CN1063077C - Traditional Chinese medicine composition for lowering blood-lipid, and method for preparing same - Google Patents
Traditional Chinese medicine composition for lowering blood-lipid, and method for preparing same Download PDFInfo
- Publication number
- CN1063077C CN1063077C CN 98100188 CN98100188A CN1063077C CN 1063077 C CN1063077 C CN 1063077C CN 98100188 CN98100188 CN 98100188 CN 98100188 A CN98100188 A CN 98100188A CN 1063077 C CN1063077 C CN 1063077C
- Authority
- CN
- China
- Prior art keywords
- radix
- rhizoma
- curcumae
- weight portion
- curcumae longae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 69
- 239000000203 mixture Substances 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title description 11
- 210000004369 blood Anatomy 0.000 claims abstract description 51
- 239000008280 blood Substances 0.000 claims abstract description 51
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 31
- 239000008187 granular material Substances 0.000 claims abstract description 25
- 238000002360 preparation method Methods 0.000 claims abstract description 24
- 239000000284 extract Substances 0.000 claims abstract description 23
- 238000002156 mixing Methods 0.000 claims abstract description 14
- 238000001035 drying Methods 0.000 claims abstract description 9
- 239000003390 Chinese drug Substances 0.000 claims description 55
- 239000000843 powder Substances 0.000 claims description 41
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims description 25
- 239000009636 Huang Qi Substances 0.000 claims description 21
- 239000000706 filtrate Substances 0.000 claims description 21
- 239000012530 fluid Substances 0.000 claims description 20
- 239000011230 binding agent Substances 0.000 claims description 15
- 239000008517 radix Trichosanthis Substances 0.000 claims description 15
- 238000001914 filtration Methods 0.000 claims description 12
- 238000010298 pulverizing process Methods 0.000 claims description 11
- 238000002791 soaking Methods 0.000 claims description 8
- 240000001341 Reynoutria japonica Species 0.000 claims description 6
- 235000018167 Reynoutria japonica Nutrition 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 235000003392 Curcuma domestica Nutrition 0.000 claims description 4
- 235000003373 curcuma longa Nutrition 0.000 claims description 4
- 235000013976 turmeric Nutrition 0.000 claims description 4
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 244000163122 Curcuma domestica Species 0.000 claims 2
- 235000014375 Curcuma Nutrition 0.000 claims 1
- 241000219780 Pueraria Species 0.000 claims 1
- 241000233948 Typha Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 21
- 239000007788 liquid Substances 0.000 abstract description 9
- 238000005516 engineering process Methods 0.000 abstract description 6
- 231100000331 toxic Toxicity 0.000 abstract description 6
- 230000002588 toxic effect Effects 0.000 abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 3
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 3
- 239000000853 adhesive Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 description 32
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 18
- 241000699670 Mus sp. Species 0.000 description 14
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 11
- 239000002994 raw material Substances 0.000 description 10
- 210000002966 serum Anatomy 0.000 description 9
- 210000002784 stomach Anatomy 0.000 description 9
- 230000017531 blood circulation Effects 0.000 description 8
- 238000009835 boiling Methods 0.000 description 8
- 239000000796 flavoring agent Substances 0.000 description 8
- 235000019634 flavors Nutrition 0.000 description 8
- 150000003626 triacylglycerols Chemical class 0.000 description 8
- 229940079593 drug Drugs 0.000 description 7
- 230000037396 body weight Effects 0.000 description 6
- 230000008859 change Effects 0.000 description 6
- 235000012000 cholesterol Nutrition 0.000 description 6
- 230000003516 hyperlipidaemic effect Effects 0.000 description 6
- 231100000682 maximum tolerated dose Toxicity 0.000 description 6
- 208000031226 Hyperlipidaemia Diseases 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 208000035150 Hypercholesterolemia Diseases 0.000 description 4
- 231100000111 LD50 Toxicity 0.000 description 4
- 230000003203 everyday effect Effects 0.000 description 4
- 208000024172 Cardiovascular disease Diseases 0.000 description 3
- 244000008991 Curcuma longa Species 0.000 description 3
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 210000000582 semen Anatomy 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 3
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 238000011047 acute toxicity test Methods 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000000680 avirulence Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000000055 hyoplipidemic effect Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 206010008132 Cerebral thrombosis Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- HEMJJKBWTPKOJG-UHFFFAOYSA-N Gemfibrozil Chemical compound CC1=CC=C(C)C(OCCCC(C)(C)C(O)=O)=C1 HEMJJKBWTPKOJG-UHFFFAOYSA-N 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 241000228347 Monascus <ascomycete fungus> Species 0.000 description 1
- 241001597008 Nomeidae Species 0.000 description 1
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 229960001214 clofibrate Drugs 0.000 description 1
- KNHUKKLJHYUCFP-UHFFFAOYSA-N clofibrate Chemical compound CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 KNHUKKLJHYUCFP-UHFFFAOYSA-N 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000012531 culture fluid Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229960003627 gemfibrozil Drugs 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000008802 xuezhikang Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Blood fat situation before taking | Number | Blood fat situation of change after taking medicine one month | Number |
Triglyceride 300-575mg/dl | 100 | Triglyceride is reduced to 310-432mg/dl | 24 |
Cholesterol 265-308mg/dl | 11 | Cholesterol is reduced to≤250mg/dl | 3 |
