CN1698875A - Medicinal wine for treatment of cancer - Google Patents
Medicinal wine for treatment of cancer Download PDFInfo
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- CN1698875A CN1698875A CN 200510073277 CN200510073277A CN1698875A CN 1698875 A CN1698875 A CN 1698875A CN 200510073277 CN200510073277 CN 200510073277 CN 200510073277 A CN200510073277 A CN 200510073277A CN 1698875 A CN1698875 A CN 1698875A
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Abstract
Disclosed is a medicinal wine for treatment of cancer which is prepared from smoked plum, gorgon euryale seed, coix seed, hyacinth bean, red phaseolus bean, gen-seng, poria cocos wolf, white fungus, walnut branch, round-shaped rice, walnut kernel, radish seeds, black sesame seeds, Chinese yam, and haw, crystal sugar, mulberry, malt, Chinese dates, edible tree fungus, apricot seeds, bee honey, and high grade white spirit.
Description
A kind of medicated wine for the treatment of gastric cancer, esophageal carcinoma, hepatocarcinoma, pulmonary carcinoma, colon, rectal cancer, cancer of pancreas, carcinoma of tongue, nasopharyngeal carcinoma, thyroid carcinoma.
The present invention relates to the medicated wine of a kind of gastric cancer, esophageal carcinoma, hepatocarcinoma, pulmonary carcinoma, colon, rectal cancer, cancer of pancreas, carcinoma of tongue, nasopharyngeal carcinoma, thyroid carcinoma.In today of talking " cancer " complexion changed, many people know that cancer is that a kind of development is rapid, and almost not having has Therapeutic Method, and can seize the disease of people's life in a short time.It can occur in the many organs and the tissue of human body, and where no matter occurs in, the seemingly final final result that loses one's life, and this also is to make people talk the basic reason of " cancer " complexion changed.A kind of anticancer medicated wine, cost is low, good effect and without any side effects.
The purpose of this invention is to provide a kind of medicated wine for the treatment of gastric cancer, esophageal carcinoma, hepatocarcinoma, pulmonary carcinoma, colon, rectal cancer, cancer of pancreas, carcinoma of tongue, nasopharyngeal carcinoma, thyroid carcinoma.
The present invention adopts: 1, Fructus Mume: nature and flavor acid is flat.Return liver, spleen, lung, large intestine channel.Effect: astringe the lung, astringing intestine to stop diarrhea, promote the production of body fluid, relieving colic caused by ascaris.Be used for chronic cough of deficiency lung, the chronic diarrhea chronic dysentery, deficiency-heat is quenched one's thirst, ascarid Jue stomachache, vomiting." herbal classic is met former ": " Fructus Mume acid is received, the smart appetizing of benefit, the astringing intestine to stop diarrhea of astringing the lung, preventing or arresting vomiting arresting sweating, Dingchuan relieving colic caused by ascaris.The Imabari dysentery is more than, with the Fructus Mume charred medicinal herb with its property retained, and gradually the ending of half soup intestinal "; 2, Semen Euryales, nature and flavor are sweet, puckery flat.Return spleen, kidney channel.Effect: spleen reinforcing is dried, supplementing the kidney to control the nocturnal.Be used for diarrhea due to hypofunction of the spleen, with the passing of time more than, emission due to deficiency of the kidney, incontinence of urine, leukorrhagia.Appetizing helps gas.Compendium of Material Medica: " kidney tonifying that quenches the thirst is controlled incontinence of urine, seminal emission nebulousurine leukorrhagia "; 3, Seem Lablab Album: also claim plaque bean, delicate eyebrows bean.Seem Lablab Album can be divided into Semen Lablab Album, Dolicnops cultratus Tnunb., blue or green Seem Lablab Album and purple Seem Lablab Album.The nutritive value of Seem Lablab Album is higher, and protein content is green pepper, Fructus Lycopersici esculenti, Fructus Cucumidis sativi 1-4 a times, and Vitamin C content is higher, also is rich in the trace element zinc of needed by human, and it can promote intelligence and vision to grow, and improves the immunity of human body.It is low that Seem Lablab Album is received content, is the desirable vegetable of heart disease, hypertension, nephritis patient.The spleen reinforcing stomach function regulating that Semen Lablab Album has, the effect of the removing dampness of relieving summer heat can be treated insufficiency of the spleen singultus, the lack of appetite chronic diarrhea, and heat-damp in summer is vomited and diarrhoea, diabetes, the inferior disease of red and white leukorrhea.The composition that contains plant acid in the Seem Lablab Album can prevent cell generation canceration.Non-solubility fiber in the Seem Lablab Album can reduce the sickness rate of colon cancer; 4, Semen Coicis contains Semen Coicis oil, coixenolide, sterin, several amino acids, carbohydrate, vitamin B
