CN100339118C - Summer heat clearing toxin resolving granules and its preparation method - Google Patents
Summer heat clearing toxin resolving granules and its preparation method Download PDFInfo
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- CN100339118C CN100339118C CNB2005100692592A CN200510069259A CN100339118C CN 100339118 C CN100339118 C CN 100339118C CN B2005100692592 A CNB2005100692592 A CN B2005100692592A CN 200510069259 A CN200510069259 A CN 200510069259A CN 100339118 C CN100339118 C CN 100339118C
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Abstract
The present invention discloses a particle for clearing summer-heat and detoxification, which is made of the following raw materials with weight parts: 140 shares to 170 shares of reed roots, 43 shares to 50 shares of herba menthae, 140 shares to 170 shares of honeysuckle flowers, 56 shares to 68 shares of licorice roots, 140 shares to 170 shares of lophatherum herbs, 140 shares to 170 shares of talcum powders, 85 shares to 103 shares of spica prunellae and a proper quantities of supplementary materials, wherein the quality of the honeysuckle flowers in each bag of products is not less than 13.0 mg by the weight of Chlorogenic acid C16 H18 O9. The present invention also discloses a method for preparing the medicine. The honeysuckle flowers and the herba menthae are firstly distilled to extract volatile oil and physic liquor, herb residues and other raw materials are decocted, the physic liquor and the prior physic liquor of the honeysuckle flowers and the herba menthae are merged and then concentrated into paste for vacuum drying, and a finished product is prepared by adding in supplementary materials and the volatile oil after pulverization. The particle for clearing summer-heat and detoxification has the efficiency of fluid promoting and thirst quenching, summer-heat clearing and detoxification and miliaria heat bump prevention and cure.
Description
Technical field
The present invention relates to a kind of summer heat clearing toxin resolving Chinese medicine, also related to this preparation method of Chinese medicine simultaneously.
Background technology
Summer since weather hot there was dampness in the air, intravital damp and hot being difficult to of human body discharged, so that space between skin and muscles obturation, sweating are not smooth, clinical symptoms shows as easy living sudamen and furuncle, and thirsty, xerostomia, heatstroke symptom occur.Equally, under hot environment, carry out operation,, xerostomia, thirsty and heatstroke phenomenon also can occur, all affect health of people because excessive sweating or intimate heat can not distribute.The medicine that is used at present prevent to suffer heatstroke is to form principal agent with Radix Glycyrrhizae, Herba Menthae, Flos Lonicerae and Spica Prunellae etc., and the Spica Prunellae consumption is higher in its principal agent, makes resultant effect not really desirable.In addition, very high as consumptions such as the citric acid of adjuvant and sucrose, make that not only mouthfeel is relatively poor, and easily cause part crowd gastrointestinal upset because of citric acid consumption height, particularly too high sugar content can be brought a lot of side effect concerning the diabetes patient, also makes the cost of pharmacy corporation increase in addition.
Summary of the invention
Purpose of the present invention just is to provide a kind of summer heat clearing toxin resolving Chinese medicine, has that clearing away summer-heat is analgesic, the promoting the production of body fluid to quench thirst effect, and can prevent and treat sudamen and furuncle.
Summer heat clearing toxin resolving granules provided by the invention, it is the granule of making by following materials based on weight, 156 parts of Rhizoma Phragmitiss, 47 parts of Herba Menthaes, 156 parts of Flos Loniceraes, 62 parts in Radix Glycyrrhizae, 156 parts of Herba Lophatheris, 156 parts of Pulvis Talci, 94 parts of Spica Prunellaes, adjuvant is 20 parts of 830 parts of cane sugar powders and citric acid, wherein contains Flos Lonicerae with chlorogenic acid C in every bag of product
16H
18O
9Meter is not less than 13.0 milligrams.
The present invention also provides a kind of preparation method of above-mentioned summer heat clearing toxin resolving granules, by to extracting mode to be optimized, make that medicinal composition extracts more abundant in each raw material, to guarantee its therapeutic effect, this method side is made up of following step: weigh by prescription, distill after Flos Lonicerae and Herba Menthae are added water infiltration, and it is standby to collect volatile oil, and then with its medicinal liquid filtration, filtrate for later use; Flos Lonicerae and Herba Menthae medicinal residues and all the other raw materials are decocted with water the back to be filtered, filtrate and Flos Lonicerae and Herba Menthae filtrate are merged, be condensed into paste, through vacuum drying and after being ground into fine powder, granulation behind 830 parts of cane sugar powders of adding, 20 parts of mixings of citric acid, dry, granulate, spray into volatile oil and an amount of essence of the Flos Lonicerae and the Herba Menthae of extraction again, mixing is made granule.
