CN1772153A - Compound Chinese medicine prepn for treating pulvic infection and its prepn process - Google Patents

Compound Chinese medicine prepn for treating pulvic infection and its prepn process Download PDF

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CN1772153A
CN1772153A CN 200510096118 CN200510096118A CN1772153A CN 1772153 A CN1772153 A CN 1772153A CN 200510096118 CN200510096118 CN 200510096118 CN 200510096118 A CN200510096118 A CN 200510096118A CN 1772153 A CN1772153 A CN 1772153A
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radix
parts
preparation
rhizoma
angelicae sinensis
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CN1298362C (en
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丁玉兰
慕慧霞
辛秀芳
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Gansu Xifeng Pharmaceutical Co.,Ltd.
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XIFENG PHARMACEUTICAL FACTORY GANSU MEDICINE GROUP
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Abstract

The compound Chinese medicine preparation for treating pulvic infection is prepared with patrinia herb, plantain seed, dandelion, nutagrass flatsedge rhizome, red peony root and other 15 kinds of Chinese medicinal materials. The preparation process includes the steps of: decoction, percolating and extracting aromatic component, alcohol solution precipitation to eliminate impurity, drying, crushing, pelletizing and packing. The present invention has certain curative effect on pulvic infection and curative rate over 90 %, and is safe and convenient. The preparation process has simple operation, reasonable technological process and good maintenance of the effective components in the medicine materials.

Description

A kind of compound Chinese medicinal preparation for the treatment of pelvic inflammatory disease and preparation method thereof
Technical field
The present invention relates to be used for the treatment of the Chinese medicine preparation of gynecological inflammation, is a kind of compound Chinese medicinal preparation that is used for the treatment of pelvic inflammatory disease specifically, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Pelvic inflammatory disease is the general name of women uterus, fallopian tube, ovary, pelvic peritoneum and inflammation of pelvic connective tissue disease.Main pathogenic bacterium have escherichia coli, staphylococcus aureus, streptococcus and anaerobe.Clinical manifestation according to pelvic inflammatory disease can be divided into acute and chronic two kinds again.The chronic pelvic inflammatory disease main clinic symptoms has lower abdomen pain, lumbosacral aching pain, profuse leukorrhea, lower abdomen caking or companion to see heating etc.The traditional Chinese medical science does not have " in the disease such as chronic pelvic inflammatory disease " name of disease, according to its clinical manifestation, Yu “ mass in the abdomen sporadically appears ", " dysmenorrhea ", " leukorrhagia ".Chronic pelvic inflammatory disease is commonly encountered diseases, frequently-occurring disease, and sickness rate is higher, and touching difficulty more, has a strong impact on women's physical and mental health.According to Cui Shi report, " 1992~1993 years to 4723 the women's generaI investigations in Guangzhou, ill 253 people, wherein adnexitis accounts for 0.64% " [1]Again according to Henan Medical Univ. " the pelvic inflammatory disease sickness rate was 3.02% to the 1516 people's survey results of married woman below 60 years old in institute's jurisdiction section in 1987 " [2]" 6286 women of the anti-group generaI investigation of group in 1977~1979 years find pelvic inflammatory disease 439 examples, prevalence 6.98% according to another Wuhan medical college first Affiliated Hospital [3]As seen, chronic pelvic inflammatory disease has higher sickness rate in numerous women, and state of an illness stubbornness, and touching difficulty more.Though the chronic pelvic inflammatory disease method of treatment is many, route of administration is many, and curative effect is dissatisfied, and it is thorny that the worker of gynecological feels very much.Have severally though specially control for oral administration accurate font size Chinese medicine of chronic pelvic inflammatory disease in the market, do not satisfy patient's need.Chronic pelvic inflammatory disease is common gynecological disease, frequently-occurring disease, and this sick easily trials and tribulations is healed, and numerous women's physical and mental health in serious harm.At present, it is more to treat this sick medicine, but most medicine especially the anti-inflammation class cure the symptoms, not the disease, and antibiotic has bigger toxic and side effects for a long time with easily producing drug resistance.It is pure Chinese medicinal preparation that the woman can make tranquil capsule, and clinical test results proves that this medicine is safe and effective, and stable and controllable can play the effect for the treatment of both the principal and secondary aspects of a disease to pelvic inflammatory disease.
