CN1686492A - Antibicrobial anti inflammatory capsule and its preparation method - Google Patents
Antibicrobial anti inflammatory capsule and its preparation method Download PDFInfo
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- CN1686492A CN1686492A CN 200510200229 CN200510200229A CN1686492A CN 1686492 A CN1686492 A CN 1686492A CN 200510200229 CN200510200229 CN 200510200229 CN 200510200229 A CN200510200229 A CN 200510200229A CN 1686492 A CN1686492 A CN 1686492A
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Abstract
A antibacterial inflammation-relieving capsule for treating acute or chronic inflammation is prepared proportionally from savatier monochasma herb, oldenlandia and doyflower herb.
Description
Technical field:
The present invention relates to a kind of heat-clearing and toxic substances removing that has, pharmaceutical preparation of anti-inflammtory anti-dysentery effect and preparation method thereof.
Technical background:
The infectious disease serious threat people's life and health.Treatment for infectious disease mainly is the application of various antibiotics at present, but the Resistant strain that multiple reason causes constantly increases, and makes antibiotic curative effect constantly descend, and the infectious disease sickness rate rises, and the treatment difficulty strengthens.Therefore, seeking a kind of safe, anti-inflammation class medicine efficiently, is a great problem that medical circle faces.
Motherland's Chinese medicine has the incomparable advantage of Western medicine in this respect, and a large amount of heat-clearing and toxic substances removing is arranged in the Chinese medicine, and antibacterial and anti-inflammation functions has fully obtained modern pharmacology and experimental results show that.In the existing anti-inflammation class Chinese medicine, " scorching peaceful granule " is more a kind of, but because its dosage form and technologic defective in use also exist and take effect slowly, takes problems such as inconvenience.
Summary of the invention:
The objective of the invention is to: provide a kind of and on former medicine basis, change original technology, its extraction ratio of effective constituents is increased greatly, can better increase its clinical efficacy, to overcome the deficiency of existing medicine.
The present invention is achieved in that it is mainly made by following Chinese medicine raw materials by weight proportion in 1000 dosage units: 2000～5000 parts of Herba monochasmatiss, 1000～3000 parts of Herba Hedyotidis Diffusaes, 1000～3000 parts of Herba Commelinaes.
Wherein the consumption of crude drug is: 3906 parts of Herba monochasmatiss, 1953 parts of Herba Hedyotidis Diffusaes, 1953 parts of Herba Commelinaes.
Wherein also be added with adjuvant lubricant 0.2-1 part.
Described lubricant is magnesium stearate or micropowder silica gel, preferred micropowder silica gel.
Its preparation method is: above three flavors, decoct with water secondary, and add 10 times of water gagings for the first time, soak 30min, decocted 1.5 hours, and added 8 times of water gagings for the second time, decocted collecting decoction 1.0 hours, filter, filtrate is concentrated into relative density 1.10 (85～90 ℃), adds ethanol and makes that to contain the alcohol amount be 60%, stirs evenly, left standstill 12 hours, and filtered, filtrate is concentrated into the clear paste that relative density is 1.32 (85～90 ℃), drying, pulverize, granulate drying, granulate, add lubricant, fill, promptly.
The present invention compared with prior art has good effect, advantages such as taking convenience.Compare with Western medicine, the present invention have antibiotic extensively, overcome the Western medicine drug resistance, thoroughly kill bacteria virus, diminish inflammation; Effect is rapid, curative effect is high, generally take and took effect the same day, 3? it cures (acute); The sterilization sterilization thoroughly improves leukocytes phagocytic power, the radical cure active chronic inflammation; Pure Chinese medicine extraction, the characteristics that have no side effect.
Below beneficial effect by pharmacological evaluation explanation medicine of the present invention:
In order to verify that the present invention has antibacterial and anti-inflammation functions, the clinical experiment of having organized 100 people to participate in, wherein male 68 examples, women 32 examples; Age 1-15 year person's 36 examples, 16-35 year person's 42 examples, 36-50 year person's 16 examples, person's 6 examples more than 50 years old; The course of disease three days with interior person's 66 examples, a week, January was with interior person's 4 examples with interior person's 8 examples in ten days with interior person's 22 examples.
During treating, give 4/time, 3 times/day.Take month surplusly continuously, treatment back clinical symptoms all disappears, and stool routine examination transfers to normally, and the body temperature blood examination is normal and observe and follow up a case by regular visits to the person of not sending out a week and be healing.This group took 5 days and more person's 32 examples account for 32%.Took 7 days and more person's 42 examples account for 42%.Took 15 days and more person's 17 examples account for 17%.Took 30 days and more person's 9 examples account for 9%.Cure rate is 100%.