1Etc. nutritional labeling.Semen Coicis has effects such as promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, and be usually used in weakness due to chronic disease and reach convalescent period after being ill, be old man, child medicinal food preferably.Diseases such as Semen Coicis can be treated and be had loose bowels, arthralgia chiefly caused by damp pathogen, edema, acute appendicitis, stranguria with turbid discharge, leucorrhea, the skin and complexion improving of also can improving looks is controlled verruca plana etc.That Semen Coicis has is analgesic, calm, analgesia, suppress the effect of Skeletal Muscle Contraction.Be commonly used to control diseases such as chronic enteritis, appendicitis, rheumatic arthralgia, urinary tract infection.Semen Coicis also has antitumaous effect, is of value to diseases such as removing rheumatism, numb hand and foot as often edible, and helps skin fitness; 5, Semen Phaseoli: have another name called Semen Ormosiae Hosiei, Zhu's Semen Phaseoli, Semen Phaseoli, Semen Phaseoli etc., mineral such as Semen Phaseoli rich in proteins, fat, carbohydrate, crude fibre, calcium, phosphorus, ferrum, copper, and contain vitamin B
1, vitamin B
2, nutritional labeling such as nicotinic acid.Semen Phaseoli has strengthening by means of tonics, strengthening the spleen and nourishing the stomach, diuresis, anti-inflammation, removes effects such as toxin.Semen Phaseoli can also appetite stimulator, promotes gastro-intestinal digestion to absorb.Semen Phaseoli has good curative effect to the edema that nephropathy, heart disease caused; 6, Radix Ginseng: sweet, the little hardship of nature and flavor, tepor.Return spleen, lung meridian.Effect: strongly invigorating primordial QI, invigorating the spleen to benefit the lung, intelligence is calmed the nerves, increased to promoting the production of body fluid to quench thirst.Being used for the deficiency of vital energy desires to take off.Deficiency of spleen-QI, lung qi loses empty, and Tianjin wound is thirsty, quenches one's thirst.Irritability, insomnia and dreamful sleep, palpitation with fear are forgetful.Radix Ginseng is the root of Araliaceae Radix Ginseng.Radix Ginseng has " Radix Panacis Quinquefolii (Radix Panacis Quinquefolii) " of " Fructus Arctii " U.S. of " Korean Ginseng " Japan of " Jilin Radix Ginseng " Korea of China in the world.Radix Ginseng contains the Radix Ginseng soap, panax acid, volatile oil, saccharide, choline several amino acids, nicotinic acid, pantothenic acid, vitamin B
1, vitamin B
2Reach compositions such as calcium, phosphorus, potassium, sodium, ferrum.The Radix Ginseng modern medicine study confirms, nervous system there is good regulating action, but stimulating central nervous system, cardiotonic is arranged, the promoting sexual gland hormone effect is arranged, the energy blood sugar lowering, the function of enhancing emiocytosis insulin, energy adrenal cortex reinforcing function, improve the body adaptive capacity of environment to external world, human body immunity improving power, Radix Ginseng can also promote proteinic ribonucleic acid synthetic, suppress the formation of hypercholesterolemia, cholesterol reducing, prevent arteriosclerosis, can be used for heart failure, diseases such as hypoimmunity, diabetes, hyperlipidemia; 7, Poria: be porous section plant, the dry sclerotia of Poria.Poria contains the β pachyman, the caproic acid pachymic acid, and pachymic acid, natural gum, chitin, protein, fat, sterin, ovum phosphorus, glucose, gland are looked sidelong at cry of certain animals, histidine, choline, β pachyman catabolic enzyme, lipase, compositions such as protein enzyme.The Poria nature and flavor are sweet, light, put down, have eliminating dampness and diuresis, the strengthening the spleen stomach function regulating, and the mind