CN1686450A - Summer heat clearing toxin resolving granules and its preparation method - Google Patents

Summer heat clearing toxin resolving granules and its preparation method Download PDF

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Publication number
CN1686450A
CN1686450A CN 200510069259 CN200510069259A CN1686450A CN 1686450 A CN1686450 A CN 1686450A CN 200510069259 CN200510069259 CN 200510069259 CN 200510069259 A CN200510069259 A CN 200510069259A CN 1686450 A CN1686450 A CN 1686450A
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parts
flos lonicerae
heat clearing
summer heat
preparation
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CN 200510069259
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CN100339118C (en
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张佳翼
高尚
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ANBANG PHARMACEUTIC Co Ltd HUNAN PROV
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Abstract

A Chinese medicine in the form of particles for antipyresis, detoxication and preventing and treating furuncle and heat rash is prepared from 7 Chinese-medicinal materials including reed rhizome, mint, honeysuckle flower, liquorice root, etc. Its preparing process is also disclosed.

Description

Summer heat clearing toxin resolving granules and preparation method thereof
Technical field
The present invention relates to a kind of summer heat clearing toxin resolving Chinese medicine, also related to this preparation method of Chinese medicine simultaneously.
Background technology
Summer since weather hot there was dampness in the air, intravital damp and hot being difficult to of human body discharged, so that space between skin and muscles obturation, sweating are not smooth, clinical symptoms shows as easy living sudamen and furuncle, and thirsty, xerostomia, heatstroke symptom occur.Equally, under hot environment, carry out operation,, xerostomia, thirsty and heatstroke phenomenon also can occur, all affect health of people because excessive sweating or intimate heat can not distribute.The medicine that is used at present prevent to suffer heatstroke is to form principal agent with Radix Glycyrrhizae, Herba Menthae, Flos Lonicerae and Spica Prunellae etc., and the Spica Prunellae consumption is higher in its principal agent, makes resultant effect not really desirable.In addition, very high as consumptions such as the citric acid of adjuvant and sucrose, make that not only mouthfeel is relatively poor, and easily cause part crowd gastrointestinal upset because of citric acid consumption height, particularly too high sugar content can be brought a lot of side effect concerning the diabetes patient, also makes the cost of pharmacy corporation increase in addition.
Summary of the invention
Purpose of the present invention just is to provide a kind of summer heat clearing toxin resolving Chinese medicine, has that clearing away summer-heat is analgesic, the promoting the production of body fluid to quench thirst effect, and can prevent and treat sudamen and furuncle.
Summer heat clearing toxin resolving granules provided by the invention, it is the granule of making by following materials based on weight, 140 parts~170 parts of Rhizoma Phragmitiss, 43 parts~50 parts of Herba Menthaes, 140 parts~170 parts of Flos Loniceraes, 56 parts~68 parts in Radix Glycyrrhizae, 140 parts~170 parts of Herba Lophatheris, 140 parts~170 parts of Pulvis Talci, 85 parts~103 parts of Spica Prunellaes, and right amount of auxiliary materials, wherein contain Flos Lonicerae with chlorogenic acid C in every bag of product 16H 18O 9Meter is not less than 13.0 milligrams.
Preferred mode is that summer heat clearing toxin resolving granules is made by the raw material of following weight parts: 156 parts of Rhizoma Phragmitiss, 47 parts of Herba Menthaes, 156 parts of Flos Loniceraes, 62 parts in Radix Glycyrrhizae, 156 parts of Herba Lophatheris, 156 parts of Pulvis Talci, 94 parts of Spica Prunellaes, adjuvant are 20 parts of 830 parts of cane sugar powders and citric acid.