Summary of the invention
The purpose of this invention is to provide a kind of treatment rate and can reach evident in efficacy more than 90%, taking convenience, and also preparation method is easy, keeps a kind of compound Chinese medicinal preparation for the treatment of pelvic inflammatory disease of medicine active ingredient and preparation method thereof to greatest extent.
The object of the present invention is achieved like this:
A kind of compound Chinese medicinal preparation for the treatment of pelvic inflammatory disease is prepared from by the following weight proportion raw material:
Sonchus brachyotus DC. 16-30 part Semen Plantaginis 13-24 part Herba Taraxaci 8-15 part
Rhizoma Cyperi 7-12 part Radix Paeoniae Rubra 5-9 part Flos Carthami 5-9 part
Radix Salviae Miltiorrhizae 8-15 part Rhizoma Corydalis 8-15 part Radix Notoginseng 3-6 part
Radix Gentianae Macrophyllae 8-15 part Cortex Lycii 7-12 part Carapax Trionycis 5-9 part
Sargassum 13-24 part Radix Codonopsis 8-15 part Rhizoma Atractylodis Macrocephalae 5-9 part
Poria 7-12 part Radix Rehmanniae Preparata 7-12 part Radix Angelicae Sinensis 8-15 part
Herba Portulacae 8-15 part Radix Bupleuri 8-15 part.
The better weight proportion of above-mentioned each raw material is:
Sonchus brachyotus DC. 16-24 part Semen Plantaginis 13-20 part Herba Taraxaci 8-12 part
Rhizoma Cyperi 7-10 part Radix Paeoniae Rubra 5-7 part Flos Carthami 5-7 part
Radix Salviae Miltiorrhizae 8-12 part Rhizoma Corydalis 8-12 part Radix Notoginseng 3-5 part
Radix Gentianae Macrophyllae 8-12 part Cortex Lycii 7-10 part Carapax Trionycis 5-7 part
Sargassum 13-20 part Radix Codonopsis 8-12 part Rhizoma Atractylodis Macrocephalae 5-7 part
Poria 7-12 part Radix Rehmanniae Preparata 7-12 part Radix Angelicae Sinensis 8-15 part
Herba Portulacae 8-12 part Radix Bupleuri 8-12 part
The best weight proportion of aforementioned each raw material is:
10 parts of 16 parts of Herba Taraxacis of 20 portions of Semen Plantaginiss of Sonchus brachyotus DC.
6 parts on 6 parts of Flos Carthamis of 8 parts of Radix Paeoniae Rubra of Rhizoma Cyperi
4 parts of 10 portions of Radix Notoginseng of 10 parts of Rhizoma Corydalis of Radix Salviae Miltiorrhizae
6 parts of 8 parts of Carapax Trionycis of 10 parts of Cortex Lycii of Radix Gentianae Macrophyllae
6 parts of 10 parts of Rhizoma Atractylodis Macrocephalaes of 16 parts of Radix Codonopsis of Sargassum
10 parts of 8 parts of Radix Angelicae Sinensis of 8 parts of Radix Rehmanniaes Preparata of Poria
10 parts of 10 parts of Radix Bupleuri of Herba Portulacae
Its preparation method is: the Radix Notoginseng in the raw material, Poria powder are become fine powder; Rhizoma Corydalis, Radix Gentianae Macrophyllae are ground into coarse powder, carry out percolation with 70~85% ethanol as solvent; Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis add the water distillation, extract volatile oil, airtight preservation, and cooking liquor filters standby; Carapax Trionycis decocted 1 hour earlier, merge decoction with Sonchus brachyotus DC., Semen Plantaginis, Herba Taraxaci, Radix Paeoniae Rubra, Flos Carthami, Radix Salviae Miltiorrhizae, Cortex Lycii, Sargassum, Radix Codonopsis, Radix Rehmanniae Preparata, Herba Portulacae, Radix Bupleuri 12 flavor raw materials after leaching decocting liquid, add the water that 8-10 doubly measures at every turn, decoct twice, merge decoction liquor. filter, merge with the cooking liquor of Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, be concentrated into the clear paste that relative density is 1.15-1.2; When putting, add ethanol and make and contain alcohol amount and reach 60~70%, left standstill 24 hours to 35~45 ℃, precipitated impurities, precipitate with ethanol supernatant and percolate merge, decompression recycling ethanol, filter, filtrate decompression is condensed into thick paste, adds Radix Notoginseng, Poria fine powder, drying is pulverized, and adds 10~20% starch, granulate, drying sprays into volatile oil, packing, promptly.