tranquilizing and the heart calming effect is applicable to cards such as treatment dysuria, edema, distension expectorant disease drink, cough with dyspnea, vomiting, diarrhoea, seminal emission, premature ejaculation, cardiopalmus, insomnia, forgetful, dreaminess.Modern medicine study, β pachyman have the effect that strengthens immune function of human body, often take to strengthen disease-resistant, the anti-cancer ability of human body; 8, Tremella: claim Tremella again, Tremella.Tremella contains abundant colloid, nutrients such as multivitamin and 17 seed amino acids and polysaccharide.Contained colloid has the nutrient substance that promotes in the food more and by the effect that body absorbed in the Tremella, also can increase the viscosity of blood, has the hemorrhage effect that prevents.Contained a kind of acidic polysaccharose class goods and materials in the Tremella, immunity that can enhancing body promotes the mobility of T cell, enhancing body effectively, the inhibition of cancerous cell and kill ability again.The contained nutritional labeling of Tremella is abundant and comprehensively, often edible lung moistening, nourishing the stomach, strong intelligence is arranged, enriches blood, effects such as kidney tonifying, beauty treatment.Tremella is that cough due to consumptive disease, sputum mixed with blood, senile chronic bronchitis, pulmonary tuberculosis, pulmonary heart disease, deficiency-heat are thirsty, the ideal rehabilitation food of patients such as cancer; 9, branch of Semen Juglandis: the stagnant dissipating blood stasis of change, cough and asthma, main blood stasis, pathogen are killed small worm.Control blood agglomeration, effects such as blood is secret, blood is dry, logical profit stool, pain relieving; 10, Semen oryzae sativae: contain the starch that human body must face, protein, fat, vitamin B
1, vitamin B
2, nutritional labeling such as hydrochloric acid, vitamin C and calcium, phosphorus, ferrum, nutrition, the heat of needed by human body can be provided.Protein in the brown rice, fat, vitamin content are all many than highed milled rice, and digestive tract disease such as gastropathy, constipation, hemorrhoid are had certain therapeutic effect.Semen oryzae sativae has strengthening the spleen and stomach, invigorating middle warmer gas, YIN nourishing and the production of body fluid promoting, and relieving restlessness is quenched the thirst, effects such as intestine-stabling and anti-diarrheal.Be used for weakness of the spleen and stomach, excessive thirst, malnutrition, disease such as weak after being ill; 11, Semen Juglandis: Semen Juglandis contains abundant fat, protein, carbohydrate, calcium, phosphorus, ferrum, manganese, zinc, potassium and vitamin A, vitamin B
1, vitamin B
2, composition such as hydrochloric acid, vitamin C, vitamin E, be the strengthening by means of tonics good merchantable brand.Semen Juglandis has tonifying the kidney to consolidate the essence, warming the lung Dingchuan, loosening bowel to relieve constipation, the function of diuresis Sal Nitri.Also can be used for lumbago due to renal deficiency, diseases such as impotence and seminal emission, early whitening of beard and hair, dizziness and tinnitus, the deficiency of the lung are breathed heavily for a long time, dryness of the intestine constipation, lithangiuria.The contained unsaturated fatty acid of Semen Juglandis and high quality protein, phosphorus etc. are the main matter of nutrition brain.Can increase memory by force, brain-strengthening, defying age, be suitable for diseases such as the dizziness, tinnitus of old body void, forgetful, insomnia especially.Semen Juglandis contains multivitamin, helps body metabolism; 12, Semen Raphani: nature and flavor suffering, sweet, flat.Return spleen, stomach, lung meridian.Effect: promoting digestion and removing stagnation, lowering the adverse-rising QI to resolve phlegm.Be used for accumulation of food in the stomach and intes tine due to indigestion, QI stagnating in middle-JIAO distension and fullness in the abdomen, belching and acid regurgitation or the stomachache disease such as smooth deeply and not of having loose bowels.Be used for the expectorant birth and stop up Sheng, asthma and cough belongs to excess syndrome person; 13, Semen Sesami Nigrum: Semen Sesami contains a large amount of fat and protein, also has saccharide, vitamin, mineral.The oil that Semen Sesami pressed claims Oleum sesami, claims Oleum Sesami again, is mainly oleic acid and linoleic glyceride, and is living ripe edible, removes sliding the rushing down of defecating, and the outer all sick Wujis of person are give off a strong fragrance in the flavoring agent a kind of.Several essential amino acids that Semen Sesami contains are at vitamin E, vitamin B