The present invention also provides a kind of preparation method of above-mentioned summer heat clearing toxin resolving granules, by to extracting mode to be optimized, make that medicinal composition extracts more abundant in each raw material, to guarantee its therapeutic effect, this method side is made up of following step: distill after Flos Lonicerae and Herba Menthae are added water infiltration, and it is standby to collect volatile oil, and its medicinal liquid is filtered filtrate for later use; Flos Lonicerae and Herba Menthae medicinal residues and all the other raw materials are decocted with water the back to be filtered, filtrate and Flos Lonicerae and Herba Menthae filtrate are merged, be condensed into paste, through vacuum drying and after being ground into fine powder, add adjuvant and make granule, spray into the volatile oil and an amount of essence of extraction then.
The water consumption that described Flos Lonicerae and Herba Menthae are soaked into is preferably Flos Lonicerae and Herba Menthae weight 8 times.
The distillation time of described Flos Lonicerae and Herba Menthae is preferably 5.5~6.5 hours, most preferably 6 hours, fully to extract volatile oil, prevents the loss of this part medicinal component.
Described Flos Lonicerae medicinal residues and all the other raw materials decoct with water the process preferably twice, add 8 times of water gagings for the first time and decoct 2 hours, add 7 times of water gagings for the second time and decoct 1.5 hours, fully to extract the water solublity medicinal component.
For ease of drying, the relative density of the ointment after concentrating is good with 1.30 (60 ℃ of surveys).
To be 60~70 ℃, vacuum be-0.08Mpa to the preferred temperature of described vacuum drying operating condition.
Rhizoma Phragmitis clearing away heat and promoting production of body fluid in the side; The Herba Menthae antalgesic-antipruritic, dispel the heat, ward off dirty, the detoxifcation; Flos Lonicerae has the effect of heat clearing away, detoxifcation, removing heat from blood, dredge the meridian passage, and its Main Ingredients and Appearance is a chlorogenic acid, and chlorogenic acid has the effect of anti-inflammation clinically; The Radix Glycyrrhizae heat-clearing and toxic substances removing; Herba Lophatheri clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid; Skin ulcer is held back in Pulvis Talci heat-clearing and toxic substances removing, damp eliminating; Spica Prunellae heat-clearing and toxic substances removing, hard masses softening and resolving.Heat-clearing and toxic substances removing medicine of the present invention by Chinese medicine is carried out rationally, the science compatibility, drug storage is collaborative, heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst effect are remarkable, and can prevent and treat the sudamen and furuncle that causes because of weather is damp and hot, are used for summer-heat and each treatment heatstroke of prevention and miliaria alba etc. during work in hot environment in summer.
This preparation method of the present invention, characteristics according to each raw material, Flos Lonicerae and Herba Menthae and other each raw material of Chinese medicine are extracted respectively, make the volatility medicinal component and be difficult for volatile medicinal component and all can fully extract, and gradation adds use, guaranteed that the volatility medicinal component does not run off, improved the content of medicinal composition in the product medicine, strengthened drug effect.Cane sugar powder and citric acid consumption as adjuvant in the granule all are lower than supplementary product consumption in the granule commonly used, by it being carried out the science collocation under the prerequisite that guarantees figuration and flavoring effect, the discomfort reaction that has improved mouthfeel and the intestines and stomach is caused and to diabetes patient's adverse effect, also reduced production cost, can also improve the content of efficacy component, be beneficial to effectively absorb and improve medicine, reach the purpose that increases therapeutic effect at blood middle concentration.
The specific embodiment
Below in conjunction with specific embodiment summer heat clearing toxin resolving granules of the present invention and preparation method thereof is described further, in the following examples,, then wherein contains Flos Lonicerae with chlorogenic acid C in every bag of product in every bagged granules agent 8 grams 16H 18O 9Meter is not less than 13.0 milligrams.。
Embodiment 1
The clearing away summer-heat granule is made by following raw material. and principal agent is Rhizoma Phragmitis 156 grams, Herba Menthae 47 grams, Flos Lonicerae 156 grams, Radix Glycyrrhizae 62 grams, Herba Lophatheri 156 grams, Pulvis Talci 156 grams, Spica Prunellae 94 grams, and adjuvant is cane sugar powder 830 grams, citric acid 20 grams.