The present invention has certain effect to chronic pelvic inflammatory disease, and treatment rate reaches more than 90%, and taking convenience.This preparation method is easy and simple to handle, and technological design is reasonable, keeps the medicine active ingredient to greatest extent.
Clinical research data:
(1) II phase clinical research
Test group is gone into group 102 examples, is met scheme data set 100 examples;
Matched group is gone into group 105 examples, meets scheme data set 99 examples.
The tcm symptom curative effect
Test group 100 examples: clinic control 18.0%, produce effects 42%, progressive 36%, invalid 5%.
Matched group 99 examples: clinic control 12.1%, produce effects 37.4%, progressive 38.4%, invalid 12.1%.
Local Signs curative effect
Test group 100 examples: clinic control 15.0%, produce effects 42%, progressive 32%, invalid 11%.
Matched group 99 examples: clinic control 9.1%, produce effects 40.4%, progressive 31.3%, invalid 19.2%.
(2) III phase clinical research
Test group is gone into group 324 examples, meets scheme data set 319 examples
Matched group is gone into group 108 examples, meets scheme data set 104 examples
The tcm symptom curative effect
Test group 319 examples: clinic control 15.4%, produce effects 40.8%, progressive 35.7%, invalid 8.2%.
Matched group 104 examples: clinic control 4.8%, produce effects 34.6%, progressive 46.2%, invalid 14.4%.
Local Signs curative effect
Test group 319 examples: clinic control 21.6%, produce effects 27.0%, progressive 42.9%, invalid 8.5%.
Matched group 104 examples: clinic control 14.4%, produce effects 26.0%, progressive 40.4%, invalid 19.2%.
(3) validity result: above statistical result showed, tcm symptom curative effect and local Signs curative effect relatively has a significant difference between two groups, and test group is better than matched group
(4) safety results: test group II, III clinical research go into to organize case 426 examples altogether, and not observing has anomalous effects to the heart, liver, renal function, blood system, the security inspection no abnormality seen
From the statistical analysis of above curative effect as seen, the present invention treats chronic pelvic inflammatory disease (hot and humid ecchymosis pents up card) curative effect preferably, main curative effect is better than matched group, security inspection no abnormality seen, so the conclusion of treatment pelvic inflammatory disease (hot and humid ecchymosis pents up card) clinical experimental study is: it is safe and effective that the present invention treats pelvic inflammatory disease (hot and humid ecchymosis pents up card).
Instructions of taking: oral, one time 3,3 times on the one.
The specific embodiment
Preparation method of the present invention is taked crude drug in whole adding, decocting in water, percolation and extraction armaticity composition, and has taked alcoholic solution precipitation partial impurities, final drying, pulverizes, makes corresponding dosage form, packing technology.Adding accounts for the dextrin of total amount 20~30% when preparation granule dosage form, 50~60% white sugar is made in the present invention.