1Reciprocal action under, can quicken the human metabolism function.Ferrum that contains in the Semen Sesami and vitamin E are the prevention anemias, and activating brain cell is removed the important component of blood vessel deposit.Semen Sesami has the effect of invigorating the liver and kidney, moistening five ZANG-organs, can be used for treating dizzy due to the Liver and kidney asthenia of essence and blood, and early whitening of beard and hair, is walked with difficulty diseases such as deficient five internal organs dryness of the intestine constipation at alopecia, soreness of the waist and knees.In the contained fat of Semen Sesami, mostly be unsaturated fatty acid greatly, the effect of life prolonging is arranged; 14, Rhizoma Dioscoreae: contain protein, lymphatic temperament, choline, starch acid, aminoacid, carotene, vitamin B
1, vitamin B
2, hydrochloric acid, vitamin C etc., Rhizoma Dioscoreae is suitable to people of all ages food, can eat for a long time.Rhizoma Dioscoreae has strengthening the spleen and tonifying the lung, the beneficial essence effects such as antidiarrheal of reinforcing the kidney, quench the thirst.Can treat weak Mental fatigue, inappetence, dyspepsia, chronic diarrhea, cough due to consumptive disease, seminal emission night sweat, women leucorrhea, diabetes etc.; 15, Fructus Crataegi: have another name called Fructus Pyracanthae, Fructus Pyri Pashiae, kermes fruit, red Chinese date, tamarind seed etc., Fructus Crataegi contains protein, fat carbohydrate, crude fibre calcium, phosphorus, ferrum, vitamin C and vitamin B
1, vitamin B
1, vitamin B2, carotene, hydrochloric acid, Crataegolic acid, citric acid, compositions such as flavonoid.Fructus Crataegi can protect into gastric secretion, thereby increases peptic digestion, enzyme facilitating digestion, and Fructus Crataegi has promoting digestion and removing stagnation, the effects such as dissipating blood stasis, astringing to arrest diarrhea, sterilization of regulating the flow of vital energy, and also can be used for treating arteriosclerosis, hypertension, cardiovascular disease such as champion's cardiopathia and cardiac insufficiency.Act on and extremely importantly obvious curative effects is arranged preventing and treating hypertension, hyperlipidemia, coronary heart disease; 16, crystal sugar: have invigorating the spleen and replenishing QI, stomach function regulating lung moistening, cough-relieving turn to functions such as expectorant, heat clearing away the turbid descending, YIN nourishing and the production of body fluid promoting, hidroschesis detoxifcation, can be used for treating deficiency of QI in middle-JIAO, cough due to lung-heat, deficiency of YIN chronic cough, dryness of the mouth and throat, diseases such as laryngopharynx swelling and pain, infantile night sweat, aphtha, acute toothache; 17, Fructus Mori: nature and flavor are sweet, cold.GUIXIN liver, kidney channel.Effect: nourishing YIN and supplementing blood, the intestine moistening of promoting the production of body fluid.Be used for the cloudy blood deficiency of losing, dizzy, order dark, tinnitus, insomnia, early whitening of beard and hair.It is thirsty or quench one's thirst to be used for Tianjin wound.Be used for cloudy dryness of the intestine constipation of losing blood deficiency; 18, Fructus Hordei Germinatus: nature and flavor, sweet, flat.Return spleen, stomach, Liver Channel.Effect: help digestion and in, galactopoiesis.Be used for accumulation of food in the stomach and intes tine due to indigestion, dyspepsia, diseases such as anorexia, the vexed abdominal distention of gastral cavity; 19, Fructus Jujubae: contain compositions such as protein, fat, saccharide, carotene, vitamin B group, vitamin C, Citrin and phosphorus, calcium, ferrum, ascorbic content wherein, coming out at the top in fruit has the laudatory title of " vitamin pill ".The cyclic adenosine monophosphate that Fructus Jujubae is rich in is the