CN1682863A

CN1682863A - Plumepoppy injection

Info

Publication number: CN1682863A
Application number: CN 200510020409
Authority: CN
Inventors: 郁建生
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-02-25
Filing date: 2005-02-25
Publication date: 2005-10-19
Anticipated expiration: 2025-02-25
Also published as: CN1299712C

Abstract

The present invention discloses a kind of veterinary plumepoppy injection prepared with plumepoppy and andrographis herb. The veterinary plumepoppy injection has the functions of clearing away heat and toxic material, eliminating swelling, resisting bacteria and viruses, and diminishing inflammation. It is used in treating animal's flu, upper respiratory tract infection, digestive tract infection, epidemic gastroenteritis, virus infection, etc. The veterinary medicine has convenient use, wide application range, fast acting, obvious curative effect, stable quality, no toxic side effect and no residue, and is suitable for producing green product.

Description

Macleaya cordata injection

The present invention relates to two kinds of Chinese herbal medicine of a kind of usefulness fully natural green veterinary drug compound injection that compatibility is made behind effective component extracting, belong to control livestock disease goods field.

At present, the veterinary drug that the treatment poultry catch is a lot, but the overwhelming majority is a chemical drugs, easily in the poultry body, have residual after the use, produce toxic and side effects and more and more serious to the healthy phenomenon of people's the healthy potential safety hazard that exists, particularly antibacterials residual directly harm people in livestock products by livestock products food.

The objective of the invention is to: provide a kind of from natural plants effective component extracting, through the Chinese herb compound injection for animals that science compatibility, processing and refining form, be a kind of fully natural green veterinary drug product with effects such as clearing heat, releasing toxin, removing swelling, anti-inflammation antiviral.Do not produce any toxic side effects after its uses, noresidue, easy to use, evident in efficacy, steady quality, applied range, to overcome the deficiency of existing medicine.

The present invention is achieved in that it is by Herba Macleayae Cordatae, Herba Andrographis refining the forming of production technology through ethanol step impregnation effective component extracting, hybrid combination, the remove impurity of cold and hot processing precipitation.

1. get the dry product system coarse powder of Herba Macleayae Cordatae fruit or root, 30～40 ℃ of each dippings of the ethanol with 75%, 85% extract 2 times (the ethanol consumption is three times of medical material amount), each 24～48h; Merge alcohol extract, filtration, decompression filtrate recycling ethanol makes to contain the alcohol amount and reach at 20%～30% o'clock and end filtered while hot; Leave standstill filtration behind 2～4 ℃ of cold preservation 24～48h, transfer PH3～4 with 10% sulphuric acid liquid, filtrate is heated to 80～90 ℃ of backflow 30min, filtered while hot, and the tween 80 of adding injection total amount 0.5～1%, 24h after-filtration, filtrate for later use are left standstill in cold preservation.

2. get Herba Andrographis herb system coarse powder, 30～40 ℃ of each dippings of the ethanol with 80%, 90% extract 2 times (the ethanol consumption is three times of medical material amount), each 24～48h; Merge alcohol extract, filtration, add alcohol extract total amount 0.5～1% activated carbon and stir, decompression filtrate recycling ethanol reaches at 50%～60% o'clock only, the filtered while hot de-carbon to containing the alcohol amount; Filtrate adds 4MNaSO ₃80～90 ℃ of backflow 30min behind liquid 100ml, the 10% sulphuric acid liquid 100ml, filtered while hot; 2～4 ℃ of cold preservation 24～48h after-filtration are transferred PH4～5 with 10% sulphuric acid liquid, add the tween 80 of injection total amount 0.5～1%, and 24h after-filtration, filtrate for later use are left standstill in cold preservation.

3. getting the 1. liquid for preparing is heated to 2. liquid mix homogeneously and boils, filtration is left standstill in cold preservation, add benzyl alcohol, antioxidant is an amount of, transfer PH3～5, add the injection water to capacity, make finished product contain active ingredient macleaya cordata total alkaloid 0.2～0.4%, total andrographolides 0.1～0.3%, fine straining, fill, sealing by fusing, sterilization, quality inspection, packing.

The present invention compared with prior art has following advantage:

(1) applied range.It can be used for treating various domestic animal influenzas, upper respiratory tract infection, pneumonia, pig lung plague, digestive tract infection, transmissible gastroenteritis, diarrhoea dysentery, yellow scour of piglet Hakuri, high febrile illness, viral infection, fowl cholera, Pullorum Disease etc., good effect, instant effect.