Embodiment 1
Get: Sonchus brachyotus DC. 200g Semen Plantaginis 160g Herba Taraxaci 100g
Rhizoma Cyperi 80g Radix Paeoniae Rubra 60g Flos Carthami 60g
Radix Salviae Miltiorrhizae 100g Rhizoma Corydalis 100g Radix Notoginseng 40g
Radix Gentianae Macrophyllae 100g Cortex Lycii 80g Carapax Trionycis 60g
Sargassum 160g Radix Codonopsis 100g Rhizoma Atractylodis Macrocephalae 60g
Poria 80g Radix Rehmanniae Preparata 80g Radix Angelicae Sinensis 100g
Herba Portulacae 100g Radix Bupleuri 100g
Prepare by following process:
1, the Radix Notoginseng in the raw material, Poria powder are become fine powder,, cross sieve No. six, flour extraction is 95% ± 0.5%, it is standby to endorse; Rhizoma Corydalis, Radix Gentianae Macrophyllae are ground into coarse powder, cross sieve No. 2, make solvent with 75% ethanol, carry out percolation with the speed of kilogram medical material per minute 5ml, collect percolate, and device is preserved in addition;
2, Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis add water distillation 6 hours, and 8 times of each amount of water are collected volatile oil 0.5~0.7ml (pressing recipe quantity), airtight preservation, and cooking liquor filters standby;
3, Carapax Trionycis decocted 1 hour earlier, merge decoction with Sonchus brachyotus DC., Semen Plantaginis, Herba Taraxaci, Radix Paeoniae Rubra, Flos Carthami, Radix Salviae Miltiorrhizae, Cortex Lycii, Sargassum, Radix Codonopsis, Radix Rehmanniae Preparata, Herba Portulacae, Radix Bupleuri 12 flavor raw materials after leaching decocting liquid, the water that at every turn adds 8 times of amounts, decoct twice, merge decoction liquor. filter, merge with the cooking liquor of Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, be concentrated into relative density and be 1.15 clear paste;
When 4, putting 35 ℃, add ethanol and make and contain alcohol amount and reach 60~70%, left standstill 24 hours, precipitated impurities, precipitate with ethanol supernatant and percolate merge, decompression recycling ethanol, filter, filtrate decompression is condensed into thick paste, adds Radix Notoginseng, Poria fine powder, drying is pulverized, and adds 10% starch, granulate, drying sprays into volatile oil, packing, promptly.By every dress 0.36g, each 3, every day 3 times.
Embodiment 2
Sonchus brachyotus DC. 160g Semen Plantaginis 130g Herba Taraxaci 80g
Rhizoma Cyperi 70g Radix Paeoniae Rubra 050g Flos Carthami 50g
Radix Salviae Miltiorrhizae 080g Rhizoma Corydalis 80g Radix Notoginseng 30g
Radix Gentianae Macrophyllae 080g Cortex Lycii 70g Carapax Trionycis 50g
Sargassum 130g Radix Codonopsis 80g Rhizoma Atractylodis Macrocephalae 90g
Poria 70g Radix Rehmanniae Preparata 120g Radix Angelicae Sinensis 150g
Herba Portulacae 150g Radix Bupleuri 150g
Prepare by following process:
1, the Radix Notoginseng in the raw material, Poria powder are become fine powder; Rhizoma Corydalis, Radix Gentianae Macrophyllae are ground into coarse powder, carry out percolation with 70% ethanol as solvent;
2, Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis add the water distillation, extract volatile oil, airtight preservation, and cooking liquor filters standby;
3, Carapax Trionycis decocted 1 hour earlier, merge decoction with Sonchus brachyotus DC., Semen Plantaginis, Herba Taraxaci, Radix Paeoniae Rubra, Flos Carthami, Radix Salviae Miltiorrhizae, Cortex Lycii, Sargassum, Radix Codonopsis, Radix Rehmanniae Preparata, Herba Portulacae, Radix Bupleuri 12 flavor raw materials after leaching decocting liquid, the water that at every turn adds 8 times of amounts, decoct twice, merge decoction liquor. filter, merge with the cooking liquor of Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, be concentrated into relative density and be 1.2 clear paste;
When 4, putting, add ethanol and make and contain alcohol amount and reach 60~70%, left standstill 24 hours to 45 ℃, precipitated impurities, precipitate with ethanol supernatant and percolate merge, decompression recycling ethanol, filter, filtrate decompression is condensed into thick paste, adds Radix Notoginseng, Poria fine powder, drying is pulverized, and adds 10% starch, granulate, drying sprays into volatile oil, tabletting, coating promptly gets the woman and can make tranquil tablet.By every heavy 0.36g, each 3, every day 3 times.