The water consumption that described Flos Lonicerae and Herba Menthae are soaked into is preferably Flos Lonicerae and Herba Menthae weight 8 times.
The distillation time of described Flos Lonicerae and Herba Menthae is preferably 5.5～6.5 hours, most preferably 6 hours, fully to extract volatile oil, prevents the loss of this part medicinal component.
Described Flos Lonicerae medicinal residues and all the other raw materials decoct with water the process preferably twice, add 8 times of water gagings for the first time and decoct 2 hours, add 7 times of water gagings for the second time and decoct 1.5 hours, fully to extract the water solublity medicinal component.
For ease of drying, the relative density of the ointment after concentrating is good with 1.30 (60 ℃ of surveys).
To be 60～70 ℃, vacuum be-0.08Mpa to the preferred temperature of described vacuum drying operating condition.
Rhizoma Phragmitis clearing away heat and promoting production of body fluid in the side; The Herba Menthae antalgesic-antipruritic, dispel the heat, ward off dirty, the detoxifcation; Flos Lonicerae has the effect of heat clearing away, detoxifcation, removing heat from blood, dredge the meridian passage, and its Main Ingredients and Appearance is a chlorogenic acid, and chlorogenic acid has the effect of anti-inflammation clinically; The Radix Glycyrrhizae heat-clearing and toxic substances removing; Herba Lophatheri clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid; Skin ulcer is held back in Pulvis Talci heat-clearing and toxic substances removing, damp eliminating; Spica Prunellae heat-clearing and toxic substances removing, hard masses softening and resolving.Heat-clearing and toxic substances removing medicine of the present invention by Chinese medicine is carried out rationally, the science compatibility, drug storage is collaborative, heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst effect are remarkable, and can prevent and treat the sudamen and furuncle that causes because of weather is damp and hot, are used for summer-heat and each treatment heatstroke of prevention and miliaria alba etc. during work in hot environment in summer.
This preparation method of the present invention, characteristics according to each raw material, Flos Lonicerae and Herba Menthae and other each raw material of Chinese medicine are extracted respectively, make the volatility medicinal component and be difficult for volatile medicinal component and all can fully extract, and gradation adds use, guaranteed that the volatility medicinal component does not run off, improved the content of medicinal composition in the product medicine, strengthened drug effect.Cane sugar powder and citric acid consumption as adjuvant in the granule all are lower than supplementary product consumption in the granule commonly used, by it being carried out the science collocation under the prerequisite that guarantees figuration and flavoring effect, the discomfort reaction that has improved mouthfeel and the intestines and stomach is caused and to diabetes patient's adverse effect, also reduced production cost, can also improve the content of efficacy component, be beneficial to effectively absorb and improve medicine, reach the purpose that increases therapeutic effect at blood middle concentration.
The specific embodiment
Below in conjunction with specific embodiment summer heat clearing toxin resolving granules of the present invention and preparation method thereof is described further, in the following examples,, then wherein contains Flos Lonicerae with chlorogenic acid C in every bag of product in every bagged granules agent 8 grams
16H
18O
9Meter is not less than 13.0 milligrams.。
Embodiment 1
The clearing away summer-heat granule is made by following raw material, and principal agent is Rhizoma Phragmitis 156 grams, Herba Menthae 47 grams, Flos Lonicerae 156 grams, Radix Glycyrrhizae 62 grams, Herba Lophatheri 156 grams, Pulvis Talci 156 grams, Spica Prunellae 94 grams, and adjuvant is cane sugar powder 830 grams, citric acid 20 grams.
1, Flos Lonicerae and the Herba Menthae with above-mentioned weight adds 8 times of water gagings, soaks into 1 hour, distills 6 hours, collects the volatile oil that distills out, and with medical filtration, filtrate for later use;
2, the medicinal residues of Flos Lonicerae and Herba Menthae are added all the other Chinese medicine of the five flavours raw materials again and decoct together, decoct at twice, add 8 times of water gagings for the first time, decocted 2 hours, add 7 times of water gagings decoctions 1.5 hours for the second time; Merge decocting liquid twice, filter;
3, after merging through filtered medicine liquid in 1 and 2, be concentrated into the thick paste that relative density is 1.30 (60 ℃ of surveys);
4, being 60～70 ℃, vacuum with above-mentioned thick paste in temperature carries out vacuum drying under-0.08Mpa the condition;
5, dried medicine is ground into fine powder, adds cane sugar powder 830 grams, citric acid 20 grams, mixing, granulation, drying, granulate, and spray into volatile oil and an amount of essence that extracts in 1, mixing is made the product material of 1000 grams approximately, and pack is promptly.