Wherein Herba monochasmatis acrid in the mouth hardship in the side is warm in nature.Expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation.Control traumatic injury, rheumatic arthritis, hepatitis, jaundice.Cold in nature, the sweet-bitter flavor of Herba Hedyotidis Diffusae, GUIXIN, lung, liver, large intestine channel have the effect of heat-clearing and toxic substances removing, convergence dampness removing, eliminating carbuncle eliminating stagnation.Modern pharmacological research confirms that Herba Hedyotidis Diffusae has the effect of anti-inflammation, antitumor, antiviral, raise immunity.Herba Commelinae is sweet, light, and is cold.Return lung, stomach, small intestine meridian.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.Be used for anemopyretic cold, hyperpyrexia, laryngopharynx swelling and pain, edema oliguria, the puckery pain of pyretic stranguria, carbuncle furunculosis.Three's prescription mutual reinforcement between mutual-assistance to the treatment respiratory tract infection, tonsillitis, diseases such as urinary tract infection have effect preferably.
The specific embodiment:
Embodiments of the invention: take by weighing deer Roripa grass 39068; Herba Hedyotidis Diffusae 1953g, Herba Commelinae 1953g decoct with water secondary, add 10 times of water gagings for the first time, soak 30min, decoct 1.5 hours, for the second time add 8 times of water gagings, decocted 1.0 hours, collecting decoction filters, filtrate is concentrated into relative density 1.10 (85～90 ℃), adds ethanol and makes that to contain alcohol amount be 60%, stirs evenly, and leaves standstill 12 hours, filter, filtrate is concentrated into the clear paste that relative density is 1.32 (85～90 ℃), and drying is pulverized, granulate drying, granulate, add micropowder silica gel 4.0g, fill, promptly get 1000.
Claims (5)
1. Antibicrobial anti inflammatory capsule, it is characterized in that: in 1000 dosage units, it is mainly made by following Chinese medicine raw materials by weight proportion: 2000～5000 parts of Herba monochasmatiss, 1000～3000 parts of Herba Hedyotidis Diffusaes, 1000～3000 parts of Herba Commelinaes.
2. capsule according to claim 1 is characterized in that: wherein the consumption of crude drug is: 3906 parts of Herba monochasmatiss, 1953 parts of Herba Hedyotidis Diffusaes, 1953 parts of Herba Commelinaes.
3. capsule according to claim 1 and 2 is characterized in that: wherein also be added with adjuvant lubricant 0.2-1 part.
4. capsule according to claim 3 is characterized in that: described lubricant is magnesium stearate or micropowder silica gel, preferred micropowder silica gel.
5. capsular according to claim 1 preparation method is characterized in that: above three flavors decoct with water secondary, add for the first time 10 times of water gagings, soak 30min, decocted 1.5 hours, for the second time add 8 times of water gagings, decocted collecting decoction 1.0 hours, filter, filtrate is concentrated into relative density 1.10 (85～90 ℃), adds ethanol and makes that to contain the alcohol amount be 60%, stir evenly, left standstill 12 hours, and filtered, filtrate is concentrated into the clear paste that relative density is 1.32 (85～90 ℃), dry, pulverize, granulate drying, granulate, add lubricant, fill, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510200229 CN1686492A (en) | 2005-04-11 | 2005-04-11 | Antibicrobial anti inflammatory capsule and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510200229 CN1686492A (en) | 2005-04-11 | 2005-04-11 | Antibicrobial anti inflammatory capsule and its preparation method |
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| Publication Number | Publication Date |
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| CN1686492A true CN1686492A (en) | 2005-10-26 |
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| CN 200510200229 Pending CN1686492A (en) | 2005-04-11 | 2005-04-11 | Antibicrobial anti inflammatory capsule and its preparation method |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258615A (en) * | 2011-06-25 | 2011-11-30 | 哈药集团三精千鹤制药有限公司 | Yanning capsule and preparation method thereof |
| CN102335272A (en) * | 2011-09-28 | 2012-02-01 | 哈尔滨市康隆药业有限责任公司 | Liquid preparation for diminishing inflammation and preparation method thereof |
| CN102488779A (en) * | 2011-12-31 | 2012-06-13 | 苏州大学 | Application of extract of Antlerpilose grass |
| CN110787104A (en) * | 2018-08-20 | 2020-02-14 | 惠州市九惠制药股份有限公司 | Compound traditional Chinese medicine toothpaste and preparation method and application thereof |
-
2005
- 2005-04-11 CN CN 200510200229 patent/CN1686492A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258615A (en) * | 2011-06-25 | 2011-11-30 | 哈药集团三精千鹤制药有限公司 | Yanning capsule and preparation method thereof |
| CN102335272A (en) * | 2011-09-28 | 2012-02-01 | 哈尔滨市康隆药业有限责任公司 | Liquid preparation for diminishing inflammation and preparation method thereof |
| CN102335272B (en) * | 2011-09-28 | 2013-09-04 | 哈尔滨市康隆药业有限责任公司 | Liquid preparation for diminishing inflammation and preparation method thereof |
| CN102488779A (en) * | 2011-12-31 | 2012-06-13 | 苏州大学 | Application of extract of Antlerpilose grass |
| CN102488779B (en) * | 2011-12-31 | 2014-02-26 | 苏州大学 | Application of extract of Antlerpilose grass |
| CN110787104A (en) * | 2018-08-20 | 2020-02-14 | 惠州市九惠制药股份有限公司 | Compound traditional Chinese medicine toothpaste and preparation method and application thereof |
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