Embodiment 3
Sonchus brachyotus DC. 300g Semen Plantaginis 240g Herba Taraxaci 150g
Rhizoma Cyperi 120g Radix Paeoniae Rubra 90g Flos Carthami 90g
Radix Salviae Miltiorrhizae 150g Rhizoma Corydalis 150g Radix Notoginseng 60g
Radix Gentianae Macrophyllae 150g Cortex Lycii 120g Carapax Trionycis 90g
Sargassum 240g Radix Codonopsis 150g Rhizoma Atractylodis Macrocephalae 50g
Poria 120g Radix Rehmanniae Preparata 70g Radix Angelicae Sinensis 80g
Herba Portulacae 80g Radix Bupleuri 80g
Prepare by following process:
1, the Radix Notoginseng in the raw material, Poria powder are become fine powder; Rhizoma Corydalis, Radix Gentianae Macrophyllae are ground into coarse powder, carry out percolation with 85% ethanol as solvent;
2, Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis add the water distillation, extract volatile oil, airtight preservation, and cooking liquor filters standby;
3, Carapax Trionycis decocted 1 hour earlier, merge decoction with Sonchus brachyotus DC., Semen Plantaginis, Herba Taraxaci, Radix Paeoniae Rubra, Flos Carthami, Radix Salviae Miltiorrhizae, Cortex Lycii, Sargassum, Radix Codonopsis, Radix Rehmanniae Preparata, Herba Portulacae, Radix Bupleuri 12 flavor raw materials after leaching decocting liquid, the water that at every turn adds 10 times of amounts, decoct twice, merge decoction liquor. filter, merge with the cooking liquor of Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, be concentrated into relative density and be 1.15 clear paste;
When 4, putting, add ethanol and make and contain alcohol amount and reach 60~70%, left standstill 24 hours to 35 ℃, precipitated impurities, precipitate with ethanol supernatant and percolate merge, decompression recycling ethanol, filter, filtrate decompression is condensed into thick paste, adds Radix Notoginseng, Poria fine powder, drying is pulverized, and adds 436g dextrin, 869g sugar, granulate, drying sprays into volatile oil, packing promptly gets the woman and can make tranquil granule.By every packed 5g, each 1 bag, every day 3 times.
Embodiment 4
Sonchus brachyotus DC. 160g Semen Plantaginis 130g Herba Taraxaci 80g
Rhizoma Cyperi 70g Radix Paeoniae Rubra 50g Flos Carthami 50g
Radix Salviae Miltiorrhizae 80g Rhizoma Corydalis 80g Radix Notoginseng 30g
Radix Gentianae Macrophyllae 80g Cortex Lycii 70g Carapax Trionycis 50g
Sargassum 130g Radix Codonopsis 80g Rhizoma Atractylodis Macrocephalae 70g
Poria 70g Radix Rehmanniae Preparata 120g Radix Angelicae Sinensis 150g
Herba Portulacae 120g Radix Bupleuri 120g
Preparation method is with embodiment 2.
Embodiment 5
Sonchus brachyotus DC. 240g Semen Plantaginis 200g Herba Taraxaci 120g
Rhizoma Cyperi 100g Radix Paeoniae Rubra 70g Flos Carthami 70g
Radix Salviae Miltiorrhizae 120g Rhizoma Corydalis 120g Radix Notoginseng 50g
Radix Gentianae Macrophyllae 120g Cortex Lycii 100g Carapax Trionycis 70g
Sargassum 200g Radix Codonopsis 120g Rhizoma Atractylodis Macrocephalae 50g
Poria 120g Radix Rehmanniae Preparata 70g Radix Angelicae Sinensis 80g
Herba Portulacae 80g Radix Bupleuri 80g
Preparation method is with embodiment 3.