Every packed 8 grams, boiled water is taken after mixing it with water or buccal, one time 1 bag, 4～5 times on the one.
Embodiment 2
The clearing away summer-heat granule is made by following raw material, and principal agent is Rhizoma Phragmitis 140 grams, Herba Menthae 50 grams, Flos Lonicerae 140 grams, Radix Glycyrrhizae 68 grams, Herba Lophatheri 140 grams, Pulvis Talci 170 grams, Spica Prunellae 85 grams, and adjuvant (adjuvant commonly used in the available granule preparation) is an amount of.
1, Flos Lonicerae and the Herba Menthae with above-mentioned weight adds 7.8 times of water gagings, soaks into 1 hour, distills 6.2 hours, collects the volatile oil that distills out, and with medical filtration, filtrate for later use;
2, Flos Lonicerae and Herba Menthae medicinal residues are added all the other five tastes medicines again and decoct, add 8.2 times of water gagings for the first time, decocted 2.2 hours, add 6.8 times of water gagings decoctions 1.5 hours for the second time; Merge decocting liquid twice, filter;
3, after the process filtered medicine liquid merges in the step 1 and 2, be concentrated into the thick paste that relative density is 1.3 (60 ℃ of surveys);
4, above-mentioned thick paste is carried out vacuum drying at 60～70 ℃, vacuum under-0.08Mpa the condition;
5, dried medicine is ground into fine powder, adds adjuvant, mixing, granulation, drying, granulate; And spray into the volatile oil of extraction in the step 1 and an amount of essence, and mixing is made 1000 a product material that restrain approximately, and pack is promptly.Every packed 8 grams, boiled water is taken after mixing it with water or buccal, one time 1 bag, 4～5 times on the one.
Embodiment 3
The clearing away summer-heat granule is made by following raw material, and Rhizoma Phragmitis 170 restrains, Herba Menthae 43 restrains, Flos Lonicerae 170 restrains, Radix Glycyrrhizae 56 restrains, Herba Lophatheri 170 restrains, Pulvis Talci 140 restrains, Spica Prunellae 103 restrains, and sucrose part 900 restrains, citric acid 220 restrains as adjuvant.
1, Flos Lonicerae and the Herba Menthae with above-mentioned weight adds 8 times of water gagings, soaks into 1 hour, distills 6 hours, collects the volatile oil that distills out, and with medical filtration, filtrate for later use;
2, Flos Lonicerae and Herba Menthae medicinal residues are added all the other five tastes medicines again and decoct, add 8 times of water gagings for the first time, decocted 2 hours, add 7 times of water gagings decoctions 1.5 hours for the second time; Merge decocting liquid twice, filter;
3, after the process filtered medicine liquid merges in the step 1 and 2, be concentrated into the thick paste that relative density is 1.30 (60 ℃ of surveys);
4, above-mentioned thick paste is carried out vacuum drying at 60～70 ℃, vacuum under-0.08Mpa the condition;
5, dried medicine is ground into fine powder, adds cane sugar powder, citric acid adjuvant, mixing, granulation, drying, granulate; And spray into the volatile oil of extraction in the step 1 and an amount of essence, and mixing is made 1000 a product material that restrain approximately, and pack is promptly.Every packed 8 grams, boiled water is taken after mixing it with water or buccal, one time 1 bag, 4～5 times on the one.
Claims (9)
1, a kind of summer heat clearing toxin resolving granules, raw material of Chinese medicine by following portions by weight is made: 156 parts of Rhizoma Phragmitiss, 47 parts of Herba Menthaes, 156 parts of Flos Loniceraes, 62 parts in Radix Glycyrrhizae, 156 parts of Herba Lophatheris, 156 parts of Pulvis Talci, 94 parts of Spica Prunellaes, adjuvant is 20 parts of 830 parts of cane sugar powders and citric acid
Wherein contain Flos Lonicerae with chlorogenic acid C in every bag of product
16H
18O
9Meter is not less than 13.0 milligrams.