1, Flos Lonicerae and the Herba Menthae with above-mentioned weight adds 8 times of water gagings, soaks into 1 hour, distills 6 hours, collects the volatile oil that distills out, and with medical filtration, filtrate for later use;
2, the medicinal residues of Flos Lonicerae and Herba Menthae are added all the other Chinese medicine of the five flavours raw materials again and decoct together, decoct at twice, add 8 times of water gagings for the first time, decocted 2 hours, add 7 times of water gagings decoctions 1.5 hours for the second time; Merge decocting liquid twice, filter;
3, after merging through filtered medicine liquid in 1 and 2, be concentrated into the thick paste that relative density is 1.30 (60 ℃ of surveys);
4, being 60~70 ℃, vacuum with above-mentioned thick paste in temperature carries out vacuum drying under-0.08Mpa the condition;
5, dried medicine is ground into fine powder, adds cane sugar powder 830 grams, citric acid 20 grams, mixing, granulation, drying, granulate, and spray into volatile oil and an amount of essence that extracts in 1, mixing is made the product material of 1000 grams approximately, and pack is promptly.
Every packed 8 grams, boiled water is taken after mixing it with water or buccal, one time 1 bag, 4~5 times on the one.
Embodiment 2
The clearing away summer-heat granule is made by following raw material, and principal agent is Rhizoma Phragmitis 140 grams, Herba Menthae 50 grams, Flos Lonicerae 140 grams, Radix Glycyrrhizae 68 grams, Herba Lophatheri 140 grams, Pulvis Talci 170 grams, Spica Prunellae 85 grams, and adjuvant (adjuvant commonly used in the available granule preparation) is an amount of.
1, Flos Lonicerae and the Herba Menthae with above-mentioned weight adds 7.8 times of water gagings, soaks into 1 hour, distills 6.2 hours, collects the volatile oil that distills out, and with medical filtration, filtrate for later use;
2, Flos Lonicerae and Herba Menthae medicinal residues are added all the other five tastes medicines again and decoct, add 8.2 times of water gagings for the first time, decocted 2.2 hours, add 6.8 times of water gagings decoctions 1.5 hours for the second time; Merge decocting liquid twice, filter;
3, after the process filtered medicine liquid merges in the step 1 and 2, be concentrated into the thick paste that relative density is 1.3 (60 ℃ of surveys);
4, above-mentioned thick paste is carried out vacuum drying at 60~70 ℃, vacuum under-0.08Mpa the condition;
5, dried medicine is ground into fine powder, adds adjuvant, mixing, granulation, drying, granulate; And spray into the volatile oil of extraction in the step 1 and an amount of essence, and mixing is made 1000 a product material that restrain approximately, and pack is promptly.Every packed 8 grams, boiled water is taken after mixing it with water or buccal, one time 1 bag, 4~5 times on the one.
Embodiment 3
The clearing away summer-heat granule is made by following raw material, and Rhizoma Phragmitis 170 restrains, Herba Menthae 43 restrains, Flos Lonicerae 170 restrains, Radix Glycyrrhizae 56 restrains, Herba Lophatheri 170 restrains, Pulvis Talci 140 restrains, Spica Prunellae 103 restrains, and sucrose part 900 restrains, citric acid 220 restrains as adjuvant.
1, Flos Lonicerae and the Herba Menthae with above-mentioned weight adds 8 times of water gagings, soaks into 1 hour, distills 6 hours, collects the volatile oil that distills out, and with medical filtration, filtrate for later use;
2, Flos Lonicerae and Herba Menthae medicinal residues are added all the other five tastes medicines again and decoct, add 8 times of water gagings for the first time, decocted 2 hours, add 7 times of water gagings decoctions 1.5 hours for the second time; Merge decocting liquid twice, filter;
3, after the process filtered medicine liquid merges in the step 1 and 2, be concentrated into the thick paste that relative density is 1.30 (60 ℃ of surveys);
4, above-mentioned thick paste is carried out vacuum drying at 60~70 ℃, vacuum under-0.08Mpa the condition;
5, dried medicine is ground into fine powder, adds cane sugar powder, citric acid adjuvant, mixing, granulation, drying, granulate; And spray into the volatile oil of extraction in the step 1 and an amount of essence, and mixing is made 1000 a product material that restrain approximately, and pack is promptly.Every packed 8 grams, boiled water is taken after mixing it with water or buccal, one time 1 bag, 4~5 times on the one.