Claims (10)

1, a kind of compound Chinese medicinal preparation for the treatment of pelvic inflammatory disease is characterized in that being prepared from by the following weight proportion raw material:
Sonchus brachyotus DC. 16-30 part Semen Plantaginis 13-24 part Herba Taraxaci 8-15 part
Rhizoma Cyperi 7-12 part Radix Paeoniae Rubra 5-9 part Flos Carthami 5-9 part
Radix Salviae Miltiorrhizae 8-15 part Rhizoma Corydalis 8-15 part Radix Notoginseng 3-6 part
Radix Gentianae Macrophyllae 8-15 part Cortex Lycii 7-12 part Carapax Trionycis 5-9 part
Sargassum 13-24 part Radix Codonopsis 8-15 part Rhizoma Atractylodis Macrocephalae 5-9 part
Poria 7-12 part Radix Rehmanniae Preparata 7-12 part Radix Angelicae Sinensis 8-15 part
Herba Portulacae 8-15 part Radix Bupleuri 8-15 part.
2, a kind of compound Chinese medicinal preparation for the treatment of pelvic inflammatory disease according to claim 1 is characterized in that the weight proportion of described raw material is:
Sonchus brachyotus DC. 16-24 part Semen Plantaginis 13-20 part Herba Taraxaci 8-12 part
Rhizoma Cyperi 7-10 part Radix Paeoniae Rubra 5-7 part Flos Carthami 5-7 part
Radix Salviae Miltiorrhizae 8-12 part Rhizoma Corydalis 8-12 part Radix Notoginseng 3-5 part
Radix Gentianae Macrophyllae 8-12 part Cortex Lycii 7-10 part Carapax Trionycis 5-7 part
Sargassum 13-20 part Radix Codonopsis 8-12 part Rhizoma Atractylodis Macrocephalae 5-7 part
Poria 7-12 part Radix Rehmanniae Preparata 7-12 part Radix Angelicae Sinensis 8-15 part
Herba Portulacae 8-12 part Radix Bupleuri 8-12 part.
3, a kind of compound Chinese medicinal preparation for the treatment of pelvic inflammatory disease according to claim 1 is characterized in that the weight proportion of described raw material is:
10 parts of 16 parts of Herba Taraxacis of 20 portions of Semen Plantaginiss of Sonchus brachyotus DC.
6 parts on 6 parts of Flos Carthamis of 8 parts of Radix Paeoniae Rubra of Rhizoma Cyperi
4 parts of 10 portions of Radix Notoginseng of 10 parts of Rhizoma Corydalis of Radix Salviae Miltiorrhizae
6 parts of 8 parts of Carapax Trionycis of 10 parts of Cortex Lycii of Radix Gentianae Macrophyllae
6 parts of 10 parts of Rhizoma Atractylodis Macrocephalaes of 16 parts of Radix Codonopsis of Sargassum
10 parts of 8 parts of Radix Angelicae Sinensis of 8 parts of Radix Rehmanniaes Preparata of Poria
10 parts of 10 parts of Radix Bupleuri of Herba Portulacae.