2, the preparation method of the described summer heat clearing toxin resolving granules of a kind of claim 1, it is characterized in that this method is made up of following step: weigh by prescription, distill after Flos Lonicerae and Herba Menthae are added water infiltration, and it is standby to collect volatile oil, and then with its medicinal liquid filtration, filtrate for later use; Flos Lonicerae and Herba Menthae medicinal residues and all the other raw materials are decocted with water the back to be filtered, filtrate and Flos Lonicerae and Herba Menthae filtrate are merged, be condensed into paste, through vacuum drying and after being ground into fine powder, granulation behind 830 parts of cane sugar powders of adding, 20 parts of mixings of citric acid, dry, granulate, spray into volatile oil and an amount of essence of the Flos Lonicerae and the Herba Menthae of extraction again, mixing is made granule.
3, the preparation method of summer heat clearing toxin resolving granules according to claim 2, the water yield that it is characterized in that described Flos Lonicerae and Herba Menthae infiltration usefulness are Flos Lonicerae and Herba Menthae weight 8 times.
4, the preparation method of summer heat clearing toxin resolving granules according to claim 2, the infiltrating time that it is characterized in that described Flos Lonicerae and Herba Menthae is 1 hour.
5, the preparation method of summer heat clearing toxin resolving granules according to claim 2, the distillation time that it is characterized in that described Flos Lonicerae and Herba Menthae is 5.5～6.5 hours.
6, the preparation method of summer heat clearing toxin resolving granules according to claim 2, the distillation time that it is characterized in that described Flos Lonicerae and Herba Menthae is 6 hours.
7, the preparation method of summer heat clearing toxin resolving granules according to claim 2 is characterized in that it is twice that described Flos Lonicerae medicinal residues and all the other raw materials decoct with water process, adds 8 times of water gagings for the first time and decocts 2 hours, adds 7 times of water gagings for the second time and decocts 1.5 hours.
Relative density when 8, the preparation method of summer heat clearing toxin resolving granules according to claim 2,60 ℃ of the ointment after it is characterized in that concentrating is 1.30.
9, the preparation method of summer heat clearing toxin resolving granules according to claim 3 is characterized in that described vacuum drying operating condition is 60～70 ℃ of temperature, vacuum-0.08Mpa.
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|---|---|---|---|
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| CNB2005100692592A CN100339118C (en) | 2005-05-13 | 2005-05-13 | Summer heat clearing toxin resolving granules and its preparation method |
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| CN102550754A (en) * | 2011-12-28 | 2012-07-11 | 何贤福 | Bitter gourd herbal tea and preparation method of bitter gourd herbal tea |
| CN103800711A (en) * | 2012-11-14 | 2014-05-21 | 沈锋艳 | Preparation method of preparation for clearing away summer-heat and eliminating toxin |
| CN102960565B (en) * | 2012-11-28 | 2014-07-09 | 江汉大学 | Natural plant chicken heat stress resistant feed addictive and preparation method thereof |
| CN106344842A (en) * | 2016-08-26 | 2017-01-25 | 山东医学高等专科学校 | Soup with effects of clearing summer heat and activating spleen and preparation method thereof |
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Non-Patent Citations (1)
| Title |
|---|
| 中华人民共和国卫生部药品标准中药成方制剂第八册 中华人民共和国卫生部药典委员会，177 1993 * |
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Owner name: ANBANG PHARMACEUTIC CO., LTD., HUNAN PROV. Free format text: FORMER OWNER: ZHANG JIAYI Effective date: 20120621 |
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Free format text: CORRECT: ADDRESS; FROM: 410000 CHANGSHA, HUNAN PROVINCE TO: 410329 CHANGSHA, HUNAN PROVINCE |
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Effective date of registration: 20120621 Address after: 410329 Liuyang biological medicine Park, Hunan Province Patentee after: Anbang Pharmaceutic Co., Ltd., Hunan Prov. Address before: 410000 Ruifeng Road, Station North Road, Changsha, Hunan Patentee before: Zhang Jiayi |
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Address after: No.283 Kangning Road, Liuyang economic and Technological Development Zone, Changsha City, Hunan Province Patentee after: Hunan Anbang Pharmaceutical Co., Ltd Address before: 410329 Liuyang biological medicine Park, Hunan Province Patentee before: HUNAN ANBANG PHARMACEUTICAL Co.,Ltd. |