Claims (10)

1, a kind of summer heat clearing toxin resolving granules, make by following materials based on weight: 140 parts~170 parts of Rhizoma Phragmitiss, 43 parts~50 parts of Herba Menthaes, 140 parts~170 parts of Flos Loniceraes, 56 parts~68 parts in Radix Glycyrrhizae, 140 parts~170 parts of Herba Lophatheris, 140 parts~170 parts of Pulvis Talci, 85 parts~103 parts of Spica Prunellaes, and right amount of auxiliary materials
Wherein contain Flos Lonicerae in every bag of product and be not less than 13.0 milligrams in chlorogenic acid C16H18O9.
2, summer heat clearing toxin resolving granules according to claim 1, it is characterized in that this granule made by the raw material of following weight parts: 156 parts of Rhizoma Phragmitiss, 47 parts of Herba Menthaes, 156 parts of Flos Loniceraes, 62 parts in Radix Glycyrrhizae, 156 parts of Herba Lophatheris, 156 parts of Pulvis Talci, 94 parts of Spica Prunellaes, adjuvant are 20 parts of 830 parts of cane sugar powders and citric acid.
3, the preparation method of the described summer heat clearing toxin resolving granules of a kind of claim 1 is characterized in that this method is made up of following step: distill after Flos Lonicerae and Herba Menthae are added water infiltration, and it is standby to collect volatile oil, and then its medicinal liquid is filtered filtrate for later use; Flos Lonicerae and Herba Menthae medicinal residues and all the other raw materials are decocted with water the back to be filtered, filtrate and Flos Lonicerae and Herba Menthae filtrate are merged, be condensed into paste, through vacuum drying and after being ground into fine powder, add adjuvant and make granule, spray into the volatile oil and an amount of essence of extraction then.
4, the preparation method of summer heat clearing toxin resolving granules according to claim 3, the water yield that it is characterized in that described Flos Lonicerae and Herba Menthae infiltration usefulness are Flos Lonicerae and Herba Menthae weight 8 times.
5, the preparation method of summer heat clearing toxin resolving granules according to claim 3, the infiltrating time that it is characterized in that described Flos Lonicerae and Herba Menthae is 1 hour.
6, the preparation method of summer heat clearing toxin resolving granules according to claim 3, the distillation time that it is characterized in that described Flos Lonicerae and Herba Menthae is 5.5~6.5 hours, most preferably 6 hours.
7, the preparation method of summer heat clearing toxin resolving granules according to claim 3 is characterized in that it is twice that described Flos Lonicerae medicinal residues and all the other raw materials decoct with water process, adds 8 times of water gagings for the first time and decocts 2 hours, adds 7 times of water gagings for the second time and decocts 1.5 hours.
8, the preparation method of summer heat clearing toxin resolving granules according to claim 3, the relative density of the ointment after it is characterized in that concentrating is 1.30 (60 ℃ of surveys).
9, the preparation method of summer heat clearing toxin resolving granules according to claim 3 is characterized in that described vacuum drying operating condition is 60~70 ℃ of temperature, vacuum-0.08Mpa.
10, the preparation method of summer heat clearing toxin resolving granules according to claim 3, it is characterized in that described adjuvant is 830 parts of cane sugar powders, 20 parts of citric acid, with granulation behind the fine powder mixing that is ground into, dry, granulate, spray into volatile oil and an amount of essence of the Flos Lonicerae and the Herba Menthae of extraction again, mixing is made granule.
CNB2005100692592A 2005-05-13 2005-05-13 Summer heat clearing toxin resolving granules and its preparation method Active CN100339118C (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102550754A (en) * 2011-12-28 2012-07-11 何贤福 Bitter gourd herbal tea and preparation method of bitter gourd herbal tea
CN102960565A (en) * 2012-11-28 2013-03-13 江汉大学 Natural plant chicken heat stress resistant feed addictive and preparation method thereof
CN103800711A (en) * 2012-11-14 2014-05-21 沈锋艳 Preparation method of preparation for clearing away summer-heat and eliminating toxin
CN106344842A (en) * 2016-08-26 2017-01-25 山东医学高等专科学校 Soup with effects of clearing summer heat and activating spleen and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102550754A (en) * 2011-12-28 2012-07-11 何贤福 Bitter gourd herbal tea and preparation method of bitter gourd herbal tea
CN103800711A (en) * 2012-11-14 2014-05-21 沈锋艳 Preparation method of preparation for clearing away summer-heat and eliminating toxin
CN102960565A (en) * 2012-11-28 2013-03-13 江汉大学 Natural plant chicken heat stress resistant feed addictive and preparation method thereof
CN102960565B (en) * 2012-11-28 2014-07-09 江汉大学 Natural plant chicken heat stress resistant feed addictive and preparation method thereof
CN106344842A (en) * 2016-08-26 2017-01-25 山东医学高等专科学校 Soup with effects of clearing summer heat and activating spleen and preparation method thereof

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Address after: No.283 Kangning Road, Liuyang economic and Technological Development Zone, Changsha City, Hunan Province

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