4, a kind of preparation is characterized in that according to following technical process preparation as the preparation method of the compound Chinese medicinal preparation of treatment pelvic inflammatory disease as described in claim 1 or 2 or 3:
Radix Notoginseng in the raw material, Poria powder are become fine powder; Rhizoma Corydalis, Radix Gentianae Macrophyllae are ground into coarse powder, carry out percolation with 70~85% ethanol as solvent; Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis add the water distillation, extract volatile oil, airtight preservation, and cooking liquor filters standby; Carapax Trionycis decocted 1 hour earlier, merge decoction with Sonchus brachyotus DC., Semen Plantaginis, Herba Taraxaci, Radix Paeoniae Rubra, Flos Carthami, Radix Salviae Miltiorrhizae, Cortex Lycii, Sargassum, Radix Codonopsis, Radix Rehmanniae Preparata, Herba Portulacae, Radix Bupleuri 12 flavor raw materials after leaching decocting liquid, add the water that 8-10 doubly measures at every turn, decoct twice, merge decoction liquor. filter, merge with the cooking liquor of Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, be concentrated into the clear paste that relative density is 1.15-1.2; When putting, add ethanol and make and contain alcohol amount and reach 60~70%, left standstill 24 hours to 35~45 ℃, precipitated impurities, precipitate with ethanol supernatant and percolate merge, decompression recycling ethanol, filter, filtrate decompression is condensed into thick paste, adds Radix Notoginseng, Poria fine powder, drying is pulverized, and adds 10~20% starch, granulate, drying sprays into volatile oil, packing, promptly.
5, preparation method according to claim 4 is characterized in that described Radix Notoginseng, Poria powder become fine powder, crosses sieve No. six, and flour extraction is 95% ± 0.5%, and it is standby to endorse.
6, preparation method according to claim 4 is characterized in that described Rhizoma Corydalis, Radix Gentianae Macrophyllae are ground into coarse powder, crosses sieve No. two, makes solvent with 70~85% ethanol, carries out percolation with the speed of kilogram medical material per minute 3~6ml, collects percolate, and device is preserved in addition.
7, preparation method according to claim 4 is characterized in that described Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis extract volatile oil, is that Rhizoma Cyperi, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis are added water, distilled 6 hours, 8~10 times of each amount of water are collected volatile oil, airtight preservation, cooking liquor filters standby.
8, preparation method according to claim 4 is characterized in that relative density that described filtrate decompression is condensed into thick paste is 1.15~1.30 thick paste, and receiving the cream rate is 10.11% ± 1%.
9, preparation method according to claim 4 is characterized in that described adjuvant is a starch.
10, the preparation method of compound Chinese medicinal preparation according to claim 4 is characterized in that described compound Chinese medicinal preparation can make various dosage forms according to conventional method.
CN 200510096118 2005-09-29 2005-09-29 Compound Chinese medicine prepn for treating pulvic infection and its prepn process Active CN1298362C (en)

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CN101966325A (en) * 2010-10-28 2011-02-09 南京市中医院 Medicament for treating damp-heat stasis blocking type endometriosis and preparation method thereof
CN102973731A (en) * 2011-09-05 2013-03-20 王成光 Pelvic inflammatory disease and dysmenorrheal treatment liquid agent and preparation method thereof
CN104606593A (en) * 2015-01-12 2015-05-13 翔宇药业股份有限公司 Preparation process of dandelion-rhizoma smilacis glabrae pelvic inflammation-curing capsule preparation
CN110179893A (en) * 2019-06-18 2019-08-30 南宁市妇幼保健院 Ten tastes ginseng returns enema fluid and its preparation process

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101966325A (en) * 2010-10-28 2011-02-09 南京市中医院 Medicament for treating damp-heat stasis blocking type endometriosis and preparation method thereof
CN101966325B (en) * 2010-10-28 2011-11-16 南京市中医院 Medicament for treating damp-heat stasis blocking type endometriosis and preparation method thereof
CN102973731A (en) * 2011-09-05 2013-03-20 王成光 Pelvic inflammatory disease and dysmenorrheal treatment liquid agent and preparation method thereof
CN104606593A (en) * 2015-01-12 2015-05-13 翔宇药业股份有限公司 Preparation process of dandelion-rhizoma smilacis glabrae pelvic inflammation-curing capsule preparation
CN110179893A (en) * 2019-06-18 2019-08-30 南宁市妇幼保健院 Ten tastes ginseng returns enema fluid and its preparation process
CN110179893B (en) * 2019-06-18 2021-12-03 南宁市妇幼保健院 Enema liquid of ten ingredients with ginseng and angelica and preparation process thereof

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