(2) the present invention extracts the refining fully natural green veterinary drug product that forms of two kinds of Chinese herbal medicine effective ingredients science compatibilities, pleiotropy, amphitropic traditional compatibility advantage that the Chinese herb compound combined effect is cured the disease and regulated have promptly been brought into play, modern science and technology have been embodied again to the refining advantage of Chinese herbal medicine, not only easy to use, applied range, evident in efficacy, and without any side effects, noresidue, safe and reliable, compound " green product " developing direction.

(3) technological process science of the present invention is succinct, has adopted ethanol step impregnation effective component extracting, hybrid combination, cold and hot processing to precipitate refining the forming of production technology of remove impurity.Constant product quality, clarity is good, is suitable for suitability for industrialized production, and packing of product transportation is easy to carry.

Embodiments of the invention:

1. get six kilograms of the dry product system coarse powder of Herba Macleayae Cordatae fruit or root, each floods 2 times (the ethanol consumption is three times of medical material amount) of extraction, each 24～48h 30～40 ℃ of ethanol with 75%, 85%; Merge alcohol extract, filtration, decompression filtrate recycling ethanol makes to contain the alcohol amount and reach at 20%～30% o'clock and end filtered while hot; Leave standstill filtration behind 2～4 ℃ of cold preservation 24～48h, transfer PH3～4 with 10% sulphuric acid liquid, filtrate is heated to 80～90 ℃ of backflow 30min, filtered while hot, and the tween 80 of adding injection total amount 0.5～1%, 24h after-filtration, filtrate for later use are left standstill in cold preservation.

2. get four kilograms of Herba Andrographis herb system coarse powder, 30～40 ℃ of each dippings of the ethanol with 80%, 90% extract 2 times (the ethanol consumption is three times of medical material amount), each 24～48h; Merge alcohol extract, filtration, add alcohol extract total amount 0.5～1% activated carbon and stir, decompression filtrate recycling ethanol reaches at 50%～60% o'clock only, the filtered while hot de-carbon to containing the alcohol amount; Filtrate adds 4MNaSO ₃80～90 ℃ of backflow 30min behind 100ml, the 10% sulphuric acid liquid 100ml, filtered while hot; 2～4 ℃ of cold preservation 24～48h after-filtration are transferred PH4～5 with 10% sulphuric acid liquid, add the tween 80 of injection total amount 0.5～1%, and 24h after-filtration, filtrate for later use are left standstill in cold preservation.

3. get the 1. liquid for preparing and be heated to 2. liquid mix homogeneously and boil, filtration is left standstill in cold preservation, adds the benzyl alcohol of injection total amount 1%, the NaHSO of injection total amount 0.2% ₃Antioxidant is transferred PH3～5, adds the injection water to capacity, makes finished product contain active ingredient macleaya cordata total alkaloid 0.2～0.4%, total andrographolides 0.1～0.3%, fine straining, fill, sealing by fusing, sterilization, quality inspection, packing.

Claims

1, a kind of pure natural animal compound Macleaya cordata injection, be a kind of for animals green Chinese herbal and crude drugs preparations with wide spectrum clearing heat, releasing toxin, removing swelling, anti-inflammation antivirus action, it is to be made with extra care through the production technology of ethanol step impregnation effective component extracting, hybrid combination, the remove impurity of cold and hot processing precipitation by 60% Herba Macleayae Cordatae, 40% Herba Andrographis to form.It is characterized in that:

2. get Herba Andrographis herb system coarse powder, 30～40 ℃ of each dippings of the ethanol with 80%, 90% extract 2 times (the ethanol consumption is three times of medical material amount), each 24～48h; Merge alcohol extract, filtration, the activated carbon that adds alcohol extract total amount 0.5～1% stirs, and decompression filtrate recycling ethanol reaches at 50%～60% o'clock only, the filtered while hot de-carbon to containing the alcohol amount; Filtrate adds 4MNaSO ₃80～90 ℃ of backflow 30min behind liquid 100ml, the 10% sulphuric acid liquid 100ml, filtered while hot; 2～4 ℃ of cold preservation 24～48h after-filtration are transferred PH4～5 with 10% sulphuric acid liquid, add the tween 80 of injection total amount 0.5～1%, and 24h after-filtration, filtrate for later use are left standstill in cold preservation.

3. getting the 1. liquid for preparing is heated to 2. liquid mix homogeneously and boils, filtration is left standstill in cold preservation, add the benzyl alcohol of injection total amount 1%, 0.2% antioxidant, transfer PH3～5, add the injection water to capacity, make finished product contain active ingredient macleaya cordata total alkaloid 0.2～0.4%, total andrographolides 0.1～0.3%, fine straining, fill, sealing by fusing, sterilization, quality inspection, packing.

2, be used for the treatment of fowl cholera, Pullorum Disease, pig erysipelas.