556A (en) * | 2012-01-10 | 2013-07-10 | 华源利康生物技术（北京）有限公司 | Novel buccal tablet with effects of invigorating stomach, dehumidifying, clearing away the lung-heat and reducing phlegm and preparation method thereof |
| CN103749933A (en) * | 2014-02-26 | 2014-04-30 | 腾冲县元兴果品实业有限公司 | Preserved myrobalan buccal tablet and preparation method |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1144113A (en) * | 1995-01-19 | 1997-03-05 | 王时新 | Medicine for curing throat disease and its preparation method |
| CN100450504C (en) * | 2003-12-11 | 2009-01-14 | 天津天士力制药股份有限公司 | Medication for treating pharyngitis |
-
2005
- 2005-09-27 CN CNB2005100195373A patent/CN1331495C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101836683A (en) * | 2010-03-12 | 2010-09-22 | 广州星群（药业）股份有限公司 | Chinese-traditional-medicine-extract-containing throat-soothing candy |
| CN101836683B (en) * | 2010-03-12 | 2013-07-17 | 广州白云山星群(药业)股份有限公司 | Chinese-traditional-medicine-extract-containing throat-soothing candy |
| CN102512533A (en) * | 2011-12-16 | 2012-06-27 | 曲靖开发区格力康生物科技发展有限公司 | Traditional Chinese medicine composition for treating swelling and pain in throat and preparation thereof |
| CN103190556A (en) * | 2012-01-10 | 2013-07-10 | 华源利康生物技术（北京）有限公司 | Novel buccal tablet with effects of invigorating stomach, dehumidifying, clearing away the lung-heat and reducing phlegm and preparation method thereof |
| CN103749933A (en) * | 2014-02-26 | 2014-04-30 | 腾冲县元兴果品实业有限公司 | Preserved myrobalan buccal tablet and preparation method |
| CN103749933B (en) * | 2014-02-26 | 2015-05-06 | 腾冲县元兴果品实业有限公司 | Preserved myrobalan buccal tablet and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1331495C (en) | 2007-08-15 |
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Address after: 530003, 56 Garden Avenue, Nanning, the Guangxi Zhuang Autonomous Region Patentee after: GUANGXI BOKE PHARMACEUTICAL CO., LTD., GUANGXI Address before: 530003, 56 Garden Avenue, Nanning, the Guangxi Zhuang Autonomous Region Patentee before: Boke Pharmaceutical Co., Ltd., Guangxi |
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Granted publication date: 20070815 Termination date: 20200927 |
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