essential material of human energy metabolism, the energy muscle strength reinforcing, and allaying tiredness, blood vessel dilating increases myocardial contraction, improves myocardial nutrition, to preventing and treating cardiovascular disease good effect is arranged.Fructus Jujubae has the tonify deficiency QI invigorating, nourishing blood to tranquillize the mind, and effects such as invigorating the spleen and regulating the stomach are weakness of the spleen and stomach, insufficiency of vital energy and blood, lassitude, insomnia waits patient's good health care nutriment.Fructus Jujubae is to acute and chronic, hepatitis, liver cirrhosis, and anemia, diseases such as anaphylactoid purpura have curative effect preferably.Fructus Jujubae contains triterpenoid compound and cyclic adenosine monophosphate, and the stronger cancer anti-allergic effects that presses down is arranged; 20, Auricularia: contain protein, fat, element and carotene such as polysaccharide and calcium, phosphorus, ferrum, vitamin B
1, vitamin B
2, hydrochloric acid etc., also contain phospholipid, nutrients such as sterin, decomposition can take place to tumor in the polysaccharide that Auricularia is contained, and improves body immunity, has antitumaous effect.Auricularia and nourishing is arranged, moisturize, the stomach reinforcing that nourishes blood, anti-ageing effect of prolonging life is an eipathia asthenia, lassitude loin and legs, numb limbs and tense tendons, anemia, hypertension, coronary heart disease, the ideal rehabilitation product of patients such as cerebral thrombosis, cancer; 21, apricot pink: nature and flavor hardship, tepor, detoxifcation.Return lung, large intestine channel.Effect, relieving cough and asthma, loosening bowel to relieve constipation.Be used for cough and asthma, the dryness of the intestine constipation; 22, Mel: nutritional labeling is extremely enriched it and is contained glucose, fructose, multiple acids, multiple organic acid, protein, multivitamin, kind of mineral surplus in the of 40 but not fatty.Mel has invigorating middle warmer to be moisturized, relieving spasm to stop pain, and the blood pressure lowering relieving constipation, effects such as drug abuse, gas loses empty xeropulmonary cough, rubella, gastropathy, diseases such as aphtha, burn due to hot liquid or fire, hypertension, chronic constipation in can be used for treating.Mel has the effect of strengthening body resistance, can make the people energetic, adjusts spleen and stomach function to gastritis, constipation, and gastric and duodenal ulcers has therapeutical effect preferably, and the energy removing the necrotic tissue and promoting granulation, adds the piece wound healing.But the often edible Mel cardiac nutrition of cardiac also has certain curative effect to neurasthenia's regulating liver-QI enteropathy people.The glucose and the fructose of Mel have protective effect to liver.
Since adopted such scheme to make a kind of treatment gastric cancer of invention, esophageal carcinoma, hepatocarcinoma, the pulmonary carcinoma colorectal carcinoma, cancer of pancreas, the carcinoma of tongue nasopharyngeal carcinoma, the yeast for brewing rice wine cost of thyroid carcinoma is low, good effect, instant effect, and have no side effect.
Below be detailed prescription of the present invention and processing technology: Fructus Mume 30 grams, Semen Euryales 60 grams, Semen Coicis 60 grams, Seem Lablab Album 60 grams, Semen Phaseoli 60 grams, Radix Ginseng 30 grams, Poria 60 grams, Tremella 60 grams, Semen Juglandis branch festival 150 grams, Semen oryzae sativae 120 grams, Semen Juglandis 30 grams, Semen Raphani 20 grams, Semen Sesami Nigrum 30 grams, Rhizoma Dioscoreae 120 grams, Fructus Crataegi 30 grams, crystal sugar 30 grams, Fructus Mori 60 grams, Fructus Hordei Germinatus 60 grams, Fructus Jujubae 60 grams, Auricularia 60 gram, Semen Armeniacae Amarum 30 grams, Mel 30 grams are with high-quality grain Chinese liquor 52 degree, 5000 milliliters.
The above medicine of processing technology of the present invention (except the Chinese liquor) makes choice of to wash and floats, the stir-fry method, and baking, the poison that confuses adds Chinese liquor 52 degree and invaded bubble 15-30 days, adds three days after-filtration of Mel, removes short, bristly hair or beard, and being up to the standards gets final product.