Triglyceride does not have significant change or undesirable | 76 |
Blood fat situation before taking medicine | Number | Blood fat situation of change after taking medicine 1 month | Number |
Serum triglycerides 350-700mg/dl | 300 | Serum triglycerides is reduced to 130-200mg/dl | 317 |
Serum cholesterol 260-310mg/dl | 37 | Serum cholesterol is reduced to 166-230mg/dl | 37 |
Serum triglycerides does not have significant change | 3 |
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 98100188 CN1063077C (en) | 1998-02-06 | 1998-02-06 | Traditional Chinese medicine composition for lowering blood-lipid, and method for preparing same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 98100188 CN1063077C (en) | 1998-02-06 | 1998-02-06 | Traditional Chinese medicine composition for lowering blood-lipid, and method for preparing same |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1225265A CN1225265A (en) | 1999-08-11 |
CN1063077C true CN1063077C (en) | 2001-03-14 |
Family
ID=5215860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 98100188 Expired - Fee Related CN1063077C (en) | 1998-02-06 | 1998-02-06 | Traditional Chinese medicine composition for lowering blood-lipid, and method for preparing same |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1063077C (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102488128B (en) * | 2011-12-02 | 2013-09-25 | 马松江 | Food composition having function of assisting in depressing blood-fat and preparation method thereof |
CN104056184A (en) * | 2013-03-22 | 2014-09-24 | 曹昌银 | Traditional Chinese medicine health care composition for reducing blood lipid |
-
1998
- 1998-02-06 CN CN 98100188 patent/CN1063077C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1225265A (en) | 1999-08-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1079027C (en) | Pharmaceutical composition for diabetes | |
CN100349597C (en) | Chinese medicinal preparation for treating virus myocaraitis, its preparation method and quality control method | |
CN1840128A (en) | Medicine for treating cardiovascular disease | |
CN101856405B (en) | Medicinal composition for treating type II diabetes mellitus and preparation method thereof | |
CN1159050C (en) | Compound traditional Chinese medicine preparation for treating type 2 diabetes | |
CN101461932B (en) | Medicament composition for treating children's damp-heat diarrhea induced by spleen insufficiency and preparation method thereof | |
CN100341547C (en) | Medicinal composition for regulating blood fat, prepn. method and use thereof | |
CN1293898C (en) | Medicine composition for treating viral hepatitis and its preparation method | |
CN1298362C (en) | Compound Chinese medicine prepn for treating pulvic infection and its prepn process | |
CN1232279C (en) | Antilipemic Chinese medicine | |
CN1063077C (en) | Traditional Chinese medicine composition for lowering blood-lipid, and method for preparing same | |
CN102266538B (en) | Traditional Chinese medicinal composition for treating damp-heat dysentery and preparation method thereof | |
CN105250954B (en) | A kind of Chinese medicine for treating IBS and preparation method thereof | |
CN1772257A (en) | Fatty liver treating notoginseng prepn and its prepn process | |
CN1857599A (en) | Medicine for lowering blood sugar, blood fat and blood pressure, raising blood flow rate and raising immunity and its preparing method | |
CN105727089A (en) | Application of medicine composition containing folium artemisiae argyi to preparing medicine for treating irritable bowel syndrome | |
CN1051713C (en) | Umbellate pore fungus and poria cocos antidiarrhea oral liquid and its production technology | |
CN1087627C (en) | Medicament for treating diabetes and its preparation method | |
CN1136939A (en) | Chinese drugs for curing hepatitis B | |
CN1289111C (en) | Medicine for lowering blood lipid and softening blood vessel and its preparing method | |
CN1475261A (en) | Medicine for treating gastral cavity pain and its preparation method | |
CN1079396A (en) | Intelligence-enhancing pharmaceutical preparation | |
CN1126558C (en) | Medicine for treating kidney damage caused by immunological disease lupus erythematosus | |
CN100339093C (en) | Compound medicine for treating coronary heart disease and angina pectoris and its preparing process | |
CN1183933C (en) | Medicine for treating incomplete kidney function and its prepn |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: INNER MONGOLIAN MONGOLIAN MEDICINE TECHNOLOGY ENG Free format text: FORMER OWNER: YUAN GUOSHUN Effective date: 20080411 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20080411 Address after: B, 3rd floor, building No. 141, Xincheng West Street, Hohhot, Inner Mongolia Patentee after: Inner Mongolia Mongolian Medicine Technology Research Engineering Center Address before: Medical College Hospital, 8 East Main Street, Beijing, Fengtai District Patentee before: Yuan Guoshun |
|
ASS | Succession or assignment of patent right |
Owner name: ULANHOT ZHONGMENG PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: INNER MONGOLIA AUTONOMOUS REGION MONGOLIA MEDICINE TECHNOLOGICAL RESEARCH CENTER Effective date: 20150424 |
|
C41 | Transfer of patent application or patent right or utility model | ||
COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 010010 HOHHOT, INNER MONGOLIA AUTONOMOUS REGION TO: 137400 HINGGAN LEAGUE, INNER MONGOLIA AUTONOMOUS REGION |
|
TR01 | Transfer of patent right |
Effective date of registration: 20150424 Address after: Lian Sheng Jie Ulanhot city the Inner Mongolia Autonomous Region safety Lane 137400 No. 65 Patentee after: Ulanhot Zhongmeng Pharmaceutical Co., Ltd. Address before: 010010, B, building 141, Metro building, No. Xincheng West Street, the Inner Mongolia Autonomous Region, China Patentee before: Inner Mongolia Mongolian Medicine Technology Research Engineering Center |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20010314 Termination date: 20170206 |
|
CF01 | Termination of patent right due to non-payment of annual fee |