Claims (1)
1, a kind of medicated wine for the treatment of cancer is characterized in that it is to be made of the following weight ratio: Fructus Mume 30 grams, Semen Euryales 60 grams, Semen Coicis 60 grams, Seem Lablab Album 60 grams, Semen Phaseoli 60 grams, Radix Ginseng 30 grams, Poria 60 grams, Tremella 60 grams, Semen Juglandis branch festival 150 grams, Semen oryzae sativae 120 grams, Semen Juglandis 30 grams, Semen Raphani 20 grams, Semen Sesami Nigrum 30 grams, Rhizoma Dioscoreae 120 grams, Fructus Crataegi 30 grams, crystal sugar 30 grams, Fructus Mori 60 grams, Fructus Hordei Germinatus 60 grams, Fructus Jujubae 60 grams, Auricularia 60 grams, Semen Armeniacae Amarum 30 gram, Mel 30 grams are with high-quality grain Chinese liquor 52 degree, 5000 milliliters.
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| CN 200510073277 CN1698875A (en) | 2005-06-06 | 2005-06-06 | Medicinal wine for treatment of cancer |
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| CN 200510073277 CN1698875A (en) | 2005-06-06 | 2005-06-06 | Medicinal wine for treatment of cancer |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961402A (en) * | 2010-08-24 | 2011-02-02 | 张立顺 | Nutrient medicinal wine for treating asthma and invigorating spleen and kidney |
| CN101711855B (en) * | 2009-12-24 | 2011-10-05 | 天津中天制药有限公司 | Traditional Chinese medicine preparation for treating gastric cancer and preparation method |
| CN102274428A (en) * | 2011-07-18 | 2011-12-14 | 常熟雷允上制药有限公司 | Pharmaceutical composition with effect on treating irritable bowel syndrome and preparation method and application thereof |
| CN103263500A (en) * | 2013-04-16 | 2013-08-28 | 阚兆云 | Traditional Chinese medicine extract and preparation method thereof |
| CN104605387A (en) * | 2015-02-10 | 2015-05-13 | 王亚利 | Nutritional herbal cuisine capable of relieving postoperation radiotherapy response of cancer patient |
| CN104800321A (en) * | 2015-04-15 | 2015-07-29 | 江苏省中医院 | Application of dark plum fruit and extract of dark plum fruit in preparation of drug or health care product for controlling CRC (colorectal cancer) |
| CN106318814A (en) * | 2016-08-23 | 2017-01-11 | 安徽阳光药业有限公司 | Kidney-tonifying and essence-securing semen euryales wine and preparation method thereof |
-
2005
- 2005-06-06 CN CN 200510073277 patent/CN1698875A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101711855B (en) * | 2009-12-24 | 2011-10-05 | 天津中天制药有限公司 | Traditional Chinese medicine preparation for treating gastric cancer and preparation method |
| CN101961402A (en) * | 2010-08-24 | 2011-02-02 | 张立顺 | Nutrient medicinal wine for treating asthma and invigorating spleen and kidney |
| CN102274428A (en) * | 2011-07-18 | 2011-12-14 | 常熟雷允上制药有限公司 | Pharmaceutical composition with effect on treating irritable bowel syndrome and preparation method and application thereof |
| CN103263500A (en) * | 2013-04-16 | 2013-08-28 | 阚兆云 | Traditional Chinese medicine extract and preparation method thereof |
| CN104605387A (en) * | 2015-02-10 | 2015-05-13 | 王亚利 | Nutritional herbal cuisine capable of relieving postoperation radiotherapy response of cancer patient |
| CN104800321A (en) * | 2015-04-15 | 2015-07-29 | 江苏省中医院 | Application of dark plum fruit and extract of dark plum fruit in preparation of drug or health care product for controlling CRC (colorectal cancer) |
| CN104800321B (en) * | 2015-04-15 | 2018-01-05 | 江苏省中医院 | The application of dark plum and its extract in preventing and treating bowelcancer medicine or health products are prepared |
| CN106318814A (en) * | 2016-08-23 | 2017-01-11 | 安徽阳光药业有限公司 | Kidney-tonifying and essence-securing semen euryales wine and preparation method thereof |
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Open date: 20051123 |